Dr. Nida Ambreen Curriculum Vitae Dr. NIDA AMBREEN Post Doctoral Fellow (FFTF International Scholarship) United Kingdom Assistant Professor Federal Urdu University of Arts Science, and Technology, Karachi, Pakistan Scientific Proof Reader Journal of the chemical Society of Pakistan (March 2009 - March 2010) Postal Address: 315-HEJ Research Institute of Chemistry International Center for Chemical and Biological Sciences University of Karachi, Karachi-75270 Cell # 0092-300-3670485 Personal Data Name: NIDA AMBREEN Date of Birth: July 26, 1979 Nationality: Pakistani Gender; Female Marital Status: Single E-mail: nidahej@yahoo.com, nida_mishi2002@yahoo.com AREAS OF INTEREST General Synthetic Organic Chemistry, Bioorganic and Medicinal Chemistry, Green Chemistry, Organometallic Chemistry, Microwave-assisted Organic Synthesis, Microreactor Flow Chemistry 1/14 Dr. Nida Ambreen PROFESSIONAL EXPERIENCE Present Positions: Postdoctoral Fellow: Prof. Dr. Thomas Wirth, School of Chemistry, Cardiff University, United Kingdom August, 2012- Present Postdoctoral Fellow: Prof. Dr. Khalid. M. Khan, H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi October, 2010- July, 2012 Assistant Professor: Federal Urdu University of Arts Science, and Technology, Karachi, Pakistan, Karachi-75300, August 2010-2011 Continue as visiting assistant professor Till April 2012. Courses Taught at University as an Assistant Professor: I have experience of Teaching and Research on the university level as a faculty in Federal Urdu University of Arts Science and Technology Karachi Pakistan. I have taught the following courses MS/PhD: Microwave-Assisted Organic Synthesis, C-C Single, Double, and Triple Bond Formation, Organo-Metallic Chemistry. MSc/BSc: Pharmaceutical Chemistry of Chemistry, Carbonyl Organic Compounds, Nitrogenous Compounds, Retrosynthesis, Cycloaddition Reactions, Rearrangement and Name Reactions. Scientific Proof Reader: Journal of Chemical Society of Pakistan. March 2010- March 2011 Reviewer: i) Journal of the Chemical Society of Pakistan ii) HEC National Research Grant Research Fellow: With Prof. Dr. Khalid. M. Khan,, Co director, H. E. J. Research Institute of Chemistry, University of Karachi, International Center for Chemical and Biological Sciences, Karachi-75270, Pakistan. October 2002 - June 2010, The research topic was “Synthesis of Bioactive Chromones and Related Heterocyclic Compounds and Studies Towards the Synthesis of Diethyl 2-(3-oxo-3-(2-oxooxazolidin-3-yl)-1phenylpropylidene) malonate,” submitted Ph. D. thesis and took Ph. D. examination. Total Impact Factor: 45 2/14 Dr. Nida Ambreen ACHIEVEMENTS MERITS AND SCHOLARSHIPS Finished my PhD in July 2010 entitled “Synthesis of Bioactive Chromones and Related Heterocyclic Compounds and Studies Towards the Synthesis of Diethyl 2-(3-oxo-3-(2-oxooxazolidin-3-yl)-1-phenylpropylidene) malonate” under the supervision of Prof. Dr. Khalid Mohammed Khan. Awarded HEJ Research Scholarship. Research Productivity Award 2011 (Ministry of Science Government of Pakistan & Pakistan Council of Science (Received in 2012). Research Productivity Award 2010 (Ministry of Science Government of Pakistan & Pakistan Council of Science (Received in 2011). Recipient of a Prestigious Scholarship through Faculty for the Future Program (FFTF) from Schlumberger Foundation of France and Netherland, during August 2012- July 2013. The time period will be spent at the School of chemistry, Cardiff University, U.K. under