HEALTH AND SOCIAL 2010 <89> Database EMBASE Accession Number 2010259348 Authors Van Hout M.C. Institution (Van Hout) School of Health Sciences, Waterford Institute of Technology, Ireland. Country of Publication United Kingdom Title Travellers and substance use - Implications for service provision. Source International Journal of Health Promotion and Education. 48(2)(pp 36-41), 2010. Date of Publication: 2010. Publisher University Dental Hospital Abstract Introduction: The Traveller community as ethnic minority experience many risk factors for problematic substance use relating to their life circumstances, which include; "peer pressure, stress, anxiousness, family crisis, community or neighbourhood dhorganisation, sibling use, parental use, sensation seeking behaviours and depression" (Fountain, 2006). The extent of Traveller drug use remains unknown due to the lack of ethnic identifiers in reporting systems and a lack of Travellers accessing services (Paveepoint, 2005c). Research Aim: The research aimed to yield an anecdotal presentation of Traveller substance use from the perspectives of drug, social, law and community service providers in Ireland. Methods: The research was qualitative in design and consisted of semi structured interviews with service providers (n = 45) in order to generate a more comprehensive picture of current dominant perceptions of the "experiences and issues relating to drug and alcohol use among Travellers". Results: The research findings indicated that drug and alcohol use in the Traveller community in Ireland is increasing in terms of excessive alcohol use, certain drugs used and patterns of problematic substance use. Travellers have poor awareness of potential risks relating to substance use and most are using drugs and alcohol in order to deal with boredom, depression and poverty. Travellers were reported to be difficult to engage with in terms of addiction treatment, due to issues with group work, literacy and family crisis. Conclusion: It is vital to consider the needs of the Travellers and their reported substance use in the development of proactive, culturally specific and supportive drug prevention and treatment protocols. ISSN 1463-5240 Publication Type Journal: Article Journal Name International Journal of Health Promotion and Education Volume 48 Issue Part 2 Page 36-41 Year of Publication 2010 Date of Publication 2010 HEALTH AND SOCIAL 2010 <119> Database EMBASE Accession Number 0020159069 Authors Coghlan M. Macdonald S. Institution (Coghlan) Centre for Addictions Research of British Columbia, University of Victoria, PO Box 1700, Stn CSC, Victoria, Canada V8W 2Y2. Country of Publication United Kingdom Title The role of substance use and psychosocial characteristics in explaining unintentional injuries. Source Accident; analysis and prevention. 42(2)(pp 476-479), 2010. Date of Publication: Mar 2010. Abstract The objective of this study was to examine the relationship between the use of various substances and selected psychosocial characteristics with unintentional injury. Crosssectional data was collected from groups of subjects in treatment for a primary problem with cocaine (n=300), cannabis (n=128), alcohol (n=110), other drugs (n=35), tobacco (n=249), or gambling (n=199). Subjects completed a self-administered questionnaire that included questions on various psychosocial scales (i.e., risk-taking/impulsivity, chronic stress, coping, and social supports), frequency of drug and alcohol use, and unintentional injuries in the year prior to treatment. For the univariate analyses, both frequency of cocaine and cannabis use, risk-taking/impulsivity, stress, and coping were significantly related to injuries. For the multivariate analyses, only risk-taking/impulsivity, stress, age, and sex were significantly related to injuries. The results provide important information regarding factors associated with reported injuries among individuals in addiction treatment. Copyright 2009 Elsevier Ltd. All rights reserved. Publication Type Journal: Article Journal Name Accident; analysis and prevention Volume 42 Issue Part 2 Page 476-479 Year of Publication 2010 Date of Publication Mar 2010 HEALTH AND SOCIAL 2010 <120> Database EMBASE Accession Number 0020159066 Authors Watling C.N. Palk G.R. Freeman J.E. Davey J.D. Institution (Watling) Centre for Accident Research and Road Safety - Queensland, Queensland University of Technology, K Block, 130 Victoria Park Road, Kelvin Grove, QLD, 4059, Australia. Country of Publication United Kingdom Title Applying Stafford and Warr's reconceptualization of deterrence theory to drug driving: can it predict those likely to offend? Source Accident; analysis and prevention. 