Coming Soon Benseñor LB, Wang N, Kan H-M, Mateer SC, Wallrabe H, Davidson L, Schafer DA, and Bloom GS. IQGAP1-Stimullated Actin Assembly Linked to Growth Factor Receptor Activation. King ME, Kan H-M, Baas P, Erisir A, Glabe CG, and Bloom GS. Tau-Dependent Microtubule Disassembly Induced by Pre-fibrillar ß-Amyloid. Chen Y, Benseñor LB, Cheney RE, Goldenring JR, Provance DW, Mercer JA, and Bloom GS. Regulation of Caveolar membrane Trafficking by Myosin Vc. Published Bloom GS. 2006. Intracellular Trafficking and the Cytoskeleton (Editorial). Traffic 7: 489. PDF Cover Picture Morris, LE, Bloom GS, Frierson HF Jr., and Powell SM. 2005. Nucleotide Variants Within the IQGAP1 Gene in Diffuse-Type Gastric Cancers. Genes, Chromosomes and Cancer 42: 280-286. PDF Bloom GS, Ren K, and Glabe CG. 2005. Cultured Cell and Transgenic Mouse Models for Tau Patholgy Linked to ß-Amyloid BIOCHIMICA ET BIOPHYSICA ACTA MOLECULAR BASIS OF DISEASE 1739: 116-124. PDF Bloom GS, King ME, and Binder LI. 2005. Guest Editors for BIOCHIMICA ET BIOPHYSICA ACTA (MOLECULAR BASIS OF DISEASE), Special Issue on The Biology and Pathobiology of Tau (volume 179, issues 2-3). Elsevier Science (Amsterdam). Cover Picture Yamaoka-Tojo M, Ushio-Fukai M, Hilenski L, Dikalov SI, Chen YE, Tojo T, Fukai T, Fujimoto M, Patrushev NA, Wang N, Bloom GS, and Alexander RW. 2004. IQGAP1, a Novel VEGF Receptor Binding Protein Involved in Redox-dependent Endothelial Migration and Proliferation. CIRCULATION RESEARCH 95: 276-283. PDF Mateer ST, Morris LE, Cromer DA, Benseñor LB, and Bloom GS. 2004. Actin Filament Binding by a Monomeric IQGAP1 Fragment with a Single Calponin Homology Domain. CELL MOTILITY AND THE CYTOSKELETON 58: 231-241. PDF Cover Picture 1 Mateer ST, Wang N, and Bloom GS. 2003. IQGAPs: Integrators of the Cytoskeleton, Cell Adhesion Machinery and Signaling Networks. CELL MOTILITY AND THE CYTOSKELETON 55: 147-155. PDF Movie (CV-1 cell expressing IQGAP1-YFP) Mundy DI, Machleidt T, Ying Y-S, Anderson RGW, and Bloom GS. 2002. Control of Caveolar Membrane Traffic by Microtubules and the Actin Cytoskeleton. JOURNAL OF CELL SCIENCE 115: 4327-4339. PDF Movie Legends Movie 1 Movie 2 Movie 3 Movie 4 Movie 5 Movie 6 Movie 7 Movie 8 Mateer SC, McDaniel AE, Nicolas V, Habermacher GM, Lin M-JS, Cromer DA, King ME, and Bloom GS. 2002. The Mechanism for Regulation of the F-actin Binding Activity of IQGAP1 by Calcium/Calmodulin. JOURNAL OF BIOLOGICAL CHEMISTRY 277: 12,324– 12,333. PDF Calcium Response Movie Calcium Reversal Movie Bloom GS. 2001. The UNC-104/KIF1 Family of Kinesins. CURRENT OPINION BIOLOGY 13: 36-40. PDF IN CELL Bloom GS 2000. Guest Editor for BIOCHIMICA ET BIOPHYSICA ACTA (MOLECULAR CELL RESEARCH), volume 1496, (1), Special Issue on Molecular Motors. Elsevier Science (Amsterdam). Cover Picture Sontag E, Nunbhakdi-Craig V, Lee G, Brandt R, Kamibayashi C, Kuret J, White CL III, Mumby MC, and Bloom GS. 1999. Molecular Interactions Among Phosphatase 2A, Tau, and Microtubules: Implications for the Regulation of Tau Phosphorylation and the Development of Tauopathies. JOURNAL OF BIOLOGICAL CHEMISTRY 274: 25490-25498. PDF 2 Fullerton AT, Bau M-Y, Conrad PA, and Bloom GS. 1998. In Vitro Reconstitution of Microtubule Plus End-directed, GTPS-Sensitive Motility of Golgi Membranes. MOLECULAR BIOLOGY OF THE CELL: 2699-2714. PDF Fragments Movie Tubules Movie GTPS Movie Ratner N, Bloom GS, and Brady ST. 1998. A Role for Cyclin-Dependent Kinase(s) in the Modulation of Fast Anerograde Axonal Transport: Effects Defined by Olomoucine and the APC Tumor Suppressor Protein. JOURNAL OF NEUROSCIENCE 18: 7717-7726. PDF Bashour A-M, and Bloom GS. 1998. 