Downloaded from http://bmjopen.bmj.com/ on March 5, 2016 - Published by group.bmj.com PEER REVIEW HISTORY BMJ Open publishes all reviews undertaken for accepted manuscripts. Reviewers are asked to complete a checklist review form (see an example) and are provided with free text boxes to elaborate on their assessment. These free text comments are reproduced below. Some articles will have been accepted based in part or entirely on reviews undertaken for other BMJ Group journals. These will be reproduced where possible. ARTICLE DETAILS TITLE (PROVISIONAL) AUTHORS Lay perspectives of successful ageing: A systematic review and meta-ethnography Cosco, Theodore; Prina, Matthew; Perales, Jaime; Stephan, Blossom; Brayne, Carol VERSION 1 - REVIEW REVIEWER REVIEW RETURNED THE STUDY RESULTS & CONCLUSIONS GENERAL COMMENTS Eric Brunner Reader in epidemiology and public health UCL 07-Mar-2013 What is the definition of a qualitative study? Commonly, it means an open-ended or semi-open-ended question format. Is that your definition? The abstract should contain the psychosocial factors commonly identified by lay people. The biomedical concepts of successful ageing are not well defined. The second version of this article is modified to focus on lay perspectives of successful ageing. The previous version compared lay and researcher perspectives, and therefore the article is simplified. This is a helpful change because the paper is less hybrid. The aim is now „to augment the largely quantitatively dominated SA literature with insights from qualitative research‟. The search strategy is clearly specified. It would be useful to know if the terms <quality of life> and <ageing> identify additional literature. The process of study selection usually includes title screening, but this was not done here. It would be helpful to have a little more detail on the data extraction method relating to „the ranked importance of SA components and the percentage of individuals listing each SA component‟ (p.7). This reviewer is new to the term „metaethnographic‟ and it would be useful, I am sure for many readers, to have an explanation of the method that was employed. Discussion of the findings starts with a bold assertion of „divergence from traditional biomedical conceptualizations of SA‟ (p.10). This statement needs empirical back-up. The Discussion presents some interesting perspectives on the scope of the concepts underlying SA. I recommend strongly that the number of discouraging comments concerning biomedical views on ageing is reduced, and where they are retained they should be based on evidence rather than prejudice. Why seek to publish in a biomedical journal and to antagonise the core readership? Specific points 1. What is the definition of a qualitative study? Commonly, it means an open-ended or semi-open-ended question format. Is that your definition? 2. Please refer to evidence to support the claim that research on SA Downloaded from http://bmjopen.bmj.com/ on March 5, 2016 - Published by group.bmj.com is dominated by quantitative studies (p.5). 3. The term „healthy ageing‟ is used in the Introduction. Please provide some indications of the difference between this term and SA. 4. The search strategy identified 5336 articles, not 10580. Please correct the flow diagram. 5. Please consider a better term e.g. qualitative, rather than exploratory. A study with >1500 participants is not really exploratory. REVIEWER REVIEW RETURNED THE STUDY RESULTS & CONCLUSIONS Tim Windsor Australian Research Council Future Fellow Flinders University of South Australia Australia No competing interests 08-Mar-2013 This manuscript reports a systematic review of qualitative research concerned with lay perspectives on successful ageing (SA). The question of what it means to age „successfully‟ is important from a social policy perspective, and the authors appear to have done a good job of identifying relevant qualitative studies, and emergent themes across the studies. Despite these strengths, there were a number of limitations that left me unconvinced as to whether the manuscript (at least in its current form) has the potential to make a significant contribution to the literature. First, there was no strong case made in the introduction as to why it is important to consider lay perspectives, and why these would be expected to be different to researcher-driven perspectives. The rather broad claim is made that “through the acknowledgement of qualitative data, quantitative studies may be better informed, with increased practical relevance and impact”. How exactly do qualitative studies increase practical relevance and impact? Is there an appropriate citation to support this claim? The authors distinguish their review from that of Hung et al on the grounds that the Hung paper focuses on “healthy ageing”, whereas the current manuscript focuses on SA. It is not clear what this semantic distinction represents, particularly as the authors note that conceptions of successful ageing often have a biomedical focus. This is further complicated by the fact that “healthy ageing” was included as a synonym for “successful ageing” in the search strategy (p. 6). Bowling and Dieppe‟s (2005) review of researcher- and laydefinitions of successful ageing in BMJ should be cited, and how the current study makes an additional contribution clarified. A number of successful ageing synonyms were included in the search strategy, however it is later noted that studies discussing synonyms of SA, but without specific