DNA and It’s Structure DNA: • _____ is often called the “blueprint of life.” • In simple terms, DNA contains the __________________________ within the cell. Why do we study DNA?: We study DNA for many reasons: • its central ___________________________ • ______________ such as cures for diseases • better _______________ Chromosomes and DNA: • • Our _______ are on our _________________. _____________ are made up of a _________ called DNA. Discovery of DNA Structure: • 1944: _____________ and his team determine that genes are composed of _______ • 1951: _____________ and Robert Corey determine that the structure of a class of _________ is a _______ • 1952: ______________ studies the _____molecule using X-ray _____________ • 1953: James ________ and Francis ________ develop the ________________ model of DNA The Shape of the Molecule: • • • DNA is a very long __________. The basic shape is like a _____________ or zipper. This is called a ____________. The Double Helix Molecule: • The _____ double helix has two _________ twisted together. One Strand of DNA: • The ____________ of the molecule is alternating ____________ and _____________ sugars • The rungs are ______________ bases. Nucleotides: One ___________ together with its _____________ and base make a ___________. One Strand of DNA: • One strand of DNA is ________________________. • One strand of DNA __________________________. Four nitrogenous bases: -___________ -___________ -_____________ -_____________ Two Kinds of Bases in DNA: • • _____________are single ring bases. _____________are double ring bases. Thymine and Cytosine are pyrimidines: • ___________ and __________ each have _____ ring of carbon and nitrogen atoms. Adenine and Guanine are purines: • __________ and ___________each have _____ rings of carbon and nitrogen atoms. Two Stranded DNA: • Remember, ____ has _____ strands that fit together something like a • _________. The ______ are the nitrogenous bases but why do they stick together? Hydrogen Bonds: • The ______ attract each other because of _________________. • Hydrogen bonds are ______ but there are millions and millions of them in a • • _________________________. When making _______________, cytosine always pairs up with guanine __________ always pairs up with ___________ Chargraff’s Rule: •_________ and ________ always join together •_________ and ________ always join together DNA by the Numbers: • Each cell has about ______________. • The average human has _______________. • The average human has enough DNA to go from the earth to the sun ___________________. • DNA has a diameter of only ______________. DNA Replication • • • • • • • When?______________________________________ Why? _______________________________________ Enzymes _____________the helix DNA ________________adds new bases to each original strand Matches _______AND _________ DNA replication is “______________________”- one new strand, one old strand WE CREATE AN _____________________OF THE __________________