ATI Pharm Drug list by Category (8-08)
Drugs used to Treat infection (p. 32):
Penicillins
 Penicillin G-infection
 Methicillin (staphcillin) & Nafcillin (Unipen) –Penicillinase-resistant penicillins
 Amoxicillin (Amoxil) & Ampillicin (Polycillin)—broad spectrum penicillins
 Piperacillin (Pipracil) & Carbenicillin (Geopen)—extended spectrum penicillins
 Amoxicillin + clavulanic acid (Augmentin)—combo drug to protect penicillins from enzymes
Cephalosporins
1st generation
 Cefazolin Na (Ancef, Kefzol)—protype: IM or IV
 Cephalexin (Keflex)—oral preparation
nd
2 generation
 Cefoxitin (Mefoxin), Cefotetan (Cefotan), IM/IV; Cefprozil (Cefzil), Cefaclor (Ceclor),
PO; Cefuroxime (Zinacef) PO/IV/IM
3rd generation—able to penetrate the blood-brain barrier sufficiently to treat CNS infections
 Cefoperazone (Cefobid), Ceftriaxone Na (Rocephin), Cefotaxime (Claforan),
Ceftazidime (Fortaz) IV/IM; Cefixime (Suprax) oral suspension or tablets
th
4 generation—most stable and active against gram +/–
 Cefepime (Maxipime)
Aminoglycosides—narrow spectrum, good for gram –
 Steptomycin Amikacin
 Gentamicin
 Neomycin
Tetracyclines
 Achromycin
 Doxycycline (Vibramycin)
Sulfonamides and Urinary Tract Antiseptic Agents
 Sulfisoxazole (Gantrisin), sulfadiazine (Microsulfon)—short acting drugs
 Trimethoprim/sulfamethoxazole (TMP/SMZ, Bactrim, Septra)—medium acting drugs
 Sulfadoxine (Fansidar), sulfamylon (treats burns) mixed with pyrimethamine (Daraprim)
[antimalarial]–to treat malaria; both are ultra-long acting
 Nitrofurantoin(Furadantin)&Nitrofurantoin macrocrystals(Macrodantin)—treat UTIs
Macrolides
 Erythromycin
 Azithromycin (Zithromax
Lincosamides
 Clindamyhcin (Cleocin)
Fluoroquinolones
 Norfloxacin (Noroxin)—UTIs
 Ciprofoxacin (Cipro) –UTIs
 Enoxacin (Penetrex)—UTIs
 Lomefloxacin (Maxaquin) –UTIs
 Levofloxacin (Levaquin) –UTIs and pneumonia
Antitubercular drugs
 Isoniazid (INH)—1st line—most effective with least toxicity
 Ethambutol— 1st line
 Rifampin— 1st line
 Pyrazinamide— 1st line
 Ethionamide (Trecator-SC) —2nd line—very toxic
 Para-aminosalicylic acid (PAS) —2nd line
 Cycloserine (Seromycin)—2nd line
 Streptomycin (an aminoglycoside used to increase activity of ethambutol and isoiazid)
Special Antibiotics:
 Chloramphenicol (chloromycetin)—life threatening infections that are resistant to other
antibiotics
 Vancomycin (Vancocin)—severe infections from penicillin-resistant Staphylococci
Antivirals
 Acyclovir (Zovirax)—Herpes simplex type I & II, varicella-zoster virus (VZV)
 Amantadine (symmetrel)— respiratory syncytial virus
 Foscarnet (Foscavir)— tx cytomegalovirus retinits (CMV) in persons w/immune deficiency
 Ganciclovir (Cytovene)—tx CMV retinits in persons w/immune def & herpes virus
 Interferons (alsph, beta, gamma)—tx leukemias, renal cell carcinoma, hepatitis, Kaposi's
sarcoma
For treatment of AIDS
 Azidothymidine (AZT, Zidovudine, Retrovir)— (NRTI)—most important drug
 Zalcitabine (Hivid), Stavudine (Zerit/d4T), Didanosine (Videx) — NRTI Antiviral—
 Delavirdine mesylate (Rescriptor), Nevirapine (Viramune)--NNRTI
 Saquinavir (Invirase), Ritonavir (Norvir), Indinavir (Crixivan) —protease inhibitor
Antifungals
 Amphotericin B (Fungizone)— one of most toxic—for life threatening infections
 Flucytosine (Ancobon)— tx serious systemic fungal
 Nystatin (Mycostatin)—orally, topically, vaginally
 Fluconazole (Diflucan)—several uses—well tolerated
 Ketoconazole (Nizoral)— cutaneous fungal infections
 Miconazole (Monistat)— tx vaginal candidiasis
Antiparasitics
 Paromomycin (Humatin)— amebicide
 Metronidazole (Flagyl)—tx anaerobic organisms (Helicobacter pylori, Clostridium difficile,
amebiasis, giardiasis, trichomoniasis)
Antimalarial drugs:
 Chloroquine (Aralen)—
 Quinine sulfate (Quinamm)—
 Hydroxychloroquine (Plaquenil)—
