Мodule 5 Analysis of the quality of drugs from the group of biologically active substances of natural origin and extemporal preparations 1. Determine the molecular mass of the ascorbic acid equivalent at its assay by alkalimetry, direct titration: A. *М.m. B. М.m./2 C. М.m./4 D. М.m./8 E. 2 М.m. 2. Choose the reagent for ascorbic acid identification: A. *Silver nitrate solution, nitrate acid B. Dragendorff’s reagent C. Barium chloride solution D. 2,4-dinitrochlorbenzene E. Hydroxylamine hydrochloride 3. Calcium ion in the calcium pangamate can be detected with following reagent: A. Silver nitrate B. *Ammonium oxalate C. Hydrochloric acid D. Hydrogen peroxide E. Potassium dichromate 4. Assay of calcium pantothenate is conducted by the following method: A. Argentometry B. Iodometry C. Permanganatometry D. *Complexonometry E. Alkalimetry 5. What compound does belong to vitamins of the alicyclic row? A. Thiamine bromide B. *Retinol acetate C. Vikasol D. Ascorbic acid E. Nicotinic acid 6. What reagents can be used for ergocalciferol identification? A. 2,4-dinitrochlorobenzene, potassium hydroxide alcohol solution B. Sodium nitrite, β-naphthalene alkaline solution C. Chloral hydrate, chloroform D. *Acetylchloride, antimony (ІІІ) chloride, chloroform E. Cerium sulfate, diphenylamine 7. Calcium pantothenate is a vitamin preparation, in the medical practice it is used under the name – vitamin: A. *В5 B. В15 C. ВС D. В6 E. В3 8. Retinol acetate by the chemical method can be obtained from: A. Ergosterine B. Fructose C. L-streptose D. *Citral E. Maltose 9. Ergocalciferol is used in the medical practice for the treatment of: A. Blood diseases B. Goiter C. Cataract D. Atherosclerosis E. *Rachitis 10. Assay of ascorbic acid according to the SPhU requirements is conducted by the following method: A. Complexonometry B. Acidimetry in non-aqueous environment C. Alkalimetry in aqueous environment D. Iodatomerty E. * Iodomerty 11. Ascorbic acid in industry is obtained from: A. Furfural B. Fructose C. L-streptose D. *D-glucose E. Maltose 12. Gluconic acid residue in the calcium pangamate molecule is detected by the following solution: A. Silver nitrate B. 2,6-dichlorophenolindophenol C. Ammonium oxalate D. *Iron (ІІІ) chloride E. Sodium hydroxide 13. Calcium pangamate belongs to the vitamins of: A. Alicyclic row B. Aromatic row C. *Aliphatic row D. Heterocyclic row E. Polyene row 14. Residue of -alanine in the calcium pantothenate molecule is determined by usage of the following solution: A. CuSO4 in H2SO4 B. Sodium nitroprusside C. *CuSO4 in NaOH D. Formaldehyde E. CuSO4 in HCl 15. What reagent can be used to identify retinol acetate in the presence of chloroform? A. Hydrochloric acid B. *Antimony (ІІІ) chloride C. Sodium nitrite D. Vanillin E. Sodium nitroprusside 16. Ergocalciferol also can be named as vitamin: A. В5 B. В2 C. Е D. *D2 E. А 17. For calcium-ion detection in the calcium pangamate molecule the following reagent is used: A. Silver nitrate B. *Glyoxal hydroxyanil C. Hydrochloric acid D. Hydrogen peroxide E. Potassium dichromate 18. Calcium chloride in the calcium pangamate substance is quantitatively determined by the following method: A. Alkalimetry B. Argentometry by Mor’s method C. *Argentometry by Folgard method D. Acidimetry E. Complexonometry 19. Molecular mass of the ascorbic acid equivalent at the quantitative determination by iodometric method equals: A. М.m. B. *М.m./2 C. М.m./4 D. М.m./8 E. 2 М.m. 20. Chemical name γ-lactone-2,3-dihydro-L-gulonic acid the following compound has: A. Vikasol B. Rutin C. Ergocalciferol D. Riboflavin E. *Ascorbic acid 21. Choose the reagent for ascorbic acid identification: A. Dragendorff’s reagent B. Barium chloride solution C. *2,6-dichlorophenolindophenol D. 2,4-dinitrochlorobenzene E. Hydroxylamine hydrochloride solution 22. Pharmacist-analyst did calcium pangamate identification by hydroxamic reaction. What functional group does this reaction identify in the structure of calcium pangamate? A. Ion Са2+ B. *Ester group C. Hydroxide group D. Methyl radical E. Tertiary amine 23. Calcium ion in the calcium pangamate can be detected by following method: A. Argentometry B. Permanganatometry C. Alkalimetry D. *Complexonometry E. Acidimetry 24. Calcium pantothenate is used in the medical practice for the treatment of: A. *Metabolic disorders B. Eyes diseases C. Heart diseases D. Gastro-intestinal tract disorders E. Gynecological diseases 25. Retinol acetate is a vitamin preparation, in the medical practice it is used under the name – vitamin: A. В5 B. D2 C. Е D. К E. *А 26. What compound does belong to vitamins of the alicyclic row? A. Thiamine bromide B. Calcium pangamate C. Vikasol D. *Ergocalciferol E. Nicotinic acid 27. Ascorbic acid belongs to the vitamins group of: A. Pyrimidine derivatives B. Pterine derivatives C. *Aliphatic row D. Tropane derivatives E. Acridine derivatives 28. Vikasol is a synthetic analog of vitamin: A. А B. В C. С D. Е E. *К 29. Tocopherol acetate has the following chemical name: A. Pregnane–4-ol-21-dione-3,20-21 acetate B. Pregnene–4-diol-17-2,21-trione-3,11,20-21 acetate C. Pregnene–4-triol-11,17, 21-dione-3,20-21 acetate D. Trans-9,13-dimethyl-7-(1,1,5-trimethyl-cyclogen-5-yl-6)nontetraene-7,9,11,13-one–15 acetate E. *(+)-2,5,7,8,-tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-acetoxychromane 30. Routine is present in the following tablets content: A. Papazol B. No-spa C. *Ascoroutine D. Reoperin E. Citramone 31. Nicotinic acid belongs to the vitamins group of: A. Piperidine B. Pyrimidine C. *Pyridine D. Pyrazolone E. Pyrazol 32. What smell do you fell during the nicotineamide heating with crystalline sodium carbonate? A. Aniline B. *Ammonium C. Acetoacetic ether D. Fresh apples E. Bitter almond 33. At the pyridoxine hydrochloride assay by acidimetry in non-aqueous environment Hg(CH3CОO)2 is added for: A. *Halogen bonding in low-dissociated compound B. Enhance hydrolysis of the final product C. Inhibition of the final product hydrolysis D. Displacement of the reaction equilibrium to the right E. Displacement of reaction equilibrium to the left 34. Chloride-ion in the pyridoxine hydrochloride molecule can be detected with the usage of the following reagents: A. AgNO3, H2SO4 B. *K2Cr2O7, H2SO4 , diphenylcarbazide C. K2Cr2O7, diphenylcarbazone D. AgNO3, NaOH E. Diphenylcarbazide 35. Tocoferol acetate identification can be conducted with the following reagents: A. Conc. HCl at the heating B. KOH solution at the cooling, H2SO3 C. *K3[Fe(CN)6] solution in alkaline environment D. Vanillin in glycerin solution E. Hydroxylamine hydrochloride 36. What compound is an aglycone in the routine molecule? A. Streptidine B. *Quercetin C. Strophantidine D. Digitoxygenine E. Digoxigenin 37. Which of the following compounds has chemical name 2,3-dihydro-2-mathyl-1,4naphthoquinone-2 sulfonate? A. Ergocalciferol B. Riboflavin C. *Vikasol D. Cocarboxylase E. Rutin 38. Tocopherol acetate in the medical practice is used for the treatment of: A. *Functional disorders of the sexual organs B. Scurvy C. As antioxidant mean D. Liver cirrhosis E. As antiseptic mean 39. Assay of routine is conducted according to the AND requirements by the following method: A. Refractometry B. Polarimetry C. Potentiometry D. Paleography E. *Spectrophotometry 40. Choose the chemical name of nicotinic acid: A. Pyrimidine-3-carboxylic acid B. Piperidine-3-carboxylic acid C. Pyrimidine-2-carboxylic acid D. *Pyridine-3-carboxylic acid E. Pyridine-4-carboxylic acid 41. What smell do you feel during the nicotineamide boiling with sodium hydroxide? A. Aniline B. *Ammonium C. Phenol D. Pyridine E. Bitter almond 42. Determine the molecular mass of the pyridoxine hydrochloride equivalent at its assay by acidimetry in non-aqueous environment: A. 2 М.m. B. ½ М.m. C. 1/4 М.m. D. *М.m. E. 1/8 М.m. 43. Pyridoxine hydrochloride belongs to the vitamins, derivatives of: A. Piperidine B. Pyrimidine C. *Pyridine D. Pyrazolone E. Pyrazone 44. The nicotinic acid content of the injection solutions in accordance with the AND requirements was determined by the following method: A. Alkalimetry B. Acidimetry in non-aqueous environment C. *Cooper-iodometry D. Gravimetry E. Refractometry 45. What gas will evaporates after the nicotinamide heating with an alkali solution? A. CO2 B. N2 C. *NH3 D. O2 E. CO 46. Medical drug vikasol has the following chemical name: A. Sodium salt of 6-phenylacetylamino-penicillanic acid B. Sodium salt of p-aminosalicylic acid C. *Sodium 2,3-dihydro-2-methyl-1,4-naphthoquinone-2-sulfonate D. Sodium 5-ethyl-5-(2-amyl)-barbiturate E. Sodium p-(2,3-dimethylphenyl)-anthranyl 47. Assay of tocopherol acetate after hydrolysis according to AND requirements is conducted by the following method: A. Complexonometry B. Acidimetry in aqueous environment C. Alkalimetry in non-aqueous environment D. *Cerymetry E. Gravimetry 48. Pyridine cycle in the nicotinic acid is detected with: A. Potassium permanganate solution B. 2,6-dichlorophenolindophenol C. *2,4- dinitrochlorobenzene D. Iodostarch paper E. Felling reagent 49. Assay of nicotinamide according to the SPhU requirements is conducted by the following method: A. *Acidimetry in non-aqueous environment B. Iodometry C. Permanganatometry D. Acidimetry in aqueous environment E. Alkalimetry in non-aqueous environment 50. Which of the following substances has chemical name (5-hydroxy-6-methylpyridine-3,4diyl)-dimethanol hydrochloride? A. Novocain hydrochloride B. Cocaine hydrochloride C. Morphine hydrochloride D. *Pyridoxine hydrochloride E. Pilocarpine hydrochloride 51. Nicotinamide belongs to vitamins derivatives of: A. Piperidine B. Pyrimidine C. *Pyridine D. Pyrazolone E. Pyrazone 52. Vitamins of К group belong to the: A. Aromatic row B. Aliphatic row C. *Alicyclic row D. Heterocyclic row E. Polyene row 53. What reagents can be used for tocopherol acetate identification? A. Conc. HCl at the heating B. Alcoholic solution of KOH at the heating, conc. H2SO4 C. *Solution of K3[Fe(CN)6] at the presence of chloroform D. Vanillin in the glycerin solution E. Hydroxylamine hydrochloride 54. The sugar part in the routine molecule is: A. Streptobioseamine B. Digitoxose C. *Ramnose D. Ramnose, glucose E. Glucose 55. Which of the following methods is not used for the thiamine hydrochloride assay? A. Gravimetry B. Alkalimetry C. Acidimetry in non-aqueous environment D. *Bromatometry E. Fluorimetry 56. What reagents are used for the bromine-ion detection in thiamine hydrobromide molecule? A. K3[Fe(CN)6], NaOH, butyl alcohol B. AgNO3, NH3 C. NaNO3, HCl, -naphthalene alkaline solution D. *Chloramine, HCl, chloroform E. Sodium nitroprusside, KOH 57. Choose the specific admixture in the riboflavin molecule: A. Leukoribine B. Cocarboxylase C. Leukogen D. Leukobase E. *Lyumiflavin 58. What reagents can be used to identify riboflavin? A. Sodium sulfate, silver nitrate B. Diluted sulfate acid, ninhydrine C. *Concentrated sulfate acid, silver nitrate D. Sodium nitroprusside, ninhydrine E. Silver nitrate, sodium nitroprusside 59. Choose the chemical name of cocarboxylase: A. 3,7-dimethylxanthine B. Menthol ester of isovaleric acid C. Stearic ester of laevomycetin D. *Hydrochloride of thiamine diphosphate ether E. Ethyl ester of p-aminobenzoic acid 60. Cyanocobalamin is used in medical practice for the treatment of: A. Schizophrenia B. *Anemia C. Allergy D. Cold diseases E. Radiculitis 61. What reagents can be used for the detection of chloride ions in the thiamine hydrochloride molecule? A. K3[Fe(CN)6], NaOH, butyl alcohol B. *K2Cr2O7, H2SO4, diphenylcarbazide C. NaNO3, HCl, -naphthol alkaline solution D. K2Cr2O7, chloroform E. Sodium nitroprusside, KOH 62. Antianemic action of cyanocobalamine is cased due to the presence in its structure molecule of: A. *5,6-dimethylbenzimidazole B. Cobalt C. Ribofuranose D. Corrine E. Cyano-group 63. Folic acid gives reactions with salts of heard metals due to its properties: A. Basic B. *Acidic C. Amphoteric D. Oxidative E. Reductive 64. Thiamine hydrobromide is a vitamin preparation, in the medical practice it is used as vitamin: A. В5 B. В2 C. В6 D. *В1 E. В3 65. What compound has chemical name hydrochloride of thiamine diphosphate ether? A. Thiamine hydrochloride B. Pyridoxine hydrochloride C. Riboflavin D. Cyanocobalamin E. *Cocarboxylase 66. Choose the method of riboflavin assay in the substance: A. Acidimetry in aqueous environment B. Alkalimetry in aqueous environment C. *Alkalimetry by the substitute D. Permanganatometry E. Iodometry 67. Analyst conducts identification of the folic acid by the reaction with: A. *Salts of heard metals B. Salts of alkaline metals C. Marcy reagent D. Hydrochloric acid E. Oxides of heard metals 68. Analyst conducts assay of thiamine hydrobromide by argentometry (Fayanse method). What indicator (1) is used? What is the equivalent mass of thiamine hydrobromide (2)? A. 1–methyl orange, 2–М.m. B. 1–potassium chromate, 2 – 1/2 М.m. C. 1–bromthymol blue, 2 – М.m. D. *1–bromthymol blue, 2 – 1/2 М.m. E. 1–iron-ammonium alums, 2–М.