PMA version 2.3 software description No part of presented information can not be copied or distributed without permission of the Pulse Academy ©. Queries are sent to: Tiger-Telecom Co. Ltd., 58 Partizansky Ave., Vladivostok, 690002, Russia, mailto: tiger-telecom@mail.ru See also: 1. Sensor Installation 2. Software Installation 3. Sensor and software settings 4. Sensor’s resource 5. Routings of software usage 6. Pulse registration 7. The article “Secret Order of the Chinese Five elements” Launch After software installation the following shortcuts appear: On desktop PMA v2.3 and under Start menu in Pulse Analytical System folder: Uninstall PMA v2.3 PMA website To launch software click on the PMA v2.3 shortcut When software starts the Main window will appear. Screens: Main window Archive Pulse recording Sensor control panel 1. Sensor 2. Signal 3. Pulse 4. Log 1 Analysis 1. Qi 2. Tridosha 3. Acid-Base Balance 4. Qi Matrix 5. Print Recipe – correlation analysis Statistics – the history of changes in organism Help Main screen The window is divided on to several parts: Work area - where all other windows appears (analysis, record pulse, and print preview). Status panel - shows current state of a sensors: 2 o Button with sensor name indication allows to open sensor control panel. Left menu - provides quick access to program functions: o Archive - opens Patient list (if it is open the button is grayed). o Record pulse – It has several functions: Opens pulse registration window, works only if archive window is opened and patient selected. In pulse registration window - makes paused/stopped registration. o Recipe – correlation analysis function to find proper remedy for current state of a patient or compare the state with the bases of known cases. o Statistics – allows compare different pulse records to find consistent pathology or watch efficiency of treatment strategy. o Help [F1] - opens help system. o Exit – shutdowns the task. Top menu - contains additional controls: o Main / Sensor - Opens Sensor control panel. o Main / Auto-registration – switch between manual and automatic registration methods. o Main / Women pulse positions correction – developers suggest that traditional Chinese positions for women have mistakes. The experimental correct theoretical positions are switched On by checkmark “On”. o Main / Pulse automatic gain control - enables/disables automatic gain control of signal in pulse registration. o Language - selects interface language. o Windows - holds list of current opened windows. o About - opens about panel. Archive Archive - keeps patients data. Left part of window holds the patient list. Right part contains tabs which are displaying information on selected patient. 3 List of Patients: Add button - adds new patient card. Minus button - deletes selected patient card. Find - enter patient last name to find it. Sorting menu - sorts list by selected parameter. When you click the right button of your mouse at proper patient, the functions are accessible as follow: Select Archive folder – you may find another archive on computer or in the net. Import user data from file – your friend may send pulse data via e-mail and you can analyze it at your own computer. 4 Copy user data to buffer – you can export any pulse data into file and send it to your friend for analysis. Copy PAS v3 database – data from your old PMA(PAS) databases can be imported into present archive. Patient Card This tab contains contact info on patient: Name, Gender (Gender is strictly compulsory for correct pulse registration), date of birth and other. Save changes - click this button to save changes immediately. Card - Pulse registrations This tab keeps records of pulse of selected patient, you may add a short note to each record (250 chars max). 5 PMA Analysis - opens analysis window for selected pulse record (double click on record). Minus - Delete pulse record - click this button to delete selected pulse record. Card - History This tab purpose is to hold the medical history, and other text information on selected patient. Maximal page size is virtually unlimited. Add page - adds blank page to history. Delete page - deletes page from history. 6 Pulse recording Pulse recording is carrying out automatically and needn't any control by default. When the pulse taking is finished, the record saves into archive and analysis window opened automatically. In the left part of window you can see signal from pulse sensor (green line). In the right part of window you can see two tabs: Pulse - current detected pulse wave (and fits pulse quality settings). Navigation - guide through points of pulse registration (in 12 positions mode). In bottom part of the window pulse registration graphs are situated, each graph holds pulse recorded for each position. Pulse registration graphs - clicking on the graph will switch current position to select. 7 If Manual Mode enabled (on Main window), the additional controls appears on pulse registration window. Auto position - click to disable automatic position switch. Start/Stop - starts / stops pulse sensor. Pause - pauses pulse record, sensor will remain on. Clear - clears all pulse recorded. Save to archive - saves pulses into the archive. Analysis - opens analysis of current recorded pulses. Sensor control panel Sensor control panel is placed at the bottom of the software window and it manages settings of sensor and software. At upper side of the panel is information about linked up sensor: Com Port (COM1-COM254). ID – serial number of the sensor. Registrations left – the quantity of possible complete pulse analysis procedures (see. Sensor resource). 1. Sensor This bookmark manages the discretization frequency of pulse signal. Press Parameters section and set the required figures at window Set (proper meaning is in the passport to your sensor supplied together with CD). 8 2. Signal This bookmark manages signal filters. More detailed information is at Sensor and software settings 3. Pulse This bookmark manages pulse quality and pulse taking method. If you are in process of training or patient has unstable Pulse, you may decrease quality parameters. Pulse registration mode at present is Ce-May. The Trigram method is under research process. Pulse split settings and Split mode are research parameters and they are not changed. 