( ) Cost chart? ANALGESICS Analgesic combinations ( ) How to choose between? ( ) Relative Strength ( ) Levels of Control Anacin (caffeine/ASA) 1-2 PO q4h Darvocet (propox/acetamin) 1-2 PO q4h [N-50,N-100] Darvon Comp. (propox/caff/ASA) 1-2 PO q4h Esgic (butalb/caff/acetamin) 1-2 PO q4h Fioricet (butalb/caff/acetamin) 1-2 PO q4h Fiorinal (butalb/caff/ASA) 1-2 PO q4h Talwin Comp. (pentaz/ASA) 1-2 PO q4h Tylenol w/ Cod. (codeine/acetamin) 1-2 PO q4h 7.5 mg [#1],15 mg [#2], 30 mg [#3], 60 mg [#4]) Pediatric elixir (acetamin/cod) 5ml/dose if 3-6 yo, 10ml/dose if 7-12 yo Lorcet (hydrocod/acetamin) 1-2 PO q4-6h Lortab (hydrocod/acetamin) 1-2 PO q4-6h [5,7.5] Vicodin (hydrocod/acetamin) 1-2 PO q4-6h Percodan (oxycod/ASA) 1 PO q6h Percocet (oxycod/acetamin) 1 PO q6h Tylox (oxycod/acetamin) 1 PO q6h Soma Comp. (carisoprodol/ASA) 1-2 PO qid Norgesic (orphenadrine/caff/ASA) 1-2 PO tid/qid Local anesthetics ( ) When to not use epi ( ) Allergic rxn common? lidocaine (Xylocaine) 0.5,1,1.5,2,4,10,20% with epi 0.5,1,1.5,2% Muscle relaxants ( ) How to choose between? ( ) Relative strengths ( ) Different in drowsiness methocarbamol (Robaxin) 1000-1500 mg PO cyclobenzaprine (Flexeril) 10 mg PO carisoprodol (Soma) 350 mg PO ( ) Potentially addictive? baclofen (lioresal) Start 5 mg PO diazepam (Valium) 2-10 mg PO dantrolene (Dantrium) 25-50 mg PO quinine: 260-300 mg PO Commonly prescribed for leg cramps ( ) Actually effective for leg cramps? qid tid tid/qid [500,750] [10] [350] tid, max 80mg/day. [10,20] tid/qid [2,5,10] bid/qid [25,50,100] qhs [200,260,300,325] Narcotics (pure) ( ) Relative strengths ( ) Indications codeine hydromorphone (Dilaudid) propoxyphene (Darvon) Sust. release (MS Contin) 0.5 1-2 65 10-30 butorphanol (Stadol) fentanyl (Sublimaze) meperidine (Demerol) morphine sulfate alfentanil (Alfenta) nalbuphine (Nubain) pentazocine (Talwin) naloxone (Narcan) 1 mg IV increments or 1-4 mg IM q3-4h IV increments of 2-3 ug/kg up to 50 ug. Lasts 1-2h 25 mg IV increments. 1-1.5 mg/kg up to 150mg IM/PO q3-4h. [tabs 50,100, syrup 50 mg/5ml] 0.1-0.2 mg/kg up to 2-5 mg increments IV. 5-20 ug/kg IV increments. 5-10 mg IV/IM q3-6h 30 mg IV/IM q3-4h 0.4-2.5 mg or more IV/IM/SC/ET. Antagonist mg/kg up to 60 mg PO/IM q4-6h mg PO/IM/PR q4-6h mg PO q4h mg PO q4-8h Nonsteroidal anti-inflammatories aspirin (Ecotrin, Bayer, ASA) ketorolac (Toradol) 650 mg 10 mg load 30-60 mg Trilisate (salicylate combo) 1 tab ibuprofen (Motrin, Advil, Nuprin) 300-800 mg Peds 5-10 mg/kg naprox sodium(Anaprox) 275 mg indomethacin (Indocin) 25-50 mg flurbiprofen (Ansaid) 50-100 mg naproxen (Naprosyn) 250-500 mg dicloenac (Voltaren, Cataflam) 50 mg XR 100 mg sulindac (Clinoril) 150-200 mg diflunisal (Dolobid) 1g then 500 mg nabumetone (Relafen) 1000 mg piroxicam (Feldene) 20 mg [15,30,60] [1,2,3,4, supp 3] [32,65] [tabs 30,60 elixir 10 & 20 mg/5ml] PO q4-6h [65,75,81,325,500,650, supp 60,120,325,650] PO q4-6h [10] IM, then 15-30 mg IM q6h. PO q4-8h. [500,750,1000, liquid 500 mg/5ml] PO qid. [200,300,400,600,800] PO q6h. [100 mg/5ml] PO tid/qid [275,550] tid [25,50, supp 50, susp 25mg/5ml] PO bid/qid [50,100] PO bid/tid [250,375,500, susp125 mg/5ml] PO bid/tid [25,50,75] PO qd PO bid [150,200] PO bid [250,500] PO qd/bid [500,750] PO qd [10,20] Other analgesics acetaminophen (Tylenol) 650 mg PO/PR q4h. Peds: 15 mg/kg/dose. [tabs 80,160,325,500] [supp 120,325,650] [elixir 160 mg/5ml] [drops 80 mg per 0.8 ml dropperful] lidocaine, viscous (xylocaine 2%) 15 ml PO q3h. Peds: 5ml per dose for a 20 kg child [50,100,450ml bottles] phenazopyridine (Pyridium) 200 mg PO tid for 2 days [100,200] ANTIMICROBIALS Aminoglycosides gentamicin neomycin (Garamycin) Load 2 mg/kg IV/IM, maintenance 1 mg/kg q8h. Peak 4-6 ug/ml, trough 1-2 ug/ml (Mycifradin) 1 g PO q4h [tab 500, solution 125 mg/5ml] 300 mg IM q6h. streptomycin: dosage varies Antifungal agents amphotericin B (Fungizone) Test dose 1 mg slow IV. Then begin 0.25 mg/kg IV qd and gradually advance to 1-1.5 mg/kg clotrimazole (Gyne-Lotramin Mycelex-G) Oral troches 5 times/day x 14 days [10] vaginal candidiasis 1% cream bid for 7 days, or supp 100 mg qhs x 7 days or 200 qhs x 3d or 500 qhs x 1d [supp 100,500] fluconazole (Diflucan) 200-400 IV/PO first day, then 100-200 mg qd. [50,10,200] griseofulvin (Fulvicin) 500 mg PO qd. Peds 11 mg/kg/day. [tabs125,250,500, susp 125 mg/5ml] ketoconazole (Nizoral) 200-400 mg PO qd [200] Hepatic toxicity miconazole (Monistat) Vagina 2% cream qhs x7d or 100 mg supp qhs x 7 days or 200 qhs x 3d [supp 100,200] nystatin (Mycostatin) 4-6 ml PO swish + swallow qid [100,000 units/ml] Infants: 2 ml/dose. [50 ml bottle] Vaginal supp qhs for 14 days. [100,000 units] Antimalarial agents chloroquine phos. (Aralen) Malaria prophylazis exposure [250,500] mefloquine (Lariam) Malaria prophylaxis after. Treatment 1250 mg PO single dose [250] Fansidar (pyrimethamine/sulfadoxine) Acute malaria quinine (Quinamm) 8 mg/kg up to 500 mg PO qwk from 1 wk before exposure to 4 wks post 250 mg PO q week from 1 week before exposure to 4 weeks 2-3 tabs PO. Prophylaxis 1 tab PO q week. Dermal reactions. 