Мodule 5
Analysis of the quality of drugs from the group of biologically active substances of natural
origin and extemporal preparations
1. Determine the molecular mass of the ascorbic acid equivalent at its assay by alkalimetry,
direct titration:
A. *М.m.
B. М.m./2
C. М.m./4
D. М.m./8
E. 2 М.m.
2. Choose the reagent for ascorbic acid identification:
A. *Silver nitrate solution, nitrate acid
B. Dragendorff’s reagent
C. Barium chloride solution
D. 2,4-dinitrochlorbenzene
E. Hydroxylamine hydrochloride
3. Calcium ion in the calcium pangamate can be detected with following reagent:
A. Silver nitrate
B. *Ammonium oxalate
C. Hydrochloric acid
D. Hydrogen peroxide
E. Potassium dichromate
4. Assay of calcium pantothenate is conducted by the following method:
A. Argentometry
B. Iodometry
C. Permanganatometry
D. *Complexonometry
E. Alkalimetry
5. What compound does belong to vitamins of the alicyclic row?
A. Thiamine bromide
B. *Retinol acetate
C. Vikasol
D. Ascorbic acid
E. Nicotinic acid
6. What reagents can be used for ergocalciferol identification?
A. 2,4-dinitrochlorobenzene, potassium hydroxide alcohol solution
B. Sodium nitrite, β-naphthalene alkaline solution
C. Chloral hydrate, chloroform
D. *Acetylchloride, antimony (ІІІ) chloride, chloroform
E. Cerium sulfate, diphenylamine
7. Calcium pantothenate is a vitamin preparation, in the medical practice it is used under the
name – vitamin:
A. *В5
B. В15
C. ВС
D. В6
E. В3
8. Retinol acetate by the chemical method can be obtained from:
A. Ergosterine
B. Fructose
C. L-streptose
D. *Citral
E. Maltose
9. Ergocalciferol is used in the medical practice for the treatment of:
A. Blood diseases
B. Goiter
C. Cataract
D. Atherosclerosis
E. *Rachitis
10. Assay of ascorbic acid according to the SPhU requirements is conducted by the following
method:
A. Complexonometry
B. Acidimetry in non-aqueous environment
C. Alkalimetry in aqueous environment
D. Iodatomerty
E. * Iodomerty
11. Ascorbic acid in industry is obtained from:
A. Furfural
B. Fructose
C. L-streptose
D. *D-glucose
E. Maltose
12. Gluconic acid residue in the calcium pangamate molecule is detected by the following
solution:
A. Silver nitrate
B. 2,6-dichlorophenolindophenol
C. Ammonium oxalate
D. *Iron (ІІІ) chloride
E. Sodium hydroxide
13. Calcium pangamate belongs to the vitamins of:
A. Alicyclic row
B. Aromatic row
C. *Aliphatic row
D. Heterocyclic row
E. Polyene row
14. Residue of -alanine in the calcium pantothenate molecule is determined by usage of the
following solution:
A. CuSO4 in H2SO4
B. Sodium nitroprusside
C. *CuSO4 in NaOH
D. Formaldehyde
E. CuSO4 in HCl
15. What reagent can be used to identify retinol acetate in the presence of chloroform?
A. Hydrochloric acid
B. *Antimony (ІІІ) chloride
C. Sodium nitrite
D. Vanillin
E. Sodium nitroprusside
16. Ergocalciferol also can be named as vitamin:
A. В5
B. В2
C. Е
D. *D2
E. А
17. For calcium-ion detection in the calcium pangamate molecule the following reagent is used:
A. Silver nitrate
B. *Glyoxal hydroxyanil
C. Hydrochloric acid
D. Hydrogen peroxide
E. Potassium dichromate
18. Calcium chloride in the calcium pangamate substance is quantitatively determined by the
following method:
A. Alkalimetry
B. Argentometry by Mor’s method
C. *Argentometry by Folgard method
D. Acidimetry
E. Complexonometry
19. Molecular mass of the ascorbic acid equivalent at the quantitative determination by
iodometric method equals:
A. М.m.
B. *М.m./2
C. М.m./4
D. М.m./8
E. 2 М.m.
20. Chemical name γ-lactone-2,3-dihydro-L-gulonic acid the following compound has:
A. Vikasol
B. Rutin
C. Ergocalciferol
D. Riboflavin
E. *Ascorbic acid
21. Choose the reagent for ascorbic acid identification:
A. Dragendorff’s reagent
B. Barium chloride solution
C. *2,6-dichlorophenolindophenol
D. 2,4-dinitrochlorobenzene
E. Hydroxylamine hydrochloride solution
22. Pharmacist-analyst did calcium pangamate identification by hydroxamic reaction. What
functional group does this reaction identify in the structure of calcium pangamate?
A. Ion Са2+
B. *Ester group
C. Hydroxide group
D. Methyl radical
E. Tertiary amine
23. Calcium ion in the calcium pangamate can be detected by following method:
A. Argentometry
B. Permanganatometry
C. Alkalimetry
D. *Complexonometry
E. Acidimetry
24. Calcium pantothenate is used in the medical practice for the treatment of:
A. *Metabolic disorders
B. Eyes diseases
C. Heart diseases
D. Gastro-intestinal tract disorders
E. Gynecological diseases
25. Retinol acetate is a vitamin preparation, in the medical practice it is used under the name –
vitamin:
A. В5
B. D2
C. Е
D. К
E. *А
26. What compound does belong to vitamins of the alicyclic row?
A. Thiamine bromide
B. Calcium pangamate
C. Vikasol
D. *Ergocalciferol
E. Nicotinic acid
27. Ascorbic acid belongs to the vitamins group of:
A. Pyrimidine derivatives
B. Pterine derivatives
C. *Aliphatic row
D. Tropane derivatives
E. Acridine derivatives
28. Vikasol is a synthetic analog of vitamin:
A. А
B. В
C. С
D. Е
E. *К
29. Tocopherol acetate has the following chemical name:
A. Pregnane–4-ol-21-dione-3,20-21 acetate
B. Pregnene–4-diol-17-2,21-trione-3,11,20-21 acetate
C. Pregnene–4-triol-11,17, 21-dione-3,20-21 acetate
D. Trans-9,13-dimethyl-7-(1,1,5-trimethyl-cyclogen-5-yl-6)nontetraene-7,9,11,13-one–15
acetate
E. *(+)-2,5,7,8,-tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-acetoxychromane
30. Routine is present in the following tablets content:
A. Papazol
B. No-spa
C. *Ascoroutine
D. Reoperin
E. Citramone
31. Nicotinic acid belongs to the vitamins group of:
A. Piperidine
B. Pyrimidine
C. *Pyridine
D. Pyrazolone
E. Pyrazol
32. What smell do you fell during the nicotineamide heating with crystalline sodium carbonate?
A. Aniline
B. *Ammonium
C. Acetoacetic ether
D. Fresh apples
E. Bitter almond
33. At the pyridoxine hydrochloride assay by acidimetry in non-aqueous environment
Hg(CH3CОO)2 is added for:
A. *Halogen bonding in low-dissociated compound
B. Enhance hydrolysis of the final product
C. Inhibition of the final product hydrolysis
D. Displacement of the reaction equilibrium to the right
E. Displacement of reaction equilibrium to the left
34. Chloride-ion in the pyridoxine hydrochloride molecule can be detected with the usage of the
following reagents:
A. AgNO3, H2SO4
B. *K2Cr2O7, H2SO4 , diphenylcarbazide
C. K2Cr2O7, diphenylcarbazone
D. AgNO3, NaOH
E. Diphenylcarbazide
35. Tocoferol acetate identification can be conducted with the following reagents:
A. Conc. HCl at the heating
B. KOH solution at the cooling, H2SO3
C. *K3[Fe(CN)6] solution in alkaline environment
D. Vanillin in glycerin solution
E. Hydroxylamine hydrochloride
36. What compound is an aglycone in the routine molecule?
A. Streptidine
B. *Quercetin
C. Strophantidine
D. Digitoxygenine
E. Digoxigenin
37. Which of the following compounds has chemical name 2,3-dihydro-2-mathyl-1,4naphthoquinone-2 sulfonate?
A. Ergocalciferol
B. Riboflavin
C. *Vikasol
D. Cocarboxylase
E. Rutin
38. Tocopherol acetate in the medical practice is used for the treatment of:
A. *Functional disorders of the sexual organs
B. Scurvy
C. As antioxidant mean
D. Liver cirrhosis
E. As antiseptic mean
39. Assay of routine is conducted according to the AND requirements by the following method:
A. Refractometry
B. Polarimetry
C. Potentiometry
D. Paleography
E. *Spectrophotometry
40. Choose the chemical name of nicotinic acid:
A. Pyrimidine-3-carboxylic acid
B. Piperidine-3-carboxylic acid
C. Pyrimidine-2-carboxylic acid
D. *Pyridine-3-carboxylic acid
E. Pyridine-4-carboxylic acid
41. What smell do you feel during the nicotineamide boiling with sodium hydroxide?
A. Aniline
B. *Ammonium
C. Phenol
D. Pyridine
E. Bitter almond
42. Determine the molecular mass of the pyridoxine hydrochloride equivalent at its assay by
acidimetry in non-aqueous environment:
A. 2 М.m.
B. ½ М.m.
C. 1/4 М.m.
D. *М.m.
E. 1/8 М.m.
43. Pyridoxine hydrochloride belongs to the vitamins, derivatives of:
A. Piperidine
B. Pyrimidine
C. *Pyridine
D. Pyrazolone
E. Pyrazone
44. The nicotinic acid content of the injection solutions in accordance with the AND
requirements was determined by the following method:
A. Alkalimetry
B. Acidimetry in non-aqueous environment
C. *Cooper-iodometry
D. Gravimetry
E. Refractometry
45. What gas will evaporates after the nicotinamide heating with an alkali solution?
A. CO2
B. N2
C. *NH3
D. O2
E. CO
46. Medical drug vikasol has the following chemical name:
A. Sodium salt of 6-phenylacetylamino-penicillanic acid
B. Sodium salt of p-aminosalicylic acid
C. *Sodium 2,3-dihydro-2-methyl-1,4-naphthoquinone-2-sulfonate
D. Sodium 5-ethyl-5-(2-amyl)-barbiturate
E. Sodium p-(2,3-dimethylphenyl)-anthranyl
47. Assay of tocopherol acetate after hydrolysis according to AND requirements is conducted by
the following method:
A. Complexonometry
B. Acidimetry in aqueous environment
C. Alkalimetry in non-aqueous environment
D. *Cerymetry
E. Gravimetry
48. Pyridine cycle in the nicotinic acid is detected with:
A. Potassium permanganate solution
B. 2,6-dichlorophenolindophenol
C. *2,4- dinitrochlorobenzene
D. Iodostarch paper
E. Felling reagent
49. Assay of nicotinamide according to the SPhU requirements is conducted by the following
method:
A. *Acidimetry in non-aqueous environment
B. Iodometry
C. Permanganatometry
D. Acidimetry in aqueous environment
E. Alkalimetry in non-aqueous environment
50. Which of the following substances has chemical name (5-hydroxy-6-methylpyridine-3,4diyl)-dimethanol hydrochloride?
A. Novocain hydrochloride
B. Cocaine hydrochloride
C. Morphine hydrochloride
D. *Pyridoxine hydrochloride
E. Pilocarpine hydrochloride
51. Nicotinamide belongs to vitamins derivatives of:
A. Piperidine
B. Pyrimidine
C. *Pyridine
D. Pyrazolone
E. Pyrazone
52. Vitamins of К group belong to the:
A. Aromatic row
B. Aliphatic row
C. *Alicyclic row
D. Heterocyclic row
E. Polyene row
53. What reagents can be used for tocopherol acetate identification?
A. Conc. HCl at the heating
B. Alcoholic solution of KOH at the heating, conc. H2SO4
C. *Solution of K3[Fe(CN)6] at the presence of chloroform
D. Vanillin in the glycerin solution
E. Hydroxylamine hydrochloride
54. The sugar part in the routine molecule is:
A. Streptobioseamine
B. Digitoxose
C. *Ramnose
D. Ramnose, glucose
E. Glucose
55. Which of the following methods is not used for the thiamine hydrochloride assay?
A. Gravimetry
B. Alkalimetry
C. Acidimetry in non-aqueous environment
D. *Bromatometry
E. Fluorimetry
56. What reagents are used for the bromine-ion detection in thiamine hydrobromide molecule?
A. K3[Fe(CN)6], NaOH, butyl alcohol
B. AgNO3, NH3
C. NaNO3, HCl, -naphthalene alkaline solution
D. *Chloramine, HCl, chloroform
E. Sodium nitroprusside, KOH
57. Choose the specific admixture in the riboflavin molecule:
A. Leukoribine
B. Cocarboxylase
C. Leukogen
D. Leukobase
E. *Lyumiflavin
58. What reagents can be used to identify riboflavin?
A. Sodium sulfate, silver nitrate
B. Diluted sulfate acid, ninhydrine
C. *Concentrated sulfate acid, silver nitrate
D. Sodium nitroprusside, ninhydrine
E. Silver nitrate, sodium nitroprusside
59. Choose the chemical name of cocarboxylase:
A. 3,7-dimethylxanthine
B. Menthol ester of isovaleric acid
C. Stearic ester of laevomycetin
D. *Hydrochloride of thiamine diphosphate ether
E. Ethyl ester of p-aminobenzoic acid
60. Cyanocobalamin is used in medical practice for the treatment of:
A. Schizophrenia
B. *Anemia
C. Allergy
D. Cold diseases
E. Radiculitis
61. What reagents can be used for the detection of chloride ions in the thiamine hydrochloride
molecule?
A. K3[Fe(CN)6], NaOH, butyl alcohol
B. *K2Cr2O7, H2SO4, diphenylcarbazide
C. NaNO3, HCl, -naphthol alkaline solution
D. K2Cr2O7, chloroform
E. Sodium nitroprusside, KOH
62. Antianemic action of cyanocobalamine is cased due to the presence in its structure molecule
of:
A. *5,6-dimethylbenzimidazole
B. Cobalt
C. Ribofuranose
D. Corrine
E. Cyano-group
63. Folic acid gives reactions with salts of heard metals due to its properties:
A. Basic
B. *Acidic
C. Amphoteric
D. Oxidative
E. Reductive
64. Thiamine hydrobromide is a vitamin preparation, in the medical practice it is used as
vitamin:
A. В5
B. В2
C. В6
D. *В1
E. В3
65. What compound has chemical name hydrochloride of thiamine diphosphate ether?
A. Thiamine hydrochloride
B. Pyridoxine hydrochloride
C. Riboflavin
D. Cyanocobalamin
E. *Cocarboxylase
66. Choose the method of riboflavin assay in the substance:
A. Acidimetry in aqueous environment
B. Alkalimetry in aqueous environment
C. *Alkalimetry by the substitute
D. Permanganatometry
E. Iodometry
67. Analyst conducts identification of the folic acid by the reaction with:
A. *Salts of heard metals
B. Salts of alkaline metals
C. Marcy reagent
D. Hydrochloric acid
E. Oxides of heard metals
68. Analyst conducts assay of thiamine hydrobromide by argentometry (Fayanse method).
What indicator (1) is used? What is the equivalent mass of thiamine hydrobromide (2)?
