January 2010 ENZYMATIC The Newsletter of the ASBMB Undergraduate Affiliate Network Inside this Issue A New Beginning EDITORIAL 1 A New Beginning 2 Science Outreach at Home and Around the World By Marilee Benore, University of MichiganDearborn ARTICLES 3 Applying to Graduate School: The Interview 6 The Ups and Downs of Summer Research 8 Tennessee Tech University UAN Creates Blueprint for STEM Outreach 10 Darwin Takes the Stage NEWS 13 Get Ready for the Inaugural USA Science and Engineering Festival! 14 ASBMB Science on the Mall Challenge 15 Welcome New UAN Chapters 15 ASBMB Biochemistry and Molecular Biology Honor Society RESOURCES 16 Molecules in Motion: Animated Movie Reviews A New Year and new ideas! Resolutions are great, but new plans, new places and new friends are even better. This issue of Enzymatic has opportunities for all of these! Faculty preparing for new classes should find the articles on outreach provide novel ideas to consider and incorporate. Advice for students on graduate applications and summer research opportunities will help students to go new places and meet new people. New ideas will get you a chance to go to Washington DC. If you have new ideas send them to us so we can share them in the next issue of Enzymatic. Enzymatic Contributors Marilee Benore, Editor, Professor of Biochemistry, University of Michigan-Dearborn Robert Jones, Student, University of MichiganDearborn Neena Grover, Associate Professor of Biochemistry, Colorado College Peter Kennelly, Professor of Biochemistry, Virginia Polytechnic Institute and State University Casey J. McCormick, UAN Chapter President, Tennessee Tech University Rebecca Smith, Parliamentary and Policy Officer, The Biochemical Society Weiyi Zhao, Manager of Education and Professional Development, ASBMB 1 Science Outreach at Home and Around the World By Neena Grover, Colorado College Each year, the Australian Museum presents the prestigious and much coveted Eureka Prizes. For excellence in “Promoting Understanding of Science” in 2009, the prize was given to Scitech, a hands-on museum in Western Australia, for developing science programs that turned every day games into experiments for children from pre-school to year 12, teachers, Aboriginal communities and the general public. Participants learn about light by playing with shadow puppets or about angles and trajectory by launching water bombs at their teachers. As the need for science outreach has become more apparent, outreach activities are getting more organized. Science Festivals are designed with the idea of bringing science to students of all ages and to the general public by using demonstrations, exhibitions, lectures, panel discussions, and workshops among other creative methods. Many of these festivals are annual events and involve participants in the exploration of science as relevant to everyday life. The umbrella organization, the European Science Event Association (EUSCEA, pronounced as “you see”), has 89 member organizations from 34 countries and focuses on organizing science festivals across Europe. South Africa has an annual SciFest Africa, a project of the Grahamstown Foundation, and features over 600 events and attracts approximately 60,000 visitors. It is modeled on the Edinburgh International Science Festival, which is believed to be the longest running science festival and was founded in 1989. Along with having the highest participation at its two-week festival, the Edinburgh International Science Festival also works with schools in Scotland during the year via its Generation Science program. In the United States, science outreach efforts are primarily limited to individual institutions. This year the very first USA Science and Engineering Festival will be held on the National Mall in October. Over 200 organizations have already signed up to host an exhibit. The Undergraduate Affiliate Network is running a competition to bring undergraduate students to the Mall to showcase various creative approaches of making science accessible. The details of the competition are in this issue of Enzymatic and on the ASBMB web site (see page 14). For more on science outreach, see the story by an undergraduate student, Casey McCormick, who describes how 100 high school students were introduced to DNA fingerprinting, and Rebecca Smith’s “The Darwin Project” on collaboration between The Biochemical Society and the Islington Community Theater to commemorate the bicentennial of Darwin’s birth. These stories will hopefully inspire all readers and UAN members to create their own outreach programs and enter the ASBMB Science on the Mall Challenge. To read more about the ASBMB Science on the Mall Challenge, go to page 14 of this issue. Or visit ASBMB online at: http://www.asbmb.org/News.aspx?id=4448 2 Applying to Graduate School: The Interview fulfilling graduate career. Both graduate admissions faculty and prospective major professors will be looking By Peter Kennelly, Virginia Polytechnic Institute for indications that you have the initiative, and State University inquisitiveness, and drive to develop into a Everyone knows that before making a major successful independent research scientist. investment such as purchasing a used car, Hence, good preparation is key. It will be the wise consumer personally inspects the expected that your decision to apply to their vehicle before signing on the dotted line. It program was the product of careful research therefore only stands to reason that, and thought. While there is no right answer when considering the investment to questions such as “What attracted you of several year’s time and effort to our program?” and “Why did you in the pursuit of an advanced