650 mg PO tid [200,260,325] Antiparasitic agents mebendazole (Vermox) Pinworm 100 mg PO single dose. Roundowrm, whipworm, hookworm: 100 mg PO bid x 3 days [100] Antituberculous agents isoniazid (INH) 10-20 mg/kg up to 300 mg PO qd Consider supplemental pyridoxine 25 mg PO qd. Hepatic toxicity. rifampin (Rimactane) 10-20 mg/kg up to 600 mg PO/IV qd ethambutol (Myambutol) 15 mg/kg PO qd pyrazinamide 20-35 mg/kg/day PO divided tid/qid dapsone 50-100 mg PO qd [50,100,300, syrup 50 mg/5ml] [150,300] [100,400] [500] [25,100] Antiviral agents acyclovir (Zovirax) Genital herpes: Zoster: Varicella: amantadine (Symmetrel) vidarabine (Vira-A) zidovudine (AZT, Retrovir) 5-10 mg/kg 200 mg 800 mg 20mg/kg to 100 mg constant 100-200 mg IV PO PO 800mg PO PO bid IV infusion PO/IV q4h. Cephalosporins - 1st generation cephalexin (Keflex) 250-500 mg PO Peds: 75-100 mg/kg/day cefazolin (Ancef, Defzol) 0.5-2 g IV/IM Peds: 25-100 mg/kg/day divided q8h, each dose over 1h. 5 times/day for 10 days. 5 times/day for 7-10 days. qid for 5 days [tabs 200,800, suspension 200 mg/5ml] [100, syrup 50mg/5ml] totalling 15 mg/kg/day [tab 100, syrup 50 mg/5ml] Marrow suppression qid. [250, 500] divided qid [elixir 125 & 250 mg/5ml] q6-8h. q6-8h. Cephalosporins - 2nd generation cefaclor (Ceclor) 250 mg PO tid. [tabs 250,500] Peds 20-40 mg/kg/day divided tid. [elixir 125,187,250, & 375 mg/5ml] cefoxitin (Mefoxin) 1-2 g IV/IM q6-8h Cephalosporins - 3rd generation cefixime (Suprax) 400 mg PO qd or 200 bid [200,400] Peds: 8 mg/kg/day divided qd/bid [susp 100 mg/5ml] cefoperazone (Cefobid) 2-4 g IV q12h. Clotting impairment. cefotaxime (Claforan) 1-2 g IV q4-8h. Peds: 50-180 mg/kg/day divided q4-6h IV. Meningitis may require higher doses. ceftazidime (Fortaz) 1-2 g IV q8-12h. ceftriaxone (Rocephin) 1-2 g IV/IM q24h. Gonorrhea: 1 dose 250 mg IM. Peds 50-75 mg/kg/day (max 2g) divided q12-24h. 100 mg/kg/day (max 4g) for meningitis. Fluroquinolones Ciprofloxacin (Cipro) lomefloxacin ofloxacin 250-750 200-400 (Maxaquin) 400 (Floxin) 200-400 200-400 mg mg mg mg mg Macrolides azithromycin (Zithromax) 500 mg 1000 mg clathromycin (Biaxin) 250-500 mg PO IV PO PO IV bid [250,500,750] q12h. qd [400] bid [200,300,400] q12h, each dose over 1h. PO first day, then 250 mg PO qd. [250] PO single-dose for chlamydia. PO bid [250,500] Pediazole (EES/STX) 50 mg/kg/day PO divided qid (based on EES dose) Penicillins - 1st generation (natural) Penicillin V (Pen-Vee) 250-500 mg PO qid. Peds 25-50 mg/kg/day divided qid [125,250,500, elixir 125 & 250 mg/5ml] penicillin G 12-24 million units/d IV divided q4-6h. Procaine (Wycillin) 0.5-1.2 million units IM, duration 24 hrs. Benzathine 1.2 million units IM, duration 2-4 weeks Penicillins cloxacillin dicloxacillin Peds: methicillin 2nd generation (penicillinase-resistant) (Cloxapen) 250-500 mg PO qid [250,500, liq 125 mg/5ml] (Dynapen) 125-500 mg PO qid [tabs 125,250,500] 12-25 mg/kg/day divided qid [elixir 62.5 mg/5ml] (Staphcillin) 1-2 g IV/IM q4-6h Penicillins - 3rd generation (aminopenicillins) amoxicillin (Amoxil) 250-500 mg PO Peds: 40 mg/kg/day divided amoxicillin clav (Augmentin) 250-500 mg PO Peds: 40 mg/kg/day divided ampicillin (Omnipen) 1-2g IM/IV 250-500 mg PO Peds: 50-200 mg/kg/day div ampicillin sulbactam (Unasyn) 1.5-3 g IV q6h Penicillins 4th generation (extended spectrum) piperacillin (Pipracil) 3-4 g IV/IM ticarcillin (Ticar) 3-4 g IV/IM Peds: 200-300 mg/kg/day div ticarcillin clav (Timentin) 3.1 g IV Sulfonamides Bactrim, Septra (TMS) Peds: Pediazole tid. [tabs 125,250,500] tid. [elixir 125 & 250 mg/5ml] tid. [tabs 125,250,500] tid. [elixir 125 & 250 mg/5ml] q4-6h qid. [250,500] qid [elixir 125 & 250 mg/5ml] q4-6h q3-6h q4-6h q4-6h 5 mg/kg 1 tab IV q6h. (based on trimethoprim) PO bid, single strength (80/400) or DS (160/800) 5ml elixir per 10 kg per dose PO bid [50/200 per 5ml] (EES+ sulfisoxazole) 50 mg/kg/day (based on EES dose) PO divided qid. Tetracyclines doxycycline (Vibramycin) 200 mg IV/PO initially, then 50-100 mg q12h [tabs 50,100, syrup 25 & 50 mg/5ml] tetracycline (Achromycin) 250-500 mg PO/IV/IM qid [tabs 250,500, susp 125 mg/5ml] Other antibiotics clindamycin Peds: vancomycin (Cleocin) 300-900 mg IV q6h. 150-450 mg PO qid. 8-40 500 500 Peds: 40 aztreonam (Azactam) 0.5-2 g chloramphenicol (Chloromycetin) 50-100 Pediatric Meningitis 50-100 imipenem-cilastin (Primaxin) 250-1000 metronidazole (Flagyl) Load 1g or 15 250-750 Single dose for trich: 2g nitrofurantoin (Macrodantin) 50-100 Peds: 5-7 (Vancocin) mg/kg/day