Nursing Education Calculating Drug Dosage 1. Ba s ic Ra tio & P ro p o rtio n Ca lc u la tio n Wh e n th e d o s e o n h a n d is n o t th e s a m e a s th e d e s ire d p e r o rde re d d o s e Dose on hand Quantity on hand === Desired dose (Drug order) Quantity desired (x ) = For example: 500 mg is ordered. It is available in 250 mg capsule (s). Solve X to get the number of capsule(s) to give S te p 1 Dose on hand (250mg) Quantity on hand (1 capsule) === Desired dose (500mg) = Quantity desired (x capsule(s)) S te p 2 250 mg 500mg === 1 capsule = x capsule(s) Resulting in an equation: 250mg x X capsule(s) = 1 capsule x 500mg S te p 3 === X capsule(s) = 1 capsule x 500 mg 250 mg = S te p 4 An s we r: JW 9/10, JW 2/13 2 Capsules 1 500 250 Nursing Education Calculating Drug Dosage Dose on hand Quantity on hand Desired dose (Drug order) Quantity desired (x ) === = For example: 5000 units are ordered. It is available in a vial containing 10,000 units/mL. Solve X to get the number of mL(s) to give S te p 1 Dose on hand (10, 000 Units) Quantity on hand (1 mL) === Desired dose (5000 units) = Quantity desired (x mL) S te p 2 10,000 Units 1 mL 5000 Units === = x mL Resulting in an equation: 10,000 Units x X capsule(s) = 1 mL x 5000 Units S te p 3 === X capsule(s) = 1 mL x 5000 Units = 10, 000 Units 5000 10,000 S te p 4 An s we r: JW 9/10, JW 2/13 0.5 mL 2 Nursing Education Calculating Drug Dosage 2. Ca lc u la tin g Me d ic a tio n in S olu tion Volume to be Administered = Dose Ordered Available concentration in 1 mL For example: 8 mg is ordered. It is available as 10mg/mL S te p 1 Volume to be Administered = Dose Ordered (8 mg) Available concentration in 1 mL (10 mg/mL) S te p 2 8 10 mL S te p 3 An s we r: 0.8 mL *** If concentration is not available for 1 mL, you must calculate the concentration for 1 mL by taking the total dose and dividing it by the total volume to calculate dose per mL For example: Calculate the mg/mL concentration for 50 mg of a drug in 100 mL S te p 1 50 100 mL S te p 2 An s we r: JW 9/10, JW 2/13 0.5 mg/mL 3 Nursing Education Calculating Drug Dosage 3. Ca lc u la tin g IV Flow Ra te s For example: 1000 mL IV solution ordered to infuse over 8 hours S te p 1 1000 mL 8 hr === = (x mL) 1 hr Resulting in an equation: 8 hr x X mL = 1000 mL x 1 hr S te p 2 X mL 1000 mL x 1 hr 8 hr = S te p 3 An s we r: JW 9/10, JW 2/13 125 ml/hr 4 Nursing Education Calculating Drug Dosage 4. Ca lc u la tin g a Drip Ra te u s in g a n IV Tu b in g Drip Fa c to r Th e Drip Ra te is th e n u m b e r o f d ro p s (g tts ) p e r m in to b e in fu s e d (g tts /m in ) Th e Drip Fa c to r o f th e IV tu b in g is d e te rm in e d b y th e m a n u fa c tu re r. Th is in fo rm a tio n c a n b e fo u n d o n th e IV tu b in g p a c ka g in g . Th e Drip Fa c to r is th e n u m b e r o f d ro p s th a t e q u a l 1 m L o f s o lu tio n . IV Drip Rate (gtts/min) Volume to be Infused (mL) x Drip Factor of tubing (gtts/mL) Time (in min) to be infused = For example: 1000 mL of NS ordered to be administered over 8 hours. The IV tubing drip factor is 10 gtts/mL. S te p 1 : Co ve rt Ho u rs to Min u te s The IV infusion is ordered to be administered over 8 hours There are 60 minutes in 1 hour 8 hours x 60 minutes = 480 minutes S te p 2 IV Drip Rate (gtts/min) = 1000 mL x 10 (gtts/mL) 480 min = 10000 gtts 480 min S te p 3 IV Drip Rate (gtts/min) S te p 4 An s we r: 20.83 gtts/min Round to nearest whole number = 21 gtts/min JW 9/10, JW 2/13 5