4. Log It indicates system messages during the sensor operation. 9 Analysis PMA Analysis window represent analyzed date at sections as follow: 1. 2. 3. 4. 5. 6. Qi section TriDosha section Qi section Acid-Base Balance section Qi Matrix section Print section 1. Section “Qi” This section is represented by diagrams as follows: «Qi circulation», «Yang- Yin Qi», «Absolute meanings of Qi». This section represents parameters of pulse analysis at the lowest level of the Qi hierarchy. To start further investigation of pulse data, please explore the hypothesis of developers regarding some details of correlation with Chinese philosophy, the Five Elements and the physical phenomena. Read the hypothesis. For western mind practitioner we transformed the Six Phases structure of Traditional Chinese Medicine in relation to cells metabolism. For more information regarding association of Six Phases and cell’s metabolism please read article at the site of Pulse Academy: http://pulse-academy.org/files/ActionPotentialEN.pdf Here is the table of correlation: 10 Type of Element (kind of Qi) Metabolic function The Wind Qi is associated with Ca++ ion. Function of Calcium Wood (Wind) • • • • • • • • • • cycle. • • Circulatory - excites the heart, constricts small blood vessels Excretory - inhibits water loss Digestive - in excess, is constipating Nervous - slows nerve impulse transmission Reproductive - required for normal cell division Endocrine - inhibits release of thyroid-releasing and other pituitary hormones Blood - stimulates blood formation and is required for blood clotting Muscular - reduces muscular irritability and contractibility Skeletal - main component of bone Metabolic - required for phosphorus metabolism and energy production in the Krebs Detoxification - inhibits uptake of lead, antagonizes cadmium. Cellular - decreases permeability of cells to sodium and potassium ions. When it prevails inside cells the symptoms of Ca++ deficiency is arise due to high catabolic activity of cells: fast oxidation, muscle cramps and spasms, irritability, nervousness, anxiety, fight-flight reaction, insomnia, high blood pressure; When it prevails outside cells the symptoms of Ca++ excess arises due to high anabolic activity: slow oxidation, fatigue, apathy, depression-mental, withdrawal-social, kidney stones, gall stones, arthritis, hardening of arteries, constipation. When there is general deficiency of Ca++, the following symptoms have a place: bruising, tooth decay, osteoporosis, increased tendency to absorb lead and cadmium. The Heat Qi is associated with K+ ion. Function of Potassium Fire (Heat) • • • • • Circulatory - lowers heart rate, dilates arteries, can reduce blood pressure Excretory - maintains acid-base balance Digestive - increases digestive tract activity Endocrine - helps raise aldosterone and other hormones Metabolic - involved in carbohydrate metabolism When K+ prevails inside cells there is anabolic state of cell and following symptoms of deficiency are possible: low blood sugar, low blood pressure, slow oxidation; When K+ prevails outside cells the symptoms of excess are possible due to catabolic activity of cell: high blood sugar (diabetes), fast oxidation, weakness-muscles, depressionmental, muscle spasms. When there is general deficiency of K+, the following symptoms are possible: fatigue, skin problems, water retention, irregular heart beat, constipation, allergies, and muscle 11 weakness. The Dampness Qi is associated with OH- ion. Function of Hydroxide ion. Earth (Dampness) • Hydroxyl radicals can occasionally be produced as a byproduct of immune action. Macrophages and microglia most frequently generate this compound when exposed to very specific pathogens, such as certain bacteria. The destructive action of hydroxyl radicals has been implicated in several neurological autoimmune diseases such has HAND when immune cells become over-activated and toxic to neighboring healthy cells. • The hydroxyl radical can damage virtually all types of macromolecules: carbohydrates, nucleic acids (mutations), lipids (lipid peroxidation), and amino acids. The hydroxyl radical has a very short in vivo half-life of approximately 10−9 seconds and a high reactivity. This makes it a very dangerous compound to the organism. Unlike superoxide, which can be detoxified by superoxide dismutase, the hydroxyl radical cannot be eliminated by an enzymatic reaction. Mechanisms for scavenging peroxyl radicals for the protection of cellular structures includes- Endogenous antioxidants such as melatonin and glutathione, and Dietary antioxidants such as mannitol and vitamin E. When OH- ion prevails inside cells there is catabolic state of cell and following symptoms of deficiency are possible: fast oxidation, muscle cramps and spasms, irritability, nervousness, anxiety, fight-flight reaction, insomnia, bruising; When OH- prevails outside cells the symptoms of excess are possible due to anabolic activity of cell: difficulties to breathe, nausea, numbness, prolonged muscle spasms, muscle twitching, hand tremor. If it isn’t treated right away, severe symptoms can develop. These symptoms could lead to shock or coma. Severe symptoms include: dizziness, difficulty breathing, confusion, stupor, coma. The Dryness Qi is associated with Mg++- ion. Functions of Magnesium Metal (Dryness) • Excretory - prevention of kidney stones • Digestive - laxative • Nervous - maintains nerve conduction • Muscular - prevents tissue calcification, needed for muscle contraction • Skeletal - required for bone formation • Metabolic - required for energy production, for glucose and fat metabolism, and for protein synthesis • Detoxification - required for liver activity When it prevails inside cells the symptoms of Mg++ excess are arises due to high anabolic activity of cells: slow oxidation rate, fatigue, lethargy, confusion, diarrhea, low blood pressure, muscle weakness, depression, mental confusion; When it prevails outside cells the following symptoms of Mg++ excess are arises due to high catabolic activity: it often indicated that magnesium is being lost through the hair, 12 resulting in deficiency symptoms such as anxiety and hyper-irritability; When there is general deficiency of Mg++, the following symptoms