42(2)(pp 452-458), 2010. Date of Publication: Mar 2010. Abstract In December 2007, random roadside drug testing commenced in Queensland, Australia. Subsequently, the aim of this study was to explore the preliminary impact of Queensland's drug driving legislation and enforcement techniques by applying Stafford and Warr's [Stafford, M.C., Warr, M., 1993. A reconceptualization of general and specific deterrence. Journal of Research in Crime and Delinquency, 30, 123-135] reconceptualization of deterrence theory. Completing a comprehensive drug driving questionnaire were 899 members of the public, university students, and individuals referred to a drug diversion program. Of note was that approximately a fifth of participants reported drug driving in the past six months. Additionally, the analysis indicated that punishment avoidance and vicarious punishment avoidance were predictors of the propensity to drug drive in the future. In contrast, there were indications that knowing of others apprehended for drug driving was not a sufficient deterrent. Sustained testing and publicity of the legislation and countermeasure appears needed to increase the deterrent impact for drug driving. Copyright 2009 Elsevier Ltd. All rights reserved. Publication Type Journal: Article Journal Name Accident; analysis and prevention Volume 42 Issue Part 2 Page 452-458 Year of Publication2010 Date of Publication Mar 2010 PAIN ISSUES <529> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20465361 Status In-Process Authors Candiotti KA. Gitlin MC. Authors Full Name Candiotti, Keith A. Gitlin, Melvin C. Institution Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, FL 33101-6370, USA. kcandiotti@miami.edu Title Review of the effect of opioid-related side effects on the undertreatment of moderate to severe chronic non-cancer pain: tapentadol, a step toward a solution? Source Current Medical Research & Opinion. 26(7):1677-84, 2010 Jul. Journal Name Current Medical Research & Opinion Country of Publication England Abstract OBJECTIVE: Opioids are among the most effective and potent analgesics currently available. Their utility in the management of pain associated with cancer, acute injury, or surgery is well recognized. However, extending the application of opioids to the management of chronic non-cancer pain has met with considerable resistance. This resistance is due in part to concerns related to gastrointestinal and central nervous system-related adverse events as well as issues pertaining to regulatory affairs, the development of tolerance, incorrect drug usage, and addiction. This review focuses on the incidence of opioid-related side effects and the patient and physician barriers to opioid therapy for chronic non-cancer pain. Tapentadol, a centrally acting analgesic with two mechanisms of action, micro-opioid agonism and norepinephrine reuptake inhibition, may be considered to be a partial solution to some of these issues. METHODS: MEDLINE was searched for English-language articles from 1950 to February 2010 using the terms chronic non-cancer pain and opioids together and in combination with undertreatment, adherence, and compliance. RESULTS: The majority of patients treated with traditional opioids experience gastrointestinal- or central nervous system-related adverse events, most commonly constipation, nausea, and somnolence. These side effects often lead to discontinuation of opioid therapy. Concerns about side effects, analgesic tolerance, dependence, and addiction limit the use of opioids for the management of chronic pain. Treatment with tapentadol appears to provide several advantages of an analgesic with a more favorable side-effect profile than the classic microopioid receptor agonist oxycodone (especially related to gastrointestinal tolerability). CONCLUSIONS: The pervasiveness of opioid-associated side effects and concerns related to tolerance, dependence, and addiction present potential barriers to the approval and use of opioids for the management of chronic non-cancer pain. The lower incidence of opioidassociated adverse events and possibly fewer withdrawal symptoms, combined with a satisfactory analgesic profile associated with tapentadol, suggest its potential utility for the management of chronic non-cancer pain. This review will focus on the incidence of opioidrelated side effects and barriers to opioid therapy that are available as English-language articles in the MEDLINE index, and as such, it is a representative but not an exhaustive review of the current literature. Publication Type Journal Article. Research Support, Non-U.S. Gov't. Date of Publication 2010 Jul Year of Publication 2010 Issue/Part 7 Volume 26 Page 1677-84 PAIN ISSUES <530> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20429822 Status In-Process Authors Duensing L. Eksterowicz N. Macario A. Brown M. Stern L. Ogbonnaya A. Authors Full Name Duensing, L. Eksterowicz, N. Macario, A. Brown, M. Stern, L. Ogbonnaya, A. Institution American Academy of Pain Management, Sonora, CA, USA. Title Patient and physician perceptions of treatment of moderate-to-severe chronic pain with oral opioids. Source Current Medical Research & Opinion. 26(7):1579-85, 2010 Jul. Journal Name Current Medical Research & Opinion Country of Publication England Abstract OBJECTIVE: To study physician and patient perceptions of moderate-to-severe chronic pain and its management with oral opioids. METHODS: Two separate surveys were developed and administered to one of two respective study groups: patients and physicians. All study participants recruited from a pool of individuals who had previously agreed to participate in market research. Survey questions addressed the impact of various factors (e.g., quality of life indicators, potential for opioid addiction, side-effects) on pain management decision making, patient satisfaction and compliance. Responses for the first 500 patients and 275 physicians to respond were assessed using descriptive statistics. RESULTS: On average, patients were 53 years of age, white (89%), and female (71%). The majority of patients (80%) had been taking oral opioids longer than 6 months. Physicians reported that 45% of their patients received schedule II opioids, with 27% having severe chronic pain. Patients