the guidance of Prof. DR. Thomas Wirth on the research of Subcritical Water as Green Solvent in Microreactor Chemistry. Recipient of a Prestigious Scholarship through International Research Support Initiative Program (IRSIP) from Higher Education Commission of Pakistan during April 2007. The time period was spent at the Department of chemistry and Chemistry Research Laboratories, Oxford University, U.K. under the guidance of Prof. DR. Mark. G. Moloney on the successful synthesis of Diethyl 2-(3-oxo3-(2-oxooxazolidin-3-yl)-1-phenylpropylidene) malonate under Microwave assisted organic synthesis. Before that, in March 2007, I visited the University of Florence, Italy where I got some training in the fields of Carbonic Anhydrase Enzyme Activity. Qualified four full fledge advance courses in organic chemistry at HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi (Pakistan) securing excellent grades in each. 3/14 Dr. Nida Ambreen First Prize winner in Poster competition 9th International and 20th National Chemistry Conference, March 14-16, 2011, Karachi Third Prize winner in chemistry modal in science exhibition, Federal Urdu University, Karachi 1998 QUALIFICATIONS I have qualified Eight full fledge advance courses in organic chemistry at H. E. J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi (Pakistan) securing excellent grades in each. Brief outline of the courses is as follows; 1) CHEM-701 (Physical Organic Methods) Contents of this course include IR, UV, CD-ORD, Mass spectrometry, NMR spectroscopy, separation techniques, X-ray crystallography, molecular mechanics, structure determination of proteins and peptides, genetic engineering and how to search the literature. 2) CHEM-702 (Structure and Reactivity) This course includes the static and dynamic stereochemistry, stereoelectronic effects of organic compounds, study and description of organic reaction mechanisms, mechanisms of polar additions and elimination reactions, photochemistsry, aromaticity and antiaromaticity, pericyclic reactions, HSAB theory, structure and reactivity of carbocations, reactive intermediates, free-radicals and molecular rearrangements. 3) CHEM-703 (Synthesis-I) Designed to cover a broad range of organic reactions that includes oxidation, reduction of carbonyl compounds and other functional groups, C-C bond forming reactions (Aldol reaction, Manich reaction, Wittig reaction, Suzuki coupling, Stille coupling, Heck reaction, Sonogashira coupling, Negishi coupling, Julia olefination, Peterson olefination etc), also reactions forming C-C bond by the use of organoboron, organosilicon and organotin compounds, aromatic electrophilic and nucleophilic substitutions, protecting groups and syntheses via pericyclic reactions and organometallic compounds of the group 4/14 Dr. Nida Ambreen I, II and III. Finally the stereochemical considerations of all the mentioned reactions have been studied extensively. 4) CHEM-704 (Synthesis-II) This course serves to provide a broad understanding of the contemporary art of organic synthesis, planning and execution of multi-step synthesis, functional group interconversions and newer methods for the preparation of different functional groups, asymmetric electrophilic additions to C-C multiple bonds, logic of chemical synthesis, logical approach to asymmetric synthesis, natural products and their biosynthesis, introduction to solid phase and combinatorial synthesis along with green chemistry. During this course following natural products have been studied extensively; Synthetic studies on Longifolene, Taxol, Juvabione, Epothilones A, B, C and D, Callystatin A, Tetrodotoxin, Antascomicin B, Colchicine, and Prelog-Djerassi lactone. Aspects in remote stereocontrol has also been studied extensively, especially the use of chiral allyl stannanes, use of Claisen, Wittig rearrangements, and Iron carbonyl complexes in acyclic polyene stereocontrol. 