CURRICULUM VITAE
Name: Mervat Mostafa El-Enany
Date of birth: 21/06/1943
Address: 110 Nile Street, Doki -Giza-Egypt
Phone: (202)33352283
Mobile: 01223295283
Email: menany@hotmail.com
Qualifications:

Bachelor of Pharmaceutical Sciences, Very Good with Honor degree, Cairo University, May1965.

Master of Pharmaceutical Sciences degree in Organic Chemistry, Cairo University, 1969.

Doctor of Philosophy in Pharmaceutical Sciences. (Organic Chemistry), Cairo University, 1975.

Lecturer in Organic Chemistry Department, Faculty of Pharmacy, Cairo University,

Assistant Professor in Organic Chemistry, Cairo University, 1982.

Professor in Organic Chemistry, Cairo University 1990.
Current Employment and Teaching Experience:
2006- 2007:

Vice Dean for education and students affairs and Professor of Pharmaceutical Organic Chemistry at
Faculty of Pharmaceutical Sciences and Pharmaceutical Industries-Future University.
2003-2006:

Professor of Organic Chemistry at Faculty of Pharmacy, Cairo University.

Head of Organic Chemistry Department at Faculty of Pharmacy, Benisuef Branch, Cairo University.
2000- 2003:

Dean and Vice-Dean for Education and Students affairs at Faculty of Pharmacy Cairo University
(May-August2003).

Vice-Dean for Education and Students affairs at Faculty of Pharmacy Cairo University (2000-2003).

Head of Organic Chemistry Department Benisuef Branch Cairo University.

Professor of Organic Chemistry at Faculty of Pharmacy Cairo University.

Head of Quality Assurance Center at Faculty of Pharmacy, Cairo University.
1990-2000

Professor of Organic Chemistry at Faculty of Pharmacy Cairo University.

Head of Organic Chemistry Department Benisuef Branch Cairo University.
1996-1997
Sabbatical leave at Kanazawa University in Japan for Post Doctoral Research.
Dec.1996- June1996
Many sharings and contribution in different academic and student activities.
December 1990- July 1989:
Assistant Professor of Organic Chemistry in Faculty of Pharmacy Cairo
University.
July 1989-October 1984:
Associate Professor of Organic Chemistry in Pharmaceutical Chemistry Department, College of Pharmacy,
King Saud University.
1984- 1982:
Assistant Professor at the Organic Chemistry Department, Faculty of Pharmacy, Cairo University.
Course title:





