THE SAN DIEGO CHEMIST American Chemical Society Volume 25, Number 1 San Diego Section January 2013 The Chemistry of a Successful Biotech Company: The Excaliard Story Nicholas M. Dean, Ph.D. Founder and Chief Scientific Officer Excaliard Pharmaceuticals, Inc. 2141 Palomar Airport Road, Carlsbad, CA DATE: Thursday, January 24, 2013 TIME: 6:00 PM Social Hour, Light Dinner 7:00 PM Lecture PLACE: Dart NeuroScience Wateridge Campus 10420 Wateridge Circle San Diego, CA 92121 RESERVATIONS: By Monday, January 21, 2013 http://sandiegoacsnmdean2013.eventbrite.com ABOUT THE SPEAKER: Prior to founding Excaliard in the spring of 2006, Dr. Dean served for four years as Vice President of Functional Genomics and Oncology at Isis Pharmaceuticals where he also served as Managing Director, Isis Singapore. Dr. Dean originally joined Isis Pharmaceuticals in 1991 and served in various roles in the molecular pharmacology department until 2000 at which time he became Executive Director and Vice President, Functional Genomics for Isis Pharmaceuticals. Dr. Dean received his Ph.D. in Pharmacology from the Welsh National School of Medicine. He then spent time conducting research at the National Cancer Institute and the University of Hawaii before joining Isis Pharmaceuticals. Dr Dean has authored more than 110 scientific papers and more than 50 issued patents. Sponsor: CHAIR NOTES Dear ACS members: Let me start by saying thank you for electing me to be your chair for 2013. I am honored by the position and look forward to an exciting year ahead. It’s important to note now that I will have tough act to follow. Fred Heineken did an amazing job in 2012 and I am humbled to take the reins. We will miss him tremendously. As many of you know, our previous chair, Fred Heineken, recently passed away on November 19th with family by his side. We are deeply saddened by such an unexpected loss. Fred was an integral part of ACS and we owe him an incredible amount. During the last month, thanks to Fred’s son Chris Heineken and his friends we have learned a great deal about the quiet bright blue-eyed man who led our Section this past year. It is my pleasure to share a few details with you. Fred was born in Illinois in 1939. He was very active in Boy Scouts which led to becoming an Eagle Scout. After high school, he went on to receive a B.S. in Chemical Engineering from Northwestern and his Ph.D. from the University of Minnesota. Fred’s first job after college was at Monsanto in Colorado. He later joined the National Science Foundation in Washington, D.C., where he stayed for 25 years before retirement. During his career, Fred made countless contributions to the field of metabolic engineering and microbiology. He was a Fellow of the American Institute of Chemical Engineers, received awards for distinguished service at the National Science Foundation and held several leadership posts with the American Chemical Society. He had been a member of ACS since 1968. After retirement, Fred moved to San Diego to be close to his son Chris Heineken, daughter-in-law Katy Heineken, and three granddaughters Sarah, Emma, and Megan. He was an incredible father and grandfather, known by the family and friends for his open arms which were always there for warm hugs. We will miss Fred dearly in the future and my thoughts and prayers are with his family during this difficult time. It is at this time that I must thank those executive board members that I am lucky to be working with in 2013. The executive team is made up of Mark Tichenor (chair-elect), Bill Tolley (secretary), and Bill Szabo (treasurer). In addition I must thank all of our committee chairs, councilors, alternate councilors, and members-at-large. It’s quite a team and I know it will allow for a fantastic year full of fun and valuable events. Our next board meeting will take place on January 3rd at Pharmatek. I invite you to come to volunteer, meet others, or tell us what you would like to see in 2013. Please remember, you are all paying