5) CHEM-801 Modern Mass Spectrometry and Solving Mass Spectrometric Problems. This course covers all the advance techniques in Mass spectrometry including EI MS, FAB, EI, ESI, FD, MALDI etc., with all the instrumentation and problem solving practices. 6) CHEM-805 Other Special Courses in Biochemistry and other Branches of Chemistry by leading foreign and Pakistani Speakers. 7) CHEM-806 Recent Advances in Chemical Sciences, Lectures by leading experts. 8) CHEM-807 Research Project Writing and Presentations by Scholars 5/14 Dr. Nida Ambreen Academics Qualified GRE Subjective in December 2005 by securing 700/990 (percentile 57) Degree Subjects Educational Institution Year Ph. D. Organic HEJ Research. Institute of 2010 1st Div Chemistry Chemistry, University of Karachi, Karachi, Pakistan MSc Chemistry Karachi University, Karachi, 2002 1 Div (Organic) Pakistan BSc Chemistry, Karachi University, Karachi, 2nd Div Biochemistry, Pakistan st 1998 Microbiology FSc Pre-Medical. 2nd Div Matric Pakistan Science 1st Div References: Karachi Inter Board, Karachi, 1996 Karachi Metric Board, 1994 Karachi, Pakistan 1) Prof. Dr. Khalid M. Khan HEJ Research Institute of Chemistry International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270 Email: hassaan2@super.net.pk Khalid.khan@iccs.edu 2) Prof. Dr. Viqar Uddin Ahmad HEJ Research Institute of Chemistry International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270 Email: vuahmad@yahoo.com 6/14 Dr. Nida Ambreen 3) Prof. Dr. Abdul Malik HEJ Research Institute of Chemistry International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270 Email: abdul.malik@iccs.edu COMPUTER KNOWLEDGE Can handle Microsoft Office Applications and Chemistry soft wares like Chemdraw/Chemwindow CONFERENCE ATTENDED A number of International and National Symposia, Conferences, Seminar, Workshops and Trainings were attended and presented posters some are as under. 1. 2. 3. 4. 5. 6. 7. 8. 9th International and 20th National Chemistry Conference, March 14-16, 2011, Deprtmant of Chemistry University of Karachi, Karachi, Pakistan. 12th International Symposium on Natural Product Chemistry, October 29November 01, 2010, H. E. J. Research Institute of Chemistry University of Karachi, Pakistan. 8th International and 20th National Chemistry Conference, February 15-17, 2010, Deprtmant of Chemistry Quid-i-Azam University, Islamabad, Pakistan. 19th National Chemistry Conference, Department of Chemistry, Kohat University of Science and Technology, Kohat, June 9-11, 2009 (At Peshawar University Summer Campus Baragali), Pakistan. One Day Workshop Collabortion with HEC-BC (British Council), May 16, 2009, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan. 3rd National Seminar, “Intellectual Right to Magic Methods” April 15-16, 2008, at Pearl Continental Hotel, Lahore organized by Patent Advisory Cell, PCSIR, Karachi, Pakistan. 11th International Symposium on Natural Product Chemistry, October 29November 01, 2008, H. E. J. Research Institute of Chemistry University of Karachi, Pakistan. 