Pharmaceutical organic chemistry I (Aliphatic compounds)
Pharmaceutical organic chemistry II (Aromatic compounds)
Pharmaceutical organic chemistry III (Heterocyclic compound)
Carbohyrates.
Stereochemistry
Areas of Research
1- Drug design based on the quantitative structure activity relationship (QSAR).
2- Synthesis and evaluation of certain pharmacologically active compounds.
3- Computational molecular dynamics using commercial software.
Key achievements
Academic services:
1- A member of Organic Chemistry Department, , Cairo University
2 A member of Computer Center of Faculty of Pharmacy, Cairo University)
3-- A member of Pharmaceutical Chemistry Department, Faculty of Pharmaceutical Sciences and
Parmaceutical Industries, Future University(2006-2013)..
4- A member of Pharmaceutical Chemistry Department, College of Pharmacy, and Science & Medical
studies Department for Women Students, King Saud University.
5- A member of researcher's evaluation committee, Faculty of Pharmacy, Cairo University.
6-A reviewer for Bull. Fac. Pharm. Cairo Univ., Bull.Fac.Pharm.Alazahar Univ., National Research Center,
and National Organization for Drug Control and Research (NODCAR)
7-Teaching Organic Chemistry in several governmental Universities (Cairo, Helwan, Suess Kanal and
King Saud), and private Universities (Future, 6 Octoberand M.U.S.T.)
8-The main secretary of the Future University International Conference on Pharmaceutical
Technologies (2012).
Visites to International Universities:
1. Visiting Professor,Nova University, Florida (USA) (2008).
2. Visiting Professor,Kanazawa University in Japan(1996).
Supervisory:
Supervision for Master and PHD Degree Theses at Faculty of Pharmacy Cairo University, King Saud
University, Benisuef University, National Research Center, and National Organization for Drug Control
and Research (NODCAR).
Publications:
1. Synthesis of Certain Sulphonylhydrazinopyrimidines.
Y.M. Abou-Zeid, M.M. El-Kerdawy, and M.M. El-Enany, Bull. Fac. Pharm., Cairo Univ., IX, No.1,
199-204 (1970).
2. Certain Aryl Sulphonyl Derivatives of Aryl Sulphonamidob-enzoylhydrazines.
M. M. El-Enany, M. M. El-Kerdawy, A. A. Abou-Ouf, and Y. M. Abou-Zeid. J. Pharm. Sci., U.A.R.,
12, No. 1, 17-23 (1971)
3. Attempted Preparation of Certain Benzodiazepines.
M. M. El-Enany, K.M. Ghoneim, and M. Khalifa., Bull. Fac. Pharm., Cairo Univ., XIV, No. 1, 29-37
(1975).
4. Synthesis of Certain Benzo-and Pyridodiazepines Likely to Possess Tranquilizing Effect.
M. M. El-Enany, K.M. Ghoneim and M. Khalifa., Die Pharmazie, 32, H. 2, 79-81 (1977).
5. Syntheseis of some Azaspirosulphonylureas and Thioureas Likely to Posssess Hypoglycemic
Activity.
F.A. El-Telbany and M. El-Enany., Bull. Fac. Pharm., Cairo Univ., XVIII, No. 2, 191-198 (1979)
6. Synthesis of Certain Styry1 Derivatives of Pharmaceutical Interst.
M.M. Said, M. M. El-Enany, and K.M. Ghoneim, Bull. Fac Pharm., Cairo Univ., XIX, No. 1, 1-10
(1980)
7. 5-Styryl-s-Triazolo (4,3-c) quinazolines
M. El-Enany and S.Botors., Die Pharmazie, 36, H. 1, 62 (1981).
8. Frontier Orbitals. Fact or Artefact? An SCF-PMO Study of some Diels-Alder Reactions.
M. El-Enany, B. Abd El-Fattah and S. El-Basil., Indian J. chem., 20 B, 592-594 (1981).
