CONCEPTS: DNA Structure & Replication (CH 11) & Cellular Reproduction (CH 9) The curriculum says students should know: Describe how cell reproduction contributes to repair and growth of an organism. Compare and contrast asexual and sexual reproduction. Arrange the stages of the cell cycle in sequence and summarize what happens during each stage. Describe the structure of the chromosome. Summarize the major events that occur during each phase of mitosis. Compare benign and malignant tumors and explain how cancer treatments affect cells. Summarize the experiments and conclusions that led to the discovery of DNA as the hereditary material. Identify the three components of a nucleotide. Illustrate the arrangements of nucleotides in DNA molecules. Describe the process of DNA replication. Here is how you can use your book and knowledge to prepare for those outcomes on upcoming assessments/tests: CH 11 Section 1: Describe Griffith's experiments and conclusion. o Draw a picture/cartoon explaining Griffith’s experiment. o Summarize the results of Griffith’s experiment. B. Describe Avery's experiments and conclusion. o Draw a picture/cartoon explaining Avery’s experiment. o Summarize the results of Avery’s experiment. C. Explain how experiments with viral DNA further supported Avery's conclusion. o Draw a virus: Label the protein coat & DNA A. Vocabulary: create 5-7 word definitions for the vocabulary in this section: virus, bacteriophage Summary: Write a summary statement explaining the significance of these experiments. (Why these experiments were important.) CH 11 Section 2: Identify the building blocks of DNA. o Draw a the 4 types of nucleotides Label the Deoxyribose(sugar), phosphate, & nitrogen base Circle the pyrimidines Place a square/box around the purines E. Describe DNA's structure and the rules for base pairing in DNA. o Draw a strand of DNA in the form a ladder. Labeling the parts of the nucleotides. o Draw this in the twisted shape known as a Double Helix. o Explain the concept of “complimentary base pairing.: o If the DNA strand is of the following sequence: GTCATCATTGCAAGTC Write the complimentary strand sequence. D. Vocabulary: create 5-7 word definitions for the vocabulary in this section: deoxyribosenucleic acid, nucleotide, nitrogenous base, pyrimidine, purine, double helix Summary: Write in paragraph form a description of the structure of DNA. Include as many of the following terms as possible: deoxyribosenucleic acid, nucleotide, nitrogenous base, pyrimidine, purine, double helix. CH 11 Section 3: Explain how the template mechanism is important in DNA replication. o Why is it important to have a template (original strand) to start from when building a strand of DNA? o Describe the process of DNA replication. G. What is DNA polymerase? o What is its function? H. When does DNA replication take place? F. Vocabulary: create 5-7 word definitions for the vocabulary in this section: DNA replication, DNA polymerase Summary: Write a paragraph summarizing the DNA replication process and why the template strand and complimentary base pairing are so vital to this process. CH 9 Section 1 Describe how cell reproduction contributes to repair and to growth. o Give two examples of cell reproduction helping to repair an organism. o Give two examples of cell reproduction producing growth of an organism. J. Contrast the two main ways that organisms reproduce. o Create a Venn Diagram comparing and contrasting asexual and sexual reproduction o Why does two types of cellular reproduction exist? Why wouldn’t one be enough? K. Explain how cell reproduction also contributes to the growth of a species. I. Vocabulary: create 5-7 word definitions for the vocabulary in this section: Summary: Write a paragraph summarizing the two types of cellular reproduction and WHY two types exist. CH 9 Section 2 Describe the structure of a chromosome. o Draw a picture of each of the following: Chromatin Chromosome (single) Chromosome (replicated/double) Label: sister chromatid, centromere M. Name the stages of the cell cycle and explain what happens during each stage. o Create a table that lists the stages of the cell cycle and summarizes the major events of each stage. Interphase, G1, Synthesis, G2, Mitotic, Cytokinesis o If you start the cell cycle with one cell, how many will you have at the end of the cycle? L. Vocabulary: create 5-7 word definitions for the vocabulary in this section: chromatin, chromosomes, sister chromatid, centromere, cell cycle, interphase, mitotic phase, mitosis, cytokinesis Summary: Write a paragraph summarizing the cell cycle, including how DNA changes throughout the process. CH 9 Section 3: Summarize the major events that occur during each phase of mitosis. o Create a table listing the four stages of mitosis and the major events of each stage. Include an additional column that has a drawing of what the cell looks like during that phase. o Which organelle helps produce a spindle? o What is the function of the spindle? o How are cells produced from mitosis similar and different from the parent cell? Create a Venn Diagram to show these similarities and differences. O. Explain how cytokinesis differs in plant and animal cells. o What is the purpose of cytokinesis? o Draw a picture of an animal cell compared to a plant cell undergoing cytokinesis. N. Vocabulary: create 5-7 word definitions for the vocabulary in this section: spindle, centrosome, prophase, metaphase, anaphase, telophase, cell plate. Summary: Write a paragraph that summarizes the overall events of mitosis and cytokinesis. Identify this as a type of asexual or sexual reproduction and give an example of when this type of cellular reproduction might occur. CH 9 Section 4: Compare benign and malignant tumors. o Create a Venn diagram comparing and contrasting the two types of tumors. Q. Explain how cancer treatments can work at the cellular level. o What is the purpose of the different treatments? Create a table to display this information. P. Vocabulary: Write 5-7 word definitions for the vocablulary in this section: benign tumor, malignant tumor, cancer, metastasis. Summary: Write a paragraph that explains how understanding the cell cycle allows you a better understanding of both cancer and cancer treatments.