18th National Chemistry Conference, February 25-27, 2008, Institute of Chemistry University of the Punjab Lahore, Pakistan. 7/14 Dr. Nida Ambreen 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 9th International Symposium on Protein Function Relationship, January 11-14, 2007, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Karachi. First IBRO School of Neuroscience March 26-30, 2007, Dr Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical & Biological Sciences, University of Karachi, Pakistan. Workshop on New Instrumentation and Application of Mass Spectrometry August 7-9, 2006, H. E. J. Research Institute of Chemistry University of Karachi, Pakistan. 10th International Symposium on Natural Product Chemistry, January 06-09, 2006, H. E. J. Research Institute of Chemistry University of Karachi, Pakistan. 6th International and 16th National Chemistry Conference, April 4-6, 2006, Department of Chemistry, Bahauddin Zakaria University, Multan, Pakistan: Theme “Quality of Life and Chemical Sciences”. In-Service Training Workshop “Chromatography and Statistics in Chemistry” December 26, 2004-January 9, 2005. National Core Group in Chemistry University of Sind, Jamshoro, Pakistan. 8th International Symposium on Protein Structure Function Relationship Januray 7-10, 2005 & Workshop on Characterization of Protein Jan 12-18, 2005 H. E. J. Research Institute of Chemistry University of Karachi, Pakistan 9th International Symposium on Natural Product Chemistry, January 10-13, 2004. H. E. J. Research Institute of Chemistry University of Karachi, Pakistan Workshop on Application of Modern Spectroscopic Techniques In Chemical Sciences December 6-23 2004. National Core Group in Chemistry H. E. J. Research Institute of Chemistry University of Karachi, Pakistan 5th International and 15th National Chemistry Conference November 24-27, 2004. Department of Chemistry Quai-i-Azam University, Islambad, Pakistan. 9th International Symposium on Natural Product Chemistry, January 10-13, 2004. H. E. J. Research Institute of Chemistry University of Karachi, Pakistan 7th International Symposium on Protein Structure Function Relationship January 20-24, 2003, Karachi, Pakistan. 4th International and 14th National Chemistry Conference, May 16-18, 2004, PCSIR Laboratories Complex Lahore, Pakistan, Theme “Quality through Innovative Chemistry.” POSTER PRESENTATION Poster presentation in 9th International and 20th National Chemistry Conference on Structure-Based Design, Synthesis and Biological Evaluation of Selective ß-Glucuronidase Inhibitors, in Karachi, March 14-16, 2011. (First Prize Winner in Poster Competition out of 84 posters) 8/14 Dr. Nida Ambreen Poster presentation in 19th National Chemistry Conference on studies Towards The Synthesis of Diethyl ethylidine malonates Via Microwave-Assisted Synthesis in Islamabad, June 09-12 2009. Poster presentation in 9th International symposium on Natural Product Chemistry on Chromone and Their Pharmacological Activities in Karachi-Pakistan, January 2004 Poster presentation in 10th International symposium on Natural Product Chemistry on Microwave assisted synthesis of Coumarines amides and Their Pharmacological Activities in Karachi-Pakistan, January 2006 PROFESSIONAL MEMBERSHIPS The Chemical Society of Pakistan (Life Member) REVIEWR HEC Research Projects The Journal of the Chemical Society of Pakistan PROJECTS FUNDED BY NATIONAL FUNDING AGENCIES One project is recently been completed