reference to SA were excluded from the review. This left me unsure as to why the synonyms were used. Some more detail on the foundations of the “metaethnographic framework” and how this is applied in identifying and organizing themes would be helpful for the reader unfamiliar with qualitative methods. It was not clear to me what the term „items‟ (p. 8) referred to, and whether „item‟ is interchangeable with „theme‟. I would usually think of items as specific questions used in survey research. On p. 9 the authors indicate that physical functioning/disability was the most often mentioned of the constituent components of SA. This seems Downloaded from http://bmjopen.bmj.com/ on March 5, 2016 - Published by group.bmj.com inconsistent with the abstract, and Figure 5. The results reported in the text of p.9 indicate that several themes (e.g., engagement) were identified by high percentages of studies (> 80%). However the maximum percentage value on the Y axis of Figure 5 is 20%. I was unable to work out how the text on p. 9 mapped onto the results of Figure 5. The main theme that is emphasized throughout the discussion is that biomedical models of SA are not sufficient, and that psychosocial components are also important to consider. This is an important point, but it seems to me that it is one already wellestablished in the SA literature (e.g., Bowling & Dieppe, 2005). Even Rowe and Kahn‟s (1997) model, despite its biomedical focus, acknowledges the importance of several psychosocial attributes including supportive social relationships and self-efficacy under the broader heading of „engagement‟. I felt that more was needed in the discussion to demonstrate how this study makes a unique contribution. References Bowling, A., & Dieppe, P. (2005). What is successful ageing and who should define it? BMJ, 331, 1548-1551. Rowe, J. W., & Kahn, R. L. (1997). Successful aging. The Gerontologist, 37, 433-440 VERSION 1 – AUTHOR RESPONSE Reviewer: Eric Brunner Reader in epidemiology and public health UCL What is the definition of a qualitative study? Commonly, it means an open-ended or semi-open-ended question format. Is that your definition? - Our definition of qualitative research has been clarified as suggested. “Studies were considered to be qualitative if participants were asked open-ended or semi-open ended question(s). The abstract should contain the psychosocial factors commonly identified by lay people. - Examples of psychosocial factors commonly identified by lay people have been added o the abstract. “Laypersons identified psychosocial components, notably engagement, e.g. social engagement, and personal resources, e.g. attitude, as integral components of SA in more studies than “physiological” components, such as longevity or physical functioning.” The biomedical concepts of successful ageing are not well defined. - The underpinnings of biomedical conceptualisations of successful ageing have been clarified. “The most popular model of SA, Rowe & Kahn‟s 2 3 conceptualisation of SA is primarily biomedical. This and other biomedical models of SA focus on physiological or cognitive aspects of health, as captured by metrics such as the Mini Mental State Exam 4or the Activities of Daily Living scale 5 . Rowe & Kahn‟s 2 3 model suggests that high cognitive/physical functioning, low risk of illness, and active engagement comprise SA. The second version of this article is modified to focus on lay perspectives of successful ageing. The previous version compared lay and researcher perspectives, and therefore the article is simplified. Downloaded from http://bmjopen.bmj.com/ on March 5, 2016 - Published by group.bmj.com This is a helpful change because the paper is less hybrid. The aim is now „to augment the largely quantitatively dominated SA literature with insights from qualitative research‟. The search strategy is clearly specified. It would be useful to know if the terms and identify additional literature. - While the addition of “quality of life” and “ageing” does identify additional literature. The objective of the current study is to provide a snapshot of the existing literature on lay perspectives of successful ageing. Therefore, the addition of these terms falls outside of the scope of the current study. The process of study selection usually includes title screening, but this was not done here. - During the screening process, labelled “abstract review” in the first draft, titles were also screened; however this was not included in the text. Thank you for identifying this omission. The text has been revised to indicate that titles and abstracts were screened. “Title and abstract review was conducted (TDC & JP), to identify relevant articles for full-text extraction.” It would be helpful to have a little more detail on the data extraction method relating to „the ranked importance of SA components and the percentage of individuals listing each SA component‟ (p.7). - The data extraction methods for SA components and ranked importance of SA components has been clarified. “Information regarding the definitions and components of SA were extracted from authors‟ descriptions and syntheses of participants‟ responses as well as direct quotes from study participants. Where possible, the percentage of respondents referencing each SA component in a given study was noted. In studies where participants ranked the relative importance of each SA component, these data were recorded. This reviewer is new to the term „meta-ethnographic‟ and it would be useful, I