м 69. What is the molecular mass of thiamine hydrobromide equivalent at it’s quantitative determination by acidimetry in non-aqueous medium according to SPhU? A. М.m. B. *М.m./2 C. М.m./4 D. М.m./8 E. 2 М.m. 70. Choose medical form of thiamine hydrochloride: A. Powder B. Ointment C. Aerosol D. *Tablets E. Suppositories 71. Folic acid by its chemical structure belongs to vitamins derivatives of: A. Purine B. Piperidine C. Pyridine D. *Pterin E. Pyrazole 72. What reagents can be used to identify thiamine hydrochloride? A. *K3[Fe(CN)6], NaOH, butyl alcohol B. AgNO3, HNO3, NH4OH C. NaNO3, HCl, -naphthol alkaline solution D. K2Cr2O7, chloroform E. Sodium nitroprusside, KOH 73. Thiamine hydrobromihe is used in medical practice as? A. Antiseptic B. Antispasmodic C. For the treatment of the urethra dysfunction D. *For the treatment of nervous system diseases E. For the diatheses treatment 74. Choose medical form of cocarboxylase? A. *Powder for parenteral insertion B. Powdering C. Powder for per oral insertion D. Tablets E. Injection solutions 75. Assay of the folic acid according to SPhU is conducted by the following method: A. Acidimetry in non-aqueous solution B. Liquid chromatography C. *Photocolorimetry D. Fluorimetry E. Alkalimetry in non-aqueous solution 76. Cyanocobalamin is a vitamin preparation, in the medical practice it is used as vitamin: A. В5 B. В2 C. В6 D. В1 E. *В12 77. There are two heterocycles in the cocarboxylase molecule: A. Pyrimidine, pyrrolidine B. Thiazole, thiazilidine C. *Pyrimidine, thiazole D. Thyazole, pyridine E. Pyridine, piperidine 78. The main structural parts of vitamin В12 molecule are: A. *5,6-dimethylbenzimidazole, purine B. Purine, corrine C. Corrine, 5,6-dimethylbenzimidazole D. Tropine, triazole E. Triazole, purine 79. What medical drug has the following structural formula? CH2OH H OH O O OH OH A. Nicotinic acid B. *Ascorbic acid C. Ergocalciferol D. Pantothenic acid E. Pangamic acid 80. What medical drug has the following structural formula? A. B. C. D. Calcium lactate Calcium citrate *Calcium pangamate Calcium pantothenate E. Calcium gluconate 81. What medical drug has the following structural formula? A. *Calcium pantothenate B. Calcium lactate C. Calcium citrate D. Calcium pangamate E. Calcium gluconate 82. What medical drug has the following structural formula? A. Rutin B. Tocopherol acetate C. Ergocalciferol D. Cianocobalamin E. *Retinol acetate 83. What medical drug has the following structural formula? A. Rutin B. Tocopherol acetate C. Cholecalciferol D. *Ergocalciferol E. Retinol acetate 84. What medical drug has the following structural formula? A. *Cholecalciferol B. Rutin C. Tocopherol acetate D. Ergocalciferol E. Retinol acetate 85. What medical drug has the following structural formula? O CH3 SO3Na * 3 H2O O A. Nicotinic acid B. *Vikasol C. Rutin D. Tocopherol E. Pyridoxine 86. What medical drug has the following structural formula? A. Rutin B. Vikasol C. *Tocopherol acetate D. Ergocalciferol E. Retinol acetate 87. What medical drug has the following structural formula? A. *Rutine B. Vikasol C. Tocopherol acetate D. Ergocalciferol E. Retinol acetate 88. What medical drug has the following structural formula? N COOH A. Rutin B. Tocopherol acetate C. Vikasol D. Ascorbic acid E. *Nicotinic acid 89. What medical drug has the following structural formula? A. Rutin B. Tocopherol acetate C. Nicotinic acid D. *Nicotinamide E. Vikasol 90. What medical drug has the following structural formula? A. *Pyridoxine hydrochloride B. Rutin C. Tocopherol acetate D. Thiamine hydrochloride E. Nicotinamide 91. What medical drug has the following structural formula? A. Pyridoxine hydrochloride B. *Thiamine hydrochloride C. Riboflavin D. Cianocobalamin E. Cocarboxylase 92. What medical drug has the following structural formula? A. Pyridoxine hydrochloride B. Thiamine hydrochloride C. *Cocarboxylase D. Riboflavin E. Cianocobalamin 93. What medical drug has the following structural formula? A. *Riboflavin B. Pyridoxine hydrochloride C. Thiamine hydrochloride D. Cocarboxylase E. Folic acid 94. What medical drug has the following structural formula? A. Riboflavin B. Cocarboxylase C. Cianocobalamin D. Thiamine hydrochloride E. *Folic acid 95. Steroid cycle in the molecules of cardiac glycosides is revealed by the reaction of: A. *Lieberman - Burhardt B. Legal C. Raymond D. Baljet E. Keller-Kilian 96. Pentamerous lactone cycle in the molecules of cardiac glycosides is revealed by the reaction of: A. Raymond B. *Legal C. Lieberman - Burhardt D. Keller-Kilian E. Baljet 97. Source of obtaining cardiac glycosides are different types of: A. Belladonna B. Poppy C. *Digitalis D. Hemp E. Ephedrine 98. Quantitative determination of cardiac glycosides according to the procedures DF X is carried out by the method of: A. Photocolorimetry B. Acidimetry C. Infrared spectroscopy D. Alkalimetry E. *Biological method 99. What monosaccharide is nonspecific for cardiac glycosides? A. B. C. D. E. Digitoxose D-cymarose L-rhamnose Oleandroze *Fructose 100. The aglycone structure of the cardiac glycosides, which are called cardenolides, is formed of such lactone cycle: A. *Pentamerous B. 6-membered C. Heptatomic D. 4-membered E. Octatomic 101. Bufadienolides are the part of: A. Digitalis B. *Hellebore C. Adonis D. Lily of the valley E. Strophanthus 102. 2-deoxysaccharides in the molecule of cardiac glycosides is revealed by the reaction of: A. Legalov B. *Pezets C. Raymond D. Baleta E. Lieberman - Burhardt 103. Which of the saccharides is included in the structure of the ouabain molecule? A. Lactose B. Digitoxose C. D-Cymarose D. *L-Rhamnose E. D-Oleandroze 104. Aglycone in the celanidum molecule is : A. Strofantidine B. Gitoxigenin C. Digitoxigenin D. *Digoxigenine E. Oleandrogenine 105. The bearer of the biological activity in the cardiac glycosides is: A. Saccharic part B. Pentamerous lactone cycle C. *Aglycone D. Radical in the position of the 10th aglycone E. OH-group in the position of the 14th aglycone 106. Six-membered lactone cycle in the molecule of cardiac glycosides may be detected with a solution: A. FeCl3 B. H2SO4 C. AlCl3 D. *SbCl3 E. CuSO4 107. Steroid cycle in the molecules of cardiac glycosides is revealed by the reaction of: A. *Rosenheim B. C. D. E. Legalov Keller-Kilian Pezets Balet 108. Pentamerous lactone cycle in the molecules of cardiac glycosides is revealed by the reaction of: A. Lieberman-Burhardt B. *Raymond C. Rosenheim D. Keller-Kilian E. Pezets 109. 2-deoxysaccharides in the molecule of cardiac glycosides is revealed by the reaction of: A. Legalov B. Raymond C. *Pezets D. Rosenheim E. Lieberman-Burhardt 110. 1According to their chemical structure cardiac glycosides belong to: A. Heterocyclic carboxylic acids B. Aromatic amines C. *Esters D. Ethers E. Polyhydric alcohols 111. Cardiac glycosides are extracted from various plants, one of which is: A. Belladonna B. Snakewood (Rauvolfia serpentina) C. Senecio platyphyllos D. *Spring Adonis(Adonis vernalis) E. Henbane (Hyoscyamus niger L) 112. Which of the saccharides does not belong to the cardiac glycosides structure? A. *Lactose B. Digitoxose C. D-cymarose D. L-rhamnose E. D-oleandroze 113. Bufadienolidy are the part of: A. Digitalis B. Adonis C. Lily of the valley D. *Sea onion (Urginea maritima) E. Strophanthus 114. Saccharic component, which is attached at position 3 to the cardiac glycoside aglycone, affects: A. Medical product form B. *The duration of drug action C. Directions for use D. Specific action of cardiac glycosides E. Side effects 115. Cardiac glycosides of the cardenolide group include in their molecule: A. Steroid cycle B. Double bond between C atoms C. Triple bond between C atoms D. Six-membered lactone cycle E. *Pentamerous lactone cycle 116. Quantitative determination of cardiac glycosides is carried out by the method of: A. Photocolorimetry B. Acidimetry C. *UV- spectroscopy D. Alkalimetry E. Precipitation titration 117. Cardiac glycosides genins are derived from: A. Cyclohexane B. Cholesterol C. *Cyclopentaneperhydrophenanthrene D. Adrostan E. Ergocalciferol 118. In the digitoxin molecule the aglycone is: A. Strophantidine B. Gitoksigenine C. *Digitoxigenin D. Digoxigenine E. Oleandrogenine 119. Cardiac glycosides aglycones are the derivatives of: A. Cholesterol B. Steranes C. *Cyclopentaneperhydrophenanthrene D. Androstane E. Pregnenolone 120. Pentamerous lactone cycle in the cardiac glycosides molecule is revealed by the reaction of: A. *Raymond B. Sakagush C. Lugol D. Ovchinnikov E. Rosenkheim 121. Steroid cycle in the structure of cardiac glycosides is revealed by the reaction of: A. Legalov B. Raymond C. Balet D. *Lieberman-Burhardt E. Keller-Kilian 122. Aglycone in the digoxin molecule is: A. Strophantidine B. Gitoksigenine C. Digitoxigenin D. *Digoxigenine E. Oleandrogenine 123. Konvalyatoksin the medical product of cardiac glycosides is extracted from such plant: A. Strophanthus Combe B. Strophanthus gratus C. *Convallaria majalis D. Erysimum diffuse E. Digitalis lanata 124. Cardenolides are identified by the maximum absorption at = 220 nm, comparing with the standard sample of preparation. Specify which physicochemical method is used then A. Refractometry B. Fluorometry C. Polarimetry D. *Spectrophotometry E. Polarography 125. Saccharid part in the cardiac glycosides molecules may be detected after acid hydrolysis by the reaction of: A. *Formation of silver mirror B. Dragendorf reagent C. Lieberman-Burhardt reagent D. Pezets reagent E. Schiff 126. The drug ouabain is also known as: A. *Strophanthin-G B. Strophanthin-K C. Korglikon D. Adonisid E. Kardiovalen 127. Saccharic part of the digitalis secondary glycosides consists of three molecules: A. D-Glucose B. *Digitoxose C. D-Cymarose D. L-Rhamnose E. D-Oleandroze 128. By the chemical structure glucose is related to: A. Polysaccharides B. Disaccharides C. *Monosaccharides D. Ketopentose E. Aldopentose 129. Indicate starch formula: A. C12H22O11 B. C5H10O5 C. *(C6H10O5)n D. C6H14O7 E. C6H12O7 130. Sucrose aqueous solution heating generates: A. Beet sugar B. Cane sugar C. Lactose D. *Invert sugar E. Tautorotation sugar 131. What analytical reaction effect is observed during the interaction of glucose with the Feling reagent? A. Crimson-violet formations B. A yellow sediment C. Formations of violet colour D. *Formations of red sediment 132. 133. 134. 135. 136. 137. 138. 139. 