Chemistry 20 – Introductory Organic and Biochemistry I. Course

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Chemistry 20 – Introductory Organic and Biochemistry

Dr. Behrang Madani

Email: beh_madani@hotmail.com

Web page: http://instruction2.mtsac.edu/bmadani/

Spring 2013 Lecture: TTh: 3:00 – 4:25pm in 7-1201

Lecture: T: 3:00 – 7:20pm in 7-1201

Laboratory: Th: 5:00 – 9:15pm in 7-2123

I. Course Description:

Introductory Organic and Biochemistry (5 units):

Chemistry 20 is an introductory organic and biochemistry course designed for science students who have successfully completed a previous chemistry course (a passing grade in Chem 10 or Chem 40).

As such it is expected that students will have a fundamental knowledge of atomic structure, bonding, nomenclature, molecular geometry, polarity, and acid-base. This course will introduce nomenclature, structure, function, and reactions of major classes of organic compounds, structure and function of biomolecules, and metabolic pathways. Success in this course will depend on attending class regularly and on time, reading the text/lab manual before class, being prepared to be engaged in the day’s activities, devoting the necessary amount of time to do homework and study for quizzes/exams, and taking the initiative in seeking help when needed.

Prerequisite : Chem 10 or Chem 40.

II. Required Materials:

1. Lecture:

1.1. Introduction to Organic and Biochemistry, 8 th

edition, by Bettelheim et al.

(ISBN-10: 1133109764)

1.2. Solution and study guides (optional but recommended).

I suggest using this textbook as reference: Chemistry: Introduction to General Organic & Biochemistry,

10 th

edition, by Karen Timberlake.

2. Laboratory:

2.1. Chemistry 20 Laboratory Manual, 8 th

edition by DiMauro

2.2. Laboratory Netbook with carbonless pages

2.3. Safety goggles that enclose the area around the eyes completely (from the top and sides)

2.4. Matches, Dishwashing liquid detergent

2.5. Closed toed shoes

2.6. Lab apron/coat and model building set (optional but recommended)

Note: Lab coat is optional. If you do not have a lab coat, wear a normal cloth (you will work with some materials that can ruin your cloths).

III. Attendance:

Regular attendance is an absolute necessity in this course. Students who do not regularly attend and participate are not successful. As stated previously, students who are absent to lecture and/or lab for 6 times may be dropped from the course. If it is after the drop date you will no longer accumulate credit for work done and will likely get an F depending on when this occurs. If you should be absent for unavoidable reasons, you must check with me before. No make-ups are allowed for missed class work, quizzes, or exams.

IV. Special Needs (Accommodations for disabilities):

Student with disabilities who believe they may need accommodation in this class are encouraged to contact me immediately. More help can be obtained from Mt. SAC Disabled Students Programs and

Services in Building 9C or at 909-594-5611, x4970.

V. Student evaluation and Grading:

Homework & problem sets

Laboratory experiments and assignments

Quizzes

Exams

Final exam

10 %

30 %

10 %

35 %

15 %

Note: You have 4 exams including the final exam (see your course schedule). Some practice exams will be made available before each exam. Only non-programmable scientific calculators are allowed on exams.

Note: your lowest test grade, excluding the final test grade, will be dropped. If you are absent for a test, then the missed test will be test dropped.

Note: There are 4 quizzes during the semester (see your course schedule). However; some other pop quizzes will appear throughout the course. You won’t be announced in advance for these kinds of quiz, so be prepared before each class!!!

Your final grade will be assigned based on following manner:

90 – 100 % A

80 – 89 %

70 – 79 %

60 – 69 %

Below 60 %

B

C

D

F

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Cheating:

It is not allowed in any form and such will earn the student an automatic zero. A report of the incident will be forwarded to the Dean of the Natural Science Division and becomes a permanent part of a student’s profile. Copying homework or lab report from others or allowing others to copy your assignments is also unacceptable and considered cheating (very similar versions of the same homework or lab reports will not be graded).

VI. Assignments:

Homework is due at the beginning of the class meeting following the day we finish discussing the chapter in lecture. I will be assigning many even and/or odd numbered problems. The goal is to give you sufficient practice to enable you to be successful on the examinations. The assigned problems have to be complete and correct (otherwise, you will not receive full credit). For each assignment, I will select five assigned problems randomly and I will give you the credit according to the correctness and the accuracy of these chosen problems. You must show all work for credit (you cannot simply copy the answers in the text) and the final answer must be circled or highlighted.