 Mebendazole (vernox)— anthelmintic—tx— roundworms, hookworms, pinworms
 Pyrantel Pamoate (Pin-X)— anthelmintic—tx pinworms
 Pentamindine –antiprotozoal—tx lung infections from parasite protozoa
 Gamma Benzin Hexachloride (Kwell)— scabicide
 Lindane (Nix) –pediculicide
Drugs affecting the immune system (p. 68):
Active Immunizing agents
Bacterial vaccines
 bacillus calmette-guerin (BCG)
 pneumococcal polysaccharide
 Haemophilus B
 Cholera
 typhoid
 anthrax
Viral vaccines
 Hepatitis A & B
 poliovirus
 influenza
 mixed respiratory
 Measles/Mumps/Rubella (MMR)
 Varicella
 Smallpox
Toxoids
 tetanus
 diphtheria
 diphtheria/tetanus/pertussis (DTP), Diphtheria/tetanus/acellular pertussis (DtaP)
Passive Immunizing agents
Immune globulins
 tetanus
 hepatitis B
 cytomegalovirus
 Varicella-zoster
 RhoD (RhoGam)
 rabies
 vaccinia (VIG)
 RSV
Antitoxins
 tetanus
 diphtheria
Immunostimulants
colony-stimulating factors
 Epoetin Alfa (Epogen)—
 Granulocyte colony-stimulating factor, Filgrastim (Neupogen)
Interferons
 Interferon-alpha (Roferon-A)—
 Interferon-beta (Betaseron)
 Interferon-gamma (Actimmune)
Interleukins
 Interleukin-2 (aldesleukin) (IL-2)
Immunosuppressants
Cytotoxic agents
 Azathioprine
 Methotrexate
Conventional antirejection agents
 Cyclosporin—prevent rejection reaction for inhibiting T & B lymphocytes
 Mycophenolate—prevent rejection of cardiac and renal transplants
 Tacrolimus—prevent rejection reactions and treat autoimmune disease
Corticosteroids—suppress growth of all lymphoid tissue   fxn of antibodies and T cells
Antibody preparations
 Polyclonal antibodies, Monoclonal antibodies, Muromonab-CD3 (Orthoclone OKT3)
Other
 Etanercept (Enbrel)—(DMARD)—antirheumatic agent
 Leflunomide (Arava) —(DMARD)—antirheumatic agent
Drugs used to treat HIV and AIDS—see drugs to treat infection/antiviral/used to treat AIDS
Drugs for Pain and Inflammation (p. 87):
Narcotic (opiate) Agonist
 Morphine sulfate—natural opium alkaloid——
 Codeine sulfate—natural opium alkaloid
Semisynthetic analog—narcotic (opiate) Agonist
 Hydromorphone (Dilaudid)
 Oxycodone (Percocet [w/acetaminophen] & Percodan [w/ aspirin]
Synthetic compound narcotic (opiate) Agonist
 Meperidine (Demerol)
 Fentanyl (Sublimaze)
 Methadone Hydrochloride (Dolophine)
 Mixtures
o Brompton's cocktail—mix of morphine, cocaine, dextroamphetamine, & alcohol
Narcotic (opiate) Agonist-Antagonist
 Pentazocine (Talwin, Talwin-Nx)
 Nalbuphine Hydrochloride (Nubain)
 Dezocine (Dalgan)
 Butorphanol (Stadol)
 Buprenorphine (Buprenex)
Narcotic antagonist
 Naloxone (Narcan) ANTIDOTE
 Nalmefene Hydrochloride (Revex)
Non-Narcotic analgesic
 Acteaminophen (Tylenol) [antidote-acetylcysteine (Mucomyst)]
Antiinflammatory/antipyretic
 Acetylsalicylic acid (aspirin)——
 NSAIDS (nonsteroidal anti-inflammatory drugs)
o Ibuprofen (Advil, Motrin)—
o Naproxen (Naproxyn, Advil)
o Ketorolac (Toradol)
o Piroxicam (Feldene)
o Phenylbutazone (Butazolidin)
 Selective COX-2 inhibitor
o Valdecoxib (Bextra)
Anti-inflammatory Corticosteroids
Systemic
 Cortisone (Cortone)—
 Prednisone (Deltasone)
 Betamethasone (Celestone)
 Fludrocortisone (Florinef Acetate)
Topical
 Hydrocortisone (Cortaid)
Inhaled
 Beclomethasone (Vanceril)
Opthalmic
 Prednisolone (AK-Pred)
Anti-migraine
 Ergotamine tartrate (Ergostat)
 Triptan
o Sumatriptan (Imitrex)
o Zolmitriptan (Zomig)
o Rizatriptan (Maxalt)
 Serotonin antagonist
o Methysergide (Sansert)
Anti-gout drugs
o Colchicine
o Ibuprofen (Advil, Motrin, Nuprin)
o Naproxen (Naprosyn)
o Allopurinol (Zyloprim)
o Probenecid (Benemid)
o Sulfinpyrazone (Anturane)
Disease-Modifying Antirheumatic Drugs (DMARDs)
o Gold compounds
o Gold Sodium Thiomalate (Myochrysine)
o Aurothioglucose (Solganal)
o Auranofin (Ridaura)
o Organic gold compounds