140. E. CO2 bubbles separation with the subsequent identification One of the methods of glucose quantitative determination is the method of: A. Acidimetry B. Alkalimetry C. *Iodinometry D. Permanganatometry E. Complexometry Which of the following saccharides relates to non-restorable glycosacchara: A. Glucose B. Lactose C. Maltose D. *Sucrose E. Fructose Which molecule property results the optical activity of the glucose solution? A. The tautomery characteristic B. Changing of the solution refraction angle C. *The ability to rotate the polarized light plane as it passes through the solution D. Inversion phenomenon E. Changes in the EMF solution By its chemical structure the starch belongs to the group of: A. Disaccharides B. Monosaccharides C. Proteoglycans D. *Polysaccharides E. Peptidoglycans What chemical compound when it’s heated forms caramel? A. Glucose B. Lactose C. Starch D. *Sucrose E. Amylose In medical practice sucrose is used: A. For the treatment of shock B. For trituration manufacturing C. *For the manufacture of syrups D. For collapse E. For the treatment of radiation sickness Which hydrocarbon belongs to the hexose class? A. Starch B. D-Ribose C. Sucrose D. Lactose E. *D-glucose Indicate the sucrose formula: A. C5H10O5 B. C5H12O5 C. C6H12O6 D. (C6H10O5)n E. *C12H22O11 What monosaccharide is in the lactose molecule? A. D-(+)-mannose B. D-(-)-ribose C. *D-galactose D. D-fructose E. L-fucose 141. What glucose properties determine the reaction with ammonia solution of silver nitrate: A. The ability to rotate the polarization plane of polarized light B. *Regenerative C. Oxidative D. The ability to polymerization E. The ability to absorb light in the UV-area spectrum 142. Pharmacist-analyst conducts quantitative determination of glucose by the iodinometry method. What is the molar mass of equivalent? A. 1/3 М.m. B. *¼ М.m. C. ½ М. m. D. М.m. E. 1,5 M.m. 143. What of the following succharides is characterized by the inversion phenomenon? A. Maltose B. Cellobiose C. Lactose D. *Sucrose E. Glucose 144. The interaction of glucose with mineral acids at time of heating forms: A. Furfural B. Acetone C. Benzol D. *Methylolfurfural E. Toluene 145. Determine the type of reaction which is used for the glucose identification: A. Recovery B. Polymerization C. Polycondensation D. *Oxidation E. Expansions 146. Angle measurement of the 10% glucose solution conversion is carried out by: A. UV-spectrophotometer B. Refractometer C. Infrared spectrophotometer D. *Polarimeter E. Photoelectrocolorimeter 147. Sucrose is used in medical practice: A. As a means of enveloping B. To slow down the absorption of drugs C. For the trituration preparation D. Antidote to heavy metal poisoning E. *Auxiliary for the preparation of medicines 148. Due to its chemical structure glucose belongs to: A. Aldopentoses B. Ketopentoses C. *Aldogeksoses D. Desoxisaccharides E. Ketogexoses 149. Indicate the lactose formula: A. C5H10O5 B. C5H12O5 C. C6H12O6 D. *C12H22O11 E. (C6H10O5)n 150. Which monosaccharide is a component of sucrose? A. alpha-D-galactose B. Amylose C. *beta-D-fructose D. Amylopectin E. D-digitoxose 151. In the interaction with which reagent glucose constitutes osasone? A. Nessler reagent B. Tollens reagent C. Phenylhydrazine D. *Sorrel acid E. Feling reagent 152. One of the glucose identification reactions held by rapid analysis method is the interaction with: A. Sodium to sodium, weak chloride acid B. Alkaline beta-naphthol solution C. Thorium nitrate D. *Thymol, concentrated sulphate acid E. Milon basis 153. With what reagent solution lactose aqueous solution while heated is painted in red? A. Vanillin B. Dimethylaminobenzaldehyde C. Sodium nitroprusside D. Ammoniac E. *Resorcin 154. Glucose is characterized by the phenomenon of: A. Inversion B. Dismutation C. *Polymerization D. Gelatinization E. Tautorotation 155. What glucose molecule fragment conditioned its property to rotate the polarized light plane? A. Aldehyde group B. Alcoholic hydroxyls C. *Chirality centers D. Carbon backbone chain E. Tautomeric groups 156. One of the lactose identification reactions is the interaction with the reagent of: A. Marky B. *Fisher C. Copper-tartrate D. Dragendorf E. Molish 157. The quantitative content of glucose in solutions for injection is carried out by: A. B. C. D. E. UV-spektoskopy Refractometry *Photoelectrocolorimetry Infared spectroscopy Potentiometry 158. On the torpenoid molecule base is the hydrocarbon of: A. Butene B. Butadiene C. *Isoprene D. Pentene E. Isopentene 159. Chemical name of (1RS, 4SR) -1,7,7-Trimethylbicyclic [2,2,1] heptane-2-ol corresponds to the formula of: A. Validol B. Terpinehydrate C. Sulfocamphocaine D. Menthol E. *Camphor 160. Quantitative determination of validol in accordance with AND is carried out by the method of: A. Acidimetry, back titration B. *Alkalimetry, back titration C. Photocolorimetry D. Argentometry after Folgard E. Argentometry after Fajans 161. Bromide-ion in bromcamphor after previous mineralization displays the interaction with: A. Ironammoniac alum B. Ammonium thiocyanate C. Hydroxylamine hydrochloride D. Sodium hydroxide and zinc dust at the process of heating E. *Chloramine, chloride acid under chloroform 162. Molar mass of menthol equivalent at its quantitative determination by the method of acetylation is: A. М.m / 8 B. М.m / 4 C. М.m / 2 D. *М.m. E. М.m / 3 163. In the interaction of what drug with the concentrated sulfate acid one feels the smell of terpineol? A. Camphora B. *Terpinehydrate C. Bromcamphor D. Menthol E. Validol 164. What reagent may detect sulfogroup in the sulfocamphoric acid molecules after its mineralization with a mixture of Na2CO3 and NaNO3? A. Pb(CH3COO)2 B. Na2CO3 C. KOH D. Na3PO4 E. *BaCl2 165. The starting compounds for Validol are: A. Terpinehydrate, isovaleric acid B. *Menthol, isovaleric acid C. Camphor, valeric acid D. Phenol, isovaleric acid E. Thymol, valeric acid 166. Specify the reagents with the help of which one can realize the reaction of menthol identification: A. *Dinitrobenzoylchloride, vanillin in concentrated H2SO4 B. Hydroxylamine hydrochloride C. Benzaldehyde, concentrated H2SO4 D. Ammonium molybdate E. Isopropylchloride 167. Medical product corvalol is used to treat: A. Allergic diseases B. Sexually transmitted diseases C. *Neuroses, tachycardia D. Dermatitis E. Chronic polyarthritis 168. Chemical name of 2-Methylbutadiene-1, 3 is: A. Butene B. Propene C. Pentene D. *Isoprene E. Isoamylene 169. Structural formula of camphor corresponds to the following chemical name: A. N-Menthadione - 1,8 - hydrate B. 2-Methylbutadiene-1, 3 C. CMethylisopropylcyclohexane D. (1RS, 2SR, 5RS) - 5-Methyl - 2 - (1 - Methylethyl) Cyclohexanol E. *(1RS, 4SR) - 1,7,7 - Trimethylbicyclo [2,2,1] heptane-2- ol 170. At the quantitative determination of validol according to AND by the alkalimetry method, back titration, the molar mass of its equivalent is: A. *М.m. B. М.m / 2 C. М.m / 4 D. М.m / 8 E. 2 М.m. 171. Specify the components of drug sulfocamphocaine. A. Sulfocamphoric acid, menthol B. Sulfocamphoric acid, camphor C. Sulphate acid, novocaine base D. *Sulfocamphoric acid, novocaine base E. Sulfocamphoric acid, bromcamphor 172. With the help of what reagent one can identify menthol: A. 2,4 - Dinitrophenylhydrazine B. 2,4 - Dinitrochlorbenzene C. *Dinitrobenzoylchloride D. Hydrazine sulphate E. Hydroxylamine hydrochloride 173. To what group of derivative organic compounds belongs terpinehydrate? A. B. C. D. E. Bicyclic terpenoids Cycloalkanes Aromatics Hormones *Monocyclic terpenoids 174. What reagent can detect ketogroup in the bromcamphor molecule? A. Iron (III) chloride B. *Hydroxylamine hydrochloride C. Formaldehyde D. Benzenelsulfochloride E. Concentrated nitrate acid 175. What physical constant determinations are used to identify the sulfocamphor acid? A. Electricity B. *Melting temperature C. Boiling temperature D. Fracture index E. Light absorption coefficient 176. L-Camphor is obtained by the method of: A. V. E. Tishchenko B. D. M. Mendeleyev C. *N. V. Vershinin D. M. M. Zinin E. O. M. Butlerov 177. Menthol is a part of such combined preparations: A. *Pektusin, boromenthol, menovazin B. Pertusin, bom-benge ointment C. Pektosol, Lasar dope D. Dry linctus E. Validol, gerovital 178. Monocyclic terpenoids drugs are derived from: A. Camphene B. Menthol C. *Mentane D. Camphane E. Camphor 179. Starting material to obtain menthol by the synthetic method is: A. Toluene B. Benzene C. *m-Cresol D. Pyrocatechol E. Pyrogalol 180. Menthol in validol is identified according to the requirements of the AND by interaction with: A. FeCl3 solution B. *Vanillin solution in concentrated H2SO4 C. Concentrated sulphate acid D. Hydroxylamine hydrochloride E. Nesler's reagent 181. The bromcamphor quantitative determination after previous mineralization according to the AND requirements is held by the method of argentometry after: A. Fajans B. Mor C. *Folgard D. Koltgof E. Fajans-Khodakov 182. Chemical name of medical product terpinehydrate is: A. *N-Mentadiol-1 ,8-hydrate B. (1RS, 2SR, 5RS)-5-Methyl-2-(1-Methylethyl) Cyclohexane C. (1RS, 4SR) -1,4,7-Trimethylbicyclo [2,2,1] Heptane-2- ol D. D-(+)-Glucopyranose E. 4-L-D-Galactosepyranose 183. 182. Two asymmetric carbon atoms in the camphor molecule define its: A. Easy water solubility B. The ability to absorb visible light C. Easy solubility in alcohol D. *The ability to rotate the plane of polarized light E. Poor water solubility 184. What titrant is used in quantitative determination of novocaine in drug sulfocamfokaine? A. Potassium permanganate B. Sodium hydroxide C. Hydrogen peroxide D. *Sodium nitrite E. Cerium sulphate 185. The constituents of the drug validol are: A. Camphor, menthol B. Camphor, menthyl esther of isovaleric acid C. Menthol, bromcamphor D. Menthyl esther of isovaleric acid, sulfocamphoric acid E. *Menthol solution, menthyl esther of isovaleric acid 186. Which indicator is used to fix the equivalence point in quantifying validol according to the requirements of the AND? A. Cerium (IV) sulphate B. Starch C. Feroine D. *Phenolphthalein E. Methyl red 187. Validol is used in medical practice for the treatment of: A. *Stenocardia angina prectoris, neuroses. B. Diseases of gastrointestinal tract C. Dermatitis D. Allergic diseases E. Epilepsy 188. Chemical name of 2-Chlor-10-(3'-Dimethylaminopropyl)-Phenothiazine Hydrochloride is: A. Trifluoroperazine hydrochloride B. Promethazine hydrochloride C. Promazine hydrochloride D. *Chlorpromazine hydrochloride E. Perphenazine hydrochloride 189. Medical product medazepam corresponds to the following chemical name: A. 7-Brom-1 ,3-Dihydro-5-(o-Chlorophenyl)-1H-1 ,4-Benzodiazepin-2 B. 7-Nitro-1 ,3-Dihydro-5-Phenyl-2H-1 ,4-Benzodiazepin-2 C. 7-Chlor-1 ,3-Dihydro-3-Hydroxy-5-Phenyl-2H-1 ,4-Benzodiazepin-2 D. 7-Chlor-1 ,3-Dihydro-1-Methyl-5-Phenyl-1H-1 ,4-Benzodiazepin-2 E. *7-Chlor-2 ,3-Dihydro-1-Methyl-5-Phenyl-1H-1 ,4-Benzodiazepine 190. Promethazine hydrochloride corresponds to the following commercial name: A. Triphtazine B. Aminazine C. C.Moracizine hydrochloride D. *Diprazine E. Diphenhydramine hydrochloride 191. What analytical effect one may observe at the interaction of trifluoroperazine chloride with bromine water: A. The solution is dark cherry coloured B. *The solution is crimson C. The solution is painted in red D. Formation of white sediment E. The solution turns light violet 192. Fusion of phenazepame with sodium hydroxide leads to the destruction of the molecular bond and isolation of: A. Chlorine B. *Ammonia C. Bromine D. Urea E. Methylamine 193. According to the requirements of AND quantification of trifluoroperazine hydrochloride substance is held by the method of acidimetry in non-aqueous medium. What is the equivalent mass of the drug? A. М.m /8 B. М.m/4 C. 2 М.m D. М.m E. *М.m/2 194. Phenazepame ability to recover is in the basis of quantitative determination of it by the method of: A. HPLC B. Polarimetry C. *Polarography D. Potentiometry E. UV-spectroscopy 195. The presence of nitrogroup in the nitrozepame structure can be confirmed by the reaction of its alcoholic solution with : A. Sodium chloride B. Acetate acid C. Sulphate acid D. Iron (III) chloride E. *Sodium hydroxide 196. Commercial name mezapame corresponds to medicinal product: A. Diazepame B. Oxazepame C. Nitrozepame D. Chlordiazepoxide E. *Medazepame 197. One of the methods to quantify drugs, phenothiazine derivatives, is the alkalimetry method in the aqueous medium. In the presence of what solvent occurs the titration? A. B. C. D. E. Acetone Benzene *Chlorophaite Methyl alcohol Dimethylformamide (DMF) 198. Chemical name of 10 - (3'-Dimethylaminopropyl)-Phenothiazine hydrochloride corresponds to: A. Chlorpromazine hydrochloride B. Promethazine hydrochloride C. Trifluorineperazine hydrochloride D. *Propazine E. Ethaperazine 199. Medicinal product fenazepame corresponds to the following chemical name: A. *7-Brom-1 ,3-Dihydro-5-(o-Chlorophenyl)-1H-1 ,4-Benzodiazephin-2 B. 7-Nitro-1 ,3-Dihydro-5-Phenyl-2H-1 ,4-Benzodiazepin-2 C. 7-Chloro-1 ,3-Dihydro-3-Hydroxy-5-Phenyl-2H-1 ,4-Benzodiazepin-2 D. 7-Chloro-1 ,3-Dihydro-1-Methyl-5-Phenyl-1H-1 ,4-Benzodiazepin-2 E. 7-Chloro-2 ,3-Dihydro-1-Methyl-5-Phenyl-1H-1 ,4-Benzodiazepine 200. Commercial name of trifluorineperazine hydrochloride is: A. Aminazine