divided qid [tabs 75,150, susp 75 mg/5ml] mg IV q6h each dose over 1h. mg PO qid. mg/kg/day [125,250] IV/IM q6-12h mg/kg/day IV/PO divided q6h. mg/kg/day [250, syrup 150 mg/5ml] Aplastic anemia mg IV/IM q6-8h, each dose over 20-60 min. mg/kg IV, maintenance 500 mg or 7.5 mg/kg 16h, each dose over 1h. mg PO tid. PO [250,500] mg PO qid. mg/kg/day divided qid [25,50,100, 25 mg/5ml] ----------------------------------------------------------------------------------------------------------------------CARDIOVASCULAR ACE inhibitors enalapril (Vasotec) 1.25 mg IV q6h 5-40 mg PO qd or divided bid. [5,10,20] captopril (Capoten) 6.25-25 mg PO bid/tid [12.5,25,50,100] benazepril (Lotensin) 10-40 mg PO qd [5,10,20,40] fosinopril (Monopril) 10-40 mg PO qd [10,20] lisinopril (Zestril) 10-40 mg PO qd [5,10,20,40] quinapril (Accupril) 10-20 mg PO qd [5,10,20,40] ramipril (Altace) 2.5-20 mg PO qd [1.25,2.5,5,10] Thrombolytics alteplase (TPA) 100 mg total dose - 10 mg IV bolus, infusion 50 mg in 1st hr, 20 mg in 2nd hr, 20 mg in 3rd hr. streptokinase (Streptase) 1.5 million units IV over 60 min. Antianginals nitroglycerin, sust release (Nitro-bid) 2.5-6.5 mg PO bid/tid [2.5,6.5,9] isosorbide dinitrate (Isordil) 10-40 mg PO qid [5,10,20,30,40] Sustained release 40-80 mg PO bid/tid [50] sublingual tabs: one prn [2.5,5,10] isosorbide mononitrate (ISMO) 20 mg PO twice per day 7h apart [20] nitroglycerin, sublingual (Nitrostat) 0.4 mg SL [0.15,0.3,0.4,0.6] nitroglycerin, IV infusion (Tridil) 50 mg in 250 ml D5@ (200 ug/ml) at 10-100 ug/min. 6ml/h = 20 ug/min nitroglycerin, spray (Nitrolingual) 1-2 oral sprays prn. nitroglycerin, topical oint 2% (Nitro-bid) 0.5-3 inches 14-8h (15 mg/inch) nitroglycerin, transderm 1 patch 1d [Doses in mg/h Nitro-Dur 0.1,0.2,0.4,0.6] Antidysrhythmics / Cardiac arrest disopyramide (Norpace) 100-150 mg PO qid [100,150] flecanide mexiletine quinidine SO4 tocainide procainamide (Tambocor) 100 mg PO bid [50,100,150] (Mexitil) 20-300 mg PO tid [150,200,250] (Quinidex) 300-600 mg PO bid/tid [300] Sustained release (Tonocard) 400-600 mg PO tid [400,600] (Procan SR) (Pronestyl-SR) 500-1000 mg PO qid or 50 mg/kg/day [250,500,750,1000] IV infusion: 100 mg IV q10min or run infusion below at 20 mg/min (150 ml/h) until 1) QRS or PR widens >50%, 2) Dysrhythmia suppressed, 3) Hypotension, or 4) Total of 17 mg/kg or 1000 mg. Infusion 2g in 250ml D5W (8 mg/ml) at 2-6 mg/min (15-45 ml/h) adenosine (Adenocard) 6 mg rapid IV, if no response after 1-2 minutes then 12 mg. A third dose of 12 mg may be given if necessary. amiodarone (Cordarone) Dosing varies [200] atropine 0.5-1.0 mg IV/ET. Peds 0.02 mg/kg/dose, minimum 0.1 mg bicarbonate Na 1 meq/kg up to 50-100 meq IV prn bretylium (Bretylol) Initial 5 mg/kg IV, then 10 mg/kg q15min up to maximum 30 mg/kg. Infusion 500 mg in 50ml D5W (10 mg/ml) at 1-3 mg/min (7-21 ml/h) digoxin (Lanoxin) (Lanoxicaps) Load 0.25 mg IV q6h up to 1 mg, Maint 0.125-0.25 mg IV/PO qd [Lanoxin 0.125,0.25,0.5, elixir 0.05 mg/ml, Lanoxicaps 0.05, 0.1,0.2] dig-immun Fab (Digibind) 2-20 vials IV [40 mg/vial] for dig toxicity epinephrine 0.5-1 mg IV/ET for cardiac arrest [1:10,000 solution] isoproterenol (Isuprel) 2 mg in 250 ml D5W (8 ug/ml) at 5 ug/min. 37 ml/h4 = 5 ug/min. Peds: 0.1-1 ug/kg/min. 10 kg: 8ml/h = 0.1 ug/kg/min lidocaine (Xylocaine) Load 1 mg/kg IV, then 0.5 mg/kg q8-10min to total 3 mg/kg. Maintenance 2 g in 250ml D5W (8 mg/ml) at 1-4 mg/min drip (8-30 ml/h) Peds: 20-50 ug/kg/min, 10 kg: 3ml/h = 40 ug/kg/min magnesium SO4 2 g in 50ml D5W/NS IV over 20 minutes Antilipid agents cholestyramine (Questran) clofibrate (Atromid-S) colestipol (Colestid) gemfibrozil (Lopid) probucol (Lorelco) lovastatin (Mevacor) 4 500 5-10 600 500 20-80 g mg g mg mg mg PO PO PO PO PO PO 1-6 x/day qid tid/qid bid bid qd [4 g bar or powder] [500] [5g] [300,600] [250,500] [10,20,40] Beta blockers atenolol (Tenormin) Acute MI metoprolol (Lopressor) esmolol (Brevibloc) life = 9 minutes propranolol (Inderal) labetalol b1: 50-100 5 b1: 5 50-100 b1b2: 5 B1B2: 1 40-80 (Trandate) a1B1B2: 20 100-400 Calcium channel blockers verapamil (Isoptin, Calan) mg PO qd mg mg mg g IV over 5 min, repeat in 10 min. increments IV up to 15 mg. PO bid [50,100] in 500ml (10 mg/ml) at 50-200 ug/kg/min. 70 kg: 40ml/h = 100 ug/kg/min. Half- mg mg mg mg increments IV. PO bid/tid/qid [tabs 10,20,40,60,80,90] IV q10min up to 300 mg. PO bid [100,200,300] 0.1-0.3 80-120 2.5-5 30-90 60-120 isradipine (DynaCirc) diltiazem (Cardizem) Sust. rel (Cardizem SR) (Cardizem CD) (Dilacor XR) 180-240 0.25 mg/kg or 20 nifedipine (Procardia, Adalat) 10-30 Sust rel. (Procardia XL) 30-60 mg/kg mg PO mg PO mg PO mg PO up to 5-10 mg IV over 2 min. tid [40,80,120] bid [2.5,5] qid [30,60,90,120] bid [60,90,120] and other mg mg mg mg qd [180,240,300] over 2 min, repeat