Microbiology 1 - Introduction (Ch 1)
© copyright 2013 Marta D. de Jesus
I. Introduction [mine]
A. this class is General Microbiology
B. Nuts & bolts
1. Roll
2. Student info form
check your info on-line]
3. Syllabus
a. who am I?
b. About the class
Pre-req
c. Text
d. for lab: lab manual
e. Supplemental texts
f. Grading
g. Schedule
h. Academic dishonesty/misconduct
i. VC helps
C. Helps & hints
1. learn how to learn better
2. all of these activities take time:
3. Using the book & additional materials
a. in the chapters: the Learning Objectives are listed
b. lots of new words
1) Book bolds important terms
2) Book’s Glossary - in back
3) most of these words have have Greek or Latin pieces = word
roots in dictionaries
c. work on the Study Questions at the end of the chapters
d. online quizzes plus other resources available at:
http://highered.mcgraw-hill.com/sites/0073375292/student_view0/index.html
**Any content from an assigned Chapter or Lecture is “fair game” unless I say otherwise.
3. Other Comments/Suggestions
II. What is Microbiology?
A. characteristics of microbes
1.
2.
3.
4.
5.
6.
B. study of microbes; divided into subdivisions based on
1. research field
- taxonomic (classification)
a. bacteriology
b. protistology
protozoology
phycology / algology
d. mycology
e. virology
- process-centered
a. microbial metabolism
b. microbial genetics & molecular biology
c. environmental microbiology & microbial ecology
2. application, including
a. medical microbiology
immunology & serology
public health & epidemiology
etiology
infection control
chemotherapy
b. applied environmental
agricultural microbiology
aquatic microbiology
bioremediation
c. industrial microbiology
food & beverage (including dairy) microbiology
pharmaceutical microbiology
biotechnology, genetic engineering & recombinant DNA
III. What is Science?
A. investigating the natural world
1.
2.
3. what it isn’t
4. Why study science?
B. Scientific method
1. start with
2. make a
3. make a
4. run a
5. analyze data &
C. What is a theory?
D. controls
IV. Big Moments in the History of Microbiology
A. Diseases & problems
1. ancient diseases & microbes
2. “fermentation”
3. some famous diseases in history
a. Plague of Athens (430-410 BC)
b. Black Plague
c. great Pox
d. influenza (Spanish Flu of 1918)
e. HIV - AIDS
B. Golden Age of Microbiology (1857~1914)
(bold = from lecture; underlined in text of Chapter 1)
before:
1600s
1. Robert Hooke
2. Anton von Leeuwenhoek
3. Francesco Redi
1700s
4. Carolus Linnaeus (= Carl von Linne)
biological taxonomy
5. Louis Jablot
6. John Needham
7. Lazzaro Spallanzani
8. Edward Jenner
1800s
9. Theodor Schwann & Matthei Schleiden
10. Oliver Wendell Holmes
11. Ignaz Semmelweiss
during Golden Age
12. Florence Nightingale
13. John Snow
14. Rudolf Virchow
15. Louis Pasteur
fermentation experiment
pasteurization
16. John Tyndall
17. Ferdinand Cohn
18. Eduard Buchner
19. Joseph Lister
20. Robert Koch: Koch’s Postulates
pure culture techniques
staining
21. Walter & Angelina Hess
22. Charles Laveran
23. Elie Metchnikoff
24. Christian Gram
25. Julius R. Petri
26. Dmitri Iwanoski
27. Martinus Beijerink
28. Walter Reed
29. Paul Ehrlich
30. Emil von Behring & Shibasaburo Kitasato
31. Albert Kluyver & C. B. van Niel
32. Alexander Fleming
33. Gerhard Domagk
34. Oswald Avery/Colin MacLeod/Maclyn McCarty
35. George Beadle & Edward Tatum
electron microscopy opens new worlds
1950’s
36. James Watson & Francis Crick
37. Linus Pauling
38. Barbara McClintock
39. Carl Woese & George Fox
modern biological taxonomy
C. Modern Microbiology: very dynamic field -> “2nd Golden Age?”
infectious disease still important
some emerging & re-emerging infectious diseases (EIDs)
http://www.niaid.nih.gov/topics/emerging/pages/list.aspx
List of NIAID Emerging and Re-emerging Diseases
Group I—Pathogens Newly Recognized in the Past Two Decades
Acanthamebiasis
Australian bat lyssavirus
Babesia, atypical
Bartonella henselae
Ehrlichiosis
Encephalitozoon cuniculi
Encephalitozoon hellem
Enterocytozoon bieneusi
Hendra or equine morbilli virus
Human herpesvirus 8
Human herpesvirus 6
Parvovirus B19
Group II—Re-emerging Pathogens
Enterovirus 71
Clostridium difficile
Mumps virus
Streptococcus, Group A
Staphylococcus aureus
Group III—Agents with Bioterrorism Potential
See the full list of NIAID Category A, B, and C Priority Pathogens.