decide to pursue graduate study degree, the prospective in Biochemistry and Molecular “Be prepared not only to graduate student should Biology?” your hosts will expect describe what you did, but take a prospective school you to be ready to respond the principles underlying for a “test drive” before to their inquiries concerning the experiment, i.e. how deciding whether to accept these topics. Similarly, if you are an offer of admission. does it work?” seeking to impress a particular While, in contrast to the professor with your eagerness used automobile market, to become a member of their the spectrum of prospective research team, be ready to provide graduate programs contains a well-articulated answer to the few outright “lemons,” an onquestion: “What interests you about my site interview can reveal a wealth of research?” information that can aid the prospective It is important to do your homework, so student in identifying those programs that best examine information about graduate programs match their interests and expectations. It also and their constituent faculty. Consult sources represents the opening step in recruiting the such as the Peterson’s Guide series, the major professor who will play a predominant American Chemical Society’s Directory of role in a student’s graduate education. Graduate Research, relevant departmental For the applicant whose knowledge and and faculty websites, and professors at your abilities are not fully captured by numeric home institution who may be alumni of or have measures such as grade point averages or connections to the institution. Think about scores on standardized examinations such your answers to likely questions in advance and as the GRE, an on-site interview offers the ask the faculty and graduate students at your chance to move beyond the numbers and current school about the types of questions garner an offer of admission. Whether you that commonly arise during a visit. Remember, are a feted guest whose invitation to visit given that so much information can be was accompanied by an offer of admission or accessed through the web, there is little excuse someone asking for an opportunity to convince for not knowing the basic characteristics of the an admissions committee, the interview can program such as the major areas of research serve as a launching point for a successful and activity of participating faculty. Continued on next page 3 Another likely topic of conversation will be any research experience you cited on your application. Be prepared not only to describe what you did, but the principles underlying the experiment, i.e. how does it work? Many students are surprised when someone asks them about how their project fit into the larger framework of their research mentor’s research program. However, your (in)ability to address this question will serve as an important indicator regarding the depth of your interest in science, the nature of your motivation, your willingness to take the initiative, and your capacity to grow. Programs and potential research advisors are looking for students who are not only talented, but who are inquisitive and self-motivated. So be ready to display these virtues when conversing about undergraduate research or internship experiences. While it is important to make a good impression on your hosts, an on-site interview also provides a priceless opportunity to learn more about the school. Before you sign on the dotted line, you should try to determine: • The nature of the process by which students are matched to major professors. • Whether faculty of particular interest to you are likely to have openings in their laboratory groups for new students. The Purdue University Interdisciplinary Life Science Ph.D. Program (PULSe) offers students a diverse range of research opportunities in the basic life sciences. These research areas include: Biomolecular Structure and Biophysics, Chemical Biology, Chromatin and Regulation of Gene Expression, Integrative Neuroscience, Integrative Plant Sciences, Membrane Biology, Microbiology, Molecular Evolutionary Genetics, Molecular Signaling and Cancer Biology, and Molecular Virology. For general information about PULSe, please visit http://www.gradschool.purdue.edu/ PULSe. Students from varied scientific backgrounds enroll in PULSe each year. While students who have completed courses in Calculus, Organic Chemistry, Biochemistry and/or Physics are often preferred, exceptions can be made for students who are changing fields. Research experience and reasons for selecting an interdisciplinary life science research program are strongly considered when making an admissions decision. For PULSe application details, please visit http://www.gradschool. purdue.edu/pulse/admissions.cfm • The manner in which students are supported financially. For what portion of your graduate career will you have to work as a teaching assistant? • Are benefits, e.g. health insurance, provided? • The average time for completion of the Ph.D. degree program. • The mechanisms by which student progress is evaluated. Continued on next page Cinthia Sanchez-Hernandez, 4th Year PULSe Graduate Student in the Molecular Virology Training Group Interested in this program? Visit the Purdue University graduate recruitment table during the Undergraduate Poster Competition at the 2010 Annual Meeting in Anaheim, Calif. 