am sure for many readers, to have an explanation of the method that was employed. - A further explanation of meta-ethnography has been included. “The different components of SA were analyzed using a meta-ethnographic framework. Metaethnography is a method with which to synthesize qualitative studies through an inductive analysis and integration of inter-study themes14.” Discussion of the findings starts with a bold assertion of „divergence from traditional biomedical conceptualizations of SA‟ (p.10). This statement needs empirical back-up. - The opening assertion in the discussion has been supported through a comparison tp the most recently published review of operational definitions of successful ageing. “The components of SA identified by the qualitative studies captured in the current review reflect a divergence from traditional biomedical conceptualizations of SA, highlighting the multidimensionality and psychosocial emphasis of SA. In contrast to operational definitions captured in the most recent Downloaded from http://bmjopen.bmj.com/ on March 5, 2016 - Published by group.bmj.com review SA which posit primarily biomedical models 7, attitudinal and engagement components were most frequently mentioned in the current review. Furthermore, external factors, such as finances and environment, which are absent in the majority of SA conceptualizations 7, were also frequently mentioned. The current review highlights the importance of psychosocial and external factors in SA definitions as well as emphasizes the multidimensional nature of SA. These results suggest that the incorporation of psychosocial and extrinsic components identified by laypersons into a multidimensional model of SA is a prudent means with which to augment biomedical conceptualisations of SA.” The Discussion presents some interesting perspectives on the scope of the concepts underlying SA. I recommend strongly that the number of discouraging comments concerning biomedical views on ageing is reduced, and where they are retained they should be based on evidence rather than prejudice. Why seek to publish in a biomedical journal and to antagonise the core readership? - This is a valuable point. The intent was not to antagonise the readership, but rather to highlight a potential shortcoming. We have rephrased and reframed these comments to emphasise the potential of lay perspectives to augment and improve biomedical conceptualisations of SA. For example: “These results suggest that the incorporation of psychosocial and extrinsic components identified by laypersons into a multidimensional model of SA is a prudent means with which to augment biomedical conceptualisations of SA.” Specific points 1. What is the definition of a qualitative study? Commonly, it means an open-ended or semi-openended question format. Is that your definition? - Our definition of qualitative research has been clarified as suggested. “Studies were considered to be qualitative if participants were asked open-ended or semi-open ended question(s).” 2. Please refer to evidence to support the claim that research on SA is dominated by quantitative studies (p.5). - References to the most recent quantitative and qualitative reviews of successful ageing have been provided. “The most recent reviews of quantitative definitions of SA 7 and qualitative perspectives of SA 8, reveal that there are more than twice as many studies examining operational definitions of SA as there are studies examining lay perspectives of SA. 3. The term „healthy ageing‟ is used in the Introduction. Please provide some indications of the difference between this term and SA. Downloaded from http://bmjopen.bmj.com/ on March 5, 2016 - Published by group.bmj.com - Terms for positive states of ageing generally do not have consensus definitions and are specified within the context of a given study. In the case of Hung. et al.‟s use of “healthy ageing”, they use the phrase as an “umbrella term” to capture several terms describing positive states of ageing, namely „successful aging‟, „active aging‟ „positive aging‟, „robust aging‟ and „aging well‟. The difference in usage of these terms has been clarified. “Further, whilst Hung, et al. 8 focused on the umbrella concept of “healthy ageing”, which they describe as capturing, “active ageing” “positive ageing”, “robust ageing”, “ageing well” as well as SA, the current review focusses specifically on SA. “ 4. The search strategy identified 5336 articles, not 10580. Please correct the flow diagram. - The flow diagram has been corrected to indicate the number of unique articles identified by the search strategy and to include the updated, i.e. up until March 22, 2013, search strategy. 