The Villanova Chemist “Christmas” 2005 Edition January 2006 From The Chairman Greetings from the Chemistry Department, and Happy 2006! It has been an extremely busy year at Villanova, and I’m excited to tell you about the many things that have happened this year. Changes continue to abound in the Chemistry Department. Mike Spritzer has retired from the Department after 39 years of service, and has moved out to Lancaster County (or “Villanova West”, as we like to call it) to join several other Chemistry faculty who have left recently. Building modifications are happening as we upgrade facilities to add a new x-ray diffractometer to the Department. Thanks to our newest faculty member, Dr Timothy Dudley, we’ve also set up a new Departmental computing facility loaded with a PC computing cluster and a gaggle of Apple G5 servers. The organic labs have been blessed with two new Perkin-Elmer FT-IR spectrometers with Attenuated Total Reflectance sample accessories (no more KBr films!), and a solvent purification system has eliminated our need for THF stills. And finally, we have just received approval to offer a new undergraduate major in Biochemistry. I mentioned last year that our Department web site contains lots of interesting tidbits of information. The site has undergone a total facelift this year (thanks to Profs Anthony Lagalante and Amanda Grannas), and has even more stuff and pictures to look at. If you’d like us to contact you by email, please send your email address either to me (barry.selinsky@villanova.edu), Oliver Ludwig (oliver.ludwig@villanova.edu), or Nancy Proud (nancy.proud@villanova.edu). We would be happy to put you on our mailing lists. We can also post your email address on our website to give other Villanova alums the chance to contact you if you’d like. Finally, if you’ve accomplished something noteworthy that you’d like to tell the world, send me the information by email and I’ll post it on our “Department News” section of the site. Faculty News –As mentioned above, we have added Dr Timothy Dudley, a physical/theoretical chemist, to our Department faculty. Also joining us this year are Ms Heljena McKenney and Dr. Laurie Morton, who are covering courses generated from sabbatical leaves. On that note, Dr Carol Bessel is currently on a leave of absence from the Department as she pursues a rotating Director position at the National Science Foundation. Also, Dr Joseph Rucker is leaving us to accept a position at Integral Biosciences in Philadelphia. We have just completed a Biochemistry faculty search, and are in the process of submitting offers to two outstanding candidates. Students - We are extremely proud of the Villanova Chemistry Class of 2005. Their names and affiliations follow: BS Graduates: Elise Birkett (PhD program, Boston University); Jonathan Blackwell; Jason Champion (Law School, University of Southern California); Kimberly Dallas (MA program in Education, Villanova University); Heath Evans (Dentistry, University of Oklahoma); Steve Gallagher (Cephalon); Peggy Greene (DuPont); Riffard Jean-Gilles (MS program, Villanova University); Dana Lilli (applying to Medical School); Mariana Melendez-Diaz (MS program, Villanova University); Annsley Miller (Occupational Therapy, New York University); Greg Riviello (PhD program, Princeton University); Luci Safi (Philadelphia College of Osteopathic Medicine); Jenny Shultz (Baxter); Chris Saeui; Tricia Sladicka (Merck); Kathleen Spencer (PhD program, California Institute of Technology); Steve Ten Eyck; Richard Tyburski; Mike Werner (MS program in Environmental Science, Indiana University). Congratulations all! MS Graduates: Navneeth Daundikhed (GlaxoSmithKline); Oscar Miranda (PhD program, University of Massachusetts); Theresa Henry (GlaxoSmithKline); Ruth Hough (IsoSciences); Gopi Kasi; James Nelson (GlaxoSmithKline); Damien Fink (Centocor); Andrea Bondy (Centocor); Charles Bornhoeft (Wyeth). (Not so) Random Thoughts Our Admissions Office has instituted a Science Open House in the fall, and this year a parent of a potential student asked me about the state of the chemical industry and the potential for future employment. If you look at statistics published by the American Chemical Society, you find the job market for chemists is becoming more competitive, with jobs going overseas and downsizing occurring in the pharmaceutical industry. That said, I am optimistic about the future of Villanova chemists. If you look at where our students have “landed” after graduation, most have either found jobs in their major or have been accepted into some fine graduate programs. When students come to me for advice about courses, I always suggest that they challenge themselves with more difficult courses. I remind them about the difficulty of being a chemistry major, and how few students can handle the rigors of the