A. 1–methyl orange, 2–М.m.
B. 1–potassium chromate, 2 – 1/2 М.m.
C. 1–bromthymol blue, 2 – М.m.
D. *1–bromthymol blue, 2 – 1/2 М.m.
E. 1–iron-ammonium alums, 2–М.м
69. What is the molecular mass of thiamine hydrobromide equivalent at it’s quantitative
determination by acidimetry in non-aqueous medium according to SPhU?
A. М.m.
B. *М.m./2
C. М.m./4
D. М.m./8
E. 2 М.m.
70. Choose medical form of thiamine hydrochloride:
A. Powder
B. Ointment
C. Aerosol
D. *Tablets
E. Suppositories
71. Folic acid by its chemical structure belongs to vitamins derivatives of:
A. Purine
B. Piperidine
C. Pyridine
D. *Pterin
E. Pyrazole
72. What reagents can be used to identify thiamine hydrochloride?
A. *K3[Fe(CN)6], NaOH, butyl alcohol
B. AgNO3, HNO3, NH4OH
C. NaNO3, HCl, -naphthol alkaline solution
D. K2Cr2O7, chloroform
E. Sodium nitroprusside, KOH
73. Thiamine hydrobromihe is used in medical practice as?
A. Antiseptic
B. Antispasmodic
C. For the treatment of the urethra dysfunction
D. *For the treatment of nervous system diseases
E. For the diatheses treatment
74. Choose medical form of cocarboxylase?
A. *Powder for parenteral insertion
B. Powdering
C. Powder for per oral insertion
D. Tablets
E. Injection solutions
75. Assay of the folic acid according to SPhU is conducted by the following method:
A. Acidimetry in non-aqueous solution
B. Liquid chromatography
C. *Photocolorimetry
D. Fluorimetry
E. Alkalimetry in non-aqueous solution
76. Cyanocobalamin is a vitamin preparation, in the medical practice it is used as vitamin:
A. В5
B. В2
C. В6
D. В1
E. *В12
77. There are two heterocycles in the cocarboxylase molecule:
A. Pyrimidine, pyrrolidine
B. Thiazole, thiazilidine
C. *Pyrimidine, thiazole
D. Thyazole, pyridine
E. Pyridine, piperidine
78. The main structural parts of vitamin В12 molecule are:
A. *5,6-dimethylbenzimidazole, purine
B. Purine, corrine
C. Corrine, 5,6-dimethylbenzimidazole
D. Tropine, triazole
E. Triazole, purine
79. What medical drug has the following structural formula?
CH2OH
H
OH
O
O
OH
OH
A. Nicotinic acid
B. *Ascorbic acid
C. Ergocalciferol
D. Pantothenic acid
E. Pangamic acid
80. What medical drug has the following structural formula?
A.
B.
C.
D.
Calcium lactate
Calcium citrate
*Calcium pangamate
Calcium pantothenate
E. Calcium gluconate
81. What medical drug has the following structural formula?
A. *Calcium pantothenate
B. Calcium lactate
C. Calcium citrate
D. Calcium pangamate
E. Calcium gluconate
82. What medical drug has the following structural formula?
A. Rutin
B. Tocopherol acetate
C. Ergocalciferol
D. Cianocobalamin
E. *Retinol acetate
83. What medical drug has the following structural formula?
A. Rutin
B. Tocopherol acetate
C. Cholecalciferol
D. *Ergocalciferol
E. Retinol acetate
84. What medical drug has the following structural formula?
A. *Cholecalciferol
B. Rutin
C. Tocopherol acetate
D. Ergocalciferol
E. Retinol acetate
85. What medical drug has the following structural formula?
O
CH3
SO3Na * 3 H2O
O
A. Nicotinic acid
B. *Vikasol
C. Rutin
D. Tocopherol
E. Pyridoxine
86. What medical drug has the following structural formula?
A. Rutin
B. Vikasol
C. *Tocopherol acetate
D. Ergocalciferol
E. Retinol acetate
87. What medical drug has the following structural formula?
A. *Rutine
B. Vikasol
C. Tocopherol acetate
D. Ergocalciferol
E. Retinol acetate
88. What medical drug has the following structural formula?
N
COOH
A. Rutin
B. Tocopherol acetate
C. Vikasol
D. Ascorbic acid
E. *Nicotinic acid
89. What medical drug has the following structural formula?
A. Rutin
B. Tocopherol acetate
C. Nicotinic acid
D. *Nicotinamide
E. Vikasol
90. What medical drug has the following structural formula?
A. *Pyridoxine hydrochloride
B. Rutin
C. Tocopherol acetate
D. Thiamine hydrochloride
E. Nicotinamide
91. What medical drug has the following structural formula?
A. Pyridoxine hydrochloride
B. *Thiamine hydrochloride
C. Riboflavin
D. Cianocobalamin
E. Cocarboxylase
92. What medical drug has the following structural formula?
A. Pyridoxine hydrochloride
B. Thiamine hydrochloride
C. *Cocarboxylase
D. Riboflavin
E. Cianocobalamin
93. What medical drug has the following structural formula?
A. *Riboflavin
B. Pyridoxine hydrochloride
C. Thiamine hydrochloride
D. Cocarboxylase
E. Folic acid
94. What medical drug has the following structural formula?
A. Riboflavin
B. Cocarboxylase
C. Cianocobalamin
D. Thiamine hydrochloride
E. *Folic acid
95. Steroid cycle in the molecules of cardiac glycosides is revealed by the reaction of:
A. *Lieberman - Burhardt
B. Legal
C. Raymond
D. Baljet
E. Keller-Kilian
96. Pentamerous lactone cycle in the molecules of cardiac glycosides is revealed by the reaction
of:
A. Raymond
B. *Legal
C. Lieberman - Burhardt
D. Keller-Kilian
E. Baljet
97. Source of obtaining cardiac glycosides are different types of:
A. Belladonna
B. Poppy
C. *Digitalis
D. Hemp
E. Ephedrine
98. Quantitative determination of cardiac glycosides according to the procedures DF X is
carried out by the method of:
A. Photocolorimetry
B. Acidimetry
C. Infrared spectroscopy
D. Alkalimetry
E. *Biological method
99. What monosaccharide is nonspecific for cardiac glycosides?
A.
B.
C.
D.
E.
Digitoxose
D-cymarose
L-rhamnose
Oleandroze
*Fructose
100.
The aglycone structure of the cardiac glycosides, which are called cardenolides, is
formed of such lactone cycle:
A. *Pentamerous
B. 6-membered
C. Heptatomic
D. 4-membered
E. Octatomic
101.
Bufadienolides are the part of:
A. Digitalis
B. *Hellebore
C. Adonis
D. Lily of the valley
E. Strophanthus
102.
2-deoxysaccharides in the molecule of cardiac glycosides is revealed by the reaction
of:
A. Legalov
B. *Pezets
C. Raymond
D. Baleta
E. Lieberman - Burhardt
103.
Which of the saccharides is included in the structure of the ouabain molecule?
A. Lactose
B. Digitoxose
C. D-Cymarose
D. *L-Rhamnose
E. D-Oleandroze
104.
Aglycone in the celanidum molecule is :
A. Strofantidine
B. Gitoxigenin
C. Digitoxigenin
D. *Digoxigenine
E. Oleandrogenine
105.
The bearer of the biological activity in the cardiac glycosides is:
A. Saccharic part
B. Pentamerous lactone cycle
C. *Aglycone
D. Radical in the position of the 10th aglycone
E. OH-group in the position of the 14th aglycone
106.
Six-membered lactone cycle in the molecule of cardiac glycosides may be detected
with a solution:
A. FeCl3
B. H2SO4
C. AlCl3
D. *SbCl3
E. CuSO4
107.
Steroid cycle in the molecules of cardiac glycosides is revealed by the reaction of:
A. *Rosenheim
B.
C.
D.
E.
Legalov
Keller-Kilian
Pezets
Balet
108.
Pentamerous lactone cycle in the molecules of cardiac glycosides is revealed by the
reaction of:
A. Lieberman-Burhardt
B. *Raymond
C. Rosenheim
D. Keller-Kilian
E. Pezets
109.
2-deoxysaccharides in the molecule of cardiac glycosides is revealed by the reaction
of:
A. Legalov
B. Raymond
C. *Pezets
D. Rosenheim
E. Lieberman-Burhardt
110.
1According to their chemical structure cardiac glycosides belong to:
A. Heterocyclic carboxylic acids
B. Aromatic amines
C. *Esters
D. Ethers
E. Polyhydric alcohols
111.
Cardiac glycosides are extracted from various plants, one of which is:
A. Belladonna
B. Snakewood (Rauvolfia serpentina)
C. Senecio platyphyllos
D. *Spring Adonis(Adonis vernalis)
E. Henbane (Hyoscyamus niger L)
112.
Which of the saccharides does not belong to the cardiac glycosides structure?
A. *Lactose
B. Digitoxose
C. D-cymarose
D. L-rhamnose
E. D-oleandroze
113.
Bufadienolidy are the part of:
A. Digitalis
B. Adonis
C. Lily of the valley
D. *Sea onion (Urginea maritima)
E. Strophanthus
114.
Saccharic component, which is attached at position 3 to the cardiac glycoside
aglycone, affects:
A. Medical product form
B. *The duration of drug action
C. Directions for use
D. Specific action of cardiac glycosides
E. Side effects
115.
Cardiac glycosides of the cardenolide group include in their molecule:
A. Steroid cycle
B. Double bond between C atoms
C. Triple bond between C atoms
D. Six-membered lactone cycle
E. *Pentamerous lactone cycle
116.
Quantitative determination of cardiac glycosides is carried out by the method of:
A. Photocolorimetry
B. Acidimetry
C. *UV- spectroscopy
D. Alkalimetry
E. Precipitation titration
117.
Cardiac glycosides genins are derived from:
A. Cyclohexane
B. Cholesterol
C. *Cyclopentaneperhydrophenanthrene
D. Adrostan
E. Ergocalciferol
118.
In the digitoxin molecule the aglycone is:
A. Strophantidine
B. Gitoksigenine
C. *Digitoxigenin
D. Digoxigenine
E. Oleandrogenine
119.
Cardiac glycosides aglycones are the derivatives of:
A. Cholesterol
B. Steranes
C. *Cyclopentaneperhydrophenanthrene
D. Androstane
E. Pregnenolone
120.
Pentamerous lactone cycle in the cardiac glycosides molecule is revealed by the
reaction of:
A. *Raymond
B. Sakagush
C. Lugol
D. Ovchinnikov
E. Rosenkheim
121.
Steroid cycle in the structure of cardiac glycosides is revealed by the reaction of:
A. Legalov
B. Raymond
C. Balet
D. *Lieberman-Burhardt
E. Keller-Kilian
122.
Aglycone in the digoxin molecule is:
A. Strophantidine
B. Gitoksigenine
C. Digitoxigenin
D. *Digoxigenine
E. Oleandrogenine
123.
Konvalyatoksin the medical product of cardiac glycosides is extracted from such
plant:
A. Strophanthus Combe
B. Strophanthus gratus
C. *Convallaria majalis
D. Erysimum diffuse
E. Digitalis lanata
124.
Cardenolides are identified by the maximum absorption at  = 220 nm, comparing
with the standard sample of preparation. Specify which physicochemical method is used
then
A. Refractometry
B. Fluorometry
C. Polarimetry
D. *Spectrophotometry
E. Polarography
125.
Saccharid part in the cardiac glycosides molecules may be detected after acid
hydrolysis by the reaction of:
A. *Formation of silver mirror
B. Dragendorf reagent
C. Lieberman-Burhardt reagent
D. Pezets reagent
E. Schiff
126.
The drug ouabain is also known as:
A. *Strophanthin-G
B. Strophanthin-K
C. Korglikon
D. Adonisid
E. Kardiovalen
127.
Saccharic part of the digitalis secondary glycosides consists of three molecules:
A. D-Glucose
B. *Digitoxose
C. D-Cymarose
D. L-Rhamnose
E. D-Oleandroze
128.
By the chemical structure glucose is related to:
A. Polysaccharides
B. Disaccharides
C. *Monosaccharides
D. Ketopentose
E. Aldopentose
129.
Indicate starch formula:
A. C12H22O11
B. C5H10O5
C. *(C6H10O5)n
D. C6H14O7
E. C6H12O7
130.
Sucrose aqueous solution heating generates:
A. Beet sugar
B. Cane sugar
C. Lactose
D. *Invert sugar
E. Tautorotation sugar
131.
What analytical reaction effect is observed during the interaction of glucose with the
Feling reagent?
A. Crimson-violet formations
B. A yellow sediment
C. Formations of violet colour
D. *Formations of red sediment
132.
133.
134.
135.
136.
137.
138.
139.
140.
E. CO2 bubbles separation with the subsequent identification
One of the methods of glucose quantitative determination is the method of:
A. Acidimetry
B. Alkalimetry
C. *Iodinometry
D. Permanganatometry
E. Complexometry
Which of the following saccharides relates to non-restorable glycosacchara:
A. Glucose
B. Lactose
C. Maltose
D. *Sucrose
E. Fructose
Which molecule property results the optical activity of the glucose solution?
A. The tautomery characteristic
B. Changing of the solution refraction angle
C. *The ability to rotate the polarized light plane as it passes through the solution
D. Inversion phenomenon
E. Changes in the EMF solution
By its chemical structure the starch belongs to the group of:
A. Disaccharides
B. Monosaccharides
C. Proteoglycans
D. *Polysaccharides
E. Peptidoglycans
What chemical compound when it’s heated forms caramel?
A. Glucose
B. Lactose
C. Starch
D. *Sucrose
E. Amylose
In medical practice sucrose is used:
A. For the treatment of shock
B. For trituration manufacturing
C. *For the manufacture of syrups
D. For collapse
E. For the treatment of radiation sickness
Which hydrocarbon belongs to the hexose class?
