1 Microbiolog .Immunology and Control Course Specifications (2006/2007) Assiut University Faculty of Medicine Department of Microbiology & Immunology Course specifications Course title: MICROBIOLOGY AND IMMUNOLOGY University:Assiut University faculty : faculty of medicine Relevant programme:Bachelor Degree of medicine Department offers the programme: Department of MICROBIOLOGY AND IMMUNOLOGY Department offers the Course : Department of MICROBIOLOGY AND IMMUNOLOGY Scholar year:2006/2007 Date of specitication approval: A- basic lnformation Title : MICROBIOLOGY AND IMMUNOLOGY Code: year/level: 3rdt year hours : Lecture 62 pract: 48 Tutorial/ total 100 AIM OF THE COURSE To educate students about the basic features of general bacteriology, virology and mycology and to provide students with an understanding of the immune system, its protective functions and its role in the patho-physiology of infectious and non-infectious diseases To familiarize students with the common infections and diseases of medical importance, their microbial causes, as well as laboratory diagnosis, treatment, prevention and control of such diseases To enable the students to practice the principles of sterilization and infection control. II. INTENDED LEARNING OUTCOMES (ILOs): Microbiolog .Immunology and Control Course Specifications (2006/2007) 2 A- Knowledge and Understanding a1. Illustrate general bacterial morphology, physiology and genetics a2. explainthe host parasite relationship and microbial pathogens a3. Explain the physiology of the immune system, its beneficial role, as well as its detrimental role in hypersensitivity, autoimmunity and transplant rejection. a4. Describe the morphology, culture, antigenic structure and virulence factors of microorganisms of medical importance. a5. Recognize the most important infectious clinical conditions and outline the diagnosis, treatment, prevention and control of the most likely organisms causing such diseases. a6. Describe the most important methods of decontamination and principles of infection control. a7. Describe the basics of antimicrobial uses and resistance. a8. mention the impact of molecular technology in microbiology and immunology. B- Intellectual Skills b1. Interpret results of microbiological, serological and molecular tests. b2. Interpret microbiological, immunological and molecular reports. b3. Formulate a systematic approach for laboratory diagnosis of common infectious clinical conditions and select the most appropriate and cost-effective tool leading to the identification of the causative organism. b4. Evaluate according to evidence the causal relationship of microbes and diseases. b5. Categorize a microorganism as a bacterium, virus or fungus according to standard taxonomy. b6. Report and appraise a concise scientific activity according to standard scientific thinking and integrity b7. Appreciate the danger of handling and use of infectious agents on community and environment as a part of their ethical heritage. C- Professional and Practical Skills c1. Identify medically important bacteria based on microscopic examination of stained preparations. c2. Perform a Gram stain and a Zichl-Neelsen stain and identify, according to morphology and characteristics, stained preparations. c3. Identify culture media and biochemical tests commonly used for bacterial identification and distinguish positive and negative results. c4. Perform hand wash and control of steam sterilization. D- General and transferable Skills d1. Ability to write reports and essay on the different scientific items in the filed of bacteriology and immunology. d2. Reporting of the facts using printable sheets in the field of bacteriology and immunology. d3. Ability to write a full scientific reports in the field of bacteriology and immunology. d4. Ability to working in groups and team. d5. Ability to use computer and internet to extract information and knowledge. Attitude : By the end of the course, At the end of the course student must be : 1)Aware and capable evaluating the risk of disseminating infections in hospital and community through other cases , carriers or even healthcare workers during manipulating and handling infectious material . 2)Able collaborate with his colleagues in a team work inside the lab, as well as solving problems Microbiolog .Immunology and Control Course Specifications (2006/2007) III. COURSE CONTENTS : A- Topics: Unit (1): General bacteriology: - Introduction - Bacterial morphology - Bacterial structure and taxonomy - Bacterial physiology and metabolism - Bacterial genetics - Antimicrobial therapy - Sterilization and disinfection - Host-parasite relationship Unit (2): Immunology: - Innate immunity - Immunogens and antigens - Cells of the immune response - Acquired immune response "Humoral immunity" - The complement system. - Acquired immune response "cell-mediated immunity" - Protective immunity. - MHC and transplantation immunology - Antigen- antibody reactions. - Hypersensitivity reactions. - Tumor immunology - Tolerance and autoimmunity. - Immuno - deficiency disorders. 