Interactions between L-arginine/L-arginine derivatives and
lysozyme and implications to their inhibition effects on
protein aggregateion
Mingtao Gao, Xiao-Yan Dong, Yan Sun*
Department of Biochemical Engineering and Key Laboratory of Systems
Bioengineering of the Ministry of Education, School of Chemical Engineering and
Technology, Tianjin University, Tianjin 300072, China
Supplementary data
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Figure S1. Thermodynamic parameters for the interactions between the additives and
lysozyme in the presence of 0.545 M GdnHCl. The H and S were obtained directly
from the data fittings, and the G was then calculated using the equation 𝐺 = 𝐻 −
𝑇𝑆. The numbers (1-3) represent the three binding sites.
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Figure S2. Mass spectrum of GdnHCl in aqueous solution at 0.545 M.
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Figure S3. Mass spectrum of Arg (0.2 M) in the aqueous solution of 0.545 M
GdnHCl.
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Figure S4. Mass spectrum of HArg (0.2 M) in the aqueous solution of 0.545 M
GdnHCl.
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Figure S5. Mass spectrum of ArgME (0.2 M) in the aqueous solution of 0.545 M
GdnHCl.
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Figure S6. Mass spectrum of ArgEE (0.2 M) in the aqueous solution of 0.545 M
GdnHCl.
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