NES/ASAP Pharmacy Vocational Training Scheme
Specialist module
Infection and Antimicrobial Stewardship
Stage 3
Resources 11th May 2014 v1.8
1
Please note that, with the exception of text books, the majority of resources within these lists will be available free of charge. Those
which require either free registration or require a fee to be paid are annotated accordingly.
It is assumed that all participants will have registered with The Knowledge Network (TKN) and will have an Athens Password. Some of the
URL links for such resources will link you direct to the article once you have entered your Athens password - if this fails, you should be
able to access the article yourself via TKN.
Articles from the Journal of Antimicrobial Chemotherapy are available on the BSAC website or via TKN
There are a few resources listed which are on the YouTube platform and may not be accessible from NHS premises. These may require to
be viewed from home or on a personal electronic device.
For webinars and videos the approximate running time is given in brackets after the name of the presentation
We would welcome your feedback - please contact NES Pharmacy if you have any comments about these resources or if you have trouble
accessing any of the key resources.
2
Contents
Page number
Bibliography
Suggested texts - to be used for background knowledge as available locally for
appropriate elements
5
Element 1 Introduction to Antimicrobial Stewardship Core resources
7
Element 2 Essential microbiology, resistance and basic immune function
11
Element 3 Antimicrobial agents by therapeutic class
15
Element 4 Healthcare Acquired Infection (HAI)
17
Element 5 Sepsis Diagnosis and Management
21
Element 6 Acute respiratory tract infection incorporating pneumonia and
COPD
Element 7 - Urinary tract infection (UTI)
23
Element 8 Skin and soft tissue infection (SSTI)
29
Element 9 Surgical infection & prophylaxis
33
Element 10 Pharmacokinetics (PK) pharmacodynamics (PD) and
therapeutic drug monitoring (TDM)
35
Element 11 Data analysis and presentation Incorporating interpretation of
audit data
Element 12 Meningitis and CNS Infection
39
Element 13 Endocarditis and Cardiovascular Infection
44
Element 14 Bone & Joint Infections
46
26
41
3
Element 15 Gastrointestinal (GI) infections
48
Element 16 - Antibiotics used in pregnancy, neonates and paediatrics
51
Element 17 Sexually transmitted infection (STI), human immunodeficiency
virus (HIV) & other blood borne virus (BBV)
56
Element 18 Tropical infectious diseases
62
Element 19 Chronic respiratory tract infections - tuberculosis (TB), cystic
fibrosis (CF) and non-CF bronchiectasis
65
Element 20 Fungal infections
68
Element 21 Outpatient parenteral antimicrobial therapy (OPAT)
70
4
Bibliography
Suggested texts - to be used for background knowledge as available locally for appropriate elements
Resource
ID
Name of resource
210 Antimicrobial Chemotherapy 6th Ed 2012 if available
219 Sanford Guide 2013 if available
Resource owner
Oxford University
Press
Antimicrobial
Therapy Inc
Presenter
/Author
Finch RG
Gilbert et al
(Eds)
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.sanfordguide.com/
296 Manual of Clinical microbiology 9th Ed 2007 (on TKN)
ASM press
299 Reese & Betts' practical approach to infectious diseases Lippincott Williams
5th Ed 2003 (on TKN)
and Wilkins
Murray PR et al https://www.123library.org/bookdetails/?id=2814
Betts RF et al
http://www.knowledge.scot.nhs.uk/home/library/books/
booksresults.aspx?q=ctitle:(string(%22reese%22%2c+mode%3d
%22and%22)+and+string(%22betts%22%2c+mode%3d%2
2and%22))&pm=fql&title=reese+and+betts&srt=rptitle10
0sub50bod20
329 Kucers' The Use of Antibiotics 6th Ed if available
ASM Press & Hodder Grayson ML
Arnold
330 Principles and Practice of Infectious Diseases 7th Ed if
Elsevier Churchill
Mandell GL et al
available
Livingstone
292 Notes on medical Microbiology 4th Ed 2002 if available Churchill Livingstone Timbury MC et
al
293 Clinical bacteriology 2003 if available
Manson Publishing Struthers JK et
al
384 Infection and Immunity 3rd Ed 2008 or 4th Ed 2013 if
Oxford University
Playfair J
available
Press
Bancroft G
385 Basic & Clinical Immunology if available
Churchill Livingstone Peakman M
Vergani D
374 British National Formulary (BNF)
BMJ/RPS
http://www.medicinescomplete.com/about/index.htm
375 British National Formulary for Children (BNF-C)
BMJ/RPS
http://www.medicinescomplete.com/about/index.htm
442 Stockley's Drug Interactions (Via TKN)
Medicines Complete
http://www.medicinescomplete.com/mc/stockley/curren
5
Suggested texts - to be used for background knowledge as available locally for appropriate elements
Resource
ID
Name of resource
301 ABC of Sepsis 2010 if available - comes highly
recommended
378 Infectious Diseases of the Fetus and Newborn (7th
Edition) if available
479 Medications and Mothers' Milk 2012 if available
440 Neonatal Formulary (6th ED) with updates 2011 if
available
376 Drugs in Pregnancy and Lactation: A Reference Guide to
Fetal and Neonatal Risk 9th ed (via TKN)
302 ABC of HIV and AIDS 6th Ed 2012 if available (comes
highly recommended but would need to be purchased)
346 Oxford Handbook of Tropical Medicine 2005 (New
edition published in 2014) if available
430 Manson's Tropical Diseases 23rd Ed 2013 if available
429 Hunter's Tropical Medicine and Emerging Infectious
Disease: Expert Consult -2013 Online and Print, 9e if
available
501 Oxford Textbook of Medicine 2003 (via TKN)
513 Applied Pharmacokinetics & Pharmacodynamics:
Principles of Therapeutic Drug Monitoring 2006
Resource owner
BMJ Books Wiley
Blackwell
Elsevier
Hale Publishing
Wiley
Presenter
/Author
URL link direct to resource
t/
Date Resource
Accessed/
Comments
Daniels R
Remington J et
al
Hale T
Hey E (Editor)
http://www.amazon.co.uk/dp/1416064001/ref=rdr_ext_t
mb
http://www.neonatalformulary.com/default.asp
Lippincott Williams & Briggs G
http://www.knowledge.scot.nhs.uk
Wilkins
BMJ Books Wiley
Alder MW
Blackwell
Oxford Press
Eddleston M et http://www.talcuk.org/books/oxford-handbook-ofal
tropical-medicine-3rd-edition.htm
Elsevier
Farrar J et al
(Ed)
Elsevier
Magill AJ et al
(ED)
Oxford University
Warrell D Ed
http://www.knowledge.scot.nhs.uk/
Press
Lippincott Williams & Burton ME et al
Wilkins
(Editors)
6
Resources for Element 1 Introduction to Antimicrobial Stewardship
CORE RESOURCES
Element 1 - INTRODUCTION TO ANTIMICROBIAL STEWARDSHIP - CORE RESOURCES
Resource
ID
Name of resource
Resource owner
SAPG & SCOTTISH GOVERNMENT REFERENCES
Scottish Antimicrobial Prescribers Group (SAPG) website Scottish Medicines
Consortium
8 Training on Use of Antimicrobials in Clinical Practice
NES
(SAPG) (60 mins)
(Additional CPD section not compulsory)
Presenter
/Author
SAPG
HIS/SAPG
107 Good Practice Recommendations for Antimicrobial Use SAPG
in Frail Elderly Patients in NHS Scotland
SAPG
121 SAPG Good Practice Recommendations for Hospital
Antimicrobial Stewardship in NHS Scotland
SAPG
SAPG
138 Scot MARAP 2008 (Due for update in 2013/14)
Scottish Government
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.scottishmedicines.org.uk/SAPG/Scottish_Ant
imicrobial_Prescribing_Group__SAPG_
http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associatedinfections/training-resources/antimicrobials-in-clinicalpractice.aspx
http://www.scottishmedicines.org.uk/files/sapg/SAPG_R
ecommendations_for_antibiotic_use_in_frail_elderly__February_2013.pdf
http://www.scottishmedicines.org.uk/files/sapg/Good_pr
actice_recommendations_for_hospital_antimicrobial_ste
wardship_2012.pdf
http://www.scotland.gov.uk/Publications/2008/03/1215
3030/0
LOCAL HEALTH BOARD REFERENCES
Local health board website or intranet
OTHER ANTIMICROBIAL STEWARDSHIP REFERENCES
140 Guidelines for Developing an Institutional Program to
Enhance Antimicrobial Stewardship
390 Antimicrobial Stewardship Start Smart then Focus
Clinical Infectious
Diseases 2007;
44:159–77
Department of
Health
Dellit TH et al
http://www.idsociety.org/Antimicrobial_Agents/#Antimic
robial Stewardship
https://www.gov.uk/government/publications/antimicro
bial-stewardship-start-smart-then-focus
SCOTTISH PATIENT SAFETY PROGRAMME REFERENCES
7
Element 1 - INTRODUCTION TO ANTIMICROBIAL STEWARDSHIP - CORE RESOURCES
Resource
ID
Name of resource
489 Scottish Patient Safety Programme Website
Resource owner
SPSP
Presenter
/Author
Health
Improvement
Scotland
URL link direct to resource
http://www.scottishpatientsafetyprogramme.scot.nhs.uk
/programme
Date Resource
Accessed/
Comments
SUPPLEMENTARY RESOURCES
Element 1 INTRODUCTION TO ANTIMICROBIAL STEWARDSHIP - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
SAPG & SCOTTISH GOVERNMENT REFERENCES
118 SAPG Good Practice Guidance on Ratification of
Antimicrobial Policies
114 Recommendations for Good Antimicrobial Practice in
Acute Hospitals 2005
110 (SAPG): development and impact of the Scottish
National Antimicrobial Stewardship Programme (via
TKN)
113 Antimicrobial stewardship in Scotland: impact of a
national programme
OTHER ANTIMICROBIAL STEWARDSHIP REFERENCES
19 Antimicrobials & Infection Management (10 hours to
complete full module - can dip in for specific subjects)
Resource owner
Presenter
/Author
SAPG
SAPG
NES
NI Centre for
Pharmacy
Learning &
Development
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.scottishmedicines.org.uk/files/GOOD_PRACT
ICE_GUIDANCE_ON_RATIFICATION_OF_ANTIMICROBIAL_
POLICIES.pdf
Scottish Government
http://www.scotland.gov.uk/Resource/Doc/69582/00170
99.pdf
Int J Antimicrob
Nathwani D et al http://www.sciencedirect.com/science/article/pii/S09248
Agents 2011; 38(1):
57911001026
16-26
Antimicrob Res Inf
Nathwani D et al http://www.aricjournal.com/content/1/1/7
Cont 2012, 1:7
109 From intermittent antibiotic point prevalence surveys to Antimicrob Res Inf
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/resources-by-topic/infectiousdiseases/antibiotics/antimicrobials-and-infectionmanagement.aspx
Malcolm W et al http://www.aricjournal.com/content/2/1/3
8
Element 1 INTRODUCTION TO ANTIMICROBIAL STEWARDSHIP - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
Resource owner
quality improvement: experience in Scottish hospitals
117 Antimicrobial Stewardship in Australian Hospitals
Cont 2013;2:3
ACSQH
230 Annual Report of the Chief Medical Officer 2011:
Volume Two
Department of
Health
This publication provides a comprehensive overview of
the threat of antimicrobial resistance and infectious
diseases.
231 The missing care bundle: antibiotic prescribing in
hospitals (via TKN or Athens login)
187 Interventions to improve antibiotic prescribing practices
for hospital inpatients (via TKN or Athens login)
305 Effectiveness of the interventions in antimicrobial
stewardship: What works? Updated Cochrane
systematic review and systematic review methodology
(via TKN) (60 mins)
306 Understanding the Determinants of Antimicrobial
Prescribing Within Hospitals: The Role of “Prescribing
Etiquette”
Presenter
/Author
URL link direct to resource
Duguid M
Cruikshank M
http://www.safetyandquality.gov.au/publications/antimi
crobial-stewardship/
Davies S
https://www.gov.uk/government/publications/chiefmedical-officer-annual-report-volume-2
Int J Ant Agents
Cooke FJ et al
2007; 30:25-29
CDSR 2013, Issue 4. Davey P et al
Art. No.: CD003543.
ASAP Shared Space Davey P
http://www.ijaaonline.com/article/S09248579(07)00146-X/abstract
http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD
003543.pub3/abstract
http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Upl
oads/2013/Jun/20130614155109_Cochrane%20Webinar
%20PDavey.pdf
Clin Infect Dis. (2013) Charani E et al
57 (2): 188-196
http://cid.oxfordjournals.org/content/57/2/188.long
Date Resource
Accessed/
Comments
9
Resources for Element 2 Essential microbiology, resistance and basic immune function
CORE RESOURCES
Element 2 - ESSENTIAL PHARMACEUTICAL MICROBIOLOGY, BACTERIAL RESISTANCE & BASIC IMMUNE FUNCTION - CORE RESOURCES
Resource
ID
Name of resource
MICROBIOLOGY & LAB REFERENCES
1 Bugs and Drugs Part 1 (30 mins)
15 Basic Microbiology (2 hours)
337 A Microbiologists View of Bugs & Drugs for ASAP (50
mins)
Resource owner
Presenter
/Author
NES
Kieran Hand
NES
NES
436 An insight into the National Reference Laboratory (47 NES
mins)
BACTERIAL RESISTANCE REFERENCES
12 Bacterial Resistance (2 hours)
13 Multi-resistant Gram Negative Bacilli (MRGNB) (15
mins)
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/webinars-and-virtual-patientscenarios/webcasts/bugs-and-drugs-part-1.aspx
NES/LearnPro http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associated-infections/onlineshort-courses/basic-microbiology.aspx
Alistair Leonard http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/resources-by-topic/infectiousdiseases/antibiotics/a-microbiologists-view-of-bugs-anddrugs-for-asap.aspx
John Coia
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/resources-by-topic/infectiousdiseases/antibiotics/an-insight-into-the-nationalreference-laboratories-for-asap.aspx
NES
NES/LearnPro
NES
NES/LearnPro
http://www.nes.scot.nhs.uk/education-and-training/by- Sept 2015
theme-initiative/healthcare-associated-infections/online- Not available
short-courses/bacterial-resistance.aspx
HAI withdrawn
http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associated-infections/onlineshort-courses/multi-resistant-gram-negative-bacilli(mrgnb).aspx
10
Element 2 - ESSENTIAL PHARMACEUTICAL MICROBIOLOGY, BACTERIAL RESISTANCE & BASIC IMMUNE FUNCTION - CORE RESOURCES
Resource
ID
Name of resource
138 Scot MARAP 2008 due for update in 2013/14
BASIC IMMUNE FUNCTION REFERENCES
386 Clinical Guidelines for Immunoglobulin Use 2nd Ed
update March 2012
101 Your Immune System 101: Introduction to Clinical
Immunology (YouTube - skip adverts) (90 mins)
102 Basic Immunology - Nuts and Bolts of the Immune
System (YouTube - skip adverts) (90 mins)
Resource owner
Presenter
/Author
URL link direct to resource
Scottish Government
http://www.scotland.gov.uk/Publications/2008/03/1215
3030/0
Department of
Health
UCSF
http://www.nsd.scot.nhs.uk/Documents/clinimmumoMa
rch12.pdf
http://www.youtube.com/watch?v=_oI0jVN4TTI&feature
=player_detailpage
http://www.youtube.com/watch?feature=player_detailp
age&v=mFNxXfwlP3A
UCSF
Dr Katherine
Gundling
Dr Anthony De
Franco
Date Resource
Accessed/
Comments
SUPPLEMENTARY RESOURCES
Element 2 - ESSENTIAL PHARMACEUTICAL MICROBIOLOGY, BACTERIAL RESISTANCE & BASIC IMMUNE FUNCTION - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
Resource owner
MICROBIOLOGY & LAB REFERENCES
466 BSAC Methods for Antimicrobial Susceptibility Testing BSAC
Version 12 May 2013
207 Guidelines on the laboratory diagnosis and
J Antimicrob
susceptibility testing of MRSA
Chemother 2005; 56:
1000 - 1018
221 Guidance on the diagnosis and management of PVL- HPA/DoH
associated Staphylococcus aureas infection 2008
52 BSAC antimicrobial susceptibility testing – from
BSAC
Stokes to European harmonization to world? (20
mins)
Presenter
/Author
URL link direct to resource
Date Resource
Accessed/ Comments
BSAC
http://bsacstage.pharma-mix.com////wpcontent/uploads/2012/02/Version-12-Apr-2013_final.pdf
Brown DFJ et al http://jac.oxfordjournals.org/content/56/6/1000.full.pdf
HPA/DoH
http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1
218699411960
Dr Derek Brown http://bsac.org.uk/events/past-events-2011/springmeeting-agm-2011/spring-meeting-2011/
BACTERIAL RESISTANCE REFERENCES
11
Element 2 - ESSENTIAL PHARMACEUTICAL MICROBIOLOGY, BACTERIAL RESISTANCE & BASIC IMMUNE FUNCTION - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
276 Rapid evolution and spread of carbapenemases
among Enterobacteriaceae in Europe (TKN or Athens
login)