A. Starch
B. D-Ribose
C. Sucrose
D. Lactose
E. *D-glucose
Indicate the sucrose formula:
A. C5H10O5
B. C5H12O5
C. C6H12O6
D. (C6H10O5)n
E. *C12H22O11
What monosaccharide is in the lactose molecule?
A. D-(+)-mannose
B. D-(-)-ribose
C. *D-galactose
D. D-fructose
E. L-fucose
141.
What glucose properties determine the reaction with ammonia solution of silver
nitrate:
A. The ability to rotate the polarization plane of polarized light
B. *Regenerative
C. Oxidative
D. The ability to polymerization
E. The ability to absorb light in the UV-area spectrum
142.
Pharmacist-analyst conducts quantitative determination of glucose by the
iodinometry method. What is the molar mass of equivalent?
A. 1/3 М.m.
B. *¼ М.m.
C. ½ М. m.
D. М.m.
E. 1,5 M.m.
143.
What of the following succharides is characterized by the inversion phenomenon?
A. Maltose
B. Cellobiose
C. Lactose
D. *Sucrose
E. Glucose
144.
The interaction of glucose with mineral acids at time of heating forms:
A. Furfural
B. Acetone
C. Benzol
D. *Methylolfurfural
E. Toluene
145.
Determine the type of reaction which is used for the glucose identification:
A. Recovery
B. Polymerization
C. Polycondensation
D. *Oxidation
E. Expansions
146.
Angle measurement of the 10% glucose solution conversion is carried out by:
A. UV-spectrophotometer
B. Refractometer
C. Infrared spectrophotometer
D. *Polarimeter
E. Photoelectrocolorimeter
147.
Sucrose is used in medical practice:
A. As a means of enveloping
B. To slow down the absorption of drugs
C. For the trituration preparation
D. Antidote to heavy metal poisoning
E. *Auxiliary for the preparation of medicines
148.
Due to its chemical structure glucose belongs to:
A. Aldopentoses
B. Ketopentoses
C. *Aldogeksoses
D. Desoxisaccharides
E. Ketogexoses
149.
Indicate the lactose formula:
A. C5H10O5
B. C5H12O5
C. C6H12O6
D. *C12H22O11
E. (C6H10O5)n
150.
Which monosaccharide is a component of sucrose?
A. alpha-D-galactose
B. Amylose
C. *beta-D-fructose
D. Amylopectin
E. D-digitoxose
151.
In the interaction with which reagent glucose constitutes osasone?
A. Nessler reagent
B. Tollens reagent
C. Phenylhydrazine
D. *Sorrel acid
E. Feling reagent
152.
One of the glucose identification reactions held by rapid analysis method is the
interaction with:
A. Sodium to sodium, weak chloride acid
B. Alkaline beta-naphthol solution
C. Thorium nitrate
D. *Thymol, concentrated sulphate acid
E. Milon basis
153.
With what reagent solution lactose aqueous solution while heated is painted in red?
A. Vanillin
B. Dimethylaminobenzaldehyde
C. Sodium nitroprusside
D. Ammoniac
E. *Resorcin
154.
Glucose is characterized by the phenomenon of:
A. Inversion
B. Dismutation
C. *Polymerization
D. Gelatinization
E. Tautorotation
155.
What glucose molecule fragment conditioned its property to rotate the polarized light
plane?
A. Aldehyde group
B. Alcoholic hydroxyls
C. *Chirality centers
D. Carbon backbone chain
E. Tautomeric groups
156.
One of the lactose identification reactions is the interaction with the reagent of:
A. Marky
B. *Fisher
C. Copper-tartrate
D. Dragendorf
E. Molish
157.
The quantitative content of glucose in solutions for injection is carried out by:
A.
B.
C.
D.
E.
UV-spektoskopy
Refractometry
*Photoelectrocolorimetry
Infared spectroscopy
Potentiometry
158.
On the torpenoid molecule base is the hydrocarbon of:
A. Butene
B. Butadiene
C. *Isoprene
D. Pentene
E. Isopentene
159.
Chemical name of (1RS, 4SR) -1,7,7-Trimethylbicyclic [2,2,1] heptane-2-ol
corresponds to the formula of:
A. Validol
B. Terpinehydrate
C. Sulfocamphocaine
D. Menthol
E. *Camphor
160.
Quantitative determination of validol in accordance with AND is carried out by the
method of:
A. Acidimetry, back titration
B. *Alkalimetry, back titration
C. Photocolorimetry
D. Argentometry after Folgard
E. Argentometry after Fajans
161.
Bromide-ion in bromcamphor after previous mineralization displays the interaction
with:
A. Ironammoniac alum
B. Ammonium thiocyanate
C. Hydroxylamine hydrochloride
D. Sodium hydroxide and zinc dust at the process of heating
E. *Chloramine, chloride acid under chloroform
162.
Molar mass of menthol equivalent at its quantitative determination by the method of
acetylation is:
A. М.m / 8
B. М.m / 4
C. М.m / 2
D. *М.m.
E. М.m / 3
163.
In the interaction of what drug with the concentrated sulfate acid one feels the smell
of terpineol?
A. Camphora
B. *Terpinehydrate
C. Bromcamphor
D. Menthol
E. Validol
164.
What reagent may detect sulfogroup in the sulfocamphoric acid molecules after its
mineralization with a mixture of Na2CO3 and NaNO3?
A. Pb(CH3COO)2
B. Na2CO3
C. KOH
D. Na3PO4
E. *BaCl2
165.
The starting compounds for Validol are:
A. Terpinehydrate, isovaleric acid
B. *Menthol, isovaleric acid
C. Camphor, valeric acid
D. Phenol, isovaleric acid
E. Thymol, valeric acid
166.
Specify the reagents with the help of which one can realize the reaction of menthol
identification:
A. *Dinitrobenzoylchloride, vanillin in concentrated H2SO4
B. Hydroxylamine hydrochloride
C. Benzaldehyde, concentrated H2SO4
D. Ammonium molybdate
E. Isopropylchloride
167.
Medical product corvalol is used to treat:
A. Allergic diseases
B. Sexually transmitted diseases
C. *Neuroses, tachycardia
D. Dermatitis
E. Chronic polyarthritis
168.
Chemical name of 2-Methylbutadiene-1, 3 is:
A. Butene
B. Propene
C. Pentene
D. *Isoprene
E. Isoamylene
169.
Structural formula of camphor corresponds to the following chemical name:
A. N-Menthadione - 1,8 - hydrate
B. 2-Methylbutadiene-1, 3
C. CMethylisopropylcyclohexane
D. (1RS, 2SR, 5RS) - 5-Methyl - 2 - (1 - Methylethyl) Cyclohexanol
E. *(1RS, 4SR) - 1,7,7 - Trimethylbicyclo [2,2,1] heptane-2- ol
170.
At the quantitative determination of validol according to AND by the alkalimetry
method, back titration, the molar mass of its equivalent is:
A. *М.m.
B. М.m / 2
C. М.m / 4
D. М.m / 8
E. 2 М.m.
171.
Specify the components of drug sulfocamphocaine.
A. Sulfocamphoric acid, menthol
B. Sulfocamphoric acid, camphor
C. Sulphate acid, novocaine base
D. *Sulfocamphoric acid, novocaine base
E. Sulfocamphoric acid, bromcamphor
172.
With the help of what reagent one can identify menthol:
A. 2,4 - Dinitrophenylhydrazine
B. 2,4 - Dinitrochlorbenzene
C. *Dinitrobenzoylchloride
D. Hydrazine sulphate
E. Hydroxylamine hydrochloride
173.
To what group of derivative organic compounds belongs terpinehydrate?
A.
B.
C.
D.
E.
Bicyclic terpenoids
Cycloalkanes
Aromatics
Hormones
*Monocyclic terpenoids
174.
What reagent can detect ketogroup in the bromcamphor molecule?
A. Iron (III) chloride
B. *Hydroxylamine hydrochloride
C. Formaldehyde
D. Benzenelsulfochloride
E. Concentrated nitrate acid
175.
What physical constant determinations are used to identify the sulfocamphor acid?
A. Electricity
B. *Melting temperature
C. Boiling temperature
D. Fracture index
E. Light absorption coefficient
176.
L-Camphor is obtained by the method of:
A. V. E. Tishchenko
B. D. M. Mendeleyev
C. *N. V. Vershinin
D. M. M. Zinin
E. O. M. Butlerov
177.
Menthol is a part of such combined preparations:
A. *Pektusin, boromenthol, menovazin
B. Pertusin, bom-benge ointment
C. Pektosol, Lasar dope
D. Dry linctus
E. Validol, gerovital
178.
Monocyclic terpenoids drugs are derived from:
A. Camphene
B. Menthol
C. *Mentane
D. Camphane
E. Camphor
179.
Starting material to obtain menthol by the synthetic method is:
A. Toluene
B. Benzene
C. *m-Cresol
D. Pyrocatechol
E. Pyrogalol
180.
Menthol in validol is identified according to the requirements of the AND by
interaction with:
A. FeCl3 solution
B. *Vanillin solution in concentrated H2SO4
C. Concentrated sulphate acid
D. Hydroxylamine hydrochloride
E. Nesler's reagent
181.
The bromcamphor quantitative determination after previous mineralization
according to the AND requirements is held by the method of argentometry after:
A. Fajans
B. Mor
C. *Folgard
D. Koltgof
E. Fajans-Khodakov
182.
Chemical name of medical product terpinehydrate is:
A. *N-Mentadiol-1 ,8-hydrate
B. (1RS, 2SR, 5RS)-5-Methyl-2-(1-Methylethyl) Cyclohexane
C. (1RS, 4SR) -1,4,7-Trimethylbicyclo [2,2,1] Heptane-2- ol
D. D-(+)-Glucopyranose
E. 4-L-D-Galactosepyranose
183.
182. Two asymmetric carbon atoms in the camphor molecule define its:
A. Easy water solubility
B. The ability to absorb visible light
C. Easy solubility in alcohol
D. *The ability to rotate the plane of polarized light
E. Poor water solubility
184.
What titrant is used in quantitative determination of novocaine in drug
sulfocamfokaine?
A. Potassium permanganate
B. Sodium hydroxide
C. Hydrogen peroxide
D. *Sodium nitrite
E. Cerium sulphate
185.
The constituents of the drug validol are:
A. Camphor, menthol
B. Camphor, menthyl esther of isovaleric acid
C. Menthol, bromcamphor
D. Menthyl esther of isovaleric acid, sulfocamphoric acid
E. *Menthol solution, menthyl esther of isovaleric acid
186.
Which indicator is used to fix the equivalence point in quantifying validol according
to the requirements of the AND?
A. Cerium (IV) sulphate
B. Starch
C. Feroine
D. *Phenolphthalein
E. Methyl red
187.
Validol is used in medical practice for the treatment of:
A. *Stenocardia angina prectoris, neuroses.
B. Diseases of gastrointestinal tract
C. Dermatitis
D. Allergic diseases
E. Epilepsy
188.
Chemical name of 2-Chlor-10-(3'-Dimethylaminopropyl)-Phenothiazine
Hydrochloride is:
A. Trifluoroperazine hydrochloride
B. Promethazine hydrochloride
C. Promazine hydrochloride
D. *Chlorpromazine hydrochloride
E. Perphenazine hydrochloride
189.
Medical product medazepam corresponds to the following chemical name:
A. 7-Brom-1 ,3-Dihydro-5-(o-Chlorophenyl)-1H-1 ,4-Benzodiazepin-2
B. 7-Nitro-1 ,3-Dihydro-5-Phenyl-2H-1 ,4-Benzodiazepin-2
C. 7-Chlor-1 ,3-Dihydro-3-Hydroxy-5-Phenyl-2H-1 ,4-Benzodiazepin-2
D. 7-Chlor-1 ,3-Dihydro-1-Methyl-5-Phenyl-1H-1 ,4-Benzodiazepin-2
E. *7-Chlor-2 ,3-Dihydro-1-Methyl-5-Phenyl-1H-1 ,4-Benzodiazepine
190.
Promethazine hydrochloride corresponds to the following commercial name:
A. Triphtazine
B. Aminazine
C. C.Moracizine hydrochloride
D. *Diprazine
E. Diphenhydramine hydrochloride
191.
What analytical effect one may observe at the interaction of trifluoroperazine
chloride with bromine water:
A. The solution is dark cherry coloured
B. *The solution is crimson
C. The solution is painted in red
D. Formation of white sediment
E. The solution turns light violet
192.
Fusion of phenazepame with sodium hydroxide leads to the destruction of the
molecular bond and isolation of:
A. Chlorine
B. *Ammonia
C. Bromine
D. Urea
E. Methylamine
193.
According to the requirements of AND quantification of trifluoroperazine
hydrochloride substance is held by the method of acidimetry in non-aqueous medium. What
is the equivalent mass of the drug?
A. М.m /8
B. М.m/4
C. 2 М.m
D. М.m
E. *М.m/2
194.
Phenazepame ability to recover is in the basis of quantitative determination of it by
the method of:
A. HPLC
B. Polarimetry
C. *Polarography
D. Potentiometry
E. UV-spectroscopy
195.
The presence of nitrogroup in the nitrozepame structure can be confirmed by the
reaction of its alcoholic solution with :
A. Sodium chloride
B. Acetate acid
C. Sulphate acid
D. Iron (III) chloride
E. *Sodium hydroxide
196.
Commercial name mezapame corresponds to medicinal product:
A. Diazepame
B. Oxazepame
C. Nitrozepame
D. Chlordiazepoxide
E. *Medazepame
197.
One of the methods to quantify drugs, phenothiazine derivatives, is the alkalimetry
method in the aqueous medium. In the presence of what solvent occurs the titration?
A.
B.
C.
D.
E.
Acetone
Benzene
*Chlorophaite
Methyl alcohol
Dimethylformamide (DMF)
198.
Chemical name of 10 - (3'-Dimethylaminopropyl)-Phenothiazine hydrochloride
corresponds to:
A. Chlorpromazine hydrochloride
B. Promethazine hydrochloride
C. Trifluorineperazine hydrochloride
D. *Propazine
E. Ethaperazine
199.