o D-penicillamine (Cuprimine) —chelating agent
o Chloroquine hydrochloride (Aralen)—anti-malarial drug—
o Methotrexate (Rheumatrex)—cytotoxic drug
o Azathioprine (Imuran)—cytotoxic drug
o Cyclophosphamide (Cytoxan)
o Cyclosporine (Neoral)—immunosuppressant
Drugs affecting the Nervous System (p. 115):
Adrenergic (sympathomimetic) drugs
Catecholamine drugs
o Ephinephrine hydrochloride (Adrenalin chloride)—prototype of adrenergics
o Norephinephrine (Levophed)—potent vasoconstrictor (for hypotension & cardiac arrest)
o Dopamine hydrochloride (Intropin)—effects related to dosage level
o Dobutamine hydrochloride (Dobutrex)—increases force of contraction of heart muscle
Isoproterenol hydrochloride (Isuprel)—used for shock & some dysrhythmias
Non-catecholamine drug
 Ephedrine
 Pseudoephedrine (Sudafed)
 Phenylephrine HCl (Neo-Synephrine)
 Aubuterol (Proventil)
Alpha-adrenergic blocking agent
o Phentolamine mesylate (Regitine)
o Ergotamine tartrate (Ergostat) and w/caffeine (Cafergot)
o Doxazosin (Cardura)
o Prazosin (Minipress)
o Terazosin (Hytrin)
o Sumatriptan (Imitrex)
Beta-adrenergic blocking agent
o Propranolol Hydrochloride (Inderal)
o Metoprolol tartrate (Lopressor)
o Atenolol (Tenormin)
o Sotalol (Betapace)
o Timolol maleate (Timoptic)
Ganglionic blocking agents
o Mecamylamine HCl (Inversine)
Drugs that affect Parasympathetic Nervous System (PNS)
o Direct-acting cholinomimetic agents
o Acetylcholine
o Bethanechol Cl (Urecholine) –used for urinary retention/atony & open-angle glaucoma
o Pilocarpine HCl (Miostat)—used to lower intraocular pressure
o Carbachol intraocular (Miostat)—simple and open-angle glaucoma
o Metoclopraminde HCl (Reglan)—prevent nausea/vomiting
o Indirect-acting cholinomimetic agent
o Neostigmine bromide (Prostigmin)
o Edrophonium Cl (Tensilon)
o Pyridostigmine bromide (Mestinon)
o Atropine sulfate (ANTIDOTE) for cholinergic Agents
Anticholinergic drugs
o Atropine sulfate—dries secretions, treat bradycardia, antidote for cholinergic drugs &
insecticide poisoning
o Belladonna tincture—treat GI disorders
o Homatropine (Spectro-Homatropine)—produces mydriasis & cycloplegia
o Trihexyphenidyl (Artane)—treat parkinson's disease
o Oxybutynin Cl (Ditropan)— bladder capacity &  frequency of voiding
o Scopolamine hydrobromide (Hyoscine)—treat Nausea/Vomiting
Drugs that Affect the Neuromuscular System
o Central Skeletal Muscle Relaxants
o Carisoprodol (Soma)—
o Cyclobenzaprine HCl (Flexeril)
o Baclofen (Lioresal)
o Orphenadrine (Norflex)
o Direct-acting skeletal muscle relaxant
o Dantrolene Na (Dantrium)
Nondepolarizing neuromuscular blocking agent
o Pancuronium bromide(Pavulon)——
o Vecuronium Br (Norcuron)
o Tubocurarine Cl (Tubarine)
o Atracurium (Tracrium)
o Rocuronium (Zemuron)
o Mivacurium (Mivacron)
Depolarizing neuromuscular blocking agent—
o Succinylcholine (Anectine)
Drugs that stimulate the Central Nervous System (CNS)
o Analeptic stimulant
o Caffeine
o Doxapram HCl (Dopram)
o Theophylline—a methylxanthine
o Psychomotor stimulant
o Methylphenidate (Ritalin)—for narcolepsy and ADHD
o Premoline (Cylert)—ADHD
o Amphetamine sulfate—narcolepsy and ADHD
o Methamphetamine HCl (Desoxyn)—ADHD and obesity
o Dextroamphetaminhe sulfate (Dexedrine)—narcolepsy and ADHD
o Nonamphetamine anorexiant
o Phentermine HCl (Fastin)
o Phenmetrazine (Preludin)
o Diethylpropion HCl (Tenuate)
Drugs that depress the Central Nervous System (CNS)
o Barbiturates
o Thiopental Na (Pentothal)
o Phenobarbital Na (Luminal, Nembutal)
o Secobarbital Na (Seconal)
o Amobarbital (Amytal)
o Non-barbiturates
o Buspirone (BuSpar)— anxiolytic
o Chloral hydrate (Noctec)
o Zolpidem tartrate (Ambien)
o Paraldehyde (Paral)
o Hydroxyzine (Vistaril)
o Diphenhydramine HCl (Benadryl)
o Benzodiazepines--- Flumazenil Romazicon—ANTIDOTE—Benzodiazepine antagonist