members to ACS and we would like to make our events as valuable to you as possible. Your opinion counts so please let us know what you think! The theme of next year is Technology Born in San Diego. I am so proud to live in San Diego and be a part of the discoveries and developments happening every day in our community. It’s important for us to learn and support these innovations. Additionally by learning from the successes and challenges of others, we will begin to understand about what it takes to make ideas a reality. With that being said we have some great events planned for the coming months. Firstly, Nicholas Dean will be speaking on January 24th. He is the founder of Excaliard and will be talking about their development of antisense oligonucleotide EXC 001 for the treatment of skin fibrosis. In 2011, Excaliard was acquired by Pfizer and EXC 001 recently had positive results from some phase two clinical studies. Please see the newsletter for additional information! Additionally, in February, Martin Rowbottom from Ambit Biosciences will be speaking about the discovery of CEP-32496, a Second-Generation BRAFV600E Kinase Inhibitor for the treatment of cancer. In addition to these events please look forward to our yearly favorites. These include Academics to Industry, EarthFair, Mad Science, Seniors Breakfasts, Education Awards Banquet, Family Picnic, 50-/60-Year Member Luncheon, MedChem Symposium, ChemExpo, Distinguished Scientist Award Banquet, CATE Lectures, Holiday Party and the many events from the Government Affairs, Law, Professional Development, the Women Chemists Committee and the Younger Chemists Committees. Finally, on behalf of the Executive Board of the San Diego Section of the ACS, best wishes to you and yours for a Joyful Holiday Season and for a Happy and Healthy New Year! Erica Campbell-Conroy 2013 Chair American Chemical Society – San Diego Section E-mail: ericalconroy529@gmail.com Web: www.sandiegoacs.org THE SAN DIEGO CHEMIST, the official newsletter of the San Diego Section of the American Chemical Society, is published on a monthly basis and can be viewed at http://www.sandiegoacs.org/newsletter/. All contents are published at the discretion of the Section's Executive Committee. Events of interest to chemistry professionals in the community may be included in the events calendar as space permits and are subject to editing for brevity. Advertisements and announcements from the chemistry community are accepted at published rates. The deadline for items submitted is the 14th of the month prior to publication. Further information regarding events is available on the Section web page at http://www.sandiegoacs.org/. Advertisers: Current ad prices are: Large (4.5"x4.75") $200; Small (2"x3" or 4.5"x1.5") $65. All measurements are wide x tall. Please send your jpg to Renate Valois at renate@sandiegoacs.org. Make checks payable to American Chemical Society and mail to Bill Szabo, Treasurer 3950 Mahaila Avenue, B-36 San Diego, CA 92122 SECTION E-MAIL LISTSERVER! Get up-to-the-minute reminders of local events and develop dialogs with your fellow members! To subscribe to our moderated listserver: 1) Type the following URL in your browser and go to this site: http://lists.ucsd.edu/mailman/listinfo/sandiego-chemist-l 2) Follow the instructions to insert your name, email address, preferences, etc., and enter SUBSCRIBE. 3) When you receive a message from the postman, reply to confirm that you wish to be added to the list, otherwise it will not take effect. 4) You will receive reminders approx. 5-7 days prior to upcoming events and messages of general interest to members. 