indicated the most common activities interfered with by chronic pain were exercising (76% of patients), working outside the home (67%), and job responsibilities (60%). When developing a treatment approach physicians considered patients' sleeping (91%), walking (86%), maintaining an independent lifestyle (84%), and job responsibilities (83%). Patients and physicians both rated the ability to relieve pain and the duration of relief as the most important factors when considering opioid therapy. The majority (63%) of patients reported experiencing opioid side effects. When physicians discontinued opioids due to side effects, the most frequent reason was nausea (78%) for immediate-release opioids, and constipation (64%) for extended-release formulations. CONCLUSION: The ability to relieve pain and the duration of that pain relief are the most important factors for both patients and physicians when selecting an opioid. A high percentage of patients surveyed experienced side effects related to their treatment, which may impact adherence and overall treatment effectiveness. Study results should be assessed within study limitations including responder and selection biases, physicians responded about their patients, who were not the same patients surveyed, and the fact that the survey instruments were not formally validated. Further research is warranted to address these limitations. Publication Type Journal Article. Research Support, Non-U.S. Gov't. Date of Publication 2010 Jul Year of Publication 2010 Issue/Part 7 Volume 26 Page 1579-85 HEALTH AND SOCIAL <534> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20528657 Status In-Process Authors Uchtenhagen AA. Authors Full Name Uchtenhagen, Ambros A. Institution Research Institute for Public Health and Addiction, WHO Collaborating Centre for Substance Abuse, Zurich University, Switzerland. uchtenhagen@isgf.uzh.ch <uchtenhagen@isgf.uzh.ch> Title Ethical perspectives in caring for people living with addictions: The European experience. Source International Review of Psychiatry. 22(3):274-80, 2010. Journal Name International Review of Psychiatry Country of Publication England Abstract European policy and practice in caring for people living with addictions is based on defined values (human rights, medical ethics) and on research evidence for the effects and impact of interventions. The focus of the paper is on risk management approaches to reduce the negative consequences of continued illicit drug use, being the ethically most debatable issue. The legal and policy positions are set by the European Council and Commission, and their translation into practice is documented centrally in the European Monitoring Centre on Drugs and Drug Addiction, showing the general trends as well as national differences. The European experience with the risk management approaches is presented in terms of research evidence on their effects and side-effects; this evidence is justifying the present practice. The perspectives for the future are set to follow the same lines, in a continued effort to find a balance of interests, in cooperation of authorities and civil society, and guided by ongoing research. Publication Type Journal Article. Date of Publication 2010 Year of Publication 2010 Issue/Part 3 Volume 22 Page 274-80 HEALTH AND SOCIAL <537> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20056521 Status In-Process Authors Benton D. Authors Full Name Benton, David. Institution Department of Psychology, University of Swansea, Swansea SA2 8PP, Wales, d.benton@swansea.ac.uk United Title The plausibility of sugar addiction and its role in obesity and eating disorders. Source Clinical Nutrition. 29(3):288-303, 2010 Jun. Journal Name Clinical Nutrition Country of Publication England Abstract Kingdom. BACKGROUND & AIMS: To consider the hypothesis that addiction to food, or more specifically sucrose, plays a role in obesity and eating disorders. METHODS: By considering the relevant literature a series of predictions were examined, derived from the hypothesis that addiction to sucrose consumption can develop. Fasting should increase food cravings, predominantly for sweet items; cravings should occur after an overnight fast; the obese should find sweetness particularly attractive; a high-sugar consumption should predispose to obesity. More specifically predictions based on the hypothesis that addiction to sugar is central to bingeing disorders were developed. Dieting should predate the development of bingeing; dietary style rather than psychological, social and economic factors should be predispose to eating disorders; sweet items should be preferentially consumed while bingeing; opioid antagonists should cause withdrawal symptoms; bingeing should develop at a younger age when there is a greater preference for sweetness. RESULTS: The above predications have in common that on no occasion was the behaviour predicted by an animal model of sucrose addiction supported by human studies. CONCLUSION: There is no support from the human literature for the hypothesis that sucrose may be physically addictive or that addiction to sugar plays a role in eating disorders. Copyright 2009 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved. Publication Type Journal Article. Date of Publication 2010 Jun Year of Publication 2010 Issue/Part 3 Volume 29 Page 288-303 HEALTH AND SOCIAL (INTERNET ADDICTION) <540> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20513862 Status In-Process Authors Fu KW. Chan WS. Wong PW. Yip PS. Authors Full Name Fu, King-wa. Chan, Wincy S C. Wong, Paul W C. Yip, Paul S F. Institution Journalism and Media Studies Centre, G24, Eliot Hall, Pokfulam Road,The University of Hong Kong, Hong Kong, China. kwfu@hku.hk Title Internet addiction: prevalence, discriminant validity and correlates among adolescents in Hong Kong. Source British Journal of Psychiatry. 