Medicinal product fenazepame corresponds to the following chemical name:
A. *7-Brom-1 ,3-Dihydro-5-(o-Chlorophenyl)-1H-1 ,4-Benzodiazephin-2
B. 7-Nitro-1 ,3-Dihydro-5-Phenyl-2H-1 ,4-Benzodiazepin-2
C. 7-Chloro-1 ,3-Dihydro-3-Hydroxy-5-Phenyl-2H-1 ,4-Benzodiazepin-2
D. 7-Chloro-1 ,3-Dihydro-1-Methyl-5-Phenyl-1H-1 ,4-Benzodiazepin-2
E. 7-Chloro-2 ,3-Dihydro-1-Methyl-5-Phenyl-1H-1 ,4-Benzodiazepine
200.
Commercial name of trifluorineperazine hydrochloride is:
A. Aminazine
B. Diprazine
C. Ftorafur
D. Ftoracil
E. *Triphtazine
201.
Which of the following compounds is the source for the chlorpromazine synthesis?
A. N-Nitrophenol
B. Anisidine
C. 2,4-Dinitrochlorobenzene
D. *2-Chlorphenothiazine
E. Chlorobenzene
202.
Specific reaction after pyrolysis of benzodiazepine derivatives is the formation of the
alloy coloured:
A. *Green
B. Violet
C. Red
D. Blue
E. Black
203.
According to the requirements of GFU quantification of promethazine hydrochloride
is carried out by the alkalimetry method in mixture of alcohol and 0.01 M of chloride acid
solution. Which method fixes endpoint of equivalence?
A. Polarimetry
B. Ion exchange chromatography
C. UV-spectrophotometry
D. *Potentiometry
E. Visual assessment
204.
What is the molecular mass of diazepame equivalent in the quantitative
determination of it by the acidimetry method in non-aqueous medium:
A. 1/4 М m
B. 2 М m
C. 1/5 М m
D. 1/2 М m
E. *М m
205.
Bromide ions are defined in the solution obtained after boiling fenazepame with a
sodium hydroxide solution, by the following reagents:
A. Argentum chloride, nitrate acid
B. Acetate acid, discolored fuchsin
C. Copper sulphate, sulphate acid
D. Iron (III) chloride, chloride acid
E. *Chloride acid, chloramine, chloroform
206.
Commercial name of elenium corresponds to the medicinal product:
A. Diazepame
B. Oxazepame
C. *Chlordiazepoxide
D. Nitrazepame
E. Medazepame
207.
Medicines, benzodiazepine derivatives, are used in medical practice as:
A. Anaesthetic
B. Narcotic analgesics
C. *Tranquilizers
D. Non steroidal anti-inflammatory drugs (NSAIDs)
E. Non-narcotic analgesics
208.
Chemical name of (2RS)-N, N-Dimethyl-1-(10H-Phenothiazine-10-ol) Propane-2Amine Hydrochloride сorresponds to:
A. Chlorpromazine hydrochloride
B. Trifluorineperazine hydrochloride
C. Ethaperazine
D. Ethmozine
E. *Promethazine hydrochloride
209.
Medical product chlordiazepoxide corresponds to the following chemical name:
A. *7-Chloro-2-Methylamino-5-Phenyl-3H-1 ,4-Benzodiazepin-4-Oxide
B. 7-Nitro-1 ,3-Dihydro-5-Phenyl-2H-1 ,4-Benzodiazepin-2
C. 7-Chloro-1 ,3-Dihydro-3-Hydroxy-5-Phenyl-2H-1 ,4-Benzodiazepin-2
D. 7-Chloro-1 ,3-Dihydro-1-Methyl-5-Phenyl-1H-1 ,4-Benzodiazepin-2
E. 7-chloro-2 ,3-dihydro-1-methyl-5-phenyl-1H-1 ,4-benzodiazepine
210.
Commercial name of chlorpromazine hydrochloride is:
A. Ethmozine
B. Ethaperazine
C. *Chlorpromazine
D. Promethazine
E. Chlorpropamide
211.
What properties of drugs, phenothiazine derivatives, are used to identify them?
A. Restoration ability
B. Hydrogenation ability
C. Dehydrogenation ability
D. Polymerization ability
E. *Oxidation ability
212.
211. Positive reaction of drugs, benzodiazepine derivatives, with general alkaloid
sedimentation reagents determines availability of such elements in their structure:
A. Nitrogen atom in position 1
B. *Nitrogen atom in position 4
C. Substitute in position 7
D. Benzene nucleus
E. Lactam group
213.
What method is used to quantify Nitrogen after sulphate P acid mineralization in the
molecules of fenthiazine derivatives drugs?
A. Sanger-Black
B. Bugo-Thiele
C. Marsh
D. *Kjeldal
E. Vitali-Moren
214.
What is the molecular mass of the oxazepam equivalent in the quantitative
determination of it by the acidimetry method in non-aqueous medium:
A. *М m
B. 1/4 М m
C. 2 М m
D. 1/5 М m
E. 1/2 М m
215.
Bromide ions are determined in the solution obtained after boiling fenazepame with a
sodium hydroxide solution,by the following reagents:
A. Silver chloride, nitrate acid
B. *Lead (IV) oxide, acetate acid, discolored fuchsin
C. Copper sulphate, sulphate acid
D. Iron (III) chloride, chloride acid
E. Iodine, chloroform
216.
Commercial name of chlozepide is:
A. Diazepame
B. Oxazepame
C. Nitrazepame
D. *Chlordiazepoxide
E. Medazepame
217.
Nitrogroup in the nitrazepame structure may be confirmed by the reaction of an
alcohol solution with:
A. Sodium chloride
B. Acetate acid
C. Sulphate acid
D. Iron (III) chloride
E. *Sodium hydroxide
218.
What medical product corresponds to the structural formula?
O
O
CH3
H
CH3
H
H
CH3
H
O
O
CH3
O
O
CH3
O
O
OH
OH
A. Digoxin
OH
OH
H
OH
B.
C.
D.
E.
219.
*Digitoxin
Ouabain
Convallatoxin
Celanidum
What medical product corresponds to the structural formula?
O
O
OH
H
CH3
H
CH3
H
H
CH3
OH
H
O
O
H
CH3
O
O
OH
CH3
O
O
OH
OH
OH
A.
B.
C.
D.
E.
220.
Ouabain
Digitoxin
*Digoxin
Convallatoxin
Celanidum
What medical product corresponds to the structural formula?
O
O
H
HO
HO
H
H
H
H
OH
OH
O
O
OH
A.
B.
C.
D.
E.
H
OH
* 8 H2O
CH3
221.
CH3
HO
OH
*Ouabain
Digitoxin
Digoxin
Convallatoxin
Celanidum
What medical product corresponds to the structural formula?
O
O
CH3
H
O
C
H
H
OH
OH
O
O
OH
CH3
OH
A.
B.
C.
D.
E.
222.
OH
Ouabain
Digitoxin
Digoxin
*Convallatoxin
Celanidum
What medical product corresponds to the structural formula?
O
O
OH
CH3
CH3
H
H
OH
CH3
O
O
CH3
O
OH
CH3
O
OH
CH2OH
O
OCOCH3
HO
OH
OH
A.
B.
C.
D.
E.
223.
Ouabain
Digitoxin
Digoxin
Convallatoxin
*Celanidum
What medical product corresponds to the structural formula?
CH2OH
O
H
H
OH
H
H
OH
OH
H
A.
B.
C.
D.
E.
224.
OH
Lactose
Galactose
*Glucose
Sucrose
Rhamnose
What medical product corresponds to the structural formula?
CH2OH
O
OH
H
OH
H
H
OH
H
H
A.
B.
C.
D.
E.
225.
OH
D-glucose
Lactose
Digitoxose
*D-galactose
Sucrose
What medical product corresponds to the structural formula?
H
CH2OH
O
OH
H
OH
A.
B.
C.
D.
E.
226.
H
OH
H
H
H
H
OH
O
H
H
OH
H
O
CH2OH
OH
Glucose
Galactose
Pulp
Sucrose
*Lactose
What medical product corresponds to the structural formula?
CH2OH
O
H
H
OH
H
CH2OH
H
H
O
H
OH
OH
H
O
OH
H
A. Glucose
B. Galactose
OH
CH2OH
227.
C. Pulp
D. Lactose
E. *Sucrose
What medical product corresponds to the structural formula?
NH2 * HCl
A.
B.
C.
D.
E.
228.
Rimantadine
*Midantan
Glyudantan
Validol
Tropatsin (Diphenyltropine)
What medical product corresponds to the structural formula?
COOH
NH O
H
A.
B.
C.
D.
E.
229.
H
H
OH
OH
H
H
OH
Rimantadine
Midantan
*Glyudantan
Validol
Tropatsin(Diphenyltropine)
What medical product corresponds to the structural formula?
H
C
CH3 * HCl
NH2
A.
B.
C.
D.
E.
230.
*Rimantadine
Midantan
Glyudantan
Validol
Tropatsin(Diphenyltropine)
What medical product corresponds to the structural formula?
CH3
OH
CH
H 3C
A.
B.
C.
D.
Camphor
Midantan
Terpingidrat
Validol
CH3
231.
E. *Menthol
What medical product corresponds to the structural formula?
CH3
CH3
+
O
OH
O
CH
H3C
A.
B.
C.
D.
E.
232.
CH
CH3
H3C
C
CH3
C
H2
CH
CH3
CH3
Camphor
Medantan
Terpingidrat
*Validol
Tropatsin(Diphenyltropine)
What medical product corresponds to the structural formula?
H 3C
OH
* H2O
H 3C
A.
B.
C.
D.
E.
233.
CH3
OH
*Terpingidrat
Medantan
Glyudantan
Validol
Tropatsin(Diphenyltropine)
What medical product corresponds to the structural formula?
CH3
O
H3 C
A.
B.
C.
D.
E.
234.
CH3
Validol
Midantan
*Camphor
Menthol
Tropatsin(Diphenyltropine)
What medical product corresponds to the structural formula?
CH3
O
H3C
CH3
Br
A.
B.
C.
D.
E.
235.
Sulfokamfokain
*Bromcamfora
Validol
Midantan
Boromentol
What medical product corresponds to the structural formula?
H2C
SO2OH
O
H3C
A.
B.
C.
D.
E.
236.
CH3
* H2O
Terpingidrat
Sulfokamfokain
*Sulfocamforic acid
Validol
Boromentol
What medical product corresponds to the structural formula?
S
* HCl
N
Cl
H2C
C
H2
C
H2
N
CH3
CH3
A.
B.
C.
D.
E.
237.
Chlordiazepoxide
*Chlorpromazine hydrochloride
Promethazine hydrochloride
Perphenazine hydrochloride
Moracizine hydrochloride
What medical product corresponds to the structural formula?
S
* HCl
N
H 2C
H
C
N
CH3
CH3 CH3
A.
B.
C.
D.
E.
238.
Promazin hydrochloride
Chlorpromazine hydrochloride
*Promethazine hydrochloride
Perphenazine hydrochloride
Moracizine hydrochloride
What medical product corresponds to the structural formula?
S
* HCl
N
H2C
C
H2
C
H2
N
CH3
CH3
A.
B.
C.
D.
E.
239.
*Promazine hydrochloride
Chlorpromazine hydrochloride
Promethazine hydrochloride
Perphenazine hydrochloride
Moracizine hydrochloride
What medical product corresponds to the structural formula?
S
* 2 HCl
N
Cl
(CH2)3
A.
B.
C.
D.
E.
240.
N
N
(CH2)2OH
Promazine hydrochloride
Chlorpromazine hydrochloride
Promethazine hydrochloride
*Perphenazine hydrochloride
Moracizine hydrochloride
What medical product corresponds to the structural formula?
S
* 2HCl
N
CF3
(CH2)3
A.
B.
C.
D.
E.
241.
N
N
CH3
Promethazine hydrochloride
Perphenazine hydrochloride
Moracizine hydrochloride
*Triftorperazine hydrochloride
Chlorpromazine hydrochloride
What medical product corresponds to the structural formula?
S
N
H
N
O
A.
B.
C.
D.
E.
C
Promethazine hydrochloride
Perphenazine hydrochloride
Chlorpromazine hydrochloride
*Moracizine hydrochloride
Levomepromazine
(CH2)2
N
O
* HCl
C
OC2H5
O
242.
What medical product corresponds to the structural formula?
S
* HCl
N
H 2C
OCH3
CH3
H
C
C
H2
N
CH3
CH3
A.
B.
C.
D.
E.
243.
Promethazine hydrochloride
Perphenazine hydrochloride
Chlorpromazine hydrochloride
*Levomepromazine
Chlordiazepoxide
What medical product corresponds to the structural formula?
S
O
NH
C
OC2H5
N
C2H5
O
A.
B.
C.
D.
E.
244.
C
C
H2
C
H2
* HCl
N
C2H5
*Etatsizin
Etaperazin
Elenium
Chlorpromazine
Diazepam
What medical product corresponds to the structural formula?
O
H
N
N
Br
Cl
A.
B.
C.
D.
E.
245.
Diazepam
Aminazine
*Phenazepam
Oxazepam
Etatsizin
What medical product corresponds to the structural formula?
O
H
N
O 2N
N
A.
B.
C.
D.
E.
246.
Diazepam
Phenazepam
*Nitrazepam
Propazin
Aminazine
What medical product corresponds to the structural formula?
O
H
N
OH
N
Cl
A.
B.
C.
D.
E.
247.
Diazepam
Elenium
*Oxazepam
Phenazepam
Aminazine
What medical product corresponds to the structural formula?
CH3
O
N
N
Cl
A.
B.
C.
D.
E.
248.
Phenazepam
Radedorm
*Diazepam
Oxazepam
Aminazine
What medical product corresponds to the structural formula?
CH3
N
Cl
A. Diazepam
B. Phenazepame
C. *Mezapam
N
249.
D. Oxazepam
E. Nitrazepam
What medical product corresponds to the structural formula?
HN
CH3
N
Cl
N
O
A.
B.
C.
D.
E.
Nitrazepam
Propazin
*Chlordiazepoxid
Diazepam
Aminazine
250.
To the medical drugs of the alkalods’ group with exocyclic nitrogen atom:
A. Atropine sulfate, quinine hydrochloride
B. Scopolamine hydrobromide, pachicarpine hydroiodide
C. *Ephedrine hydrochloride, spherophysine benzoate
D. Morphine hydrochloride, codeine phosphate
E. Strychnine nitrate, papaverine hydrochloride
251.
Medical drug pachicarpine hydroiodide according to its chemical structure belongs to
the derivatives of:
A. Tropane
B. Purine
C. Indole
D. Imidazole
E. *Quinolysine
252.
Determine the molecular mass of the ephedrine hydrochloride equivalent at its assay
by acidimetry in non-aqueous environment:
A. 1/4 М.m.
B. 2 М.m.
C. *М.m.
D. 1/2 М.m.
E. 1/5 М.m.
253.