9. Nucleophilic Cleavage of 3, 5-Dioxo-2, 3, 4, 5- Tetrahydro-1, 4 Benzox-azepine.
A.N. Osman and M. El-Enany., J.Pharm. Sci., U.A.R., 22, No. 1-4, 1-7 (1981).
10. Synthesis of certain 3, 5-Disubstituted-2, 6- Dimethylpyridines of pharmaceutical Interest.
M.A. Mohamed, M.M. El-Enany, S. El. Basil and K.M. Ghoneim., J. Pharm. Sci., U.A.R., 22,
No.1-4, 395-302 (1982).
11. Cation Anion-Combination Reactions, Molecular Orbitals Calculations.
S.El-Basil, B. Abd El-Fattah, M.M. El-Enany, and N.Boulos., Revue Roumaine de Chimie 27, 8,
905-909 (1982).
12. Synthesis of certain 3, 5 -Disubstituted Lutidine Derivatives of Pharmaceutical Interst.
M.S. Mohames, M. M. El-Enany, S. El-Basil and K.M. Ghnoeim., Egypt. J. Pharm. Sci., 26, No.
1-4, 183-190 (1985).
13. Synthesis of certain Derivatives of 4-Aminoquinazolines.
S. Botros. M. M. El-Enany, F. M. Amine and L.N. Soliman., Bull. Fac. Pharm., Cairo Univ., XXV,
No 1, 41-50 (1986).
14. Synthesis of new Pyrido(1,2-a)Benzimidazoles as Potential Biologically Active Agents.
Mohamed Hammed, S. Abdel Meguid, M.M. El-Enany, Egypt. J. Chem., Vol. 29 No. 5, PP. 549553 (1986).
15. A Revisit to Molecular Path cods: Ordering, Comparability and Similarity of Banzenoid,
Nonbenzenoid and Monoradical Hydrocarbons.
S. El-Basil and M.M. El-Enany., Int. J. Quantum Chem., XXXII, 165-169 (1987).
16. Synthesis of Novel Series of 6-Methyl-2 (Substituted Methylthio) Pyrimidine Derivatives.
K.M. Ghoneim, F.A. El-Telbany, M. El-Enany, and K. Youssef., Egypt. J. Pharm. Sci., 28, No 1-4,
127-136 (1987).
17. Synthesis of Some Novel 2-Benzylthio-4-substituted Amino-6Antileukemic Activity.
Methylpyrimidines of Expected
K.G.Ghoneim, F.A.El-Telbany, M.ElEnany and K. Youssef. Oriental j. Chem. 4, No.3.297-300(1988)
18. Synthesis and Antibacterial activity 0f 1, 4-Disubstituted-2-Azetidinones
Faiza Siddieg El-Shafie and Mervat Mostafa El-Enany, Oriental j.Chem. 4, No. 3.297-300 (1988).
19. Synthesis and Antimicrobial activity of some Substituted Thieno [2, 3-d] pyrimidones
M. M. El- Enany and F.S. El-Shafie., Oriental J. Chem., 5. No 2, 114-117 (1989).
20. Synthesis and Biological Activity of Certain Substituted Thienopyrimidones.
S. H. El-zanfally, M. M. El-Enany, S.M. Roshdy and A. A. Monner., Oriental J. Chem., 5, No. 3,
242-246 (1989).
21. Synthesis and Antimicrobial activity of Novel Azomethinyl, Azetidnyl and Thiazolidinylpyrimidines.
K. M. Ghoneim, B. Abd El-Fattah, M.M. El-Enany, M.M. Kandeel and S. Megahed., Bull. Fac.
Pharm., Cairo Univ., 28, NO.1, 21-25 (1990)
22. Synthesis of Pharmacologically Interesting Thieno [2, 3-d] pyrimidones.
M. M. El-Enany, S.H. El-Zanfally, S.A. Roshdy and a.A.Moneer. Mans., J. Pharm. Sci., 6, No, 2,
10-18 (1990).
23. A Novel Approach to the Synthesis of Imidazo [1, 5-d] 1, 2, 4-Triazines of Potential Biological
Activity.
M. M. El-Enany and M. A. Shaaban., Bull. Fac. Pharm., Cairo Univ., 28, No. 2, 15-19 (1990).
24. Conformational Analysis of Certain Bis-substituted Diaminomethanes Based on Their Dipole
Moment Measurements.
M. Y. H. Essawi. M. M. El-Enany and G.R. Saad., Bull. Fac. Pharm., Cairo Univ., 28, No. 2, 21-24
(1990).