278 Has the era of untreatable infections arrived?
7 Patterns of Antimicrobial Use and Resistance in
Scotland(MSc) (56 mins)
20 Avoiding Antibiotic Resistance: the role of the
pharmacy team (NB quite old resource, may soon be
replaced) (6 hours to complete whole module - can
dip in for specific subjects)
Resource owner
Presenter
/Author
Canton R et al
Eur Clin Microbiol
Infect 2012;18: 413–
431
J Antimicrob
Livermore DM
Chemother 2009;64
Suppl1:i29-i36
NES
William
Malcolm
NES
NES Portal
44 What is happening now? Epidemiology of resistance
(20 mins)
45 Carbapenemases in Practice (29 mins)
BSAC
46 Neisseria gonorrhea – the first untreatable infection
(20 mins)
48 VRE – one difficult Gram positive after another.
Treatment options for severe infections (26 mins)
49 Optimisation of combination therapy for treatment of
Pseudomonas aeruginosa (10 mins)
51 New Uses for Old Agents (25 mins)
BSAC
BSAC
BSAC
BSAC
BSAC
60 Antibiotic cycling - a worthwhile weapon against gram BSAC
negative resistance? (30 mins)
111 Overview of strategies for overcoming the challenge Expert Rev. Clin.
of antimicrobial resistance
Pharmacol. 3(5),
667–686 (2010)
URL link direct to resource
Date Resource
Accessed/ Comments
http://onlinelibrary.wiley.com/doi/10.1111/j.14690691.2012.03821.x/abstract
http://jac.oxfordjournals.org/content/64/suppl_1/i29.full
.pdf+html
http://www.video3uk.com/login.aspx
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/resources-by-topic/infectiousdiseases/antibiotics/avoiding-antibiotic-resistancetherole-of-the-pharmacy-team.aspx
Prof Neil
http://bsac.org.uk/events/past-events-2013/bsac-springWoodford
meeting-2013/bsac-spring-meeting-agm-2013-videos/
Dr Andrew
http://bsac.org.uk/events/past-events-2013/bsac-springDodgson
meeting-2013/bsac-spring-meeting-agm-2013-videos/
Prof Catherine http://bsac.org.uk/events/past-events-2013/bsac-springIson
meeting-2013/bsac-spring-meeting-agm-2013-videos/
Dr Nick Brown http://bsac.org.uk/events/past-events-2013/bsac-springmeeting-2013/bsac-spring-meeting-agm-2013-videos/
Dr Alexander
http://bsac.org.uk/events/past-events-2013/bsac-springCochrane
meeting-2013/bsac-spring-meeting-agm-2013-videos/
Dr Kieran Hand http://bsac.org.uk/events/past-events-2013/bsac-springmeeting-2013/bsac-spring-meeting-agm-2013-videos/
Bob Masterton http://www.online-web-presentations.com/BSAC_2010/
Davey P et al
http://www.scottishmedicines.org.uk/files/sapg/Davey_2
010.pdf
12
Element 2 - ESSENTIAL PHARMACEUTICAL MICROBIOLOGY, BACTERIAL RESISTANCE & BASIC IMMUNE FUNCTION - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
Resource owner
209 Effective antibacterials: at what cost? The economics J. Antimicrob.
of antibacterial resistance and its control
Chemother.2012; 66:
1948-1953
212 Risks of extended-spectrum beta-lactamases (via
DTB 2008;46:21-24
TKN/Athens login)
222 The evolving threat of antimicrobial resistance
WHO
223 The Future of antibiotics resistance
271 Antibiotic Prescribing - Reduce and Resist (via TKN)
URL link direct to resource
Date Resource
Accessed/ Comments
http://jac.oxfordjournals.org/content/66/9/1948.full.pdf
http://dtb.bmj.com/content/46/3/21.full
http://whqlibdoc.who.int/publications/2012/9789241503
181_eng.pdf
Spellberg B et al http://www.nejm.org/doi/pdf/10.1056/NEJMp1215093
n engl j med 368;4
nejm.org january 24,
2013
ASAP Shared Space Philip C
275 Susceptibility of Klebsiella pneumoniae Isolates from Antimicrob Agents
Intra-Abdominal Infections and Molecular
Chemother. 2011
Characterization of Ertapenem-Resistant Isolates
55(8): 3917–3921
BASIC IMMUNE FUNCTION REFERENCES
379 Immunisation against infectious disease: the Green
Book
Presenter
/Author
WhiteAR
http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Upl
oads/2010/Sep/20100922142033_quiz%20section%20Re
duce%20and%20resist%20section%202010.pdf
Hawser SP et al http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147618
/
Department of
Health
https://www.gov.uk/government/organisations/publichealth-england/series/immunisation-against-infectiousdisease-the-green-book
384 Infection and Immunity 3rd Ed 2008 or 4th Ed 2013 if Oxford University
Playfair J
available
Press
Bancroft G
385 Basic & Clinical Immunology if available
Churchill Livingstone Peakman M
Vergani D
13
Resources for Element 3 Antimicrobial agents by therapeutic class
CORE RESOURCES
Element 3 - ANTIBIOTICS BY THERAPEUTIC CLASS - CORE RESOURCES
Resource owner
Presenter
/Author
NES
Kieran Hand
443 Electronic Medicines Compendium eMC
219 Sanford Guide 2013 if access available (subscription
or purchase required)
374 British National Formulary (BNF)
Datapharm
Antimicrobial
Therapy Inc
BMJ/RPS
Gilbert et al
(Eds)
ADVERSE DRUG REACTIONS & INTERACTIONS
REFERENCES
442 Stockley's Drug Interactions (via TKN)
Medicines Complete
467 Yellow Card Reporting Website
MHRA
Name of resource
GENERAL CLASSIFICATION OF ANTIBIOTICS
REFERENCES AND LOCAL GUIDELINES
Local Antimicrobial Prescribing Guidelines
2 Bugs and Drugs Part 2 (35 mins)
Resource ID
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.nes.scot.nhs.uk/education-andtraining/by-discipline/pharmacy/about-nespharmacy/educational-resources/webinars-andvirtual-patient-scenarios/webcasts/bugs-and-drugspart-2.aspx
http://www.medicines.org.uk/emc/
http://www.sanfordguide.com/
http://www.medicinescomplete.com/about/index.h
tm
MHRA
http://www.medicinescomplete.com/mc/stockley/c
urrent/
http://yellowcard.mhra.gov.uk/
14
SUPPLEMENTARY RESOURCES
Element 3 - ANTIBIOTICS BY THERAPEUTIC CLASS - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
GENERAL CLASSIFICATION OF ANTIBIOTICS
REFERENCES AND LOCAL GUIDELINES
19 Antimicrobials & Infection Management (10 hours
to complete full module - can dip in for specific
subjects)
Resource owner
NES
125 Management of infection guidance for primary care HPA
HPA
215 Gentamicin ototoxicity: a 23 year selected case
MJA June 2012
series of 103 patients
;196(11) 701-05
217 2005-2006 Field Guide to Antibiotic Therapy
218 Carbapenem Antibiotics for serious infections (via
TKN or Athens login)
220 Johns Hopkins ABX Guide (subscription required some MI centres may subscribe)
441 UKCPA Drug Dosing in Extremes of Body Weight in
Critically Ill Patients 2013
Presenter
/Author
URL link direct to resource
Date Resource
Accessed/ Comments
NI Centre for
Pharmacy
Learning &
Development
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/resources-by-topic/infectiousdiseases/antibiotics/antimicrobials-and-infectionmanagement.aspx
http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1
279888711402
Ahmed RM et al https://www.mja.com.au/journal/2012/196/11/gentami
cin-ototoxicity-23-year-selected-case-series-103patients
http://www.zubnistranky.cz/atb.pdf
Drug Topics Astra
Zeneca
BMJ 2012;344:e3236 Hawkey PM et al http://www.bmj.com/content/344/bmj.e3236
Unbound Medicine
Inc
UKCPA
http://www.hopkinsguides.com/hopkins/ub/index/John
s_Hopkins_ABX_Guide/All_Topics/A
http://www.nes.scot.nhs.uk/media/2536057/vt3_drug_
dosing_ukcpa_doc__for_resources__website__jan_201
4.pdf
15
Resources for Element 4 Healthcare Acquired Infection (HAI)
CORE RESOURCES
Element 4 - HEALTHCARE ASSOCIATED INFECTION (HAI) - CORE RESOURCES
Resource
ID
Name of resource
HAI GENERAL REFERENCES
387 HPS Compendium of Healthcare Associated Infection
Guidance
CDI REFERENCES
3 Bugs and Drugs Part 3 Clostridium difficile associated
disease (CDAD) (15 mins)
Resource owner
Presenter
/Author
Health Protection
Scotland
http://www.hps.scot.nhs.uk/haiic/publicationsdetail.aspx
?id=47911
NES
Kieran Hand
10 Clostridium difficile HIA Learning Tutorial (2 hours)
NES
NES/LearnPro
11 Clostridium difficile HAI Clinical Scenario (60 mins)
NES
NES/LearnPro
327 C Difficile Associated Disease Clinical Vignette (20) (free PAUSE
registration for HCPs) (2 hours)
437 Guidance on Prevention and Control of Clostridium
HPS
difficile Infection (CDI) in Healthcare Settings in
Scotland
388 SMC Advice on fidaxomicin
Scottish Medicines
Consortium
SABs / MRSA REFERENCES
283 Clinical Practice Guidelines for the Diagnosis and
Management of Intravascular Catheter-Related
Infection: 2009 Update by the Infectious Diseases
Clinical Infectious
Diseases
2009;49(1):1-45
URL link direct to resource
Date Resource
Accessed/
Comments
BSAC
HPS
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/webinars-and-virtual-patientscenarios/webcasts/bugs-and-drugs-c-difficile.aspx
http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associated-infections/onlineshort-courses/c-difficile-a-clinical-tutorial.aspx
http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associated-infections/onlineshort-courses.aspx
http://www.pause-online.org.uk
http://www.documents.hps.scot.nhs.uk/abouthps/hpn/clostridium-difficile-infection-guidelines.pdf
https://www.scottishmedicines.org.uk/SMC_Advice/Advi
ce/791_12_fidaxomicin_dificlir/fidaxomicin_Dificlir
Mermel LA et al http://cid.oxfordjournals.org/content/49/1/1.full
16
Element 4 - HEALTHCARE ASSOCIATED INFECTION (HAI) - CORE RESOURCES
Resource owner
Presenter
/Author
URL link direct to resource
PAUSE
BSAC
http://www.pause-online.org.uk
PAUSE
BSAC
http://www.pause-online.org.uk
NES
NES/LearnPro
18 MRSA Clinical Scenario (2 hours)
NES
NES/LearnPro
22 Preventing Catheter Related Bloodstream Infections
(60 mins)
NES
NES/LearnPro
391 Staphyloccus Aureus Bacteraemia Algorithm and
Quality Indicators 2012/13
203 Guidelines (2008) for the prophylaxis and treatment of
methicillin-resistant Staphylococcus aureus (MRSA)
infections in the United Kingdom
SAPG
SAPG
J. Antimicrob.
Chemother., May
2009; 63: 849 - 861
Gould FK et al
http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associated-infections/onlineshort-courses/mrsa-a-clinical-tutorial.aspx
http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associated-infections/onlineshort-courses/mrsa-a-clinical-scenario.aspx
http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associated-infections/onlineshort-courses/preventing-catheter-related-bloodstreaminfections.aspx
http://www.scottishmedicines.org.uk/SAPG/Quality_Imp
rovement/Staph_aureus_bacteraemia
http://jac.oxfordjournals.org/content/63/5/849.full.pdf
Resource
ID
Name of resource
Society of America (note corrigendum)
319 MRSA Treatment Errors Clinical Vignette (12) (free
registration for HCPs) (60 mins)
325 IV Catheter Related Infection Clinical Vignette (18) (free
registration for HCPs) (2 hours)
17 MRSA An Online Tutorial (3 hours)
Date Resource
Accessed/
Comments
17
SUPPLEMENTARY RESOURCES
Element 4 - HEALTHCARE ASSOCIATED INFECTION (HAI) - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
HAI GENERAL REFERENCES
6 Healthcare Associated Infection (MSc)
(free registration required) (45 mins)
389 Scottish Government HAI Task Force
Resource owner
NES
Infect Cont Hoso
Epidem 2010 ; 31 :
431 -455
186 Successful use of feedback to improve antibiotic
JAC (2007) 59 (5):
prescribing and reduce Clostridium difficile infection: a 990-995.
controlled interrupted time series
439 Updated guidance on the management and treatment HPA
of Clostridium difficile infection (English Guidance)
205 Guidelines for UK practice for the diagnosis and
management of (MRSA) infections presenting in the
community
392 Clinical Management of SAB (via TKN / Athens login)
Clinical Infectious
Diseases ; 2011 ; 52 :
1 -38
J. Antimicrob.
Chemother.,2008;
61: 976 - 994.