Platyphylline is extracted from the roots and grass of:
A. Cytisus laburnum
B. Thermopsis lanceolata
C. Sophora pachycarpa
D. *Senecio plathyphyllus
E. Rauwolfia serpentina Benth
254.
What reagent is proposed in SPhU to determine alkaloids?
A. Marcy
B. Erdman
C. *Dragendorff
D. Frede
E. Wagner
255.
What reaction can be used to determine guanine residue in spherophysine molecule?
A. Heating with bromine water
B.
C.
D.
E.
Heating with sulfate acid
Vitali-Morin
*Heating with sodium hydroxide
With phenolphthalein
256.
Assay of pilocarpine hydrochloride is conducted according to the AND requirements
by the following method:
A. Gravimetry
B. Comlexonometry
C. Nitritometry
D. Acidimetry in aqueous environment
E. *Acidimetry in non-aqueous environment
257.
Barium is a specific admixture in the quinine hydrochloride. Barium can be
determined with the solution of:
A. Hydrochloric acid
B. Nitrate acid
C. Sodium hydroxide
D. *Sulfate acid
E. Iodine
258.
Pilocarpine hydrochloride is used in the medical practice as:
A. Anesthetic mean
B. *Cholinomimetic mean
C. Uterine muscular stimulant
D. CNS stimulant
E. Antitussive mean
259.
Iodide-ion in the pachycarpine hydroiodide can be detected with the usage of the
following reagents:
A. *AgNO3, HNO3, NH4OH
B. AgNO3, H2SO4, NH4OH
C. AgNO3, H3PO4, NH4OH
D. K2Cr2O7, H2SO4
E. K2Cr2O7, H2SO4, diphenylcarbazide
260.
To the medical drugs from a group of alkaloids, imidazole derivatives, the following
compound belongs:
A. *Pilocarpine hydrochloride
B. Atropine sulfate
C. Ephedrine hydrochloride
D. Strychnine nitrate
E. Papaverine hydrochloride
261.
The medical drug cytitone according to its chemical structure belongs to the
derivatives of:
A. Tropane
B. Purine
C. Indole
D. Imidazole
E. *Quinolysine
262.
Which of the following drugs is responsible to the chemical name 1–guanidino–4–
(isoamilene–1')–aminobutane dibenzoate?
A. Physostigmine salicylate
B. Caffeine sodium benzoate
C. *Spherophysine benzoate
D. Theobromine
E. Cytisine
263.
Pachicarpine isolated from the grass of:
A. Cytisus laburnum
B. Thermopsis lanceolata
C. *Sophora pachycarpa
D. Senecio plathyphyllus
E. Rauwolfia serpentina Benth
264.
What reagents can be used to identify chloride-ion the quinine hydrochloride
molecule?
A. *AgNO3, HNO3, NH4OH
B. AgNO3, H2SO4, NH4OH
C. AgNO3, H3PO4, NH4OH
D. K2CrO4, H2SO4
E. K2Cr2O7, H2SO4, chloroform
265.
A characteristic reaction for pilocarpine hydrochloride is a formation of:
A. Shiff bases
B. *Above chromic acids
C. Azo-dye
D. Peroxide compounds
E. Iodoform
266.
Determine the molecular mass of the quinine hydrochloride equivalent at its assay by
bromatometry:
A. 1/4 М. m.
B. 2 М. m.
C. М. m.
D. *1/2 М. m.
E. 1/5 М. m.
267.
Senecephylline admixture in the platyphylline hydrotartrate can be determined by
the adding of the following solution:
A. Hydrochloric acid
B. Nitrate acid
C. Sodium hydroxide
D. Sulfate acid
E. *Ammonia
268.
Ephedrine hydrochloride is used in the medical practice as:
A. CNS stimulant
B. Analgesic mean
C. Mydriatic mean
D. Local anesthetic mean
E. *Vessels narrow, broncho-spreading
269.
Bouchard reagent is a general precipitate reagent. It includes:
A. *Sol. I2 in КI
B. HgI2 + 2KI↔K2[HgI4]
C. BI3+KI↔K[BI4]
D. Sol. CdI2 in KI
E. 5 % tannin solution
270.
To the medical drugs from a group of alkaloids, pyrrolizidine derivatives, the
following compound belong:
A. Pilocarpine hydrochloride
B. Atropine sulfate
C. *Platyphylline hydrotartrate
D. Strychnine nitrate
E. Papaverine hydrochloride
271.
Assay of cytisine is conducted according to the AND requirements by the following
method:
A. Argentometry by Folgard method
B. Argentometry be Mor’s method
C. *Acidimetry in aqueous environment
D. Gravimetry
E. Iodometry
272.
Marcy reagent is a general alkaloid color reagent. It includes:
A. Concentrated sulfate acid
B. Concentrated sulfate and concentrated nitrate acid
C. Ammonium molybdate in concentrated sulfate acid
D. *formaldehyde solution in concentrated sulfate acid
E. p-Dimethylaminobenzaldehyde in concentrated sulfate acid
273.
Ephedrine is obtained from:
A. Belladonna
B. *Ephedra
C. Vanillin
D. Benzene
E. Rauwolfia
274.
Which of the following preparations does give taleyoquine test?
A. Atropine sulfate
B. *Quinine sulfate
C. Ephedrine hydrochloride
D. Cytisine
E. Codeine
275.
For the lactone cycle identification in the pilocarpine hydrochloride molecule the
following reaction can be used:
A. Vitali-Morin
B. Taleyoquine formation
C. *Legal
D. Lughole
E. Bouchard
276.
Determine the molecular mass of the spherophysine benzoate equivalent at its assay
by bromatometry:
A. 1/4 М. m
B. 2 М. m
C. *1/2 М. m
D. М. m
E. 1/5 М. m
277.
What reagents can be used to identify iodide-ion the pachycarpine hydroiodide
molecule?
A. *AgNO3, HNO3, NH4OH
B. AgNO3, H2SO4, NH4OH
C. AgNO3, H3PO4, NH4OH
D. K2Cr2O7, H2SO4
E. K2Cr2O7, H2SO4, diphenylcarbazide
278.
Spherophysine benzoate is used in the medical practice as:
A. Expectorant mean
B. Antitussive mean
C. Antibacterial mean
D. *Hypotensive mean
E. Hypoglycemic mean
279.
Medical drug cytitone is:
A. a 0,5 % cytisine aqueous solution
B. a 1 % cytisine alcoholic solution
C. *a 0,15 % cytisine aqueous solution
D. a 2 % solution of nicotinic acid
E. a 40 % formaldehyde solution
280.
Which of the following preparations has chemical name tropinic ester of
diphenylacetic acid hydrochloride?
A. Codeine
B. Caffeine
C. Proserin
D. *Tropacine
E. Cytisine
281.
Determine the molecular mass of the atropine sulfate equivalent at its assay by
alkalimetry in alcohol-chloroform environment:
A. 1/4 М. m
B. 2 М. m
C. М. m
D. *1/2 М. m
E. 1/5 М. m
282.
What medical drug does include papaverine hydrochloride?
A. No-spa
B. Analgin
C. Adelphane
D. *Papazol
E. Citramone
283.
Atropine sulfate is used in the medical practice as:
A. Anesthetic mean
B. *Cholinolytic mean
C. Uterine muscular stimulant
D. Emetic mean
E. Antitussive mean
284.
Which of the following preparations has chemical name 3,6 –dioxy–N-methyl-4,5–
epoxymorphinene–7 trihydrate hydrochloride?
A. Codeine phosphate
B. Caffeine monohydrate
C. Cocaine hydrochloride
D. *Morphine hydrochloride
E. Papaverine hydrochloride
285.
What reagents can be used to identify phosphate-ion in the codeine phosphate
molecule?
A. *AgNO3, HNO3
B. AgNO3, H2SO4
C. AgNO3, NH3
D. K2Cr2O7, H2SO4
E. K2Cr2O7, HCl
286.
Assay of apomorphine hydrochloride according to the AND requirements is
conducted by the following method:
A. Gravimetry
B. Complexonometry
C. Nitritometry
D. *Acidimetry in non-aqueous environment
E. Alaklimetry by the substitute
287.
Morphine hydrochloride is used in the medical practice as:
A. Anesthetic mean
B. *Narcotic analgesic mean
C. Uterine muscular stimulant
D. Emetic mean
E. Antitussive mean
288.
To the alkaloids’ group medical drugs, morphinane derivatives, the following
compound belongs:
A. Physostigmine salicylate
B. Strychnine nitrate
C. *Codeine phosphate
D. Ethylmorphine hydrochloride
E. Caffeine monohydrate
289.
What reagents can be used to identify chloride-ion the apomorphine hydrochloride
molecule?
A. *AgNO3, HNO3, NH4OH
B. AgNO3, H2SO4, NH4OH
C. AgNO3, H3PO4, NH4OH
D. K2Cr2O7, H2SO4, chloroform
E. K2Cr2O7, H2SO4, iodine
290.
Assay of atropine sulfate according to the AND requirements is conducted by the
following method:
A. Gravimetry
B. Complexonometry
C. Nitritometry
D. Acidimetry in aqueous environment
E. *Acidimetry in non-aqueous environment
291.
Drotaverine hydrochloride is the chemical name of the following spasmodic mean:
A. Baralgine
B. Papaverine
C. Papazol
D. *No-spa
E. Spasmalgon
292.
Which of the following preparations has chemical name 1–(3',4'–dimethoxybenzyl)–
6,7–dimethoxyisoquinoline hydrochloride:
A. Quinine hydrochloride
B. Ephedrine hydrochloride
C. Cocaine hydrochloride
D. Morphine hydrochloride
E. *Papaverine hydrochloride
293.
Assay of cocaine hydrochloride according to the AND requirements is conducted by
the following method:
A. *Acidimetry in non-aqueous environment
B. Nitritometry
C. Complexonometry
D. Alkalimetry in non-aqueous environment
E. Alkalimetry in alcohol-chloroform environment
294.
What reagent can be used to determine phenol hydroxyl in the morphine
hydrochloride molecule?
A. Sulfanilic acid (diazonium salt)
B. Sodium hydroxide
C. Vanillin solution in glycerin
D. *Iron (III) chloride
E. Hydrogen peroxide
295.
Characteristic reaction for ethylmorphine hydrochloride is formation of:
A. Taleyoquine
B. Murexide
C. *Iodoform
D. Aurine dye
E. Ethylmorphine hydroxamate
296.
Apomorphine hydrochloride is used in the medical practice as:
A. *Emetic mean
B. Narcotic analgesic mean
C. Uterine muscular stimulant
D. Antitussive mean
E. Expectorant mean
297.
Assay of codeine according to the SPhU requirements is conducted by the following
method:
A. Gravimetry
B. Permanganatometry
C. *Acidimetry in non-aqueous environment
D. Nitritometry
E. Acidimetry in aqueous environment
298.
Choose the sours for glaucine hydrochloride obtaining:
A. *Glaucinum flavum
B. Rauwolfia
C. Passiflora incarnata
D. Emetic nut
E. Convallaria majalis
299.
Determine the molecular mass of the morphine hydrochloride equivalent at its assay
by acidimetry in non-aqueous environment:
A. 1/4 М m
B. 2 М m
C. *М m
D. 1/2 М m
E. 1/5 М m
300.
Medical drug atropine sulfate according to its chemical structure belongs to the
derivatives of:
A. *Tropine
B. Purine
C. Indole
D. Imidazole
E. Quinolysine
301.
To the alkaloids’ group medical drugs, morphinane derivatives, the following
compound belongs:
A. Physostigmine salicylate
B. *Morphine hydrochloride
C. Papaverine hydrochloride
D. Apomorphine hydrochloride
E. Caffeine monohydrate
302.
Codeine phosphate in the medical practice is used as:
A. Anesthetic mean
B. Expectorant mean
C. Uterine muscular stimulant
D. Anticholinesterase mean
E. *Antitussive mean
303.
Determine the molecular mass of the apomorphine hydrochloride equivalent at its
assay by acidimetry in non-aqueous environment:
A. 1/4 М m
B. 2 М m
C. *М m
D. 1/2 М m
E. 1/5 М m
304.
To the alkaloids’ group medical drugs, indole derivatives, the following compound
belongs:
A. Pilocarpine hydrochloride
B. *Physostigmine salicylate
C. Platyphylline hydrotartrate
D. Cocaine hydrochloride
E. Papaverine hydrochloride
305.
Proserin in the medical practice is used as:
A. Anesthetic mean
B. Cholinolytic mean
C. Adrenomimetic mean
D. *Anticholinesterase mean
E. Antitussive mean
306.
What salt of strychnine is used as medical drug?
A. Sulfate
B. *Nitrate
C. Hydrobromide
D. Benzoate
E. Phosphate
307.
Reserpine can be allocated from the roots of:
A. Cytisus laburnum
B. Thermopsis lanceolata
C. Sophora pachycarpa
D. Senecio plathyphyllus
E. *Rauwolfia serpentina Benth
308.
What reagent can be used to determine salicylate-ion in the physostigmine salicylate
molecule?
A. Sodium nitroprusside
B. Sodium hydroxyde
C. Vanillin solution in glycerin
D. *Iron (III) chloride
E. Sodium carbonate
309.
Determine molecular mass of the caffeine at its assay by reverse iodometry method:
A. *1/4 М m
B. 2 М m
C. М m
D. 1/2 М m
E. 1/5 М m
310.
What reagent can be used to determine benzoate-ion in the sodium caffeine-benzoate
molecule?
A. Sodium nitroprusside
B. Sodium hydroxyde
C. Vanillin solution in glycerin
D. *Iron (III) chloride
E. Nitric acid
311.
Which of the following preparations has chemical name 1,3,7–trimethylxanthine?
A. Codeine
B. *Caffeine
C. Reserpine
D. Theobromine
E. Proserin
312.
Choose the reaction for theobromine identification:
A. Pellagri
B. Vitali-Morin
C. Taleyoquine test
D. *Murexide sample
E. Periodide formation
313.
Medical drug euphylline according:
A. Morphinane
B. *Purine
C. Indole
D. Aporphine
E. Quinolysine
314.
Physostigmine salicylate in the medical practice is used as:
A. Anesthetic mean
B. Cholinolytic mean
C. Uterine muscular stimulant
D. *Anticholinesterase mean
E. Antitussive mean
315.
To the alkaloids’ group medical drugs, indole derivatives, the following compound
belongs:
A. *Proserine
B. Caffeine
C. Ephedrine
D. Codeine
E. Theobromine
316.