successfully which is funded by the Higher Education of Pakistan. SUPERVISION OF RESEARCH STUDENTS One (1) Msc Thesis Completed. Two (2) M. Phil. and Ph.D. students are currently carrying out their research work at HEJ Research Institute Pakistan. RESEARCH PUBLICATIONS Kindly see attached list of Publication 9/14 Dr. Nida Ambreen LIST OF PUBLICATIONS OF Dr NIDA AMBREEN 1. An Efficient Eco-Friendly Synthesis of Indole-Mannich Base. Khalid Mohammed Khan, Fazal Rahim, Nida Ambreen, Muhammad Taha, Sarosh Iqbal, Syed Moazzam Haider, And Shahnaz Perveen. J. Chem. Soc. Pak., 2012, 34, 748-757. 2. Asymmetric Induction via Metalation of Succinic Esters and Amide Using S(+) Menthol and R(+) 1-Phenylethylamine as Chiral Auxiliaries. Auj e Sana, Sher W. Khan, Nida Ambreen, Muhammad Arfan, Javid H. Zaidi, Khalid M. Khan, Shahnaz Perveen and Ghulam A. Miana. Lett. Org. Chem., 2012, 9, 632-638. 3. Synthesis, characterization and biological screening of sulfonamides derived form 2-phenylethylamine. Aziz-ur-Rehman, Sumbel Afroz, Muhammad Athar Abbasi, Wajeeha Tanveer, Khalid Mohammed Khan, Muhammad Ashraf, Irshad Ahmad, Iftikhar Afzal and Nida Ambreen. Pak. J. Pharm. Sci., 2012, 25, 2012, 809-814. 4. Synthesis and structural characterization of some lipoxygenase-inhibiting O-arylO-phenyl carbonates. M. A. Abbasi, F. M. Khan, Aziz-ur-rehman, T. Muhmood, K. M. Khan, M. Ashraf, I. Afzal and N. Ambreen. Biosci. Res., 2012, 9, 30-35, 5. 5-Chloro-2-(3,4,5-trimethoxyphenyl)-1,3-benzothiazole Sammer Yousuf, Shazia Shah, Nida Ambreen, Khalid M. Khan and Shakil Ahmad. Acta Cryst, 2012, E68, o3057. 6. 2-(5-Chloro-1,3-benzothiazol-2-yl)-4-methoxyphenol. Sammer Yousuf, Shazia Shah, Nida Ambreen, Khalid M.Khan and Shakil Ahmad. Acta Cryst, 2012, E68, o2877. 7. 6-Methyl-4-oxo-4H-chromene-3-carbaldehyde. Sammer Yousuf, Asma Mukhtar, Nida Ambreen, Syed Muhammad Saad and Khalid M. Khan. Acta Cryst, 2012, E-68, o2920. 8. 5-Chloro-2-phenyl-1,3-benzothiazole. Sammer Yousuf, Shazia Shah, Nida Ambreen, Khalid M. Khan and Shakil Ahmed. Acta Cryst, 2012, E-68, o2799. 9. 8-[(2-Hydroxyphenyl)imino]-3,5a,9-trimethyl-3a,4,5,5a,8,9b-hexahydronaphtho[1,2-b]furan-2(3H)-one. Sammer Yousuf, Mohammad Younus, Nida Ambreen, Khalid M. Khan and Ghulam A. Miana. Acta Cryst, 2012, E-68, o2158. 10. 1-(3-Methoxyphenyl)-2-(phenylsulfonyl)-1-ethanone. Sammer Yousuf, Sarosh Iqbal, Nida Ambreen and Khalid M. Khan. Acta Cryst, 2012, E-68, o2568. 10/14 Dr. Nida Ambreen 11. 8-[(2-Hydroxyphenyl)imino]-3,5a,9-trimethyl-3a,4,5,5a,8,9b-hexahydronaphtho[ 1,2-b]furan-2(3H)-one. Sammer Yousuf, Syed M. Younas, Nida Ambreen, Khalid M. Khana and Ghulam A. Miana. Acta Cryst, 2012, E-68, o2158. 12. 6-Nitrobenzimidazole Derivatives: Potential Phosphodiesterase Inhibitors: Synthesis and Structure-Activity Relationship. Khan, K. M. ZarbadShah, Ahmad, V. U. Ambreen, N. Khan, M. Taha, M. Rahim, F. Noreen, S. Perveen, S. Choudhary, M. I. and Voelter, W. Bioorganic and Medicinal Chemistry, 2012, 20(4),1521-1526 13. Synthesis and Antimicrobial Activity of Chiral Imides from Diacetyl-L-Tartaric Acid Anhydride and Different Amino Acids. Sher Wali Khan, Sara Naz, Javid Hussain Zaidi, Nida Ambreen, Khalid Mohammed Khan, Shahnaz Perveen, and Ghulam Abbas Miana. Journal of Pharmacy Research, 2012, 5, 646-650. 14. Schiff Bases of Thiazole as Antibacterial and Antifungal Agents. Khalid Mohammed Khan, Nida Ambreen, Aneela Karim, Sumayya Saied, Afroz Aymon, Aqeel Ahmed, and Shahnaz Perveen. Journal of Pharmacy Research, 2012, 5, 651-656. 