Chapter 7 The Nervous System Chapter Objectives Upon completion of this chapter the participant will be able to: 1. 2. 3. 4. 5. 6. 7. 8. 9. Name the divisions of the nervous system. Describe the major functions of the nervous system. Discuss the function of the nerve cell. Label a diagram of the nerve cell and the brain. Discuss the function of the various divisions of the brain. List the protective coverings of the brain. Discuss the function of the spinal cord. Analyze, define, spell and pronounce the common terms associated with the nervous system. Successfully complete the exercises at the end of the chapter. The nervous system allows the body to adjust to the requirements of both the inside and outside of our bodies. As soon as a change in either environment is detected the brain is notified and it decides what would be the appropriate response and then brings about that change. This may sound simple but in actual fact it is a very complex process. The nervous system is more complex than the most sophisticated computer. Anatomy and Physiology of the Nervous System Nerves The nervous system is made up of nervous tissue that consists of bundles of fibers that carry impulses throughout the body. The root word for nerve is neur/i or neur/o. There are two different types of nerve cells that are found in the nervous system: neurons: carry nerve impulses back and forth through the body neuroglia: found between the neurons and act as a protection for the neuron. Neuron Neurons are made up of three main parts, each with a very distinct role. These parts are: Cell Body: Contains all the structures that maintain the cell. Dendrites: Root like structures that receive impulses and conduct them toward the cell body. The root for dendrites is dendr/o. Axon: Extends away from the cell body and conducts the impulse away from the nerve body. Some axons are protected by a white fatty substance called myelin. The root for axon is axo/. Revised August 2003 -69- Dendrite Nucleus Cell body Axon Myelin bead Myelin sheath Direction of Impulse Flow The nervous system is divided into three major structures: Central Nervous System: Consists of the brain and spinal cord which is protected by fluid and a series of membranes. Protection from trauma in the environment is obtained by the skull and the bones of the vertebrae. The brain is the information processing area and the spinal cord is the body’s information super-highway. Peripheral Nervous System: Consists of cranial nerves which extend from the brain, and spinal nerves which come from the spinal cord. Autonomic Nervous System: Consists of ganglia on either side of the spinal cord. Nerves of the autonomic nervous system control involuntary actions of the body which we are not able to control; e.g. heart rate, breathing. Impulse Transmission In order for the nervous system to carry on its many functions there must be transmission of messages back and forth from one part of the body to another. The nerves allow for this and the process occurs smoothly with the help of neurotransmitters. Neurotransmitters are chemical substances that make it possible for the impulse to jump from one nerve cell to another. We know of at least 40 Revised August 2003 -70- neurotransmitters in the body, each with a very specific function. The space between the nerve cells is referred to as the synapse. An impulse will travel down a neuron to a synapse and then a neurotransmitter is released that allows the impulse to jump to the next neuron. Central Nervous System The Central Nervous System is made up of the brain and spinal cord. The root for brain is either encephal/o or cerebr/o. The root for spine is spin/o and for spinal cord is myel/o. The brain which is encased in the skull is made up of the following parts: Cerebrum: The largest part of the brain which receives impulses from all areas of the body. It is the area of the brain that holds our intellectual ability. The cerebrum is divided into two hemispheres by a gap that extends down the middle of the tissue. These two areas are connected by bundles of nerves that allow the two hemispheres to function together. If for some reason the hemispheres become spilt each can function independently but there isn’t the integration of functions that normally occurs. The outer layer of the cerebrum is a thin gray layer called the cerebral cortex. The cerebrum is involved in sensory and motor function as well as thought, judgment and our perception. Each of the two hemispheres of the brain is divided into lobes: frontal lobe, parietal lobe, temporal lobe and occipital lobe. Thalamus: The thalamus acts as a relay station for impulses coming into the brain. This area is responsible for detection of touch, temperature and pain. The root for thalamus is thalam/o. Hypothalamus: Located below the thalamus. It helps regulate the functions of the autonomic nervous system. It helps regulate appetite, thirst, temperature, sleep cycles and the amount of water retained by the body. Brain Stem: This area is sometimes referred to as the “animal brain” because it is the site of the basic life functions of breathing, heart beat, blood pressure, ability to see and ability to hear. It is also responsible for the responses of coughing, sneezing and swallowing. Cerebellum: Lies just below the occipital lobe of the cerebrum. It is responsible for balance, coordination and equilibrium. Root for cerebellum is cerebell/o. Revised August 2003 -71- Parietal Lobe Skull Dura Mater Arachnoid Mater Frontal