Note: Late homework, lab reports, projects, etc will not be accepted (except when absent in which you may only turn in work the day you return) and you will have earned zero for that work.

Note: always staple your multipage assignment together or point will be taken off.

VII. Policies and remarks:

Arriving late or leaving early is disruptive for other students and will count as ½ hour absent for lecture and 1 hour absent for lab. This means every 3 lecture or 3 lab late equals 1 absence. No extra time is given on quizzes or exams for tardies.

Arriving on time to lab is crucial in order to maintain a safe working environment. The instructor will begin the laboratory period by clarifying and/or modifying the procedure including safety precautions and the proper disposal of laboratory waste. Students who miss this important information can compromise the safety of everyone in the class. Therefore, students who arrive late may not be allowed to perform the experiment.

Cell phones should be off or placed in vibrate mode during class. The ringing of cell phones interferes with instruction and concentration of other students. The students should not use their cell phones in class or leave the class to answer the phone. In order to preserve a positive environment, the student will be asked to leave for the rest of period and she/he will be counted as absent for that day.

Computer Policy: Students are expected to adhere to the Chemistry Department computer policies in order to maintain proper working of the equipment as well as preventing misuse of the department computers.

Tutoring services: Students should take advantage of free tutoring available through the Learning

Assistance Center (LAC), in Building 6. Announcements regarding tutoring schedule will be given in class.

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VIII. Some important dates:

Mar. 11

Last day to drop from semester length classes without receiving "W" grades.

May 3

Last week to withdraw from Fall Semester.

Jun. 13

Final Exam (5:00 – 7:00pm)

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LABORATORY COURSE INFORMATION

The laboratory experiments are designed to complement and reinforce chemical concepts learned in lecture and to provide the students an opportunity to gain confidence and specific laboratory skills that will allow them to work safely and efficiently in any chemistry lab. Students are required to attend a 4.3-hours lab session per week. Class will begin on time and students are expected to remain in lab for the entire period, even if the experiment is completed prior to the end of class. Students should bring all required items (textbook, lab manual, lab notebook, pen, calculator, etc) to all lab sessions.

Please bring safety goggles, lab coat/apron, matches, dishwashing detergent, and dishtowel to the 1 st

lab meeting.

These items should be left in the lab locker for the entire semester. You may also leave an extra pair of closed-toe shoes and lab coat or apron, if desired.

Each lab session will begin with a short discussion of the experiment, including any changes to the procedure, waste disposal, safety precautions, and demonstration on the proper use of equipment. Students will then conduct the experiment individually (sometimes in pairs/groups), collect data, and at the conclusion of the experiment, will begin data analysis for the lab report.

Attendance: Students who miss a lab session will earn zero for that lab experiment and they cannot copy data from another student to write the lab report. Sharing of data without actually performing the experiment is considered a violation of the cheating policy and will result in a grade of “0” for that experiment for both the student who copied and the student who shared the data. As stated previously, students who are absent to lecture and/or lab for 6 times may be dropped from the course.

Tardiness not only interrupts the learning environment but also creates extra hazard for all students since critical information regarding safety features, proper waste disposal, and changes to the experiment may be missed.

Students who are late to the lab will have points deducted from their lab grade and those who arrive after safety information has been covered, may not be permitted to perform that experiment and may receive a “0” for the entire experiment.

Safety: Maintaining a safe environment in the laboratory is essential. All safety rules must be followed at all times! The chart in the back of the lab and the safety video shown during the first week of class provide a complete list of safety procedures and guidelines that will be followed in this class. Any student who flagrantly disregards safety rules or creates an unsafe situation will immediately be dismissed from class for the day and receive a “0” for the day’s work. No make-up will be allowed. Below is a selected list of safety rules.

Be prepared by reading the experiment, taking special note of safety precautions, before coming to lab.

Students must dress appropriately for lab (wear safety goggles, closed-toed shoes, lab aprons/coats, tie long hair back, remove bulky clothing and dangling jewelry).

Eating food, chewing gum, and drinking (even water) are never allowed in the lab.

Unauthorized experiments, such as mixing chemicals or adding extra quantities, are never allowed under any circumstances.

Laboratory waste must be disposed of according to instructions. It must never be poured down the drain or into a trashcan unless specifically instructed to do so.