B. Diprazine C. Ftorafur D. Ftoracil E. *Triphtazine 201. Which of the following compounds is the source for the chlorpromazine synthesis? A. N-Nitrophenol B. Anisidine C. 2,4-Dinitrochlorobenzene D. *2-Chlorphenothiazine E. Chlorobenzene 202. Specific reaction after pyrolysis of benzodiazepine derivatives is the formation of the alloy coloured: A. *Green B. Violet C. Red D. Blue E. Black 203. According to the requirements of GFU quantification of promethazine hydrochloride is carried out by the alkalimetry method in mixture of alcohol and 0.01 M of chloride acid solution. Which method fixes endpoint of equivalence? A. Polarimetry B. Ion exchange chromatography C. UV-spectrophotometry D. *Potentiometry E. Visual assessment 204. What is the molecular mass of diazepame equivalent in the quantitative determination of it by the acidimetry method in non-aqueous medium: A. 1/4 М m B. 2 М m C. 1/5 М m D. 1/2 М m E. *М m 205. Bromide ions are defined in the solution obtained after boiling fenazepame with a sodium hydroxide solution, by the following reagents: A. Argentum chloride, nitrate acid B. Acetate acid, discolored fuchsin C. Copper sulphate, sulphate acid D. Iron (III) chloride, chloride acid E. *Chloride acid, chloramine, chloroform 206. Commercial name of elenium corresponds to the medicinal product: A. Diazepame B. Oxazepame C. *Chlordiazepoxide D. Nitrazepame E. Medazepame 207. Medicines, benzodiazepine derivatives, are used in medical practice as: A. Anaesthetic B. Narcotic analgesics C. *Tranquilizers D. Non steroidal anti-inflammatory drugs (NSAIDs) E. Non-narcotic analgesics 208. Chemical name of (2RS)-N, N-Dimethyl-1-(10H-Phenothiazine-10-ol) Propane-2Amine Hydrochloride сorresponds to: A. Chlorpromazine hydrochloride B. Trifluorineperazine hydrochloride C. Ethaperazine D. Ethmozine E. *Promethazine hydrochloride 209. Medical product chlordiazepoxide corresponds to the following chemical name: A. *7-Chloro-2-Methylamino-5-Phenyl-3H-1 ,4-Benzodiazepin-4-Oxide B. 7-Nitro-1 ,3-Dihydro-5-Phenyl-2H-1 ,4-Benzodiazepin-2 C. 7-Chloro-1 ,3-Dihydro-3-Hydroxy-5-Phenyl-2H-1 ,4-Benzodiazepin-2 D. 7-Chloro-1 ,3-Dihydro-1-Methyl-5-Phenyl-1H-1 ,4-Benzodiazepin-2 E. 7-chloro-2 ,3-dihydro-1-methyl-5-phenyl-1H-1 ,4-benzodiazepine 210. Commercial name of chlorpromazine hydrochloride is: A. Ethmozine B. Ethaperazine C. *Chlorpromazine D. Promethazine E. Chlorpropamide 211. What properties of drugs, phenothiazine derivatives, are used to identify them? A. Restoration ability B. Hydrogenation ability C. Dehydrogenation ability D. Polymerization ability E. *Oxidation ability 212. 211. Positive reaction of drugs, benzodiazepine derivatives, with general alkaloid sedimentation reagents determines availability of such elements in their structure: A. Nitrogen atom in position 1 B. *Nitrogen atom in position 4 C. Substitute in position 7 D. Benzene nucleus E. Lactam group 213. What method is used to quantify Nitrogen after sulphate P acid mineralization in the molecules of fenthiazine derivatives drugs? A. Sanger-Black B. Bugo-Thiele C. Marsh D. *Kjeldal E. Vitali-Moren 214. What is the molecular mass of the oxazepam equivalent in the quantitative determination of it by the acidimetry method in non-aqueous medium: A. *М m B. 1/4 М m C. 2 М m D. 1/5 М m E. 1/2 М m 215. Bromide ions are determined in the solution obtained after boiling fenazepame with a sodium hydroxide solution,by the following reagents: A. Silver chloride, nitrate acid B. *Lead (IV) oxide, acetate acid, discolored fuchsin C. Copper sulphate, sulphate acid D. Iron (III) chloride, chloride acid E. Iodine, chloroform 216. Commercial name of chlozepide is: A. Diazepame B. Oxazepame C. Nitrazepame D. *Chlordiazepoxide E. Medazepame 217. Nitrogroup in the nitrazepame structure may be confirmed by the reaction of an alcohol solution with: A. Sodium chloride B. Acetate acid C. Sulphate acid D. Iron (III) chloride E. *Sodium hydroxide 218. What medical product corresponds to the structural formula? O O CH3 H CH3 H H CH3 H O O CH3 O O CH3 O O OH OH A. Digoxin OH OH H OH B. C. D. E. 219. *Digitoxin Ouabain Convallatoxin Celanidum What medical product corresponds to the structural formula? O O OH H CH3 H CH3 H H CH3 OH H O O H CH3 O O OH CH3 O O OH OH OH A. B. C. D. E. 220. Ouabain Digitoxin *Digoxin Convallatoxin Celanidum What medical product corresponds to the structural formula? O O H HO HO H H H H OH OH O O OH A. B. C. D. E. H OH * 8 H2O CH3 221. CH3 HO OH *Ouabain Digitoxin Digoxin Convallatoxin Celanidum What medical product corresponds to the structural formula? O O CH3 H O C H H OH OH O O OH CH3 OH A. B. C. D. E. 222. OH Ouabain Digitoxin Digoxin *Convallatoxin Celanidum What medical product corresponds to the structural formula? O O OH CH3 CH3 H H OH CH3 O O CH3 O OH CH3 O OH CH2OH O OCOCH3 HO OH OH A. B. C. D. E. 223. Ouabain Digitoxin Digoxin Convallatoxin *Celanidum What medical product corresponds to the structural formula? CH2OH O H H OH H H OH OH H A. B. C. D. E. 224. OH Lactose Galactose *Glucose Sucrose Rhamnose What medical product corresponds to the structural formula? CH2OH O OH H OH H H OH H H A. B. C. D. E. 225. OH D-glucose Lactose Digitoxose *D-galactose Sucrose What medical product corresponds to the structural formula? H CH2OH O OH H OH A. B. C. D. E. 226. H OH H H H H OH O H H OH H O CH2OH OH Glucose Galactose Pulp Sucrose *Lactose What medical product corresponds to the structural formula? CH2OH O H H OH H CH2OH H H O H OH OH H O OH H A. Glucose B. Galactose OH CH2OH 227. C. Pulp D. Lactose E. *Sucrose What medical product corresponds to the structural formula? NH2 * HCl A. B. C. D. E. 228. Rimantadine *Midantan Glyudantan Validol Tropatsin (Diphenyltropine) What medical product corresponds to the structural formula? COOH NH O H A. B. C. D. E. 229. H H OH OH H H OH Rimantadine Midantan *Glyudantan Validol Tropatsin(Diphenyltropine) What medical product corresponds to the structural formula? H C CH3 * HCl NH2 A. B. C. D. E. 230. *Rimantadine Midantan Glyudantan Validol Tropatsin(Diphenyltropine) What medical product corresponds to the structural formula? CH3 OH CH H 3C A. B. C. D. Camphor Midantan Terpingidrat Validol CH3 231. E. *Menthol What medical product corresponds to the structural formula? CH3 CH3 + O OH O CH H3C A. B. C. D. E. 232. CH CH3 H3C C CH3 C H2 CH CH3 CH3 Camphor Medantan Terpingidrat *Validol Tropatsin(Diphenyltropine) What medical product corresponds to the structural formula? H 3C OH * H2O H 3C A. B. C. D. E. 233. CH3 OH *Terpingidrat Medantan Glyudantan Validol Tropatsin(Diphenyltropine) What medical product corresponds to the structural formula? CH3 O H3 C A. B. C. D. E. 234. CH3 Validol Midantan *Camphor Menthol Tropatsin(Diphenyltropine) What medical product corresponds to the structural formula? CH3 O H3C CH3 Br A. B. C. D. E. 235. Sulfokamfokain *Bromcamfora Validol Midantan Boromentol What medical product corresponds to the structural formula? H2C SO2OH O H3C A. B. C. D. E. 236. CH3 * H2O Terpingidrat Sulfokamfokain *Sulfocamforic acid Validol Boromentol What medical product corresponds to the structural formula? S * HCl N Cl H2C C H2 C H2 N CH3 CH3 A. B. C. D. E. 237. Chlordiazepoxide *Chlorpromazine hydrochloride Promethazine hydrochloride Perphenazine hydrochloride Moracizine hydrochloride What medical product corresponds to the structural formula? S * HCl N H 2C H C N CH3 CH3 CH3 A. B. C. D. E. 238. Promazin hydrochloride Chlorpromazine hydrochloride *Promethazine hydrochloride Perphenazine hydrochloride Moracizine hydrochloride What medical product corresponds to the structural formula? S * HCl N H2C C H2 C H2 N CH3 CH3 A. B. C. D. E. 239. *Promazine hydrochloride Chlorpromazine hydrochloride Promethazine hydrochloride Perphenazine hydrochloride Moracizine hydrochloride What medical product corresponds to the structural formula? S * 2 HCl N Cl (CH2)3 A. B. C. D. E. 240. N N (CH2)2OH Promazine hydrochloride Chlorpromazine hydrochloride Promethazine hydrochloride *Perphenazine hydrochloride Moracizine hydrochloride What medical product corresponds to the structural formula? S * 2HCl N CF3 (CH2)3 A. B. C. D. E. 241. N N CH3 Promethazine hydrochloride Perphenazine hydrochloride Moracizine hydrochloride *Triftorperazine hydrochloride Chlorpromazine hydrochloride What medical product corresponds to the structural formula? S N H N O A. B. C. D. E. C Promethazine hydrochloride Perphenazine hydrochloride Chlorpromazine hydrochloride *Moracizine hydrochloride Levomepromazine (CH2)2 N O * HCl C OC2H5 O 242. What medical product corresponds to the structural formula? S * HCl N H 2C OCH3 CH3 H C C H2 N CH3 CH3 A. B. C. D. E. 243. Promethazine hydrochloride Perphenazine hydrochloride Chlorpromazine hydrochloride *Levomepromazine Chlordiazepoxide What medical product corresponds to the structural formula? S O NH C OC2H5 N C2H5 O A. B. C. D. E. 244. C C H2 C H2 * HCl N C2H5 *Etatsizin Etaperazin Elenium Chlorpromazine Diazepam What medical product corresponds to the structural formula? O H N N Br Cl A. B. C. D. E. 245. Diazepam Aminazine *Phenazepam Oxazepam Etatsizin What medical product corresponds to the structural formula? O H N O 2N N A. B. C. D. E. 246. Diazepam Phenazepam *Nitrazepam Propazin Aminazine What medical product corresponds to the structural formula? O H N OH N Cl A. B. C. D. E. 247. Diazepam Elenium *Oxazepam Phenazepam Aminazine What medical product corresponds to the structural formula? CH3 O N N Cl A. B. C. D. E. 248. Phenazepam Radedorm *Diazepam Oxazepam Aminazine What medical product corresponds to the structural formula? CH3 N Cl A. Diazepam B. Phenazepame C. *Mezapam N 249. D. Oxazepam E. Nitrazepam What medical product corresponds to the structural formula? HN CH3 N Cl N O A. B. C. D. E. Nitrazepam Propazin *Chlordiazepoxid Diazepam Aminazine 250. To the medical drugs of the alkalods’ group with exocyclic nitrogen atom: A. Atropine sulfate, quinine hydrochloride B. Scopolamine hydrobromide, pachicarpine hydroiodide C. *Ephedrine hydrochloride, spherophysine benzoate D. Morphine hydrochloride, codeine phosphate E. Strychnine nitrate, papaverine hydrochloride 251. Medical drug pachicarpine hydroiodide according to its chemical structure belongs to the derivatives of: A. Tropane B. Purine C. Indole D. Imidazole E. *Quinolysine 252. Determine the molecular mass of the ephedrine hydrochloride equivalent at its assay by acidimetry in non-aqueous environment: A. 1/4 М.m. B. 2 М.m. C. *М.m. D. 1/2 М.m. E. 1/5 М.m. 253. Platyphylline is extracted from the roots and grass of: A. Cytisus laburnum B. Thermopsis lanceolata C. Sophora pachycarpa D. *Senecio plathyphyllus E. Rauwolfia serpentina Benth 254. What reagent is proposed in SPhU to determine alkaloids? A. Marcy B. Erdman C. *Dragendorff D. Frede E. Wagner 255. What reaction can be used to determine guanine residue in spherophysine molecule? A. Heating with bromine water B. C. D. E. Heating with sulfate acid Vitali-Morin *Heating with sodium hydroxide With phenolphthalein 256. Assay of pilocarpine hydrochloride is conducted according to the AND requirements by the following method: A. Gravimetry B. Comlexonometry C. Nitritometry D. Acidimetry in aqueous environment E. *Acidimetry in non-aqueous environment 257. Barium is a specific admixture in the quinine hydrochloride. Barium can be determined with the solution of: A. Hydrochloric acid B. Nitrate acid C. Sodium hydroxide D. *Sulfate acid E. Iodine 258. Pilocarpine hydrochloride is used in the medical practice as: A. Anesthetic mean B. *Cholinomimetic mean C. Uterine muscular stimulant D. CNS stimulant E. Antitussive mean 259. Iodide-ion in the pachycarpine hydroiodide can be detected with the usage of the following reagents: A. *AgNO3, HNO3, NH4OH B. AgNO3, H2SO4, NH4OH C. AgNO3, H3PO4, NH4OH D. K2Cr2O7, H2SO4 E. K2Cr2O7, H2SO4, diphenylcarbazide 260. To the medical drugs from a group of alkaloids, imidazole derivatives, the following compound belongs: A. *Pilocarpine hydrochloride B. Atropine sulfate C. Ephedrine hydrochloride D. Strychnine nitrate E. Papaverine hydrochloride 261. The medical drug cytitone according to its chemical structure belongs to the derivatives of: A. Tropane B. Purine C. Indole D. Imidazole E. *Quinolysine 262. Which of the