Lobe Pia Mater Temporal Lobe Brain Stem Hypothalamus s Thalamus Cerebellum Spinal Cord The human brain weights a mere three pounds and looks like a gray, unshelled walnut, yet it is the most complex structure in our world and the body's most vital organ. It encases some 100 billion or more nerve cells, and is capable of sending signals to thousands of other cells at speeds of more than 200 miles an hour. It defines who we are, yet is influenced by what we do. It holds the secrets to conditions that have perplexed mankind for centuries. Protection for the Brain Skull: The bones that make up our skull protect the brain tissue from external trauma. The root for skull is crani/o. Meninges: A series of three membranes that cover the brain tissue. The root for meninges is mening/o and meningi/o. The three membranes are the dura mater, arachnoid mater and pia mater. In the space below the arachnoid mater and above the pia mater (subarachnoid) there is a fluid called the cerebrospinal fluid that acts as a cushion to absorb trauma during a head injury. This fluid absorbs a great deal of the impact so the brain tissue doesn’t become bruised. Revised August 2003 -72- Blood-Brain Barrier: A mechanism that prevents dangerous or toxic substances from leaving the blood stream and moving into brain tissue. It does allow necessary substances like oxygen and nutrition to pass through, into the brain. Spinal Cord The spinal cord extends from the base of the brain down the back in a canal referred to as the spinal canal. The cord consists of nerves that are encased in 31 vertebrae for protection. The spinal cord branches into 31 pairs of spinal nerves that extend from the cord to the limbs and lower parts of the body. The root for spinal cord is myel/o. Like the brain it is protected by the three layers of meninges and the cerebrospinal fluid. Peripheral Nervous System Revised August 2003 -73- The peripheral nervous system consists of the cranial nerves which extend from the brain and the spinal nerves which extend from the spinal cord. We have 12 pairs of cranial nerves and they are named for the area they affect or the function they are responsible for such areas of the body as the: eyes, face, throat, mouth, tongue, thorax. There are 31 pairs of spinal nerves, which are generally named for the artery they accompany or the body part they affect; e.g. the femoral nerve affects the muscles along the femur. Autonomic Nervous System This aspect of the nervous system is divided into two parts; the parasympathetic and sympathetic. Each division acts as a balancer of the activities of the other. This allows a state of homeostasis to exist in the body. The sympathetic system is concerned with preparing the body for emergency/stressful situations. To prepare you to react quickly in these situations, your breathing rate, heart rate and blood circulation to the muscles is greatly increased. It also decreases the rate of your digestion as this is not a necessity in an emergency situation. The parasympathetic system, in contrast, returns your body to a state of calm after a stressful situation has passed. It also maintains normal body functions during ordinary daily circumstances. Diagnostic Procedures The most common procedures used to diagnose problems of the nervous system involve the use of sound and dyes to create graphic pictures. The advances in technology have allowed for two very specific procedures to be developed: Magnetic Resonance Imaging (MRI) uses a combination of radio waves and a strong magnetic field to create images in any part of the body. This procedure is used in diagnosing brain problems, as well as other problems in the body. The second procedure is the Computerized Axial Tomography (CAT Scan). During this procedure an X-Ray beam rotates around the patient and details the structure to be examined at various depths. The information is then computerized and converted to a picture of that part of the body. Pathology of Diseases of the Nervous System Injuries to the nervous system may be the result of one or a combination of the following: Inflammation Trauma Decrease in blood circulation to the tissue resulting in death of tissue Congenital injuries Revised August 2003 -74- Word Parts for the Nervous System Roots ax/o cephal/o cerebell/o cerebr/o, encephal/o cortic/o dendr/o dur/o encephal/o, cerebr/o gangli/o, ganglion/o hydr/o medull/o mening/o, meningi/o myel/o narc/o neur/o noct/i radicul/o somn/i, somn/o spin/o synaps/o, synapt/o thalam/o ventricul/o axon head cerebellum brain cortex, outer covering dendrite dura mater brain ganglion water medulla, inner section meninges, membrane spinal cord, bone marrow numbness nerve night nerve root sleep spine synapse thalamus ventricles Suffixes -algia, -dynia -cele -ectomy -esthesia -graphy -kinesia, -kinesis -oma -phasia -plegia -taxia pain hernia, protrusion removal sensation, feeling process of recording, producing images movement, motion tumor speech paralysis, loss of motor function order Prefixes deechopachysub- Revised August 2003 lack of, removal sound thick below -75- Term Analysis and Definition Word Part Term Term Analysis cerebell/o cerebellar cerebell = cerebellum -ar = pertaining to Pertaining to the cerebellum cerebr/o, encephal/o cerebral cerebr = brain -al = pertaining to Pertaining to the brain cerebrospinal spin = spine Pertaining to the brain and spine cerebrovascular vascul = vessel -ar = pertaining to Definition Pertaining to the brain and blood vessels encephalitis encephal = brain -itis = inflammation Inflammation of the brain encephalomalacia -malacia = softening Softening of the brain cortical cortic = cortex, outer covering -al= pertaining to Pertaining to the cortex corticospinal spin = spine Pertaining to the cortex and spine epidural epi = on, upon, above dur = dura mater -al = pertaining to Pertaining to above the dura mater subdural sub = below, under Pertaining to under the dura mater hydr/o hydrocephalus hydr = water cephal = head -us = pertaining to Pertaining to an accumulation of fluid in the brain mening/o, meningi/o meningitis mening = meninges, -itis = inflammation Inflammation of the meninges meningoencephalitis encephal = brain Inflammation of the meninges and the brain myelogram myel = spinal cord, bone marrow -gram = record Record of the spinal cord cortic/o dur/o myel/o Revised August 2003 -76- Word Part Term Term Analysis Definition poliomyelitis -itis = inflammation polio= gray Inflammation of the gray matter of the spinal cord myoneural my = muscle -al = pertaining to neur = nerve Pertaining to the muscle and nerve neuralgia -algia = pain Nerve pain neurology -logy = study of Study of the nervous system neurologist -logist = one who specializes in the study of A specialist in the diagnosis and treatment of nervous system diseases neurolysis -lysis = destruction, breakdown Nerve destruction radicul/o myeloradiculitis myel = spinal cord radicul = nerve root -itis = inflammation Inflammation of the spinal cord and nerve roots. spin/o spinal spin = spinal -al = pertaining to Pertaining to the spine thalam/o thalamocortical thalam = thalamus cortic = cortex -al = pertaining to Pertaining to the thalamus and cerebral cortex ventricul/o ventriculostomy ventric = ventricles neur/o, neur/i -stomy = permanent new opening Creating a permanentnew opening into the ventricles -algia cephalalgia cephal = head -algia = pain A pain in the head (Headache) -cele encephalocele encephal = brain -cele = hernia Hernia of the brain meningocele mening = meninges Hernia of the meninges myelomeningocele myel = spinal cord Hernia of the spinal cord and meninges lobectomy lobe = lobe -ectomy = surgical excision Surgical excision of a lobe of the brain -ectomy Revised August 2003 -77- Word Part -esthesia -graphy -kinesia, -kinesis -oma -otomy Term Term Analysis Definition craniectomy crani = skull Surgical removal of a part of the skull anesthesia an = no, not -esthesia = sensation No sensation hypoesthesia hypo = below, under Decreased sensation hyperesthesia hyper- excessive, above Increased sensation paresthesia para = abnormal Abnormal sensation cerebral angiography cereb = brain -al = pertaining to angi = vessel -graphy = process of recording Graphic X-Ray image of the vessels in the brain.. computerized axial tomography tom/o = to cut X-Ray beam creates a picture of various depths of the brain electroencephalo -graphy electr= electric Process of recording the electric impulses of the brain myelography myel= spinal cord hyperkinesis hyper = above, excessive -kinesis = movement Excessive movement, hyperactivity dyskinesia dys = difficult, bad -kinesia = movement Difficult movement meningioma mening = meninges Tumor of the meninges myeloma myel = spinal cord Tumor of the spinal cord neurotomy neur = nerve -tomy = Surgical incision Surgical incision into a nerve Revised August 2003 -78- X-Ray image of the spinal cord Word Part -pathy -phasia -plegia Term Term Analysis Definition craniotomy crani = skull Creation of an opening into the skull encephalopathy encephal = brain -pathy = disease Disease of the brain neuropathy neur = nerve Disease of the nerve aphasia a = no, not phasia = speech No speech dysphasia dys = difficult, bad Difficult speech hemiplegia hemi = half -plegia = paralysis Paralysis of either (half) the right side or left side of the body monoplegia mono = one Paralysis of one extremity paraplegia para = beside, near Paralysis of the lower part of the body and legs Paralysis of all four limbs quadriplegia quad = four -taxia ataxia a = no, not -taxia = order No muscular coordination de- demylination de- = lack of, removal mylin = myelin sheath -ion = process Loss of the myelin sheath. Vocabulary Words: Alzheimer’s disease A severe form of senile dementia that may be due to some defect in the neurotransmitter system. There is cortical destruction that causes variable degrees of confusion, memory loss and other cognitive defects. Anorexia nervosa A complex psychological disorder in which the individual refuses to eat or has an aberrant eating pattern coma An unconscious state or stupor from which the patient cannot be aroused Revised August 2003 -79- epilepsy A disorder of cerebral function resulting from abnormal electrical activity or malfunctioning of the chemical substances of the brain herpes zoster shingles, an acute viral disease characterized by painful vesicular eruptions along the segment of the spinal or cranial nerves paresis A slight, partial, or incomplete paralysis Parkinson disease A chronic disease of the nervous system. It is characterized by a loss of equilibrium and by salivation, frustration, nausea, dryness of the mouth, and muscular tremors, syncope, and fainting Abbreviations: ALS amyotrophic lateral sclerosis ANS autonomic nervous system CNS central nervous system CSF cerebrospinal fluid CT computerized tomography CVA cerebrovascular accident LP lumbar puncture MS multiple sclerosis PNS peripheral nervous system TIA transient ischemic attack Revised August 2003 -80-