5) To send questions/topics for discussion, or informational items to the listserver members, send the message to sandiego-chemist- l@ucsd.edu. 6) If the moderator approves the post, it will be sent to the members. NOTE: That is the letter "l", not the number "one" following the word "chemist". Executive Board Meeting Dates 2013 6 PM – 8 PM Thursday Thursday Thursday Thursday Thursday Thursday Tuesday Thursday Thursday Thursday Thursday January February March April May June July August September October November 3 7 7 4 2 6 9 1 5 3 7 Meetings will be held at Pharmatek Laboratories, Inc. 7330 Carroll Road, San Diego, CA 92121 http://www.pharmatek.com/ OBITUARY Frederick G. Heineken, 73, 2012 Chair of the San Diego ACS – San Diego Section and recently retired Program Director of the NSF Biochemical Engineering/Biotechnology Program, died on Nov. 19 following cardiac complications. Born in Chicago, Illinois, Heineken earned a B.S. from Northwestern University in 1962 and a Ph.D. from the University of Minnesota in 1966 in chemical engineering. Until 1971 he was a senior biochemical research engineer at Monsanto, after which he pursued postdoctoral work at the Webb-Waring Lung Institute at the University of Colorado, Denver. From 1976 to 1984 he was department head and senior project engineer for COBE Laboratories in Lakewood, Colorado. He joined NSF in 1985 where he remained until his retirement in 2009. He was awarded the NSF Meritorious Service Award in 2005. Heineken was a Fellow of the ACS, class of 2010, and received the James M. Van Lanen Award for Distinguished Service in the Biochemical Technology Division of ACS in 1996. He was also a member of AIChE, AAAS and the American Society for Artificial Internal Organs. Heineken made pioneering discoveries in tissue engineering, metabolic engineering, the modeling of biochemical reaction networks and the use of recombinant DNA to make valuable products. Through his post at NSF, he formed interagency coalitions in metabolic engineering to provide funding for this nascent field. He chaired the Multi-Agency Tissue Engineering Science (MAPES) Working Group, 2000-2008. His influence was worldwide. He was a member of the Scientific Advisory Committee for International Science and Technology Center in Moscow 1995-1996 and served as an Embassy Science Fellow in Berlin in 2005. He served the ACS as a member of over a dozen national committees and a Councilor for seventeen years in the Biochemical Technology Division. From 2005-2010 he chaired the Division Councilor’s Caucus. He is survived by his son, Christopher, daughter-­‐in-­‐law Katy and three granddaughters. Consider Sponsorship of the ACS San Diego Section! The San Diego Section of the ACS is looking for organizations that are committed to advancing science and education in the greater San Diego area by providing financial support. There are several ways to get involved and each one comes with its own benefits and privileges. Please contact Bill Szabo for further information: Bill Szabo Chair, Fundraising Committee Tel/Fax: 858-550-0306 bszabo1@san.rr.com The San Diego Section of the American Chemical Society would like to thank our Corporate Sponsors Silver Level Sponsor Bronze Level Sponsors ************************************************************************************* ACS-Hach Programs http://portal.acs.org/portal/acs/corg/content?_nfpb=true&_pageLabel=PP_SUPERARTICLE&node_id=491&use_sec=fal se&sec_url_var=region1&__uuid=060ed90e-3bc3-44ed-9ba6-5b01dffd42e0 The next application period will be February 1 – April 1, 2013 ACS-Hach Second Career Teacher Scholarship The ACS-Hach Second Career Teacher Scholarship is awarded to professionals in the chemistry field pursuing a Masters degree in education or becoming certified as a chemistry/science teacher. Scholarship recipients receive either up to $6,000 for full-time study or up to $3,000 for part-time study. Recipients who meet the award criteria are eligible to renew the award annually up to three years. The scholarship can be applied to tuition, books, room and board, and other education-related expenses. ACS-Hach High School Chemistry Grant Since 2008, over 400 high school chemistry teachers received ACS-Hach High School Chemistry Grants to support ideas that enhance classroom learning, foster student development, and reveal