following drugs is responsible to the chemical name 1–guanidino–4– (isoamilene–1')–aminobutane dibenzoate? A. Physostigmine salicylate B. Caffeine sodium benzoate C. *Spherophysine benzoate D. Theobromine E. Cytisine 263. Pachicarpine isolated from the grass of: A. Cytisus laburnum B. Thermopsis lanceolata C. *Sophora pachycarpa D. Senecio plathyphyllus E. Rauwolfia serpentina Benth 264. What reagents can be used to identify chloride-ion the quinine hydrochloride molecule? A. *AgNO3, HNO3, NH4OH B. AgNO3, H2SO4, NH4OH C. AgNO3, H3PO4, NH4OH D. K2CrO4, H2SO4 E. K2Cr2O7, H2SO4, chloroform 265. A characteristic reaction for pilocarpine hydrochloride is a formation of: A. Shiff bases B. *Above chromic acids C. Azo-dye D. Peroxide compounds E. Iodoform 266. Determine the molecular mass of the quinine hydrochloride equivalent at its assay by bromatometry: A. 1/4 М. m. B. 2 М. m. C. М. m. D. *1/2 М. m. E. 1/5 М. m. 267. Senecephylline admixture in the platyphylline hydrotartrate can be determined by the adding of the following solution: A. Hydrochloric acid B. Nitrate acid C. Sodium hydroxide D. Sulfate acid E. *Ammonia 268. Ephedrine hydrochloride is used in the medical practice as: A. CNS stimulant B. Analgesic mean C. Mydriatic mean D. Local anesthetic mean E. *Vessels narrow, broncho-spreading 269. Bouchard reagent is a general precipitate reagent. It includes: A. *Sol. I2 in КI B. HgI2 + 2KI↔K2[HgI4] C. BI3+KI↔K[BI4] D. Sol. CdI2 in KI E. 5 % tannin solution 270. To the medical drugs from a group of alkaloids, pyrrolizidine derivatives, the following compound belong: A. Pilocarpine hydrochloride B. Atropine sulfate C. *Platyphylline hydrotartrate D. Strychnine nitrate E. Papaverine hydrochloride 271. Assay of cytisine is conducted according to the AND requirements by the following method: A. Argentometry by Folgard method B. Argentometry be Mor’s method C. *Acidimetry in aqueous environment D. Gravimetry E. Iodometry 272. Marcy reagent is a general alkaloid color reagent. It includes: A. Concentrated sulfate acid B. Concentrated sulfate and concentrated nitrate acid C. Ammonium molybdate in concentrated sulfate acid D. *formaldehyde solution in concentrated sulfate acid E. p-Dimethylaminobenzaldehyde in concentrated sulfate acid 273. Ephedrine is obtained from: A. Belladonna B. *Ephedra C. Vanillin D. Benzene E. Rauwolfia 274. Which of the following preparations does give taleyoquine test? A. Atropine sulfate B. *Quinine sulfate C. Ephedrine hydrochloride D. Cytisine E. Codeine 275. For the lactone cycle identification in the pilocarpine hydrochloride molecule the following reaction can be used: A. Vitali-Morin B. Taleyoquine formation C. *Legal D. Lughole E. Bouchard 276. Determine the molecular mass of the spherophysine benzoate equivalent at its assay by bromatometry: A. 1/4 М. m B. 2 М. m C. *1/2 М. m D. М. m E. 1/5 М. m 277. What reagents can be used to identify iodide-ion the pachycarpine hydroiodide molecule? A. *AgNO3, HNO3, NH4OH B. AgNO3, H2SO4, NH4OH C. AgNO3, H3PO4, NH4OH D. K2Cr2O7, H2SO4 E. K2Cr2O7, H2SO4, diphenylcarbazide 278. Spherophysine benzoate is used in the medical practice as: A. Expectorant mean B. Antitussive mean C. Antibacterial mean D. *Hypotensive mean E. Hypoglycemic mean 279. Medical drug cytitone is: A. a 0,5 % cytisine aqueous solution B. a 1 % cytisine alcoholic solution C. *a 0,15 % cytisine aqueous solution D. a 2 % solution of nicotinic acid E. a 40 % formaldehyde solution 280. Which of the following preparations has chemical name tropinic ester of diphenylacetic acid hydrochloride? A. Codeine B. Caffeine C. Proserin D. *Tropacine E. Cytisine 281. Determine the molecular mass of the atropine sulfate equivalent at its assay by alkalimetry in alcohol-chloroform environment: A. 1/4 М. m B. 2 М. m C. М. m D. *1/2 М. m E. 1/5 М. m 282. What medical drug does include papaverine hydrochloride? A. No-spa B. Analgin C. Adelphane D. *Papazol E. Citramone 283. Atropine sulfate is used in the medical practice as: A. Anesthetic mean B. *Cholinolytic mean C. Uterine muscular stimulant D. Emetic mean E. Antitussive mean 284. Which of the following preparations has chemical name 3,6 –dioxy–N-methyl-4,5– epoxymorphinene–7 trihydrate hydrochloride? A. Codeine phosphate B. Caffeine monohydrate C. Cocaine hydrochloride D. *Morphine hydrochloride E. Papaverine hydrochloride 285. What reagents can be used to identify phosphate-ion in the codeine phosphate molecule? A. *AgNO3, HNO3 B. AgNO3, H2SO4 C. AgNO3, NH3 D. K2Cr2O7, H2SO4 E. K2Cr2O7, HCl 286. Assay of apomorphine hydrochloride according to the AND requirements is conducted by the following method: A. Gravimetry B. Complexonometry C. Nitritometry D. *Acidimetry in non-aqueous environment E. Alaklimetry by the substitute 287. Morphine hydrochloride is used in the medical practice as: A. Anesthetic mean B. *Narcotic analgesic mean C. Uterine muscular stimulant D. Emetic mean E. Antitussive mean 288. To the alkaloids’ group medical drugs, morphinane derivatives, the following compound belongs: A. Physostigmine salicylate B. Strychnine nitrate C. *Codeine phosphate D. Ethylmorphine hydrochloride E. Caffeine monohydrate 289. What reagents can be used to identify chloride-ion the apomorphine hydrochloride molecule? A. *AgNO3, HNO3, NH4OH B. AgNO3, H2SO4, NH4OH C. AgNO3, H3PO4, NH4OH D. K2Cr2O7, H2SO4, chloroform E. K2Cr2O7, H2SO4, iodine 290. Assay of atropine sulfate according to the AND requirements is conducted by the following method: A. Gravimetry B. Complexonometry C. Nitritometry D. Acidimetry in aqueous environment E. *Acidimetry in non-aqueous environment 291. Drotaverine hydrochloride is the chemical name of the following spasmodic mean: A. Baralgine B. Papaverine C. Papazol D. *No-spa E. Spasmalgon 292. Which of the following preparations has chemical name 1–(3',4'–dimethoxybenzyl)– 6,7–dimethoxyisoquinoline hydrochloride: A. Quinine hydrochloride B. Ephedrine hydrochloride C. Cocaine hydrochloride D. Morphine hydrochloride E. *Papaverine hydrochloride 293. Assay of cocaine hydrochloride according to the AND requirements is conducted by the following method: A. *Acidimetry in non-aqueous environment B. Nitritometry C. Complexonometry D. Alkalimetry in non-aqueous environment E. Alkalimetry in alcohol-chloroform environment 294. What reagent can be used to determine phenol hydroxyl in the morphine hydrochloride molecule? A. Sulfanilic acid (diazonium salt) B. Sodium hydroxide C. Vanillin solution in glycerin D. *Iron (III) chloride E. Hydrogen peroxide 295. Characteristic reaction for ethylmorphine hydrochloride is formation of: A. Taleyoquine B. Murexide C. *Iodoform D. Aurine dye E. Ethylmorphine hydroxamate 296. Apomorphine hydrochloride is used in the medical practice as: A. *Emetic mean B. Narcotic analgesic mean C. Uterine muscular stimulant D. Antitussive mean E. Expectorant mean 297. Assay of codeine according to the SPhU requirements is conducted by the following method: A. Gravimetry B. Permanganatometry C. *Acidimetry in non-aqueous environment D. Nitritometry E. Acidimetry in aqueous environment 298. Choose the sours for glaucine hydrochloride obtaining: A. *Glaucinum flavum B. Rauwolfia C. Passiflora incarnata D. Emetic nut E. Convallaria majalis 299. Determine the molecular mass of the morphine hydrochloride equivalent at its assay by acidimetry in non-aqueous environment: A. 1/4 М m B. 2 М m C. *М m D. 1/2 М m E. 1/5 М m 300. Medical drug atropine sulfate according to its chemical structure belongs to the derivatives of: A. *Tropine B. Purine C. Indole D. Imidazole E. Quinolysine 301. To the alkaloids’ group medical drugs, morphinane derivatives, the following compound belongs: A. Physostigmine salicylate B. *Morphine hydrochloride C. Papaverine hydrochloride D. Apomorphine hydrochloride E. Caffeine monohydrate 302. Codeine phosphate in the medical practice is used as: A. Anesthetic mean B. Expectorant mean C. Uterine muscular stimulant D. Anticholinesterase mean E. *Antitussive mean 303. Determine the molecular mass of the apomorphine hydrochloride equivalent at its assay by acidimetry in non-aqueous environment: A. 1/4 М m B. 2 М m C. *М m D. 1/2 М m E. 1/5 М m 304. To the alkaloids’ group medical drugs, indole derivatives, the following compound belongs: A. Pilocarpine hydrochloride B. *Physostigmine salicylate C. Platyphylline hydrotartrate D. Cocaine hydrochloride E. Papaverine hydrochloride 305. Proserin in the medical practice is used as: A. Anesthetic mean B. Cholinolytic mean C. Adrenomimetic mean D. *Anticholinesterase mean E. Antitussive mean 306. What salt of strychnine is used as medical drug? A. Sulfate B. *Nitrate C. Hydrobromide D. Benzoate E. Phosphate 307. Reserpine can be allocated from the roots of: A. Cytisus laburnum B. Thermopsis lanceolata C. Sophora pachycarpa D. Senecio plathyphyllus E. *Rauwolfia serpentina Benth 308. What reagent can be used to determine salicylate-ion in the physostigmine salicylate molecule? A. Sodium nitroprusside B. Sodium hydroxyde C. Vanillin solution in glycerin D. *Iron (III) chloride E. Sodium carbonate 309. Determine molecular mass of the caffeine at its assay by reverse iodometry method: A. *1/4 М m B. 2 М m C. М m D. 1/2 М m E. 1/5 М m 310. What reagent can be used to determine benzoate-ion in the sodium caffeine-benzoate molecule? A. Sodium nitroprusside B. Sodium hydroxyde C. Vanillin solution in glycerin D. *Iron (III) chloride E. Nitric acid 311. Which of the following preparations has chemical name 1,3,7–trimethylxanthine? A. Codeine B. *Caffeine C. Reserpine D. Theobromine E. Proserin 312. Choose the reaction for theobromine identification: A. Pellagri B. Vitali-Morin C. Taleyoquine test D. *Murexide sample E. Periodide formation 313. Medical drug euphylline according: A. Morphinane B. *Purine C. Indole D. Aporphine E. Quinolysine 314. Physostigmine salicylate in the medical practice is used as: A. Anesthetic mean B. Cholinolytic mean C. Uterine muscular stimulant D. *Anticholinesterase mean E. Antitussive mean 315. To the alkaloids’ group medical drugs, indole derivatives, the following compound belongs: A. *Proserine B. Caffeine C. Ephedrine D. Codeine E. Theobromine 316. Medical drug strychnine nitrate according to its chemical structure belongs to the derivatives of: A. morphinane B. Purine C. *Indole D. Aporphine E. Quinolysine 317. Proserin is used in the medical practice in the form of: A. *Tablets B. Eyes ointments C. Eyes drops D. Ointments E. Tinctures 318. Which of the following preparations has chemical name 1,3–dimethylxanthine monohydrate: A. Codeine B. Caffeine C. Reserpine D. Theobromine E. *Theophylline 319. Pentoxifylline according to its chemical structure belongs to the derivatives of: A. Caffeine B. *Theobromine C. Theophylline D. Physostigmine E. Atropine 320. Medical drug theobromine according to its chemical structure belongs to the derivatives of: A. Morphinane B. *Purine C. Indole D. Aporphine E. Quinine 321. Choose the reaction for theophylline identification: A. Pellagri B. Vitali-Morin C. Taleyoquine sample D. *Murexide sample E. Periodide formation 322. Physostigmine salicylate is used in the medical practice in the form of: A. Powder B. Injection solutions C. *Eyes drops D. Creams E. Vaginal suppositories 323. Medical drug proserin according to its chemical structure belongs to the derivatives of: A. Morphinane B. Purine C. *Indole D. Aporphine E. Quinine 324. To the alkaloids’ group medical drugs, indole derivatives, the following compound belongs: A. Pilocarpine hydrochloride B. *Strychnine nitrate C. Platyphylline hydrotartrate D. Cocaine hydrochloride E. Papaverine hydrochloride 325. Reserpine in the medical practice is used as: A. Anesthetic mean B. Cholinolytic mean C. Uterine muscular stimulant D. *Hypotensive mean E. antitussive mean 326. Which of the following preparations has chemical name 1,3,7–trimethylxanthine: A. Codeine B. *Caffeine C. Reserpine D. Theobromine 327. of: E. Proserin Medical drug euphylline according to its chemical structure belongs to the derivatives A. B. C. D. E. Morphinane *Purine Indole Aporphine Quinine 328. Caffeine in the medical practice is used as: A. Anesthetic mean B. Cholinolytic mean C. *CNS stimulant D. Uterine muscular stimulant