Lancet Inf Dis
2011;11:208-22
URL link direct to resource
Jacqueline
Sneddon
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/webinars-and-virtual-patientscenarios/webinars.aspx
http://www.scotland.gov.uk/Topics/Health/Services/Prev
enting-Healthcare-Infections/InfectionMonitoring/Taskforce
Cohen SH et al
http://www.idsociety.org/Organism/
Fowler S et al
http://jac.oxfordjournals.org/content/59/5/990.full
HPA
www.hpa.org.uk/webc/HPAwebfile/HPAweb_C/1317138
914904
LIU C et al
http://www.idsociety.org/Organism/
Scottish Government
CDI REFERENCES
150 Clinical Practice Guidelines for Clostridium difficile
Infection in Adults: 2010
SABs MRSA REFERENCES
166 Management of Patients with Infections Caused by
Methicillin-Resistant Staphylococcus Aureus
Presenter
/Author
Date Resource
Accessed/
Comments
Nathwani D et al http://jac.oxfordjournals.org/content/61/5/976.full.pdf
Thwaites GE et
al
http://www.thelancet.com/journals/laninf/article/PIIS14
73-3099(10)70285-1/abstract
18
Element 4 - HEALTHCARE ASSOCIATED INFECTION (HAI) - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
368 MRSA Screening and Suppression - Quick Reference
Guide for Primary Care
Resource owner
HPA
Presenter
/Author
URL link direct to resource
http://www.hpa.org.uk/Topics/InfectiousDiseases/Infecti
onsAZ/PrimaryCareGuidance/
Date Resource
Accessed/
Comments
19
Resources for Element 5 Sepsis Diagnosis and Management
CORE RESOURCES
Element 5 - SEPSIS - CORE RESOURCES
Resource
ID
Name of resource
GENERAL SEPSIS REFERENCES
84 Neutropenic Sepsis CG151 2012
Resource owner
Presenter
/Author
NICE
NICE
272 Sepsis - Improving care, improving outcome (via TKN) ASAP Shared Space
(30 mins)
Rooney K
334 Diagnosis and Treatment of Sepsis for ASAP (45 mins) NES
Dilip Nathwani
381 NHS Scotland NEWS & Sepsis Screening Tool
iTunes
NES
435 Antibiotic Use within Intensive Care (34 mins)
NES
Radha
Sundaram
URL link direct to resource
Date Resource
Accessed/ Comments
http://publications.nice.org.uk/neutropenic-sepsisprevention-and-management-of-neutropenic-sepsis-incancer-patients-cg151
http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/U
ploads/2012/Mar/20120307120621_ASAP%20presenta
tion%20Kevin%20Rooney.pdf
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/resources-by-topic/infectiousdiseases/infection/diagnosis-and-treatment-of-sepsisfor-asap.aspx
https://itunes.apple.com/gb/app/nhs-scotland-newssepsis-screening/id657497806?mt=8
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/resources-by-topic/infectiousdiseases/antibiotics/antibiotic-use-within-intensivecare-for-asap.aspx
SEPSIS-INDUCED ORGAN DYSFUNCTION REFERENCES
279 Mechanisms of Sepsis -Induced Organ Dysfunction
(via TKN / Athens login)
Critical Care
Abraham E et al http://www.knowledge.scot.nhs.uk/home/searchMedicine
results.aspx?q=publicid%3a%22ebscocinahl%7c2009738
2007;35(10):2408-16
199%22&pm=fql&expand=true&portal=
20
SUPPLEMENTARY RESOURCES
Element 5 - SEPSIS - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
GENERAL SEPSIS REFERENCES
149 2012 International Guidelines for Management of
Severe Sepsis and Septic Shock
Resource owner
Presenter/Auth
or
URL link direct to resource
Critical Care
Dellinger PR
Medicine ; 2013 ; 41
: 580 -637
213 The sepsis six and the severe sepsis resuscitation
Emerg Med J
Daniels R et al
bundle: a prospective observational cohort study (via 2011;28:6 507-512
TKN / Athens login)
301 ABC of Sepsis 2010 if available
BMJ Books wiley
Blackwell
309 Septic Shock Clinical Vignette (02) (free registration for PAUSE
HCPs) (2 hours)
380 Severe sepsis and septic shock
NEJM
382 Critical Care & Trauma Part 8: Surgical Sepsis
Office of
International
Surgery, U. Toronto
SEPSIS BIOMARKERS REFERENCES
280 Molecular diagnostics of sepsis where are we today? Int J Med Microbiol
(via TKN / Athens login)
2010;300(6):411-3
281 Use of procalcitonin to reduce patients' exposure to Lancet
antibiotics in intensive care units (PRORATA trial):(via 2010;375(9713):463TKN / Athens login)
74
370 Procalcitonin - what does it mean for sepsis
BC Patient Safety &
(YouTube) (46 mins)
Quality Council
371 Novel biomarkers for infection & sepsis 2010 (30 mins) BSAC
Date Resource
Accessed/ Comments
http://www.idsociety.org/Organ_System/
http://emj.bmj.com/search?submit=yes&pubdate_year
=&volume=&firstpage=&doi=&author1=Daniels+R&auth
or2=Nutbeam+T&title=sepsis&andorexacttitle=and&titl
eabstract=&andorexacttitleabs=and&fulltext=&andorex
actfulltext=and&resourcetype=HWCIT&fmonth=&fyear
=2010&tm
Daniels R
BSAC
http://www.pause-online.org.uk
Derek C et al
Jackson A et al
http://www.nejm.org/doi/full/10.1056/NEJMra1208623
http://ptolemy.library.utoronto.ca/content/criticalcare-and-trauma-part-8-surgical-sepsis
Bauer M et al
http://www.sciencedirect.com/science/article/pii/S143
8422110000317
Bouadma L et al http://www.sciencedirect.com/science/article/pii/S014
0673609618791
Reynolds S
http://www.youtube.com/watch?v=ie0QpnRCfbs
Dark P
http://bsac.org.uk/PlayVideoPage.html?url=https://s3eu-west-1.amazonaws.com/havap-2010/08_Paul_Dark
21
Resources for element 6 Acute respiratory tract infection incorporating pneumonia and COPD
CORE RESOURCES
Element 6 - ACUTE RRESPIRATORY TRACT INFECTION - CORE RESOURCES
Resource owner
Presenter
/Author
NES
NES/LearnPro
http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associatedinfections/online-short-courses/antibioticprescribing.aspx
NICE
SAPG
NICE
193 BTS Guideline on Management of Community
Acquired Pneumonia in Adults (2009)
Thorax 2009;64(3)
Lim WS et al
204 Guidelines for the management of hospital-acquired
pneumonia in the UK: Report of the Working Party of
BSAC
409 HPA guidance on use of antiviral agents for the
treatment and prophylaxis of influenza (Oct 2012)
J. Antimicrob.
Chemother., July
2008; 62: 5 - 34
HPA
Masterton RG
http://guidance.nice.org.uk/index.jsp?action=find
http://www.scottishmedicines.org.uk/files/sapg/Comm
unity_Acquired_Pneumonia_Care_Bundle-DRAFTv0.pdf
http://www.brit-thoracic.org.uk/guidelines-and-qualitystandards/community-acquired-pneumonia-in-adultsguideline/
http://jac.oxfordjournals.org/content/62/1/5.full.pdf+h
tml?sid=490c8455-ddc9-4139-8069-a5ded90e4e7b
Resource
ID
Name of resource
GENERAL RESPIRATORY REFERENCES
9 Antibiotic Prescribing for Today's Practitioner (2
hours)
PNEUMONIA & INFLUENZA REFERENCES
90 Pneumonia CG DRAFT
122 Community Acquired Pneumonia Care Bundle
OTHER ACUTE LRTI REFERENCES
201 Chronic obstructive pulmonary disease NICE CG101
262 GOLD Initiative for Chronic Obstructive Lung Disease
2013
265 Atypical Infection? Respiratory Case Study (via TKN)
Date Resource
Accessed/ Comments
http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/
1317131466016
NICE
GOLD
ASAP Shared Space
URL link direct to resource
http://guidance.nice.org.uk/CG101
http://www.goldcopd.org/guidelines-resources.html
Sneddon J
http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/U
ploads/2013/Mar/20130326101614_Atypical%20Case%
20Study%20Resp.pdf
22
Element 6 - ACUTE RRESPIRATORY TRACT INFECTION - CORE RESOURCES
Resource
ID
Name of resource
UPPER RESPIRATORY TRACT INFECTION REFERENCES
88 Respiratory Tract Infections in primary care CG69
Resource owner
Presenter
/Author
NICE
NICE
URL link direct to resource
Date Resource
Accessed/ Comments
http://publications.nice.org.uk/respiratory-tractinfections-antibiotic-prescribing-cg69
SUPPLEMENTARY RESOURCES
Element 6 - ACUTE RESPIRATORY TRACT INFECTION - SUPPLEMENTARY RESOURCES
Name of resource
PNEUMONIA & INFLUENZA REFERENCES
14 Preventing Ventillator Associated Pneumonia (60
mins)
Resource ID
183 Seasonal Influenza in Adults and Children—
Diagnosis, Treatment, Chemoprophylaxis, and
Institutional Outbreak Management: Clinical
Practice Guidelines
195 British Thoracic Society guidelines for the
management of community acquired pneumonia in
children: update 2011
200 Guidelines for the clinical management of patients
with an influenza-like illness during an influenza
pandemic
224 Ventilator associated pneumonia (via TKN / Athens
login)
308 Pneumonia Clinical Vignette (01) (free registration
for HCPs) (2 hours)
482 Analysis Relationships Between Pharmacokinetic
Resource owner
Presenter/Auth
or
URL link direct to resource
NES
LearnPro
Clin Infect Dis 2009 ; Harper SA
48 : 1003 -1032
Thorax 2011;66 (2)
Harris M et al
Thorax 2007;62;1-46 Lim WS
Date Resource
Accessed/ Comments
http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associatedinfections/online-short-courses/preventing-ventilatorassociated-pneumonia.aspx
http://www.idsociety.org/Organism/
http://www.brit-thoracic.org.uk/guidelines-and-qualitystandards/community-acquired-pneumonia-in-childrenguideline/
http://www.brit-thoracic.org.uk/guidelines-and-qualitystandards/influenza/
BMJ 2012;334e3325 Hunter JD
http://www.bmj.com/content/344/bmj.e3325
PAUSE
BSAC
http://www.pause-online.org.uk
Adv Clin Exp Med
Grabowski T et
http://www.advances.am.wroc.pl/pdf/2008/17/3/285.p
23
Element 6 - ACUTE RESPIRATORY TRACT INFECTION - SUPPLEMENTARY RESOURCES
Resource ID
Name of resource
Parameters in silico/in vivo of Selected Antiviral
Drugs Based on Structural Analysis
URTI REFERENCES
38 Management of Sore Throat and Indication for
Tonsillectomy (2010) SIGN 117
160 IDSA Clinical Practice Guideline for Acute Bacterial
Rhinosinusitis in Children and Adults"US Update on
NICE CG 69
161 Clinical Practice Guideline for the Diagnosis and
Management of Group A Streptococcal Pharyngitis:
2012 ( more recent than SIGN 117)
263 Antibiotics for sore throat (via TKN / Athens login)
322 Sore Throat Clinical Vignette (15) (free registration
for HCPs) (90 mins)
Presenter/Auth
Resource owner
or
URL link direct to resource
2008, 17, 3, 285–292 al
df
SIGN
SIGN
Clinical Infectious
Chow AW et al
Diseases ; 2012 ; : e1
-e41
Clinical Infectious
Shulman ST
Diseases ; 2012 ; : 1 17
CDSR 2006(4) Art No Spinks A
CD000023
PAUSE
BSAC
Date Resource
Accessed/ Comments
http://www.sign.ac.uk/guidelines/fulltext/117/index.ht
ml
http://www.idsociety.org/Organ_System/#Lower/Uppe
r Respiratory
http://www.idsociety.org/Organ_System/#Lower/Uppe
r Respiratory
http://onlinelibrary.wiley.com/doi/10.1002/14651858.C
D000023.pub3/abstract;jsessionid=2E5B87CAD4DC6091
A291B972C7D4889F.d01t04
http://www.pause-online.org.uk
24
Resources for element 7 - Urinary tract infection (UTI)
CORE RESOURCES
Element 7 - URINARY TRACT INFECTION (UTI) - CORE RESOURCES
Resource
ID
Name of resource
GENERAL UTI REFERENCES
Local Antimicrobial Guidelines
9 Antibiotic Prescribing for Today's Practitioner
(cases 3 & 7)
Resource owner
Presenter
/Author
NES
NES/LearnPro
http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associated-infections/onlineshort-courses/antibiotic-prescribing.aspx
http://www.sign.ac.uk/guidelines/fulltext/88/index.html
http://publications.nice.org.uk/urinary-tract-infection-inchildren-cg54
http://www.scottishmedicines.org.uk/files/sapg/SAPG_D
ecision_aid_for_UTI_in_older_people_-_May_2013.pdf
http://www.uroweb.org/gls/pdf/18_Urological%20infecti
ons_LR.pdf
43 Management of Suspected Bacterial Urinary Tract
Infections in Adults (updated 2012) SIGN 88
74 Urinary Tract Infection in Children CG54
SIGN
NICE
NICE
108 Decisions Aid for Diagnosis and Management of
Suspected UTI in Older People
253 European Association of Urology Guidelines on
Urological Infections 2013 (Use in conjunction with
local antibiotic prescribing guidelines)
SAPG
SAPG
EAU
Grabe M et al
PYELONEPHRITIS REFERENCES
156 Guidelines for Antimicrobial Treatment of Acute
Uncomplicated Cystitis and Pyelonephritis in Women
(refer to local prescribing guidelines)
299 Reese & Betts' practical approach to infectious
diseases 5th Ed 2003 (on TKN) or alternative
available text book for background information
(UTI/pyelonephritis Chapter used in conjunction
with local guidelines for specific antibiotics)
URL link direct to resource
Clin Infect Dis 2011 ; Gupta K et al
52 : e103 -e120
http://www.idsociety.org/Organ_System/#Genitourinary
Lippincott Williams
and Wilkins
http://www.knowledge.scot.nhs.uk/home/library/books/
books-
Betts RF et al
Date Resource
Accessed/ Comments
CAUTI REFERENCES
25
Element 7 - URINARY TRACT INFECTION (UTI) - CORE RESOURCES
Resource
ID
Name of resource
155 Diagnosis, Prevention, and Treatment of CatheterAssociated Urinary Tract Infection in Adults: 2009
Presenter
Resource owner
/Author
Clin Infect Dis 2010 ; Hooton TM
50 : 625 -663
Date Resource
URL link direct to resource
Accessed/ Comments
http://www.idsociety.org/Organ_System/#Genitourinary
SUPPLEMENTARY RESOURCES
Element 7 - URINARY TRACT INFECTION - SUPPLEMENTARY RESOURCES
Presenter
/Author
URL link direct to resource
Nicolle LE
http://www.idsociety.org/Organ_System/#Genitourinary
Little P et al
http://www.bmj.com/content/340/bmj.b5633?view=long
&pmid=20139213
BSAC
http://www.pause-online.org.uk
PAUSE
BSAC
http://www.pause-online.org.uk
PAUSE
BSAC
http://www.pause-online.org.uk
PAUSE
BSAC
http://www.pause-online.org.uk
Resource
ID
Name of resource
Resource owner
GENERAL UTI REFERENCES
154 Guidelines for the Diagnosis and Treatment of
Clin Infect Dis 2005 ;
Asymptomatic Bacteriuria in Adults
40 : 643 -654
225 Presentation, pattern, and natural course of severe BMJ 2010;340:b5633
symptoms, and role of antibiotics and antibiotic
resistance among patients presenting with suspected
uncomplicated urinary tract infection in primary
care: observational study. (via TKN / Athens login)
313 UTI in Pregnancy Clinical Vignette(06) NB refer to
PAUSE
local policy for choice of antibiotic regimens (free
registration for HCPs) (90 mins)
PYELONEPHRITIS REFERENCES
312 UTI Pyelonephritis Clinical Vignette(05) NB drug
regimens differ from latest guidance (free
registration for HCPs) (2 hours)
315 Pyelonephritis Clinical Vignette (08) NB drug
regimens differ from latest guidance (free
registration for HCPs) (2 hours)
CAUTI REFERENCES
316 Catheter Associated Infection Clinical Vignette(09 )
Date Resource
Accessed/ Comments
26
Element 7 - URINARY TRACT INFECTION - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
(free registration for HCPs) (90 mins)
Resource owner
Presenter
/Author
URL link direct to resource
Date Resource
Accessed/ Comments
27
Resources for Element 8 Skin and soft tissue infection (SSTI)
CORE RESOURCES
Element 8 - SKIN AND SOFT TISSUE INFECTION (SSTI) - CORE RESOURCES
Resource
ID
Name of resource
GENERAL SSTI REFERENCES
165 Practice Guidelines for the Diagnosis and
Management of Skin and Soft Tissue Infections
434 Treating infections in Skin & Soft Tissue in acute and
OPAT settings (60 mins) Video and handouts
Resource owner
Presenter
/Author
URL link direct to resource
Date Resource
Accessed/ Comments
Clin Infect Dis 2005 ; Stevens DL et al http://www.idsociety.org/Organ_System/#Skin & Soft
41 : 1373 -1406
Tissue
NES
Andrew Seaton http://vimeo.com/79984822 for video
and
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/resources-by-topic/infectiousdiseases/antibiotics/treating-infection-in-skin,-softtissue,-bone-and-joints-for-asap.aspx
for handout
CELLULITIS & VENOUS LEG ULCER REFERENCES
216 Diagnosis and management of cellulitis (via TKN /
Athens login)
310 Cellulitis Clinical Vignette (03) (free registration for
HCPs) (90 mins)
369 Venous Leg Ulcers: Infection Diagnosis &
Microbiology Investigation
NECROTISING FASCIITIS AND OTHER SERIOUS SSTI
REFERENCES
227 Necrotising Fasciitis (via TKN / Athens login)
256 Lyme Borreliosis (via TKN / Athens login)
BMJ 2012;
345:e4955
PAUSE
Phoenix G
http://www.bmj.com/content/345/bmj.e4955
BSAC
http://www.pause-online.org.uk
HPA
BMJ 2005;330:830
Lancet 379 Feb
2012(9814);461-76
http://www.hpa.org.uk/Topics/InfectiousDiseases/Infecti
onsAZ/PrimaryCareGuidance/
Hasham S et al
Stanek G et al
http://www.bmj.com/content/330/7495/830
http://www.sciencedirect.com/science/article/pii/S01406
73611601037
28
Element 8 - SKIN AND SOFT TISSUE INFECTION (SSTI) - CORE RESOURCES
Resource
ID
Name of resource
Resource owner
DIABETIC FOOT ULCER REFERENCES
116 Use of antibiotics in people with diabetic foot disease The Diabetic Foot
- a consensus statement
Journal Vol 12 No 2
2009
320 Foot Infection in Diabetic Ulcer Clinical Vignette (13) PAUSE
(free registration for HCPs) (90 mins)
MRSA & PVL-SA REFERENCES
282 Guidance on the diagnosis and management of PVLassociated staphylococcus aureus infections (PLL-SA)
in England (Awaiting Scottish Document in 2014)