o Temazepam (Restoril)—
o Diazepam (Valium)
o Clonazepam (Klonopin)
o Flurazepam HCl (Dalmane)
o Estazolam (ProSom)
o Quazepam (Doral)
o Triazolam (Halcion)
o Anxiolytic
o Benzodiazepines—Diazepam (Valium), Chlordiazepoxide (Librium), Halazepam
(Paxipam), Lorazepam (Ativan), Prazepam (Centrax)
o Buspirone (BuSpar)— anxiolytic
o Chloral hydrate (Noctec)
o Zolpidem tartrate (Ambien)
o Diphenhydramine HCl (Benadryl)
Mood disorder drugs
o Cyclic antidepressant
o Imipramine HCl (Tofranil)——
o Amitriptyline HCl (Elavil)
o Doxepin HCl (Sinequan)
o Maprotiline (Ludiomil)
o Selective serotonin reuptake inhibitor (SSRI)
o Fluoxetine (Prozac)
o Sertraline (Zoloft)
o Paroxetine (Paxil)
o Monoamine Oxidase inhibit. (MAOI)
o Phenelzine sulfatge (Nardil)
o Tranylcypromise sulfate (Parnate)
o Mood stabilizing drugs
o Lithium carbonate (Eskalith, Lithane, Lithonate)—normal serum levels (0.6-1.2)
o Lithium citrate syrup (Cibalith-S)
Psychiatric disorder Drugs
o Phenothiazines
o Chlorpromazine (Thorazine, Ormazine)——
o Fluphenazine (Permitil, Prolixin)
o Trifluoperazine (Stelazine, Suprazine)
o Non-Phenothiazines
o Thiothixene (Navane)
o Haloperidol (Haldol)
o Clozapine (Clozaril)
o Molindone (Moban)
o Loxapine (Loxitane)
o Risperidone (Risperdal)
o Olanzapine (Zyprexa)
Drugs that treat seizures
o Barbiturates
o Phenobarbital Na (Luminal)
o Primidone (Mysoline)
o Hydantoins
o Phenytoin (Dilantin)
o Fosphenytoin (Cerebyx)
o Mephenytoin (Mesantoin)
o Benzodiazepine
o Clonazepam (Klonopin), Diazepam (Valium), Lorazepam (Ativan, Alzapam),
Clorazepate (Tranxene)
o Other anti-convulsants
o Carbamazepine (Tegretol)
o Ethosuximide (Zarontin)
o Felbamate (Felbatol)
o Gabapentin (Neurontin)
o Lamotrigine (Lamictal)
o Phensuximide (Milontin)
o Primidone (Mysoline)
o Trimethadione (Tridione)
o Valproic acid (Depakene)
Neurological Disorder Drugs
o dopaminergic drugs
o Levodopa (Dopar, Larodopa)—— Parkinson's disease
o Carbidopa-levodopa (Sinemet) —Parkinson's disease
o Anticholinergic/antimuscarinic
o Trihexyphenidyl (Artane)
o Benztropine (Cogentin)
o Antiparkinson Drugs
o Amantadine (Symmetrel) —dopamine receptor agonist
o Pergolide (Permax) —dopamine receptor agonist
o Pramipexole (Mirapex) —nonergot dopamine receptor agonist
o Ropinirole HCl (Requip) —nonergot dopamine receptor agonist
o Bromocriptine (Parlodel) —dopamine receptor agonist
o Selegiline HCl (Eldepryl)—MAOI—type B
o Entacapone (Comtan)—inhibits an enzyme that breaks down levodopa
Myasthenia Gravis Drugs
Atropine Sulfate is ANTIDOTE
o Neostigmine Br (Prostigmin)—Cholinergic/anti-cholinesterase —
o Edrophonium Cl (Tensilon) —Cholinergic/anti-cholinesterase
o Pyridostigmine Br (Mestinon) —Cholinergic/anti-cholinesterase
Inhalation anesthesia
o Nitrous oxide (N2O)
o Halothane (Fluothane)
o Methoxyflurane (Penthrane)
o Enflurance (Ethrane)
Intravenous anesthesia—
o Fentanyl citrate (Sublimaze) —opioid—
o Thiopental sodium (Pentothal)—barbiturate
o Methohexital Na (Brevital) —barbiturate
o Ketamine (Ketalar) —Non-barbiturate
o Propofol (Diprivan
Local/regional anesthesia
o Esters
o Procaine (Novocaine)
o Benzocaine—Ester
o Tetracaine HCl (Pontocaine)
o Amides
o Lidocaine (Xylocaine)
o Prilocaine (Citanest)
o Mepivacaine (Carbocaine)
o
Drugs affecting the Cardiovascular System (p. 197):
Heart failure drugs
o adrenergic (sympathomimetic drug)
o Digoxin—caridac glycoside—
o Digitoxin (Crystodigin) —adrenergic (sympathomimetic drug)—heart failure
o Digoxin Immune Fab (Digibind)—ANTIDOTE for digoxin
o cardiotonic-inotropic agent
o Amrinone (Inocor)—bipyridine derivative
o Milrinone (Primacor) —bipyridine derivative—cardiotonic-inotropic agent
o Nesiritide (Natrecor)—vasodilator—brain natriuretic peptide (BNP)
Angina Drugs
o Organic nitrates