15. Synthesis, antioxidant and carbonic anhydrase inhibitory potential of Schiff bases of thiazoles. Khalid Mohammed Khan, Aneela Karim, Sumayya Saied, Nida Ambreen, Muhammad Saleem, Afroz Aymn, Shahnaz Perveen, Aqeel Ahmad, and M. Iqbal Choudhary. Journal of Pharmacy Research, 2012, 5, 661-663. 16. Synthesis of benzoxazoles derivatives: Antiglycation activity. Khalid Mohammed Khan, Aneela Karim, Nida Ambreen, Sumayya Saied, Saima Rasheed, Shahnaz Perveen, and M. Iqbal Choudhary. Journal of Pharmacy Research, 2012, 5, 664665. 17. Synthesis, antibacterial and antifungal evaluation of norfloxacin derivatives. Khalid Mohammed Khan, Rakhshinda Siddiqui, Nida Ambreen, Najma Sultana, Saima Tauseef, Aqeel Ahmad, and Shahnaz Perveen Journal of Pharmacy Research, 2012, 5, 666-671. 18. Acyl Hydrazides: Potent Antioxidants. Khan, K. M.;, Rani, M.; Ambreen, N.; Ejaz, A.; Perveen, S.; Haider, S. M.; Choudhary, M. I.; Voelter, W. Lett. Drug Desig. Discov., February 2012, 9, 135-139. 11/14 Dr. Nida Ambreen 19. Bis Schiff Bases of Isatin: A new Class of Antioxidant. Khan, K. M.; Khan, M.; Ambreen, N.; et al., J. Pharm. Res., 2011, 4, 3402-3404 20. 3D-QSPR Method of Computational Technique Applied on the Red Reactive Dyes by Using CoMFA Strategy. Uzma Mahmood, Sitara Rashid, S. Ishrat Ali, Rasheeda Parveen,Zaheer -ul-haq, Nida Ambreen, Khalid Mohammed Khan *, Shahnaz Perveen,Wolfgang Voelter. Int. J. Mol. Sci., 2011, 12, doi:10.3390/ijmsl20x000x. 8862-8877 21. Sana, A.; Khan, S. W.; Zaidi, H. J.; Ambreen, N.; Khan, K. M.; Perveen, S. Synthesis and Antimicrobial Activities of Amide Derivatives of 4-[(2-Isopropyl5-methylcyclohexyl)oxo]-4-oxobutanoic acid. Natural Science, 2011, 3, 855-861 22. Hussain, Z.; Khan, K. M.; Perveen, S.; Ambreen, N.; Rehman. W.; Ullah. A. The Effect of Cadmium and Chromium Concentration, on Biological Activity of Marsilea minuta. J. Chem. Soc. Pak., 2011, 33, 874-875 23. Khan, K. M.; Ambreen, N.; Halim, S. A.; Zaheer-ul-Haq, Wadood, A.; Chaudhary, M. I.; Atta-ur-Rahman. Structure-Based Design, Synthesis and Biological Evaluation of Selective β-Glucuronidase Inhibitors. J. Med. Chem., 2012, (under review) 24. Khan, K. M.; Ambreen, N.; Mughal, U. R.; Jalil, S.; Perveen, S.; Choudhary, M. I. 3-Formylchromones: Potential Antiinflammatory Agents. European Journal of Medicinal Chemistry, 2010, 45, 4058. 25. Khan, K. M.; Mughal, U. R.; Ambreen, N.; Rama, N. H.; Perveen S.; Choudhary, M. I., Schiff Bases of Isatin: Inhibitory Potential towards Acetylcholinesterase and butyrylcholinesterase. Letters in Drug Design & Discovery 2010, Vol. # 7, Issue 10. 26. Khan, K. M.; Mughal, U. R.; Ambreen, N.; Khan, A.; Perveen S.; Choudhary, M. I., Synthesis and Leishmanicidal Activity of 2,3,4-Substituted-5-Imidazolones, Journal of Enzyme Inhibition and Medicinal Chemistry, 2010, 25, 27. 27. Khan, K. M.; Ahmed, S.; Ambreen, N.; Hussain, S.; Perveen, S.; Choudhary, M. I., 3-Substituted Isocoumarins as Thymidine Phosphorylase Inhibitors. Letters in Drug Design and Discovery, 2010, 7, 265. 12/14 Dr. Nida Ambreen 28. Khan, K. M.; Ambreen, N.; Hussain, S.; Perveen, S.; Choudhary, M. I., Schiff Bases of 3-Formylchromone as Thymidine Phosphorylase Inhibitors, Bioorganic Medicinal Chemistry, 2009, 17, 2983. 29. Khan, K. M.; Ahmad, A.; Ambreen, N.; Afroz, A.; Perveen, S.; Khan, S. A.; Choudhary, M. I., Schiff Bases of 3-Formylchromones as Phytotoxic, Antibacterial, and Antifungal Agents, Letters in Drug Design And Discovery, 2009, 6, 363. 