have a place: fast oxidation rate, anxiety, irritability and high-strung personality. The Cold Qi is associated with Na+- ion. Functions of Sodium • • • • • Water (Cold) Circulatory - maintenance of blood pressure, increases heart rate Excretory - helps maintain acid-base balance Digestive - required to produce hydrochloric acid in stomach Endocrine - reduces aldosterone secretion Detoxification - keeps toxic substances in solution Sodium Deficiency Symptoms: fatigue, weakness, low blood pressure, slow oxidation rate, low hydrochloric acid level, anorexia, depression-mental, apathy, poor protein digestion, bloating-abdominal, allergies, dizziness Sodium Excess Symptoms High blood pressure, water retention, headache, fast oxidation rate, nervousness, lowers calcium and magnesium level, irritability. When the Na+ ion is out of cells, it stimulate anabolic reactions. When Na+ ions enter the cell, the catabolic phase begins. The Warm Qi is associated with H+- ion. Functions of Hydrogen Hydrogen ions help to maintain the pH body by: CO2 + H20 <==> H2CO3 (reversible). This is one of the critical function of hydrogen ions because pH has a widespread effect in our body. Alter of pH may affected respiratory control (PCO2 levels, mainly OH-) and cardiac function, digestion system, renal control, and enzyme activity. Enzyme denature in too acidic environment consequently affected metabolism pathway that involved enzymes, such as glycolysis, storage of glycogen and fatty acid etc. The disturbances in pH may also results in derangements in blood clotting and drug metabolism. Fire-Minister (Warm) Signs of H+ ions excess (acidosis) There are several types of acidosis: - Respiratory Acidosis - fatigue or drowsiness, becoming tired easily, confusion, shortness of breath, sleepiness, headache; - Metabolic Acidosis - rapid and shallow breathing, confusion, fatigue, headache, sleepiness, lack of appetite, jaundice, increased heart rate, breath that smells fruity (a sign of diabetic acidosis (ketoacidosis)). Without prompt treatment, acidosis may lead to the following health complications: - Kidney stones, chronic kidney problems, kidney failure, bone disease, delayed growth. 13 Signs of H+ ions deficiency (alkalosis) are the same like excess of Dampness Qi Six Phases structure is common for any process in organism. For example here is the scheme of Mitosis: The process of mitosis is divided into 6 stages. The Interphase, Prophase, Metaphase, Anaphase, Telophase, and Cytokinesis. At Interphase, there is only one cell, but after Cytokinesis there are two identical cells. Before mitosis can take place, the cell need to store enough energy to drive the chemical processes during the cell division. During this period of time, there is intense cellular activity. The cell grows in size. The length of the grow phase varies between a few hours to a few months. When the cell has stored enough energy, it is ready to divide itself. The following pictures shows a series of steps of how chromosomes divide. Note that for simplicity, only a few chromosomes are drawn. Sequence of Stages 1. 2. 3. 4. 5. 6. Interphase (Wood) Prophase (Fire) Metaphase (Earth) Anaphase (Metal) Telophase (Water) Cytokinesis (Fire-Minister) 1. Interphase (Wood) DNA has replicated, but has not formed the condensed structure of chromosome. They remain as loosely coiled chromatin. The nuclear membrane is still intact to protect the DNA molecules from undergoing mutation. 2. Prophase (Fire) The DNA molecules progressively shorten and condense by coiling, to form chromosomes. The nuclear membrane and nucleolus are no longer visible. The spindle apparatus has migrate to opposite poles of the cell.. 14 3. Metaphase (Earth) The spindle fibres attach themselves to the centromeres of the chromosomes and align the chromosomes at the equatorial plate. 4. Anaphase (Metal) The spindle fibres shorten and the centromere splits, separated sister chromatids are pulled along behind the centromeres. 5. Telophase (Water) The chromosomes reach the poles of their respective spindles. Nuclear envelope reform before the chromosomes uncoil. The spindle fibres disintegrate. 6. Cytokinesis (Fire-Minister) This is the last stage of mitosis. It is the process of splitting the daughter cells apart. A furrow forms and the cell is pinched in two. Each daughter cell contains the same number and same quality of chromosomes. Six-phase pattern is not limited only by mitosis. Any process in the body has the same structure. For example - the process of inflammation Russian phytotherapeutist Karp Treskunov (http://www.treskunov.ru/english_texts.html) had described as follows: - Hyperemia (Wood) - Edema (Fire) - Infiltration (Earth) - Necrosis (Metal) - Lysis (Water) 15 - The last stage of inflammation - the result of the transition to the normal state (Fire-Minister). The entire space of the body is divided into 12 different types of areas. Each individual region of cells has own simultaneous sequence of six-phase processes. Activity of cells is determined by the order in a daily circulation of Qi as it is defines for acupuncture meridians in Traditional Chinese Medicine. The interaction of cells of 12 types (meridians in Chinese medicine) forms a functional wholeness of organism. The short names of the meridians are in are given in accordance with resolution at the Geneva Conference on Acupuncture in 1989: GB - Gall Bladder, LR - Liver, ST - Stomach, SP - Spleen BL - Bladder, KI - Kidneys, SI - Small intestine, HT - Heart LI - Large intestine, LU - Lungs TE - Triple Energizer PC - Pericardium. Defining the essence of Qi is impossible without concept of "changes", "alterations" (I Ching). Therefore, the most appropriate process, describing the changes consists of certain vibrations, oscillations, which have the physical parameters like amplitude, phase and frequency. Accordingly, each fluctuation in the spectral analysis of pulse wave can be classified into six types based on the concept of a six-phase structure of any process, which in it's own turn is a result of the energy movement in three-dimensional space. In accordance with our research (http://pulse-academy.org/files/LifeMechanicsEN.pdf) there is following correlation between colours, meridians and essential metabolic ions : In