5. Please consider a better term e.g. qualitative, rather than exploratory. A study with >1500 participants is not really exploratory. - In line with the clarification of “qualitative study” references to “exploratory” studies have been deleted. Reviewer: Tim Windsor Australian Research Council Future Fellow Flinders University of South Australia Australia No competing interests This manuscript reports a systematic review of qualitative research concerned with lay perspectives on successful ageing (SA). The question of what it means to age „successfully‟ is important from a social policy perspective, and the authors appear to have done a good job of identifying relevant qualitative studies, and emergent themes across the studies. Despite these strengths, there were a number of limitations that left me unconvinced as to whether the manuscript (at least in its current form) has the potential to make a significant contribution to the literature. First, there was no strong case made in the introduction as to why it is important to consider lay perspectives, and why these would be expected to be different to researcher-driven perspectives. - The importance of including qualitative studies in successful aging research has been clarified. “The aim of the study is to provide a comprehensive review of studies examining lay perspectives of SA, in order to augment the largely quantitatively dominated SA literature with insights from qualitative research. The most recent reviews of quantitative definitions of SA 7 and qualitative perspectives of SA 8, reveal that there are more than twice as many studies examining operational definitions of SA than there are studies examining lay perspectives of SA. However, in a study examining several different SA models, i.e. biomedical, psychosocial and lay models, the multidimensional lay model was found to be the strongest9. Through the acknowledgement of qualitative data, laypersons are given a voice to convey which aspects of SA they value 10. The incorporation of layperson perspectives expands and complements existing quantitative research, with the potential to improve both the quality and impact of research 11.” The rather broad claim is made that “through the acknowledgement of qualitative data, quantitative studies may be better informed, with increased practical relevance and impact”. How exactly do qualitative studies increase practical relevance and impact? Is there an appropriate citation to support this claim? Downloaded from http://bmjopen.bmj.com/ on March 5, 2016 - Published by group.bmj.com - As above, the importance of including qualitative studies has been clarified. The authors distinguish their review from that of Hung et al on the grounds that the Hung paper focuses on “healthy ageing”, whereas the current manuscript focuses on SA. It is not clear what this semantic distinction represents, particularly as the authors note that conceptions of successful ageing often have a biomedical focus. This is further complicated by the fact that “healthy ageing” was included as a synonym for “successful ageing” in the search strategy (p. 6). Bowling and Dieppe‟s (2005) review of researcher- and lay-definitions of successful ageing in BMJ should be cited, and how the current study makes an additional contribution clarified. - As noted in response to Reviewer 1, Hung, et al. specify that in the context of their study healthy ageing is used an umbrella term to capture successful aging as well as several other terms. A number of successful ageing synonyms were included in the search strategy, however it is later noted that studies discussing synonyms of SA, but without specific reference to SA were excluded from the review. This left me unsure as to why the synonyms were used - Synonyms for successful ageing were included in the search strategy to ensure that all successful ageing studies were captured. For example, a researcher may use a successful aging synonym in the keywords, which would be missed if the search strategy online included only successful aging; however, the study may ask participants “What is successful aging?”, which would meet inclusion criteria. Accordingly, we chose to err on the side of caution to ensure that every possible instance in which successful aging was specifically discussed was captured. . Some more detail on the foundations of the “meta-ethnographic framework” and how this is applied in identifying and organizing themes would be helpful for the reader unfamiliar with qualitative methods. - A further explanation of meta-ethnography has been included. “The different components of SA were analyzed using a meta-ethnographic framework. Metaethnography is a method with which to synthesize qualitative studies through an inductive analysis and integration of inter-study themes7” It was not clear to me what the term „items‟ (p. 8) referred to, and whether „item‟ is interchangeable with „theme‟. I would usually think of items as specific questions used in survey research. - As suggested, the term “item” was removed and replaced with component, for example: “All studies (n=24) included psychosocial components, 83% (20) included biomedical components, and 58% (14) included external components.” On p. 9 the authors indicate that physical functioning/disability was the most often mentioned of the constituent components of SA. This seems inconsistent with the abstract, and Figure 5. The results reported in the text of p.9 indicate that several themes (e.g., engagement) were identified by high percentages of studies (> 80%). However the maximum percentage value on the Y axis of Figure 5 is 20%. I was unable to work out how the text on p. 9 mapped onto the results of Figure 5. - Thank you for bringing this to our attention. The text has been changed to reflect the results presented in Figure 5. “A comparison of the percentage of respondents reporting each of the constituent components of SA Downloaded from http://bmjopen.bmj.com/ on March 5, 2016 - Published by group.bmj.com revealed engagement was mentioned most frequently, followed by perspective and self-awareness.” - Furthermore, the title of Figure five has been revised to indicate that the values on the Y axis represent the number of studies, not the percentage. “Figure 5: Frequency of studies reporting each of the SA components, by