North Garland High School
Career & Technology Division
Pathophysiology - HPRS 2201-5210
Syllabus – Fall 2011 - Spring 2012
Instructor: Dr. Kevin Hunter, D.A.A.P.M., F.I.A.M.A.
Course Description:
This course presents the basic principles of pathophysiology emphasizing clinical applications. Topics include
principles of homeostasis related to body systems.
Mission
An increasing number of students in health sciences at North Garland High School require an introduction to
human papathology. Currently, the only available course in human pathology is HPRS 2201-5210, which is
designed primarily for MST and Honors students. This course is dual credit and taught in conjunction with El
Centro, a Dallas County Community College. This allows the student a chance to receive college credits while still in
high school.
Overview
This subject provides a comprehensive overview of human pathology with emphasis on mechanisms of disease.
Topics include (1) General Mechanisms of Disease (Inflammation, Infection, Immune Injury, Host Response to
Foreign Materials, Genetic Disorders and Neoplasia), (2) Pathology of Lipids, Enzymes and Hematopoietics, (3)
Pathology of Major Organ Systems. The objectives of this course are achieved by a set of integrated lectures and
laboratories, as well as a student-driven chapter projects leading to formal presentations on medical issues in
human pathology.
Prerequisites
A basic understanding of Biology /cellular biology and Human Anatomy/physiology is required to study human
pathology and mechanisms of disease.
Textbook
Pathology: For The Health Professions, 3rd edition, by Damjanov, Elsivier Saunders, 2006
This softcover textbook has excellent course summaries and is generously illustrated. Key points are clearly
outlined. Each chapter has specific questions.
Required reading for other lectures and topics will be in the form of lecture notes, review articles, or original
articles. These will be handed out or presented in class.
Learning Outcomes:
The student will apply knowledge of biological and social sciences to define and explore elements of
pathophysiology and use critical thinking to examine alterations in normal body function that lead to disease and
discomfort.
Teaching/Learning Activities:
Lecture
Group Discussion
Audio-visual Aids
Critical Thinking Exercises
Course Objectives:
1. Discuss normal physiologic functions, which maintain dynamic equilibrium of the human body. (Provider of Care)
2. Discuss selected concepts of disordered function or form which leads to health disruptions and discomfort in the
human organism’s relationship with the environment. (Provider of Care)
3. Discuss concepts of positive and negative feedback as related to human functioning. (Provider of Care)
4. Describe compensation within the human body. (Provider of Care)
5. Describe pathophysiology, tests, and treatments amenable to proper care for common types of cancer.
(Provider of Care)
6. Describe the causes, pathophysiology, diagnostic tests, and treatments amenable to proper care for several
common infectious diseases. (Provider of Care)
7. Describe the pathophysiology, signs and symptoms, diagnostic tests, and treatments amenable to proper care
for various immune disorders. (Provider of Care)
8. Describe the pathophysiology, signs and symptoms, diagnostic tests, and treatments amenable to proper care
for several endocrine disorders. (Provider of Care)
9. Describe the pathophysiology, diagnostic tests, and treatments amenable to proper care or several respiratory
diseases. (Provider of Care)
10. Describe the causes, pathophysiology, diagnostic tests, and treatments amenable to proper care for several
common cardiovascular disorders. (Provider of Care)
11. Describe the causes, pathophysiology, diagnostic tests, and treatments amenable to proper care for several
common neurologic disorders. (Provider of Care)
12. Describe the pathophysiology, signs and symptoms, diagnostic tests, and treatments amenable to proper care
for common blood disorders. (Provider of Care)
13. Describe the pathophysiology, signs and symptoms, diagnostic tests, and treatments amenable to proper care
for common digestive disorders. (Provider of Care)
14. Describe the pathophysiology, signs and symptoms, diagnostic tests, and treatments amenable to proper care
for several common renal system disorders. (Provider of Care)
15. Describe the pathophysiology, diagnostic tests, and treatments amenable to proper care for certain
musculoskeletal disorders. (Provider of Care)
Power points with mini cases
The mini cases are small case-studies you will design to help demonstrate how well you integrated the materials
covered in class and in your chapter studies. You are expected to design a power point with the mini cases and to
defend your opinion about your case study, you should have spent enough time on the case to be able to
moderate the class discussions about it. The assignment will be distributed approximately 2 class sessions before
each scheduled presentation period.
Grading
Your final grade in Pathophysiology - HPRS 2201-5210 will be determined based on the following criteria:
Chapter exams: Twenty or more multiple-choice or short-answer questions. The questions will draw on the
information presented in lectures, as well as the reading assignments. Up to 40% of the questions on the Final
exam may be based on questions from the chapter tests.
Final exam: Fifty multiple-choice, matching or short-answer questions. Questions will draw on the information
presented in lectures, as well as the reading assignments. The final exam covers the material presented in the
entire course.
Chapter Questions assigned as homework: Ten homework assignments. The homework assignments are an
essential part of this course.
Chapter power point presentation: Each student is required to conduct a literature-based study on a medical,
socioeconomic, or technological issue related to pathology or diagnostic medicine. Each student will produce a
power point (minimum of 6 slides) and present his or her findings before the class. Topics will be broad and your
mini case should captivate the class.
A few examples of topics include:
o Ulcerative colitis
o Barrett's esophagus
o Sickle cell anemia
o Emphysema
o Tetralogy of Fallot
Class participation is required and viewed as an important part of this class. You will develop your critical thinking
skills while trying to solve different case scenarios. This is a fun and enlightening way to learn!