History of Microbiology I. What are Microorganisms? A. B. C. D. _________________: living organisms (or virus) too small to be seen with the unaided eye Includes: ____________________________________________________________ _____________________________ cause illnesses in humans Many Benefits: 1. ______________________ (dead organic, waste material, some industrial waste) 2. Phytoplankton – fresh water and oceans - _____________________________________________ 3. _______________________ – change nitrogen to usable form (nitrogen fixation) 4. Aid in digestive tract , some needed for vitamin synthesis 5. ______________________ – pickles, vinegar, alcohol, bread, yogurt 6. Synthesize ________________________ 7. Major tools in _____________________________ (interferon and growth hormones) II. History A. 1665 _________________________________ 1. simple microscope 2. sliced cork 3. “__________________” – small internal structures B. 1673-1723 1. 2. 3. 4. 5. (English) _________________________________ (Dutch merchant) _____________________________________________________ “animalcules” studied _______________________________________________ bacteria & protozoa did not pass his knowledge on People Becoming Interested in the Origin of Living Things _______________________________________: · hotly debated · __________________________________________________________________________ C. 1668 __________________________________ (Italian physician) 1. thought he proved Biogenesis (______________________________ __________________________________________________________) 2. Controlled experiment Control D. 1745 Variable 1 Variable 2 John Needham (English scientist) 1. thought he proved abiogenesis (spontaneous generation) 2. 3. see experiment with Spallanazni E. 1765 Lazzaro Spallanzani (Italian Scientist) 1. _________________________________________________________ (Needham)