in 15 min prn. Infusion 5-15 mg/h tid [10,20] qd [30,60,90] PO IV PO PO Combination antihypertensives Capozide (captopril/HCTZ 25/15, 25/25, 50/15, 50/25) Lopressor HCT (metoprolol/HCTZ, 50/25, 100/25, 100/50) Dyazide (HCTZ/triamterene 25/50) Aldactazide (HCTZ/spironolactone 25/25, 50/50) Maxzide (HCTZ/triamterene 50/75, 25/37.5) Diuretics acetazolamide (Diamox) bumetanide (Bumex) furosemide. Loop furosemide (Lasix) 250 0.5-2 [25,50,100] 1 tab 1 tab 1-2 tabs 1-2 tabs 1 tab PO PO PO PO PO bid bid qd/bid qd qd mg IV/PO qd/bid/tid [125,250,500] Carbonic anhydrase inhibitor mg PO/IV/IM qd [0.5,1,2] 1 mg bumetanide is roughly equivalent to 40 mg 1 mg/kg up to 20-40 mg IV. [solution 10 & 40 mg/5ml] 20-80 mg PO qd/bid. [20,40,80] Loop hydrochlorothiaz (HCTZ) 25-100 mg PO qd or bid spironolactone (Aldactone) 25-50 mg PO qd/bid triamterene (Dyrenium) 100 mg PO bid [25,50,100, solution 50 mg/5ml] Thiazide [25,50,100] K-sparing [50,100] K-sparing Other antihypertensives clonidine Transdermal methyldopa prazosin reserpine (Catapres) (Catapress-TTS) (Aldomet) (Minipress) (Serpasil) 0.1-0.3 mg PO 1 patch 1 wk 250-1000 mg PO 1-5 mg PO 0.1-0.25 mg PO bid [0.1,0.2,0.3] [Sizes 0.1,0.2,0.3 mg/day] qid [tabs 125,250,500, susp 250 mg/5ml] bid/tid [1,2,5] qd [0.1,0.25,1] doxazosin (Cardura) 1 mg PO qd [1,2,4,8] hydralazine (Apresoline) 20-40 mg IV/IM q4-6h, 10-50 mg PO qid [10,25,50,100] diazoxide (Hyperstat) 1-3 mg/kg up to 150 mg IV q5-15 min minoxidil (Loniten) 5-20 mg PO qd [2.5,10] nitropruss Na (Nipride) 50 mg in 250 ml D5W (200 ug/ml) 0.5-10 ug/kg/min. 70 kg: 20 ml/h = 1 ug/kg/min. Cyanide toxicity can develop with infusions > 10 ug/kg/min, check thiocyanate levels. Pressors / Volume expanders dobutamine (Dobutrex) dopamine (Intropin) ug/kg/min. Doses in ug/kg/min: 2-5 ephedrine epinephrine Peds: Infusion: phenylephrine (Neo-Synephrine) 160ml/h) albumin dextran weight = 6% sol'n hetastarch norepinephrine plasma prot fract (Albuminar) [500 ml] (Hespan) (Levophed) (Plasmanate) DERMATOLOGY Antimicrobial agents (topical) acyclovir (Zovirax) bacitracin 250 mg in 250ml D5W(1 mg/ml) at 2.5-15 ug/kg/min. 70 kg: 25 ml/h = 5 ug/kg/min 400 mg in 250ml D5W(1600 ug/ml) at 2-20 ug/kg/min. 70 kg: 13 ml/h = 5 = dopaminergic, 5-10 = beta, > 10 alpha 5-10 mg IV q5-10 min prn 0.5-1 mg IV/ET of 1:10,000 sol'n for cardiac arrest. 0.01 mg/kg up to 0.5 mg. 1 mg in 250 ml D5W (4ug/ml) at 1-4 ug/min (15-60 ml/h) 100-500 ug increments IV, 20 mg in 250ml D5W (80 ug/ml) at 40-180 ug/min (35500 20 ml of 5% solution IV prn [50,250,500,1000 ml] ml/kg up to 500 ml IV. Low molecular weight = 10% sol'n, high molecular 500-1000 ml IV 6% sol'n [500ml] 4 mg in 500ml D5W (8ug/ml) at 2-4 ug/min. 20 mg/h = 3 ug/min 5% sol'n 250-500 ml IV prn [250,500 ml vials] 5% ointment 6 times/day x 6 days [Tubes 3,15g] apply ointment 1-3 times daily chloramphenicol gentamicin lindane mupirocin Neosporin clotrimazole ketoconazole miconazole nystatin Polysporin tolnaftate amphotericin B silver sulfadiazine (Chloromycetin) (Garamycin) (Kwell) 1% cream tid/qid 0.1% cream/ointment tid/qid 30ml of 1% cream or lotion topically from chin to feet, wash after 8-12h. 1% shampoo 30 ml per application [60ml for all forms] Lice, mites. (Bactroban) 2% ointment tid for 3-5d [15g tube] (bacitr/neo/poly) cream or ointment 2-5 times per day. (Lotrimin, Mycelex) 1% cream/solution/lotion bid. (Nizoral) 2% cream qd (Monistat) 2% cream/pwdr/lotn/spray bid (Mycostatin) cream/ointment/powder bid/tid (bacitr/poly) ointment/aerosol/powder 2-5 times per day. (Tinactin) 1% cream/powder/solution/aerosol/liquid bid (Fungizone) 3% cream/lotion/ointment bid/qid (Silvadene) 1% cream applied qd/bid to burn. [20,50,400,1000g] Corticosteroids (topical) dexamethasone (Decadron) 0.1% cream bid hydrocortisone Apply tid/qid methylprednisolone (Medrol) tramcinolone (Kenalog) Other calamine capsaicin coal tar istretinoin minoxidil oatmeal (Zostrix) (Tegrin) (Accutane) (Rogaine) (Aveeno) [cream 0.25, 0.5, 1, 2.5%] [ointment 0.5,1,2.5%] [lotion 0.25,0.5,1,2,2.5%] [gel 0.5%, sol'n 1%] [aerosol 0.5%] ointment bid/qid [0.25, 1%] Apply tid/qid [ointment 0.025, 0.1, 0.5%] [cream 0.025, 0.1, 0.5%] [lotion 0.025] [0.1% aerosol] apply lotion apply .025% or .075% cream apply shampoo 0.5-2 mk/kg/day PO divided 1 ml of 2% soln to dry scalp apply lotion qid prn for poison ivy/oak qhs daily. bid [10,20,40] bid qid prn. Poison ivy/oak ----------------------------------------------------------------------------------------------------------------------ENDOCRINE AND METABOLIC Corticosteroids betamethasone cortisone hydrocortisone (Celestone) (Cortone) (Cortef) 0.5-9.0 25-300 100-500 20-240 dexamethasone (Decadron) 0.75-9 methylprednisolone (Solu-Medrol) 125 mg mg mg mg/day mg/day mg IM/PO qd. [0.6, syrup .6 mg/5ml] PO qd [5,10,25] IV