o Nitroglycerine (NTG) (Nitro-bid, Nitrostat, Nitrodisc, Nitrogard, Nitro-Dur)
o Isosorbide dinitrate (Isordil) —organic nitrate
o Beta-Adrenergic blockers
o Propranolol HCl (Inderal)
o Atenolol (Tenormin)
o Pindolol (Visken)
Calcium channel blockers
o Verapamil HCl (Calan, Covera-HS, Isoptin,k Verelan)
o Nefedipine (Adalat, Nifedical, Procardia)
o Diltiazem HCl (Cardizem)
o Amlodipine (Norvasc)
o Nicardinine HCl (Cardene SR)
Lipid lowering drugs
o Bile acid sequestrants
o Colestipol (Colestid)—bile acid sequestrant
o Cholestyramine (Questran, Prevalite Powder)
o HMG-CoA reductase inhibitor (statins)
o Atorvastatin (Lipitor)
o Simvastatin (Zocor)
o Fluvastatin (Lescol)
o Pravastatin (Pravachol)
o Lovastatin (Mevacor)
o Fibric Acid derivative
o Gemfibrozil (Lopid)
o Fenofibrate (Lipidil)
Dysrhythmia drugs
o Group 1A—Na channel blocker
o Quinidine sulfate (Cin-Quin, Quinora
o Procainamide HCl (Pronestyl)
o Disopyramide phosphate (Norpace)
o Group 1B—decreases action potential
o Lidocaine HCl (Xylocaine)
o Mexiletine HCl (Mexitil)
o Tocainide HCl (Tonocard)
o Group 1C—cell membrane stabilizer
o Propafenone HCl (Rythmol)
o Flecainide acetate (Tambocor)
o Group II—Beta-adrenergic blockers
o Propranolol HCl (Inderal)——
o Esmolol HCl (Brevibloc)—
o Sotalol (Betapace)
o Metoprolol (Lopressor)
o Acebutolol (Monitan)
o Group III—potassium channel blocker
o Bretylium tosylate (Bretylol)
o Amiodarone (Cardarone)
o Ibutilide (Covert)
o Group IV—Calcium Channel blockers (CCB)
o Verapamil HCl (Calan, Isoptin)
o Diltiazem HCl (Cardizem)
Hypertension Drugs
o Angiotension-Converting Enzyme (ACE) Inhibitors
o Captopril (Capoten)—
o Lisinopril (Prinivil)
o Enalapril maleate (Vasotec)
o Quinapril HCl (Accupril)
o Moexipril HCl (Univasc)
o Ramipril (Altace)
o Fosinopril (Monopril)
o angiotensin-II receptor antagonist
o Losartan potassium (Cozaar)
o Beta adrenergic blocker
o Propranolol HCl (Inderal)——
o Atenolol (Tenormin)
o Acebutolol (Monitan)
o Metoprolol tartrate (Lopressor)
o Labetalol (Normodyne, Trandate)
o Calcium channel blocker (CCB)
o Nifedipine (Procardia)
o Amlodipine besylate (Norvasc)
o Diltiazem HCL (Cardizem)
o Verapamil HCL (Isoptin)
o Felodipine (Plendil)
Other Anti-hypertensive Agents
o Alpha-adrenergic blocking agent
o Prazosin HCl (Minipress)——
o Reserpine (Serpasil, Sandril)
o Sympathetic NS inhibitor
o Clonidine HCl (Catapres)——
o Direct-acting vasodilator
o Hydralazine (Apresoline)——
o Minoxidil (Loniten)
o Diazoxide (Hyperstat)
o mixed arterial/venous vasodilator
o Sodium Nitroprusside (Nipride)——
Hypotension/shock drugs
o Adrenergic drugs
o Epinephrine HCl (Adrenalin)
o Norephinephrine (Levophed)
o Dopamine HCl (Intropin)
o Dobutamine HCl (Dobutrex)
o Isoproterenol HCl (Isuprel)
Drugs affecting the Blood (p.256):
Anticoagulants
o Heparin sodium
(Protamine sulfate—ANTIDOTE)
o Low molecular weight heparin (LMWH)
 Enoxaparin (Lovenox)
 Dalteparin (Fragmin)
 Danaparoid (Orgaran)
 Ardeparin (Normiflo)
o Warfarin (Coumadin)
(ANTIDOTE is Vit K)
o Anti-anemics
o Epoetin Alpha (Epogen, EPO, Procrit)—erthropoietin—
o thrombolytic
o Alteplase (Activase)——
o Anistreplase (Eminase)
o Streptokinase (Streptase)
o Urokinase (Abbokinase)
o antiplatelet
o Acetylsalicylic acid (Aspirin)
o Dipyridamole (Persantine)
o Ticlopidine (Ticlid)
o Abciximab (ReoPro)
o Clopidogrel (Plavix)
o Eptifibatide (Integrillin)
o Tirofiban ( Aggrastat)
Blood Chelation (to reduce Iron levels in the bloodstream)
o Ethylenediaminetetraacetic acid aka Ca disodium edentate [EDTA]—
o Succimer (Chemet)
Drugs affecting the Respiratory System (p. 283):
Antihistamines
o Fexofenadine (Allegra)——rhinitis
o Loratadine (Claritin)—seasonal allergies
o Cetirizine (Zyrtec)—allergic rhinitis & urticaria
o Dimenhydrinate (Dramamine)—motion sickness