196(6):486-92, 2010 Jun. Journal Name British Journal of Psychiatry Country of Publication England Abstract BACKGROUND: Despite increasing concern over the potential adverse effects of excessive internet use, especially in young people, there is some debate over its definition, magnitude and discriminant validity. AIMS: To examine the prevalence of adolescents' internet addiction in Hong Kong, China; to test its differentiation from other correlates; and to examine its relationships with correlates in a representative community sample of adolescents. METHOD: A two-wave panel household survey with 208 adolescents (aged 15-19 years) was conducted. Participants were asked to self-report their patterns of internet usage, symptoms of internet addiction, suicidal ideation, psychiatric symptoms and psychosocial conditions during the study period. RESULTS: The prevalence rate for having five or more symptoms of internet addiction was estimated to be 6.7% (95% CI 3.3-10.2). The discriminatory characteristic of internet addiction was marginally demonstrated. Positive dose-response relationships were found between the number of symptoms of internet addiction and 1-year changes in scores for suicidal ideation and depressive symptoms. CONCLUSIONS: Evidence supports the specificity of internet addiction and its symptoms seem to co-occur with individuals' suicidal ideation and depressive symptoms. Publication Type Journal Article. Date of Publication 2010 Jun Year of Publication 2010 Issue/Part 6 Volume 196 Page 486-92 HEALTH AND SOCIAL <558> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20432125 Status In-Process Authors Levine SB. Authors Full Name Levine, Stephen B. Institution Center for Marital and Sexual Health, Beachwood, Ohio 44122, USA. sbl2@case.edu Title What is sexual addiction? Comments Comment in: J Sex Marital Ther. 2010 May;36(3):276-81; PMID: 20432126 Source Journal of Sex & Marital Therapy. 36(3):261-75, 2010 May. Journal Name Journal of Sex & Marital Therapy Country of Publication England Abstract Married men labeled as sexual addicts seek help after being discovered to have had broken monogamy rules for sexual behavior through their use of masturbation, pornography, cybersex, commercial sex involvement, paraphilic pursuits, or affairs. This study analyzed the sexual patterns and dynamics of 30 men who presented to 1 clinician between 2005 and 2009. Their important differences were captured by a 6-category spectrum: (a) no sexual excess beyond breaking the spouse's restrictive rules (n = 2), (b) discovery of husband's longstanding sexual secrets (n = 5), (c) new discovery of the joys of commercial sex (n = 4), (d) the bizarre or paraphilic (n = 7), (e) alternate concept of normal masculinity (n = 5), and (f) spiraling psychological deterioration (n = 7). Only the men with a spiraling psychological deterioration-about 25% of the sample with sexual issues-could reasonably be described as having a sexual addiction. This group experienced significant psychological failures before the onset of their deterioration. Another 25% were adequately defined as paraphilic. Half of the sample was not adequately described using addiction, compulsivity, impulsivity, and relationship incapacity models. The authors discuss the implications of these findings for DSM-5 and treatment. Publication Type Journal Article. Date of Publication 2010 May Year of Publication 2010 Issue/Part 3 Volume 36 Page 261-75 HEALTH AND SOCIAL <559> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20432124 Status In-Process Authors Hook JN. Hook JP. Davis DE. Worthington EL Jr. Penberthy JK. Authors Full Name Hook, Joshua N. Hook, Jan P. Davis, Don E. Worthington, Everett L Jr. Penberthy, J Kim. Institution Department of Psychology, Virginia Commonwealth University, Richmond, Virginia 23284, USA. Title Measuring sexual addiction and compulsivity: a critical review of instruments. Source Journal of Sex & Marital Therapy. 36(3):227-60, 2010 May. Journal Name Journal of Sex & Marital Therapy Country of Publication England Abstract Research has proliferated on sexual addiction in recent years, and this has led to an increase in the instruments created to measure this construct. The authors review 17 instruments that have been created to assess sexual addiction, including self-report rating scales, self-report checklists, and clinician rating scales measuring symptoms of sexual addiction, as well as self-report rating scales measuring consequences associated with sexual addiction. For each instrument, the authors describe its structure, conceptual basis, and samples studied. They also evaluate the evidence for the reliability and validity of each instrument. The instruments vary widely in their psychometric properties. Many have been created recently, and others have only been studied in specific populations. For each group of instruments, the authors make recommendations for researchers and clinicians. Publication Type Journal Article. Date of Publication 2010 May Year of Publication 2010 Issue/Part 3 Volume 36 Page 227-60 HEALTH AND SOCIAL (INTERNET ADDICTION) <560> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20403001 Status In-Process Authors Tao R. Huang X. Wang J. Zhang H. Zhang Y. Li M. Authors Full Name Tao, Ran. Huang, Xiuqin. Wang, Jinan. Zhang, Huimin. Zhang, Ying. Li, Mengchen. Institution Addiction Medicine Centre, General Hospital of Beijing Military Region, Beijing 100700, China. bjptaoran@126.com Title Proposed diagnostic criteria for internet addiction. Comments Comment in: Addiction. 