Excess reagents must be disposed of in the proper waste container, never returned to the original bottle.

Broken glassware must be disposed of in the blue can in the back of the lab. It should never be placed in a regular laboratory trashcan.

Report all spills and accidents to the instructor immediately.

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Checking into/out of the Locker: See the CHEM 20 Lab Manual for instructions for checking into/out the locker.

Students are responsible for the content of their lockers. Broken and/or missing glassware/item may result in loss of points.

Laboratory Grading: Each experiment will be worth a maximum of 100 points, distributed as outlined below. See the sample rubric for lab grading.

Pre-lab assignment/Notebook 25 points

In-Lab Participation/Notebook 25 points

Post-Lab Lab report 50 points

Guidelines for the laboratory notebook: Each student is required to maintain a laboratory notebook (bound and contains consecutively numbered pressure-sensitive duplicate sets of graph papers) as a permanent record of his/her laboratory work, reflecting the work done in real time in the lab. Maintaining a proper laboratory notebook is essential when working in a lab where an accurate recording of all procedures, observations, and data must be made. Completeness and accuracy in experimental records allow the experimenter to prepare lab reports and also allow others to reproduce the experiments. Below are the specific guidelines when recording in the lab notebook.

1.

All entries into the lab notebook must be made neatly and legibly with a blue or black ballpoint pen .

2.

If mistakes are made, draw a single line through it (ex: error) and write the correction above or beside the mistake (no erasing, white-out, or scribbling). In no cases are the pages containing errors to be torn out.

3.

Each page in the lab notebook should have the student’s name, date, title, and number of the experiment. Each experiment should be started on a new page.

4.

All data and observations must be recorded directly into the lab notebook at the time the experiment is in progress, not on scraps of paper at first and to be later transferred into the lab notebook.

5.

The cover page of the notebook should contain the student name, course and section number, instructor name, semester and year.

6.

The next page will be used as a Table of Contents (some notebooks include a Table of Contents.) It will contain the title of the experiment and the number of the first page of the experiment. The table of contents should be updated each time an experiment is performed.

Pre-laboratory Assignment/Notebook: Each experiment will have a pre-laboratory (pre-lab) assignment that the students are expected to complete BEFORE coming to the lab session. The pre-lab assignment, which will vary in length and complexity with different experiments, must be done in the laboratory notebook on the first page for that experiment using the guidelines given . The pre-lab assignment will be checked for completion at the beginning of the class. Students who did not completed the pre-lab assignment at the beginning of the period will not be allowed to work in the lab until it is completed and may be given a “0” for the entire lab.

Components of the Pre-lab assignment:

1.

Record the student’s name, date of the experiment, title, and number of the experiment at the top of the lab notebook. In many notebooks, there is a pre-set box for the heading.

2.

Pre-lab Questions: Write the answers to the assigned questions in the lab notebook using complete sentences. You may be asked to share the answers to these questions in class.

3.

Purpose : Write the objective/purpose for the experiment in short sentences or phrases. If there is more than one objective, list them in a column.

4.

Safety Features: List safety precautions and disposal for each part of the procedure.

5.

Materials: List all required equipment, instruments, and chemicals (including quantities) needed to perform the experiment.

6.

Procedure: Summarize the procedure in numbered steps on the left hand side of the page. The procedure should be thorough enough for someone else to repeat the experiment but DO NOT COPY the lab manual verbatim.

7.

Observation/Data: Write the heading “Observation/Data” on the right hand side of the page, next to the Procedure heading. It is recommended (although not mandatory) that you create empty tables (with labels and units) that you will fill in as you do the experiment. Reading through the procedure and looking at the Data Summary and Analysis sheets will help you determine what data needs to be collected.

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In-Lab participation/Notebook: Students are expected to conduct the experiment individually, unless otherwise directed. Students are to work efficiently and safely when performing experiment and are responsible for lab clean up. All appropriate observations and data (with the correct number of significant figures and units where relevant) should be recorded into the data table in the notebook (not on scratch pieces of paper, paper towel, etc) while conducting the experiment. Remember that if something is not recorded in the lab notebook, it cannot be used in the lab report.

The student will turn in stapled duplicate copies of all the pages pertaining to the experiment at the conclusion of the experiment. No additional recording in the lab notebook is permitted once the copies are turned in. Students are graded on successful completion of the experiment, recording all appropriate observations and data, and adherence to lab safety rules and expectations.