203 Guidelines (2008) for the prophylaxis and treatment
of methicillin-resistant Staphylococcus aureus
(MRSA) infections in the United Kingdom
Presenter
/Author
Leese G et al
BSAC
HPA
Public Health
England
J. Antimicrob.
Chemother., May
2009; 63: 849 - 861
Gould FK et al
URL link direct to resource
Date Resource
Accessed/ Comments
http://www.scottishmedicines.org.uk/files/sapg/Use_of_
Antibiotics_in_people_with_diabetic_foot_disease__Consensus_Statement_-_2009.pdf
http://www.pause-online.org.uk
http://www.hpa.org.uk/Publications/InfectiousDiseases/I
nfectionControl/0811Guidanceonthediagnosisandmanag
ementofPVLSA/
http://jac.oxfordjournals.org/content/63/5/849.full.pdf
SUPPLEMENTARY RESOURCES
Element 8 - SKIN AND SOFT TISSUE INFECTION (SSTI) - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
GENERAL SSTI REFERENCES
228 Skin and soft tissue infection diagnosis and
management (Registration required with RPS - fee)
Resource owner
Clinical Pharmacist
2009;1:13-22
Presenter
/Author
Seaton RA
URL link direct to resource
Date Resource
Accessed/ Comments
http://www.pjonline.com/search/all?filter0=skin+and+so
ft+tissue+infection+diagnosis+and+management&filter8=
&filter7%5BClinical+Pharmacist%5D=Clinical+Pharmacist
&filter4=2009&filter5=&filter6=&filter2=**ALL**&filter1
=**ALL**&x=12&y=11
29
Element 8 - SKIN AND SOFT TISSUE INFECTION (SSTI) - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
CELLULITIS & VENOUS LEG ULCER REFERENCES
226 Antibiotics and antiseptics for venous leg ulcers (via
TKN / Athens login)
Resource owner
Presenter
/Author
URL link direct to resource
Date Resource
Accessed/ Comments
Cochrane Database O'Meara S et al http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD
Syst Rev. 2014, Issue
003557.pub5/abstract
1. Art. No.: CD003557.
NECROTISING FASCIITIS AND OTHER SERIOUS SSTI
REFERENCES
167 The Clinical Assessment, Treatment, and Prevention Clin Infect Dis 2006 ; Wormser GP et http://www.idsociety.org/Organism/
of Lyme Disease, Human Granulocytic Anaplasmosis, 43 : 1089 -1134
al
and Babesiosis
DIABETIC FOOT ULCER REFERENCES
92 Diabetic Foot Problems CG119
164 Diagnosis and Treatment of Diabetic Foot Infections
MRSA & PVL-SA REFERENCES
166 Management of Patients with Infections Caused by
Methicillin-Resistant Staphylococcus Aureus
205 Guidelines for UK practice for the diagnosis and
management of (MRSA) infections presenting in the
community
229 Skin and soft tissue infection focus on MRSA
(Registration required with RPS - fee)
NICE
NICE
Clin Infect Dis 2012 ; Lipsky BA
54 : e132 -e173
Clinical Infectious
LIU C et al
Diseases ; 2011 ; 52 :
1 -38
J. Antimicrob.
Nathwani D et al
Chemother.,2008;
61: 976 - 994.
Clinical Pharmacist Seaton RA
2009;1:23-28
http://publications.nice.org.uk/diabetic-foot-problemscg119
http://www.idsociety.org/Organ_System/#Skin & Soft
Tissue
http://www.idsociety.org/Organ_System/#Skin & Soft
Tissue
http://jac.oxfordjournals.org/content/61/5/976.full.pdf
http://www.pjonline.com/search/all?filter0=skin+and+so
ft+tissue+infection+diagnosis+and+management&filter8=
&filter7%5BClinical+Pharmacist%5D=Clinical+Pharmacist
&filter4=2009&filter5=&filter6=&filter2=**ALL**&filter1
=**ALL**&x=12&y=11
OTHER SSTI REFERENCES
30
Element 8 - SKIN AND SOFT TISSUE INFECTION (SSTI) - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
364 Acne Vulgaris (30 mins)
366 Atopic eczema in children: Management of atopic
eczema in children from birth up to the age of 12
years
367 Fungal Skin and Nail Infections Primary Care Quick
Reference Guide
431 NICE CKS Guidelines on Fungal nail & skin infections
Resource owner
NICE CKS
NICE
Presenter
/Author
HPA
NICE
NICE
URL link direct to resource
http://cks.nice.org.uk/acne-vulgaris
http://publications.nice.org.uk/atopic-eczema-inchildren-cg57
Date Resource
Accessed/ Comments
http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1
240294785726
http://cks.nice.org.uk/
31
Resources for Element 9 Surgical infection & prophylaxis
CORE RESOURCES
Element 9 - SURGICAL INFECTION AND PROPHYLAXIS -CORE RESOURCES
Resource
ID
Presenter
/Author
Name of resource
GENERAL SURGICAL INFECTION & PROPHYLAXIS
REFERENCES (also covering MRSA)
41 Antibiotic Prophylaxis in Surgery (2008) SIGN 104
87 Surgical Site Infection CG74
119 SAPG Good Practice Recommendations for Surgical
and Procedural Antibiotic Prophylaxis 2012
Resource owner
139 Clinical practice guidelines for antimicrobial
prophylaxis in surgery
Am J Health Syst
Pharm 2013; 70:
195-283
Bratzler DW et
al
British Journal of
Haematology 2011,
155, 308–317
NICE
Davies JM et al
ASPLENIA & VALVULAR HEART DISEASE REFERENCES
232 Review of guidelines for the prevention and treatment
of infection in patients with an absent or dysfunctional
spleen
89 NICE Prophylaxis Against Infective Endocarditis CG64
TRAUMA REFERENCES
470 The Management of Severe Open Lower Limb
Fractures (BOAST 4) 2009
SIGN
NICE
SAPG
BRITISH
ORTHOPAEDIC
ASSOCIATION &
BAPRAS
NICE
SAPG
NICE
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.sign.ac.uk/guidelines/fulltext/104/index.html
http://publications.nice.org.uk/surgical-site-infection-cg74
http://www.scottishmedicines.org.uk/files/sapg/Good_pra
ctice_recommendations_for_surgical_prophylaxis_2012.pd
f
http://www.idsociety.org/Antimicrobial_Agents/#Antimicr
obial Prophylaxis for Surgery
http://www.sbp.com.br/pdfs/Review_guidelinesfortheprev
entionandtreatmentofinfectioninpatientswithaabsentordys
functionalsp.pdf
http://publications.nice.org.uk/prophylaxis-againstinfective-endocarditis-cg64
http://www.boa.ac.uk/LIB/LIBPUB/Documents/BOAST%20
4%20%20The%20Management%20of%20Severe%20Open%20Lo
wer%20Limb%20Fractures.pdf
32
SUPPLEMENTARY RESOURCES
Element 9 - SURGICAL INFECTION AND PROPHYLAXIS - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
GENERAL SURGICAL INFECTION & PROPHYLAXIS
REFERENCES
9 Antibiotic Prescribing for Today's Practitioner (2
hours)
Resource owner
Presenter
/Author
NES
NES/LearnPro
58 Surgical Prophylaxis for gram positive and gram
negative infections (30 mins)
339 SAPG Guidance on Re-Dosing Antimicrobials for
Surgical Prophylaxis
BSAC
233 Infections associated with orthopedic implants (via
TKN / Athens login)
382 Critical Care & Trauma Part 8: Surgical Sepsis
476 Surgical Site Infection Surveillance
Curr Op Infect Dis
2006;19:349-356
Office of
International
Surgery, U. Toronto
HPS
493 NICE Quality Standard QS49 Surgical site infection
NICE
SAPG
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associated-infections/onlineshort-courses/antibiotic-prescribing.aspx
Mark Willox
http://www.online-webpresentations.com/SSI/day1/pdf/Mark%20Wilcox.pdf
J Sneddon A
http://www.scottishmedicines.org.uk/files/sapg/SAPG_Rec
MacDonald
ommendations_for_Redosing_Antibiotics_for_Surgical_Prophylaxis.pdf
Trampuz A et al http://www.knowledge.scot.nhs.uk/
Jackson A et al
NICE
http://ptolemy.library.utoronto.ca/content/critical-careand-trauma-part-8-surgical-sepsis
http://www.hps.scot.nhs.uk/haiic/sshaip/surgicalsiteinfecti
onsurveillance.aspx
http://publications.nice.org.uk/surgical-site-infection-qs49
33
Resources for Element 10 Pharmacokinetics (PK) pharmacodynamics (PD) and therapeutic drug monitoring (TDM)
CORE RESOURCES
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - CORE RESOURCES
Resource
ID
Name of resource
GENERAL PK, PD AND TDM REFERENCES
103 Therapeutic Drug Monitoring of Antimicrobials via
TKN / Athens login)
143 Vancomycin Therapeutic Monitoring: Review and
Recommendations from the ASHP, IDSA and SIDP
Task Force
468 Antimicrobial Pharmacokinetics Webinar Part 1 (26
mins)
509 Antimicrobial Pharmacokinetics Webinar Part 2 (40
mins)
511 Antimicrobial Pharmacokinetics Webinar Part 3 (42
mins)
189 Development of teicoplanin dosage guidelines for
patients treated within an (OPAT) programme
273 Development of gentamicin guidelines for synergistic
use (via TKN)
335 Antibiotic pharmacokinetic and pharmacodynamic
indices : for ASAP (1 hour and 40 mins)
Resource owner
Br J Pharmacol
Am J Health-Syst
Pharm ; 2009 ; 66 :
82 -98
NES
NES
NES
JAC (2009) 64 (1):
181-187.
ASAP Shared Space
Presenter/Auth
or
URL link direct to resource
Roberts JA et al http://onlinelibrary.wiley.com.proxy.knowledgeservices.or
g/doi/10.1111/j.1365-2125.2011.04080.x/pdf
Rybak M et al
http://www.idsociety.org/Antimicrobial_Agents/
Alison Thomson https://attendee.gotowebinar.com/recording/4788799007
120449538
Alison Thomson https://attendee.gotowebinar.com/recording/1870728132
351983618
Alison Thomson https://attendee.gotowebinar.com/recording/7518889677
424862209
Lamont E et al http://jac.oxfordjournals.org/content/64/1/181.full
Thomson A
NES
Andrew
Lovering
383 Pharmacodynamics of antibiotics : focus on outcome NES
& resistance : for ASAP (60 mins)
Andrew
Lovering
59 The impact of recent antimicrobial interventions - the BSAC
PK/PD debate & what the evidence says (30 mins)
Date Resource
Accessed/
Comments
William Hope
http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Uplo
ads/2011/Mar/20110323151742_Gent-dosing_synergy.pdf
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/resources-by-topic/infectiousdiseases/antibiotics/antibiotic-pharmacokinetic-andpharmacodynamic-indices-for-asap.aspx
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/resources-by-topic/infectiousdiseases/antibiotics/pharmacodynamics-of-antibioticsfocus-on-outcome-resistance-for-asap.aspx
http://www.online-webpresentations.com/BSAC_HAVAP2010/
34
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - CORE RESOURCES
Resource
ID
Name of resource
AMINOGLYCOSIDE & GLYCOPEPTIDE REFERENCES
338 Gentamicin and Vancomycin Training Resource (4
hours)
Resource owner
NES/LearnPro
395 SAPG Intravenous gentamicin (GG&C and Hartford) & SAPG
Vancomycin (Continuous & pulsed)
512 Gentamicin and Vancomycin Dosing in Amputees (Via ASAP/TKN
TKN registration and Athens Password required)
Presenter/Auth
or
URL link direct to resource
Date Resource
Accessed/
Comments
Alison Thomson http://www.nes.scot.nhs.uk/education-and-training/bytheme-initiative/healthcare-associated-infections/onlineshort-courses/gav-gentamicin-and-vancomycin.aspx
SAPG
http://www.scottishmedicines.org.uk/SAPG/Quality_Impro
vement/Gentamicin_and_Vancomycin
Steve
http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Page
McCormick
s/Forums/DiscussionTopics.aspx?ContainerID=209407&top
icID=3643
SUPPLEMENTARY RESOURCES
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - SUPPLEMENTARY
RESOURCES
Resource
ID
Presenter
/Author
Name of resource
GENERAL PK, PD AND TDM REFERENCES
396 Examples of dosage regimen design (registration
required with RPS - fee)
Resource owner
397 Why do therapeutic drug monitoring (registration
required with RPS - fee)
The Pharmaceutical Thomson AH
Journal2004;273:153
The Pharmaceutical Thomson AH
Journal2004;273:188
398 Variability in drug dosage requirements (registration The Pharmaceutical Thomson AH
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.pjonline.com/search/all?filter0=&filter8=Tho
mson&filter7%5BThe+Pharmaceutical+Journal%5D=The+P
harmaceutical+Journal&filter4=2004&filter5=273&filter6=1
88&filter2=**ALL**&filter1=**ALL**&x=11&y=11#libraryresults
http://www.pjonline.com/search/all?filter0=&filter8=Tho
mson&filter7%5BThe+Pharmaceutical+Journal%5D=The+P
harmaceutical+Journal&filter4=2004&filter5=273&filter6=1
53&filter2=**ALL**&filter1=**ALL**&x=7&y=12#libraryresults
http://www.pjonline.com/search/all?filter0=&filter8=Tho
35
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - SUPPLEMENTARY
RESOURCES
Resource
ID
Name of resource
required with RPS - fee)
399 Back to basics: pharmacokinetics (registration
required with RPS - fee)
Resource owner
Journal2004;272:806
Presenter
/Author
The Pharmaceutical Thomson AH
Journal2004;272:769
400 Bespoke pharmacy: Tailoring medicines to the needs Hospital
Thomson AH
of patients - the role of therapeutic drug monitoring Pharmacist2003;10:1
(registration required with RPS - fee)
60
235 Continuous v intermittent infusions of antibiotics for Cochrane Database Shiu J et al
the treatment of severe acute infections (via TKN / Syst Rev 2013(3) Art
Athens login)
No CD008481
PK IN SPECIAL PATIENT GROUPS REFERENCES
512 Gentamicin and Vancomycin Dosing in Amputees
ASAP/TKN
(Via TKN registration and Athens Password required)
441 UKCPA Drug Dosing in Extremes of Body Weight in
Critically Ill Patients 2013
502 How should antibiotics be dosed in obesity? UKMI
Q&A 378.1
100 Dosing of Antibiotics in Obesity (via TKN / Athens
login)
Steve
McCormick
UKCPA
NICE Evidence
UKMI
Current Opinion in
Infectious Diseases
Janson B,
Thursky K
518 Altered vancomycin pharmacokinetics in obese and J Antimicrob
morbidly obese patients: what we have learned over Chemother.
Grace E
URL link direct to resource
mson&filter7%5BThe+Pharmaceutical+Journal%5D=The+P
harmaceutical+Journal&filter4=2004&filter5=272&filter6=8
06&filter2=**ALL**&filter1=**ALL**&x=7&y=11#libraryresults
http://www.pjonline.com/search/all?filter0=&filter8=&filte
r7%5BThe+Pharmaceutical+Journal%5D=The+Pharmaceuti
cal+Journal&filter4=2004&filter5=272&filter6=769&filter2=
**ALL**&filter1=**ALL**&x=15&y=10
http://www.pjonline.com/search/all?filter0=&filter8=omso
n&filter7%5BHospital+Pharmacist%5D=Hospital+Pharmacis
t&filter4=2003&filter5=10&filter6=160&filter2=**ALL**&fi
lter1=**ALL**&x=10&y=10
http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD0
08481.pub2/abstract
Date Resource
Accessed/
Comments
http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Page
s/Forums/DiscussionTopics.aspx?ContainerID=209407&top
icID=3643
http://www.nes.scot.nhs.uk/media/2536057/vt3_drug_do
sing_ukcpa_doc__for_resources__website__jan_2014.pdf
https://www.evidence.nhs.uk/topic/obesity?om=%5B%7B
%22srn%22%3A%5B%22%20ukmi%20%22%5D%7D%5D
http://www.knowledge.scot.nhs.uk/home/searchresults.aspx?q=publicid%3a%22OVIDmedl%7c23041773%2
2&pm=fql&expand=true&portal=
http://jac.oxfordjournals.org/content/67/6/1305.long
36
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - SUPPLEMENTARY
RESOURCES
Resource
ID
Name of resource
J Antimicrob Chemother. 2012;67(6):1305-10.the
past 30 years
456 Clinical Pharmacokinetics of Penicillins,
Cephalosporins and Aminoglycosides in the Neonate
Resource owner
2012;67(6):1305-10.
Pharmaceuticals
2010; 3 (8): 25682591.