E. Antitussive mean 329. Assay of theophylline is conducted according to the AND requirements by the following method: A. Gravimetry B. Complexonometry C. Nitritometry D. Acidimetry in aqueous environment E. *Alaklimetry, titration by the substitute 330. What medical drug has the following structural formula? H C H C CH3 HCl OH NHCH3 A. B. C. D. E. 331. Cytisine *Ephedrine hydrochloride Platyphylline hydrotartrate Pilocarpine hydrochloride Quinine hydrochloride What medical drug has the following structural formula? H3C NH CH H3C C H C H A. B. C. D. E. 332. C2H5 O C H2 C H2 O C H2 C H2 N H C 2 C6H5COOH NH2 Cytisine Sodium caffeine-benzoate Spherophysine salicylate Pilocarpine hydrochloride *Spherophysine benzoate What medical drug has the following structural formula? C H2 A. B. C. D. E. 333. N H N CH3 HCl N Pachicarpine hydroiodide Ephedrine hydrochloride Platyphylline hydrotartrate *Pilocarpine hydrochloride Quinine hydrochloride What medical drug has the following structural formula? CH3 CH3 H3C C H C C H2 O C C H O C OH C O O HO HOOC CH2 H C C H COOH OH N A. B. C. D. E. 334. Platyphylline benzoate Ephedrine hydrochloride *Platyphylline hydrotartrate Pilocarpine hydrochloride Cytisine What medical drug has the following structural formula 5? NH N O A. B. C. D. E. 335. Platyphylline benzoate Ephedrine hydrochloride Platyphylline hydrotartrate Pilocarpine hydrochloride *Cytisine What medical drug has the following structural formula? N CH2 HI N A. B. C. D. E. 336. Pachicarpine hydrochloride Ephedrine hydrochloride Platyphylline hydrotartrate Pilocarpine hydrochloride *Pachicarpine hydroiodide What medical drug has the following structural formula? HC CH2 HO CH H3CO * H2SO4 * 2H2O N A. B. C. D. E. 337. N 2 Pachicarpine sulfate Atropine sulfate Quinine hydrosulfate *Quinine sulfate Quinine hydrochloride What medical drug has the following structural formula? HC CH2 HO CH N H3CO * HCl *2H 2O N A. B. C. D. E. 338. Pachicarpine hydrochloride Ephedrine hydrochloride Quinine dihydrate Quinine sulfate *Quinine hydrochloride What medical drug has the following structural formula? HC CH2 HO CH N H3CO * 2HCl N A. B. C. D. E. 339. Pachicarpine hydrochloride Ephedrine hydrochloride Quinine dihydrate *Quinine dihydrochloride Quinine hydrochloride What medical drug has the following structural formula? CH2OH N CH3 O C CH C6H5 * H2SO4 * H2O O 2 A. B. C. D. E. 340. Quinine sulfate *Atropine sulfate Scopolamine sulfate Cocaine sulfate Tropacine What medical drug has the following structural formula? CH2OH O N CH3 O C CH C6H5 * HBr * 3 H2O O A. B. C. D. E. 341. Homatropine hydrobromide Atropine hydrobromide *Scopolamine hydrobromide Cocaine bromide Tropacine What medical drug has the following structural formula? OH N CH3 O C CH C6H5 * HBr O A. B. C. D. E. 342. *Homatropine hydrobromide Atropine bromide Scopolamine hydrobromide Cocaine bromide Tropacine What medical drug has the following structural formula? C6H5 N CH3 O C CH C6H5 * HCl O A. B. C. D. E. 343. Homatropine hydrochloride Morphine hydrochloride Papaverine hydrochloride Cocaine hydrochloride *Tropacine What medical drug has the following structural formula? COOCH3 N CH3 O C C6H5 * HCl O A. B. C. D. E. 344. Homatropine hydrochloride Morphine hydrochloride Papaverine hydrochloride *Cocaine hydrochloride Tropacine What medical drug has the following structural formula? H3CO N H3CO H3CO CH2 * HCl H3CO A. B. C. D. E. 345. *Papaverine hydrochloride Morphine hydrochloride Drotaverine hydrochloride Cocaine hydrochloride Tropacine What medical drug has the following structural formula? C2H5O NH C2H5O C2H5O CH * HCl C2H5O A. B. C. D. E. 346. Papaverine hydrochloride Morphine hydrochloride *Drotaverine hydrochloride Cocaine hydrochloride Tropacine What medical drug has the following structural formula? HO * HCl * 3 H2O O N CH3 HO A. B. C. D. E. 347. Papaverine hydrochloride *Morphine hydrochloride Drotaverine hydrochloride Cocaine hydrochloride Tropacine What medical drug has the following structural formula? H3CO * H2O O N CH3 HO A. B. C. D. E. 348. Caffeine Morphine *Codeine Cocaine Tropacine What medical drug has the following structural formula? C2H5O O * HCl * 2 H2O N CH3 HO A. Papaverine hydrochloride B. Morphine hydrochloride 349. C. Drotaverine hydrochloride D. Cocaine hydrochloride E. *Ethylmorphine hydrochloride What medical drug has the following structural formula? HO HO * HCl * 3/4 H2O N A. B. C. D. E. 350. CH3 Papaverine hydrochloride Morphine hydrochloride *Apomorphine hydrochloride Cocaine hydrochloride Ethylmorphine hydrochloride What medical drug has the following structural formula? OCH3 H3CO * HCl H3CO N CH3 H3CO A. B. C. D. E. 351. Papaverine hydrochloride Morphine hydrochloride Apomorphine hydrochloride *Glaucine hydrochloride Ethylmorphine hydrochloride What medical drug has the following structural formula? CH3 H 3C N H C O COOH O A. B. C. D. E. 352. * N N CH3 CH3 OH Spherophysine benzoate *Physostigmine salicylate Proserin Resorcinol Caffeine What medical drug has the following structural formula? H3C + N C O N H3C 353. CH3 CH3 O A. B. C. D. E. CH3 CH3SO4 - Spherophysine benzoate Physostigmine salicylate *Proserin Resorcinol Caffeine What medical drug has the following structural formula? N N O O A. B. C. D. E. 354. *Strychnine Physostigmine Reserpine Proserin Theobromine What medical drug has the following structural formula? N H3CO N H OCH3 H3COOC O OCH3 C OCH3 O OCH3 A. B. C. D. E. 355. Strychnine Diprophylline Proserin Theobromine *Reserpine What medical drug has the following structural formula? O H3C N N N O CH3 N CH3 A. Cocaine B. Theophylline C. Theobromine D. *Caffeine E. Codeine What medical drug has the following structural formula? O O 356. C H3C N N CH3 ONa * N O A. B. C. D. E. 357. N CH3 *Sodium caffeine-benzoate Spherophysine benzoate Codeine Pentoxifylline Euphylline What medical drug has the following structural formula? O HN O N N CH3 N CH3 A. Tropacine B. Theophylline C. *Theobromine D. Caffeine E. Codeine 358. What medical drug has the following structural formula? O H3C N NH N O N CH3 A. Tropacine B. *Theophylline C. Theobromine D. Caffeine E. Codeine 359. What medical drug has the following structural formula? O O H 3C C C H2 C H2 C H2 C H2 N O N N CH3 N CH3 A. B. C. D. E. 360. H 3C Proserin Theobromine *Pentoxifylline Diprophylline Euphylline What medical drug has the following structural formula? O N NH H2C NH2 H 2C NH2 * O N 361. CH3 Caffeine Theophylline Diprophylline Pentoxifylline *Euphylline What medical drug has the following structural formula? A. B. C. D. E. N O OH H3C N O N A. B. C. D. E. 362. H3C O N C H2 C H CH2OH N CH3 Caffeine Theophylline *Diprophylline Pentoxifylline Euphylline What medical drug has the following structural formula? O OH N N N N C H2 C H C H2 N COOH CH3 * CH2CH2OH N CH3 A. Diprophylline B. Physostigmine salicylate C. Pentoxifylline D. *Xanthinol nicotinate E. Euphylline 363. Separate accordingly equipped production area for the production (manufacturing) of medicines in the pharmacy - it is: A. A block B. *An assistant room C. A production room D. A production department E. A material room 364. Documentation that a particular method, process, equipment, activity or system of actions lead to the expected and guaranteed result – it is: A. A technological order B. AND C. *A validation D. A contamination E. A calibration 365. Complex of preventive measures and types of control that is carried out right in the drugstore – it is: A. A factory control B. A quality check C. An exclusion of unfit drugs D. A laboratory control E. *A control within a drugstore 366. For the preparation of intravenous infusions, injections, which are not subjected to thermal sterilization, it is necessary to use sterile water: A. Purified B. *For injections C. High purity D. Drinking E. Distilled 367. All types of control within a drugstore should possess: A. Pharmacist analyst, pharmacist B. Head of drugstore, chemist C. *Head of drugstore, his assistants, pharmacist analyst, chemist D. Pharmacist, nurse E. Head of drugstore, his assistants 368. What kind of control is obligatory and is to check the appearance of a medicinal product, including the quality of blockage, its color, smell, homogeneity of mixing, the lack of mechanical insertions in liquid medical products? A. Written B. Chemical C. Questionnaire D. Control at selling E. *Organoleptic 369. Purified water (not for injections) is checked for the absence of admixtures:. A. Chlorides, restoration matter and ammonia B. Radioactivity only if there is an analyst in the staff C. *Chlorides, sulfates, calcium salts D. Heavy metals, arsenic, aluminum E. Ammonia oxidizing agents, magnesium 370. Water, from which injection solutions and medicines for infants are prepared, is checked in the drugstore for: A. *Chlorides, sulfates, calcium and ammonium salts, carbon dioxide of reducing substances B. Nitrates, heavy metals C. Reducing substances, ammonia D. Calcium salts, arsenic E. Heavy metals, sulfates 371. The result of the reaction in the determination of chloride ions in the purified water is: A. Gray sendiment B. *Opalescence C. Yellowing of the solution D. The appearance of pink color E. The appearance of brown color 372. An internal document of management agent, which defines the technological methods, technical means, rules and regulations of medical product manufacturing, methods of control, and establish quantitative and qualitative indicators of medical product, its acceptable bounds, the requirements for packaging, marking, storage conditions, serviceable life is called : A. Technological order B. *Technological direction C. Validation D. Contamination E. Calibration 373. Medicines are given handly application state, which provides them with the desired medicinal effect and it is called: A. B. C. D. E. *Medicinal form Medicinal species Medical product Medical form Factory packaging Contamination of concentrated solutions, intermediates and patent medicines is 374. called: A. Validation B. Constopation C. Rejects D. *Contamination E. Microbiological purity 375. Form of within a drugstore storage without dosage, previously produced in the drugstore mixture of two or more drugs that are combined in proportions, that often occur in prescriptions of medicines is called: A. Concentrates B. Blends C. *Semi finished products D. Fixanales E. Manufactured goods 376. For the preparation of eye drops, which are subjected to further thermal sterilization, it is necessary to use the following type of water: A. Distilled B. *Cleaned in containers C. Drinking D. For injections E. From tap 377. What type of control is not used in the pharmacy: A. Written B. Chemical C. Physics D. *Laboratory E. Questionnaire 378. What control lies in verifying the total weight or volume of a medicinal product, quantity and mass of individual doses, which are included in this dosage form (but not less than three doses)? A. Written B. Chemical C. *hysics D. Laboratory E. Questionnaire 379. Water for injections and eye drops are checked for the absence of admixtures: A. Oxalates, phenols, iron, zinc, cyanides B. *Chlorides, sulfates, calcium salts, reducing substances, ammonia and carbon dioxide C. Reducing substances, ammonia, carbon dioxide and lead salts D. Heavy metals, ammonia, fluoride E. Heavy metals, arsenic, aluminum 380. Head of pharmacy, his deputy, chemist, pharmacist analyst must possess within a drugstore types of control: A. Individual B. Questionnaire C. All species except chemical D. Just admission E. *All types 381. In determining the calcium ions in purified water test solution is compared with: A. Distilled water B. *Standard solution C. Purified water D. Alcohol E. Another calcium solution 382. Sodium salt, wetted with chloride acid and put into a colorless flame, stains it in the following color: A. Red B. Green C. *Yellow D. Violet E. Brick red 383. To identify potassium ions in extemporal medical forms chemist analyst may use the following reagents: A. Ammonium oxalate B. *Sodium hexonitrocobalt (III) in presence of CH3COOH C. Sodium hexohydroxostibatin D. Silver nitrate in the nitrate acid medium E. Potassium dichromate in the sulphate acid medium 384. Medical product that contains hexamethylenetetramine and sodium salicylate was