Summary of Medications: (Full descriptive drug cards attached) Atorvastatin (Lipitor) PO 10mg tab (takes two tabs) Class: Antihyperlipidemia (HMG-COA Reductase Inhibitors) Action; HMG-CoA reductase is a rate-controlling enzyme of cholesterol syntheses. (Mosby, pg 821) If this enzyme is blocked, serum cholesterol and LDL levels decrease, because more LDL’s are absorbed by the cells for processing into cholesterol.(Karch, pg 638) In return HDL levels increase slightly with this alteration in fat metabolism. These HMG-COA Reductase Inhibitors block HMG-CoA reductase from completing the synthesis of cholesterol. (Karch, pg 638) Reason Patient is Taking: To decrease his cholesterol levels, his cholesterol is directly affected by his(prior) diagnosis of Coronary Artery Disease. A nutritional consult was documented on 4/6/04. Advisement by nutrition was to be put on a low cholesterol diet. Patient verbalized understanding and was receptive to the consult. He was given information with sample menus. Isosorbide Mononitrate PO 30 mg 1 tab qd Class: Antianginal Action: Produces vasodilation, decreases left ventricular end-diastolic pressure and left ventricular end-diastolic volume(preload) Increases coronary blood flow by dilating coronary arteries and improving collateral flow to ischemic regions. (Davis pg. 257) Nitrates are drugs that act directly on smooth muscle to cause relaxation by dilating veins, arteries and capillaries, allowing increased blood flow through these vessels.(Karch pg 623) CAD causes a stiffening and lack of responsiveness in the coronary arteries, these drugs increase blood flow through healthy coronary arteries. The main effect is a drop in blood pressure, decreases preload, and decreases afterload.(Karch pg 623) Reason Patient is taking: My patient has a prior diagnosis of Coronary Artery Disease, this medication is helping treat conditions related to this disease process. He also has a history of hypertension, however on my shift his blood pressure measured 0800 140/50, on the day prior a 1800 reading was documented at 130/40 and upon admission his blood pressure was 140/60. His apical pulse at 0800 on the day of my shift 4/7/04 was 72 and regular. Patient teaching may include education regarding monitoring his blood pressure at home. Protonix PO 40 mg 1 tab qd Class: Anti-Ulcer Proton Pump Inhibitor Action: Suppresses gastric acid secretion by specifically inhibiting the H+, K+, -ATPase enzyme system on the secretory surface of the gastric parietal cells. This action blocks the final step of acid production, lowering the acid levels in the stomach.(Karch pg 780) Reason my patient is taking; It was not documented in the chart of a prior ulcer, however, S.N. expressed that he frequently suffers from stomach upset from all of the medications he is on. During my shift on 4/7/04 S.N. did not have any stomach upset and when asked to rate his stomach pain he stated it was a zero. Patient teaching would include limiting food intake to foods that are not irritating to the GI tract. Also discussing prior coping mechanisms with regard to pain would assist S.N. in dealing with episodes he might have in the future. Phytonadione Mephyton PO 5 mg 1 Tab qd Class: Fat Soluble Vitamins Action: This medication is a form of Vitamin K and is used to reverse the effects of warfarin. Vitamin K is responsible for promoting the liver synthesis of several clotting factors. If an increased level of Vitamin K is provided clotting time can be brought back within a normal range. Reason my patient is taking: S.N. platelet count was 246 on 4/5/04, however he does have Cellulitis on his left lower extremity that is not healing with prior treatment. In the chart there was no documentation of clotting problems, this was a home medication that he has been taking. Prednisone PO (Only on even days) 5mg 1 tab qod Class: Gluco/Corticosteroid Action: These enter target cells and bind to cytoplasmic receptors, initiating many complex reactions that are responsible for anti-inflammatory and immunosuppressive effects. These drugs (Prednisone) also affect K+, Na and H20 levels in the body. These are used for the short-term treatment of many inflammatory disorders, to relieve discomfort and to give the body a chance to heal from the effects of inflammation. (Karch pg 468) Reason Patient is taking: My patients admitting diagnosis is cellulitis, and with this condition there is a lot of swelling. This drug is to help alleviate the inflammation due to his diagnosed condition of cellulitis. At the time I cared for S.N. he rated his pain level at a zero. S.N.’s WBC level was a 7.4 on 4/5/04. His Neutrophil level was at a 60.3 and his Monocyte level was 11.8. Although these indices are within normal limits they are on the higher end of normal limits indicating that the inflammation process is occurring. Patient teaching would include advising S.N. that a side effect of this drug is suppressed natural immunity and educating him of the importance of staying healthy by avoiding people who are sick and building up his already suppressed immunity with a good diet. (Nutritional consult on 4/6/04)