457 Clinical pharmacokinetics of vancomycin in the
Clinics (Sao Paulo).
neonate: a review
2012 July; 67(7):
831–837
237 Antibiotic dosing in critical illness
J Antimicrob
Chemother 2011;66
S2ii23-ii31
525 Pharmacokinetic issues for antibiotics in the
Crit Care Med 2009;
critically ill patient
37(3): 840 - 851
514 Influence of multiple courses of therapy on
J. Antimicrob.
aminoglycoside clearance in adult patients with
Chemother. (2013)
cystic fibrosis
68 (6): 1338-1347
515 Population pharmacokinetics of tobramycin in
Clinical
patients with and without cystic fibrosis (via
Pharmacokinetics
TKN/Athens login)
2013 52 (4): 289-301
516 Pharmacokinetic and pharmacodynamic
J pharmacokinet
optimisation of intravenous tobramycin dosing
pharmacodynam
among children with cystic fibrosis. (via TKN/Athens 2014;41(1): 71-79
login)
517 Once versus three-times daily regimens of
Lancet.
tobramycin treatment for pulmonary exacerbations 2005;365(9459):573of cystic fibrosis--the TOPIC study: a randomised
8
controlled trial (via TKN/Athens login)
519 Dose optimisation of antibiotics in children:
Int J Antimicrobial
application of pharmacokinetics/pharmacodynamics Agents; 43(3): 223-
Presenter
/Author
URL link direct to resource
Pacifici, G.M
http://www.mdpi.com/1424-8247/3/8/2568
Pacifici GM
Allegaert K
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400177/
Date Resource
Accessed/
Comments
MacKenzie C et http://jac.oxfordjournals.org/content/66/suppl_2/ii25.long
al
Roberts JA et al http://clinicalevidence.pbworks.com/w/file/fetch/5556237
4/REVISION%20GENERALIDADES%20ANTIBIOTICOS.pdf
Alghanem S et al http://jac.oxfordjournals.org/content/68/6/1338.full.pdf+h
tml?hwoaspck=true
Hennig S et al
www.knowledge.scot.nhs.uk/
Sherwin CMT et www.knowledge.scot.nhs.uk/
al
Smyth A et al
www.knowledge.scot.nhs.uk/
Downes KJ et al www.knowledge.scot.nhs.uk/
37
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - SUPPLEMENTARY
RESOURCES
Resource
ID
Name of resource
in paediatrics (via TKN/Athens login)
520 Pharmacokinetics in children
Resource owner
230
Merck Manual
Online
Presenter
/Author
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.merckmanuals.com/professional/pediatrics/pr
inciples_of_drug_treatment_in_children/pharmacokinetics
_in_children.html
521 Pharmacokinetics in the Elderly
Merck Manual
Merck
http://www.merckmanuals.com/professional/geriatrics/dr
Online
ug_therapy_in_the_elderly/pharmacokinetics_in_the_elde
rly.html
522 Unique Aspects of Antimicrobial Use in Older Adults Clin Infect Dis. (2005) Faulkener CM et http://cid.oxfordjournals.org/content/40/7/997.long
40 (7): 997-1004.
al
523 Optimal Dosing Design for Antibiotic Therapy in the Recent Pat Anti-Infec Noreddin A et al http://www.eurekaselect.com/82160/article
Elderly: A Pharmacokinetic and Pharmacodynamic
Drug Disc 2008;3:45Perspective
52
524 Pharmacokinetics and Safety of Antimicrobial Agents Rev Inf Dis 1985;
Chow AW,
http://www.amchp.org/programsandtopics/womensDuring Pregnancy (old article for background info
7(3): 287-313
Jeweson PJ
health/CDC/ANTIBIOTICS/Chow.pdf
only - refer to local guidelines re drug dosing etc)
526 Pharmacokinetics in pregnancy
Best Prac & Res Clin Dawes M
http://analysis3.com/download.php?id=14636
Obs & Gyn 2001;
Chowienczyk PJ
15(6): 819-26
PK, PD & TDM WITH OTHER DRUG GROUPS
503 Therapeutic drug monitoring (TDM) of antifungal
agents: guidelines from the British Society for
Medical Mycology
Merck
J Antimicrob
Ashbee HR et al
Chemother (2013)
doi:
10.1093/jac/dkt508
480 Optimizing antifungal choice and administration (via Curr Med Research Andes D
TKN / Athens login)
Opin. 29, Sup 4,
2013, 13–18
481 Sequential treatment of cytomegalovirus infection or Transpl Infect Dis
Caldes A et al
disease with a short course of intravenous
2010: 12: 204-212
http://jac.oxfordjournals.org/content/early/2013/12/28/ja
c.dkt508.full?hwoaspck=true&sid=94fb36c1-9153-44c8b5a5-bddaddddb708
http://informahealthcare.com.proxy.knowledgeservices.or
g/doi/pdf/10.1185/03007995.2012.761135
www.knowledge.scot.nhs.uk/
38
Element 10 - ANTIMICROBIAL PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD) & THERAPEUTIC DRUG MONITORING (TDM) - SUPPLEMENTARY
RESOURCES
Resource
ID
Name of resource
ganciclovir followed by oral valganciclovir: efficacy.
safety, and pharmacokinetics (via TKN / Athens
login)
482 Analysis Relationships Between Pharmacokinetic
Parameters in silico/in vivo of Selected Antiviral
Drugs Based on Structural Analysis
483 The Role of Therapeutic Drug Monitoring in the
Management of Patients With Human
Immunodeficiency Virus Infection (via TKN / Athens
login)
Resource owner
Presenter
/Author
Adv Clin Exp Med
Grabowski T et
2008, 17, 3, 285–292 al
Therapeutic Drug
Monitoring. 33
(3):265-74 2011
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.advances.am.wroc.pl/pdf/2008/17/3/285.pdf
Pretorius E et al www.knowledge.scot.nhs.uk/
39
Resources for Element 11 Data analysis and presentation Incorporating interpretation of audit data
CORE RESOURCES
Element 11 - DATA ANALYSIS AND PRESENTATION INCORPORATING INTERPRETATION OF AUDIT DATA - CORE RESOURCES
Resource
owner
NES
Presenter/Author URL link direct to resource
Vicky Elliott
https://attendee.gotowebinar.com/recording/7181743125700807938
NES
Vicky Elliott
https://attendee.gotowebinar.com/recording/6376940196590164993
473 Data for quality improvement for ASAP
(14 mins)
474 Utilising and presenting data from
routine sources for ASAP (18 mins)
475 Introduction to Control Charts and
Statistical Process Control (SPC) for
ASAP (16 mins)
507 Presenting Data
NES
Andrea Patton
https://attendee.gotowebinar.com/recording/4826215385075476226
NES
Vicky Elliott
https://attendee.gotowebinar.com/recording/6282428376111341058
NES
Gwen Bayne
https://attendee.gotowebinar.com/recording/4981498315782606082
NES
Gwen Bayne
https://attendee.gotowebinar.com/recording/3571299886369227010
508 The Power of Local Data for ASAP (20
mins)
494 Surgical Prophylaxis Indicator Report
NES
Frances Kerr?
Still to be recorded
495 National Services Scotland Annual
Report
NHS National
Services
Scotland
Resource
ID
Name of resource
446 Introduction to routine data for ASAP
(16 mins)
472 Basic statistics for ASAP (17 mins)
SAPG
Date
Resource
Accessed/
Comments
http://www.scottishmedicines.org.uk/files/sapg/Surgical_
Prophylaxis_Indicator_Report_October_2013.pdf
http://www.nhsnss.org/pages/publications/annual_reports.php
SUPPLEMENTARY RESOURCES
Element 11 - DATA ANALYSIS AND PRESENTATION INCORPORATING INTERPRETATION OF AUDIT DATA - SUPPLEMENTARY RESOURCE
Name of resource
7 Patterns of Antimicrobial Use and Resistance in
Scotland(MSc) (56 mins)
Resource ID
Resource owner
NES
Presenter
/Author
William
Malcolm
URL link direct to resource
http://www.video3uk.com/login.aspx
Date Resource
Accessed/
Comments
40
Element 11 - DATA ANALYSIS AND PRESENTATION INCORPORATING INTERPRETATION OF AUDIT DATA - SUPPLEMENTARY RESOURCE
Name of resource
53 Antimicrobial resistance surveillance, improving
relevance and outputs 20 mins)
109 From intermittent antibiotic point prevalence
surveys to quality improvement: experience in
Scottish hospitals
447 Excel 2007 training course
Resource ID
Resource owner
BSAC
Antimicrob Res Inf
Cont 2013;2:3
Microsoft office
Presenter
/Author
Prof Alasdair
McGowan
Malcolm W et al
URL link direct to resource
http://bsac.org.uk/events/past-events-2011/springmeeting-agm-2011/spring-meeting-2011/
http://www.aricjournal.com/content/2/1/3
Date Resource
Accessed/
Comments
http://office.microsoft.com/en-us/training/excel-2007training-coursesHA010218987.aspx?CTT=5&origin=HA010225533
41
Resources for Element 12 Meningitis and CNS Infection
CORE RESOURCES
Element 12 - MENINGITIS AND CNS INFECTION - CORE RESOURCES
Resource
ID
Name of resource
MENINGITIS REFERENCES
35 Management of Invasive Meningococcal Disease in
Children & Young People (2008) SIGN 102
77 Bacterial meningitis and meningococcal septicaemia:
Management of bacterial meningitis and
meningococcal septicaemia in children and young
people younger than 16 years in primary and
secondary care CG102 2010
147 Practice Guidelines for the Management of Bacterial
Meningitis
(This covers adults whereas UK documents just up to
16 years)
393 Guidance for public health management of
meningococcal disease in the UK
450 Early management of suspected bacterial meningitis
and meningococcal septicaemia in adults
451 Early management of suspected bacterial meningitis
and meningococcal septicaemia in adults algorithm
496 Viral Meningitis (via TKN)
Resource owner
Presenter
/Author
SIGN
NICE
URL link direct to resource
http://www.sign.ac.uk/guidelines/fulltext/102/index.html
NICE
http://publications.nice.org.uk/bacterial-meningitis-andmeningococcal-septicaemia-cg102
Clin Infect Dis ; 2004 Tunkel AR et al
; 39 : 1267 -1284
http://www.idsociety.org/Organ_System/#Central Nervous
System (CNS)
HPA
http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/119
4947389261
http://www.britishinfection.org/drupal/sites/default/files/
meningitisJI2003.pdf
http://www.britishinfection.org/drupal/sites/default/files/
MeningitisAlgorithm03.pdf
http://web.ebscohost.com/dynamed/detail?sid=bdc5104f6727-41be-bbc3c4bad5b4ed6a%40sessionmgr113&vid=1&hid=123&bdata
=JnNpdGU9ZHluYW1lZC1saXZlJnNjb3BlPXNpdGU%3d#db=
dme&AN=114531
Journal of Infection
2003; 46: 75-77
BIS
Dynamed
ENCEPHALITIS REFERENCES
452 Management of suspected viral encephalitis in adults Journal of Infection
– Association of British Neurologists and British
2012; 64(4);347-73
Infection Association National Guidelines
Date Resource
Accessed/
Comments
Heyderman RS
et al
BIS
Solomon T et al http://www.journalofinfection.com/article/S01634453(11)00563-9/fulltext
42
Element 12 - MENINGITIS AND CNS INFECTION - CORE RESOURCES
Resource
ID
Name of resource
Resource owner
Presenter
/Author
URL link direct to resource
Date Resource
Accessed/
Comments
URL link direct to resource
Date Resource
Accessed/
Comments
OTHER CNS INFECTION REFERENCES - SEE
SUPPLEMENTARY RESOURSES SECTION
SUPPLEMENTARY RESOURCES
Element 12 - MENINGITIS AND CNS INFECTION - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
Resource owner
GENERAL CNS INFECTION REFERENCES
284 SWAB Guidelines on Antibacterial Therapy of Patients SWAB
with Bacterial Central Nervous System Infections
MENINGITIS REFERENCES
82 Bacterial Meningitis and meningococcal sepatcaemia
in children and young people (QS19)
NICE
Presenter
/Author
Dutch Working http://www.swab.nl/swab/cms3.nsf/uploads/FE54A05708
Party on
2AA54CC1257A2B00293B1D/$FILE/SWAB_CNSguideline_%
Antimicrobial
20June12.pdf
Policy
NICE
http://publications.nice.org.uk/quality-standard-forbacterial-meningitis-and-meningococcal-septicaemia-inchildren-and-young-qs19
448 Antibiotics for preventing meningococcal infections
CDSR 2013, Issue 10. Trestioreanu A Z http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD0
Art. No.: CD004785
(via TKN / Athens login)
et al
04785.pub5/abstract
394 Lessons from research for doctors in training:
Meningitis research
http://www.meningitis.org/health-professionals/doctorsrecognition and early management of meningococcal foundation
in-training
disease in children and young people 3rd Ed
449 Cerebrospinal fluid lactate concentration to
Cochrane DARE 2011 Huy Ntet al
http://onlinelibrary.wiley.com/o/cochrane/cldare/articles/
distinguish bacterial from aseptic meningitis: a
Issue 3
DARE-12011001453/frame.html
systematic review and meta‐analysis (Structured
abstract) (via TKN / Athens login)
43
Element 12 - MENINGITIS AND CNS INFECTION - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
ENCEPHALITIS REFERENCES
148 The Management of Encephalitis: Clinical Practice
Guidelines
OTHER CNS INFECTION REFERENCES
167 The Clinical Assessment, Treatment, and Prevention of
Lyme Disease, Human Granulocytic Anaplasmosis, and
Babesiosis
454 British Infection Society guidelines for the diagnosis
and treatment of tuberculosis of the central nervous
system in adults and children
234 The rational use of antibiotics in the treatment of
brain abscess (via TKN / Athens login)
168 Practice Parameter: Treatment of Nervous System
Lyme Disease (AAN)" (Endorsed by IDSA)
Resource owner
Presenter
/Author
Clin Infect Dis 2008 ; Tunkel AR et al
47 : 303 -327
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.idsociety.org/Organ_System/#Central Nervous
System (CNS)