3 Microbiolog .Immunology and Control Course Specifications (2006/2007) Unit (3): Systematic bacteriology: - Gram positive cocci (staphylococci, streptococci, and pneumococci) - Gram negative cocci (Neisseria) - Gram positive bacilli non-spore forming (corynebacterium, listeria, actinomyces and lactobacilli). Spore forming (Bacillus and clostridium). - Mycobacteria (T.B and Leprosy) - Gram negative bacilli. o Enteric gram negative bacilli Coliforms, (E.coli, Klebsielle, Salmonella, shigella, proteus and citrobacter) o Pseudomonas, Vibrio, campylobacter and helicobacter o Haemophilus, Bordetella and Brucella. o Yersenia, pasteurella, and francisella. o Legionellae and bacteroides. - Spirochaetes - Mycoplasma and cell wall-defective bacteria. - Rickettsia, coxiella and Chlamydia. Unit (4): General Virology: - General characters & structure – purification of virus - Virus multiplication. - Viral genetics - Virus classification - Pathogenesis of viral infections - Host defense against viral infection - Virus isolation - Diagnosis of viral infection. 4 Microbiolog .Immunology and Control Course Specifications (2006/2007) - Antiviral drugs. Unit (5): Systematic virology: A) DNA viruses (Herpes V., Pox V., Adeno V., papova V.) B) RNA virus: Picorna V., (Entero and Rhino V.) - Rhabdo V. , Toga and Flavi v., Orthomyxo and Paramyxo V. - Retro v. (HIV/HTIV). - Reo V. , corona V., arena V. - Hepatitis viruses. - Oncogenic viruses. - Slow virus. Unit (6): Mycology: A) General mycology. - Structure and classification of fungi. , reproduction of fungi. - Pathogenesis of fungal infection. - Isolation and identification of fungi. - Antifungal drugs. B) Systematic mycology. - Superficial Mycoses (Pityriasis versicolor) - Cutaneous Mycoses (Dermatophytes and candida). - Subcutaneous Mycoses (Mycetoma). - Systemic Mycoses: Pathogenic infection by dimorphic fungi and Opportunistic infection by Candida albicans, Cryptococcus, Aspergillus, rhizopus & mucor). Unit (7): Applied microbiology, nosocomial infection and infection control. 5 Microbiolog .Immunology and Control Course Specifications (2006/2007) 6 B: PRACTICAL CLASSES / SMALL GROUP SESSIONS: b1. Staining by Gram stain an Ziehl-Neelsen stain. b2. Sterilization: autoclave, hot air oven, bacteriological filters. b3. Culture media: commonly used media such as nutrient agar, blood agar, MacConkey's medium, Loffler's medium , Lowenstein-Jensen medium, anaerobic culture media, TCBS, triple sugar iron agar. b4. Biochemical Reactions: sugar fermentation tests, indole test, MR test, VP test, tests for enzyme production (catalase, coagulase, urease). b5. Serological Tests: slide agglutination, tube agglutination, single radial immunodiffusion, double diffusion (Elek's test), toxin-antitoxin neutralization (ASOT). b6. Slides: Staphylococcus, Streptococci, peumococci in tissues, Neisseria, M. tuberculosis, M. leprae, Bacillus anthracis, Clostridiwn tetani, C. diplitheriae, diphtheroids, gramnegative bacilli, Klebsiella in tissues, spirochaetes, Candida albicans, mixtures. b7. Hand Wash and control of steam sterilizer. b8. Case studies: systematic approach, formulation of investigation of work-up and lines of management. b9. Microbiological (serological and molecular) test results, photos and reports for analysis and commenting. b10. Practice of reporting (descriptive and analytical) on demonstrated activities. C: BUREAU HOURS (Tutorial): c1. Focus on host- parasite relationship, causal relationship, critical thinking and scientific integrity. c2. Applied microbiology and safe handling: ethical issues and responsibilities. c3. Reporting and communicating: 2 ways channel. c4. Categorizing according to taxonomy and self learning. IV. TEACHING & LEARNING METHODS: A: Facilities used for teaching this course include: a1. Lecture halls a2. Data shows & computer assistance a3. Laboratories (with sinks) a4. Small group areas (rooms) equipped with computer assistance a5. Microscopes B: METHODS USED: b1. Lecture b2. Practical class b3. Small group discussion with case study and problem solving b4. Quiz b5. Micro assignment b6. Bureau hour (Tutorial) Microbiolog .Immunology and Control Course Specifications (2006/2007) 7 C: METHODS FOR DISABLED STUDENTS: No special arrangements are