the figure above there is following association: GB - Gall Bladder, green colour vibrations - yang (extracellular) disposition of OH- ion stimulates Anabolic phase; LR - Liver, red colour vibrations - yin (intracellular) disposition of Ca++ ion stimulates Catabolic phase; 16 LU – Lungs, turquoise colour vibrations - yin (intracellular) disposition of Mg++ ion stimulates Anabolic phase; LI - Large intestine, yellow colour vibrations - yang (extracellular) disposition of K+ ion stimulates Catabolic phase; ST - Stomach, blue colour vibrations - yang (extracellular) disposition of Na+ ion stimulates Anabolic phase; SP – Spleen, green colour vibrations- yin (intracellular) disposition of OH- ion stimulates Catabolic phase; PC - Pericardium., purple colour vibrations - yin (intracellular) disposition of H+ ion stimulates Anabolic phase; SI - Small intestine, turquoise colour vibrations - yang (extracellular) disposition of Mg++ ion stimulates Catabolic phase; BL - Bladder, red colour vibrations - yang (extracellular) disposition of Ca++ ion stimulates Anabolic phase; KI - Kidneys, blue colour vibrations - yin (intracellular) disposition of Na+ ion stimulates Catabolic phase; HT – Heart, yellow colour vibrations - yin (intracellular) disposition of K+ ion stimulates Anabolic phase; TE - Triple Energizer, purple colour vibrations - yang (extracellular) disposition of H+ ion stimulates Catabolic phase. Please note here: organs associated with meridians of Traditional Chinese Medicine during the order of daily circulation produce alternating metabolic phases. Thus, paired meridians with the similar colour stipulate the sector of activity of proper vibrations (or metabolic ion) at proper period of a day. There are following pairs: GB and SP form the sector from 23.00 to 11.00 with a maximum of green colour activity at 05.00 (synthesis from vibrations of LU (turquoise) and LI (yellow) meridians); ST and KI form the sector from 07.00 to 19.00 with a maximum of blue colour activity at 13.00 (synthesis vibrations of PC (purple) and SI (turquoise) meridians); BL and LR form the sector from 15.00 to 03.00 with a maximum of red colour activity at 21.00 (synthesis vibrations of HT (yellow) and TE (purple) meridians); LU and SI form the sector from 03.00 to 15.00 with a maximum of turquoise colour activity at 09.00 (synthesis vibrations of ST (blue) and SP (green) meridians); PC and TE form the sector from 11.00 to 23.00 with a maximum of purple colour activity at 17.00 (synthesis vibrations of BL (red) and KI (blue) meridians); HT and LI form the sector from 19.00 to 07.00 with a maximum of yellow colour at 01.00 (synthesis vibrations of GB (green) and LR (red) meridians); As you can see: Green colour activity at 05.00 is opposite to purple colour activity at 17.00 – pair of H+ and OH- ions. This period in Ayurveda reflects the activity of Vata dosha; Blue colour activity at 13.00 is opposite is opposite to yellow colour activity at 01.00 – pair of Na+ and K+ ions. This period in Ayurveda is associated with Pitta dosha; Turquoise colour activity at 09.00 is opposite to red colour activity at 21.00 – pair of Mg++ and Ca++ ions. This period is Ayurveda is associated with Kapha dosha. 17 Thus, these 3 pairs of ions: OH- and H+ (Vata dosha); Na+ and K+ (Pitta dosha); Ca++ and Mg++ (Kapha dosha) And they are also in the base of acupuncture rule “Day-Midnight” of Traditional Chinese Medicine for energies of opposite meridians in daily circulation. Here are indeed: GB (OH-) is opposite to PC (H+); LR (Ca++) is opposite to SI (Mg++); LU (Mg++) is opposite to BL (Ca++); LI (K+) is opposite to KI (Na+); ST (Na+) is opposite to HT (K+); SP (OH-) is opposite to TE (H+). It is also easy to notice that the main metabolic ions in Western medicine are essential minerals which works as a basic method to manage the condition of the organism in critical situations and during resuscitation procedures. Also, the pair of ions produce the following function: H + and OH- form acid-base balance, and all the electrical potentials of the whole body; K + and Na + ensure the functioning of organs and systems associated with the sympathetic nervous system; Mg ++ and Ca ++ ensure the functioning of organs and systems associated with the parasympathetic nervous system. From the metabolic point of view the opposite meridians at any moment of daily circulation must have opposite metabolic condition. For example: When GB is at Anabolic phase, the PC must be in Catabolic one and vice versa. This statement is true for all opposite meridians in daily circulation. Disposition of ions during metabolic phases: From point of view of metabolic phase, six above mentioned ions are divided into 2 groups: 18 o o conditionally alkaline: OH-, Na+, Ca++; conditionally acid: H+, K+, Mg++ During the metabolic phases they have following disposition: The given disposition of ions creates metabolic potentials. If proper concentration of ions in dynamic is violated, only in this case the disease is possible. If dynamic concentration is normal – no disease is possible. Now, let’s learn the readings of Pulse Metabolic Analysis software. Here is the main screen of readings: 19 There are several level of usage this data. a. Fast evaluation (it is suited for the 95% cases); b. Detailed evaluation for the hard, complicated cases. Fast evaluation For the “Fast evaluation” we use only one diagram: “Yang-Yin Qi” (see it on the right side of the main screen of PMA software (after “PMA Analysis” button is pressed)). To learn fast evaluation approach we use statements from our article: work "Metabolic sense of the six Qi of the Chinese Medicine»: http://pulse-academy.org/files/ActionPotentialEN.pdf, All 12 functional systems (meridians) of the body are divided into 4 groups on the base of synchronous similarity of metabolic phases (at represented groups below anabolic and catabolic phases go simultaneously): a) Yang Group of odd system of meridians: GB, ST, BL; b) Yin Group of odd system of meridians: LU, PC, HT; Please note, if we combine Yin and Yang systems in to the sole scheme, we’ll get the colour hierarchy of the solar spectrum: Red (BL) – Yellow (HT) – Green (GB) – Turquoise (LU) – Blue (ST) – Purple (PC – the beginning and end of the cycle) 20 Graphically metabolic