NanoBioAnalytics-Region Münster Concept and Background HORIZON 2020 EUROPEAN UNION FUNDING FOR RESEARCH & INNOVATION Our interest Analysis of cell - material interactions Fromherz, Munich Strong analytical location Electron Microscopy (1970) (20) Mass Spectrometry (1980) Ions (SIMS) (15) Laser (MALDI) (6) Atomic Force Microscopy (1990) (40) Ion Sputtering (2000) (2) Competitive biomedical research Max-Planck Institute fo Molecular Biomedicine Research Topics • Prof. Schöler •Stem cell differentiation •Prof. Adam •Blood vessel development •Prof. Vestweber •Immune response in blood cells Large University Clinic Clinic area • 70 clinics and institutes • 160 Professors • 7000 Employees • 400,000 Patients per year • Strong focus on research Research area • Five main research areas • Inflammation and transplantation • Cardiovascular medicine • Tumor medicine • Neuro medicine • Reproduction and Regeneration medicine Companies 30 Companies with more than 1000 employees Nano Analytics Bio Medicine Goal Develop Münster into a leading Nano-BioAnalytics location in Europa Infrastructure Science Park Münster NBZ MPI Clinics IONTOF T-Hof CeNTech Geo Pharmaceutics Chemistry Physics MEET Municipal ivestments in infrastructure • Year Investment City of Münster* BioZ 2002 4,6 Mio. Euro 4,6 Mio. Euro CeNTech I 2003 8,7 Mio. Euro 3 Mio. Euro CeNTech II 2011 7,5 Mio. Euro House builder function NBZ 2011 16,2 Mio. Euro 3 Mio. Euro oder städtische Gesellschaften wie Wirtschaftsförderung Münster GmbH, Technologieförderung Münster GmbH oder CeNTech GmbH Strategic Networking Co-ordinated network Science Transfer Economy Technologiepark Universities Town of Münster Investors Other partners Bio.NRW young Start-Ups Founder of companies Research centers IHK Münster CeNTech Kompetenzzentrum Nanoanalytik Established companies Status 2000 MPI MPI CeNTech EIMI City UNI Status 2014 UNI FH EIMI MPI UKM Companies CeNTech City Communication of Science in Münster NanoBioAnalytik in Medtech and Pharma Medical Prevention Westfalian Peace 1648 – Dialogue for Peace Strategic partnership in NRW Bio BIO.NRW Strategic partnership in NRW Nano Cluster Nano/Micro+ Materials.NRW Strategic Partners at national level in the field of Bio Strategic Partners at European level in the field of NanoBio Uni Lund MIC Copenhagen Mesa+ Twente Tyndall Cork INSAT Newcastle Bioanalytik, Uni Münster, Centech Uni Mainz, Uni Saarland, Uni Kaiserslautern NanoBioNet, IBMT CEA, CNRS, INSERM EPFL Lausanne, FSRM PCB Barcelona JRC Ispra Demokritos Athens, FORTH Uni Tel Aviv Strategic partnership at European level Strategic Projects in Nanosafety Technologies Mass Spectrometry Electron Microscopy Holographie AFM XPS und LEIS Optical Profilometry AFM Holography Flow and Scanning Cytometry TOF SIMS REM/SEM Test systems Lung and particle research with industrial partners Analysis of dynamic processes in human cell systems by optical methods Development and validation of in vitro systems as replacement for animal testing. Alveolarmakrophage P. Boisseau Twente July 6, 2005 2 3 Applications Food and Feed Pharmaceuticals Cosmetics Environment Occupational safety Cells and tissues Consumer products Alveolarmakrophage QM-based nano-characterization Industrial Customers Environment Food Cosmetics Pharma www.ncl-muenster.de EU-NCL concept of operation Metrology Institutes Sources of materials Regulatory bodies EU-NCL Analytical report for pre-clinical tests Academia RTO Prevention Characterization cascade SMEs Pharma Diagnostics Therapeutics Physical and chemical characterization Regenerative medicine In vitro assays In vivo assays European landscape for EU-NCL European Partners • CEA Grenoble and Saclay (France) • Bioanalytikmuenster (Germany) • JRC-IHCP (Italy) • EMPA (Switzerland) • SINTEF (Norway) • CRANN (Ireland) • Uni Liverpool (UK) US Partner • NCI-NCL JRC-IHCP EU-NCL Münster 30