the wonders of chemistry. ACS-Hach Land Grant Scholarship The ACS-Hach Land Grant Scholarship is awarded to undergraduate chemistry majors who attend one of our 72 partner institutions and express an interest in teaching high school chemistry. Award Amount: $6,000 for full-time study Application Period: Contact participating universities directly for application details. For questions and additional information, contact us at (800) 227-5558 ext. 8178 or hach@acs.org ACS Grants ACS offers grants to support the advancement of the chemical sciences through research, education, and community projects. Learn how you can benefit. - Petroleum Research Fund - TEVA Pharmaceuticals Scholars Grants - Herman Frasch Foundation Grants - Irving S. Sigal Postdoctoral Fellowship - Green Chemistry - Public Policy Fellowships - ACS Community Recognition Grants - Corporate Associates Seed Grants - Corporation Associates Local Section Grants - ACS High School ChemClub Community Activities Grants An Evening with William F. Carroll, Jr., Ph.D. The Chemistry Enterprise: Do We Have a Future, or What? November 15, 2012 Organizers Mark Tichenor, Gulin Erdogan, Erica Campbell-Conroy Whitney Fies, Gulin Erdogan, Isabelle Lerario Bill Carroll and John Palmer Jason McCartney and Dennis Hurley Erica Campbell-Conroy introduces Bill Carroll Bill Bruinsma and Rita Lim enjoy the Greek cuisine Will Harvery looks over the 2011 ChemLuminary Award poster A well-decorated John Schindler Bill Carroll makes a point Crowd listens attentively Tom Beattie, Don Victor, Bill Carroll at Doyle Elementary Tom and Mary Ann Beattie share a laugh Photo credits: Bill Szabo Year-end Wrap-up and Holiday Party The San Diego Section of the ACS held its annual Holiday Party on Thursday, December 6th, at Miramar-Chin’s Seafood and Grill. Mark Tichenor, the 2013 Chair-Elect, presented a review of activities this year, and Erica Campbell-Conroy, 2013 Chair, talked about her plans for next year. We hope you all enjoyed the event! Mark Tichenor Chair-Elect 2013 Tom Beattie paying tribute to Fred Heineken Erica Campbell-Conroy, Chair 2013 Mark Tichenor rewiews activities of 2012 Erica Campbell-Conroy outlines activities for 2013 Ben Pratt, Mark Tichenor enjoying their beer Erica Campbell-Conroy, Ryan Clark Janet and Bill Tolley Ben Pratt, Tom Beattie, Ken Poggenburg John Schindler, Erica CampbellConroy, Paul and Karin Bruinsma, Julann Miller Ken Poggenburg, Will Harvey Masha Sergeeva, Will Harvery, Julann Miller John and Renate Valois, John Schindler, Mary Ann Beattie Will Harvey, Julann Miller Bill Szabo, Ken Poggenburg John Schindler, James Caldwell Will Harvey Robert and Suzanne Leif Paul and Karin Bruinsma Tom Beattie, Masha Sergeeva Rodney Harris, Surya De Matthew Wiley, Nate Luman, SuzAnn Hertzler David Wallace John and Renate Valois Photo credits: Jim Shih and Bill Szabo Pacifichem 2015: Get Ready for Call for Symposium Proposals Pacifichem 2015 (Honolulu, Hawaii, USA December 15 - 20, 2015) may seem a long way away, but the Call for Symposium Proposals is right around the corner: January 1 – April 1, 2013. ACS Technical Division members are encouraged to work with their division’s program committee to submit cutting-edge symposium proposals relevant to the Pacifichem 2015 Topic Areas. For more information on submitting symposium proposals to Pacifichem 2015, see the Pacifichem 2015 web site: www.pacifichem.org. Click the Technical Program tab for Topic Areas and Symposium Proposal Submissions. The San Diego Section of the American Chemical Society Welcomes Its New Members Attention Companies! Do you hire student workers? If you have open positions in chemistry and biochemistry that would be of interest to college students, such as summer internship opportunities, here is a list of contacts you’ll want to keep handy. The people listed below are the faculty advisors of the ACS Student Affiliate groups for all chemistry programs in San Diego County. These professors can get the word out to all