activity of odd systems is as follow: At diagram above, if we see for example LU meridians, it means at the same metabolic state are at PC and HT meridians too. Please remember: LU, PC, HT and ST, BL and GB meridians works together, but Yin and Yang meridians are in opposite metabolic phases. c) Yang group of even systems of meridians: TE, LI, BL: d) Yin group of even systems of meridians: LR, SP, KI: 21 Graphically metabolic activity of even systems is as follow: Positive inclinations in graphs show the periods of catabolic activity of systems (meridians), and negative inclinations indicate the anabolic phase. There also 2 groups (Yin and Yang) that have similar metabolic phase at any time of daily circulation: When LR, SP, KI are in catabolic phase, LI, SI, TE are in anabolic phase and vice-versa. Ideally balanced person has any of 4 groups of systems (meridians) working at each metabolic phase at periods of 4 hours forming the full metabolic cycle at duration for 8 hours ( 4 hours of anabolism + 4 hours of catabolism). Thus, there are 3 metabolic cycles a day for each group of meridians. But the cycle of daily period astronomically is divided into alkaline and acid part and our bodies are adapted to these changes: At conditionally DAY period (from 11.00 to 23.00, when it is time of activity of Water, FireMinister and Wood elements), the person has usually moderate physical activity, the arterial blood is shifted to alkaline side due to respiratory effect. This alkaline shift stipulates the following profile of “Yang-Yin Qi” diagram at ideal case: 22 At conditionally Night period (from 23.00 to 11.00, when it is time of activity of Fire, Earth and Metal elements), the person has usually rest period, the arterial blood is shifted to acid side due to respiratory effect. This acid shift stipulates the following profile of “Yang-Yin Qi” diagram at ideal case: Special Notes: At Day-Night profiles evaluation of “Yang-Yin Qi” diagrams the very first focus should be given to the conditions of Arterial and Venous blood. The acid=base balance of blood is the post essential factor that stipulates the metabolic processes of ALL cells in the body. a) Meridian TE (Triple Energizer), up to our view, indicates the acidic or alkaline shift (relatively to the middle value of homeostatic regulations) of arterial blood, which plays a role in creating a charge of membrane potential for cells of LU, LI, PC, SI, HT, TE and cells of blood in arterial vessels. Positive values (shift to the acid side) stimulate catabolic state of LU, LI, PC, SI, HT and cells in arterial vessels. Negative values of TE stimulate the anabolic activity of the mentioned systems. b) Meridian PC (Pericardium), up to our view, indicates the acidic or alkaline shift of venous blood - GB, LR, ST, SP, BL, KI association. Positive inclination at the diagram means a shift to the acid (catabolic) side of GB, LR, ST, SP, BL, KI and cells in venous vessels, but negative one shows a shift to the alkaline (anabolic) side. c) At normal, balanced condition TE and PC systems must have opposite direction of inclinations, i.e. in this case one of the systems is in alkaline condition, but another – at acid or vice-versa. Only this mutual disposition creates proper electro-magnetic potential to move the blood in vessels. Total shift with the similar levels and direction of inclination (including both near zero line) to be considered as pathological and this condition must be corrected at the FIRST TURN because acid-base balance of blood is associated with level of toxin in the whole body. At any 23 condition use methods of detoxification, especially correct the drinking quantity of PURE WATER (we consists of water up to 75% and low circulation of liquids increases level of toxins in our bodies dramatically). Toxins in the body are the main cause of metabolic disorder and NO disease is possible if metabolic order is perfect. d) The second point of your attention must be paid to the synchronous of the daytime to the type of profile. Generally Night profile indicates some level of hypoxia, when the whole body should have a rest and requirements of Oxygen are low. If we see the Night profile at daytime, please be sure, we have some stage of hypoxia in dependence on the value of Qi inclination. The hypoxia is a cause of a very long list of disease and the most know of them are ischemia, cancer, toxemia. Detailed evaluation Detailed evaluation of the pulse data is available with help of “Qi circulation” diagram. Please note, the readings of this diagram will be valid only if you have taken pulse at proper pulse positions (see the section “Pulse registration” of present manual). As it was mentioned before, “Qi circulation diagram” is used at rare complicated cases and this approach requires much more time fro analysis then the method of fast evaluation. Normally, at balanced health condition the "Qi circulation" diagram shows different reading at different procedures of measurements: Very Important note: o In the "Yellow Emperor's Inner Canon: " there is the following sentence: "Therefore it comes out of the same, but the names are different. If you have wisdom - get down to the same (look for something that explains), but you are stupid, if looking for differences. ... ". o That is why a competent doctor will look only for similarities in changeable measurements of pulse reading - exactly persistence of definite inclination from one measurement to another one is the pathological source of disease. Permanent pattern of inclination disrupts the harmony of coexistence of the body with harmony of the Nature because the Nature is changeable at any a tiny moment. The standard Western logical approach usually unwittingly is focusing on data that contradict each other and fluctuating data causes the mind confusion. You should neutralize this inner impulse to analyze differences between readings but it is required to concentrate only at duplicating data (signs of Qi flow abnormalities). o To select the most persistent inclinations of Qi, please use the function “Statistic” in accordance with description below in this text. Now let’s study the “Qi circulation” diagram: 24 Here are: Red line – Wind Qi – Ca++ ion; Black Yellow line – Heat Q – K+ ion; Green line – Dampness Qi – OH- ion; Turquoise line – Dryness Qi – Mg++ ion; Blue line – Cold Qi – Na+ ion; Purple line – Warm – H+ ion. For the healthy and balanced person in dependence on daytime period (similar like for “Yang-Yin Qi” diagram) in the “Qi circulation” chart the structure of inclinations must be as follow: For the Day profile – all Qi at Yin meridians are positive and at Yang meridians are negative; For the Night profile the inclinations are completely inversed to the Day profile. At any case, ideally the +/- alteration of Qi inclinations must exist between Yin and Yang meridians. For example for the represented case above there is night time profile. If we would like to be absolutely at ideal, inside each meridians also there is inner structure of Qi: The main ion (Qi) that is associated with given meridian has the most high inclination at moment of it’s period of activity inside the daily cycle. Other Qi has less inclination in accordance with order of mutual birth – the rule of energy transformation in Traditional Chinese Medicine. For example here is the hierarchy of Q in meridians (Qi are shown in association with colour and ion): For HT at Daytime and for LI at Night time: For HT at Night time and for LI at Daytime: 25 For LU at Daytime and for SI at Nighttime: For LU at Nighttime and for SI at Daytime: The same principles of Hierarchy is used for other meridians. Please note this theoretical ideal Qi disposition is impossible to reach, otherwise we were immortal being. It will be excellent progress, if we will be able to managed Qi only by Day and Night profile. At given sample above of the “Qi circulation” diagram (there is Night profile here) it is worth only to elevate Qi at negative area for ST, LI and TE meridians and turn positive Qi into negative side in meridians SP, LU and PC. If the meanings of Qi are in the borders from +20% to+50% and from -20% to -50%, the balance is considered as excellent. Meaning of Qi near zero line (+/- 20%) indicate tendency to stagnation and meanings higher +50% or lower -50% are considered as potentially pathogenic. Please note high stress may be reflected in form of ideal distribution of Qi, but it will have inclination more then +/-50%. At given sample we can see stressed meridians: LR, KI and HT. In the graph, "Absolute values of distortions" there is the analysis of the general energy of Qi in meridians. Values more, than 100% mean the excess of general energies and it can cause acute diseases. Values less than 100% mean the lack of energies and it leads to stagnation and degradation of organs associated with proper meridians. 26 In our sample LR, KI and HT are in state of high energetic level, but ST, SP and LU indicate stagnation of energies. Please remember, this readings are valid only for correct pulse taking from proper positions. If positions are ignored for some reason (lack of limb, skin damage, etc), we can rely only on “Yang-Yin Qi” diagram, but at this case also be known that pulse taking only from one side of the body can loose information regarding the right-left imbalance. 2. Section “TriDosha” At this section Ayurvedic Tridosha are represented. There are two diagrams: - Diagram “Tridosha status of Meridians (Space)”. At this diagram represented Tridosha balance INSIDE meridians: Pitta – Red colour line, Kapha – Yellow colour line, Vata –Blue colour line. Green dotted line – summarized average activity of all doshas at each meridian (it is the same as Fulness reading). 27 Pitta dosha - it is indicator of power of oxidative processes at inner space of cells, level of production of ATP at mitochondrion. This is catabolic phase of metabolism, there is acidity of extracellular fluids. Kapha dosha - it is indicator of power of anabolic processes in cells - cell's structures are restoring with help of ATP. Anabolic phase in cells reduces blood acidity; Vata dosha - it is indicator of metabolic rate. The Vata dosha always increases imbalance. At an excess of Pitta dosha there is acceleration of oxidation and degradation of tissues, but at excess of Kapha dosha it is acceleration of tissue growth. The graph "Summarized Doshas for Yin and Yang meridians" shows the combined value of the doshas separately at Yin and Yang meridians, based on the diagram of Fulness (green dotted line in the chart “Tridosha status of Meridians (Space)”. From this point of view the summarized doshas are external relatively inner doshas of meridians. If deviations of internal and external doshas coincides, there is a fact of pathology - normally internal doshas should balance the external doshas (they should have different mutual disposition), i.e., the direction of doshas in meridians must be in opposition to the disposition of appropriate dosha in chart of summarized tridosha. Correspondence between tridosha and meridians: Pitta dosha - activity of Liver, Pericardium, Small Intestine, Gall Bladder meridians; Kapha dosha - activity of Spleen, Heart, Stomach, Triple Energizer meridian; Vata dosha – activity of Lung, Kidneys, Large Intestine, Urinary Bladder meridians. At given case above there is relative deficiency of Vata dosha at both diagrams “Tridosha status of Meridians (Space)” and "Summarized Doshas for Yin and Yang meridians". At The normal health condition average levels of dosha’s lines are at border from +20%to +50%. The stagnation is from -20% to +20% . Readings lower then -20% indicates deficiency of energies, Doshas at "Summarized Doshas for Yin and Yang meridians" has normal readings from +15% to +30%, stagnation is from -15% to +15%, excess is more then 15%, deficiency is lower then -15%. At normal state maximal difference be between columns of all tridosha is usually not more then 10%. Normally at diagram “Tridosha status of Meridians (Space)” lines should be “intertwined”. There are 3 specific types of diagrams are possible: a. Active phase of illness (at given case it is pneumonia): 28 Lines of tridosha are disposed almost parallelly (they are not “intertwined”) – there is high tension of metabolic processes. At this case columns at "Summarized Doshas for Yin and Yang meridians” are seen like at healthy condition and we have to understand the meanings at diagram “Tridosha status of Meridians (Space)” and not to be being misled. b. Normal energy condition: The "Summarized Doshas for Yin and Yang meridians” normal level of energy at borders from +15% to +30%. At diagram “Tridosha status of Meridians (Space)” energies are disposed mainly in border from +20%to +50% (except Vata dosha). Difference between columns of all tridosha is less then 10%. 