The Cell Cycle and Mitosis SNC2P The Cell Cycle Every hour, approximately 1 billion of your cells die – but approximately 1 billion cells are created in a process of cell division called mitosis. Interphase The cell prepares for cell division by growing and by making copies of its organelles and DNA. Interphase The cell prepares for cell division by growing and by making copies of its organelles and DNA. This stage of the cell cycle is called interphase. Prophase During the first phase of mitosis, prophase, the DNA condenses into chromosomes and the nucleus disintegrates. A framework called the mitotic spindle forms. Metaphase Then the chromosomes line up in the middle of the cell. This is metaphase. Anaphase During anaphase, the chromosomes separate and are pulled to opposite ends of the cell. Telophase and Cytokinesis In the last stage of mitosis, telophase, the cell divides the cytoplasm into two portions. Telophase and Cytokinesis In the last stage of mitosis, telophase, the cell divides the cytoplasm into two portions. The final separation of the cytoplasm into two distinct cells is called cytokinesis. Rate of Mitosis Different parts of an organism experience different rates of mitosis (e.g. an onion root tip is where growth occurs and therefore the cells divide frequently, every 12 – 36 hours). Rate of Mitosis In humans, skin cells (that brush off) or intestinal cells (that are broken down by the digestive process) have high rates of mitosis, but red blood cells may last for months. human skin cells Apoptosis The controlled death of a cell that is no longer useful (e.g. white blood cells post-infection) or is damaged is called apoptosis. Your Task Your task will be to identify the structures that will allow you to identify each phase and then to observe mitosis in a prepared slide of an onion root tip.