Post-Lab Laboratory report: Upon completion of the experiment, students will use the data/observation recorded in their lab notebooks to complete the Data Summary and Analysis sheets found in the lab manual. These should be completed neatly and legibly using black or blue pen. For some experiments, students will type a Conclusion according to the following guidelines: In a paragraph form (using past tense) briefly restate the objective of the experiment that was accomplished and the results that were obtained. A brief experimental procedure including the number of trials and experimental results for each trial as well as the average (with percent errors where relevant) should be included. The conclusion should have enough information so that someone who reads it without having read any pre-lab or in-lab pages in the notebook should be able to answer three questions regarding the experiment: what was accomplished, how was it accomplished and what was the significance of the accomplishment. The lab report (Data Summary/Analysis and Conclusion) is due 1 week from the date of the completion of the experiment.

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CHEM 20 LECTURE, MODEL ACTIVITY, LAB SCHEDULE—Madani—Spring 2013

(This schedule is tentative and is subject to change. Any changes made will be announced in class.)

Week Date Lecture — Room 7-1201

TTh (3:00-4:25pm)

1 2/26

2/28

Intro. /Lewis Structures

Ch. 1 – Organic Chemistry

2

3

3/5

3/7

3/12

3/14

Ch. 2 – Alkanes

Ch. 2 – Alkanes

Ch. 3 – Alkenes and Alkynes

Ch. 4 – Benzenes

Model Activity — Room 7-1201

T (5:00-7:20pm)

Model A – Molecular Structure

Model B – Alkanes

Model C – Unsaturated Hydrocarbons

Quiz 1

Lab — Room 7-2123

Th (5:00-9:15pm)

Check-in, Safety, Exp. #1 – Polarity

Exp. #2 – Physical Properties of Hydrocarbons

Exp. #3 – Chemical Properties of Hydrocarbon

4

5

6

7

8

9

10

11

12

4/9

4/11

4/16

4/18

4/23

4/25

3/19

3/21

3/26

3/28

4/2

4/4

4/30

4/2

4/7

4/9

Ch. 5 – Alcohols

Review for Exam 1

Ch. 5 – Alcohols

Ch. 9 – Aldehydes and Ketones

Ch. 10 – Carboxylic Acids

Ch. 11 – Carboxylic Derivatives

Ch. 8 – Amines

Ch. 12 – Lipids

Model J – Lipids

Ch. 13 – Carbohydrates

Ch. 13 – Carbohydrates

Ch. 14 – Proteins

Ch. 14 – Proteins

Ch. 15 – Enzymes

Ch. 15 – Enzymes

Review for Exam 3

Model D – Rxn of Hydrocarbons

Exam 1 (Ch. 1-4)

Model E – Structure of Alcohols

Model G – Amines, Quiz 2

Review for Exam 2

Exam 2 (1-11 except: 6 &7)

PowerPoint presentation

Model I – Proteins, Quiz 3

Model H – Carbohydrates

Exp. #4 – Identity of an Unknown Organic Compound –

Hydrocarbon version

Exp. #5 – Properties of Oxygen-Containing Compounds

Exp. #6 – Esters, Model F – Carbonyl Structure and

Rxns

Exp. #4 – Identity of an Unknown Organic Compound –

Oxygen containing compound version

Exp. #8 – Polymers

Exp. #7 – Saponification

Exp. #8 – Reactions of Carbohydrates

Exp. #9 – Catalase

13

14

15

16

4/14

4/16

4/21

4/23

4/28

4/30

5/4

5/6

5/11

5/13

Ch. 17 – Nucleotides

Ch. 17 – Nucleotides

Ch. 18 – Gene Expression

Ch. 19 – Bioenergetics

Ch. 19 – Bioenergetics

Ch. 20 – Catabolic Pathways

Ch. 21 – Biosynthetic Pathways

Review for final

Check-out/Assessment

Model K – Nucleic Acids

Quiz 4

--

, Model L – Gene Expression

Ch. 21 – Biosynthetic Pathways

Exam 3 (Ch. 12-15)

Exp. #10 – Extraction & Separation of Plant Pigments

Exp. #11 – Synthesis and Analysis of Aspirin-Part I

Exp. #11 – Synthesis and Analysis of Aspirin-Part II

Exam 4 Final Exam (Ch. 17-21) >>> 5:00-7:00pm

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