30. Khan, K. M.; Mughal, U. R.; Ambreen, N.; Khan, A.; Perveen, S.; Choudhary, M. I., Schiff Bases of Istain: Antiglycation Activity, Letters in Drug Design And Discovery, 2009, 6, 358. 31. Khan, K. M.; Fatima, N.; Ambreen, N.; Rasheed, M.; Jalil, S.; Perveen S.; Choudhary, M. I. 1,3,4-Oxadiazole-2(3H)-thione and Its Analogous: A New Class of Non-competative Nucleotide Pyrophosphatases/phosphodiesterases 1 Inhibitors. Bioorganic Medicinal Chemistry, 2009, 17, 7816 32. Khan, K. M.; Khan, A. R.; Ambreen, N.; Perveen, S.; Voelter, W., High Performance Liquid Chromatographic Quantitative Determination of Amcinonide and Benzyl Alcohol in Pharmaceutical Preparations, The Open Analytical Chemistry Journal, 2008, 2, 74. 33. Zaidi, J. H.; Arfan, M.; Khan, K. M.; Ambreen, N.; Perveen, S., Reactions of NProtected L-Amino Acids with AlkylChloromethyl Ethers and Chloromethylmethyl Sulfide, Letters in Organic Chemistry, 2006, 3, 242. 34. Zaidi, J. H.; Naeem, F.; Ambreen, N.; Khan, K. M.; Pang, Y-P.; Cusack, B.; Richelson, E.; Anwar, A.; Voelter, W., Pyrrole-Based Partial Peptidic Mimic of Neurotensin (8-13): Design and Synthesis, Letters in Organic Chemistry, 2005, 3, 21. 35. Khan,K. M.; Saify, Z. S.; Khan, M. T. H..; Butt, N.;, Maharvi, G. M.; Ambreen, N.; Perveen, Shahnaz.; Choudhary, M. I.; Atta-ur-Rahman.; Supuran., C. T.; Tyrosinase inhibition: conformational analysis based studies on molecular dynamics calculations of bipiperidine based inhibitors, Journal of Enzyme Inhibition and Medicinal Chemistry, 2005, 20, 401. 13/14 Dr. Nida Ambreen PUBLICATIONS IN ACCEPTED/SUBMITTED/PROGRESS 1. Khan, K. M.; Taha, M.; Ambreen, N.; Disulfide A Novel Class of Urease Inhibitors. Eur. J. Med. Chem., (Submitted) 2. Phosphoric Acid Manufacturing Through Hydrochloric Acid Route by Solvent Extraction. Muhammad Ashraf Khan, Muhammad Arif, Imtiaz-Ud-Din , Khalid Mohammed Khan, and Nida Ambreen. 3. The Disposal of Waste Low Density Polyethylene by Co-Liquefaction with Coal by Microwave-Metal Interaction Pyrolysis in a Copper Coil Reactor. Zahid Hussain, Khadim Hussain, Khalid Mohammed Khan, Shahnaz Perveen and Nida Ambreen. 4. An Expeditious Solvent-Free Approach towards the Synthesis of Smaller Ring Sized Aromatic Exocyclic Amine’s Schiff Bases. khalid Mohammed Khan, Tariq Khan, Nida Ambreen, Sammer Yousuf and Guillermo Antonio Morales. 5. Khan, K. M.; Ambreen, N.; Kareem, A.; Khan, A.; Sumiya.; Choudhary, M. I. Synthesis and Urease Enzyme Inhibitory Effects of Thiazole derivatives, Bioorganic Medicinal Chemistry, (Submitted). 6. Preparation of Bioorganic Rechargeable Betteryusing Urea and Chickpea Protein for the Storage and Generation of Electrical Power. Zahid hussain, Aman Ullah, Akram Shah, Nida Ambreen, et al., J. Chem. Soc. Pak., (Submitted) 7. Khan, K. M.; Ambreen, N.; Kareem, A.; Khan, A.; Sumiya.; Choudhary, M. I. Thiazoles: New Class of β-Glucuronidase Inhibitors; Bioorganic Medicinal Chemistry, (Submitted). 8. Khan, K. M.; Ambreen, N.; Ahmed, S.; Perveen, S.; Choudhary, M. I., Antibacterial, and Antifugal Activities of 3-Substituted Isocoumarins. Letters in Drug Design and Discovery, (Submitted) 9. Khan, K. M.; Ambreen, N.; Ahmed, S.; Perveen, S.; Choudhary, M. I., Antioxidant activities of 3-Substituted Isocoumarins. Letters in Drug Design and Discovery, (In Progress) 10. A convenient and selective method for the synthesis of disulfides. Khan, K. M.; Taha, M.; Ambreen, N.; Open Org. Chem J., (Submitted) 14/14