2010 Mar;105(3):565; PMID: 20403002 Source Addiction. 105(3):556-64, 2010 Mar. Journal Name Addiction Country of Publication England Abstract OBJECTIVE: The objective of this study was to develop diagnostic criteria for internet addiction disorder (IAD) and to evaluate the validity of our proposed diagnostic criteria for discriminating non-dependent from dependent internet use in the general population. METHODS: This study was conducted in three stages: the developmental stage (110 subjects in the survey group; 408 subjects in the training group), where items of the proposed diagnostic criteria were developed and tested; the validation stage (n = 405), where the proposed criteria were evaluated for criterion-related validity; and the clinical stage (n = 150), where the criteria and the global clinical impression of IAD were evaluated by more than one psychiatrist to determine inter-rater reliability. RESULTS: The proposed internet addiction diagnostic criteria consisted of symptom criterion (seven clinical symptoms of IAD), clinically significant impairment criterion (functional and psychosocial impairments), course criterion (duration of addiction lasting at least 3 months, with at least 6 hours of non-essential internet usage per day) and exclusion criterion (exclusion of dependency attributed to psychotic disorders). A diagnostic score of 2 + 1, where the first two symptoms (preoccupation and withdrawal symptoms) and at least one of the five other symptoms (tolerance, lack of control, continued excessive use despite knowledge of negative effects/affects, loss of interests excluding internet, and use of the internet to escape or relieve a dysphoric mood) was established. Inter-rater reliability was 98%. CONCLUSION: Our findings suggest that the proposed diagnostic criteria may be useful for the standardization of diagnostic criteria for IAD. Publication Type Journal Article. Research Support, Non-U.S. Gov't. Date of Publication 2010 Mar Year of Publication 2010 Issue/Part 3 Volume 105 Page 556-64 HEALTH AND SOCIAL <564> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20407974 Status In-Process Authors Lambert B. Scheiner M. Campbell D. Authors Full Name Lambert, Binta. Scheiner, Melissa. Campbell, Deborah. Institution Albert Einstein College of Medicine, Bronx, NY, USA. Title Ethical issues and addiction. Source Journal of Addictive Diseases. 29(2):164-74, 2010 Apr. Journal Name Journal of Addictive Diseases Country of Publication England Abstract The epidemic of substance abuse continues to pose a significant challenge to clinicians nationwide. Although there is a tendency to simply associate drug abuse with poverty, the problem affects every social stratum gender and race; and pregnant women are no exception. Caring for pregnant, substance-using women and their infants presents complex legal and ethical issues. Debate is ongoing about whether criminal penalties should be imposed on women based solely on their use of alcohol and other drugs during pregnancy. Furthermore, controversies persist about the rights and wishes of pregnant women versus the interests of their fetuses. For health professionals, conflict arises when the pregnant woman chooses behaviors that have the potential to harm the developing fetus. The ethical dilemma arises from competing autonomy-based and beneficence-based obligations to the maternal-fetal dyad. This chapter explores the ethics-based conflicts in the delivery of health care to drug abusing pregnant women. Publication Type Journal Article. Date of Publication 2010 Apr Year of Publication 2010 Issue/Part 2 Volume 29 Page 164-74 HEALTH AND SOCIAL <565> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20407973 Status In-Process Authors Kay A. Taylor TE. Barthwell AG. Wichelecki J. Leopold V. Authors Full Name Kay, Abigail. Taylor, Trusandra E. Barthwell, Andrea G. Wichelecki, Jana. Leopold, Vera. Institution Department of Psychiatry and Human Behavior-Division of Substance Abuse, Thomas Jefferson University Hospital, Philadelphia, PA, USA. Title Substance use and women's health. Source Journal of Addictive Diseases. 29(2):139-63, 2010 Apr. Journal Name Journal of Addictive Diseases Country of Publication England Abstract Scientific findings show that substance abuse in women yields a higher risk of a variety of health problems than substance abuse in men. Research suggests that women experience addiction telescoping when they abuse alcohol, tobacco, specific stimulants, and possibly opioids. Medical side effects also develop more rapidly in women than men when they abuse many substances. Cancer and cardiac complications, specifically, pose a significant threat for women who abuse almost all types of substances. However, the physical consequences are not the only ones women suffer when they engage in substance abuse. Research on substance abuse in women ties opioids to mood and anxiety disorders, heroin to neurological deficiencies, cocaine to immune system suppression, and alcohol to intimate partner abuse. Additionally, female substance abusers, on average, have a lower level of education and lower rates of employment. In light of these gender-specific concerns, physicians should give particular consideration to detecting substance abuse in women. Publication Type Journal Article. Date of Publication 2010 Apr Year of Publication 2010 Issue/Part 2 Volume 29 Page 139-63 HEALTH AND SOCIAL <566> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20407972 Status In-Process Authors Tuchman E. Authors Full Name Tuchman, Ellen. Institution Silver School of Social Work, New York University, New York, New York 10003, USA. ellen.tuchman@nyu.edu Title Women and addiction: the importance of gender issues in substance abuse research. Source Journal of Addictive Diseases. 