available D: TEACHING PLAN: d1. Lecture ( fu lly illustrated with drills): Students are divided into two large groups (A and B) for lectures. The lecture halls are located on the second floor of the Medical Education Building. One-hour -lectures are held twice weekly (Saturday: 10:00-11:00, and Sunday: 9:00-10:00). Lectures are given throughout the academic year. d2. Practical class and small group discussions: Students arc divided into 10 groups. Each group has one practical class per week throughout the academic year (11:30-1:00 or 1:30-3:00), Students of each group are first divided into two subgroups for explanation of practical class and revision of relevant theoretical material. Each sub-group is further subdivided into two (total of four small groups) for practical demonstration and discussion. • Quiz (formative) d3. Out of practical class hours: • Micro assignment • Bureau hour (Tutorial) V. STUDENT ASSESSMENT : A: ATTENDANCE CRITERIA: Students should attend no less than 75 % of practical classes and/or small group sessions as an essential prerequisite to be legible for the final exams. B: ASSESSMENT TOOLS: Written Examination: Assessment of knowledge and understanding and intellectual skills (a1-a8,b1-b7) Oral Examination: Assessment of knowledge and understanding outcomes and intellectual sk ills(a1- a8 ,b1-b 7) Practical Examination: A. Assessment of practical skills (c1-c4.d1-d5) B. Intellectual skill (b1-b7) a. Station b. Objective Structured Test (OST) c. Photos d. Report Quiz Micro-report 8 Microbiolog .Immunology and Control Course Specifications (2006/2007) C: ASSESSMENT SCHEDULE: • Mid-year Examination: held for all students at end of first term (January) • Final Examination: held for all students at end of second term (May-June) D: GRADING SYSTEM: Examination: Marks allocated Mid-year Examination Final Examination Written Written Oral Practical 40 marks 100 marks 20 marks 40 marks 15 Stations 5 OST 5 Photos 5 Report 5 Quiz 5 Micro re port 200 marks TOTAL o The minimum passing score is 100 marks provided at least 30 marks are obtained in the final written examination. o Passing grades are: EXCELLENT >85%, VERY GOOD 75- <85%, GOOD 65- <75% and FAIR 60- <65%. E: EXAMINATION DESCRIPTION: Examination Mid-year Exam. Type 1 . Written Description Marks A 2-hour written paper composed of short essay - 40 marks type questions and MCQs Final Exam. 2. Written A 2-hour written paper composed of short essay- 100 marks type questions, MCQs and Case study 3. Practical 15 spots including slides, culture media, biochemical reactions, serological tests and instruments (descriptive structured) Hand wash, Gram stain, Ziehl...etc. According to check list 4. OST 5. Photos 5 marks 6. Report 5 marks 7. Quiz Focus subject 5 marks 8. Oral One oral examination station with 2 staff members (10-15 minutes: 4-5 questions) Micro-assignment 20 marks 9. Report TOTAL 1 5 marks (1 mark for each spot) 5 marks 5 marks 200 marks Microbiolog .Immunology and Control Course Specifications (2006/2007) 9 VI. LIST OF TEXT BOOKS AND REFERENCES: A: BASIC MATERIALS: • Department theoretical books and practical manual: available for students to purchase from different bookshops at the faculty • Overhead projections, slides and computer presentations used during leaching • Microscope slides, laboratory instruments and items B: SUGGESTED MATERIALS: • Jawetz, Melnick and Adelberg's Medical Microbiology • Janeway and Travers Immunobiology: The immune system in health and disease. Course Schedule Learning objectives: (A) Knowledge and understanding Unit (1): General bacteriology: - Introduction: a1 recognize the different groups of M.O. a2 describe the difference between prokaryotes and eukaryotes. - Bacterial morphology: a1 illustrate different shapes and arrangement of bacteria. a2 recognize the different methods of staining and identification of bacterial shape and arrangement. - Bacterial structure and taxonomy: a1 describe and illustrate the structure of bacteria. a2 understand the function of each part in bacterial cell. a3 mention the criteria for classification of bacteria. - Bacterial physiology and metabolism: a1 illustrate the growth curve of bacteria. a2 describe the significance of growth curve. a3 recognize the requirements for bacterial growth. a4 recognize the environmental factors affecting bacterial growth. a5 describe bacterial anabolism and catabolism. Microbiolog .Immunology and Control Course Specifications (2006/2007) a6 describe the sources of metabolic energy. a7 identify the methods of isolation of M.O. in pure culture. - Bacterial genetics: a1 describe bacterial chromosome and replication. a2 recognize gene