received for analysis. What reagent when heated can detect simultaneously these two preparations? A. Sodium hydroxide B. Concentrated chloride acid C. *Sulphate acid concentrated D. Sulphate acid diluted E. Sodium nitrite 385. Pharmacist analyst analyzes the quality control of medical form, which contains boric acid. Identification of the latter is carried out with the help of boromethylic esther formation, which burns with the flame that has edging of the following colour: A. Yellow B. *Green C. Blue D. Red E. Brown 386. To identify analgin in extemporal medical forms the following reagents may be used: A. *Chloride acid diluted, chloramine solution B. Sodium hydroxide, chloramine solution C. Nitrate acid, silver nitrate D. Hydrogen peroxide solution, ammonia solution E. Chloride acid diluted, sodium nitrite 387. To identify streptocid in medical form one adds chloride acid, sodium nitrite solution, β-naphthol solution. During this process azo dye appears and it is colored: A. Yellow B. Blue C. Green D. *Cherry red E. Black 388. For rapid qualitative analysis of novocaine in medical forms the following reaction is used: A. Murexide test B. *Lignine test C. Legal D. Pellagry E. Diazotization 389. Sodium benzoate and sodium salicylate are defined in rapid analysis simultaneously with the help of the following solution: A. *Iron (III) chloride B. Sodium nitrite C. Cobalt (II) nitrate D. Sulphate acid E. Silver nitrate 390. To identify bromide ions in medical form analyst used solution of silver nitrate. He will observe the formation of the following sediment: A. White, which is light soluble in ammonia B. White, which is insoluble in ammonia C. Light yellow, which is easily soluble in ammonia solution D. *Light yellow, which is soluble in concentrated ammonia solution E. Yellow, which is soluble in ammonia 391. To identify chloride ions in extemporal medical forms chemist analyst may use the following reagents: A. Ammonium oxalate B. Sodium cobaltnitrite in the presence of CH3COOH C. *Silver nitrate in the nitrate acid medium D. Potassium hexahydroxystibatin after previously added potassium carbonate and boiling and then cooling E. Potassium dichromate in sulphate acid medium 392. The following medical form was sent to analysis: ascorbic acid 0.1 and glucose 0.5. On what chemical properties of both drugs is based the qualitative rapid analysis of this medical preparation? A. Acid B. Main C. Oxidative D. *Restoration E. Amphoteric 393. Acetylsalicylic acid in the extemporal drugs is determined by the following reagent: A. *Marky B. Legal C. Dragendorf D. Raymond E. Erdman 394. To identify calcium ions in extemporal medical forms chemist analyst may use the following reagents: A. *Ammonium oxalate in the presence of CH3COOH B. Sodium cobaltinitrite in the presence of CH3COOH C. Silver nitrate in the nitrate acid medium D. Potassium hexahydroxystibatin after previously added potassium carbonate and boiling and then cooling E. Potassium dichromate in sulphate acid medium 395. To identify ammonium ions extemporal medical form is heated with a solution of sodium hydroxide. In this case, there is the smell of: A. B. C. D. E. Phenol Amine *Ammonia Sulphur oxide Nitric oxide (IV) 396. Novocaine and resorcin in medical preparations can be identified simultaneously by using the following reagents: A. Diluted chloride acid, solution of chloramine B. Sodium hydroxide, chloramine solution C. Nitrate acid, silver nitrate D. Hydrogen of peroxide solution, ammonia solution E. *Diluted chloride acid, sodium nitrite and sodium hydroxide solutions 397. Medical form which contains hexamethylenetetramine and sodium salicylate was sent to analysis. At heating it with sulphate acid there appears: A. White sediment B. *Raspberry-red color C. Yellow color D. Yellow sediment E. Green color 398. For qualitative rapid analysis of aminophylline in drugs the following reaction is used: A. *Murexide sample B. Lignine sample C. Legal D. Pellagry E. Diazotization 399. Medical form which contains hexamethylenetetramine and streptocid was sent to analysis. What reagent at the process of heating can simultaneously detect the two drugs? A. Sodium hydroxide B. Concentrated chloride acid C. Sulfate acid concentrated D. *Sulphate acid diluted E. Sodium nitrite 400. Chloride acid in extemporal medical forms is identified by the following solution: A. Phenolphthalein B. Starch C. *Methyl red D. Thymolphthalein E. Bromphenol blue 401. Sodium benzoate and sodium salicylate are simultaneously defined in rapid analysis with the following solution: A. *Iron (III) chloride B. Sodium nitrite C. Cobalt (II) nitrate D. Sulphate acid E. Silver nitrate 402. One of the reactions to identify potassium ions is the reaction with sodium cobaltnitrit. Analytical effect in this case is: A. Gassing B. The formation of white sediment which is soluble in ammonia C. The formation of white sediment, which is insoluble in acetate acid D. *The formation of yellow or orange-yellow sediment, which is insoluble in acetate acid E. Opalescence 403. Select a reagent which is used to identify any of the anions (chloride, bromide, iodide) in their common presence in drugs: A. Iron (II) sulfate B. Sodium nitrite C. Cobalt (II) nitrate D. Sulphate acid E. *Silver nitrate 404. The following medical form was sent to analysis: ascorbic acid 0.1 and glucose 0.5. Silver nitrate is added to the powder solution to reveal ascorbic acid. In this case, the following analytical effect is observed: A. White sediment B. Pink color C. *Gray sediment D. Gassing E. Blue color 405. Acetylsalicylic acid in extemporal drugs is determined by the solution of: A. *Iron (III) chloride B. Sodium nitrite C. Cobalt (II) nitrate D. Sulphate acid E. Silver nitrate 406. Medical form of the following composition was sent to analysis: sodium chloride 0.2; sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. Quantitative determination of sodium chloride is carried out by: A. Argentometry of Folgard B. Alkalimetry C. Argentometry of Mor D. Acidimetry E. *Argentometry of Fajans 407. Medical form of the following composition was sent to analysis: sodium chloride 0.2; sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. The amount of sodium hydrocarbonate and sodium tetraborate is quantitated by: A. Argentometry of Folgard B. Alkalimetry C. Argentometry of Mor D. *Acidimetry E. Argentometry of Fajans 408. Medical form of the following composition was sent to analysis: sodium chloride 0.2; sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. The content of sodium tetraborate after convertion into boric acid is quantitatively determined by the method of: A. Argentometry of Folgard B. *Alkalimetry C. Argentometry of Mor D. Acidimetry E. Argentometry of Fajans 409. Medical form of the following composition was sent to analysis: sodium chloride 0.2; sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. Quantitative determination of sodium chloride by titration of 1 ml of the medical preparation by standard 0.1 M of the following solution: A. Chloride acid B. C. D. E. Sodium hydroxide *Silver nitrate Sodium edetate Sodium thiosulfate 410. Medical form of the following composition was sent to analysis: sodium chloride 0.2; sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. Amount of sodium bicarbonate and sodium tetraborate quantitated by titrating 1 ml of the medical preparation by standard 0.1 M of the following solution: A. *Chloride acid B. Sodium hydroxide C. Silver nitrate D. Sodium edetate E. Sodium thiosulfate 411. Medical form of the following composition was sent to analysis: sodium chloride 0.2; sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. The content of sodium tetraborate after converted into boric acid was quantitatively determined by titrating 1 ml of the medical preparation by standard 0.1 M of the following solution: A. Chloride acid B. *Sodium hydroxide C. Silver nitrate D. Sodium edetate E. Sodium thiosulfate 412. Medical form of the following composition was sent to analysis: sodium chloride 0.2; sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. Quantitative determination of sodium chloride is conducted by argentometry using as an indicator the solution of: A. Phenolphthalein B. Methyl orange C. Potassium chromate D. Iron ammonium sulfate E. *Bromophenol blue 413. Medical form of the following composition was sent to analysis: sodium chloride 0.2; sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. The amount of sodium hedrocarbonate and sodium tetraborate quantitavely is determined by acidimetry using as an indicator the solution of: A. Phenolphthalein B. *Methyl orange C. Potassium chromate D. Iron ammonium sulfate E. Bromophenol blue 414. Medical form of the following composition was sent to analysis: sodium chloride 0.2; sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. The content of sodium tetraborate is determined by alkalimetry after convertion into boric acid using as an indicator the solution of: A. *Phenolphthalein B. Methyl orange C. Potassium chromate D. Iron ammonium sulfate E. Bromophenol blue 415. Medical form of the following composition was sent to analysis: sodium chloride 0.2; sodium hydrocarbonate 0,4; sodium tetraborate 0,4; purified water up to 40.0 ml. The content of sodium tetraborate is determined by alkalimetry after convertion into boric acid by adding neutralizing to phenolphthalein: A. Formaldehyde B. *Glycerin C. Chloroform D. Ethanol E. Ether 416. Medical form of the following composition was sent to analysis: solution of zinc sulphate 0,25% - 10,0 ml; boric acid 0,2. The quantitative determination of zinc sulfate is carried out by: A. Argentometry B. Alkalimetry C. Iodometry D. Acidimetry E. *Complexometry 417. Medical form of the following composition was sent to analysis: solution of zinc sulphate 0,25% - 10,0 ml; boric acid 0,2. The quantitative determination of boric acid is carried out by: A. Argentometry B. *Alkalimetry C. Iodometry D. Acidimetry E. Complexometry 418. Medical form of the following composition was sent to analysis: solution of zinc sulphate 0,25% - 10,0 ml; boric acid 0,2. The quantitative determination of zinc sulphate is carried out by titrating 1 ml of the medical preparation by standard 0.01 M of the following solution: A. Chloride acid B. Sodium hydroxide C. Silver nitrate D. *Sodium edetate E. Sodium thiosulfate 419. Medical form of the following composition was sent to analysis: solution of zinc sulphate 0,25% - 10,0 ml; boric acid 0,2. The quantitative determination of boric acid is carried out by titrating 0,5 ml of the medical preparation by standard 0.01 M of the following solution: A. Chloride acid B. *Sodium hydroxide C. Silver nitrate D. Sodium edetate E. Sodium thiosulfate 420. Medical form of the following composition was sent to analysis: solution of zinc sulphate 0,25% - 10,0 ml; boric acid 0,2. The quantitative determination of zinc sulfate is carried out by complexometry in the following medium: A. Chloride acid B. Sodium hydroxide C. Buffer solution of pH 3,5 D. Phosphate buffer solution E. *Ammonia buffer solution 421. Medical form of the following composition was sent to analysis: solution of zinc sulphate 0,25% - 10,0 ml; boric acid 0,2. In the quantitative determination of zinc sulfate to indicate the equivalence point the following mixture is used: A. *Acid dark blue B. C. D. E. Tropeolin 00 and methylene blue Methyl orange and methylene blue Methyl red and methylene blue Bromophenol blue and bromthymol blue 422. Medical form of the following composition was sent to analysis: solution of zinc sulphate 0,25% - 10,0 ml; boric acid 0,2. For the quantitative determination of boric acid at first deposition of zinc sulfate is carried out by the solution of: A. Silver nitrate B. *Potassium ferrocyanide (II) C. Potassium ferrocyanide (III) D. Barium chloride E. Ammonium oxalate 423. Medical form of the following composition was sent to analysis: solution of zinc sulphate 0,25% - 10,0 ml; boric acid 0,2. The content of boric acid is determined by alkalimetry by adding neutralizing to phenolphthalein: A. Formaldehyde B. *Glycerine C. Chloroform D. Ethanol E. Ether 424. Medical form of the following composition was sent to analysis: solution of