29(2):127-38, 2010 Apr. Journal Name Journal of Addictive Diseases Country of Publication England Abstract Substance use was considered to be primarily a male problem, and many substance abuse studies are conducted with a predominance of male participants. However, recent substance abuse research indicates significant gender differences in the substance-related epidemiology, social factors and characteristics, biological responses, progressions to dependence, medical consequences, co-occurring psychiatric disorders, and barriers to treatment entry, retention, and completion. The epidemiology of women's drug use presents challenges separate from those raised by men's drug use. A convergence of evidence suggests that women with substance use disorders are more likely than men to face multiple barriers affecting access and entry to substance abuse treatment. Gender-specific medical problems as a result of the interplay of gender-specific drug use patterns and sex-related risk behaviors create an environment in which women are more vulnerable than men to human immunodeficiency virus. Individual characteristics and treatment approaches can differentially affect outcomes by gender. All of these differences have important clinical, treatment, and research implications. Publication Type Journal Article. Date of Publication 2010 Apr Year of Publication 2010 Issue/Part 2 Volume 29 Page 127-38 HEALTH AND SOCIAL <567> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20407971 Status In-Process Authors Kandall SR. Authors Full Name Kandall, Stephen R. Institution Albert Einstein College of Medicine, Bronx, NY, USA. sk1840@aol.com Title Women and drug addiction: a historical perspective. Source Journal of Addictive Diseases. 29(2):117-26, 2010 Apr. Journal Name Journal of Addictive Diseases Country of Publication England Abstract The history of women and addiction in America extends back more than 150 years. Although the true epidemiology of women and addiction has always been difficult to determine, the spectrum of female addicts extends well beyond those women who make sensationalistic headlines by "abandoning" or "battering" their children. Historically, female addiction has been largely the result of inappropriate overmedication practices by physicians and pharmacists, media manipulation, or individuals own attempts to cope with social or occupational barriers preventing equality and self-fulfillment. From the mid-nineteenth century, uneasy tolerance, social ostracism, vilification, persecution, and legal prosecution have grudgingly, but not completely, given way to more humane treatment opportunities in the setting of more enlightened comprehensive care. Publication Type Journal Article. Date of Publication 2010 Apr Year of Publication 2010 Issue/Part 2 Volume 29 Page 117-26 HEALTH AND SOCIAL <579> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20187928 Status In-Process Authors Macleod J. Copeland L. Hickman M. McKenzie J. Kimber J. De Angelis D. Robertson JR. Authors Full Name Macleod, John. Copeland, Lorraine. Hickman, Matthew. McKenzie, James. Kimber, Jo. De Angelis, Daniela. Robertson, James R. Institution Muirhouse Medical Group, 1 Muirhouse Avenue, Edinburgh EH44PL, UK. Title The Edinburgh Addiction Cohort: recruitment and follow-up of a primary care based sample of injection drug users and non drug-injecting controls. Source BMC Public Health. 10:101, 2010. Journal Name BMC Public Health Other ID Source: NLM. PMC2841670 Country of Publication England Abstract BACKGROUND: Injection drug use is an important public health problem. Epidemiological understanding of this problem is incomplete as longitudinal studies in the general population are difficult to undertake. In particular little is known about early life risk factors for later drug injection or about the life course of injection once established including the influence of medical and social interventions. METHODS: Individuals thought to be drug injectors were identified through a single primary medical care facility in Edinburgh between 1980 and 2006 and flagged with the General Registry Office. From October 2005 - October 2007, these cases were traced and invited to undergo interview assessment covering early life experience, substance use, health and social histories. Age and sex matched controls for confirmed cases (alive and dead) were later recruited through the same health facility. Controls for living cases completed the same structured interview schedule. Data were also collected on cases and controls through linkage to routine primary care records, death registrations, hospital contact statistics and police and prison records. All interviews were conducted with the knowledge and permission of the current GP. RESULTS: The initial cohort size was 814. At start of follow up 227 had died. Of the remaining 587: 20 had no contact details and 5 had embarked from the UK; 40 declined participation; 38 did not respond to invitations; 14 were excluded by their GP on health or social grounds and 22 had their contact details withheld by administrative authorities. 