o Meclizine (Antivert)—motion sickness
o Promethazine (Phenergan) —N/V, increase CNS depression
o Hydroxyzine (Vistaril)—N/V, increase CNS depression
o Diphenhydramine HCl (Benadryl)—allergic response, promote sleep
Antitussive
o Codeine—opioid
o Dextromethorphan—Non-opioid
Bronchodilators—adrenergic
o Albuterol (Proventil)—adrenergic
o Salmeterol (Serevent Diskus)—adrenergic
o Terbutaline (Berethine) —adrenergic bronchodilator
o Levalbuterol (Xopenex) —adrenergic bronchodilator
o Epinephrine—acute bronchoconstriction
o Theophylline (Theo-Dur)—xanthine bronchodilator
o Aminophylline (Phyllocontin) —xanthine bronchodilator
o Ipratropium (Atrovent)—anticholinergic bronchodilator
Decongestants
o Pseudoephedrine (Sudafed, novafed, Afrinol Repetabs)
o Oxymetazoline (Afrin)
o Phenylephreine (Neo-synephrine)
Expectorants
o Guaifenesin (Robitussin)
Inhaled corticosteroid
o Belcomethasone
o Budesonide (Pulmicort)
o Triamcinolone (Azmacort)
o Fluticasone (Flovent)
o Flunisolide (AeroBid)
Leukotriene Modifiers
o Zafirkulast (Accolate)
o Montelukast (Singulair)
Mast Cell Stabilizer
o Cromolyn Sodium (Intal)
Mucolytic
o Acetylcysteine (Mucomyst)
Drugs affecting the Renal System (p.303):
Carbonic Anhydrase Inhibitor
o Acedtazolamide (Diamox, Daxamide)——diuretic
o Dorzolamide (Trusopt)—diuretic
o Brinzolamide (Azopt)—diuretic
Loop (high ceiling) Diuretics
o Furosemide (Lasix)——Renal System
o Ethacrynic acid (Edecrin) —Loop diuretic —Renal System
o Bumetanide (Bumex) —Loop diuretic —Renal System
o Torsemide (Demadex) —Loop diuretic —Renal System
Osmotic diuretic
o Mannitol (Osmitrol)
Potassium-sparing diuretics
o Spironolactone (Aldactone)
o Triamterene (Dyrenium)
o Amiloride (Midamor)
Thiazide and related diuretics
o Hydrochlorothiazide (HydroDIURIL)--thiazide
o Chlorothiazaide (Diuril) —Thiazide
o Bendroflumethiazide (Naturetin) —Thiazide
o Methyclothiazide (Enduron) —Thiazide
o Chlorthilidone (Hygroton, Thalitone) — diuretic
o Indapamide (Lozol) — diuretic
o Metolazone (Zaroxolyn, Mykrox)—diuretic
o Quinethazone (Hydromox)—diuretic
Drugs that affect the Digestive System (p. 316):
Antiacids
o Aluminum hydroxide
o Magnesium hydroxide
o Calcium Carbonate
o Sodium Bicarbonate
Antidiarrheals
o Lomotil (diphenoxylate)—opiate
o Loperamide (Imodium)
o Psyllium (Fiberall) aka Metemucil
Antiemetics
o Ondansetron (Zofran)—selective serotonin antagonist
o Granisetron (Kytril) —selective serotonin antagonist
o Dolasetron (Anzemet) —selective serotonin antagonist
o Chlorpromazine (thorazine)—phenothiazine —dopamine antagonist
o Prochlorperazine (Compazine) —phenothiazine —dopamine antagonist
o Promethazine (Phenergan) —phenothiazine —dopamine antagonist
o Meclizine (Antivert) —antihistamine—motion sickness/vertigo
o Dimenhydrinate (Dramine) —antihistamine—motion sickness/vertigo
o Methylprednisolone (Solu-Medrol) —glucocorticoid
o Dexamethasone (Decadron) —glucocorticoid
o Lorazepam (Ativan)—benzodiazepine
Antiflatulent
o Simethicone (Mylicon)——
Antiulcer Drugs
o Histamine2-receptor antagonist
o Ranitidine (Zantac)
o Ranitidine Bismuth citrate (Tritec)
o Famotidine (Pepcid)
o Nizatidine (Axid Pulvules, Axid AR)
o Cimetidine (Tagamet)
o Proton Pump Inhibitor
o Omeprazole (Prilosec)
o Lansoprazole (Prevacid)
o Rabeprazole (Aciphex)
o Pantoprazole (Protonix)
o Sucralfate
o Sucralfate (Carafate)
o prostaglandin
o Misoprostol (Cytotec)
Emetics
o Syrup of Ipecac
Gastrointestional (GI) stimulants
o Metoclopramide (Reglan)——
Laxatives
o Metamucil—bulk-forming laxative
o Bran cereals—bulk-forming laxative
o Docusate Sodium—surfactant laxative
o Milk of Magnesia (MOM)—saline cathartic
o Magnesium Citrate—saline cathartic
o Bisocodyl (Dulcolax)—stimulant laxative
o Castor Oil—stimulant laxative
o Ex-Lax—stimulant laxative
o Glycerin suppository—hyperosmotic agent—laxative