29 c. Pathological deficiency of energy of all three doshas. Energies have negative value in general. The source of pathology is Vata dosha - it has relative excess at both diagrams: “Tridosha status of Meridians (Space)” and "Summarized Doshas for Yin and Yang meridians”: d. Metabolic chaos - mismatch of motion of energies at "Summarized Doshas for Yin and Yang meridians” have different polarity in the context of excess and deficiency of energy: 3. Section Acid-Base balance» Developers of PMA suggest, that the five above-mentioned chemical elements – H+, K+, Mg++, Ca++, Na+ plus the water (carrier of the Fire-Minister in TCM, hydroxyl ion OH-) define the metabolic environment for all the myriad of biochemical reactions in the body. Only certain proportions of elements hold the required electrostatic resting membrane potential (RMP) of cells. RMP creates proper condition for the large number of ionic pumps in living cells. Knowledge about the distribution of potentials among functional systems can help to understand the imbalances of the body as whole synchronized object. For example, the shift 30 towards the acidic condition of blood accelerates the growth of collagen, reduces the permeability of membranes, but from the other hand the shift to the alkaline side promotes the dissolution of proteins and fats, increase degradation of morphological structures of cells. First, here is the legend of diagrams of four indicators: - Blue line - the acid-base balance (ABB) within the cell. Ideally, at the active state of the cell (state of Yang) blue line should be at small negative position (about minus 10%). The more negative values reinforce the processes of degradation cell’s structures. A positive value will informs about overcompensation of recovery processes after stress or inclination to uncontrolled cell division. - Red Line - ABB outside of cells. Ideally, the red line should be at the level of plus 10%. The more high position informs about risk of inflammatory reactions of the cell. Readings more than 10% indicate functional deficiency of cells (lack of Ca++ ions), while negative values shows pathological processes with destruction of the structures of the intercellular space. - Purple Line – ABB of the blood. Ideally this line should be at plus 50%. It indicates a normal acid shift of blood. More positive values of purple line correspond to the more acidic blood and indicate an attempt to detoxify the body, to destroy damaging agent located in the intercellular liquid. More alkaline reaction of the blood is indicated by a more negative level of purple line – in this case process of rejuvenation is fast so far as the cancer risk also increases. - Green Line - the RMP of active cells. The ideal level of the green line is plus 10%. Excessive levels mean the risk of inflammatory reactions of cells. Deficiency of green line indicates the dysfunction of cells. The negative potential shows the development of pathological processes. At ABB diagram there are integrative indicators – Tension and Balance. Tension Tension indicator for Yin and Yang meridians shows the quantity of metabolic energy in comparing with normal level. In our case, there is a positive deviation of the intensity of 65% for the Yin meridians and 20% for the Yang meridians. Deviation at the range of 20% is norm. For positive values of tension usually shows excess of metabolic energy, stress in the body and active phase of the battle with diseases. The lack of metabolic energy associated with a predominance of anabolic reactions, and depletion of body functions. We always should lead the condition to the zero tension when we make a correction. 31 Balance Balance figure is a general indicator of deviation from the norm of Qi. Normal value of Balance is 75%. Higher value may indicate deficiency of energy. The lower value lower then 75% means the process of disease development. The lower reading shows more hard disease in dependence on how far reading from 75%. 4. Section “Qi Matrix” The Matrix represents Qi deviation in the table form. Excess of Qi is indicated by positive figures and red colour. The deficiency of Qi is shown by negative values and blue colour Qi Warm (Fire-Minister element) has positive value (acid blood reaction) in case when sum of intercellular and intracellular medium has alkaline reaction - the intercellular and intracellular liquid has excess of alkaline agents and these destroy cell’s structures. At alkaline blood reaction the condition promotes for building of cells – tissues grow fast. From this point of view the obesity metabolism and atherosclerosis may be explained – the more high blood alkalinity provides fast cells grow and at the same time the circulatory system is damaging by alkaline agents and free radicals. The body tries to repair blood vessels by cholesterol. That is why natural way to decrease obesity and decrease level of blood cholesterol is acidification of blood (all antioxidants do it). But there is the second part of the problem with antioxidants – their excessive consumption decreases rate of cells renovation and it is also the way to the aging. This contradiction is old as the life itself – everything should be balanced! The great problem with cancer disease is also associated with blood pH balance. As you can understand now – the blood alkalinity increases the cancer possibility. Probably you know, many 32 treatment protocols of cancer disease include consumption of some quantity of vinegar, especially useful is apple vinegar with high concentration of potassium (in above written text we mentioned the potassium is intracellular alkaline agent and excessive concentration of this mineral increases cell’s destruction). Doctor Jarvis was used this folk medicine receipt to cure many hard patients with help of Apple Cider Vinegar. On the example of our table a patient with diabetes can be seen that the growth of cell structures prevails in all meridians except the Liver (LR). Liver is forced to gradual degradation to compensate for the excess growth of cell structures in other meridians. 