4 repetitive use of non-sequiturs such as “ya know”, “ah”, etc., or playing with your hair or jewelry. Your current school probably offers recorded mock interview services that enable you to identify distracting behaviors. Carry a copy of your schedule with you in order to help keep your interview on schedule and to demonstrate forethought and preparation. Remember, you are “One of most revealing questions you always on the record Listen carefully to the can direct toward a potential faculty during an interview. graduate students you meet. Any and everything you mentor is: What are your former Do not let one particular do and say potentially individual sway you in either a graduate students doing now?” may be considered. It is positive or negative direction. therefore prudent to avoid Look for the patterns across potentially controversial the group. Listen not only to what is said, but topics such as politics. It is generally inadvisable also for any obvious topics that are consistently to tell jokes as you may inadvertently offend avoided by either students or faculty. It is likely your host. Excessive criticism of your current that they are being avoided for a reason. If a school, previous instructors, or fellow students program does not offer you the opportunity to tends to generate a negative impression of you, meet with their students, be extremely cautious. the applicant. No program is perfect, but in general a good Avoid things that may impair your performance program can expect its students to provide or elevate stress. At meals, limit your alcohol visitors with a fair and positive impression. consumption to no more than a single glass Remember, whether it is for graduate or of beer or wine. Avoid spicy food, as well as professional school or for a job, you are in messy, hard to handle items such as soup, charge of making your interview a success. spaghetti, and other items laden with colorful While this might sound intimidating, this sauces or gravy. You don’t want to spend the objective generally can be accomplished afternoon wearing your lunch. Avoid excessive by implementing a few simple, common consumption of coffee or other liquids. It may sense practices. First, greet everyone you be a long time between bathroom breaks! Get meet with a smile and a firm handshake. a good night’s sleep so that you can be alert First impressions set the tone for the rest and focused. A successful on-site interview of the conversation. When in doubt, dress should be a win-win for both participants. conservatively with moderate, tasteful jewelry; Both parties should come away comfortable a minimal application of cologne or perfume; in their depth of knowledge of the other. And and subdued, tasteful make-up. Display remember, you are both working toward the attentive body language. Sit or stand facing the same goal: a good match between student person(s) you are interacting with. Look them and institution. So while it is important to be in the eyes. Sit up straight. Keep your hands prepared, you should not be intimidated. quiet when not speaking, e.g. fold them in your lap when you are seated. One of most revealing questions you can direct toward a potential faculty mentor is: “What are your former graduate students doing now?” If the graduates of a particular program or laboratory tend to progress to the kind of professional opportunities that you are interested in, it is very likely that they will offer you the opportunity to obtain the training you seek. Avoid distracting behaviors, such as slang or 5 The Ups and Downs of Summer Research By Robert Jones, University of MichiganDearborn Early in my undergraduate studies I found that I was fascinated with the complex and intricate molecular and biochemical events that underlie all biological development. The glitz of practicing clinical medicine was luring most of my colleagues in that direction, but I wanted to contribute in a different way. I decided that there was no better career path than that of the biomedical research scientist. What field could be more interesting? We get to spend everyday thinking about whatever fascinates us, and we are equipped with the tools to investigate even the most seemingly complex questions. I was interested in learning more about the aberrant signaling events that can lead to cancer development, I knew I’d need to get some experience to decide where I would like to specifically focus my attention. Although I was able to pursue research at the University of Michigan-Dearborn, there were no research opportunities in cancer biology. I knew I would have to find a way to gain more experience in order to be prepared for PhD programs. Furthermore, I wanted to make sure I was making an informed decision regarding my path in graduate school. I didn’t want to wake up one day and realize I had chosen the wrong field! I decided that a summer research experience would be a perfect opportunity and began searching opportunities for undergraduates. The number research opportunities was overwhelming. It took me over a month to pour through hundreds of programs and mentors and decide on which seven programs to apply. I prepared my applications meticulously and gave thoughtful consideration to each. At this point, I had one year of research working in an ecology lab on campus, so I was applying with very little related experience. After months of preparation, I submitted my applications with very high hopes. I soon realized how competitive these programs really are. I received many rejection letters explaining that there were literally hundreds of applicants for the few spots that were available. This was frustrating to say the least. After months of preparation I found there was less than a one percent chance of getting accepted to some of these programs. Fortunately, I got accepted to a National Science Foundation Research Experience for Undergraduates (NSF-REU) program at Western Michigan University. I worked in the lab of Dr. David Reinhold, studying the effects