Clin Infect Dis 2006 ; Wormser GP et http://www.idsociety.org/Organism/
43 : 1089 -1134
al
Journal of Infection
(2009) 59, 167-187
Thwaites G et al http://www.britishinfection.org/drupal/sites/default/files/
CNS%20TB%202009%20Thwaites.pdf
Br J Neurosurg
Louvois J et al http://www.cwmicrobiology.nhs.uk/NeuroPDFs/brain_abs
2000;14(6):525-30
cess.pdf
Neurology ; 2007 ; 69 Halperin JJ et al http://www.idsociety.org/Organism/
: 91 -102
44
Resources for Element 13 Endocarditis and Cardiovascular Infection
CORE RESOURCES
Element 13 - ENDOCARDITIS AND CARDIOVASCULAR INFECTION - CORE RESOURCES
Resource
ID
Name of resource
GENERAL ENDOCARDITIS REFERENCES
Local antimicrobial guidelines on the treatment of
infective endocarditis
89 Prophylaxis Against Infective Endocarditis CG64 2008
Resource owner
Presenter
/Author
NICE
NICE
202 Guidelines for the diagnosis and antibiotic treatment J.
Gould FK et al
of endocarditis in adults: a report of the Working Party Antimcrob.Chemoth
of BSAC
er., Feb 2012;
67:269-289
289
Guidelines on the prevention, diagnosis, and
European Heart
ESC Guideline
treatment of infective endocarditis (new version 2009) Journal
2009;30(19):2369(one year more recent than NICE CG 64 so possibly
2413
CORE)
URL link direct to resource
Date Resource
Accessed/
Comments
http://publications.nice.org.uk/prophylaxis-againstinfective-endocarditis-cg64
http://jac.oxfordjournals.org/content/early/2012/02/13/ja
c.dks039.full
http://eurheartj.oxfordjournals.org/content/30/19/2369.fu
ll
CARDIOVASCULAR IMPLANTABLE ELECTRONIC DEVICE
INFECTION REFERENCES
145 Cardiovascular Implantable Electronic Device
Infections
Circulation ; 2010 ;
121 : 458 -477
Baddour LM
http://www.idsociety.org/Organ_System/
45
SUPPLEMENTARY RESOURCES
Element 13 - ENDOCARDITIS AND CARDIOVASCULAR INFECTION - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
GENERAL ENDOCARDITIS REFERENCES
311 Infective Endocarditis Clinical Vignette(04) NB refer to
local guidelines for specific drug therapy - good for
background information only) (2 hours)
206 Guidelines for the prevention of endocarditis: report
of the Working Party of the British Society for
Antimicrobial Chemotherapy 2006 (cited in NICE
CG64)
288 Infective endocarditis (via TKN / Athens login)
Resource owner
Presenter
/Author
URL link direct to resource
PAUSE
BSAC
http://www.pause-online.org.uk
J Antimicrob
Chemother 2006;
57:1034-42
Gould FK et al
http://jac.oxfordjournals.org/content/57/6/1035.full.pdf
N Engl J Med 2013;
368(15):1425-33
Hoen B et al
http://www.knowledge.scot.nhs.uk/home/searchresults.aspx?q=publicid:%22OVIDmedl|23574121%22&pm
=fql&expand=true&portal=
Date Resource
Accessed/
Comments
46
Resources for Element 14 Bone & Joint Infections
CORE RESOURCES
Element 14 - BONE AND JOINT INFECTION - CORE RESOURCES
Resource
ID
Name of resource
GENERAL BONE & JOINT INFECTION REFERENCES
92 Diabetic Foot Problems CG119
Resource owner
Presenter
/Author
NICE
NICE
URL link direct to resource
Date Resource
Accessed/
Comments
http://publications.nice.org.uk/diabetic-foot-problemscg119
116 Use of antibiotics in people with diabetic foot disease - The Diabetic Foot
Leese G et al
http://www.scottishmedicines.org.uk/files/sapg/Use_of_A
a consensus statement
Journal Vol 12 No 2
ntibiotics_in_people_with_diabetic_foot_disease_2009
_Consensus_Statement_-_2009.pdf
163 Diagnosis and Management of Prosthetic Joint
Clinical Infectious
Osmon DR et al http://www.idsociety.org/Organ_System/#Skeletal (Bones
Infection: Clinical Practice Guidelines by the Infectious Diseases ; 2013 ; 56 :
& Joints)
Diseases Society of America
1 -25
260 Bacterial septic arthritis in adults (via TKN / Athens
Lancet 2010;375:
Matthews CJ
http://www.sciencedirect.com/science/article/pii/S014067
login)
846-55
3609615956
433 Treating infections in Bone & Joint in acute and OPAT NES
Andrew Seaton
settings
INTERACTION AND ADR REFERENCES
442 Stockley's Drug Interactions
Medicines Complete
http://www.medicinescomplete.com/mc/stockley/current/
443 Electronic Medicines Compendium eMC
Datapharm
http://www.medicines.org.uk/emc/
SUPPLEMENTARY RESOURCES
Element 14 - BONE AND JOINT INFECTION - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
GENERAL BONE & JOINT INFECTION REFERENCES
233 Infections associated with orthopedic implants (via
TKN / Athens login)
Resource owner
Curr Op Infect Dis
2006;19:349-356
Presenter
/Author
URL link direct to resource
Date Resource
Accessed/
Comments
Trampuz A et al http://www.knowledge.scot.nhs.uk/
47
Element 14 - BONE AND JOINT INFECTION - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
259 Prosthetic Joint Associated Infections (via TKN /
Athens login)
Resource owner
Best Prac Res Clin
Rheumatol
2006;20(6):1045
321 Septic Arthritis Clinical Vignette (14) (free registration PAUSE
for HCPs) (2 hours)
Presenter
/Author
Zimmerli W
BSAC
URL link direct to resource
http://www.bprclinrheum.com/article/S15216942(06)00107-0/abstract
Date Resource
Accessed/
Comments
http://www.pause-online.org.uk
48
Resources for Element 15 Gastrointestinal (GI) infections
CORE RESOURCES
Element 15 - GASTROINTESTINAL (GI) INFECTION - CORE RESOURCES
Resource
ID
Name of resource
GENERAL GI INFECTION REFERENCES
157 Guidelines for the Selection of Anti-infective Agents
for Complicated Intra-abdominal Infections
Local Antimicrobial Prescribing Guidelines on the
eradication of H pylori and other GI infections
290 EASL clinical practice guidelines on the management
of ascites, spontaneous bacterial peritonitis, and
hepatorenal syndrome in cirrhosis (via TKN / Athens
login)
PERITONITIS REFERENCES
291 Spontaneous Bacterial peritonitis: recent guidelines
and beyond (via TKN / Athens login)
HELICOBACTER PYLORI REFERENCES
497 Test and treat for Helicobacter pylori (HP) in
Dyspepsia
Quick Reference Guide for Primary Care
Resource owner
Clin Infect Dis 2010 ; Solomkin JS
501 : 133 -164
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.idsociety.org/Organ_System/#IntraAbdominal
Journal of
European
http://www.sciencedirect.com/science/article/pii/S016882
Hepatology
Association for 7810004782
2010;53(3):397-417 the Study of the
Liver
GUT 2012;61:297310
Weist R et al
http://gut.bmj.com/content/61/2/297.full
British Infection
Association
BIA
http://www.britishinfection.org/drupal/sites/default/files/f
iles/Helicobacter%20guidance%20final%20for%20web%20
27_06_12.pdf
BIA
http://www.britishinfection.org/drupal/sites/default/files/f
iles/Norovirus%20report.pdf
NICE
http://publications.nice.org.uk/diarrhoea-and-vomiting-inchildren-cg84
https://www.gov.uk/government/organisations/publichealth-england/series/immunisation-against-infectiousdisease-the-green-book
INFECTIOUS DIARRHOEA REFERENCES
477 Guidelines for the management of norovirus
BIA
outbreaks in acute and community health and social
care settings 2012
490 Diarrhoea and vomiting in children NICE CG 84 2009 NICE
379 Immunisation against infectious disease: the Green
Book (Rotavirus)
Presenter
/Author
Department of
Health
49
Element 15 - GASTROINTESTINAL (GI) INFECTION - CORE RESOURCES
Resource
ID
Name of resource
340 Travax (travelers' diarrhoea) (free registration
required)
Resource owner
Health Protection
Scotland
PANCREATITIS REFERENCES
318 Pancreatitis Clinical Vignette (11) (free registration
for HCPs) (60 mins)
PAUSE
Presenter
/Author
BSAC
URL link direct to resource
http://www.travax.nhs.uk/
Date Resource
Accessed/
Comments
http://www.pause-online.org.uk
SUPPLEMENTARY RESOURCES
Element 15 - GASTROINTESTINAL (GI) INFECTION SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
HELICOBACTER PYLORI REFERENCES
405 Evidence-based guidelines from ESPGHAN and
NASPGHAN for Helicobacter pylori infection in
children
94 Dyspepsia (inc H Pylori) SIGN 68 2003
INFECTIOUS DIARRHOEA REFERENCES
151 Practice Guidelines for the Management of
Infectious Diarrhea
254 Cryptosporidiosis and its treatment
255 Diagnosis and treatment of amebiasis
BILIARY INFECTIONS REFERENCES
458 Diagnosis and Management of Primary Sclerosing
Resource owner
J Ped Gastro Nutr
2011 ;53(2):230-43
SIGN
Presenter
/Author
Koletzko S et al http://www.naspghan.org/userassets/Documents/pdf/PositionPapers/H%20pylori%20%20PAP%20version.pdf
http://www.sign.ac.uk/guidelines/fulltext/68/index.html
Clin Infect Dis 2001 ; Guerrant RL et
32 : 331 -350
al
CDC
Clin Infect Dis
1999;29:1117-25
URL link direct to resource
Date Resource
Accessed/
Comments
Petri WA
http://www.idsociety.org/Organ_System/#Gastrointestinal
(GI)
http://www.cdc.gov/parasites/crypto/health_professionals
/tx.html
http://cid.oxfordjournals.org/content/29/5/1117.full
HEPATOLOGY 2010; Chapman R et al http://www.aasld.org/practiceguidelines/Documents/Pract
50
Element 15 - GASTROINTESTINAL (GI) INFECTION SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
Cholangitis
Resource owner
51(2): 660-78
Presenter
/Author
URL link direct to resource
ice%20Guidelines/PSC_2-2010.pdf
Date Resource
Accessed/
Comments
51
Resources for Element 16 - Antibiotics used in pregnancy, neonates and paediatrics
CORE RESOURCES
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - CORE RESOURCES
Resource
ID
Name of resource
Resource owner
PREGNANCY & LACTATION REFERENCES
238 Toxbase Monographs for drugs in pregnancy and
Toxbase
breastfeeding (free registration for healthcare
professionals - one registration per pharmacy)
240 Sepsis in Pregnancy, Bacterial (Green-top 64a) 2012 RCOG
241 Sepsis following Pregnancy, Bacterial (Green-top
64b) 2012
RCOG
43 Management of Suspected Bacterial Urinary Tract
Infections in Adults (updated 2012) SIGN 88
478 Lactmed
SIGN
US National Library
of Medicine
479 Medications and Mothers' Milk 2012 if available
Hale Publishing
491 NICE CG37 Postnatal care (also covers neonates)
NICE
492 Antibiotics for mastitis in breastfeeding women (via Jahanfar S, Ng CJ,
TKN / Athens login)
Teng CL
Presenter
/Author
Hale T
NICE
Cochrane
Database of
Systematic
Reviews 2013,
Issue 2. Art. No.:
CD005458
376 Drugs in Pregnancy and Lactation: A Reference Guide Lippincott Williams & Briggs G
to Fetal and Neonatal Risk 9th ed (via TKN)
Wilkins
524 Pharmacokinetics and Safety of Antimicrobial Agents Rev Inf Dis 1985;
Chow AW,
During Pregnancy (old article for background info
7(3): 287-313
Jeweson PJ
only - refer to local guidelines re drug dosing etc)
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.toxbase.org/
http://www.rcog.org.uk/womens-health/clinicalguidance/sepsis-pregnancy-bacterial-green-top-64a
http://www.rcog.org.uk/womens-health/clinicalguidance/sepsis-following-pregnancy-bacterial-green-top64b
http://www.sign.ac.uk/guidelines/fulltext/88/index.html
http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT
http://publications.nice.org.uk/postnatal-care-cg37
http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD0
05458.pub3/abstract;jsessionid=1A612ACABA2A10EC5B2B
EFE9CDFEF885.f01t03
http://www.knowledge.scot.nhs.uk/
http://www.amchp.org/programsandtopics/womenshealth/CDC/ANTIBIOTICS/Chow.pdf
52
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - CORE RESOURCES
Resource
ID
Name of resource
NEONATE REFERENCES
83 Antibiotics in Early Onset Neonatal Infection CG149
440 Neonatal Formulary (6th ED) with updates 2011 (if
available)
PAEDIATRIC REFERENCES
195 British Thoracic Society guidelines for the
management of community acquired pneumonia in
children: update 2011
462 Cystic Fibrosis Foundation evidence-based guidelines
for management of infants with cystic fibrosis (US
guidance) (via TKN / Athens login)
375 British National Formulary for Children (BNF-C)
77 Bacterial meningitis and meningococcal septicaemia:
Management of bacterial meningitis and
meningococcal septicaemia in children and young
people younger than 16 years in primary and
secondary care CG102 (2010)
407 Bronchiolitis in children (2006) SIGN 91
498 NICE CG 132 Guidance on Caesarian section
91 Bronchiolitis in Children CG DRAFT
35 Management of Invasive Meningococcal Disease in
Children & Young People (2008) SIGN 102
71 Feverish Illness in Children CG160
74 Urinary Tract Infection in Children CG54
Resource owner
Presenter
/Author
NICE
NICE
Wiley
Hey E (Editor)
Thorax 2011;66 (2)
Harris M et al
J Pediatr. 2009
Dec;155(6
Suppl):S73-93.
BMJ/RPS
NICE
URL link direct to resource
Date Resource
Accessed/
Comments
http://publications.nice.org.uk/antibiotics-for-early-onsetneonatal-infection-cg149
http://www.neonatalformulary.com/default.asp
http://www.brit-thoracic.org.uk/guidelines-and-qualitystandards/community-acquired-pneumonia-in-childrenguideline/
Borowitz D et al http://www.guideline.gov/content.aspx?f=rss&id=43789
NICE
http://www.medicinescomplete.com/about/index.htm
http://publications.nice.org.uk/bacterial-meningitis-andmeningococcal-septicaemia-cg102
SIGN
NICE
NICE
SIGN
SIGN
NICE
NICE
SIGN
http://www.sign.ac.uk/guidelines/fulltext/91/index.html
http://publications.nice.org.uk/caesarean-section-cg132
http://guidance.nice.org.uk/
http://www.sign.ac.uk/guidelines/fulltext/102/index.html
NICE
NICE
NICE
NICE
http://publications.nice.org.uk/feverish-illness-in-childrencg160
http://publications.nice.org.uk/urinary-tract-infection-inchildren-cg54
53
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - CORE RESOURCES
Resource
ID
Name of resource
Resource owner
38 Management of Sore Throat and Indication for
SIGN
Tonsillectomy (2010) SIGN 117
506 Introduction to paediatric pharmaceutical care (use NES
generic sections and chapter on childhood infection)
Presenter
/Author
SIGN
NES
URL link direct to resource
http://www.sign.ac.uk/guidelines/fulltext/117/index.html
Date Resource
Accessed/
Comments
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educationalresources/resources-by-topic/child-health/introduction-topaediatric-pharmaceutical-care.aspx
SUPPLEMENTARY RESOURCES
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
PREGNANCY & LACTATION REFERENCES
402 Preterm Prelabour Rupture of Membranes (Green
Top 44)
404 Recommended strategies for Intrapartum
Antimicrobial Prophylaxis (IAP) for Perinatal Group B
Streptococcal Disease.
211 Timing of prophylactic antibiotics for preventing
postpartum infectious morbidity in women
undergoing cesarean delivery (Protocol) (via TKN /
Athens login)
239 Antibacterial medication use during pregnancy and
risk of birth defects
455 Antibiotic Use in Pregnancy and Lactation
Resource owner
Presenter
/Author
RCOG
URL link direct to resource
perinatology.com
http://www.rcog.org.uk/files/rcogcorp/GTG44PPROM28022011.pdf
http://www.perinatology.com/protocols/GBS.htm
CDSR 2011, Issue 12. Baxter JK et al
Art. No.: CD009516
http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD0
09516/full
Arch Pediat Adolesc Crider KS et al
Med
2009;163(11):978-85
OBSTETRICS &
Nahum GG et al
GYNECOLOGY 2006;
107(5): 1120-38
http://archpedi.jamanetwork.com/article.aspx?articleid=3
82406
Date Resource
Accessed/
Comments
http://www.amchp.org/programsandtopics/womenshealth/CDC/ANTIBIOTICS/Nahum.pdf
54
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
246 Group B Streptococcal Disease, Early Onset (Greentop 36) 2012
Resource owner
RCOG
247 Genital Herpes in Pregnancy, Management (Greentop 30) 2007
RCOG
248 Chickenpox in Pregnancy (Green-top 13) 2007
RCOG
526 Pharmacokinetics in pregnancy
Best Prac & Res Clin
Obs & Gyn 2001;
15(6): 819-26
524 Pharmacokinetics and Safety of Antimicrobial Agents Rev Inf Dis 1985;
During Pregnancy (old article for background info
7(3): 287-313
only - refer to local guidelines re drug dosing etc)
NEONATE REFERENCES
285 Management of antibiotic-resistant infection in the
newborn (via TKN / Athens login)
287 Improving antibiotic prescribing in neonatal units:
time to act (via TKN / Athens login)
457 Clinical pharmacokinetics of vancomycin in the
neonate: a review
Arch Dis Child Educ
Pract Ed
2011;96:122-127
Arch Dis Child Fetal
Neonat Ed
2012;97:F141-F146
Clinics (Sao Paulo).
2012 July; 67(7):
831–837
PEDIATRICS
2011.128 (3): 1-6
403 Recommendations for the Prevention of Perinatal
Group B Streptococcal (GBS) Disease Policy
Statement American Academy of Paediatrics 2011
456 Clinical Pharmacokinetics of Penicillins,
Pharmaceuticals
Cephalosporins and Aminoglycosides in the Neonate 2010; 3 (8): 2568-
Presenter
/Author
Dawes M
Chowienczyk PJ
URL link direct to resource
http://www.rcog.org.uk/womens-health/clinicalguidance/prevention-early-onset-neonatal-group-bstreptococcal-disease-greenhttp://www.rcog.org.uk/womens-health/clinicalguidance/management-genital-herpes-pregnancy-greentop-30
http://www.rcog.org.uk/womens-health/clinicalguidance/chickenpox-pregnancy-green-top-13
http://analysis3.com/download.php?id=14636
Chow AW,
Jeweson PJ
http://www.amchp.org/programsandtopics/womenshealth/CDC/ANTIBIOTICS/Chow.pdf
Gray JW et al
http://ep.bmj.com/content/96/4/122.full
Date Resource
Accessed/
Comments
Bedford Russell http://fn.bmj.com/content/97/2/F141.full
A
Pacifici GM
Allegaert K
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400177/
http://pediatrics.aappublications.org/content/early/2011/
07/28/peds.2011-1466.full.pdf
Pacifici, G.M
http://www.mdpi.com/1424-8247/3/8/2568
55
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
PAEDIATRIC REFERENCES
408 Guidelines on Paediatric Urology (European
Association of Urology 2012)
411 Recommendations for treatment of childhood nonsevere pneumonia (via TKN / Athens login)
412 Antibiotics for acute otitis media in children (Review)
Jan2013 (via TKN / Athens login)
453 Management of suspected viral encephalitis in
children – Association of British Neurologists and
British Paediatric Allergy, Immunology and Infection
Group National Guidelines
95 Cystic fibrosis (pseudomonas lung infection) colistimethate sodium and tobramycin TA276 (2013)
Resource owner
2591.
