ST. DAVID’S HEALTHCARE SYSTEM NEONATAL INTENSIVE CARE Study Guide Information The medication test emphasizes essential, basic knowledge required for safe practice. It is a multiple-choice format. The quiz evaluates: 1. dosage calculations 2. principles of drug administration and nursing implications 3. effects of commonly used drugs. An 80% is required to pass. In the event that a passing score is not achieved, a second exam will be given. Please refer to the study guide for review. A Neofax will be provided for the medication exam. 1 List the drug classification of each of the following and identify some of the most important nursing implication(s) related to the drug. 1. Acyclovir (Zovirax) 2. Alprostadil (PGE1) (Prostin VR Pediatric) 3. Ampicillin sodium 4. Beractant (Survanta) 5. Caffeine citrate 6. Calfactant (Infasurf) 7. Clindamycin sodium (Cleocin) 8. Dexamethasone (Decadron) 9. Dobutamine hydrochloride (Dobutrex) 10. Dopamine hydrochloride (Intropin) 11. Erythropoietin [EPO] (Epogen) 12. Fentanyl sulfate (Sublimaze) 13. Furosemide (Lasix) 14. Gentamicin (Garamycin) 15. Indomethacin (Indocin) 16. Metochlopramide (Reglan) 17. Palivizumab (Synagis) 18. Phenobarbital (Luminol) 19. Phenytoin (Dilantin) 20. Ranitidine (Zantac) 21. Theophylline 22. Tromethamine (THAM) 23. Vancomycin (Vancocin) 2 RIGHT MEDICATION RIGHT PATIENT RIGHT TIME RIGHT ROUTE RIGHT AMOUNT NOTES: _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________ 3 Identify major nursing implications when administering medications in the following ways: A. Subcutaneous (sub-q): B. Intramuscular (IM): C. Into the eye: D. Rectal (suppositories): E. Into the ear: G. Reconstitution (diluting): H. Central line VS. Peripheral line: Universal Precautions should be applied to any situation where the nurse may come into contact with secretions or fluids from a patient. The assessment for, and wearing of, personal protective equipment IS part of professional nursing behavior. ORAL Medications: This is the easiest, safest and therefore, most desirable route of medication administration. The nurse must guard the patient against aspiration. Correctly positioning the patient is an important function of the nurse. Transferring the liquid from bottle to medicine cup should be done without touching the medication. Liquid medications should be poured into a medication cup held at eye level to ascertain that the meniscus is at the appropriate level on the scale. Liquid volumes less than l0cc should be drawn up into a syringe. OPTHALMIC Medications: If administering an eye ointment, run a thin stream along inside edge of lower eyelid. Do the same for the upper lid margin. After instillation of either drips or ointment the client should close their eyes. OTIC Medications: Bring fluid to room temperature prior to instillation. Ear structures are sensitive to temperature extremes. Help patient to side lying position with affected ear up. Straighten ear canal by pulling the pinna up and out for an adult and down and back for children. Pulling the pinna in the proper direction ensures that the medication will be delivered to the appropriate inner structures. 4 RECTAL Medications: Apply gloves. Remove suppository from wrapper. Lubricate tip of the suppository before insertion. Insert suppository PAST external sphincter at least 4 inches in an adult and 1 inches in a child or infant. PARENTERAL Medications: Parenteral administration of medications is given by injection into body tissues. There are four common routes: Subcutaneous (SQ); Intradermal (ID); Intramuscular (1M); and Intravenous (IV). _Subcutaneous: medication is placed into the loose connective tissue under the dermis. If circulatory status is normal then drug absorption from this site is complete. The patient's body weight will indicate the depth of the SQ layer. Only water-soluble medications should be given by this route. Intradermal: is typically used for skin testing. Intramuscular: the greater the vascularity of muscle tissue allows for speedier absorption of medication. In this procedure, weight is a