58K, a Microtubule-binding Golgi Protein, is a Formiminotransferase Cyclodeaminase (FTCD). JOURNAL OF BIOLOGICAL CHEMISTRY 273: 19612-19617. PDF Bloom GS, and Goldstein LSB. 1998. Cruising Along Microtubule Highways: How Membranes Move Through the Secretory Pathway. JOURNAL OF CELL BIOLOGY 140: 1277-1280. PDF Bashour A-M, Fullerton AT, Hart MJ, and Bloom GS. 1997. IQGAP1, a Rac- and Cdc42-binding Protein, Is An Actin-Binding Protein That Cross-Links Microfilaments. JOURNAL OF CELL BIOLOGY: 137: 1555-1566. PDF Biesiada E, Adams PM, Shanklin DR, Bloom GS, and Stein SA. 1996. Biology of the Congenitally Hypothytroid hyt/hyt Mouse. ADVANCES IN NEUROIMMUNOLOGY 6: 309-346. Sontag E, Nunbhakdi-Craig V, Brandt R, Lee G, Bloom GS, and Mumby MC. 1996. Regulation of the Phosphorylation State and Microtubule-Binding Activity of Tau by Protein Phosphatase 2A. NEURON: 17: 1201-1207. PDF Conrad PA, Smart EJ, Ying Y-S, Anderson RGW, and Bloom GS. 1995. Caveolin Cycles Between Plasma Membrane Caveolae and the Golgi Complex by Microtubuledependent and Microtubule-independent Steps. JOURNAL OF CELL BIOLOGY 131: 14211433. PDF Sontag E, Nunbhakdi-Craig V, Bloom GS, and Mumby MC. 1995. A Novel Pool of Protein Phosphatase 2A is Associated with Microtubules and Regulated During the Cell Cycle. JOURNAL OF CELL BIOLOGY 128: 1131-1144. PDF 3 Elluru R, Bloom GS, and Brady ST. 1995. Fast Axonal Transport of Kinesin in the Rat Visual System: Functionality of the Kinesin Heavy Chain Isoforms. MOLECULAR BIOLOGY OF THE Cell: 6: 21-40. Lippincott-Schwartz J, Cole NB, Marotta A, Conrad PA, and Bloom GS. 1995. Kinesin is the Motor for Microtubule-mediated Golgi-to-ER Membrane Traffic. JOURNAL OF CELL BIOLOGY 128: 293-306. PDF Bloom GS, Richards B, Leopold PL, Ritchey DM, and Brady ST. 1993. GTPS Inhibits Organelle Transport Along Axonal Microtubules. JOURNAL OF CELL BIOLOGY 120: 467476. PDF Leopold PL, McDowall A, Pfister KK, Bloom GS, and Brady ST. 1992. Association of Kinesin with Characterized Membrane-bounded Organelles. CELL MOTILITY AND THE CYTOSKELETON 23: 19-33. Bloom GS. 1992. Motor Proteins for Cytoplasmic Microtubules. CURRENT OPINION CELL BIOLOGY 4: 66-73. PDF IN Wagner MC, Pfister KK, Brady ST, and Bloom GS. 1991. Purification of Kinesin from Bovine Brain and Assay of its Microtubule-Stimulated ATPase Activity. METHODS IN ENZYMOLOGY 196: 157-175. PDF Vallee RB, and Bloom GS. 1991. Mechanisms of Fast and Slow Axonal Transport. ANNUAL REVIEW OF NEUROSCIENCE 14: 59-92. Cyr JL, Pfister KK, Bloom GS, Slaughter CA, and Brady ST. 1991. Molecular Genetics of Kinesin Light Chains: Generation of Isoforms by Alternative Splicing. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA 88: 10114-10118. PDF Hirokawa N, Kobayashi N, Sato-Yoshitake R, Pfister KK, Bloom GS, and Brady ST. 1991. Kinesin Associates with Anterogradely Transported Membranous Organelles In Vivo. JOURNAL OF CELL BIOLOGY 114: 295-302. PDF Ktistakis N, Roth MG, and Bloom GS. 1991. PtK1 Cells Contain a Non-Diffusible Factor that Makes the Golgi Apparatus Resistant to Brefeldin A. JOURNAL OF CELL BIOLOGY 113: 1009-1023. PDF 4 Donaldson JG, Lippincott-Schwartz J, Bloom GS, Kreis TE, and Klausner RD. 1990. Dissociation of a 110 kD Peripheral Membrane Protein from the Golgi Apparatus is an Early Event in Brefeldin A Action. JOURNAL OF CELL BIOLOGY 111: 2295-2306. PDF Leopold PL, Bloom GS, and Brady ST. 1990. Nucleotide Specificity for the Bidirectional Transport of Membrane-bounded Organelles in Isolated Axoplasm. CELL MOTILITY AND THE CYTOSKELETON 15: 210-219. Brady ST, Pfister KK, and Bloom GS. 1990. A Monoclonal Antibody to the Heavy Chain of Kinesin Inhibits Anterograde and Retrograde Axonal Transport in Isolated Squid Axoplasm. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA 87: 1061-1065. PDF Pfister KK, Wagner MC, Bloom GS, and Brady ST. 1989. Modification of the Microtubule-binding and ATPase Activities of Kinesin by N-ethylmaleimide (NEM) Suggests a Role for Sulfhydryls in Fast Axonal Transport. BIOCHEMISTRY 28: 9006-9012. PDF Bloom GS, and Brashear TA. 1989. A Novel 58 kD Protein Associates with Microtubules and the Golgi Apparatus. JOURNAL OF BIOLOGICAL CHEMISTRY 264: 1608316092. PDF Wagner MC, Pfister KK, Bloom GS, and Brady ST. 1989. Co-purification of Kinesin Polypeptides with Microtubule-Stimulated Mg-ATPase Activity and Kinetic Analysis of Enzymatic Properties. CELL MOTILITY AND THE CYTOSKELETON 12: 195-215. Hirokawa N, Pfister KK, Yorifuji H, Wagner MC, Brady ST, and Bloom GS. 1989. Submolecular Domains of Bovine Brain Kinesin Identified by Electron Microscopy and Monoclonal Antibody Decoration. CELL 56: 867-878. PDF Cover Picture Pfister KK, Wagner MC, Stenoien DL, Brady ST, and Bloom GS. 1989. Monoclonal Antibodies to Kinesin Heavy and Light Chains Stain Vesicle-like Structures, but not Microtubules in Cultured Cells. JOURNAL OF CELL BIOLOGY 108: 1453-1463. PDF Bloom GS, Wagner MC, Pfister KK, and Brady ST. 1988. Native Structure and Physical Properties of Bovine Brain Kinesin, and Identification of the ATP-Binding Subunit Polypeptide. BIOCHEMISTRY 27: 3409-3416. PDF Luca FC, Bloom GS, and Vallee RB. 1986. A Monoclonal Antibody that Cross-Reacts with Phosphorylated Epitopes on Two Microtubule-Associated Proteins and Two 5 Neurofilament Polypeptides. Proceedings of the National Academy of Sciences, USA 83: 1006-1010. PDF Bloom GS, Luca FC, Collins CA, and Vallee RB. 1985. Use of Multiple Monoclonal Antibodies to Characterize the Major Microtubule-associated Protein in Sea Urchin Eggs. Cell Motility 5: 431-446. Bloom GS, Luca FC, and Vallee RB. 1985. Microtubule-Associated Protein 1B: A Novel, Major Component of the Neuronal Cytoskeleton. Proceedings of the National Academy of Sciences, USA 82: 5404-5408. PDF Bloom GS, Luca FC, and Vallee RB. 1985. Identification of High Molecular Weight Microtubule- Associated Proteins (MAPs) in Anterior Pituitary Tissue and Cells Using Taxol-dependent Purification Combined with MAP-specific Antibodies. Biochemistry 24: 4185-4191. PDF Hirokawa N, Bloom GS, and Vallee RB. 1985. Cytoskeletal Architecture and Immunocytochemical Localization of Microtubule-Associated Proteins in Regions of Axons Associated with Rapid Axonal Transport: The IDPN Intoxicated Axon as a Model System. Journal of Cell Biology 101: 227-239. PDF Bloom GS, Luca FC, and Vallee RB. 1984. Widespread Cellular Distribution of Microtubule-Associated Protein 1A in the Mitotic Spindle and on Interphase Microtubules. Journal of Cell Biology 98: 331-340. PDF Bloom GS, Schoenfeld TA, and Vallee RB. 1984. Widespread Distribution of the Major Polypeptide Component of MAP 1 (Microtubule-Associated Protein 1) in the Nervous System. Journal of Cell Biology 98: 320-330. PDF Vallee RB, and Bloom GS. 1983. Isolation of Sea Urchin Egg Microtubules Using Taxol and Identification of Mitotic Spindle Microtubule-Associated Proteins with Monoclonal Antibodies. Proceedings of the National Academy of Sciences, USA 80: 6259-6263. PDF Bloom GS, and Vallee RB. 1983. Association of Microtubule-Associated Protein 2 (MAP 2) with Microtubules and Intermediate Filaments in Cultured Brain Cells. Journal of Cell Biology 96: 1523-1531. PDF 6 Bloom GS, and Lockwood AH. 1980. Redistribution of Myosin During Morphological Reversion of Chinese Hamster Ovary Cells Induced by Dibutyryl Cyclic AMP. EXPERIMENTAL CELL RESEARCH 129: 31-45. Ricklefs RE, and Bloom GS. 1977. Components of Avian Breeding Productivity. AUK 94: 86-96. PDF 7