Medical drug strychnine nitrate according to its chemical structure belongs to the
derivatives of:
A. morphinane
B. Purine
C. *Indole
D. Aporphine
E. Quinolysine
317.
Proserin is used in the medical practice in the form of:
A. *Tablets
B. Eyes ointments
C. Eyes drops
D. Ointments
E. Tinctures
318.
Which of the following preparations has chemical name 1,3–dimethylxanthine
monohydrate:
A. Codeine
B. Caffeine
C. Reserpine
D. Theobromine
E. *Theophylline
319.
Pentoxifylline according to its chemical structure belongs to the derivatives of:
A. Caffeine
B. *Theobromine
C. Theophylline
D. Physostigmine
E. Atropine
320.
Medical drug theobromine according to its chemical structure belongs to the
derivatives of:
A. Morphinane
B. *Purine
C. Indole
D. Aporphine
E. Quinine
321.
Choose the reaction for theophylline identification:
A. Pellagri
B. Vitali-Morin
C. Taleyoquine sample
D. *Murexide sample
E. Periodide formation
322.
Physostigmine salicylate is used in the medical practice in the form of:
A. Powder
B. Injection solutions
C. *Eyes drops
D. Creams
E. Vaginal suppositories
323.
Medical drug proserin according to its chemical structure belongs to the derivatives
of:
A. Morphinane
B. Purine
C. *Indole
D. Aporphine
E. Quinine
324.
To the alkaloids’ group medical drugs, indole derivatives, the following compound
belongs:
A. Pilocarpine hydrochloride
B. *Strychnine nitrate
C. Platyphylline hydrotartrate
D. Cocaine hydrochloride
E. Papaverine hydrochloride
325.
Reserpine in the medical practice is used as:
A. Anesthetic mean
B. Cholinolytic mean
C. Uterine muscular stimulant
D. *Hypotensive mean
E. antitussive mean
326.
Which of the following preparations has chemical name 1,3,7–trimethylxanthine:
A. Codeine
B. *Caffeine
C. Reserpine
D. Theobromine
327.
of:
E. Proserin
Medical drug euphylline according to its chemical structure belongs to the derivatives
A.
B.
C.
D.
E.
Morphinane
*Purine
Indole
Aporphine
Quinine
328.
Caffeine in the medical practice is used as:
A. Anesthetic mean
B. Cholinolytic mean
C. *CNS stimulant
D. Uterine muscular stimulant
E. Antitussive mean
329.
Assay of theophylline is conducted according to the AND requirements by the
following method:
A. Gravimetry
B. Complexonometry
C. Nitritometry
D. Acidimetry in aqueous environment
E. *Alaklimetry, titration by the substitute
330.
What medical drug has the following structural formula?
H
C
H
C
CH3
HCl
OH NHCH3
A.
B.
C.
D.
E.
331.
Cytisine
*Ephedrine hydrochloride
Platyphylline hydrotartrate
Pilocarpine hydrochloride
Quinine hydrochloride
What medical drug has the following structural formula?
H3C
NH
CH
H3C
C
H
C
H
A.
B.
C.
D.
E.
332.
C2H5
O
C
H2
C
H2
O
C
H2
C
H2
N
H
C
2 C6H5COOH
NH2
Cytisine
Sodium caffeine-benzoate
Spherophysine salicylate
Pilocarpine hydrochloride
*Spherophysine benzoate
What medical drug has the following structural formula?
C
H2
A.
B.
C.
D.
E.
333.
N
H
N
CH3
HCl
N
Pachicarpine hydroiodide
Ephedrine hydrochloride
Platyphylline hydrotartrate
*Pilocarpine hydrochloride
Quinine hydrochloride
What medical drug has the following structural formula?
CH3 CH3
H3C
C
H
C
C
H2
O
C
C
H
O
C
OH
C
O
O
HO
HOOC
CH2
H
C
C
H
COOH
OH
N
A.
B.
C.
D.
E.
334.
Platyphylline benzoate
Ephedrine hydrochloride
*Platyphylline hydrotartrate
Pilocarpine hydrochloride
Cytisine
What medical drug has the following structural formula 5?
NH
N
O
A.
B.
C.
D.
E.
335.
Platyphylline benzoate
Ephedrine hydrochloride
Platyphylline hydrotartrate
Pilocarpine hydrochloride
*Cytisine
What medical drug has the following structural formula?
N
CH2
HI
N
A.
B.
C.
D.
E.
336.
Pachicarpine hydrochloride
Ephedrine hydrochloride
Platyphylline hydrotartrate
Pilocarpine hydrochloride
*Pachicarpine hydroiodide
What medical drug has the following structural formula?
HC
CH2
HO
CH
H3CO
* H2SO4 * 2H2O
N
A.
B.
C.
D.
E.
337.
N
2
Pachicarpine sulfate
Atropine sulfate
Quinine hydrosulfate
*Quinine sulfate
Quinine hydrochloride
What medical drug has the following structural formula?
HC
CH2
HO
CH
N
H3CO
* HCl *2H 2O
N
A.
B.
C.
D.
E.
338.
Pachicarpine hydrochloride
Ephedrine hydrochloride
Quinine dihydrate
Quinine sulfate
*Quinine hydrochloride
What medical drug has the following structural formula?
HC
CH2
HO
CH
N
H3CO
* 2HCl
N
A.
B.
C.
D.
E.
339.
Pachicarpine hydrochloride
Ephedrine hydrochloride
Quinine dihydrate
*Quinine dihydrochloride
Quinine hydrochloride
What medical drug has the following structural formula?
CH2OH
N
CH3
O
C
CH
C6H5
* H2SO4 * H2O
O
2
A.
B.
C.
D.
E.
340.
Quinine sulfate
*Atropine sulfate
Scopolamine sulfate
Cocaine sulfate
Tropacine
What medical drug has the following structural formula?
CH2OH
O
N
CH3
O
C
CH
C6H5 * HBr * 3 H2O
O
A.
B.
C.
D.
E.
341.
Homatropine hydrobromide
Atropine hydrobromide
*Scopolamine hydrobromide
Cocaine bromide
Tropacine
What medical drug has the following structural formula?
OH
N
CH3
O
C
CH
C6H5 * HBr
O
A.
B.
C.
D.
E.
342.
*Homatropine hydrobromide
Atropine bromide
Scopolamine hydrobromide
Cocaine bromide
Tropacine
What medical drug has the following structural formula?
C6H5
N
CH3
O
C
CH
C6H5 * HCl
O
A.
B.
C.
D.
E.
343.
Homatropine hydrochloride
Morphine hydrochloride
Papaverine hydrochloride
Cocaine hydrochloride
*Tropacine
What medical drug has the following structural formula?
COOCH3
N
CH3
O
C
C6H5 * HCl
O
A.
B.
C.
D.
E.
344.
Homatropine hydrochloride
Morphine hydrochloride
Papaverine hydrochloride
*Cocaine hydrochloride
Tropacine
What medical drug has the following structural formula?
H3CO
N
H3CO
H3CO
CH2 * HCl
H3CO
A.
B.
C.
D.
E.
345.
*Papaverine hydrochloride
Morphine hydrochloride
Drotaverine hydrochloride
Cocaine hydrochloride
Tropacine
What medical drug has the following structural formula?
C2H5O
NH
C2H5O
C2H5O
CH * HCl
C2H5O
A.
B.
C.
D.
E.
346.
Papaverine hydrochloride
Morphine hydrochloride
*Drotaverine hydrochloride
Cocaine hydrochloride
Tropacine
What medical drug has the following structural formula?
HO
* HCl * 3 H2O
O
N
CH3
HO
A.
B.
C.
D.
E.
347.
Papaverine hydrochloride
*Morphine hydrochloride
Drotaverine hydrochloride
Cocaine hydrochloride
Tropacine
What medical drug has the following structural formula?
H3CO
* H2O
O
N
CH3
HO
A.
B.
C.
D.
E.
348.
Caffeine
Morphine
*Codeine
Cocaine
Tropacine
What medical drug has the following structural formula?
C2H5O
O
* HCl * 2 H2O
N
CH3
HO
A. Papaverine hydrochloride
B. Morphine hydrochloride
349.
C. Drotaverine hydrochloride
D. Cocaine hydrochloride
E. *Ethylmorphine hydrochloride
What medical drug has the following structural formula?
HO
HO
* HCl * 3/4 H2O
N
A.
B.
C.
D.
E.
350.
CH3
Papaverine hydrochloride
Morphine hydrochloride
*Apomorphine hydrochloride
Cocaine hydrochloride
Ethylmorphine hydrochloride
What medical drug has the following structural formula?
OCH3
H3CO
* HCl
H3CO
N
CH3
H3CO
A.
B.
C.
D.
E.
351.
Papaverine hydrochloride
Morphine hydrochloride
Apomorphine hydrochloride
*Glaucine hydrochloride
Ethylmorphine hydrochloride
What medical drug has the following structural formula?
CH3
H 3C
N
H
C
O
COOH
O
A.
B.
C.
D.
E.
352.
*
N
N
CH3
CH3
OH
Spherophysine benzoate
*Physostigmine salicylate
Proserin
Resorcinol
Caffeine
What medical drug has the following structural formula?
H3C
+
N
C
O
N
H3C
353.
CH3
CH3
O
A.
B.
C.
D.
E.
CH3
CH3SO4
-
Spherophysine benzoate
Physostigmine salicylate
*Proserin
Resorcinol
Caffeine
What medical drug has the following structural formula?
N
N
O
O
A.
B.
C.
D.
E.
354.
*Strychnine
Physostigmine
Reserpine
Proserin
Theobromine
What medical drug has the following structural formula?
N
H3CO
N
H
OCH3
H3COOC
O
OCH3
C
OCH3
O
OCH3
A.
B.
C.
D.
E.
355.
Strychnine
Diprophylline
Proserin
Theobromine
*Reserpine
What medical drug has the following structural formula?
O
H3C
N
N
N
O
CH3
N
CH3
A. Cocaine
B. Theophylline
C. Theobromine
D. *Caffeine
E. Codeine
What medical drug has the following structural formula?
O
O
356.
C
H3C
N
N
CH3
ONa
*
N
O
A.
B.
C.
D.
E.
357.
N
CH3
*Sodium caffeine-benzoate
Spherophysine benzoate
Codeine
Pentoxifylline
Euphylline
What medical drug has the following structural formula?
O
HN
O
N
N
CH3
N
CH3
A. Tropacine
B. Theophylline
C. *Theobromine
D. Caffeine
E. Codeine
358.
What medical drug has the following structural formula?
O
H3C
N
NH
N
O
N
CH3
A. Tropacine
B. *Theophylline
C. Theobromine
D. Caffeine
E. Codeine
359.
What medical drug has the following structural formula?
O
O
H 3C
C
C
H2
C
H2
C
H2
C
H2
N
O
N
N
CH3
N
CH3
A.
B.
C.
D.
E.
360.
H 3C
Proserin
Theobromine
*Pentoxifylline
Diprophylline
Euphylline
What medical drug has the following structural formula?
O
N
NH
H2C
NH2
H 2C
NH2
*
O
N
361.
CH3
Caffeine
Theophylline
Diprophylline
Pentoxifylline
*Euphylline
What medical drug has the following structural formula?
A.
B.
C.
D.
E.
N
O
OH
H3C
N
O
N
A.
B.
C.
D.
E.
362.
H3C
O
N
C
H2
C
H
CH2OH
N
CH3
Caffeine
Theophylline
*Diprophylline
Pentoxifylline
Euphylline
What medical drug has the following structural formula?
O
OH
N
N
N
N
C
H2
C
H
C
H2
N
COOH
CH3
*
CH2CH2OH
N
CH3
A. Diprophylline
B. Physostigmine salicylate
C. Pentoxifylline
D. *Xanthinol nicotinate
E. Euphylline
363.
Separate accordingly equipped production area for the production (manufacturing)
of medicines in the pharmacy - it is:
A. A block
B. *An assistant room
C. A production room
D. A production department
E. A material room
364.
Documentation that a particular method, process, equipment, activity or system of
actions lead to the expected and guaranteed result – it is:
A. A technological order
B. AND
C. *A validation
D. A contamination
E. A calibration
365.
Complex of preventive measures and types of control that is carried out right in the
drugstore – it is:
A. A factory control
B. A quality check
C. An exclusion of unfit drugs
D. A laboratory control
E. *A control within a drugstore
366.
For the preparation of intravenous infusions, injections, which are not subjected to
thermal sterilization, it is necessary to use sterile water:
A. Purified
B. *For injections
C. High purity
D. Drinking
E. Distilled
367.
All types of control within a drugstore should possess:
A. Pharmacist analyst, pharmacist
B. Head of drugstore, chemist
C. *Head of drugstore, his assistants, pharmacist analyst, chemist
D. Pharmacist, nurse
E. Head of drugstore, his assistants
368.
What kind of control is obligatory and is to check the appearance of a medicinal
product, including the quality of blockage, its color, smell, homogeneity of mixing, the lack
of mechanical insertions in liquid medical products?
A. Written
B. Chemical
C. Questionnaire
D. Control at selling
E. *Organoleptic
369.
Purified water (not for injections) is checked for the absence of admixtures:.
A. Chlorides, restoration matter and ammonia
B. Radioactivity only if there is an analyst in the staff
C. *Chlorides, sulfates, calcium salts
D. Heavy metals, arsenic, aluminum
E. Ammonia oxidizing agents, magnesium
370.
Water, from which injection solutions and medicines for infants are prepared, is
checked in the drugstore for:
A. *Chlorides, sulfates, calcium and ammonium salts, carbon dioxide of reducing substances
B. Nitrates, heavy metals
C. Reducing substances, ammonia
D. Calcium salts, arsenic
E. Heavy metals, sulfates
371.
The result of the reaction in the determination of chloride ions in the purified water
is:
A. Gray sendiment
B. *Opalescence
C. Yellowing of the solution
D. The appearance of pink color
E. The appearance of brown color
372.
An internal document of management agent, which defines the technological
methods, technical means, rules and regulations of medical product manufacturing, methods
of control, and establish quantitative and qualitative indicators of medical product, its
acceptable bounds, the requirements for packaging, marking, storage conditions, serviceable
life is called :
A. Technological order
B. *Technological direction
C. Validation
D. Contamination
E. Calibration
373.
Medicines are given handly application state, which provides them with the desired
medicinal effect and it is called:
A.
B.
C.
D.
E.
*Medicinal form
Medicinal species
Medical product
Medical form
Factory packaging
Contamination of concentrated solutions, intermediates and patent medicines is
374.
called:
A. Validation
B. Constopation
C. Rejects
D. *Contamination
E. Microbiological purity
375.