chemistry and biochemistry majors at their schools about jobs, career fairs, open houses, etc. California State University, San Marcos Jacqueline Trischman trischma@csusm.edu 760-750-4206 Fax 760-750-3199 Point Loma Nazarene University Sara Choung SaraChoung@PointLoma.edu 619-849-2627 Fax 619-849-3452 San Diego Mesa College Dwayne Gergens dgergens@sdccd.edu 619-388-2609 Fax 619-388-2677 San Diego Miramar College Linda Woods lwoods@sdccd.edu 619-388-7434 Fax 619-388-7929 San Diego State University (SDSU) Mikael Bergdahl bergdahl@sciences.sdsu.edu 619-594-5865 Fax 619-594-4634 Southwestern College, Chula Vista David Brown dbrown@swccd.edu 619-421-6700x5664 Fax 619-482-6503 University of California, San Diego (UCSD) Judy Kim judyk@ucsd.edu 858-534-8080 Gourisankar Ghosh gghosh@ucsd.edu 858-822-0469 University of San Diego (USD) Debbie Tahmassebi debbiet@sandiego.edu 619-260-7454 Fax 619-260-2211 Monthly Historical Events In Chemistry By Leopold May The Catholic University of America http://faculty.cua.edu/may/ChemistryCalendar.htm Sarah Asper Joe Binder Jeffrey Buenaflor Daniel Burke Cole Carter Pang Chen Wu Ching Chou Melissa Clark Kristen Darrell Brian Doyle Andrew Drake Katharine Duncan Xiaorui Fan Mike Fernandez Olivia Graeve Will Gutekunst Sophia Hirakis Sandy Ho Rhoda Hughes Tracey Huynh Yu-Jer Hwang Lawrence Jones Rameshwar Kadam Kirsten Kale Andrea King Than Kyaw Victoria Lang Jolene Lau Qiuhan Li Emiliano Llave John Marohn Saif Namiq Michelle Nguyen Quynh-Mai Nguyen Jenny Nhan Joshua Park Maxim Ratnikov Rhianna Rodea Kevin Rynearson Alex Schammel Cynthe Sims Motohiro Takahashi Khanh Tan Ryan Van De Water Robert Yeh Leon Zhou ACS Webinars™ Featured Events – January 2013 A Toast to the Chemistry of Noble Grapes Thursday, January 10, 2013 Joy of Science Channel: Food Chemistry Series Come learn about the chemistry that makes the noble grapes and the wine they make so great! Great grapes make great wine. Traditionally, only six types of grape have earned the right to be called Noble and to have been used to make the finest wines. Delve with us, into the compounds of reds, whites and why some chemistry is best served chilled. Speaker: Susan Ebeler, University of California, Davis. Alternative Careers: From the Lab Bench to the Kitchen Bench Thursday, January 17, 2013 Careers Channel Join Bill Courtney as he shares how he used his knowledge of chemistry to start his own restaurant! What do the lab and the kitchen have in common? It’s where you mix compounds, apply heat and ponder the possibilities. Whether working through a formula or flipping through a cookbook, creativity starts at the bench. Ignorance: Why Science Should Not Start with a Hypothesis Thursday, January 24, 2013 Joy of Science Channel: Extreme Chemistry Series Join Stuart Firestein as he explains how approaching research in a new way can lead to amazing results. Knowledge is a big subject. Ignorance is a bigger one. The most important outcome of scientific investigation is ignorance – newer, better ignorance. As many papers and books are produced each year in scientific journals, even more ignorance is created – It’s the nature of a successful experiment! Gender Bending Chemicals: Impacts of Endocrine Disrupting Chemicals Thursday, January 31, 2013 Joy of Science Channel: Extreme Chemistry Series Join Dr. Charles Tyler as he discusses how chemicals can blur the line between he and she. For some animals, all it takes for a him to become a her is a few chemicals. Hear how endocrine disrupting chemicals have been shown to affect the sex in fish and the unique glowing biosensor fish that was developed as a diagnostic tool. This discovery will also draw links between these same chemicals and lower sperm counts in male humans, increases in various human cancers and obesity too! Alternative Careers: A Chemist’s Life at the Smithsonian February 7, 2013 Careers Channel Join James Blackman as he explains how chemistry intersects with history, art and biology at America’s