discipline. You should be proud of your accomplishments. This is a landmark year for me and my family. My daughter is graduating from college in June (with a Chemistry degree, of course!), and my son is graduating from high school and looking at colleges for the fall. But as you know, change is inevitable. I hope that you enjoy life as it moves and changes around you. Barry Selinsky Professor and Chairman, Department of Chemistry chemistry working under both Dr Alexander Gero and Fr Jenkins. With a growing family he could not afford to continue to work at Villanova as an instructor. He left Villanova and went to the Warner Co and then to Fischer & Porter from which he retired in 1982. Jim. [The latest Villanova Magazine notes that Francis Garvin '50 died on 5 Aug 05.] ********* From Tony Zacchei ’61 MS ’64: Just received the newsletter and thought that it is about time that I put my name on the Alumni list. Checked out the web site and noticed that almost 50% of my class is listed. I'll have to remind my daughter, who also graduated from VU with a chemistry degree, to add her email address to the list. And later Tony continues: Hi: Just spoke to Michelle and she asked me to request that you put her name on the alumni list if I contact you. So here goes. Her name is Michelle Zacchei Toth ’91. FYI she is married and has three kids. She remembers you teaching her in freshman chem classes and enjoyed your lectures. Tony. [Our web page chemistry.villanova.edu/societies/alumni.html has data on lost and deceased alums as well as email addresses for those who offered them.], Alumni Notes Oliver Ludwig ’57 Editor Volume 22, begun February 2005 Well here, for the twenty second year, is what we have learned about our Department and its progeny over the last year. Just as some people collect stamps, your editor collects and disseminates biography. [Editorial comments are in square brackets. By the way, your editor has just become the last of the Old Guard, since Profs Mike Spritzer retired last spring and John Wójcik will retire this spring.] Retired Prof Tom Doyne emails: All's well in these parts. I have adopted the more relaxed aspects of Amish farm life – early to bed, early to rise, etc, but not the black hat, beard, nor horse and buggy, etc. I am still doing substitute teaching at the local high school. It continues to be fun – imparting "gems of wisdom from the old days". I have joined the local YMCA and work out on the machines three times each week – must bring the body back in shape!! Tom. Necrology: Jim Markham ‘50 emails a correction on a death notice in our last issue: Here are the facts about James L. Henry. He never taught in the C&F School; that was a Bill Henry. Jim Henry got his BS in Chemistry from Villanova College in 1944 and like so many at that time went directly into the army. In 1946 he came back to Villanova as an instructor and worked as such until 1956. He was very well liked. He took care of freshman recitations and labs. But his major long-term activity was as the laboratory instructor in organic Hank Whalen ’57 has retired as Director of Industry Relations for the American Chemical Society. From the Villanova Magazine Fall ‘05: Tony Silvestri ’58 has retired from Mobil in NJ. He’s in the Inventors Hall of Fame with 28 patents and more than 60 publications. As well, he has endowed Villanova’s Chemistry Department with an annual Lectureship. From Richard Cordell ’61: I have just completed my 40th year of teaching chemistry at Heidelberg College in Ohio. I have also just retired since my wife works for Microsoft and has been transferred to their Redmond headquarters. I still enjoy teaching and interaction with students, so I may try to look for an adjunct position after the dust of the move settles. Another interesting tidbit (at least from my perspective): I have been involved in reading AP chemistry exams on for many years (started in 1969) and last June at the Reading at Clemson I bumped into a 1960 alum whom I knew back then. I didn't recognize him at first but he had a Villanova sweatshirt on so I naturally went over to see who he was. Turned out he was John Schmidt ’60, who now is Professor of Chem at Shepherd University in West Virginia. We had a nice reunion and reminisced about the "good old days" at VU. I also note that my year (1961) has a pretty good representation among those listed on the chem website. I think there were 10 in my year, and 7 of them are listed. Hooray for us!! Anyway, I got a good start at Villanova with Drs Quam, Jenkins, Markham, et al. Richard Cordell. Chris Uzelmeier ’63 writes to Prof Barry Selinsky: Thanks for the Villanova Chemist. Always enjoy reading it and looking for news about the people I went to school with. Some other info about me that you may or may not have: BS Villanova, Chemistry 1963, PhD Case Western Reserve