Form of within a drugstore storage without dosage, previously produced in the
drugstore mixture of two or more drugs that are combined in proportions, that often occur
in prescriptions of medicines is called:
A. Concentrates
B. Blends
C. *Semi finished products
D. Fixanales
E. Manufactured goods
376.
For the preparation of eye drops, which are subjected to further thermal sterilization,
it is necessary to use the following type of water:
A. Distilled
B. *Cleaned in containers
C. Drinking
D. For injections
E. From tap
377.
What type of control is not used in the pharmacy:
A. Written
B. Chemical
C. Physics
D. *Laboratory
E. Questionnaire
378.
What control lies in verifying the total weight or volume of a medicinal product,
quantity and mass of individual doses, which are included in this dosage form (but not less
than three doses)?
A. Written
B. Chemical
C. *hysics
D. Laboratory
E. Questionnaire
379.
Water for injections and eye drops are checked for the absence of admixtures:
A. Oxalates, phenols, iron, zinc, cyanides
B. *Chlorides, sulfates, calcium salts, reducing substances, ammonia and carbon dioxide
C. Reducing substances, ammonia, carbon dioxide and lead salts
D. Heavy metals, ammonia, fluoride
E. Heavy metals, arsenic, aluminum
380.
Head of pharmacy, his deputy, chemist, pharmacist analyst must possess within a
drugstore types of control:
A. Individual
B. Questionnaire
C. All species except chemical
D. Just admission
E. *All types
381.
In determining the calcium ions in purified water test solution is compared with:
A. Distilled water
B. *Standard solution
C. Purified water
D. Alcohol
E. Another calcium solution
382.
Sodium salt, wetted with chloride acid and put into a colorless flame, stains it in the
following color:
A. Red
B. Green
C. *Yellow
D. Violet
E. Brick red
383.
To identify potassium ions in extemporal medical forms chemist analyst may use the
following reagents:
A. Ammonium oxalate
B. *Sodium hexonitrocobalt (III) in presence of CH3COOH
C. Sodium hexohydroxostibatin
D. Silver nitrate in the nitrate acid medium
E. Potassium dichromate in the sulphate acid medium
384.
Medical product that contains hexamethylenetetramine and sodium salicylate was
received for analysis. What reagent when heated can detect simultaneously these two
preparations?
A. Sodium hydroxide
B. Concentrated chloride acid
C. *Sulphate acid concentrated
D. Sulphate acid diluted
E. Sodium nitrite
385.
Pharmacist analyst analyzes the quality control of medical form, which contains boric
acid. Identification of the latter is carried out with the help of boromethylic esther
formation, which burns with the flame that has edging of the following colour:
A. Yellow
B. *Green
C. Blue
D. Red
E. Brown
386.
To identify analgin in extemporal medical forms the following reagents may be used:
A. *Chloride acid diluted, chloramine solution
B. Sodium hydroxide, chloramine solution
C. Nitrate acid, silver nitrate
D. Hydrogen peroxide solution, ammonia solution
E. Chloride acid diluted, sodium nitrite
387.
To identify streptocid in medical form one adds chloride acid, sodium nitrite solution,
β-naphthol solution. During this process azo dye appears and it is colored:
A. Yellow
B. Blue
C. Green
D. *Cherry red
E. Black
388.
For rapid qualitative analysis of novocaine in medical forms the following reaction is
used:
A. Murexide test
B. *Lignine test
C. Legal
D. Pellagry
E. Diazotization
389.
Sodium benzoate and sodium salicylate are defined in rapid analysis simultaneously
with the help of the following solution:
A. *Iron (III) chloride
B. Sodium nitrite
C. Cobalt (II) nitrate
D. Sulphate acid
E. Silver nitrate
390.
To identify bromide ions in medical form analyst used solution of silver nitrate. He
will observe the formation of the following sediment:
A. White, which is light soluble in ammonia
B. White, which is insoluble in ammonia
C. Light yellow, which is easily soluble in ammonia solution
D. *Light yellow, which is soluble in concentrated ammonia solution
E. Yellow, which is soluble in ammonia
391.
To identify chloride ions in extemporal medical forms chemist analyst may use the
following reagents:
A. Ammonium oxalate
B. Sodium cobaltnitrite in the presence of CH3COOH
C. *Silver nitrate in the nitrate acid medium
D. Potassium hexahydroxystibatin after previously added potassium carbonate and boiling
and then cooling
E. Potassium dichromate in sulphate acid medium
392.
The following medical form was sent to analysis: ascorbic acid 0.1 and glucose 0.5. On
what chemical properties of both drugs is based the qualitative rapid analysis of this medical
preparation?
A. Acid
B. Main
C. Oxidative
D. *Restoration
E. Amphoteric
393.
Acetylsalicylic acid in the extemporal drugs is determined by the following reagent:
A. *Marky
B. Legal
C. Dragendorf
D. Raymond
E. Erdman
394.
To identify calcium ions in extemporal medical forms chemist analyst may use the
following reagents:
A. *Ammonium oxalate in the presence of CH3COOH
B. Sodium cobaltinitrite in the presence of CH3COOH
C. Silver nitrate in the nitrate acid medium
D. Potassium hexahydroxystibatin after previously added potassium carbonate and boiling
and then cooling
E. Potassium dichromate in sulphate acid medium
395.
To identify ammonium ions extemporal medical form is heated with a solution of
sodium hydroxide. In this case, there is the smell of:
A.
B.
C.
D.
E.
Phenol
Amine
*Ammonia
Sulphur oxide
Nitric oxide (IV)
396.
Novocaine and resorcin in medical preparations can be identified simultaneously by
using the following reagents:
A. Diluted chloride acid, solution of chloramine
B. Sodium hydroxide, chloramine solution
C. Nitrate acid, silver nitrate
D. Hydrogen of peroxide solution, ammonia solution
E. *Diluted chloride acid, sodium nitrite and sodium hydroxide solutions
397.
Medical form which contains hexamethylenetetramine and sodium salicylate was sent
to analysis. At heating it with sulphate acid there appears:
A. White sediment
B. *Raspberry-red color
C. Yellow color
D. Yellow sediment
E. Green color
398.
For qualitative rapid analysis of aminophylline in drugs the following reaction is
used:
A. *Murexide sample
B. Lignine sample
C. Legal
D. Pellagry
E. Diazotization
399.
Medical form which contains hexamethylenetetramine and streptocid was sent to
analysis. What reagent at the process of heating can simultaneously detect the two drugs?
A. Sodium hydroxide
B. Concentrated chloride acid
C. Sulfate acid concentrated
D. *Sulphate acid diluted
E. Sodium nitrite
400.
Chloride acid in extemporal medical forms is identified by the following solution:
A. Phenolphthalein
B. Starch
C. *Methyl red
D. Thymolphthalein
E. Bromphenol blue
401.
Sodium benzoate and sodium salicylate are simultaneously defined in rapid analysis
with the following solution:
A. *Iron (III) chloride
B. Sodium nitrite
C. Cobalt (II) nitrate
D. Sulphate acid
E. Silver nitrate
402.
One of the reactions to identify potassium ions is the reaction with sodium
cobaltnitrit. Analytical effect in this case is:
A. Gassing
B. The formation of white sediment which is soluble in ammonia
C. The formation of white sediment, which is insoluble in acetate acid
D. *The formation of yellow or orange-yellow sediment, which is insoluble in acetate acid
E. Opalescence
403.
Select a reagent which is used to identify any of the anions (chloride, bromide, iodide)
in their common presence in drugs:
A. Iron (II) sulfate
B. Sodium nitrite
C. Cobalt (II) nitrate
D. Sulphate acid
E. *Silver nitrate
404.
The following medical form was sent to analysis: ascorbic acid 0.1 and glucose 0.5.
Silver nitrate is added to the powder solution to reveal ascorbic acid. In this case, the
following analytical effect is observed:
A. White sediment
B. Pink color
C. *Gray sediment
D. Gassing
E. Blue color
405.
Acetylsalicylic acid in extemporal drugs is determined by the solution of:
A. *Iron (III) chloride
B. Sodium nitrite
C. Cobalt (II) nitrate
D. Sulphate acid
E. Silver nitrate
406.
Medical form of the following composition was sent to analysis: sodium chloride 0.2;
sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml.
Quantitative determination of sodium chloride is carried out by:
A. Argentometry of Folgard
B. Alkalimetry
C. Argentometry of Mor
D. Acidimetry
E. *Argentometry of Fajans
407.
Medical form of the following composition was sent to analysis: sodium chloride 0.2;
sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. The
amount of sodium hydrocarbonate and sodium tetraborate is quantitated by:
A. Argentometry of Folgard
B. Alkalimetry
C. Argentometry of Mor
D. *Acidimetry
E. Argentometry of Fajans
408.
Medical form of the following composition was sent to analysis: sodium chloride 0.2;
sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. The
content of sodium tetraborate after convertion into boric acid is quantitatively determined
by the method of:
A. Argentometry of Folgard
B. *Alkalimetry
C. Argentometry of Mor
D. Acidimetry
E. Argentometry of Fajans
409.
Medical form of the following composition was sent to analysis: sodium chloride 0.2;
sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml.
Quantitative determination of sodium chloride by titration of 1 ml of the medical
preparation by standard 0.1 M of the following solution:
A. Chloride acid
B.
C.
D.
E.
Sodium hydroxide
*Silver nitrate
Sodium edetate
Sodium thiosulfate
410.
Medical form of the following composition was sent to analysis: sodium chloride 0.2;
sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. Amount
of sodium bicarbonate and sodium tetraborate quantitated by titrating 1 ml of the medical
preparation by standard 0.1 M of the following solution:
A. *Chloride acid
B. Sodium hydroxide
C. Silver nitrate
D. Sodium edetate
E. Sodium thiosulfate
411.
Medical form of the following composition was sent to analysis: sodium chloride 0.2;
sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. The
content of sodium tetraborate after converted into boric acid was quantitatively determined
by titrating 1 ml of the medical preparation by standard 0.1 M of the following solution:
A. Chloride acid
B. *Sodium hydroxide
C. Silver nitrate
D. Sodium edetate
E. Sodium thiosulfate
412.
Medical form of the following composition was sent to analysis: sodium chloride 0.2;
sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml.
Quantitative determination of sodium chloride is conducted by argentometry using as an
indicator the solution of:
A. Phenolphthalein
B. Methyl orange
C. Potassium chromate
D. Iron ammonium sulfate
E. *Bromophenol blue
413.
Medical form of the following composition was sent to analysis: sodium chloride 0.2;
sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. The
amount of sodium hedrocarbonate and sodium tetraborate quantitavely is determined by
acidimetry using as an indicator the solution of:
A. Phenolphthalein
B. *Methyl orange
C. Potassium chromate
D. Iron ammonium sulfate
E. Bromophenol blue
414.
Medical form of the following composition was sent to analysis: sodium chloride 0.2;
sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. The
content of sodium tetraborate is determined by alkalimetry after convertion into boric acid
using as an indicator the solution of:
A. *Phenolphthalein
B. Methyl orange
C. Potassium chromate
D. Iron ammonium sulfate
E. Bromophenol blue
415.
Medical form of the following composition was sent to analysis: sodium chloride 0.2;
sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. The
content of sodium tetraborate is determined by alkalimetry after convertion into boric acid
by adding neutralizing to phenolphthalein:
A. Formaldehyde
B. *Glycerin
C. Chloroform
D. Ethanol
E. Ether
416.
Medical form of the following composition was sent to analysis: solution of zinc
sulphate 0,25% - 10,0 ml; boric acid 0,2. The quantitative determination of zinc sulfate is
carried out by:
A. Argentometry
B. Alkalimetry
C. Iodometry
D. Acidimetry
E. *Complexometry
417.
Medical form of the following composition was sent to analysis: solution of zinc
sulphate 0,25% - 10,0 ml; boric acid 0,2. The quantitative determination of boric acid is
carried out by:
A. Argentometry
B. *Alkalimetry
C. Iodometry
D. Acidimetry
E. Complexometry
418.
Medical form of the following composition was sent to analysis: solution of zinc
sulphate 0,25% - 10,0 ml; boric acid 0,2. The quantitative determination of zinc sulphate is
carried out by titrating 1 ml of the medical preparation by standard 0.01 M of the following
solution:
A. Chloride acid
B. Sodium hydroxide
C. Silver nitrate
D. *Sodium edetate
E. Sodium thiosulfate
419.
Medical form of the following composition was sent to analysis: solution of zinc
sulphate 0,25% - 10,0 ml; boric acid 0,2. The quantitative determination of boric acid is
carried out by titrating 0,5 ml of the medical preparation by standard 0.01 M of the
following solution:
A. Chloride acid
B. *Sodium hydroxide
C. Silver nitrate
D. Sodium edetate
E. Sodium thiosulfate
420.
Medical form of the following composition was sent to analysis: solution of zinc
sulphate 0,25% - 10,0 ml; boric acid 0,2. The quantitative determination of zinc sulfate is
carried out by complexometry in the following medium:
A. Chloride acid
B. Sodium hydroxide
C. Buffer solution of pH 3,5
D. Phosphate buffer solution
E. *Ammonia buffer solution
421.
Medical form of the following composition was sent to analysis: solution of zinc
sulphate 0,25% - 10,0 ml; boric acid 0,2. In the quantitative determination of zinc sulfate to
indicate the equivalence point the following mixture is used:
A. *Acid dark blue
B.
C.
D.
E.
Tropeolin 00 and methylene blue
Methyl orange and methylene blue
Methyl red and methylene blue
Bromophenol blue and bromthymol blue
422.
Medical form of the following composition was sent to analysis: solution of zinc
sulphate 0,25% - 10,0 ml; boric acid 0,2. For the quantitative determination of boric acid at
first deposition of zinc sulfate is carried out by the solution of:
A. Silver nitrate
B. *Potassium ferrocyanide (II)
C. Potassium ferrocyanide (III)
D. Barium chloride
E. Ammonium oxalate
423.
Medical form of the following composition was sent to analysis: solution of zinc
sulphate 0,25% - 10,0 ml; boric acid 0,2. The content of boric acid is determined by
alkalimetry by adding neutralizing to phenolphthalein:
A. Formaldehyde
B. *Glycerine
C. Chloroform
D. Ethanol
E. Ether
424.
Medical form of the following composition was sent to analysis: solution of zinc
sulphate 0,25% - 10,0 ml; boric acid 0,2. What is the molar mass of zinc sulfate equivalent in
the quantitative determination of it by the method of complexometry?