q4-6h [susp 10 mg/5ml] PO divided [5, 10,20] PO/IV/IM, divided q6h. [0.25,0.5,0.75,1.0,1.5,2,4,6, elixir 0.5 mg/5ml] IV/IM, dosage varies. Medrol Dosepack tapers prednisolone prednisone (Deltasone) triamcinolone (Aristocort) (Kenalog) 4-48 mg PO qd [2,4,8,16,24,32] 24 to 0 mg over 7 days. 5-60 mg PO/IV/IM qd [tab 5, liquid 5 & 15 mg/5ml] 1-2 mg/kg or 5-60 mg PO qd [tabs 1,2.5,5,10,20,50, elixir 5 mg/5ml] 4-48 mg PO/IM qd [tabs 1,2,4,8, syrup 4 mg/5ml] Diabetes-related agents glipizide tolbutamide glyburide (Glucutrol) 5-15 mg (Orinase) 500 mg (Micronase) (DiaBeta) 2.5-5 mg Micronized glyburide (Glynase PresTab) 1.5-3 chlorpropamide (Diabinese) 100-500 mg PO qd/bid [5,10] PO qd/bid [250,500] PO qd/bid [1.25,2.5,5] mg PO qd [1.5,3] PO qd [100,250] insulin (Novolin) (Humulin) 5-10 units regular plus concurrent dextrose IV for hyperkalemia. Profound hyperglycema (e.g. DKA) 0.1 units regular/kg IV bolus, infusion 100 units regular in 500ml NS (0.2 units/ml) allow 100ml to drain and prime tubing prior to hook-up) at 0.1 units/kg/hr. 70 kg: 7 units/h (35 ml/h) glucagon dextrose administration. (D-50-W) Sex steroids / Androgens estrogens, conjugated (Premarin) finasteride (Proscar) 1 0.5-1 mg IM/SC if no IV for dextrose. Onset 5-20 min. g/kg (1-2 ml/kg) up to 25 g (50ml) of 50% solution IV. Dilute before pediatric 25 mg IV/IM prn 0.625-1.25 mg PO qd first 3 weeks of each month. [0.3,0.625,0.9,1.25,2.5] apply cream qd [0.625 mg/g] 5 mg PO qd [5] levonorgestrel (Norplant) 6 implants subdermal q 5 years. ethinyl estradiol/norethindrone (Loestrin) 20 ug/1 mg, 30 ug/1.5 mg) Use as directed. Loestrin Fe adds 75 mg ferrous fumarate. medroxyprogesterone (Provera) 5-10 mg PO qd prn [2.5,5,10] Parenteral contracept (Depo-Provera) 150 mg IM q3 months. norethindrone/ethinyl estradiol (Norinyl) 1+35 (1 mg/35 ug) (Tri-Norinyl) (Triphasic) Use as directed. norethindrone/ethinyl estradiol (Ortho-Novum) 1/35 (1mg/35 ug) (Ortho-Novum) 1/50 (1 mg/50 ug) (Ortho-Novum) 7/7/7 (triphasic) tamoxifen (Nolvadex) 10-20 mg PO bid [10] levonorgestrel + ethiny estradiol, triphasic (Triphasil) Use as directed Thyroid agents thyroxine (T4, Synthroid) 100-200 ug PO qd [25,50,75,88,100,112,125,150,175,200,300ug] thyroid, dessicated (Thyroid USP) 60-120 mg PO qd [15,30,60,90,120,180, 240,300] propylthiouracil (PTU) 50-150 mg PO tid/qid [50] Vitamins, minerals, and nutritionals thiamine (vitamin B1) 100 mg IV/IM/PO qd [50,100,250,500] niacin (vitamin B3) 10-20 mg PO qd [25,50,100,250,500] cyanocobal (vit. B12) 100-200 ug IM q month. ascorbic acid (vitamin C) 50-250 mg PO qd [25,50,100,250,500,1000] calcitriol (vitamin D) 0.5-2 ug PO qd [0.25,0.5 ug] vitamin D (Os-Cal+D) [250,500] calcium carb (Os-Cal) 250-3000 mg PO qd [500] With added calcium Cl 100-1000 mg slow IV of 10% sol'n [amp 1000 mg/10ml] calcium gluconate 100-1000 mg slow IV of 10% sol'n [ampule 1000 mg/10ml] 500-1000 mg PO bid/qid [500] 25-100 ug PO qd [25,50,100,25 ug] phosphate (K-Phos) 1-2 tabs PO tid/qid [250] potassium: IV infusion 10-40 meq/h. K-Dur tab 5-25 meq PO qd [10,20] folic acid (Folvite) 0.4-1 mg IV/IM PO qd [0.1,0.4,0.8,1] formulas, infant: milk based (Enfamil, Similac, SMA) or soy based (Isomil, Prosobee, Soyalac) magnesium gluconate 250-500 mg PO qd [250,500] multivitamins (MVI) 1 ampule diluted in 500-1000 ml NS/D5WIV. 1 tab PO qd. rehydration solutions Pedialyte Other endocrine and metabolic agents colchicine 2mg IV over 2-5 min for acute gout 0.6 mg PO qd [0.6] probenecid (Benemid) 500-1000 mg PO qd/bid [500\ single-dose 1 g PO when used with penicillin injections. desmopressin (DDAVP) D.I. 0.1-0.2 ml intranasally bid, or 2-4 ug IV/SC q12h. Hemophilia 0.3 ug/kg IV over 15-30 min. sodium polystyrene sulfonate (Kayexalate) Hyperkalemia. 15-60 g PO or 30-50 g retention enema (in sorbitol) 16h prn vasopressin (Pitressin, ADH) 5-10 units IM/SC/intranasal qid prn ----------------------------------------------------------------------------------------------------------------------ENT Antihistamines (pure) fexofenadine astemizole clemastine terfenadine (Allegra-D) (Hismanal) (Tavist) (Seldane) 60 30 1.34 60 brompheniramine (Dimetane) 4 chlorpheniramine (Chlor-Trimeton) 4 dimenhydrinate (Dramamine) 50 diphenhydramine (Benadryl) Peds: hydroxyzine promethazine Peds: (Atarax) (Vistaril) (Phenergan) mg mg mg mg PO bid [60] PO 1st day, 20 2nd day, then 10 qd [10] PO bid [1.34,2.68, syrup 0.5 mg/5ml] PO bid [60] mg PO 14-6h. [tab 4, elixir 2 mg/5ml] Time release 8-12 mg PO bid [8,12] mg PO 14-6h [tabs 2,4, syrup 2mg/5ml] Time release 8-12 mg PO bid [8,12] mg PO/IM/IV q4h. [50] 25-50 mg IV/IM/PO q6h. [tabs 25,60] 5mg/kg/d. [elixir 12.5 mg/5ml] 0.5 mg/kg up to 25-50 mg PO/IM q4-6h prn. [tabs 10,25,50,100, susp 10 & 25 mg/5ml] 25-50 mg PO/IM/PR 14-6h. [tabs 12.5,25,50] 1 mg/kg/dose [syrup 6.25 & 25 mg/5ml, supp 12.5,25,50] Antitussives (pure) guaifenesin (Robitussin) 5-20 ml PO q4h, 5-10ml/dose if 6-12 yo, 2.5-5ml if 2-6 yo [syrup 100 mg/5ml] Combinations-antihistamines/decongestants/antitussives Tavist-D (clemastine 1.34 mg+phenylpropanolamine 75 mg) Sudafed Plus (pseudoephed 60 mg + chlorpheniramine 4 mg per tab or 10ml) Actifed (triprolidine 2.5 mg + pseudoephedrine 60 mg in 1 tab or 10ml syrup): 1 PO bid 1 tab or 10ml PO 14-6h 1 tab or 10ml PO 14-6h, 5ml if 6-12 yo. Sustained release (5/120): 1 tab PO bid. Dimetapp (brompheniramine/phenylpropanolamine) 1 tab or 10ml PO 14-6h, 5 ml/dose if 6-12 yo, 2.5 ml/dose if 2-6 yo. [tabs 4/25, elixir 2/12.5 per 5ml] Sust. release (Dimetapp Extentabs) 1 PO bid [12/75] Ornade (phenylpropanolamine/chlorpheniramine) 1 tab Phenergan-D (pseudoephed/prometh/dextrometh) 5 ml Triaminic Oral Infant Drops (phenylprop/pyrilamine/phenir) 1 dr4op/kg PO bid PO 14-6h PO qid prn. Decongestants oxymetazoline (Afrin) 2 drops/sprays per nostril bid Ephenylephrine (Neo-Synephrine) 1-2 sprays per nostril q3-4h. pseudoephedrine (Sudafed) 60 mg PO q16h. 5ml/dose if 6-12 yo, 2.5 ml/dose if 2-5 yo Time release 120 mg PO bid [0.025,0.05%] [0.125,0.25,0.5,1%] [tabs 30,60,elixir 30 mg/5ml] [120] ----------------------------------------------------------------------------------------------------------------------GI Antidiarrheals loperamide (Imodium) 4 mg PO, may repeat 2 mg prn up to 16 mg/day. Peds (first day) 1 mg tid if 13-20 kg, 2 mg bid if 20-30 kg. 2 mg tid if >30 kg [tab 2, elixir 1 mg/5ml] attapulgite (Kaopectate) 30 ml PO after each loose bowel movement, 15 ml if 6-12 yo, 7.5 ml if 3-6 yo. bismuth subsal (Pepto-Bismol) 2 tabs or 30 ml PO q1h up to 8 doses/24 h. Peds: (per dose) 10 ml if 6-9 yo, 5 ml if 3-6 yo [tab 262, susp 262 & 524 per 15ml] Donnagel (kaolin/pectin/hyoscyamine/atropine/scopolamine) 30ml PO initially, then 15ml PO q3h prn. Lomotil (diphenoxylate 2.5 mg + atropine 0.025 mg per tab or 5ml) 2 tabs or 10ml PO qid. Antiemetics promethazine Peds: metoclopramide prochlorperazine Peds: trimethobemzamide Peds: 100-200 dimenhydrinate scopolamine (Phenergan) 25-50 mg PO/IM/PR q4-6h. 1 mg/kg/dose [12.5,25,50, syrup 5.25 & 25 mg/5ml, supp 12.5,25,50] (Reglan) 10 mg PO/IM/IV 1 h ac and qhs [tabs 5,10, elixir 5 mg/5ml] (Compazine) 5-10 mg PO/IM tid/qid [tabs 5,10,25, elixir 5 mg/5ml] 0.13 mg/kg/dose 25 mg PR q12h [supp 2.5,5,25] (Tigan) 250 mg PO tid/qid, 200 mg IM/PR 16-8h. mg/dose if 30-90 lbs. [tabs 100,250,supp 100,200] (Dramamine) 50 mg PO/IM/IV q4h [50] (Transderm Scop) one patch (0.5 mg) behind ear. Lasts up to three days [Box of 4] Dyspepsia / Antacid / Anti-ulcer omeprazole (Prilosec) cimetidine (Tagamet) famotidine ranitidine (Pepcid) (Zantac) nizatidine (Axid) aluminum hydroxide (Alternagel, Amphojel) calcium carbonate (Tums) 20 mg PO qd [20] 300 mg IV/IM/PO q6h, 400 mg PO bid, or 400-800 mg PO qhs. Continuous IV infusion 37.5 mg/h [200,300,400,800 liquid 300 mg/5ml] 20 mg IV q12h. 20-40 mg PO qhs [20,40, susp 40 mg/5ml] 50 mg IV q6-8h, or continuous infusion 6.25 mg/h. 150 mg PO bid or 300 qhs [150,300, syrup 75 mg/5ml] 150-300 mg PO qhs [150,300] 600 mg or 5 500 ml PO q4h. mg PO prn [300,600, susp 320 & 600mg/5ml] Constipat [500,750, susp 1000 mg/5ml] Maalox Mylanta (alumin & mag hydrox) one tab or 15-30 ml PO prn. (aluminum & magnesium hydrox) one tab or 15-30 ml PO prn. sucralfate Donnatal simethicone Infant drops magaldrate (Carafate) 1 g PO 1h before meals and qhs [1g] (phenobarb/atrop/hyoscy/scop) 1-2 tabs or 5-10 ml PO tid/qid (Mylicon, Gas-x) 40-125 mg PO qid [50,80,125] 0.3 ml PO qid prn (Riopan) 5-10 ml PO prn [480, susp 540 mg/5ml]. Riopan Plus has added simethicone (Cytotec) 100-200 ug PO qid [200 ug] abortifacient misoprostol Laxatives bisacodyl Correctol docusate Na lactulose (Dulcolax) 10 (docu/phenlph)1-2 (Colace) 100 (Chronulac) 30 mg tabs mg ml PO/PR prn [tab 5, supp 10] PO qhs, 1 tab if 6-12 yo PO qd/bid [50,100,250, liquid 20,50 mg/5ml] glycer. one suppos. PR prn PO qhs for constip, 30-45ml PO tid/qid for hepatic enceph. [10 g/15ml] magnesium citrate 4 ml/kg up to 300 ml PO magnesium hydrox (Milk of Mag) 5-15 ml PO prn methylcellulose psyllium senna (Citrucel) (Metamucil) (Fiberall) (Senokot) mineral oil Peds phenolphthalein (Ex-Lax) polyethyl glycol (GoLytely) (CoLyte) sodium biphosph (Fleet enema) sorbitol Maalox Plus has added simethicone Mylanta II has added simethicone [tab 325, liquid 390 mg/5ml] 1 tablespoon in water qd/bid/tid 1 tsp 10-15 ml PO qd/bid/tid PO qhs 5-30 ml PO qhs. 5-20 ml/dose 50-90 mg PO qhs [90] 4 liters PO for complete bowel evacuation. Or 250 ml per NG q15 min for 4h one enema PR prn. [118ml] 2ml/kg up to 50 ml of 70% sol'n PO Other GI agents Anusol ointment or supp bid/tid prn chenodiol (Chenix) 250-500 