URL link direct to resource
Journal of Infection
2012; 64(5); 449-77
http://www.uroweb.org/gls/pdf/21_Paediatric_Urology_L
R_August%202012.pdf
Grant GB et al http://blog.utp.edu.co/maternoinfantil/files/2010/08/Guia
_Lancet_Neumonia_severa.pdf
Venekamp RP et http://summaries.cochrane.org/CD000219/antibiotics-foral
middle-ear-infection-acute-otitis-media-in-children
Kneen R et al
http://www.journalofinfection.com/article/S01634453(11)00562-7/fulltext
NICE
NICE
490 Diarrhoea and vomiting in children NICE CG 84 2009 NICE
NICE
366 Atopic eczema in children: Management of atopic
NICE
eczema in children from birth up to the age of 12
years
406 Guidelines on the Management of Acute and Chronic Scottish Paediatric
Peritoneal Dialysis
Renal and Urology
Network
NICE
198 BTS guidelines for the management of pleural
infection in children
516 Pharmacokinetic and pharmacodynamic
EAU
Presenter
/Author
Lancet Infect Dis
2009;9: 185-96
Cochrane
Date Resource
Accessed/
Comments
Tekgul S et al
Renal Unit,
Yorkhill
http://publications.nice.org.uk/colistimethate-sodium-andtobramycin-dry-powders-for-inhalation-for-treatingpseudomonas-lung-ta276
http://publications.nice.org.uk/diarrhoea-and-vomiting-inchildren-cg84
http://publications.nice.org.uk/atopic-eczema-in-childrencg57
http://www.clinicalguidelines.scot.nhs.uk/Renal%20Unit%
20Guidelines/YOR-REN030%20Management%20of%20Acute%20and%20Chronic%
20Peritoneal%20Dialysis%20Oct%2010%20Revision%201.p
df
http://www.brit-thoracic.org.uk/guidelines-and-qualitystandards/pleural-infection-in-children/
Thorax
Balfour-Lynne
2005;60(Suppl I):i1– IM
i21
J pharmacokinet
Sherwin CMT et www.knowledge.scot.nhs.uk/
56
Element 16 - ANTIBIOTICS USED IN PREGNANCY, NEONATES AND PAEDIATRICS - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
optimisation of intravenous tobramycin dosing
among children with cystic fibrosis.
519 Dose optimisation of antibiotics in children:
application of pharmacokinetics/pharmacodynamics
in paediatrics (via TKN/Athens login)
520 Pharmacokinetics in children
Resource owner
pharmacodynam
2014;41(1): 71-79
Int J Antimicrobial
Agents; 43(3): 223230
Merck Manual
Online
Presenter
/Author
al
URL link direct to resource
Date Resource
Accessed/
Comments
Downes KJ et al www.knowledge.scot.nhs.uk/
Merck
http://www.merckmanuals.com/professional/pediatrics/pr
inciples_of_drug_treatment_in_children/pharmacokinetics
_in_children.html
57
Resources for Element 17 Sexually transmitted infection (STI), human immunodeficiency virus (HIV) & other blood
borne virus (BBV)
CORE RESOURCES
Element 17 - STI, HIV AND OTHER BBV - CORE RESOURCES
Resource
ID
Name of resource
GENERAL STI/BBV/HIV REFERENCES
64 HIV-STI Pathology (free registration for HCPs) (90
minutes)
STI REFERENCES
40 Management of Genital Chlamidia tracomatis
Infection (2009) SIGN 109
417 Sexually Transmitted Infections in Primary Care
(although primary care is good summary document)
65 HIV-STI Bacterial STIs and related conditions (free
registration required for HCPs) (2 hours and 30 mins)
66 HIV-STI Genital Ulcer Disease (including syphilis)
(free registration required for HCPs) (60 mins)
413 UK National Guideline for the Management of Pelvic
Inflammatory Disease 2011
BBV REFERENCES
68 HIV-STI Viral Hepatitis (free registration required for
HCPs) (3 hours)
85 Hepatitis B (chronic) diagnosis and management in
children & adults (CG 165)
362 Hepatitis Drug Interactions Website (Liverpool
University)
363 SIGN 133: Management of Hepatitis C (July 2013)
424 UK consensus guidelines for the use of the protease
Resource owner
Presenter
/Author
URL link direct to resource
e-Learning for Health NHS
http://www.e-lfh.org.uk/home/
SIGN
http://www.sign.ac.uk/guidelines/fulltext/109/index.html
BASSH
e-Learning for Health NHS
http://www.bashh.org/documents/Sexually%20Transmitte
d%20Infections%20in%20Primary%20Care%202013.pdf
http://www.e-lfh.org.uk/home/
e-Learning for Health NHS
http://www.e-lfh.org.uk/home/
BASSH
http://www.bashh.org/documents/3572.pdf
e-Learning for Health NHS
http://www.e-lfh.org.uk/home/
NICE
http://publications.nice.org.uk/hepatitis-b-chronic-cg165
Liverpool University
SIGN
Aliment Pharmacol
NICE
Date Resource
Accessed/
Comments
http://www.hep-druginteractions.org/
http://www.sign.ac.uk/guidelines/fulltext/133/index.html
Ramachandran http://onlinelibrary.wiley.com.proxy.knowledgeservices.or
58
Element 17 - STI, HIV AND OTHER BBV - CORE RESOURCES
Resource
ID
Name of resource
inhibitors boceprevir and telaprevir in genotype 1
chronic hepatitis C infected patients (via TKN /
Athens login)
425 EASL Issue 8 (April 2012) Revised Clinical Practice
Guidelines on the Management of Chronic Hepatitis
B with corrigendum
HIV REFERENCES
69 HIV-STI 12 Specific Assessment and Management of
HIV (free registration required for HCPs) (60 mins)
361 HIV Drug Interactions Website (Liverpool University)
401 BHIVA and BIA Guidelines for the Treatment of
Opportunistic Infection in HIV-seropostive
individuals 2011
418 BHIVA guidelines summaries for patients
419 Introduction to combination therapy (good summary
document for those new to subject)
485 Impact of antiretroviral dosing frequency and pill
burden on adherence among newly diagnosed,
antiretroviral-naïve HIV patients (via TKN / Athens
login)
486 Adherence to Therapy, Treatment Success, and the
Prevention of Resistance (via TKN / Athens login)
Resource owner
Ther 2012; 35(6):
647-62
Presenter
/Author
P et al
URL link direct to resource
g/doi/10.1111/j.1365-2036.2012.04992.x/full
Journal of
EASL
Hepatology 2012 (57
):167–185
http://www.easl.eu/_clinical-practice-guideline/issue-8april-2012-revised-clinical-practice-guidelines-on-themanagement-of-chronic-hepatitis-b
e-Learning for Health NHS
http://www.e-lfh.org.uk/home/
Liverpool University
BHIVA
http://www.hiv-druginteractions.org/
http://www.bhiva.org/documents/Guidelines/OI/hiv_v12_i
s2_Iss2Press_Text.pdf
BHIVA
iBase
http://www.bhiva.org/guidelines-summaries.aspx
http://i-base.info/guides/starting
Int J STD & AIDS
2012; 23: 351–355
Buscher A et al
Infect Diseases in
Jain SK et al
Clin Pract; 14(4):S1518 2006
487 Novel modular teaching of HIV patients and effect on Tropical Med & Int Busari O
adherence to HAART (via TKN / Athens login)
Health 17(s1: 18
2012
Date Resource
Accessed/
Comments
http://www.knowledge.scot.nhs.uk/
http://www.knowledge.scot.nhs.uk/
http://www.knowledge.scot.nhs.uk/
59
SUPPLEMENTARY RESOURCES
Element 17 - STI, HIV AND OTHER BBV - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
GENERAL STI/BBV/HIV REFERENCES
93 NES Sexual and Reproductive Health
128 Sexual Health in General Practice (Free Registration
for HCPs) (2 hours)
410 UK National Guideline on the Management of
Sexually Transmitted Infections and Related
Conditions in Children and Young People 2010
420 Clinical Care Options Website (free registration for
HCPs)
Resource owner
Presenter
/Author
NES
RCGP
URL link direct to resource
Date Resource
Accessed/
Comments
www.portal.scot.nhs.uk
http://elearning.rcgp.org.uk/course/view.php?search=infe
ction&morelesson=1&id=33
http://www.bashh.org/documents/2674.pdf
BASSH
Clinical Care Options
(CCO)
http://www.clinicaloptions.com/
STI REFERENCES
46 Neisseria gonorrhea – the first untreatable infection BSAC
Prof Catherine
Ison
67 HIV-STI HPV Infection (free registration required for e-Learning for Health NHS
HCPs) 3 hours)
247 Genital Herpes in Pregnancy, Management (Green- RCOG
top 30) 2007
249 BASHH Clinical Effectiveness Group Guidelines (have BASSH
referred to specific guidelines elsewhere)
BBV REFERENCES
76 Hepatitis B - Tenofovir disoproxil TA173
NICE
NICE
80 Hepatitis C (genotype 1) - Telaprevir TA252
NICE
NICE
http://bsac.org.uk/events/past-events-2013/bsac-springmeeting-2013/bsac-spring-meeting-agm-2013-videos/
http://www.e-lfh.org.uk/home/
http://www.rcog.org.uk/womens-health/clinicalguidance/management-genital-herpes-pregnancy-greentop-30
http://www.bashh.org/BASHH/Guidelines/Guidelines/BAS
HH/Guidelines/Guidelines.aspx
http://publications.nice.org.uk/tenofovir-disoproxil-forthe-treatment-of-chronic-hepatitis-b-ta173
http://publications.nice.org.uk/telaprevir-for-thetreatment-of-genotype-1-chronic-hepatitis-c-ta252
60
Element 17 - STI, HIV AND OTHER BBV - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
81 Hepatitis C (genotype 1) - Boceprevir TA253
Resource owner
NICE
Presenter
/Author
NICE
URL link direct to resource
http://publications.nice.org.uk/boceprevir-for-thetreatment-of-genotype-1-chronic-hepatitis-c-ta253
86 Hepatitis C (Children and Young People)
NICE
NICE
http://publications.nice.org.uk/peginterferon-alfa-andPeginterferon Alfa & Ribavirin TA300
ribavirin-for-treating-chronic-hepatitis-c-in-children-andyoung-people-ta300
152 Diagnosis, Management and Treatment of Hepatitis HEPATOLOGY ; 2011 Ghany MG et al http://www.idsociety.org/Organism/
C (AASLD)
; 54 : 1433 -1444
423 European Association for the Study of Liver
EASL
www.easl.eu
484 Interferon: an important step forward in treating
The Pharmaceutical Bryan J
http://www.pjonline.com/
hepatitis C infection (Registration required with RPS - Journal2008;280:753
fee)
481 Sequential treatment of cytomegalovirus infection or Transpl Infect Dis
Caldes A et al
http://www.knowledge.scot.nhs.uk/
disease with a short course of intravenous
2010: 12: 204-212
ganciclovir followed by oral valganciclovir: efficacy.
safety, and pharmacokinetics (via TKN - Athens login)
HIV REFERENCES
252 BHIVA Guidelines (have referred to specific
BHIVA
http://www.bhiva.org/ClinicalGuidelines.aspx
guidelines elsewhere)
250 HIV infection pathology and disease progression
Clinical Pharmacist Weston R et al http://www.pjonline.com/search/all?filter0=hiv+infection+
(registration with RPS required - fee)
2009;1: 387
pathology+and+disease+progression&filter8=weston&filter
7%5BClinical+Pharmacist%5D=Clinical+Pharmacist&filter4=
&filter5=&filter6=&filter3%5Bcpd_article%5D=cpd_article&
filter2=**ALL**&filter1=**ALL**&
254 Cryptosporidiosis and its treatment
CDC
http://www.cdc.gov/parasites/crypto/health_professionals
/tx.html
415 Treating opportunistic infections in HIV-infected
CHIVA
http://www.chiva.org.uk/professionals/health/guidelines/c
children
omplications/treating-oi.html
416 Guidelines for the management of HIV infection in BHIVA
http://www.bhiva.org/PregnantWomen2012.aspx
pregnant women 2012
Date Resource
Accessed/
Comments
61
Element 17 - STI, HIV AND OTHER BBV - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
181 Guidelines for the Prevention and Treatment of
Opportunistic Infections Among HIV-Exposed and
HIV-Infected Children
421 HIV pharmacists association (free registration
required for pharmacists)
422 Guidelines for the Management of Hepatitis Viruses
in Adults Infected with HIV 2013
483 The Role of Therapeutic Drug Monitoring in the
Management of Patients With Human
Immunodeficiency Virus Infection (via TKN / Athens
login)
426 Toronto General Hospital Immunodeficiency Clinic
Drug Information/Interactions
488 Pharmacists: Partners in Health Care for HIV-Infected
Patients
Resource owner
The Pediatric
Infectious Disease
Journal
November 6, 2013
HIV PA
Presenter
/Author
URL link direct to resource
Siberry GK et al http://www.idsociety.org/Organism/
hivpa.org
BHIVA
Therapeutic Drug
Monitoring. 33
(3):265-74 2011
http://www.bhiva.org/hepatitis-2013.aspx
Pretorius E et al http://www.knowledge.scot.nhs.uk/
Toronto General
Hospital
NY State DoH AIDS
Institute 2000-2013
302 ABC of HIV and AIDS 6th Ed 2012 if available (comes BMJ Books Wiley
highly recommended but would need to be
Blackwell
purchased)
Date Resource
Accessed/
Comments
http://hivclinic.ca/main/drugs_home.html
http://www.hivguidelines.org/clinical-guidelines/hiv-andpharmacy/pharmacists-partners-in-health-care-for-hivinfected-patients/
Alder MW
62
Resources for Element 18 Tropical infectious diseases
CORE RESOURCES
Element 18 - TROPICAL INFECTIOUS DISEASES - CORE RESOURCES
Resource
ID
Name of resource
Resource owner
GENERAL TROPICAL DISEASES REFERENCES
340 Travax (Free registration required for HCPs or possibly Health Protection
access via The Knowledge Network)
Scotland
MALARIA REFERENCES
469 Guidelines for malaria prevention in travelers from the
United Kingdom 2013
243 Malaria in pregnancy prevention (Green-top 54A)
2010
244 Malaria in pregnancy diagnosis & treatment (Greentop 54B) 2010
349 The British Infection Society UK Malaria Treatment
Guidelines (2007)
351 The British Infection Society Malaria Algorithm for
Diagnosis & Initial Management
OTHER TROPICAL DISEASES REFERENCES
255 Diagnosis and treatment of amebiasis
Public Health
England
RCOG
RCOG
Journal of Infection
(2007); 54: 111-121
BIS
Presenter
/Author
http://www.travax.nhs.uk/
Chiodini PL et al http://www.hpa.org.uk/webw/HPAweb&HPAwebStandard
/HPAweb_C/1195733823080?p=1191942128258
http://www.rcog.org.uk/prevention-malaria-pregnancygreen-top-54a
http://www.rcog.org.uk/diagnosis-and-treatment-malariapregnancy-green-top-54b
Laloo DG et al http://www.britishinfection.org/drupal/sites/default/files/
malariatreatmentBIS07.pdf
http://www.britishinfection.org/drupal/sites/default/files/
MalariaAlgorithm07.pdf
Clin Infect Dis
Petri WA
1999;29:1117-25
BMJ2011;342:d2651 Gray DJ et al
257 Review: Diagnosis and Management of
Schistosomiasis (via TKN / Athens login)
427 Rabies: Guidance on Prophylaxis and Management in Health Protection
Humans in Scotland
Scotland
428 Leishmaniasis
Clin Med 2011;
11(5): 492-7
355 WHO Ebola, Marburg and Crimean Congo
WHO
Haemorrhagic Fever Factsheets
URL link direct to resource
Date Resource
Accessed/
Comments
Moore EM,
Lockwood DN
http://cid.oxfordjournals.org/content/29/5/1117.full
http://www.bmj.com/content/342/bmj.d2651
http://www.documents.hps.scot.nhs.uk/abouthps/hpn/rabies-guidelines-2013.pdf
http://www.clinmed.rcpjournal.org/content/11/5/492.full.