25. Synthesis and Antimicrobial Activity of certain Azole, Semi (or Thiosemi) Carbazone and Hyrazide
Derivatives of Pyrimidine.
K.M. Ghonein, B. Abd El-Fattah, M.M. El-Enany, M.M. Kandeel and S.A. Megahed.
Egypt. J. Pharm. Sci., 32, No. 1-2, PP. 181-190 (1991).
26. Synthesis and Antibacterial Activity of 4-Oxopyrolo [1,2-a] pyrimidine-3- Carboxylic Acid
Derivatives.
N.G. Hares. A.M. Al-Obaid, S.M.Bayomi and M.M. El-Enany, Egypt. J. Pharm., Sci., Vol. 23, No.
1-2, PP. 303-314 (1991).
27. Synthesis, Reactions and Antimicrobial Activity of certain Chalcone and Azlactone Derivatives of
Pyrimidine.
K.M. Ghoneim, B.Abd El-Fattah, M. M. El-Enany, M. M. Kandeed and S. Megahed., Egypt. J.
Pharm., Sci., Vol. 32, No. 1-2, PP. 315-324 (1991).
28. Stereochemistry of α-Cyanation of 4-Acetamido-1-Methylpiperidine.
M. M. El-Enany and M. Y. H. Essawy., Egypt. J. Pharm., Sci., Vol. 32, No. 3-4, PP. 761-766
(1991).
29. Synthesis of Certain Pyrimidine Derivatives of Possible Biological Importance.
M.M. El-Enany, L.N. Soliman, A.K. El-Ansary and H.H. Kadry
5th IBN Sina International Conference on Pure and Applied Heterocyclic Chemistry, 9-12
December 1995; p.145.
30. Synthesis of Certain Benzo[b]thieno [2, 3-d] Pyridazine Derivatives of Pharmaceutical interest.
Part I.
B. And El-Fattah, S. Salib, M. El-Enany, H. Ragab and A. Zher., 6th IBN Sina International
Conference on Pure and Applied Heterocyclic Chemistry, 13-16 December 1997; p.176.
31. Synthesis and Antimicrobial activity of certain pyrimidine derivatives.
M.M. El-Enany, L.N. Soliman, A.K. El-Ansary and H.H. Kadry
Bull. Fac. Pharm. Cairo Univ., vol 37, No. 3, 53-64 (199).
32. Synthesis of some novel pyridine nucleosides of expected chemotherapeutic effect.
Mervat M. Elenany, Galal E.H.Elgemeie, M. Mohsen Ismail and Iman K. Ahmed., Alexandria
second international conference of pharmaceutical sciences & technology (25-27 October 2001).
33.
Synthesis
of
6-Arylazo
and
6-Arylidenamino-5H
(2, 3-B) Pyridin-5ones as Potential Schistosomicidal Agents
(1)
Benzothiopyrano
Khaled R.El-Shemy, Ossama M. El-Badry, Mervat M.El-Enany and F.A.Ibid.*, Bull. Fac.
Pharm.Cairo Univ., Vol.39, No. 3 (2001).
34. Synthesis of 6-Substituted-5H (1) Benzothiopyrano(2, 3B) Pyridin-5-one Derivatives as potential
schistosomicidal agents
Khaled
R.El-Shemy,
Ossama
M.El-Badry,
Bull.Fac.Pharm.Cairo Univ., VOl.39, No.3 (2001).
Mervat
M.El-Enany
and
F.A.Ibid.,
35. Nucleic acid component and their analogues: A novel and efficient method for synthesis of a new
class of bipyridyl and biheterocyclic-N glycosides from pyridine-2-(1H) thione.
G.H. Gemeie, M.M.El-Enany, M.M.Ismail and E.K.Ahmed, Nucleosides, Nucleotides & Nucleic
acids Vol.21, Nos.6 & 477-493,2002
36. Allele and genotype frequencies of polymorphic cytochrome P450 (CYP2C9, 2C19, 2E1) and
dihydropyrimidine dehydrogenase (DPYD) in the Egyptian population.
S. Hamdy, M. Hiratsuka, K. Narahara, M. El-Enany, N. Moursi, M.S Ahmed, M. Mizugaki., Br.
J. Clin. Pharmacol. 2002, 53 (6): 596-603.
37- Allele and genotype frequencies of polymorphic DCP1, CETP, ADRB2 an HTR2A in the Egyptian
population
S. Hamdy, M. Hiratsuka, K. Narahara, M. El-Enany, N. Moursi, M. S.
Eur. J. Clin. Pharmacol. 2002, 58: 29-.
