Name:____________________________________________________Date:__________________Period:__________ HIV and AIDS - Day 12 Objective: Students will be able to explain what a retrovirus is and how it works. QUESTION: What is the difference between HIV and AIDS? Answers will vary. Research HIV and AIDS AIDS stands for acquired immunodeficiency syndrome, a disease that makes it difficult for the body to fight off infectious diseases. The human immunodeficiency virus known as HIV causes AIDS by infecting and damaging part of the body's defenses against infection — its lymphocytes, which are a type of white blood cell in the body's immune (infection-fighting) system that is supposed to fight off invading germs. HIV can be transmitted through direct contact with the blood or body fluid of someone who is infected with the virus. That contact usually comes from sharing needles or by having unprotected sex with an infected person. An infant could get HIV from a mother who is infected. HIV and AIDS can be treated, there are no vaccines or cures for them. What HIV Does to the Body The virus attacks specific lymphocytes called T helper cells (also known as T-cells), takes them over, and multiplies. This destroys more T-cells, which damages the body's ability to fight off invading germs and disease. When the number of T-cells falls to a very low level, people with HIV become more susceptible to other infections and they may get certain types of cancer that a healthy body would normally be able to fight off. This weakened immunity (or immune deficiency) is known as AIDS and can result in severe life-threatening infections, some forms of cancer, and the deterioration of the nervous system. Although AIDS is always the result of an HIV infection, not everyone with HIV has AIDS. In fact, adults who become infected with HIV may appear healthy for years before they get sick with AIDS. What does AIDS stand for? Acquired Immunodeficiency Syndrome What does AIDS do to the body? Infects and damages the lymphocytes or white blood cells of the body What would happen if the AIDS killed off all of lymphocytes? You would not be able to defend against other diseases How do you get HIV? Sharing needles or unprotected sex What, specifically, does this disease do to the body? The virus attacks the T cells, takes them over in order to make more viruses that attack more T cells If HIV/AIDS does not kill you, then what does? How does that work? Without having any immune cells you would not be able to stop other infections from attacking you and those other diseases would kill the virus. Question: What Is the difference between HIV and AIDS? What does HIV stand for? Human Immunodeficiency Virus Answer: The quick answer is that the difference between HIV and AIDS1 is that HIV is a virus and AIDS is a definition. What is the difference between someone with early stages of HIV verse someone with later stages of HIV? What does HIV stand for? HIV stands for the "human immunodeficiency virus." In other words, it is a virus that infects human being and leads to problems with their immune system. The immune system2 is the body's system for fighting disease. Someone in early stages would have many white blood cells to protect them. Someone in late stage would have little or no white blood cells to protect them. AIDS and HIV Understanding what it means to be HIV positive is relatively simple -- either you are infected with the virus or you aren't -- but how do you understand AIDS? AIDS, which stands for "Acquired Immune Deficiency Syndrome" is a way of describing a whole group of symptoms and diseases associated with the damage HIV does to the immune system. As an HIV infection progresses, there is ongoing damage to immune defense cells and the body becomes increasingly less able to fight off infection. This means that individuals with advanced HIV disease are susceptible to infections that don't show up in people with healthy immune systems. They are called opportunistic infections because they take advantage of the weakened ability of an HIV positive individual to fight off disease. The difference between AIDS and HIV is that a person is said to have AIDS, as opposed to simply being HIV positive, when either the numbers of specific types of cells in their immune system3 drop below a certain level or when they develop one of a specific group of opportunistic infections4. What is an opportunistic disease? Any disease that attacks the body when the immune system is weakened What is the difference between HIV and AIDS? HIV is the virus that attacks and destroys the Tcells. AIDS is the point when so many white blood cells are destroyed that the body could become infected with opportunistic diseases. Conclusion: Using the knowledge you gained today. Answer the question: What is the difference between HIV and AIDS? Answers will vary, but should include: HIV with definition AIDS with definition T-Cells White Blood Cells Immune Deficiency Ask a partner to read your Partner's Name: Printed paragraph. Have them score it 1-5. 5 being the best Teacher Score Score