region” The main theme that is emphasized throughout the discussion is that biomedical models of SA are not sufficient, and that psychosocial components are also important to consider. This is an important point, but it seems to me that it is one already well-established in the SA literature (e.g., Bowling & Dieppe, 2005). Even Rowe and Kahn‟s (1997) model, despite its biomedical focus, acknowledges the importance of several psychosocial attributes including supportive social relationships and selfefficacy under the broader heading of „engagement‟. I felt that more was needed in the discussion to demonstrate how this study makes a unique contribution. - The focus of the discussion has been reframed to highlight the ability of lay perspectives of SA to augment, and potentially improve, biomedical models of SA. As Dr. Windsor highlights, this has been highlighted by previous studies, e.g. Bowling & Dieppe, 2005. The current makes a unique contributin to the literature by updating the most recent review of lay perspectives of ageing well (Hung, et. al) capturing nearly twice as many studies and conducting a much more in-depth analysis of the themes captured in their review. Through a meta-ethnographic analysis of the themes captured in the included studies the current review provides an unprecedented level of granularity, breaking down each component of SA within its broader themes. References Bowling, A., & Dieppe, P. (2005). What is successful ageing and who should define it? BMJ, 331, 1548-1551. Rowe, J. W., & Kahn, R. L. (1997). Successful aging. The Gerontologist, 37, 433-440 - Both references have been included. “The incorporation of layperson perspectives expands and complements existing quantitative research, with the potential to improve both the quality and impact of research11, increasing the validity and practical relevance of SA models 12. “ VERSION 2 – REVIEW REVIEWER REVIEW RETURNED GENERAL COMMENTS Tim Windsor ARC Future Fellow Flinders University Australia No competing interests 24-Apr-2013 The authors have done a good job of addressing most of the issues raised by me in the previous review. There are, however, a few remaining issues that I believe should be addressed before the manuscript is accepted for publication. 1) The new content included on pp. 5-6 that compares quantitative with qualitative studies in the area was not easy to follow. It was not clear to me what a „quantitative definition‟ is (a definition based on quantitative data? Use of quantitative data to provide evidence for a pre-defined model?), or what „operational definitions‟ refer to in this Downloaded from http://bmjopen.bmj.com/ on March 5, 2016 - Published by group.bmj.com context, and whether they are synomymous with quantitative approaches. Some clarification here would help in guiding the reader. 2) My point about the distinction between „healthy ageing‟ vs. „successful ageing‟ raised in the previous review was not clearly addressed. The authors now clarify that Hung et al. described “healthy ageing” as capturing active, positive, and robust ageing, and ageing well. In contrast, the current study is said to focus on SA. Yet, the search terms used to identify SA related papers included „healthy ageing‟ as well as all of the synonyms referred to above as being captured by Hung et al.‟s umbrella term. This suggests a strong degree of conceptual overlap between the two terms and leaves me no clearer as to why this semantic distinction is an important one to make. In the authors‟ response to the previous review they noted that the study extends Hung et al.‟s work by identifying more recent studies, a greater number of studies, and analysing the concepts around SA in greater depth via the metaethnographic analysis. To me, these are more compelling issues to refer to in arguing for what the study adds to the literature than focusing on a conceptual distinction between healthy ageing and SA that (for me at least) is difficult to follow. 3) Pp. 15-16: “proponents of strictly biomedical models suggest that psychosocial components should not be included in models of SA” This statement seems rather strong. As I noted in the previous review, Rowe and Kahn (cited in the manuscript as a prime example of the biomedical approach) acknowledge the importance of some psychosocial components in the context of active engagement. If some proponents of strict biomedical models do make the explicit claim that psychosocial components should not be included in SA models, then relevant citations should be provided. Otherwise this point should be re-framed to reflect the different emphasis of the biomedical approach, rather than implying that biomedical approaches actively eschew psychosocial perspectives. 