A. 1/4 М. m.
B. 2 М. m.
C. *М. m.
D. 1/2 М. m.
E. 1/5 М. m.
425.
Medical form of the following composition was sent to analysis: solution of zinc
sulphate 0,25% - 10,0 ml; boric acid 0,2. What is the molar mass of boric acid equivalent in
the quantitative determination of it by the method of alkalimetry?
A. 1/4 М. m.
B. 2 М. m.
C. *М. m.
D. 1/2 М. m.
E. 1/5 М. m.
426.
Pharmacist analyst analyzes the following medical product composition: ascorbic
acid 0.1, glucose 0.5. At the same time ascorbic acid is quantified by the method of:
A. A Argentometry of Mor
B. Alkalimetry, reverse titration
C. *Iodometry, direct titration
D. Acidimetry, direct titration
E. Complexometry
427.
Pharmacist analyst analyzes following medical product composition: ascorbic acid
0.1, glucose 0.5. At the same time glucose is quantified by the method of:
A. Argentometry of Mor
B. Alkalimetry, reverse titration
C. *Iodometry, direct titration
D. Acidimetry, direct titration
E. Complexometry
428.
Pharmacist analyst analyzes following medical product composition: ascorbic acid
0.1, glucose 0.5. At the same time glucose is quantified by the iodometry method using as an
indicator the solution of:
A. Methyl orange
B. *Starch
C. Phenolphthalein
D. Bromophenol blue
E. Tropeolin 00
429.
Pharmacist analyst analyzes following medical product composition: ascorbic acid
0.1, glucose 0.5. At the same time both components are quantified in a single sample of
powder by the method of:
A. Argentometry
B. Alkalimetry
C. *Iodometry
D. Acidimetry
E. Complexometry
430.
Pharmacist analyst analyzes following medical product composition: ascorbic acid
0.1, glucose 0.5. Quantitative determination of both components in a single batch of powder
based on the following their chemical properties:
A. Main
B. Acid
C. Oxidative
D. *Restoration
E. Amphoteric
431.
Pharmacist analyst analyzes following medical product composition: ascorbic acid
0.1, glucose 0.5.What is the molar mass of ascorbic acid equivalent in the quantitative
determination of it by the method of iodometry, direct titration?
A. 1/4 М. m.
B. 2 М. m
C. М. m.
D. *1/2 М. m.
E. 1/5 М. m.
432.
Pharmacist analyst analyzes following medical product composition: ascorbic acid
0.1, glucose 0.5.What is the molar mass of glucose equivalent in the quantitative
determination of it by the method of iodometry, direct titration?
A. 1/4 М. m.
B. 2 М. m.
C. М. m.
D. *1/2 М. m.
E. 1/5 М. m.
433.
Pharmacist analyst analyzes following medical product composition: ascorbic acid
0.1, glucose 0.5. In the quantitative determination of ascorbic acid by the iodometry method
titration is carried out until the non-vanishing staining of the following colour appears:
A. *Yellow
B. Blue
C. Red
D. Violet
E. Green
434.
What kind of admixture in the purified water “in bulk” is determined by the reaction
chemistry of which is depicted in picture?
[O]
N
H
2
N
H
H2SO4êî í ö.
N
H
[O]
N
N
H
H2SO4êî í ö.
-
+
HSO4
A.
B.
C.
D.
E.
Heavy metals
*Nitrates
Substances that are oxidized
Aluminum
Electric conductivity
435.
What reagent reveals nitrate admixtures in the purified water in containers on the
reaction chemistry of which is depicted in picture?
[O]
N
H
2
N
H
H2SO4êî í ö.
N
H
[O]
N
N
H
H2SO4êî í ö.
-
+
HSO4
A.
B.
C.
D.
E.
Aniline
Ethylenediamine
Phenylamine
Dibenzylamine
*Diphenylamine
436.
What is the analytical effect of the reaction of nitrate admixture identification in
water for injections “in bulk” the chemistry of which is represented in picture?
[O]
N
H
2
N
H
H2SO4êî í ö.
N
H
[O]
N
N
H
H2SO4êî í ö.
-
+
HSO4
A.
B.
C.
D.
E.
Green coloration
Red sediment
*Blue coloration
Red coloration
White sediment
437.
What kind of admixture in the purified water “in bulk” is determined by the reaction
chemistry of which of is depicted in picture?
SH
S
H3C
H3C
C
NH
NH2
H3C
C
NH
A. *Heavy metals
B. Nitrates
C. Substances that are oxidized
S
S
SH
Me2+ + 2 H3C
;
C
Me
C
N
H
C
N
H
CH3 +
2H+.
D. Aluminum
E. Electric conductivity
438.
What reagent reveals the heavy metals admixture in the purified water in containers
on the reaction the chemistry of which is depicted in picture?
SH
S
H3C
H3C
C
NH
NH2
H3C
C
S
S
SH
Me2+ + 2 H3C
;
C
Me
C
C
N
H
NH
CH3 +
2H+.
N
H
A.
B.
C.
D.
E.
8-oxine
Thiourea
Thioglycolic acid
Diphenylamine
*Tioacetamide
439.
What is the analytical effect of the heavy metals admixture detection reaction in
water for injections “in bulk” the chemistry of which is described in picture?
SH
S
H3C
H3C
C
NH
NH2
H3C
C
NH
S
S
SH
Me2+ + 2 H3C
;
C
Me
C
N
H
C
CH3 +
2H+.
N
H
A.
B.
C.
D.
E.
Green coloration
Red sediment
*Brown coloration
Blue coloration
White sediment
440.
What reagent reveals the ammonium salts admixture in the purified water in
containers on the reaction the chemistry of which is depicted in picture?
NH4+ + 2[HgI4]2- + 2OH-
[NH2Hg2I2] I + 5I- + 2H2O
A.
B.
C.
D.
E.
Dragendorf
Tollens
Diphenylamine
Tioacetamide
*Nesler
441.
What is the analytical effect of the ammonium salts admixture detection reaction in
the purified water in containers the chemistry of which is represented in picture?
NH4+ + 2[HgI4]2- + 2OHA.
B.
C.
D.
E.
[NH2Hg2I2] I + 5I- + 2H2O
Green coloration
Red sediment
*Yellow coloration
Brown coloration
White sediment
442.
What is the analytical effect of the chlorides admixture detection reaction in the
purified water in containers the chemistry of which is described in picture?
Cl- + Ag+
HNO3
AgCl
A.
B.
C.
D.
E.
White coloration
Red sediment
*Opalescence
Yellow sediment
White sediment
443.
What is the analytical effect of the sulphate admixture detection reaction in the
purified water in containers the chemistry of which is depicted in picture?
HCl
SO42- + Ba2+
BaSO4
A.
B.
C.
D.
E.
White coloration
Red sediment
*Opalescence
Yellow sediment
White sediment
444.
What is the analytical effect of the reaction with the help of which pharmacist analyst
conducts qualitative rapid analysis of the thiamine hydrochloride solution, and the
chemistry of which is represented in picture?
CH3
CH3
H2C
N
+
-
N
O
C
HS
S
H3C
N
+
N
Cl *HCl + NaOH
N
H2C
CH2CH2OH
N
H3C
NH2
H
CH2CH2OH
NH2
CH3
N
+
N
K3[Fe(CN)6]
N
H3C
N
S
CH2CH2OH .
A.
B.
C.
D.
E.
Red coloration
*Blue fluorescence
Blue coloration
White sediment
Yellow fluorescence
445.
What is the reaction by which pharmacist analyst conducts qualitative rapid analysis
of the thiamine hydrochloride solution, and the chemistry of which is described in picture?
CH3
CH3
H2C
N
+
-
N
CH2CH2OH
H3C
NH2
CH3
N
+
O
C
HS
S
H3C
N
+
N
Cl *HCl + NaOH
N
H2C
N
K3[Fe(CN)6]
H3C
N
A. Tallium test
B. *Thiochrome test
C. Hydroxamic reaction
N
S
CH2CH2OH .
N
H
NH2
CH2CH2OH
D. The reaction of Vitaly-Moren
E. Maltase test
446.
The test mixture sample, which contains 0,005-0,01 g of purine alkaloid was placed
into the porcelain cup, added 3 drops of HCl diluted, 5 drops of perhydrol and evaporated
to dryness on water bath . A drop of NH4OH was added to the residue. What is the
combination that is formed as a result of this reaction and is depicted in picture?
O
O
H3C
CH3
N
O
N
N
O
H4NO
CH3
N
O
N
CH3
A.
B.
C.
D.
E.
Tallium
Diphenylcarbinol
1,3-Dimethylalloxan
Methylalloxan
*Murexide
447.
1 ml of NaOH solution and 1 ml of 0.5% solution of alpha-naphthol in 40% ethanol
was added to 5 ml of 0.5% streptomycin sulfate solution. The mixture was cooled up to 15 º
C and there was added 3 drops of 5% sodium hypobromide solution. What is the color of the
compound, which was formed as a result of this reaction and is depicted in picture?
O
OH
NH
A.
B.
C.
D.
E.
Green
Red
*Violet
Blue
White
448.
What is the analytical effect of the reaction with the help of which pharmacist analyst
conducts qualitative rapid analysis of the streptomycin sulfate solution, and the chemistry of
which is represented in picture?
O
O
CHO
0
NaOH, t C
CH3
OH
OH
OH
A.
B.
C.
D.
E.
3+
Fe /3
O
O
OH
FeCl3
CH3
HCl
O
+ HCl .
CH3
O
Red coloration
*Violet coloration
Blue fluorescence
White sediment
Yellow fluorescence
449.
What is the reaction by which pharmacist analyst conducts qualitative rapid analysis
of the streptomycin sulfate solution, and the chemistry of which is described in picture?
A.
B.
C.
D.
E.
Tallium test
*Maltase test
Thiochrome test
The reaction of Sakaguchy
The reaction of Vitaly-Moren
450.
Pharmacist analyst conducts qualitative rapid analysis of the powder. For this
purpose he dissolves the investigated material in 0.1 M of sodium hydroxide solution and
adds 2 drops of cobalt nitrate solution. Complex salt of cobalt with the following structure is
formed:
O
C6H5
O
C6H5
C6H5
Co
C6H5
N
O
N
H
N
O
N
H
O
O
What is the analytical effect of this reaction?
A. Red coloration
B. Blue fluorescence
C. Blue coloration
D. White and pink sediment
E. *Violet sediment
451.
What is the analytical effect of the reaction with the help of which pharmacist analyst
conducts qualitative rapid analysis of the formaldehyde solution, and the chemistry of which
is represented in picture?
HO
H
+
H
C
H
+
H
OH
O
HOOC
H2SO4
COOH
H
HO
C
[O]
OH
H
HOOC
HO
HOOC
COOH
C
H
O
.
COOH
A.
B.
C.
D.
E.
Blue coloration
*Red coloration
Blue fluorescence
White sediment
Yellow fluorescence
452.
What reagent is used for qualitative rapid analysis of formaldehyde solution on the
reaction chemistry of which is depicted in picture?
CH2O + K2[HgI4] + 3KOH
A.
B.
C.
D.
E.
Dragendorf
Tollens
Lugol
Felling
*Nessler
Hg + HCOOK + 4KI + 2H2O
453.
Pharmacist analyst conducts qualitative rapid analysis of the drug. He adds a drop of
concentrated HNO3 to 0,001 grams of the investigated powder and heats it. Colored
compound of the following structure is formed:
H3CO
N
H3CO
O 2N
CH2
NO2
H3CO
OCH3
Which drug was received for analysis?
A. Aminazine
B. Phenylephrine hydrochloride
C. Morphine hydrochloride
D. Riboflavin
E. *Papaverine hydrochloride
454.
Pharmacist analyst conducts qualitative rapid analysis of the drug. He adds a drop of
concentrated HNO3 to 0,001 grams of the investigated powder and heats it. What is the
color of the compound of the following structure which was formed as the result of the
described reaction?
H3CO
N
H3CO
O 2N
CH2
NO2
H3CO
OCH3
A.
B.
C.
D.
E.
Red
Violet
Blue
Red
*Orange
455.
What is the analytical effect of the reaction with the help of which pharmacist analyst
conducts qualitative rapid analysis of the adrenaline hydrochloride solution, and the
chemistry of which is represented in picture?
HO
O
ClFe
OH
HO
C
H
CH2 + FeCl3
NHCH3
A.
B.
C.
D.
E.
Red coloration
*Emerald green coloration
Blue fluorescence
White and pink sediment
Yellow orange sediment
O
OH
C
H
CH2 + 2HCl
NHCH3
456.
What is the analytical effect of the reaction with the help of which pharmacist analyst
conducts qualitative rapid analysis of the adrenaline hydrochloride solution, and the
chemistry of which is represented in picture?
O
HO
O
OH
I2
HO
C
H
CH2
pH 3,56
CH
OH
NHCH3
N
CH2
H3C
A.
B.
C.
D.
E.
Emerald green coloration
*Dark red coloration
Blue fluorescence
White and pink sediment
Yellow orange sediment
457.
Pharmacist analyst conducts qualitative rapid analysis of the drug. For this purpose
he heats 0,1 g of the investigated powder in the test tube of 2 ml filled with diluted chloride
acid. The chemistry of this reaction is depicted in picture:
H3C
H3C
N
NaO3S
CH3
O
N
HCl
CH2
N
CH3
H
CH3
N
N
O
C6H5
CH3
N
C6H5
SO2+CH2O+NaCl
What medicine was received for analysis?
A. Benzylpenicillin sodium salt
B. Sodium caffeine-benzoate
C. *Metamizol sodium salt
D. Diclofenac sodium
E. Vicasol
458.
Pharmacist analyst conducts qualitative rapid analysis of the drug. For this purpose
he adds 1-2 drops of concentrated H2SO4 to 0,001 grams of the investigated powder.
Colored compound of the following structure is formed:
CH
H
H
O+ CH2 CH2
N+
CH3
2-
SO4
CH3
2
What drug was received for analysis?
A. Aminazine
B. Mesaton
C. Analgin
D. Levomycetin
E. *Dimedrol
459.
Pharmacist analyst conducts qualitative rapid analysis of the drug. For this purpose
he adds 1-2 drops of concentrated H2SO4 to 0,001 grams of the investigated powder. What
is the color of the compound of the following structure which was formed as the result of the
described reaction?
CH
H
H
O+ CH2 CH2
N+
CH3
2-
SO4
CH3
2
A.
B.
C.
D.
E.
Red
Violet
Blue
Pink
*Orange