PRODUCT INFORMATION D-(+)-Glyceraldehyde Item No. 16493 CAS Registry No.:453-17-8 Formal Name:(2R)-2,3-dihydroxy-propanal Synonyms: D-Glyceraldehyde, D-Glycerose, NSC 91534 MF:C3H6O3 FW:90.1 Purity: ≥95% Stability: ≥2 years at -20°C Supplied as: A neat oil CHO HO OH Laboratory Procedures For long term storage, we suggest that D-(+)-glyceraldehyde be stored as supplied at -20°C. It should be stable for at least two years. D-(+)-Glyceraldehyde is supplied as a neat oil. A stock solution may be made by dissolving the D-(+)-glyceraldehyde in the solvent of choice. D-(+)-Glyceraldehyde is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide, which should be purged with an inert gas. The solubility of D-(+)-glyceraldehyde in these solvents is approximately 30 mg/ml. Further dilutions of the stock solution into aqueous buffers or isotonic saline should be made prior to performing biological experiments. Ensure that the residual amount of organic solvent is insignificant, since organic solvents may have physiological effects at low concentrations. Organic solvent-free aqueous solutions of D-(+)-glyceraldehyde can be prepared by directly dissolving the neat oil in aqueous buffers. The solubility of D-(+)-glyceraldehyde in PBS, pH 7.2, is approximately 10 mg/ml. We do not recommend storing the aqueous solution for more than one day. Description D-(+)-Glyceraldehyde is an intermediate in carbohydrate metabolism. It is phosphorylated by triose kinase to produce D-glyceraldehyde 3-phosphate, an intermediate in glycolysis, gluconeogenesis, photosynthesis, and other metabolic pathways.1-3 References 1. Ronimus, R.S. and Morgan, H.W. Distribution and phylogenies of enzymes of the Embden-MeyerhofParnas pathway from archaea and hyperthermophilic bacteria support a gluconeogenic origin of metabolism. Archaea 1(3), 199-221 (2003). 2. Sullivan, D.T., MacIntyre, R., Fuda, N., et al. Analysis of glycolytic enzyme co-localization in Drosophila flight muscle. J. Exp. Biol. 206, 2031-2038 (2003). 3. Wolosiuk, R.A., Ballicora, M.A., and Hagelin, K. The reductive pentose phosphate cycle for photosynthetic CO2 assimilation: Enzyme modulation. FEBS J. 7, 622-637 (1993). WARNING THIS PRODUCT IS FOR RESEARCH ONLY - NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. SAFETY DATA This material should be considered hazardous until further information becomes available. Do not ingest, inhale, get in eyes, on skin, or on clothing. Wash thoroughly after handling. Before use, the user must review the complete Safety Data Sheet, which has been sent via email to your institution. WARRANTY AND LIMITATION OF REMEDY Buyer agrees to purchase the material subject to Cayman’s Terms and Conditions. Complete Terms and Conditions including Warranty and Limitation of Liability information can be found on our website. Copyright Cayman Chemical Company, 09/22/2015 CAYMAN CHEMICAL 1180 EAST ELLSWORTH RD ANN ARBOR, MI 48108 · USA PHONE: [800] 364-9897 [734] 971-3335 FAX: [734] 971-3640 CUSTSERV@CAYMANCHEM.COM WWW.CAYMANCHEM.COM