Ambulatory Reflux Monitoring (pH - Impedance) Sierra Scientific Instruments, Inc. Applications Lab Los Angeles, CA 866.641.8492 Last,First Patient: Last,First 123456 Gender: DOB / Age: Height: Weight: Indications: Female 03-20-1975 5 ft 4 in 135 lb GERD Physician: Operator: Referring Physician: Physician Operator Referring Physician Study Date: 03/14/2008 pH Analysis Thresholds Threshold, pH Channel 1 4,0 Sierra Scientific Instruments Inc. Los Angeles, CA 1 of 1 Toll-free: 866-641-8492 www.sierrainst.com Ambulatory Reflux Monitoring (pH - Impedance) Sierra Scientific Instruments, Inc. Applications Lab Los Angeles, CA 866.641.8492 Last,First Acid Reflux Analysis Total Total duration (HH:MM) Time spent in reflux (HH:MM) Number of refluxes % Time spent in reflux Number of long refluxes Longest reflux (HH:MM) Upright Total duration (HH:MM) Time spent in reflux (HH:MM) Number of refluxes % Time spent in reflux Number of long refluxes Longest reflux (HH:MM) Supine Total duration (HH:MM) Time spent in reflux (HH:MM) Number of refluxes % Time spent in reflux Number of long refluxes Longest reflux (HH:MM) 13:20 00:08 14 1,0 0 00:01 07:12 00:08 14 1,9 0 00:01 06:08 00:00 0 0,0 0 N/A DeMeester Score Normal ≤ 14.72 (95th percentile) Channel 1 3,8 DeMeester Scoring Components Number of refluxes Number of long refluxes Longest reflux (min) Time below acid thresh. (%) - Total Time below acid thresh. (%) - Upright Time below acid thresh. (%) - Supine Total score Channel 1 25,2 0,0 00:01 1,0 1,9 0,0 3,8 Reflux Episode Activity* Total Acid reflux Weakly acidic reflux Non-acid reflux All reflux Upright Acid reflux Weakly acidic reflux Non-acid reflux All reflux Supine Acid reflux Weakly acidic reflux Non-acid reflux All reflux * Episodes/24 hr. ** 95th percentile Bolus Exposure Time* 5,0 cm above LES Total 0,3 Upright 0,5 Supine 0,0 *% time refluxate in contact with impedance sensors Channel 1 Symptom Correlation to Reflux Number of occurrences Acid related Weakly acidic related Non-acid related All reflux related Unrelated Heartburn 3 1 0 0 1 2 Chest Pain 5 0 1 0 1 4 Reflux Symptom Index Acid reflux Weakly acidic Reflux Non-acid reflux All reflux Heartburn 33,3 0,0 0,0 33,3 Chest Pain 0,0 20,0 0,0 20,0 Reflux Symptom Association Heartburn Chest Pain Probability* Acid reflux 98,9 99,9 Weakly acidic reflux 0,0 99,1 Non-acid reflux 0,0 0,0 All reflux 97,5 100,0 * Probability that symptom and reflux are not associated solely by chance, (>95% is significant) Channel 1 Normal** 20 5 0 25 55 26 1 73 Proximal Esophageal Reflux* Total Acid Weakly acidic Non-acid * Percent of distal episodes 71,4 81,8 33,3 N/A 20 5 0 25 0 0 0 0 Procedure example1 Interpretation / Findings example2 Sierra Scientific Instruments Inc. Los Angeles, CA 2 of 2 Toll-free: 866-641-8492 www.sierrainst.com Ambulatory Reflux Monitoring (pH - Impedance) Sierra Scientific Instruments, Inc. Applications Lab Los Angeles, CA 866.641.8492 Last,First Example Diary Event Meal Med Chest Pain Heartburn Chest Pain Heartburn Med Supine Chest Pain Chest Pain Meal Chest Pain Heartburn Day 1 1 1 1 1 1 1 1 1 1 1 1 1 Begin 7:38AM 8:25AM 8:47AM 9:00AM 9:08AM 9:24AM 10:25AM 10:46AM 11:28AM 5:03PM 5:30PM 7:24PM 8:14PM End 7:50AM Duration 00:12 4:54PM 06:08 5:46PM 00:16 Note Sierra Scientific Instruments Inc. Los Angeles, CA 3 of 3 Toll-free: 866-641-8492 www.sierrainst.com Ambulatory Reflux Monitoring (pH - Impedance) Sierra Scientific Instruments, Inc. Applications Lab Los Angeles, CA 866.641.8492 Last,First Sierra Scientific Instruments Inc. Los Angeles, CA 4 of 4 Toll-free: 866-641-8492 www.sierrainst.com Ambulatory Reflux Monitoring (pH - Impedance) Sierra Scientific Instruments, Inc. Applications Lab Los Angeles, CA 866.641.8492 Last,First Sierra Scientific Instruments Inc. Los Angeles, CA 5 of 5 Toll-free: 866-641-8492 www.sierrainst.com