mg PO bid [250\ pancrelipase (Pancrease) 1-3 tabs PO with meals sulfasalazine (Azulfidine) 500-1000 mg PO qid [500,250 mg/5ml] ursodiol (Actigall) 300 mg PO bid/tid [300] vasopressin (Pitressin, ADH) GI bleeding 100 units in 250 ml D5W (0.4 u/ml) IV at 6-24 u/h (15-60 ml/h) witch hazel (Tucks) pads tid/qid HEMATOLOGY dipyridamole (Persantine) 50-75 mg PO tid/qid [25,50,75] ethrypoietin (Epogen) 50-100 units/kg IV/SC 3 times/week factor VII, factor IX dosage varies ferrous sulfate fresh frozen plasma heparin Load pentoxifylline (Trental) protamine warfarin (Coumadin) 325 mg or 5-10ml PO tid [tabs 250,300,325, elixir 220 mg/5ml] Dosage varies 5000 units IV, infusion 10,000 units in 100 ml D5W (100 units/ml) at 800-1000 units/h (8-10 ml/h) Titrate to PTT. DVT prophylaxis 500 units SC q8-12h 400 mg PO tid [400] 10-50 mg IV over 3-10 min. 1 mg antagonizes approximately 100 units heparin 2-10 mg PO/IM qd [1,2,2.5,5,7.5,10] ----------------------------------------------------------------------------------------------------------------------NEUROLOGICAL Anticonvulsants carbamazepine (Tegretol) 200-600 mg PO bid [tabs 100,200, susp 100/5ml] Aplastic anemia clonazepan (Klonopin) 0.5 mg PO tid [0.5,1,2] ethosuximide (Zarontin) 250 mg PO qd if 3-6 yo, 500-1000 mg PO qd if >6 yo [tab 250, elixir 250 mg/5ml] primidone (Mysoline) 100-125 mg PO qhs [tabs 50,250, liquid 250 mg/5ml] Metabolized to phenobarbital valproic acid (Depakene) 15 mg/kg up to 1000-3000 mg PO divided bid. [tab 250, syrup 250 mg/5ml] Hepatic toxicity. diazepam (Valium) 0.2-0.4 mg/kg up to 5-10 mg IV, or 0.3-0.5 mg/kg PR phenobarbital Load 15-20 mg/kg up to 300-800 mg IV at 25-50 mg/min. Maintenance 60 mg Po bid/tid, peds 3-5 mg/kg/day [tabs 8,16,30,32,60,65,100, elixir 15 & 20 mg/5ml] phenytoin (Dilantin) load 50 mg/min IV to total 15-20 mg/kg or 1000 mg. Mix in NS, precipitates in D5W. 5 mg/kg or 300 mg PO qd or divided tid. [tabs 30,50,100, elixir 30 & 125 mg/5ml] nml range (10-20) Migraine dihydroergotamine (DHE 45) 1 mg IV/IM, repeat in 1h prn ergotamine (Ergostat) 2 mg SL, may repeat q 30 min x2 [2] Parkinsonian agents amantadine benztropine mesylate levodopa selegiline Sinemet trihexyphenidyl Other neurological dexamethasone meningitis edrophonium meclizine methylprednisolone neostigmine nimodipine (Symmetrel) (Dogentin) 100 mg 1-2 mg 250-500 mg (Eldepryl) 5 mg (carbidopa/levodopa) 1 tab (Artane) 1-5 mg PO bid IM/PO qd/bid PO bid PO bid PO bid PO qd [tab 100, syrup 50mg/5ml] [0.5,1,2] [100,250,500] [5] [50/200] [tabs 2,5, elixir 2 mg/5ml] agents (Decadron) Load 10-20 mg IV, maintenance 4 mg 16h for (Tensilon) (Antivert) (SoluMedrol) (Prostigmin) (Nimotop) evaluation of myasth gravis -2mg test IV, then 8mg more after 45sec. Duration 5-10 min. 25 mg PO q6h prn [12.5,25,50] Spinal cord injury 30 mg/kg IV bolus followed by 5.4 mg/kg/h infusion 0.5 mg IM/SC 15-375 mg/d PO divided [15] 60 mg PO q4h [30] cerebral edema. 0.15 mg/kg IV for pediatric OBSTETRICS magnesium SO4 1-4 g of 10-20% sol'n IV over 2-4 min for eclamp, drip 5g in 250ml D5@ (20 mg/ml) at 1 g/h (50 ml/h), titrate to reflexes oxytocin (Pitocin) 10 units IM after placental delivery. Postpartum hemorrhage 10-40 units in 1000 ml NS IV RHO immune globulin (RhoGAM) 1 vial IM within 72h if mother Rh neg ritodrine (Yutopar) 150 mg in 500 ml D5W (0.3 mg/ml) IV at 0.1-0.35 mg/min (24-83 ml/h) 10-20 mg PO 14-6h prn [10] ----------------------------------------------------------------------------------------------------------------------OPHTHALMOLOGY Antimicrobial agents bacitracin ointment q3-4h chloramphenicol (Chloromycetin) 1% ointment q3-4h ciprofloxacin (Ciloxan) 0.35% drops q1-6h Neosporin (bacit/neomy/polymyxin) ointment q3-4h, drops q1-6h Polysporin (bacitracin+polymyxin) ointment q3-4h Corticosteroids dexamethasone prednisolone artificial tears atropine phenylephrine pilocarpine timolol (Decadron) (Pred Forte) (Tears Plus) (Isopto atropine) (Neo-Synephrine) (Pilocar) (Timoptic) Dosage varies. [0.1% drops, 0.05% ointment] Dosage varies [1% drops] 1-2 drops prn 1-2 drops solution, cyclopelgia and mydriasis 7-14d [0.5,1,2,3%] 1 drop solution, mydriasis may persis up to 3h, no cycloplegia [2.5,10%] 1-2 drops tid/qid [0.25,0.5,1,2,3,4,5,6,8,10%] 1 drop bid [0.25,0.5%] Antihistamines Naphcon A 2 drops both eyes QID PSYCHIATRIC Antidepressants SSRIs bupropion fluoxetine sertraline Tricyclics amitriptyline nortriptyline desipramine clomipramine imipramine (Wellbutrin) 100 (Prozac) 20 (Zoloft) 50 mg PO bid/tid mg PO qd mg PO qd (Elavil) (Aventyl) (Pamelor) (Norpramin) (Anafranil) (Tofranil) mg mg mg mg [75,100] Seizures. [tab 20, liquid 20 mg/5ml] [50,100] initially 25 mg PO tid or 75 mg Po qhs [10,25,50,75,100,150] 25 25-200 25-100 50-150 PO PO PO PO tid/qid qhs qd qhs [tabs 10,25,50,75, solution 