University 1967, Shell Chemical Co 1967-1996, Union Carbide Corp 1996-2001, Dow Chemical Co 2001, now retired. Wife Kathleen, married 41+ years. Children: two sons; Tom, age 40 and Bill, age 38, one grandchild. Hobbies: Golf, Travel. Chris. George DeTitta ’69 writes from SUNY Buffalo: In July’ 05 I was awarded one of the ten Center grants from the NIH Protein Structure Initiative for the development of tools for structural genomics. This has allowed (forced, really) me to go back into the lab on a daily basis, and that's been good for my mental well-being. An administrative life is not much fun at all for a chemist at heart. The $17M grant unites seven different labs in seven different cities to work on all aspects of structural biology, in particular on methods to do the work more easily, quickly, inexpensively. Our targets are proteins from bakers' yeast, especially protein-protein complexes and membrane-associated proteins. Plans for an early retirement look less promising however. George. From Jim Riehl ‘70: I am in my sixth year as Dean here in Duluth. A piece of news is that last October I was awarded the Gold Medal of the University of Wrocław during the opening ceremonies of their academic year. This award was given to recognize my involvement for almost 15 years in cooperative research and education projects with this university. [Jim is McKnight Leadership Chair and Professor of Chemistry and Dean, College of Science and Engineering University of Minnesota Duluth.] From Ernie Kelly MS’74, PhD’77: This has been a blessed year for us in the Kelly house. We became grandparents in September with the birth of a daughter to our oldest son. Our second son returned from a year in Iraq with the 20th Airborne Combat Engineers and is stationed at Fort Bragg, NC. I completed my first full year with a local Bio- Pharmaceutical company, Cephalon, in West Chester PA. God has truly blessed us this year. All the best to you and alums, Ernie. From Sr Joan Riethmiller MS ’75 (S. Richard Christi): I wanted to tell you that I still find the newsletter interesting. I went to the web site for the "lost" chem students. I can tell you that the first name on the list is a Ms, not a Mr [Aysegul Akgerman MS’74] was from Turkey. [VU’s computer must have made a misteak!] I regret that you don't have info on Tom Lan MS’75 and also the young man from India we called Josh. [Phanibhushan Joshipura PhD ‘74]. I was surprised at seeing Gene Whitaker PhD ’75 as lost – he's my dentist! He told me he didn't receive a newsletter. [We have his address now; he’ll get this one!] Thank you for all you do to keep the "homey" spirit alive. I always look forward to hearing from the Chem Dept, even though now I have been working the past ten years in Kensington – a rough part of Philly. Blessings on your work. Joan. From Mike Lamb ’75: Recently I was invited teach a two week seminar on internal medicine in Iizuka Japan. I greatly enjoyed my time in Japan as a visiting professor. I received many awards and honors while there and I have been invited to return next year. My teaching style is very much based on the problem-solving Ludwig approach that I learned at Villanova. [They say a teacher never knows where his influence ends – but Japan must be pretty close to it! Mike has endowed a lectureship at Villanova on “Augustine and Modern Science” which proved pretty timely now that Evolution has been in the news so much lately.] Diane Schneider '76 is Associate Director of Clinical Research at Endo Pharmaceuticals in Chadds Ford PA. Mary Kaiser PhD ’76 emails: I am currently a Research Fellow in DuPont's Corporate Center for Analytical Sciences in Wilmington, DE. Last year I was busy co-authoring papers (7 accepted for publication so far) and preparing technical presentations (15). I'm also active in the ACS Division of Analytical Chemistry's Graduate Fellowship Committee and am chairing the Eastern Analytical Symposium's award committee. Mary. Sirirat (Ho-Ampawanwong) Kokpol PhD’79 is Head of the Chemistry Dept of Chulalongkorn University in Bangkok. She writes that they have 78 faculty and 40 support staff. [I don’t envy her paperwork!] From Kevin Gosselin ’82: No news other than, "Does anyone have any spare basketball tickets?" Still doing finance work vs. chemistry. Not sure how to break into a science career after 25 years of doing everything but! Kevin. Mark Czekaj ’86, MS ’89 writes: At present Andrea and I and our three kids are living in Doylestown, PA and I work in Bridgewater NJ. My oldest son is now 14 and my middle son is 12, my youngest a daughter is 9. Things at work have been OK considering we were taken over by Sanofi about a year ago. They left our site pretty much the same with no layoffs within chemistry with the exception of the department head. It could have been far worse. I still keep