determining factor in choosing the length of the needle to be used. IV Administration: Typically, three different methods are used: m; an admixture with large volumes of IV fluids, as an injection or bolus of a small amount of medication usually through an existing IV line or heparin or sa1ine lock, or as a piggyback infusion. The tissue circulation is the most important factor affecting the rate of drug absorption from the parenteral route. Advantages fast acting drugs may be delivered quickly constant therapeutic levels of a drug may be maintained some medications which are highly irritating to tissues would not be administered comfortably either by the IM or SQ routes Weight 1 ounce 1000 mcg 1000 mg 16 ounces 1 kg 30 grams 1 mg 1g 1 lb 2.2 lbs Volume 1 mL 0.001 liter (l) 1000 mL 1 liter (1) 1000 liters 1 kiloliter (kl) . 16 fluid ounces 60 drops 1 minim 4 teaspoon (tsp) 8 ounces 1 pint (pt) 1 teaspoon (tsp) 1 drop (gtt) 1 tablespoon (tbsp) 1 glassful 5 1000 kiloone thousand 100 hectoone hundred 10 decaten 1 0.1 meter liter gram decione tenth 0.01 centione hundredth 0.001 millione thousandth 0.000001 microone millionth Practice Problems: 1. 1000 mL = ______________ liter(s) 6. 10 g = _______________ kg 2. 60 mL = _______________ liter(s) 7. 500 L = ______________ mL 3. 25 mm = _______________ m 8. 6 g = ________________ mg 4. 250 mg = ______________ g 9. 250 cc = _____________ mL 5. 20000 g = ________________ kg 10. 500 mg = ______________g Define each: ABBREV TRANSLATION ABBREV TRANSLATION mEq tid hs SL pc OD ac 1M gtt q4h ___ s OS LOC Gm SQ mg NPO STAT ___ c 6 Medication Calculation: (ordered dose x total volume) = dose available dose Dopamine drip calculations: Weight (kg) x 6 x desired dose (mck/kg/min) = mg of drug/100 ml Desired IV fluid rate (ml/hr) PRACTICE PROBLEMS: 1. Dopamine is ordered: 5mcg.kg/min. The infant weighs 3 kg. Infusion rate is ordered at 3 ml/hr. How many mg of Dopamine do you add to 100 ml for this drip? 2. Oral solution of Caffeine is supplied as 10mg/ml. You need to give 7.5 mg P.O. How many ml's do you give? 3. Gentamicin is supplied as 20 mg/2ml. Dosage for Gentamicin is 2.5 mg/kg/dose. Your infant weighs 3415 gm. Order reads: 8.5 mg Gentamicin I.V. q 12 hours. Questions: How many kilograms is this infant weight? Is this an appropriate dose for this infant? How many ml do you administer? 4. Pediatric oral digoxin is supplied as 50 mcg/ml. You need to administer 44 mcg, How many ml's do you give? 5. You have a vial of Ampicillin that contains 250 mg per 5 ml. Your order reads: 325 mg Ampicillin IV q 8 hours. How many ml's do you draw up into the syringe? 7 6. Phenytoin is supplied in a concentration of 50 mg/ml. Your ordered reads 36mg Phenytoin IV now. Volume: __________ Sodium bicarbonate is supplied in a 4.2% concentration which is 0.5 mEq/ml. MD order reads: “3 mEq NaHCO3 IV now. How many ml will you give? 7. 8. Baby Jim weighs 1200 gm and is 28 weeks in gestation. What would the correct dose of Acyclovir be using the following information. Dose: 20 mg/kg Interval for neonates: 8 hours for infants 34 weeks and over; 12 hours for 34 weeks and under Vial contains 500 mg diluted in 10 ml of normal saline. This is further diluted by adding 1 ml to 9 ml of normal saline. Infusion solution should be < 7 mg/ml Dose: __________ Interval: Every __________ hours Volume: __________ ml/dose IV over __________ hour(s) Answer Sheet 1. 2. 3. 4. 5. 1 liter 0.06 liter 0.025 m 0.25 g 20 kg 6. 0.01 kg 7. 500,000 ml 8. 6000 mg 9. 250 ml 10. 0.5 g 8 ABBR mEq tid hs pc ac gtt TRANSLATION milliequivalent three times a day hour of sleep after meals before meals drop ABBR TRANSLATION SL OD IM sublingual right eye intramuscular without left eye q4h every 4 hours ___ s OS LOC level of consciousness/laxative of choice gram nothing by mouth SQ mg subcutaneously milligram ___ c with Gm NPO STAT immediately 1. 3 x 6 x 5 3 = 90 3 = 30 mg Dopamine to be added to 100 ml 2. 0.75 ml 3. 3.4 kg – Yes, it is correct – 0.85 ml 4. 0.88 ml 5. 6.5 ml 6. 0.72 ml 7. 6 ml 8. Dose: 24 mg, Every 12 hours, 4.8 ml/dose IV over 1 hour 9