expression in bacteria. a3 recognize bacterial plasmid, types and function a4 describe transposons, and insertion sequences a5 recognize bacterial variation and its types. a6 illustrate types and methods of gene transfer between bacteria. a7 define types of bacterial mutation. a8 recognize and illustrate the steps of gene cloning. a9 recognize the applications of recombinant DNA technology - Antimicrobial therapy: a1 mention the types of action of chemotherapeutics. a2 mention the range of action of chemotherapeutics. a3 describe the mechanism of action of chemotherapeutics. a4 describe the mechanism of resistance to chemotherapeutics. a5 understand and mention the origin of resistance. a6 mention the complications of antimicrobial chemotherapeutics. a7 mention the clinical uses of antimicrobial chemotherapeutics. - Sterilization and disinfection: a1 mention the different methods of sterilization of and disinfection a2 recognize the uses of each method of sterilization and disinfection a3 recognize the tests of efficiency of autoclave - Host-parasite relationship: a1 define saprophytic and parasitic bacteria a2 define the pathogens, commensals and opportunistics 10 Microbiolog .Immunology and Control Course Specifications (2006/2007) a3 describe the infection process a4 describe the factors which govern disease production a5 define virulence and pathogenicity. a6 describe the virulence factor of bacteria a7 recognize the difference between endotoxins and exotoxins. Unit (2): Immunity - Innate immunity a1 define innate immunity. a2 describe the 1st and 2nd lines of natural defense. a3 recognize the factors that modify innate immunity. - Immunogens and antigens: a1 define hapten, antigen, immunogen and epitopes. a2 recognize the factors influencing immunogenicity. a3 recognize the antigen-antibody binding a4 list the types of antigens - Cells of the immune response: a1 describe B and T lymphocytes, their distribution, stimulation, surface markers and functions. a2 illustrate the TCR. a3 describe the role of macrophage and NK cells. a4 recognize the ways of acquiring specific immunity. - Acquired immune response "humoral immunity" a1 describe the Ab production and clonal selection theory a2 illustrate the structure of Ig (Ab). a3 recognize the types and characteristics of Ig class a4 recognize Ig gene rearrangement and Ab diversity 11 Microbiolog .Immunology and Control Course Specifications (2006/2007) a5 mention the biological function of Ab. a6 describe the primary and 2ry immune response a7 illustrate and describe monoclonal Ab production and its uses. - The complement system: a1 Describe activation of complement system by classical and alternative pathways. a2 recognize the regulation of complement system a3 mention the biological activities of complement system. - Acquired immune response "cell-mediated immunity": a1 recognize the role of CMI. a2 recognize the characters of CMI. a3 describe the stages of CMI response. a4 define super antigens. a5 mention the different types of cytokines and their function and uses. - Protective immunity: a1 describe anti bacterial immunity. b2 describe antiviral immunity. - MHC and transplantation immunology : a1 illustrate the classes of MHC. a2 recognize the significance of MHC. a3 describe the types of grafts. a4 describe the type and mechanism of graft rejection. a5 recognize how to prevent graft rejection. - Antigen- antibody reactions : a1 recognize the different types of antigen-antibody reactions a2 recognize the applications of serological tests in diagnosis. 12 Microbiolog .Immunology and Control Course Specifications (2006/2007) - Hypersensitivity reactions: a1 recognize the different types of hypersensitivity reaction. a2 recognize the mechanism, and clinical types of each type. a3 recognize the diagnosis and management of hypersensitivity reactions. - Tumor immunology: a1 mention tumor associated antigens. a2 describe the immune response to tumor antigens. a3 describe the approaches to cancer immunotherapy a4 mention some tumor markers - Tolerance and autoimmunity: a1 describe the mechanism of autotolerance. a2 mention the factors affecting the induction of tolerance a3 recognize the aetiology of autoimmune diseases. a4 recognize the mechanism of tissue damage in autoimmune dis. a5 mention the diagnosis and management of autoimmune dis. - Immunodeficiency disorders: a1 recognize the causes of primary and secondary I.D. a2 mention how to asses immune competence Unit (3): Systematic bacteriology A1 describe the morphology, culture and biochemical reaction of the M.O. A2 describe the antigenic structure and virulence factor of the M.O. A3 describe the pathogenesis and mode of transmission of the diseases produced by the M.O. a4 recognize the most important infectious clinical condition and outline the diagnosis, treatment, prevention and control of these conditions. 