greatest Museum. With over 19 different museums a zoo that cover everything from historical aircraft, mummies, priceless artwork and live tigers what is a chemist to do. Join James Blackman as he explains how chemistry intersects with history, art and biology at America’s greatest Museum. Available Furnished Start-Up Bio Lab (Chemical/Synthetic/Medicinal/Research) 4903 Morena Blvd., San Diego, CA 92103 This lab can produce 100 mg to 500 gm scale. Lab has 4 fume hoods including 1 biological fume hood. 1 LCMS Mass Spectrometer, 1 Prep HPLC, 1 ice making machine. Rent is $3700 ($2000 partial use)/month. Contact: Alex Jain at alexjain@yahoo.com Cell 858-663-4714 ACS Professional Education The ACS Department of Professional Education offers a variety of courses designed to help chemical scientists and technicians keep current in today’s competitive marketplace. We believe that finding the training you need to excel at your job or help you find a new one shouldn’t be that hard. That is why we offer in-person short courses and both live and on-demand webcast courses to help fit your schedule and travel budget. Short Courses Short courses are presented seminar-style, over anywhere from 1 to 8 days, and are taught by professionals who are excellent teachers as well as scientists. Courses are offered in convenient locations around the country. Webcast Courses Webcast courses are live, instructor-led courses that meet online over a period of weeks. With small class sizes and expert instruction, ACS Webcasts give you the opportunity to address your unique challenges and learn at your pace. On-Demand Webcast Courses ACS Professional Education knows how busy you are. So we've recently launched our on-demand catalog webcast short courses just for you. All of the modules are recorded for you to view at your convenience. On-Site Courses ACS Short Courses can even be scheduled for on-site presentation at your company or organization. The course content can be customized to meet the needs of the sponsoring organization. Contact ACS Short Courses Mailing Address: American Chemical Society, 1155 Sixteenth Street, N. W. Washington, D. C. 20036 Phone: 800-227-5558 x4508; 202-872-4508 Fax: 6336 E-mail: shortcourses@acs.org 202-872- Support: ACS Launches New Resources For Unemployed Chemists For unemployed chemists, belonging to a professional society like the American Chemical Society can offer opportunities to network, take advantage of career training resources, and stay connected to the chemistry community. “Putting our talented, creative chemists and chemical engineers and allied scientists back to work, that is the top priority for ACS, and to the extent that we can do that, that’s where we’re putting huge resources, both emotional and financial,” says Madeleine Jacobs, executive director and chief executive officer of ACS. “We want people to stay connected because that’s their best chance if they’re going to stay in the field.” To address the urgent needs of its unemployed members, ACS offers an extensive suite of career services, including several new resources: ◾ ACS has started online discussion forums on LinkedIn and the ACS Network to give unemployed members a venue in which to share experiences and job search resources. ACS career consultants are available to offer advice. ◾ Chemists can download a list of local and national jobhunting resources at http://www.acs.org/unemployed. The list, which includes job boards, job clubs, employer information, and other resources, is maintained by local sections and ACS Careers. ◾ ACS Careers is starting an online job club for unemployed members on Nov. 13. The group will meet virtually on Tuesdays, 2–3 PM ET. Participants will connect via Web conferencing to exchange job-hunting tips and support. Sign up online. For more information on these and other resources for unemployed chemists, visit http://www.acs.org/unemployed. http://www.cen-online.org November 5, 2012 UPCOMING EVENTS NICHOLAS M. DEAN, Ph.D., EXCALIARD