pdf
http://www.who.int/mediacentre/factsheets/en/
63
Element 18 - TROPICAL INFECTIOUS DISEASES - CORE RESOURCES
Resource
ID
Name of resource
222 The evolving threat of antimicrobial resistance
Resource owner
WHO
Presenter
/Author
URL link direct to resource
http://whqlibdoc.who.int/publications/2012/97892415031
81_eng.pdf
Date Resource
Accessed/
Comments
SUPPLEMENTARY RESOURCES
Element 18 - TROPICAL INFECTIOUS DISEASES - SUPPLEMENTARY RESOURCES
Resource
ID
Presenter
/Author
Name of resource
GENERAL TROPICAL DISEASE REFERENCES
342 National Travel Health Network and Centre
343 CDC Health Information for International Travel
(Yellow Book)
345 Travel Health (60 mins)
Resource owner
379 Immunisation against infectious disease: the green
book
DoH
429 Hunter's Tropical Medicine and Emerging Infectious
Disease: Expert Consult -2013 Online and Print, 9e if
available
430 Manson's Tropical Diseases 23rd Edition 2013 if
available
Elsevier
Magill AJ et al
(ED)
Elsevier
Farrar J et al
(Ed)
The Hospital for
Tropical Diseases
Journal of Infection
(2007); 54: 107-110
http://www.thehtd.org/Malaria%20guideline_final_June20
13.pdf
Swales CA et al http://www.britishinfection.org/drupal/sites/default/files/
malariapreventionBIS07.pdf
MALARIA REFERENCES
348 The London Hospital of Tropical Medicine Malaria
Guidelines 2013
350 The British Infection Society New Guidelines on
Malaria Prevention: A Summary
NaTHNaC
CDC
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.nathnac.org/pro/index.htm
http://wwwnc.cdc.gov/travel/page/yellowbook-home2012
http://www.nes.scot.nhs.uk/media/1912665/travel_health
_interactive.pdf
https://www.gov.uk/government/organisations/publichealth-england/series/immunisation-against-infectiousdisease-the-green-book
NES
64
Element 18 - TROPICAL INFECTIOUS DISEASES - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
OTHER TROPICAL DISEASES REFERENCES
354 WHO Expert Consultation on Rabies 2013
Resource owner
WHO
Presenter
/Author
URL link direct to resource
Date Resource
Accessed/
Comments
http://apps.who.int/iris/bitstream/10665/85346/1/978924
0690943_eng.pdf
65
Resources for Element 19 Chronic respiratory tract infections - tuberculosis (TB), cystic fibrosis (CF) and non-CF
bronchiectasis
CORE RESOURCES
Element 19 - CHRONIC RESPIRATORY INFECTION - TB, CF & BRONCHIECTASIS - CORE RESOURCES
Resource
ID
Name of resource
TUBERCULOSIS REFERENCES
70 Tuberculosis NICE CG 117
197 Guidelines for the prevention and management of
Mycobacterium tuberculosis infection and disease in
adult patients with chronic kidney disease
258 Extensively drug-resistant tuberculosis (via TKN /
Athens login)
298 WHO Guidelines for the programmatic management
of drug-resistant tuberculosis 2011
CYSTIC FIBROSIS REFERENCES
464 Antibiotic Treatment for Cystic Fybrosis – 3rd Edition
Report of the UK Cystic Fibrosis Trust Antibiotic
Working Group
95 Cystic fibrosis (pseudomonas lung infection) colistimethate sodium and tobramycin TA276 (2013)
501 Oxford Textbook of Medicine 2003 see chapter on
cystic fibrosis (via TKN)
NON-CF BRONCHIECTASIS REFERENCES
192 The BTS Guideline for non-CF Bronchiectasis
Resource owner
Presenter
/Author
URL link direct to resource
NICE
NICE
http://publications.nice.org.uk/tuberculosis-cg117
Thorax
2010;65:559e570
Milburn H et al
http://www.brit-thoracic.org.uk/guidelines-and-qualitystandards/tuberculosis-guideline/
Lancet Infect Dis
2009;9: 19-30
WHO
Jassal M
http://www.ncbi.nlm.nih.gov/pubmed/18990610
Date Resource
Accessed/
Comments
http://whqlibdoc.who.int/publications/2011/97892415015
83_eng.pdf
Cystic Fibrosis Trust
http://cysticfibrosis.org.uk/media/82010/antibiotictreatment-for-cystic-fibrosis-may-09.pdf
NICE
NICE
Oxford University
Press
Warrell D
http://publications.nice.org.uk/colistimethate-sodium-andtobramycin-dry-powders-for-inhalation-for-treatingpseudomonas-lung-ta276
www.knowledge.scot.nhs.uk/
Thorax (Volume 65, Pasteur MC et al http://www.brit-thoracic.org.uk/guidelines-and-qualitySupplement 1) 2010
standards/bronchiectasis-guideline/
66
SUPPLEMENTARY RESOURCES
Element 19 - CHRONIC RESPIRATORY INFECTION - TB, CF & BRONCHIECTASIS - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
TUBERCULOSIS REFERENCES
169 Diagnosis, Treatment and Prevention of
Nontuberculous Mycobacterial Diseases
Resource owner
Presenter
/Author
Am J Resp Crit care Griffith DE et al
Med 2007 ; 175 : 367
-416
199 Management of opportunist mycobacterial infections: Thorax 2000;55:210– Campbell IA et
Joint Tuberculosis Committee guidelines 1999
218
al
297 WHO Treatment of tuberculosis: guidelines for
WHO
national programmes 4th Ed 2009
317 Tuberculosis Clinical Vignette (10)( free registration
PAUSE
BSAC
required for HCPs) Good if limited access to patients
with TB (3 hours)
323 Tuberculosis Clinical Vignette (16)(free registration
PAUSE
BSAC
required for HCPs) ) Good if limited access to patients
with TB (2 hours)
454 British Infection Society guidelines for the diagnosis
Journal of Infection Thwaites G et al
and treatment of tuberculosis of the central nervous (2009) 59, 167-187
system in adults and children
CYSTIC FIBROSIS REFERENCES
445 Cystic Fibrosis & OPAT - What can we learn?
BSAC
463 Antibiotic Prescribing Guidelines in Adults with Cystic NHS Lothian
Fibrosis - 2013 V2 Example of local adaptation of
Cystic Fibrosis Trust Guidance
461 Standards of care for patients with cystic fibrosis: a
Journal of cystic
European consensus
fibrosis 2005; 4: 7 –
26
462 Cystic Fibrosis Foundation evidence-based guidelines J Pediatr. 2009
URL link direct to resource
Date Resource
Accessed/
Comments
http://www.idsociety.org/Organism/
http://www.brit-thoracic.org.uk/guidelines-and-qualitystandards/non-tuberculous-mycobacteria/
http://www.who.int/tb/publications/tb_treatmentguidelin
es/en/index.html
http://www.pause-online.org.uk
http://www.pause-online.org.uk
http://www.britishinfection.org/drupal/sites/default/files/
CNS%20TB%202009%20Thwaites.pdf
Iara-Mina
http://e-opat.com/downloads
Sequeios
McCabe D et al Awaiting link to NES website
Barreto C et al
http://www.sciencedirect.com/science/article/pii/S156919
9304002139
Borowitz D et al http://www.guideline.gov/content.aspx?f=rss&id=43789
67
Element 19 - CHRONIC RESPIRATORY INFECTION - TB, CF & BRONCHIECTASIS - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
for management of infants with cystic fibrosis.
500 Cystic Fibrosis Pharmacological Management
(registration required with RPS - fee)
499 Cystic Fibrosis Physiology and Diagnosis (registration
required with RPS - fee)
514 Influence of multiple courses of therapy on
aminoglycoside clearance in adult patients with cystic
fibrosis
515 Population pharmacokinetics of tobramycin in
patients with and without cystic fibrosis (via
TKN/Athens login)
516 Pharmacokinetic and pharmacodynamic optimisation
of intravenous tobramycin dosing among children with
cystic fibrosis (via TKN/Athens login).
517 Once versus three-times daily regimens of tobramycin
treatment for pulmonary exacerbations of cystic
fibrosis--the TOPIC study: a randomised controlled
trial (via TKN/Athens login)
Resource owner
Dec;155(6
Suppl):S73-93.
Clinical Pharmacist
2011;3:245
Clinical Pharmacist
2011;3: 239
J. Antimicrob.
Chemother. (2013)
68 (6): 1338-1347
Clinical
Pharmacokinetics
2013 52 (4): 289-301
J pharmacokinet
pharmacodynam
2014;41(1): 71-79
Lancet.
2005;365(9459):5738
Presenter
/Author
URL link direct to resource
Smyth S
http://www.pjonline.com/
Cuevas OA
http://www.pjonline.com/
Date Resource
Accessed/
Comments
Alghanem S et al http://jac.oxfordjournals.org/content/68/6/1338.full.pdf+h
tml?hwoaspck=true
Hennig S et al
www.knowledge.scot.nhs.uk/
Sherwin CMT et www.knowledge.scot.nhs.uk/
al
Smyth A et al
www.knowledge.scot.nhs.uk/
68
Resources for Element 20 Fungal infections
CORE RESOURCES
Element 20 - FUNGAL INFECTION - CORE RESOURCES
Resource
ID
Name of resource
GENERAL FUNGAL AND ANTIFUNGAL REFERENCES
Available textbook(s) for background information
367 Fungal Skin and Nail Infections Primary Care Quick
Reference Guide
431 NICE CKS Guidelines on Fungal nail & skin infections
432 Guidelines on the management of invasive fungal
infection during therapy for haematological
malignancy
171 Treatment of Aspergillosis
174 Practice Guidelines for the Management of
Cryptococcal Disease
175 Guidelines for The Management of Candidiasis
Resource owner
Presenter
/Author
URL link direct to resource
Date Resource
Accessed/
Comments
HPA
http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/124
0294785726
NICE
NICE CKS
http://cks.nice.org.uk/
British Committee on Prentice AG et al http://www.bcshguidelines.com/documents/fungal_infecti
Standards in
on_bcsh_2008.pdf
Haematology
Clin Infect Dis 2008 ; Walsh TJ et al
http://www.idsociety.org/Organism/
46 : 327 -360
Clin Infect Dis 2010 ; Perfect JR
http://www.idsociety.org/Organism/
50 : 291 -322
Clin Infect Dis 2009 ; Pappas PG
http://www.idsociety.org/Organism/
42 : 503 -535
Local guidelines for e.g. management of Pneumocystic
jirovecii
THERAPEUTIC DRUG MONITORING REFERENCES
503 Therapeutic drug monitoring (TDM) of antifungal
J Antimicrob
Ashbee HR et al http://jac.oxfordjournals.org/content/early/2013/12/28/ja
agents: guidelines from the British Society for Medical Chemother (2013)
c.dkt508.full?hwoaspck=true&sid=94fb36c1-9153-44c8Mycology
doi:
b5a5-bddaddddb708
10.1093/jac/dkt508
69
SUPPLEMENTARY RESOURCES
Element 20 - FUNGAL INFECTION - SUPPLEMENTARY RESOURCES
Resource
ID
Name of resource
GENERAL FUNGAL AND ANTIFUNGAL REFERENCES
50 Directed therapy for fungal infections – latest
advances (30 mins)
465 An Official American Thoracic Society Statement:
Treatment of Fungal Infections in Adult Pulmonary
and Critical Care Patients (also covers Pneumocystic
jirovecii)
172 Clinical Practice Guidelines for the Management of
Blastomycosis
173 Practice Guidelines for the Treatment of
Coccidioidomycosis
176 Clinical Practice Guidelines for the Management of
Patients with Histoplasmosis: 2007 Update by the
Infectious Diseases Society of America"
177 Clinical Practice Guidelines for the Management of
Sporotrichosis: 2007 Update by the Infectious
Diseases Society of America
THERAPEUTIC DRUG MONITORING REFERENCES
480 Optimizing antifungal choice and administration (via
TKN / Athens login)
Resource owner
Presenter
/Author
URL link direct to resource
Date Resource
Accessed/
Comments
BSAC
Dr Rosemary
http://bsac.org.uk/events/past-events-2013/bsac-springBarnes
meeting-2013/bsac-spring-meeting-agm-2013-videos/
Am J Respir Crit Care Limper AH et al http://www.thoracic.org/statements/resources/tbMed 2011; 183: 96–
opi/treatment-of-fungal-infections-in-adult-pulmonary128
critical-care-and-sleep-medicine.pdf
Clin Infect Dis 2008 ; Chapman SW
46 : 1801 -1812
Clin Infect Dis 2005 ; Galgiani JN
41 : 1217 -1223
Clin Infect Dis 2007 ; Wheat LJ
45 : 807 -825
http://www.idsociety.org/Organism/
Clin Infect Dis 2007 ; Kauffman CA
45 : 1255 -1265
http://www.idsociety.org/Organism/
Curr Med Research
Opin. 29, Sup 4,
2013, 13–18
http://informahealthcare.com.proxy.knowledgeservices.or
g/doi/pdf/10.1185/03007995.2012.761135
Andes D
http://www.idsociety.org/Organism/
http://www.idsociety.org/Organism/
70
Resources for Element 21 Outpatient parenteral antimicrobial therapy (OPAT)
CORE RESOURCES
Element 21 - OPAT - CORE RESOURCES
Resource
ID
Name of resource
GENERAL OPAT REFERENCES
190 Good practice recommendations for outpatient
parenteral antimicrobial therapy (OPAT) in adults in
the UK: a consensus statement
268
Pharmaceutical Care in OPAT (via TKN) (15 mins)
328 Outpatient Parenteral Antibiotic Therapy (OPAT)
Clinical Vignette (21) (free registration for HCPs) (3
hours)
504 eOPAT website
56 Microbiology - present and future (20 mins)
Resource owner
Presenter
/Author
JAC (2012) 67 (5):
1053-1062.
Chapman ALN et http://jac.oxfordjournals.org/content/67/5/1053.full
al
ASAP Shared Space
Robb F
PAUSE
BSAC
http://www.elib.scot.nhs.uk/SharedSpace/pharmacy/Page
s/RecordDetailFull.aspx?nid=229082&ret=http%3a%2f%2f
www.elib.scot.nhs.uk%2fSharedSpace%2fpharmacy%2fPag
es%2fRecordDetailShort.aspx%3fnid%3d229082%26ret%3d
%2fSharedSpace%2fpharmacy%2fPages%2fIndex.aspx%3
http://www.pause-online.org.uk
BSAC
BSAC
BSAC
Nick Brown
http://e-opat.com/
http://e-opat.com/downloads/
SPECIFIC CONDITIONS OR DRUGS IN OPAT
REFERENCES
55 Role of OPAT in DFI - benefits, drugs, issues (10 mins) BSAC
433 Treating infections in Bone & Joint in acute and OPAT NES
settings
434 Treating infections in Skin & Soft Tissue in acute and NES
OPAT settings (60 mins)
URL link direct to resource
Date Resource
Accessed/
Comments
Paul
http://e-opat.com/downloads/
Chadwick/Claire
McIntosh
Andrew Seaton To be uploaded once recorded
Andrew Seaton http://vimeo.com/79984822 for video
and
http://www.nes.scot.nhs.uk/education-and-training/bydiscipline/pharmacy/about-nes-pharmacy/educational-
71
Element 21 - OPAT - CORE RESOURCES
Resource
ID
Name of resource
189 Development of teicoplanin dosage guidelines for
patients treated within an (OPAT) programme
Resource owner
Presenter
/Author
JAC (2009) 64 (1): Lamont E et al
181-187.
URL link direct to resource
resources/resources-by-topic/infectiousdiseases/antibiotics/treating-infection-in-skin,-soft-tissue,bone-and-joints-for-asap.aspx
for handout
http://jac.oxfordjournals.org/content/64/1/181.full
Date Resource
Accessed/
Comments
SUPPLEMENTARY RESOURCES
Element 21 - OPAT - SUPPLEMENTARY RESOURCES
Resour
ce ID Name of resource
GENERAL OPAT REFERENCES
Practice Guidelines for Outpatient Parenteral
142 Antimicrobial Therapy
444 What are the ideal OPAT agents? (20 mins)
SPECIFIC CONDITIONS OR DRUGS IN OPAT
REFERENCES
445 Cystic Fibrosis & OPAT - What can we learn?
505 Risk factors for failure of outpatient parenteral
antibiotic therapy (OPAT) in infective endocarditis
Resource owner
Presenter
/Author
URL link direct to resource
Date Resource
Accessed/
Comments
Clin Infect Dis ; 2004 Tice AD et al
http://www.idsociety.org/Antimicrobial_Agents/#Outpatie
; 38 : 1651 -1672
nt Parenteral Anti-Infective Therapy (OPAT)
BSAC
DR Robin Howe http://e-opat.com/downloads
BSAC
J Antimicrob
Chemother (2013) 68
(7): 1650-1654.
Iara-Mina
http://e-opat.com/downloads
Sequeios
Duncan CJA et al http://jac.oxfordjournals.org/content/68/7/1650
72