CH450 CHEMICAL WRITING AND PRESENTATION Writing Manuscripts: Title and Authors Importance of Title The title will be read by thousands of people (either in the journal contents pages or in abstracting/indexing databases), even though few people may read the whole paper. First impressions are strong impressions, hence it is advisable to choose the title with great care. Good Titles Good titles should describe adequately the paper’s contents in the fewest possible words. The terms in the title should highlight the contents of the paper. Title Styles Descriptive or Label Style. Title is a label, not a sentence, so that verbs and articles (“a” and “the”) are missing. Many journals require or prefer this style. Assertive Sentence Style. Here, the title is a sentence, with subject, verb and object. To many, such titles are overemphatic or even dogmatic and in many cases, the actual conclusions stated later in the paper are much more tentative than the title suggests. However, this style is common in some prestigious journals (e.g. Nature, Science) and in biomedical journals and is generally becoming more common. Example: W. Greenrod and M. Fenech. The principal phenolic and alcoholic components of wine protect human lymphocytes against hydrogen peroxide- and ionizing radiation-induced DNA damage in vitro. Mutagenesis, 18, 119-126 (2003). What Not to Include in Titles Articles (“a”, “the”) Verbs and words such as “Study” and “Investigation” Abbreviations (e.g. PS for Polymer-Supported or GC for Gas Chromatography) Chemical Formulas (e.g. (COOH)2 for Oxalic Acid) Proprietary (Trade) Names Jargon The above is a guide for writing label style titles (the majority). Example: D.P. De Schutter, D. Saison, F. Delvaux et al. Optimization of wort volatile analysis by headspace solid-phase microextraction in combination with gas chromatography and mass spectrometry. J. Chromatogr. A, 1179, 75-80 (2008). The above authors use a label title with no articles, verbs, abbreviations (e.g. HSSPME, GC and MS), formulas, proprietary names, nor jargon. Exceptions are to be found from time to time; some journals allow certain scientific abbreviations. 1 Example 1: C. Gouveia and E.V. Soares. Pb2+ inhibits competitively flocculation of Saccharomyces cerevisiae. J. Inst. Brew., 110, 141-145 (2004). This title is an assertive sentence title and it also contains a chemical formula. A corresponding label title might be “Inhibition of Competitive Flocculation of Saccharomyces cerevisiae by Lead (II) Ions”. Example 2: S. Bor, C. Bor-Caymaz and N.A. Tobey. Esophageal exposure to ethanol increases risk of acid damage in rabbit esophagus. Dig. Dis. Sci., 44, 290-300 (1999). Example 3: A. Barden, R.R. Zilkens, K. Croft et al. A reduction in alcohol consumption is associated with reduced plasma F2-isoprostanes and urinary 20-HETE excretion in men. Free Rad. Biol. Med., 42, 1730-1735 (2007). This title is an assertive sentence title and it also contains a chemical abbreviation, HETE. A corresponding label title might be “Reduction in plasma F2-isoprostanes and urinary hydroxyeicosatrienes in men as a result of reduced alcohol consumption”. Series Titles and Hanging Titles These title types (usually of the Descriptive or Label style) are quite common and have a general statement followed by a more specific statement. Series titles are of the type “ Mesoionic Compounds. Part IV. Synthesis and Alkaline Hydrolysis of Mesoionic 1,2,3,4-Oxatriazole-5-ones”. Some journals allow them and they were once common. However, what happens if Part IV is quickly accepted for publication, whereas there is a delay with Part III, which was submitted a few weeks earlier? Hanging titles are better. A colon (:), a full stop (.) or a hyphen (-) (depending on the journal preference) can be used to separate the two statements. Example 1: “The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity”. Science, 280, 69 (1998). Example 2: M. Assuncão, M.J. Santos-Marques, V. de Freitas et al. Red wine antioxidants protect hippocampus neurons against ethanol-induced damage: a biochemical, morphological and behavioral study. Neuroscience, 146, 1581-1592 (2007). Example 3: N.V. de Gaujelac, N. Vivas, M-F. Nonier, C. Absalon and G. Bourgeois. Study and quantification of monomeric flavan-3-ol and dimeric procyanidin quinonic forms by HPLC/ESI-MS. Application to red wine oxidation. J. Sci. Food Agric., 81, 11721179 (2001). Construction of Title: Importance of Syntax Syntax means word order, which if incorrect can convey the wrong meaning. Although the real meaning of the title is often obvious, syntax error is nonetheless serious: a title should not need translating. Many syntax errors have a comical twist to them, but even so, they do not reflect well on the authors. 2 Example: “Mechanisms of suppression of Nontransmittable Pneumonia in Mice Induced by Newcastle Disease Virus”. This title implies that the mice were induced by the virus (!). Change of syntax gives the correct meaning: “Mechanisms of suppression of Nontransmittable Pneumonia Induced in Mice by Newcastle Disease Virus”. Authors: Who is Included? The list of authors should reflect a system of credit “Few would dispute that researchers have to take responsibility for papers that have their names on them. A senior laboratory figure who puts his or her name on a paper without direct supervision or involvement is unquestionably abusing the system of credit. There have been occasions where distinguished scientists have put their names irresponsibly on a paper that has turned out to contain serious errors or fraud. Rightly, some of them have paid a heavy price. (Editorial, Nature, p. 831, 26 June 1977) What Sequence of Names? Order of authorship should be decided early in the project and certainly before the manuscript is written There are no fixed rules, but maybe the best presentation is main author (who did most or all of the work) first and the senior author marked with * (to whom correspondence should be directed). The main author is likely to be a graduate student or post-doctoral fellow, whereas the * author is more likely to be a supervisor. Include only significant contributors. This may be beyond your control, even though you performed most of the work and are writing the paper: it is not uncommon for heads of laboratories or institutes or other prestigious people to be included, even though their direct contributions are small or even nil. The average number of authors per paper is rising (Day and Gastel, p. 46). 3