5. Print All analysis data can be printed or exported into graphical file. Recipe – correlation analysis Correlation analysis compares the specified data with digital pulse analysis profile to determine possible therapeutic effects of each element of given list of remedy. It allow select the most effective way of health correction, identify contraindications, studiey of changes in metabolism after treatment procedures. It consists of three sections: - Archive; - Resources; - Correlation. Archive was designed to select the desired patient (1), and select the desired recording pulse data (2): 33 Components – section, where the PMA user can select the desired file of components (1). The components data will be compared with patient data. Each entry in the file of components (2) has a specific profile of influence at the metabolism. This profile is shown in the matrix (3) or tape form (4). This section also allows you to see the description of components: Correlation – section, where the PMA user can run the calculation of correlation analysis (1) and get a list of sorted elements of components (2) in order to reduce contradictions with the patient health condition. At the end of the list there will be components with the most high objections to the analyzed pulse data. The value of compliance is calculated for each component (3) and it is indicated by “Correlation with diagnosis %”. The list of components may be limited with help "Gray lines limit" parameter (4). This limit is also implemented to the printed list of components (5). If the "Gray lines limit" is zero, then all components will be printed as a sorted list. 34 Statistics – the history of changes in organism This module allows track the metabolic changing in organism during some period, evaluate the effectiveness of treatment or detect the core of pathology. Press the button “Statistics” and select proper patient and his (her) readings: a b c d e f Button “Statistics”; Patient we would like to analyze; Pulse readings of the patient; Move all pulse readings to the right field for analysis. You may analyze as many pulse data as you wish, but please note at high quantity of readings it will be difficult to distinct details. 5-6 reading are sufficient to make definite conclusion; Move selected single pulse reading to the right field for analysis. Button “Clear” is used to clear the right field for analysis from the previous analysis Making analysis 35 a. Moved pulse readings for the analysis; b. Button to start Statistics calculation; c. Button to display results of Statistics analysis. Nota Bene: Qi in charts below are associated with systems in following order: for Yang meridians: Wind – Urinary Bladder, Heat – Large intestine, Dampness – Gall Bladder, Dryness – Small Intestine. Cold – Stomach; For Yin meridians: Wind – Liver, Heat – Heart, Dampness – Spleen, Dryness – Lungs, Cold - Kidneys The “Analysis” section: 3.1. “Top 10” subsection of “Analysis” section. This window shows 10 Qi (there are 60 Qi totally – 12 meridians x 6 Qi) that have the most high arithmetic sum of inclination for given quantity of readings. The inclinations number 1, 2 and 3 are essential and they are cause of energetic pathology for given patient because they indicated the most persistent pattern (stable pattern is always pathology in our permanently changeable word – it means low level of adaptation to the influence of environment). For the given patient we have diagram as follows: Here are 3 main inclinations: o Deficiency of Cold in Kidney. It means deficiency of Kidneys energy at Kidneys itself o Deficiency of Wind in Lungs. It means deficiency of Liver in Lungs; o Excess of Cold in Urinary Bladder. It means excess of Stomach energy in Urinary Bladder. 3.2. “Top 10 ABS” subsection of “Analysis” section. This diagram indicates absolute sum of inclinations in selected series of pulse readings for 10 Qi of total quantity of 60 Qi. Absolute 36 sum have meaning of general energy of interaction, associated with proper Qi. It is dangerous situation if the first 3 Qi from this diagram coincide with first 3 Qi from the chart “Top 10”. At given case we see the most highest energy level of interaction: o Heat (Large Intestine) in Gall Bladder; o Cold (Kidneys) in Kidneys; o Heat (Large Intestine) in Large Intestine. On the base of “Top 10” and “Top 10 ABS” diagrams we can see coincidence of Cold in Kidneys. It is the most pathological pattern for given patient. From the metabolic point of view it lack of Na+ ion inside the Kidneys cell, lack of catabolic activity, conditions for creation of Kidneys cysts and dysfunction, if it will remain in future. 1.3. “Top 10 S6” subsection of “Analysis” section. It is diagram to compare Qi Warm of FireMinister element. Warm Qi is energy of interaction of meridians with environment. Normally it should be at a range 20-40% both at negative of positive site. Also in dependence on metabolic condition (day or night type) the meaning of inclination should be as follows: o o Day type: Warm Qi of Yin meridians are positive, but for Yang meridians are negative; Night type: Warm Qi of Yin meridians are negative, but for Yang meridians are positive. From the other hand inclinations of Warm Qi indicate pH balance of arterial (Fire-Minister of Yang meridians) and venous (fire-Minister of Yin meridians) blood relatively homeostatic norm (positive inclination means shift to acid side, negative inclination means shift to alkaline side). Normally, if the patient is not sleeping, his condition must have Day profile of inclination, otherwise we consider the existence of hypoxia of the body. 37 For given patient we also select first 3 Qi in list. There are: - Mainly positive Stomach; - Negative Liver; - Mainly negative Heart. It is not good sign – we have night profile and Stomach, Liver and Heart metabolic condition create the most powerful negative effect in this case. Help The Help works as an Internet browser – PMA user may follow hyperlinks at words with blue colour. 38 Button Back – return you to the previous page. Refresh – sometimes Help is renewed via Internet. Close Help – close the Internet browser. <To the main page> 39