4) Reference 7 appears to be a duplicate of reference 1. VERSION 2 – AUTHOR RESPONSE 1) The new content included on pp. 5-6 that compares quantitative with qualitative studies in the area was not easy to follow. It was not clear to me what a „quantitative definition‟ is (a definition based on quantitative data? Use of quantitative data to provide evidence for a pre-defined model?), or what „operational definitions‟ refer to in this context, and whether they are synomymous with quantitative approaches. Some clarification here would help in guiding the reader. - The quantitative studies to which we refer are ones in which successfully ageing has been conceptualised by researchers and quantified, namely via operational definitions. This has been clarified to acknowledge the contrast between researcher-driven conceptualisation and lay perspectives of successful ageing. “The aim of the study is to provide a comprehensive review of studies examining lay perspectives of SA, in order to augment the many researcher-driven conceptualisations of SA with insights from qualitative research. The most recent reviews of operational definitions of SA1 and qualitative perspectives of SA7, reveal that there are more than twice as many studies positing operational definitions of SA as there are studies examining lay perspectives of SA. However, a study examining several different SA models, i.e. biomedical, psychosocial and lay models, found the multidimensional lay model to be the strongest8. Through qualitative studies laypersons are given a platform to voice Downloaded from http://bmjopen.bmj.com/ on March 5, 2016 - Published by group.bmj.com their opinions and perspectives on research topics9. Therefore, the incorporation of layperson perspectives expands and complements researcher-driven conceptualisations of SA, with the potential to improve both the quality and impact of research10, increasing the validity and practical relevance of SA models 11 .” 2) My point about the distinction between „healthy ageing‟ vs. „successful ageing‟ raised in the previous review was not clearly addressed. The authors now clarify that Hung et al. described “healthy ageing” as capturing active, positive, and robust ageing, and ageing well. In contrast, the current study is said to focus on SA. Yet, the search terms used to identify SA related papers included „healthy ageing‟ as well as all of the synonyms referred to above as being captured by Hung et al.‟s umbrella term. This suggests a strong degree of conceptual overlap between the two terms and leaves me no clearer as to why this semantic distinction is an important one to make. In the authors‟ response to the previous review they noted that the study extends Hung et al.‟s work by identifying more recent studies, a greater number of studies, and analysing the concepts around SA in greater depth via the meta-ethnographic analysis. To me, these are more compelling issues to refer to in arguing for what the study adds to the literature than focusing on a conceptual distinction between healthy ageing and SA that (for me at least) is difficult to follow. - Clarification as to why all of the successful ageing related terms were included in the search strategy have been included. “This process was repeated across the six databases using the seven SA related phrases. The SA related terms were included to capture studies that, for example, listed “ageing well” in their keywords, but asked “What is your definition of successful ageing?” in interviews with participants. If only “successful ageing” had been used in the search strategy it would have been missed. Therefore, in an effort to capture every SA instance the seven SA related terms were used in the search strategy. “ The acknowledgement of the update and expansion of Hung, et al.s review has been further noted: “The current study updates and expands a previous review by Hung, et al. {hung}, collecting, synthesising, and proving a comprehensive examination of layperson conceptualisations of SA.” 3) Pp. 15-16: “proponents of strictly biomedical models suggest that psychosocial components should not be included in models of SA” This statement seems rather strong. As I noted in the previous review, Rowe and Kahn (cited in the manuscript as a prime example of the biomedical approach) acknowledge the importance of some psychosocial components in the context of active engagement. If some proponents of strict biomedical models do make the explicit claim that psychosocial components should not be included in SA models, then relevant citations should be provided. Otherwise this point should be re-framed to reflect the different emphasis of the biomedical approach, rather than implying that biomedical approaches actively eschew psychosocial perspectives. - This section has been reframed to emphasise the ability of psychosocial components to augment and improve biomedical approached. “Many of the components identified by layperson as being important (e.g. engagement, selfawareness, perspective, etc.) present the opportunity for the implementation of specific interventions for modifiable behaviors. For example, aiding individuals in, decreasing depressive symptomology, social engagement, invoking coping and resilience training, could augment and compliment physical remediation strategies, as identified by biomedical models, in the pursuit of SA. Therefore, it is prudent to augment the scope of biomedical models to areas of the lived life that have not been covered by traditional models of SA.” 4) Reference 7 appears to be a duplicate of reference 1. The duplicate reference has been deleted. Downloaded from http://bmjopen.bmj.com/ on March 5, 2016 - Published by group.bmj.com Lay perspectives of successful ageing: a systematic review and meta-ethnography Theodore D Cosco, A Matthew Prina, Jaime Perales, Blossom C M Stephan and Carol Brayne BMJ Open 2013 3: doi: 10.1136/bmjopen-2013-002710 Updated information and services can be found at: http://bmjopen.bmj.com/content/3/6/e002710 These include: References This article cites 46 articles, 11 of which you can access for free at: http://bmjopen.bmj.com/content/3/6/e002710#BIBL Open Access This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. 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