Ahmed, M. Mizugaki.,
38. Synthesis of certain novel pyridothiopyranoindazoles as potential DNA intercalators in cancer
chemotherapy
Khaled El-Shemy, Osama El-Badry, Sameha Roshdy and Mervat El-Enany., Bull.Fac.Pham.Cairo
Univ., Vol.42, No.2 (2004).
39. Allele and genotype frequencies of TPMT, NAT2, GST, SULT1A1 and MDR-1 in the Egyptian
population.
S. Hamdy, M. Hiratsuka, K. Narahara, N. Endo, M. El-Enany, N. Moursi, M.S. Ahmed, M.
Mizugaki, Br J Clin Pharmacol. 2003; 55(6):560-9.
40. Genotyping of four genetic polymorphisms in CYP1A2 gene in the Egyptian population,
S. Hamdy, M. Hiratsuka, K. Narahara, N. Endo, M. El-Enany, N. Moursi, M.S. Ahmed, M.
MizugakiBr, J Clin Pharmacol. 2003; 55(3):321-4.
41. Synthesis of Certain Novel Pyridothiopyranoindazoles as Potential DNA Intercalators in
Cancer Chemotherapy.
Mervat El-Enany, Sameha Roshdy, Ossama El-Badry and Khaled El-Shemy; Bull. Fac.
Pharm. Cairo Univ., Vol.42, No. 2, pp.25-31(2004).
42. Synthesis of 2-(4-Acylaminophenyl) Imidazo, and Oxazolopyridine Derivatives for
Antimicrobial Evaluation.
M. M. El-Enany, S. M. A. Roshdy, O.M. El-Badry and Eman E. K.; Bull. Fac. Pharm. Cairo
Univ., Vol.43, No. 3, pp.23-28(2005).
43. Design, Synthesis and Molecular Modeling of Certain Imidazo and Oxazolopyridine
derivatives of Biological Interest.
K. M. Mervat M. El-Enany, Sameha M. A. Roshdy, Osama M. El-Badry and Eman K. A.
Abdelall; Zagazig J. Pharm. Sci., Vol. 15, No. 2, pp. 38-52 (2006).
44. Synthesis, Anti-inflammatory, and Antimicrobial Activity of some Novel Pyrimido [4, 5]
quinolin-4-ones.
Abdel- Rahman B El-Gazzar, Mervat M El-Enany and Mahmoud N Mahmoud; Bioorganic&
Medicinal 16, 3261-3273 (2008).
45. Synthesis of certain [1] benzothieno [2, 3-d] pyridazine derivatives of pharmaceutical interest
(partI).
B.AbdEl-Fattah, S.Botros, M. El-Enany, Hamdy M. Ragab and Ashraf F. Zaher. Az. J.
Pharm. Sci., 38, 222, 2008.
46. Synthesis of certain [1] benzothieno [2, 3-d] pyridazine derivatives of pharmaceutical interest
(part II).
B. Abd El-Fattah, S. Botros, M. El-Enany, Hamdy M. Ragab and Ashraf F. Zaher. Az. J.
Pharm. Sci., 38, 233, 2008.
47. Synthesis of pyrazolo[3,4-b]pyridine and pyrido[2`,3`: 3,4] pyrazolo[1,5-a]pyrimidine derivatives.
Mervat M. El-Enany, Salwa E. M. El-Meligie, Nadia A. Abdou, Hala B. El-Nassan, J. Chem. Res., 34,
470-474, 2010.
48. Synthesis and antitumor activity of novel 6-aryl and 6-alkylpyrazolo [3, 4-d] pyrimidin-4-one derivatives
Mervat M. El-Enany, Mona M. Kamel, Omneya M. Khalil, Hala B. El-Nassan, Eur. J. Med. Chem., 45,
5286-5291, 2010
49. Synthesis and antitumor activity of novel pyrazolo[1,5‐a]pyrimidine derivatives
Mervat Mostafa El‐Enanya, Mona Monir Kamelb, Omneya Mahmoud Khalilb and Hala Bakr El‐
Nassanb, European Journal of Chemistry 2 (3) 331‐336, 2011.50
50. Synthesis And Antimicrobial Activity Of Novel 2-Substituted-1H-Benzimidazole Derivatives
Khaled R.A.Abdellatif1*, Heba A.H.Elshemy1, Ossama M.El-Badry2, Hamdy M.Ragab2,
Mervat M.El-Enany2
1
Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Benisuef University, 62111
Benisuef, (EGYPT)
2
Department of Organic Chemistry, Faculty of Pharmacy, Cairo University, Kasr-El-Eini street 11562
Cairo, (EGYPT)