13 Microbiolog .Immunology and Control Course Specifications (2006/2007) 14 Unit (4): General Virology a1 recognize the general characters of viruses a2 describe virus size, shape , structure and chemical composition. a3 mention the methods of virus purification a4 mention the basis of virus classification. a5 recognize the steps of virus replication. a6 recognize virus interference and recombination a7 recognize the pathogenesis and host defense in virus infections. a8 recognize the method of virus isolation and other laboratory procedures for diagnosis of viral infections. a9 mention the different types of antiviral drugs, their mechanism of action and uses. Unit (5): Systematic Virology: a1 recognize the general characters of each family a2 mention the important diseases caused by the virus. A3 recognize the pathogenesis and mode of transmission of viral diseases. A4 outline the diagnosis, treatment, prevention and control of viral diseases. Unit (6): Mycology - General Mycology a1 describe the structure, organization and reproduction of fungi. a2 recognize the pathogenesis of fungal infections and virulence factors. a3 recognize the method of isolation and identification of fungal disease. a4 mention the anti fungal drugs and their uses. - Systematic mycology: a1 mention the general characters of each type of infection and the causative fungi. A2 describe the diagnosis and treatment of each type of fungal infection. Microbiolog .Immunology and Control Course Specifications (2006/2007) 15 Unit (7): Applied microbiology: a1 recognize the most important infectious clinical conditions and enumerate the most common M.O. causing such infection. A2 outline the diagnostic tests, prevention and control of the most likely M.O. causing such infection. A3 describe the most important methods of decontamination and principles of infection control. (B) Intellectual skills : Unit (1): General bacteriology: Student should be able to: B1 categorize a microorganism as bacterium, virus or fungus B2 compare between prokaryotes and eukaryotes. B3 compare between the structure of cell wall in gram positive and gram negative bacteria. B4 correlate between the structure of bacteria and its function. B5 Interpret the antibiotic sensitivity test and choose the most effective one against the isolated microorganism. B6 appreciate the danger of infectious agents on community and environment. Unit (2): Immunology: b1 compare between B and T lymphocytes. b2 compare between antibodies and interferon. b3 design experiments to prove the characters of the immune system. b4 compare between the primary and secondary immune response. b5 compare between the antigen and super-antigen. b6 categorize cytokines according to their function and source. b7 correlate between the classes of MHC and their function. b8 Interpret the results of serological tests. Microbiolog .Immunology and Control Course Specifications (2006/2007) 16 Unit (3): Systematic bacteriology: B1 interpret the results of microscopic examination and cultural characteristics of different M.O. for identification of such organisms. b2 interpret the results of biochemical reactions used for identification and classification of bacteria. b3 interpret the results of serological tests used for identification of M.O. b4 formulate systemic approach for laboratory diagnosis of the common bacterial infections and select the most appropriate and cost- effective tool for identification of the causative M.O. b5 categorize the bacteria according to the biochemical reactions. b6 categorize bacterial vaccines according to their type & method of preparation. Unit (4): General virology: b1 Categorize viruses according to their size, shape and chemical structure. b2 formulate systemic approach for laboratory diagnosis of common viral infection. b3 compare between replication of DNA viruses and RNA viruses b4 compare between the different types of interferon Unit (5): Systematic virology: b1 differentiate between the general characters of each family of viruses. b2 categorize viruses according to the diseases produced and organs affected. b3 formulate a systemic approach for laboratory diagnosis of common viral infections and select the most appropriate and cost effective tool for identification of the causative virus. b4 categorize viral vaccines according to their type and method of preparation. Unit (6): Mycology: b1 compare between the characters of fungi and bacteria. b2 