10 mg/5ml) [10,25,50,75,100,150] [25,50,75] [10,25,50] Other trazodone MAOIs phenelzine Antipsychotics chlorpromazine clozapine fluphenazine haloperidol (Desyrel) 50-100 mg PO tid [50,100,150,300] (Nardil) 15 [15] mg PO tid 400-600 25-50 1-5 2-5 1-5 lithium carbonate (Lithane) 300 molindone (Moban) 5-25 perphenazine (Trilafon) 5 4-8 pimozide (Orap) 1-2 thioridazine (Mellaril) 50-200 thiothixene (Navane) 4 2-5 trifluroperazine (Stelazine) 1-2 Benzodiazepines midazolam oxazepam alprazolam lorazepam chlordiazepoxide for ethanol diazepam clorazepate flurazepam temazepam triazolam (Thorazine) (Clozaril) (Prolixin) (Haldol) (Versed) (Serax) (Xanax) (Ativan) (Librium) withdrawl (Valium) 10-15 0.25-0.5 0.5-2 25-100 5-25 2.5-5 2-10 (Tranxene) 7.5-15 (Dalmane) 15-30 (Restoril) 15-30 (Halcion) 0.125-0.5 mg mg mg mg mg mg mg mg mg mg mg mg mg mg PO/IM PO PO/IM IM PO PO PO IM PO PO PO IM PO IM bid/tid/qid qd q6-8h. q4-8h prn tid tid tid/qid q6h. tid qd tid q6-12h. qid q4-6h. [tabs 10,25,50,100,200, supp 25,100,syrup 10 mg/5ml] [25,100] Agranulocytosis [tabs 1,2.5,5,10, elixir 2.5 mg/5ml] [tabs 0.5,1,2,5,10,20, liquid 2 mg/ml] [tabs 150,300,600, syrup 300 mg/5ml] [5,10,25,50,100, liq 20mg/ml] [tabs 2,4,8,16, liquid 16 mg/5ml] [2] [tabs 10,15,25,50,100,150,200, suspension 25 & 100 mg/5ml] [tabs 1,2,5,10,20, liquid 5 mg/ml] 2-5mg PO bid [tabs 1,2,5,10, liquid 10 mg/ml] ½-life 2.5h 0.07mg/kg mg PO tid/qid. Half-life 5-15h mg PO tid. Half-life 12h mg IV/IM/PO q6-8h. Half-life 8-20h mg IV/IM q2-4h Half-life 24h mg PO tid/qid mg increments IV up to 0.2 mg/kg. mg PO tid/qid. Half-life 20-50h mg PO qhs/bid Half-life 60h mg PO qhs. Half-life 70-90h mg PO qhs. Half-life 8-25h mg PO qhs. Half-life 2-3h IM. 1mg IV q2-3min to 0.15 mg/kg. Dur 1-4h. [10,15,30] [0.25,0.5,1,2] [0.5,1,2] [5,10,25] [tabs 2,5,10, sol'n 5 mg/5ml] [3.75,7.5,15] [15,30] [15,30] [0.125,0.25] Sedatives / Hypnotics / Anxiolytics buspirone (BuSpar) 5-10 mg PO tid [5,10] ethchlorvynol (Placidyl) 500 mg PO qhs [200,500,750] hydroxyzine (Atarax) (Vistaril) 0.5 mg/kg up to 25-50 mg PO/IM q4-6h prn. [tabs 10,25,50,100, susp 10 & 25 mg/5ml] meprobamate (Equanil) (Miltown) 400 mg PO tid/qid [200,400,600] pentobarbital (Nembutal) 30-150 mg PO/IV/IM/PR tid/qid. Peds: 2-6 mg/kg/day [tabs 50,100, supp 30,60,120,200, elixir 20 mg/5ml] Stimulants / Anorexiants methylphenidate (Ritalin) 5-10 mg PO bid/tid [5,10,20] pemoline (Cylert) 37.5 mg PO qd [18.75,37.5,75] ----------------------------------------------------------------------------------------------------------------------PULMONARY acetylcysteine (Mucomyst) 6-10 ml of 10% or 3-5 ml of 20% solution nebulized q6-8h. Acetaminophen toxicity: Load 140 mg/kg of 20% sol'n PO or per NG, then 70 mg/kg 14h x 17 doses. May be mixed in water or soda. Mucolytic albuterol (Ventolin) (Proventil)0.5 ml of 0.5% sol'n (2.5 mg) nebulized q6h Inhaler 2 puffs q4-6h. 2-4 mg PO tid/qid. Peds: 2-6 yo 0.1 mg/kg up to 2 mg PO tid [tabs 2,4, syrup 2 mg/5ml] aminophylline 200 mg PO tid/qid [100,200] Load 6 mg/kg IV over20-30 minutes, drip 1g in 250 ml D5W (4mg/ml) at 0.5-0.7 mg/kg/h. 70 kg: 44 mg/h (11 ml/h). Peds beclomethasone 1 mg/kg/h. (Vanceril) (Beclovent)2 cromolyn sodium epinephrine flunisolide ipratropium metaproterenol puffs tid/qid. (Intal) 20 mg inhaled qid. 200 mg PO qid [100] 0.01 ml/kg up to 0.3-0.5 ml (0.3-0.5 mg) of 1:1,000 solution SC. (AeroBid) 2 puffs bid (Atrovent) 2 puffs qid (Alupent) 0.01 ml/kg up to 0.3 ml 5% sol'n nebulized q4h. Inhaler 2-3 pubbs 13-4h. Oral 20 mg PO tid/qid. 10 mg/dose if 6-9 yo, 2 mg/kg/day if <6 yo. [tabs 10,20, syrup 10 mg/5ml] terbutaline (Brethine) 0.25 mg SC. Inhaler 2 puffs q4-6h. 2.5-5 mg PO tid. Not recommended in patients uner 12 years. [2.5,5] theophylline, sust rel. (Theo-Dur) (Slo-bid) 100-300 mg PO bid [tabs 100,200,300,450] Pediatric sprinkles (Theo-Dur) 10 mg/kg/dose PO bid [50,75,125,200] triamcinolone acetonide (Azmacort) 2 MISCELLANEOUS azathioprine charcoal deferoxamine (Imuran) (Desferal) puffs tid/qid Dosage varies [50] 0.5-1.0 g/kg up to 30-90 g PO. Can repeat q4h. 50 mg/kg up to 500-1000 mg IM. Consider IV infusion up to 15 mg/kg/h. iron toxicity. dimercaprol (BAL) arsenic, mercury, gold, lead toxicity. Dose varies. disulfiram (Antabuse) 250-500 mg PO qd [250,500] edetate disodium (EDTA) lead toxicity. Dosage varies. ethanol: methanol, ethylene glycol toxicity. 1000 mg/kg (10 ml/kg) of 10% ethanol (100 mg/ml) IV over 1-2h then 100 mg/kg/h (10 ml/kg/h) to keep ethanol level approximately 100 mg/dl ipecac syrup infant 5-10 ml PO, child 15 ml, adult 30 ml nicotine gum (Nicorette) 10-20 pieces/day prn [2 mg, 4 mg, 96 pieces/box) nicotine patches one patch (14-22 mg) qd, taper after 6 weeks. [Habitrol, Nicoderm 7,14,21, ProStep 11,22] penicillamine (Cuprimine) Dosage varies [125,250]