o Lactulose (Constulose)—hyperosmotic agent—laxative
o Mineral oil—Lubricant laxative
o Polyethylene glycol-electrolyte solution (GlLYTELY, CoLyte)
Vitamins
o Fat-soluble—A, D, E, & K
o Water-soluble—B1 (Thiamin), B2 (Riboflavin), B3 (Niacin) ,B5 (Pantothenic acid), B6
(Pyridoxine) ,B9 (Folic acid), B12 (Cyanocobalamin), Biotin
Drugs affecting the Endocrine System (p. 338):
Antiglycemics
o Biguanides ( hepatic production of glucose)
o Metformin (Glucophage)
o Alpha-Glucosidase inhibitor ( rate of complex CHO metabolism  glucose absorption
following meals)
o Acarbose (Precose)
o Miglitol (Glyset)
o Thiazolidinediones ( insulin resistance & enhances insulin action)
o Pioglitazone (Actos)
o Rosiglitazone (Avandia)
o Sulfonylurea (stimulates pancreas to release more insulin)—see hyperglycemic hormones for list
Anti-thyroid
o Thioamides
o Radioactive iodine 131I
Corticosteroids
o Cortisone (Cortone)—systemic
o Prednisone (Deltasone) —systemic
o Betamethasone (Celestone) —systemic
o Fludrocortisone (Florinef Acetate) —systemic
o Dexamethasone (Decadron) —systemic
o Hydrocortisone—topical
o Beclomethasone (Vanceril) —inhaled
o Prednisolone (AK-Pred) —ophthalmic
Hormones
o Estrogen
o Conjugated (equine, synthetic), DES (diethylstilbestrol), Estradiol, Estrone, Estropipate,
Ethinyl estradiol
o Progesterone
o Progesterone injectable (IM)
o Prometrium micronized capsules
o Norethindrone (w/ estradiol) transdermal
o Medroxprogesterone acetate (Provera)
o Crinone micronized vaginal cream
o Androgens
o Testosterone cypionate (Depo-Testosterone)
o Testosterone enanthate (Andro LA)
o Testosterone ppropionate (Testex)
o Danazol (Danoccrine)
o Nandrolone decanoate (Deca-Durabolin)—anabolic steroid
o Stanozolol (Winstrol)—anabolic steroid
o Antiandrogens
o Flutamide (Eulexin)
o Bicalutamide (Casodex)
o Nilutamide (Nilandron)
Hyperglycemic hormones
o Glucogon
o Sulfonlureas ( insulin release from the pancreas)
o 1st generation: Tolbutamide (Orinase), Acetohexamide (Dymelor), Tolazamide
(Tolinase), Chlorpropamide (Diabinese)— rarely used
o 2nd generation: Glipizide (Glucotrol), Glyburide (DiaBeta, Glynase PresTab, Micronase)
Glimepiride (Amaryl)
o Meglitinides ( insulin release from the pancreas right after a meal)
o Repaglinide (Prandin)
o D-phenylalanine derivative ( insulin release from the pancreas right after a meal)
o Nateglinide (Starlix)
o Combination Oral Drugs
o Glyburide/Metformin (Glucovance) —sulfonylurea/biguanide
Hypoglycemics (agents that aim at lowering blood glucose levels)
o Insulin
o Rapid-acting—onset 10-20 min.; Peak ½ to 3 hrs; Duration 3-5 hrs
 Insulin Lispro (Humalog)
 Insulin Aspart (NovoLog)
o Short-acting —onset ½ -1 hr.; Peak 1-5 hrs; Duration 6-10 hrs
 Regular R
o Intermediate-acting —onset 1-3 hrs.; Peak 6-10 hrs; Duration up to 24 hrs
 NPH (Humulin N)
 Lente
o Long-acting
 Ultralente—onset 4-6 hrs.; Peak 18-20 hrs; Duration 24-28 hrs
 Glargine (Lantus) —onset 5 hrs.; No Peak; Duration > 24hrs
Immunosuppressants
o Azathioprine (Rheumatrex, Trexall)—rheumatoid arthritis, antirejection—cytotoxic-o Methotrexate (Imuran)—rheumatoid arthritis, psoriasis, cancer—cytotoxic agent
o Cyclosporin (Sandimmune)—antirejection-- conventional antirejection agents
o Mycophenolate (CellCept)—antirejection (cardiac/Renal)—conventional antirejection
agents
o Tacrolimus (Prograf)—antirejection—conventional antirejection agents
o Polycolon antibody—antibody preparations
o Monoclonal antibodies
o Etanercept (Enbrel)
o Leflunomide (Arava)
Immunizations—see immune system drugs
Thyroid agents
o Levothyroxine (Synthroid, Levoxyl, Levothroid)—
o Liothyronine (Cytomel)
Drugs affecting Reproduction (p. 374):
Ovulation suppressants
o Lestrin
o Lo-Ovral
o Nordette
o Ovral,
o Ortho-Novum
o Micronor