PHARMACEUTICALS, INC. The Chemistry of a Successful Biotech Company: The Excaliard Story January 24, 2013 Dart NeuroScience, 10420 Wateridge Circle, San Diego, CA 92121 ********** MARTIN W. ROWBOTTOM, Ph.D., AMBIT BIOSCIENCES, INC. Discovery of CEP-32496, a Second-Generation BRAFV600EKinase Inhibitor for the Treatment of Cancer February 12, 2013 Sanford-Burnham Medical Research Institute, 10905 Road to the Cure, La Jolla, CA ********** SENIORS/RETIREES/CONSULTANTS/ ETC. BREAKFAST March 6, 2013 9:30 AM Marie Callender's Restaurant & Bakery, 11122 Rancho Carmel Dr., San Diego, CA 92128 ********** SAN DIEGO FESTIVAL OF SCIENCE & ENGINEERING FESTIVAL WEEK: March 16-23, 2013 EXPO DAY at PETCO Park: March 23, 2013 ********** THE 59th ANNUAL GREATER SAN DIEGO SCIENCE AND ENGINEERING FAIR March 19 - 24, 2013 Balboa Park Activity Center (2145 Park Blvd.) For information please see http://www.gsdsef.org/home.asp ********** 245th ACS National Meeting & Exposition April 7-11, 2013 New Orleans, Louisiana ********** EARTH DAY - EARTHFAIR 2012 April 21, 2013 Balboa Park, San Diego, CA http://www.facebook.com/events/374551439277386 ********** SUMMER PICNIC June 23, 2013 San Dieguito County Park, Solana Beach ********** FIFTY-/SIXTY-YEAR MEMBER LUNCHEON July 14, 2013 Vi at La Jolla Village 8515 Costa Verde Blvd.San Diego, CA 92122 ********** 246th ACS National Meeting & Exposition September 8-12, 2013 Indianapolis, Indiana ********* 2013 EXECUTIVE COMMITTEE & COMMITTEE MEMBERS SAN DIEGO SECTION OF THE AMERICAN CHEMICAL SOCIETY EXECUTIVE COMMITTEE Chair Erica Campbell-Conroy, Vertex Pharmaceuticals, EricaLConroy529@gmail.com Chair-Elect Mark Tichenor, Janssen Pharmaceuticals, Inc., mticheno@its.jnj.com Secretary William Tolley, Seacoast Science, Inc., b_tolley@juno.com Treasurer Bill Szabo, bszabo1@san.rr.com Councilors Thomas R. Beattie Hui Cai, WuXi AppTec Desiree Grubisha, CSUSM John Palmer, UCSD Ken Poggenburg David Wallace, Wallace Scientific Consulting Alternate Councilors Paul Bruinsma, Hewlett-Packard Company Surya K. De, Sanford-Burnham Medical Research Institute Julann Miller, Waters Corporation John Schindler Jim Shih, Eli Lilly & Co Ruo Steensma, Steensma Consulting, Inc. Members-at-Large Ryan Clark, Inception Sciences, Inc. Graeme Freestone, Helicon Therapeutics Mark Rosen, Janssen Pharmaceuticals, Inc. Patrick Andrew Staley Jean Wang, IriSys Inc. STANDING & SPECIAL COMMITTEES Awards Nomination Committee Thomas R. Beattie (Chair) Bylaws Committee Thomas R. Beattie Ken Poggenburg Ruo Steensma, Steensma Consulting, Inc. Bill Szabo William Tolley, Seacoast Science, Inc. ChemExpo Paul Bruinsma (Chair), Hewlett-Packard Company Julann Miller, Waters Corporation Communications Committee Julann Miller (Chair), Waters Corporation Paul Bruinsma, Hewlett-Packard Company Surya K. De, Sanford-Burnham Medical Research Institute Desiree Grubisha, CSUSM Ken Poggenburg David Wallace, Wallace Scientific Consulting Renate Valois (Newsletter Editor) EarthFair Julann Miller (Chair), Waters Corporation Education Committee Haim Weizman (Chair), UCSD Fundraising Committee Bill Szabo (Chair) Government Affairs Committee Ken Poggenburg (Chair) Law Committee Donald Lewis (Chair), Lewis|Kohn LLP Mad Science Program Thomas R. Beattie MedChem Symposium Thomas R. Beattie Membership Committee Mark Rosen, Janssen Pharmaceuticals, Inc. Nominations Committee Jim Shih, Eli Lilly & Co. Picnic Jim Shih, Eli Lilly & Co. Professional Development Committee Ruo Steensma, Steensma Consulting, Inc. Public Relations Committee John Schindler Retired Chemists Committee Ken Poggenburg (Chair) Will Harvey Seniors Breakfasts Thomas R. Beattie Women Chemists Committee Gulin Erdogan (Chair), SDSU Katie Duncan, TSRI Whitney Fies, Wildcat Discovery Technologies Isabelle Lerario, GNF Amanda Wolfe, TSRI Shanshan Yan, GNF Younger Chemists Committee Ryan Clark (Chair), Inception Sciences, Inc. Ben Pratt, Helicon Therapeutics, Inc. 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