categorize fungi according to the site of infection and type of reproduction (spores). b3 formulate a systemic approach for laboratory diagnosis of the common fungal Microbiolog .Immunology and Control Course Specifications (2006/2007) 17 infections. Unit (7): Applied microbiology: b1 formulate a systemic approach for laboratory diagnosis of the common infections and select the most appropriate and cost-effective tool for identification of the causative microorganism. (C) Practical skills: General bacteriology: Unit (1): Students should be able to: c1 use the light microscope c2 perform Gram stain, Zheil –Neelsen stain and other special stains. c3 identify the medically important M.O. based on microscopic examination of stained preparations. c4 identify the commonly used methods of sterilization. c5 identify the culture media used for microbial isolation. c6 identify the different cultured characteristics of important M.O. on the culture media. c7 perform isolation of bacteria in pure culture. Unit (2): Immunology: Students should be able to : c1 identify the commonly used serological tests for diagnosis of infection. Unit (3): Systematic bacteriology : c1 Perform gram stain, zheil –neelsen stain and other special stains for identification of the common M.O. c2 Identify the medically important M.O. based on microscopic examination. c3 identify the medically important M.O. based on cultural characteristics and biochemical reactions. Microbiolog .Immunology and Control Course Specifications (2006/2007) 18 c4 identify the serological tests used for diagnosis of the common microbial infections and differentiate between +ve and negative results. c5 identify the different methods used for anaerobic cultivation. Unit (4): Unit (5): Unit (6): Mycology: c1 identify the medically important fungi based on microscopic examination of stained preparation and cultural characteristics. Unit (7): Applied microbiology c1 collection and examination of pathological materials, perform stained films from the common pathological samples and identify the M.O. by microscopic examination. D- General and transferable Skills d1. Ability to write reports and essay on the different scientific items in the filed of bacteriology and immunology. d2. Reporting of the facts using printable sheets in the field of bacteriology and immunology. d3. Ability to write a full scientific reports in the field of bacteriology and immunology. d4. Ability to working in groups and team. d5. Ability to use computer and internet to extract information and knowledge. Attitude : By the end of the course, At the end of the course student must be : 1)Aware and capable evaluating the risk of disseminating infections in hospital and community through other cases , carriers or even healthcare workers during manipulating and handling infectious material . 2)Able collaborate with his colleagues in a team work inside the lab, as well as solving problems 19 Microbiolog .Immunology and Control Course Specifications (2006/2007) Course schedule Topics 1-General bacteriology Introduction Morphology Structure and taxonomy Physiology and metabolism Genetics Antimicrobial therapy Sterilization and disinfection Host/Parasite Relationship 2- Immunology Innate immunity Immunogens antigens Cells of the immune response Humoral immunity The complement system Cell mediated immunity Protective immunity MHC & transplantation Ag-Ab reactions Hypersensitivity Tumor immunology Tolerance and autoimmunity Immunodeficiency 3- Systematic bacteriology Gram +ve cocci Gram –ve cocci Gram +ve bacilli Mycobacterium Gram –ve bacilli Spirochaetes Mycoplasma Teach. Method Covered ILOs Lecture Lecture Lab. Lecture Lecture Lab. Lecture Lecture Lab. Lecture Lab. Lecture A1, 2 /B1,2 A1,2 /B3 C1,2 /B3 A1-3/B4 A1-7 C5-7 A1-9 A1-7 B5 A1-3 B6/C4 A1-7 1 1 2 1 1 2 2 2 2 2 2 1 Lecture Lecture Lecture A1-3 A1-4 A1-4/B1 ½ ½ ½ Lecture Lecture Lecture Lecture Lecture Lecture lab. Lecture Lecture Lecture A1-7/B4 A1-3 A1-5/B2, 5,6 A1,2/B3 A1-5 /B7 A1, 2 B8, C1 A1-3 A1-4 A1-5 ½ ½ 1 ½ 1 1 4 1 1 ½ Lecture A1, 2 ½ Lecture Lab. Lecture Lab. Lecture Lab. A1-4/B4, 5 C2, 3,4 /B1, 2 A1-4/B4-6 C2, 3, /B1, 2 A1-4/B4-6 C1, 2,3,5/B1, 2 A1-4/B4-6 C1-3/B1, 2 A1-4/B4-6 C1-4/B1-3 A1-4/B4 C1,2,4 /B1,3 A1-4/B4 2 4 2 2 4 4 Lecture Lab. Lecture Lab. Lecture Lab. Lecture Hours 2 2 8 6 2 2 1 Time/whom Microbiolog .Immunology and Control Course Specifications (2006/2007) Rickettsia & Chlamydia 4- General Virology 5- Systematic Virology 6- Mycology General Systematic 7- Applied microbiology Lecture Lecture Lecture A1-4/B4 A1-9/B1-4 A1-4/B1-4 2 3 8 Lecture Lab. Lecture Lecture Lab. A1-3 C1 A1, 2/B2, 3 A1-3/B1 C1 1 2 2 3 6 20