zinc sulphate 0,25% - 10,0 ml; boric acid 0,2. What is the molar mass of zinc sulfate equivalent in the quantitative determination of it by the method of complexometry? A. 1/4 М. m. B. 2 М. m. C. *М. m. D. 1/2 М. m. E. 1/5 М. m. 425. Medical form of the following composition was sent to analysis: solution of zinc sulphate 0,25% - 10,0 ml; boric acid 0,2. What is the molar mass of boric acid equivalent in the quantitative determination of it by the method of alkalimetry? A. 1/4 М. m. B. 2 М. m. C. *М. m. D. 1/2 М. m. E. 1/5 М. m. 426. Pharmacist analyst analyzes the following medical product composition: ascorbic acid 0.1, glucose 0.5. At the same time ascorbic acid is quantified by the method of: A. A Argentometry of Mor B. Alkalimetry, reverse titration C. *Iodometry, direct titration D. Acidimetry, direct titration E. Complexometry 427. Pharmacist analyst analyzes following medical product composition: ascorbic acid 0.1, glucose 0.5. At the same time glucose is quantified by the method of: A. Argentometry of Mor B. Alkalimetry, reverse titration C. *Iodometry, direct titration D. Acidimetry, direct titration E. Complexometry 428. Pharmacist analyst analyzes following medical product composition: ascorbic acid 0.1, glucose 0.5. At the same time glucose is quantified by the iodometry method using as an indicator the solution of: A. Methyl orange B. *Starch C. Phenolphthalein D. Bromophenol blue E. Tropeolin 00 429. Pharmacist analyst analyzes following medical product composition: ascorbic acid 0.1, glucose 0.5. At the same time both components are quantified in a single sample of powder by the method of: A. Argentometry B. Alkalimetry C. *Iodometry D. Acidimetry E. Complexometry 430. Pharmacist analyst analyzes following medical product composition: ascorbic acid 0.1, glucose 0.5. Quantitative determination of both components in a single batch of powder based on the following their chemical properties: A. Main B. Acid C. Oxidative D. *Restoration E. Amphoteric 431. Pharmacist analyst analyzes following medical product composition: ascorbic acid 0.1, glucose 0.5.What is the molar mass of ascorbic acid equivalent in the quantitative determination of it by the method of iodometry, direct titration? A. 1/4 М. m. B. 2 М. m C. М. m. D. *1/2 М. m. E. 1/5 М. m. 432. Pharmacist analyst analyzes following medical product composition: ascorbic acid 0.1, glucose 0.5.What is the molar mass of glucose equivalent in the quantitative determination of it by the method of iodometry, direct titration? A. 1/4 М. m. B. 2 М. m. C. М. m. D. *1/2 М. m. E. 1/5 М. m. 433. Pharmacist analyst analyzes following medical product composition: ascorbic acid 0.1, glucose 0.5. In the quantitative determination of ascorbic acid by the iodometry method titration is carried out until the non-vanishing staining of the following colour appears: A. *Yellow B. Blue C. Red D. Violet E. Green 434. What kind of admixture in the purified water “in bulk” is determined by the reaction chemistry of which is depicted in picture? [O] N H 2 N H H2SO4êî í ö. N H [O] N N H H2SO4êî í ö. - + HSO4 A. B. C. D. E. Heavy metals *Nitrates Substances that are oxidized Aluminum Electric conductivity 435. What reagent reveals nitrate admixtures in the purified water in containers on the reaction chemistry of which is depicted in picture? [O] N H 2 N H H2SO4êî í ö. N H [O] N N H H2SO4êî í ö. - + HSO4 A. B. C. D. E. Aniline Ethylenediamine Phenylamine Dibenzylamine *Diphenylamine 436. What is the analytical effect of the reaction of nitrate admixture identification in water for injections “in bulk” the chemistry of which is represented in picture? [O] N H 2 N H H2SO4êî í ö. N H [O] N N H H2SO4êî í ö. - + HSO4 A. B. C. D. E. Green coloration Red sediment *Blue coloration Red coloration White sediment 437. What kind of admixture in the purified water “in bulk” is determined by the reaction chemistry of which of is depicted in picture? SH S H3C H3C C NH NH2 H3C C NH A. *Heavy metals B. Nitrates C. Substances that are oxidized S S SH Me2+ + 2 H3C ; C Me C N H C N H CH3 + 2H+. D. Aluminum E. Electric conductivity 438. What reagent reveals the heavy metals admixture in the purified water in containers on the reaction the chemistry of which is depicted in picture? SH S H3C H3C C NH NH2 H3C C S S SH Me2+ + 2 H3C ; C Me C C N H NH CH3 + 2H+. N H A. B. C. D. E. 8-oxine Thiourea Thioglycolic acid Diphenylamine *Tioacetamide 439. What is the analytical effect of the heavy metals admixture detection reaction in water for injections “in bulk” the chemistry of which is described in picture? SH S H3C H3C C NH NH2 H3C C NH S S SH Me2+ + 2 H3C ; C Me C N H C CH3 + 2H+. N H A. B. C. D. E. Green coloration Red sediment *Brown coloration Blue coloration White sediment 440. What reagent reveals the ammonium salts admixture in the purified water in containers on the reaction the chemistry of which is depicted in picture? NH4+ + 2[HgI4]2- + 2OH- [NH2Hg2I2] I + 5I- + 2H2O A. B. C. D. E. Dragendorf Tollens Diphenylamine Tioacetamide *Nesler 441. What is the analytical effect of the ammonium salts admixture detection reaction in the purified water in containers the chemistry of which is represented in picture? NH4+ + 2[HgI4]2- + 2OHA. B. C. D. E. [NH2Hg2I2] I + 5I- + 2H2O Green coloration Red sediment *Yellow coloration Brown coloration White sediment 442. What is the analytical effect of the chlorides admixture detection reaction in the purified water in containers the chemistry of which is described in picture? Cl- + Ag+ HNO3 AgCl A. B. C. D. E. White coloration Red sediment *Opalescence Yellow sediment White sediment 443. What is the analytical effect of the sulphate admixture detection reaction in the purified water in containers the chemistry of which is depicted in picture? HCl SO42- + Ba2+ BaSO4 A. B. C. D. E. White coloration Red sediment *Opalescence Yellow sediment White sediment 444. What is the analytical effect of the reaction with the help of which pharmacist analyst conducts qualitative rapid analysis of the thiamine hydrochloride solution, and the chemistry of which is represented in picture? CH3 CH3 H2C N + - N O C HS S H3C N + N Cl *HCl + NaOH N H2C CH2CH2OH N H3C NH2 H CH2CH2OH NH2 CH3 N + N K3[Fe(CN)6] N H3C N S CH2CH2OH . A. B. C. D. E. Red coloration *Blue fluorescence Blue coloration White sediment Yellow fluorescence 445. What is the reaction by which pharmacist analyst conducts qualitative rapid analysis of the thiamine hydrochloride solution, and the chemistry of which is described in picture? CH3 CH3 H2C N + - N CH2CH2OH H3C NH2 CH3 N + O C HS S H3C N + N Cl *HCl + NaOH N H2C N K3[Fe(CN)6] H3C N A. Tallium test B. *Thiochrome test C. Hydroxamic reaction N S CH2CH2OH . N H NH2 CH2CH2OH D. The reaction of Vitaly-Moren E. Maltase test 446. The test mixture sample, which contains 0,005-0,01 g of purine alkaloid was placed into the porcelain cup, added 3 drops of HCl diluted, 5 drops of perhydrol and evaporated to dryness on water bath . A drop of NH4OH was added to the residue. What is the combination that is formed as a result of this reaction and is depicted in picture? O O H3C CH3 N O N N O H4NO CH3 N O N CH3 A. B. C. D. E. Tallium Diphenylcarbinol 1,3-Dimethylalloxan Methylalloxan *Murexide 447. 1 ml of NaOH solution and 1 ml of 0.5% solution of alpha-naphthol in 40% ethanol was added to 5 ml of 0.5% streptomycin sulfate solution. The mixture was cooled up to 15 º C and there was added 3 drops of 5% sodium hypobromide solution. What is the color of the compound, which was formed as a result of this reaction and is depicted in picture? O OH NH A. B. C. D. E. Green Red *Violet Blue White 448. What is the analytical effect of the reaction with the help of which pharmacist analyst conducts qualitative rapid analysis of the streptomycin sulfate solution, and the chemistry of which is represented in picture? O O CHO 0 NaOH, t C CH3 OH OH OH A. B. C. D. E. 3+ Fe /3 O O OH FeCl3 CH3 HCl O + HCl . CH3 O Red coloration *Violet coloration Blue fluorescence White sediment Yellow fluorescence 449. What is the reaction by which pharmacist analyst conducts qualitative rapid analysis of the streptomycin sulfate solution, and the chemistry of which is described in picture? A. B. C. D. E. Tallium test *Maltase test Thiochrome test The reaction of Sakaguchy The reaction of Vitaly-Moren 450. Pharmacist analyst conducts qualitative rapid analysis of the powder. For this purpose he dissolves the investigated material in 0.1 M of sodium hydroxide solution and adds 2 drops of cobalt nitrate solution. Complex salt of cobalt with the following structure is formed: O C6H5 O C6H5 C6H5 Co C6H5 N O N H N O N H O O What is the analytical effect of this reaction? A. Red coloration B. Blue fluorescence C. Blue coloration D. White and pink sediment E. *Violet sediment 451. What is the analytical effect of the reaction with the help of which pharmacist analyst conducts qualitative rapid analysis of the formaldehyde solution, and the chemistry of which is represented in picture? HO H + H C H + H OH O HOOC H2SO4 COOH H HO C [O] OH H HOOC HO HOOC COOH C H O . COOH A. B. C. D. E. Blue coloration *Red coloration Blue fluorescence White sediment Yellow fluorescence 452. What reagent is used for qualitative rapid analysis of formaldehyde solution on the reaction chemistry of which is depicted in picture? CH2O + K2[HgI4] + 3KOH A. B. C. D. E. Dragendorf Tollens Lugol Felling *Nessler Hg + HCOOK + 4KI + 2H2O 453. Pharmacist analyst conducts qualitative rapid analysis of the drug. He adds a drop of concentrated HNO3 to 0,001 grams of the investigated powder and heats it. Colored compound of the following structure is formed: H3CO N H3CO O 2N CH2 NO2 H3CO OCH3 Which drug was received for analysis? A. Aminazine B. Phenylephrine hydrochloride C. Morphine hydrochloride D. Riboflavin E. *Papaverine hydrochloride 454. Pharmacist analyst conducts qualitative rapid analysis of the drug. He adds a drop of concentrated HNO3 to 0,001 grams of the investigated powder and heats it. What is the color of the compound of the following structure which was formed as the result of the described reaction? H3CO N H3CO O 2N CH2 NO2 H3CO OCH3 A. B. C. D. E. Red Violet Blue Red *Orange 455. What is the analytical effect of the reaction with the help of which pharmacist analyst conducts qualitative rapid analysis of the adrenaline hydrochloride solution, and the chemistry of which is represented in picture? HO O ClFe OH HO C H CH2 + FeCl3 NHCH3 A. B. C. D. E. Red coloration *Emerald green coloration Blue fluorescence White and pink sediment Yellow orange sediment O OH C H CH2 + 2HCl NHCH3 456. What is the analytical effect of the reaction with the help of which pharmacist analyst conducts qualitative rapid analysis of the adrenaline hydrochloride solution, and the chemistry of which is represented in picture? O HO O OH I2 HO C H CH2 pH 3,56 CH OH NHCH3 N CH2 H3C A. B. C. D. E. Emerald green coloration *Dark red coloration Blue fluorescence White and pink sediment Yellow orange sediment 457. Pharmacist analyst conducts qualitative rapid analysis of the drug. For this purpose he heats 0,1 g of the investigated powder in the test tube of 2 ml filled with diluted chloride acid. The chemistry of this reaction is depicted in picture: H3C H3C N NaO3S CH3 O N HCl CH2 N CH3 H CH3 N N O C6H5 CH3 N C6H5 SO2+CH2O+NaCl What medicine was received for analysis? A. Benzylpenicillin sodium salt B. Sodium caffeine-benzoate C. *Metamizol sodium salt D. Diclofenac sodium E. Vicasol 458. Pharmacist analyst conducts qualitative rapid analysis of the drug. For this purpose he adds 1-2 drops of concentrated H2SO4 to 0,001 grams of the investigated powder. Colored compound of the following structure is formed: CH H H O+ CH2 CH2 N+ CH3 2- SO4 CH3 2 What drug was received for analysis? A. Aminazine B. Mesaton C. Analgin D. Levomycetin E. *Dimedrol 459. Pharmacist analyst conducts qualitative rapid analysis of the drug. For this purpose he adds 1-2 drops of concentrated H2SO4 to 0,001 grams of the investigated powder. What is the color of the compound of the following structure which was formed as the result of the described reaction? CH H H O+ CH2 CH2 N+ CH3 2- SO4 CH3 2 A. B. C. D. E. Red Violet Blue Pink *Orange