448 were interviewed of whom 16 denied injection and were excluded. Of 191 dead cases with medical records 4 were excluded as their records contained no evidence of injection. 5 interviewed cases died before follow up was concluded though these individuals were counted as "live" cases. 1 control per case (dead and alive) was recruited. Linkage to Scottish Morbidity Records data (available from 1981 onwards) on general acute inpatient and day cases, mental health inpatient and day cases and cancer was provided by Information Services, NHS Scotland, for all cases interviewed and all dead cases. The Scottish Prison Service provided records for 198 (46%) of cases interviewed, 48 cases not interviewed and 34 (18%) of dead cases. For a subsample of 100 interviewees a search of the Lothian and Borders police database was made for official criminal records and 94 had criminal records. Data linkage for controls is ongoing. CONCLUSIONS: Injecting drug users recruited from a community setting can be successfully followed-up through interviews and record linkage. Information from injecting cases is being analysed in terms of injecting patterns and possible influences on these. Comparisons between cases and controls will allow identification of possibly modifiable early life risk factors for drug injection and will also clarify the burden of disease associated with injection and the influence on this of different health and social interventions. Publication Type Journal Article. Research Support, Non-U.S. Gov't. Date of Publication 2010 Year of Publication 2010 Volume 10 Page 101 ALCOHOL <580> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 19929269 Status In-Process Authors Balldin J. Berggren U. Berglund K. Blennow K. Fahlke C. Zetterberg H. Authors Full Name Balldin, Jan. Berggren, Ulf. Berglund, Kristina. Blennow, Kaj. Fahlke, Claudia. Zetterberg, Henrik. Institution Institute of Clinical Neuroscience, Section of Psychiatry, Sahlgrenska Academy at Goteborg University Sweden, Goteborg, Sweden. Title Gamma-glutamyltransferase in alcohol use disorders: Modification of decision limits in relation to treatment goals? Source Scandinavian Journal of Clinical & Laboratory Investigation. 70(2):71-4, 2010 Apr. Journal Name Scandinavian Journal of Clinical & Laboratory Investigation Country of Publication England Abstract Serum gamma-glutamyltransferase (GGT) is recommended as a marker for alcohol use disorders by the Swedish National Guidelines for Addiction, although it has a low sensitivity and specificity. GGT is inexpensive and easily accessible but additional knowledge is required on how to use the marker in patients with various levels of alcohol intake. Levels of GGT were obtained from 37 male social drinkers (< 100 grams pure alcohol weekly) and 18 former alcohol-dependent males with long-term (6 +/- 5 years) abstinence. Reproducibility was calculated through repeated blood samplings. Mean serum activity of GGT, in former alcoholdependent males, was 0.26 microkat/L with an intra-class correlation coefficient of 0.85. In social drinkers, these figures were 0.34 microkat/L and 0.92, respectively. In treatment of males, with the goal of abstinence, upper reference limit is suggested to be 0.40 microkat/L. Goals of non-harmful drinking (< 100 grams weekly) suggest higher limits (0.62 microkat/L). Thirty percent increase of GGT should be suggestive of relapse. Publication Type Journal Article. Date of Publication 2010 Apr Year of Publication 2010 Issue/Part 2 Volume 70 Page 71-4 HEALTH AND SOCIAL <581> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20181248 Status In-Process Authors Grinman MN. Chiu S. Redelmeier DA. Levinson W. Kiss A. Tolomiczenko G. Cowan L. Hwang SW. Authors Full Name Grinman, Michelle N. Chiu, Shirley. Redelmeier, Donald A. Levinson, Wendy. Kiss, Alex. Tolomiczenko, George. Cowan, Laura. Hwang, Stephen W. Institution Centre for Research on Inner City Health, The Keenan Research Centre in the Li Ka Shing Knowledge Institute of St, Michael's Hospital, Toronto, Canada. michelle.grinman@utoronto.ca Title Drug problems among homeless individuals in Toronto, Canada: prevalence, drugs of choice, and relation to health status. Source BMC Public Health. 10:94, 2010. Journal Name BMC Public Health Other ID Source: NLM. PMC2841106 Country of Publication England Abstract BACKGROUND: Drug use is believed to be an important factor contributing to the poor health and increased mortality risk that has been widely observed among homeless individuals. The objective of this study was to determine the prevalence and characteristics of drug use among a representative sample of homeless individuals and to examine the association between drug problems and physical and mental health status. METHODS: Recruitment of 603 single men, 304 single women, and 284 adults with dependent children occurred at homeless shelters and meal programs in Toronto, Canada. Information was collected on demographic characteristics and patterns of drug use. The Addiction Severity Index was used to assess whether participants suffered