in contact by either e-mail or phone with Scott Bolton MS ‘91, Vincent Manetta MS ‘92, Janet Gagnon MS ’89 PhD ’93, Bill Mathew PhD ‘92 and recently got to spend some time in San Diego with Ann (Bradley) DiMasi MS ‘89 at an ACS meeting. I work with Charles Gardner ’75 MS ‘82. I have been doing traditional small molecule synthesis for pretty much my whole career and have enjoyed both the work and the new technical advances that make my job easier. I have happily adopted the use of an automated flash column system to take the drudgery/bottleneck out of compound purifications. Does your department have any of these instruments? They save our company a lot of money by reducing the amounts of solvents used. We run linear gradient elutions and obtain pure compounds without having to mix ethylacetate/heptane manually only to have to figure out what to do with the left over "mix". I hope to make it to Villanova someday and will stop in and say ‘Hi’ if I see your door open. Mark. Later Mark writes: I recently had lunch with a few Villanova chemistry graduate alumni over the holidays. They included Vince Manetta, Scott Bolton and Chip Davis MS ‘94. At one time we all worked at Rorer in King of Prussia. Various mergers and career goals have separated us but we still manage to get together for lunch every year sometime during the holidays. Mark. From Chris Quigley ’86: Good to hear from you. I was wondering when the next issue was being released. Things here in Boston are going great. Wife and kids are both doing great as well. Kids are five and seven and getting big as they are known to do. I recently celebrated my 15th anniversary of being in chiropractic practice in downtown Boston. I also recently retired from professional politics having attained the office of Secretary Treasurer of the International Chiropractors Association. I have been following our basketball efforts closely and I was greatly disappointed to see that VU was not making any trips to either Providence or BC (their fault) this season. Thank you for keeping the effort going. I always look forward to the newsletter. Yours in Health, Chris. Ricardo Alvarado MS ’90, PhD ’92 was decorated with the Order "José de Marcoleta", in the Degree of Great Cross, in recognition of his efforts in the service of Nicaragua as its Ambassador to Denmark, Finland and Ireland. [Just think of the temperature difference when Ricardo goes home!] Gary Speier MS ’91 emails: All is well here in Minnesota. I recently became a Partner at SLWK (patent boutique law firm here in Minneapolis), we recently moved to the suburbs and my wife is pregnant with our second child (due date mid-July). We spent Christmas at my in-law's farm in southern Minnesota. Growing up, I never thought I would be driving a John Deere tractor on Christmas day. It was a hybrid scene of Norman Rockwell and Charles Dickens. Gary. Tere Diaz ’91 writes to Prof Bob Giuliano: Dr G, Greetings and salutations! I was requesting a transcript from VU and decided to check the chemistry department webpage. Glad to see you are still teaching. I'm well, still at NIH. Have managed to pick up skiing and scuba diving along the way. Went diving in Okinawa last November. Beautiful! Do you remember a grad student, Irene Campbell MS ‘91? She is getting married this summer, so I'll have to swing around for that. Drop a line when you have a chance. Tere. Kellie (Mraz) Cutrona, ’92 writes to Prof Barry Selinsky: Just an update: Currently Sr. Logistical Analyst supporting Merck (West Point PA) Research Division logistical projects. I am married now with two children (five and three). I have been working at Merck since graduation. While at Merck I worked in Research (Medicinal Chemistry) for about seven years and then I moved to Manufacturing (Materials Management) and I have been there for about six years. While at Merck I completed my Master's degree in Chemistry from Lehigh University (Merck has a satellite program with Lehigh). Kel. Pat Grohar ’95 writes: I look back at my experience at Villanova as one of the highlights of my life. I feel a tremendous amount of gratitude towards the faculty and Villanova community for what I learned while a student there as well as for making life great for a few years. As a result, I feel that I have something that I can give back to the current chemistry majors. I propose an opportunity for the chemistry majors to meet with me to discuss life after Villanova. I’m a 1995 BS Chemistry 2001, PhD in Chemistry -Wayne State University, 2003, MD Wayne State University 2003. Residency training in pediatrics - Johns Hopkins University 2005-2006 (currently). Research Track in residency and therefore spending a year at the National Institutes of Health working on developing novel chemotherapies for pediatric osteosarcoma, 2006-2009. (Already accepted to fellowship