Ovulation stimulants
o Clomiphene citrate (Clomid)—
o Bromocriptine mesylate (Parlodel)
o Leuprolide (Lupron)
Estrogens
o Steroidal
 Conjugated estrogens (Premarin)
 Estradiol (Estrace)
 Estropipate (Ogen)
o Non-steroidal
 Chlorotrianisene (TACE)
 Diethylstibestrol (DES)
Progestins
 Medroxyprogesterone injections (Provera, Depo-Provera)
 Progesterone intrauterine (Progestasert)
 Megestrol acetate (Megace)
 Levonorgestrel implants (Norplant)
Androgens
o Fluoxymesterone (Halotestin)
o Testosterone (Depo—Testosterone)
o Danazol (Danocrine)
Drugs affecting the Integumentary System (p. 386):
Antiseptics & Disinfectants
o Iodine tincture, Iodine topical
o Betadine solution
o Triclosan (Septi-soft, Septisol)
o Benzalkonium Chloride (Benza)
o Chlorhexidine Gluconate (Hibiclens, Peridex)
o Hexachlorophene (pHisoHex, Septisol)
o Glutaraldehyde (Cidex)
o Formaldehyde
o Silver Nitrate
o Hydrogen Peroxide
o Thimerosal (Mersol)
Soaps & Cleaners
o Neutrogena, Zest, Dove, Cold Cream, Lanolin, Caress, Ivory, pHisoderm, Aveeno, Nivea
Emollients and Protectants (excluding sunscreen)
o Aluminum Sulfate (Domeboro)
o Tucks
o Aquaphor
o Eucerin Cream
o Lubriderm
o A&D Opintment
o Lanoline
o Pedtroleum Jelly
o Benzoin
o Destine & KY Products
Wet Dressings, Soaks, Rubs & Liniments
o Calamine Lotion or Calamine with phenol
o Diphenhydramine hydrochloride (Benadryl) lotion and cream
o Aluminum acetate solution (Burow's Solution)
o Aluminum sulfate (Domeboro)
o Vlemasquie, Aspercreme, Bengay ointments, and Vicks
Prophylactic Agents
o Benzoin, Kerodex, Hawaiinb Tropic, Coppertone, Sundown, Kipkote by Coppertone, PreSun
Lip Portector
Anti-infectives
o Bacitracin (Baciguent)
o Polymyxin (Polysporin)
o Chlortetracycline hydrochloride (Aureomycin)
o Clindamycin phosphate (Cleocin T)
o Erythromycin (Erygel, EryDerm)
o Mafedide acetate (Sulfamylon)
o Mupirocin (Bactroban)
o Neomycin sulfate (Mycifradin Sulfate Topical)
o Silver sulfadiazine (Silvadene)
Antivirals
o Acyclovir (Zovirax)
o Docosanol (Abreva)
o Penciclovir (Denavir)
Antifungals
o Amphotericin B (Fungizone)
o Butoconazole (Femstat)
o Ciclopirox olamine (Loprox)
o Clioquinol (Vioform)
o Clotrimazole (Gyne-Lotrimin, Mycelex)
o Haloprogin (Halotex)
o Miconazole nitrate (Micatin, Monistat Derm)
o Nystatin (Nilstat, Mycostatin)
o Terbinafine HCL (Lamisil)
o Tolnaftate (Tinactin)
Antiparasitics
o Lindane (Kwell, Scabene, G-Well: in cream, lotion, or shampoo)
o Permethrin (Elimite, Nix)
o Malathion (Ovide)
o Crotamiton (Eurax: lotion and cream)
Topical Corticosteroids
o Dexamethasone (Topicort)
o Fluocinolone Acetonide (Derma-Smoother)
o Hydrocortisone (Cortaid, Lanacort)
o Betamethasone (Valisone)
o Mometasone (Elocon)
Debriding Agents and Keratolytics
o Salicylic acid (Occlusal)
o Tretinoin (Retin-A)
o Anthralin (Dithocreme)
o Sulfer (sebulex)
o Granulex
o Collagenase (Santyl)
o Tazarotene (Avage)
Acne Agents
o Benzolyl peroxide
o Tretinoin (Retin-A)
o Isotretinoihn (Accutane)
o Tetracycline (Acfhromycin V, Actisite)
o Erythromycin (E-mycin, Ilotycin)
o Clindamycin (Cleocin)
Burn Agents
o Silver Sulfadiazine (Silvadene)
o Mafenide acetate (Sulfamylon)
o Mupirocin (Bactroban)
o Gentamycin sulfate (Garamycin)
Antipruritics
o Antipruritic
o Diphenhydramine hydrochloride (Benadryl)
o Doxepin (Zonalon)
o Anti-inflammatory
o Dexamethasone (Topicort)
o Fluocinolone acetonide (Derma-Smoothe / FS)
o Hydrocortisone (Cortaid, Lanocort)
o Betamethasone (Valisone)
o Wet dressings, soaks, rubs, and liniment agents
o Calamine lotion or Calamine with phenol
Diphenhydramine hydrochloride (Benadryl) lotion and cream
o Aluminum acetate solution ( Burow's Solution)
o Aluminum Sulfate (Domeboro)
o Aspercrene, Bengay ointments, Vicks, Banalg liniment
o Other
o Cornstarch
o Oatmeal baths (Aveeno)