Chapter 14 Abnormal Meiosis Web Assignment Name__________ Hour_____ Part I Go to the Web Address: http://www.massasoitbio.net/courses/136/136_courseassets/cummings_animations/karyotype.html View the animation to learn how a karyotype can be prepared. Part II A karyotype is an organized profile of a person's chromosomes. In a karyotype, chromosomes are arranged and numbered by size, from largest to smallest. This arrangement helps scientists quickly identify chromosomal alterations that may result in a genetic disorder. To make a karyotype, scientists take a picture of someone's chromosomes, cut them out and match them up using size, banding pattern and centromere position as guides. Go to the Web Address: http://learn.genetics.utah.edu/content/begin/traits/karyotype/ Make the karyotype and turn it in to Mrs. Wald. If the above link does not work, try this one: http://learn.genetics.utah.edu/content/chromosomes/karyoty pe/ Part III Go to the Web Address : http://www.biology.arizona.edu/human_bio/activities/karyotyping/karyotyping.html Read the “Introduction” and continue on to “Patient Histories” . Complete each of the patients karyotypes by examining the single chromosome on the left side of the instructions and then clicking on the chromosome number where its homologous partner is located.Once you have paired up all of the homologous pairs correctly, a note of congratulations appears and you are asked to characterize the patients karyotype and then asked to give the patient a diagnosis based upon their karyotype. Patient A’s Karyotype Questions 1. (A 1.) What notation would you use to characterize Patient A's karyotype? ________ 2. (A 2.) What diagnosis would you give patient A?______________ Patient B’s Karyotype Questions 3. (B 1.) What notation would you use to characterize Patient B's karyotype? (See Pg 271 Text) _________ 4. (B 2. ) What diagnosis would you give patient B? _____________ Patient C’s Karyotype Questions 5. (C1) What notation would you use to characterize Patient C's karyotype? (See Pg 271 Text) _________ 6. (C2) ) What diagnosis would you give patient C?______________ Part IV Go to the Web Address : http://bluehawk.monmouth.edu/~bio/karyotypes.htm 1. Click on Picture of Finished Karyotype – Notice how a completed karyotype is supposed to look. 2. Click on Graphic of Finished Karyotype – These chromosome graphics are supposed to help you identify the different types of chromosomes 3. Complete the Normal Male and Normal Female Karyotypes Complete each of them and print out each karyotype when you are finished. Make sure the diagnosis and sex of the individual are filled in before you print them out. 4. See if you can determine which of the unknowns E through X are one of the following Down Syndrome, Klinefelter Syndrome or Turner Syndrome. Find, complete and print out each of the above correct karyotypes. Make sure the diagnosis and sex of the individual are filled in before you print them out. Also include the Unknown letter. Good Luck!