from drug problems. Associations of drug problems with physical and mental health status (measured by the SF-12 scale) were examined using regression analyses. RESULTS: Forty percent of the study sample had drug problems in the last 30 days. These individuals were more likely to be single men and less educated than those without drug problems. They were also more likely to have become homeless at a younger age (mean 24.8 vs. 30.9 years) and for a longer duration (mean 4.8 vs. 2.9 years). Marijuana and cocaine were the most frequently used drugs in the past two years (40% and 27%, respectively). Drug problems within the last 30 days were associated with significantly poorer mental health status (-4.9 points, 95% CI -6.5 to -3.2) but not with poorer physical health status (-0.03 points, 95% CI -1.3 to 1.3)). CONCLUSIONS: Drug use is common among homeless individuals in Toronto. Current drug problems are associated with poorer mental health status but not with poorer physical health status. Publication Type Journal Article. Research Support, N.I.H., Extramural. Research Support, Non-U.S. Gov't. Date of Publication 2010 Year of Publication 2010 Volume 10 Page 94 HEALTH AND SOCIAL <583> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20181128 Status In-Data-Review Authors Strike C. Buchman DZ. Callaghan RC. Wender C. Anstice S. Lester B. Scrivo N. Luce J. Millson M. Authors Full Name Strike, Carol. Buchman, Daniel Z. Callaghan, Russell C. Wender, Cass. Anstice, Susan. Lester, Brian. Scrivo, Nick. Luce, Janine. Millson, Margaret. Institution Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario Canada. carol_strike@camh.net. Title Giving away used injection equipment: missed prevention message? Source Harm Reduction Journal. 7(1):2, 2010. Journal Name Harm Reduction Journal Other ID Source: NLM. PMC2832637 Country of Publication England Abstract ABSTRACT: BACKGROUND: Our objective was to examine factors associated with distributive injection equipment sharing and how needle exchange programs (NEPs) can help reduce distributive sharing among injection drug users (IDUs). METHODS: 145 English speaking Canadian IDUs ages 16 years and over who had injected in the past 30 days were recruited for a cross-sectional survey. Participants were asked about their socio-demographic characteristics, HIV risk behaviours, social support, drug treatment readiness, program satisfaction, health and social service use and NEP drug use. Bivariate statistics and logistic regression were used to characterize the population and examine correlates of sharing behaviour. RESULTS: More IDUs reported distributive sharing of cookers (45%) than needles (36%) or other types of equipment (water 36%; filters 29%; swabs 8%). Regression analyses revealed the following factors associated with distributing used cookers: a history of cocaine/crack injection, an Addiction Severity Index (ASI) score indicative of a mental health problem, and older than 30 years of age. Factors associated with giving away used water included: male, injected methadone, injected other stimulants and moved 3+ times in the past 6 months. Factors associated with giving away used filters included: injected cocaine/crack or stayed overnight on the street or other public place. Factors associated with giving away swabs included: an ASI mental health score indicative of a mental health problem, and HCV negative status. CONCLUSIONS: Our findings show that more IDUs give away cookers than needles or other injection equipment. While the results showed that correlates of sharing differed by piece of equipment, each point to distributive sharing by the most marginalized IDUs. Targeting prevention efforts to reduce equipment sharing in general, and cookers in particular is warranted to reduce use of contaminated equipment and viral transmission. Publication Type Journal Article. Date of Publication 2010 Year of Publication 2010 Issue/Part1 Volume 7 Page 2 HEALTH AND SOCIAL <585> Database Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations and Ovid MEDLINE(R) Unique Identifier 20047498 Status In-Process Authors Khalily MT. Authors Full Name Khalily, Muhammad Tahir. Institution Psychology Department and Addiction Treatment Unit, Mental Health Services, Roscommon, Ireland. khalily64@yahoo.com Title Developing a coordinated response to drug abuse in Pakistan. Source Journal of Interprofessional Care. 24(2):168-72, 2010 Mar. Journal Name Journal of Interprofessional Care Country of Publication England Abstract This paper describes moves towards the coordination of efforts to respond to the worsening drug abuse situation in Pakistan which affects all segments of society. The efforts reported seek to rectify inconsistencies in treatment policy resulting in unsatisfactory outcomes. Examples of collaborative strategies with encouraging results need further underpinning and expansion. There is, however, a lack of realization at the policy level of the need to effect changes in treatment formulated on a consistent and evidence-based approach. Policy has therefore been reviewed and proposals made for a comprehensive treatment strategy in line with international best practices to deal with this problem effectively and efficiently. Establishment of an addiction study centre at university level to continue professional and academic development is suggested. Publication Type Journal Article. Date of Publication 2010 Mar Year of Publication 2010 Issue/Part 2 Volume 24 Page 168-72