for the combined Johns Hopkins/National Institutes of Health Fellowship in Pediatric Oncology.) Since I have done both a true PhD program and a medical program I feel there is much I could inform the students about. Pat. [We have been trying to schedule Pat into our Professional Development Seminar, now required of all Chem majors each semester.] From Kevin Orlando ’01: I just received your email and wanted to let you know Kelly and I now have a beautiful baby girl. Samantha Nicole Orlando was born on October 24, 2005. She weighed in at 8 lb 0 oz and 21 inches. Both mom and baby are doing very well. I look forward to reading the news letter soon! Kevin. [Our congratulations to all involved!] From Bob Canelli ’03: I am at St. George's University School of Medicine in the Caribbean, more specifically on the island of Grenada. My first choice was UConn, however, I never made it off the waiting list. So my next option, which is proving to be an amazing choice, was to come to Grenada. The island is beautiful, I can hardly believe it will be my home for the next two years. Every day is about 7580 degrees and sunny. The water is turquoise and the sand is white. We are currently in the rainy season (hurricane season) however we are south of the hurricane belt so we are not supposed to get hit with any. Last year at this time was the first time in 50 years that the island did get hit, so it is not invincible. The rainy season consists of rain for about 15 minutes per day, so it’s not very rainy at all. It is very humid however. I have made time between studying to go to the beach, snorkeling, and going on excursions to the open air fish and meat markets in town. The school is a four year program. However, I will be in Grenada for a year and a half, St Vincent (another small island) for six months, and then I am back in the states for two more years. So I'm not gone for that long. I have a feeling that it’s going to fly by. All of my "extracurricular excursions" come in between class obviously. I've been here for a few weeks and I've learned more than you can imagine. I am taking anatomy, biochemistry, embryology, and histology now. I really like anatomy. My cadaver's name is Dorris. She has taught me so much already. Last Friday we dissected her thorax and I was able to hold her lungs and heart in my hand. It was really really exciting!! I'm doing well in biochemistry which is one of the hardest classes that medical school students face. It must obviously be from my excellent background in chemistry that I got at ‘Nova. I study about six hours a day (something I never did at ‘Nova but don't tell any of the professors that!!!), so free time is limited. However I have found a great spot to study on a cliff overlooking the school, the beach, and the airport. It’s gorgeous! I miss you guys and Villanova a lot and I think about you all often, I hope to hear back from you soon! Bob. Chris Cummings ‘04 emails Prof Bob Giuliano from his grad work at Yale. He says he's "learning an awful lot". He takes Organic Synthesis from the advisor to Heidi Shimp ‘03 and Justin Belardi ‘04. He expects to work for the advisor to Erin Pusateri ‘01. [It seems that Villanova has a pipeline to Yale!] It has been quite the hectic semester, and I can't wait for classes to be over. In addition to classes I am teaching twice a week and grading a stack of papers 5-6 inches tall each week, and I am beginning to appreciate the life of a teacher who has to grade constantly. I will be joining Andy Hamilton's lab, and my research will be on a new grant he has for alpha helix mimics which hopefully will combat cancer. This is the same lab that Erin Pusateri is in. I am excited to start, but right now I am just reading background research and will most likely get my hands dirty in the summer. Chris. From Greg Riviello ’04: Things are going well for me at Princeton; I've joined the research group of Dr Herschel Rabitz in the Chemistry Department. He is a theoretician whose work is centered around the principles of quantum control, which involve the use of tailored laser fields to induce very specific constructive and destructive interferences within molecules or materials. The specificity of these controls has been developed to the extent that it is pos- sible, using a laser, to drive a molecule into a specific conformation or break a particular bond. Greg. If you enjoyed reading about some of your old classmates, please think of reciprocating: write us and you’ll see your news in our next edition. If you would like to add your email address to our web site, please email me and I’ll add it. All the best… Alumnically, Ol Ludwig ‘57 6 March 2016 Chemistry Department Villanova University 800 Lancaster Ave Villanova PA 19085-1699 ADDRESS SERVICE REQUESTED Non-Profit Organization U.S. Postage PAID Villanova University