of environmental carcinogens on DNA repair mechanisms. This turned out to be one of the best experiences of my undergraduate career. Not only was I studying carcinogenesis and signal transduction under a remarkably helpful and knowledgeable mentor, but more importantly, I was learning what it takes to be successful in scientific research: passion and dedication. I spent at least sixty hours in the lab each week and loved every minute of it! The opportunity to commit fully to a project without the distraction and stress of coursework proved to be a truly rewarding experience. This experience also proved to be a good litmus test for students questioning their desire to pursue scientific research. Many students came in as pre-meds wondering if research was something they would enjoy, and many left knowing that research was not for them. For me, it solidified my desire to continue in research and energized me to spend the next year continuing to develop my laboratory experience and techniques. Continued on next page 6 I returned to my home institution excited to continue expanding on my abilities in the lab. I was fortunate to have a mentor, Dr. Marilee Benore, who is patient and encouraging. I spent the year developing my molecular and biochemical techniques and working hard on our project. I was able to present my research at the UAN regional meeting at the Argonne National Lab, as well as the 2009 Experimental Biology meeting in New Orleans. Attending the ASBMB national meeting proved to be one of the highlights of my undergraduate career. Not only was it a lot of fun, it was also a truly great opportunity to meet other young scientists with similar interests and aspirations and make great contacts with graduate schools and established researchers. After my first summer and year spent in research, I felt as if I had grown tremendously as a young scientist, and again applied to several summer programs. Again, I received rejections. This time however, I knew the challenges of being accepted to these programs, so I also too the initiative to personally contact several investigators whose research interested me. I was fortunate to find a position in a colon cancer lab at the Huntsman Cancer Institute at the University of Utah through one of these contacts. My experience at the Huntsman Cancer Institute (HCI) was unbelievable! My first month there felt like a dream. Everyone I worked with was extremely helpful and knowledgeable. The projects I worked on were exactly the type of research I was interested in, and I had a lot of freedom to pursue independent projects. The research environment at HCI is highly collaborative and the labs seem to work together seamlessly. This seemed to build a very healthy scientific community and fostered a great deal of productivity. I personally had the opportunity to work with people from multiple labs and even with physicians from the university hospital. The resources available were far greater than any lab I had worked in previously. I had the opportunity to learn many new techniques and work with things I would have never had the opportunity to work with at my home institution. All in all, this was an extremely rewarding experience on many levels and helped me define my research goals for graduate school. I was rather disappointed to leave HCI at the end of the summer, but I had to complete my coursework for graduation. Looking back, even though there was a lot of frustration associated with applying to summer research positions, I can’t imagine not having participated in them. It was well worth the work and frustration to gain the experience they provided. The two summer research experiences I participated in gave me an idea of what being a graduate student is like, as well as helped me define my own personal goals for graduate school. I strongly recommend applying to summer research programs to any undergraduate considering pursuing a career in research. Good luck! Summer research opportunities The ASBMB EPD webpage keeps a continuously updated list of 2010 summer research opportunities, graduate school funding opportunities and postdoctoral fellowship openings. Click here to view. If there are any opportunities that you would like to see posted on our website, contact Weiyi Zhao at wzhao@asbmb.org. 7 Tennessee Tech University UAN Creates Blueprint for STEM Outreach By Casey J. McCormick, Tennessee Tech University UAN Chapter President STEM (science, technology, engineering and mathematics) education outreach is a growing area of focus in the academic world today. It is important that we reach out to younger students to foster their interests in the pursuit of a career in STEM. At Tennessee Tech University (TTU) our UAN chapter recently developed a program to engage high school students in modern, hands-on activities in biochemistry and molecular biology that are both fun and educational. In a joint effort between the departments of chemistry and biology, and with the financial support from the ASBMB UAN Outreach Award, the TTU UAN chapter invited over 100 high school students from Monterey High School (MHS) in Monterey, Tenn. and Cookeville High School (CHS) in Cookeville, Tenn. to participate in a special K-12 outreach project called, “DNA Fingerprinting: A Modern Genetics Utility.” The project fell on two separate days in early Nov. 2009. Students were first presented with a brief lecture on the process of DNA fingerprinting. The talk included an introduction to the capabilities given to researchers, criminologists, and healthcare workers by DNA fingerprinting technology, and outlined the procedures involved in extracting and purifying DNA. The students also received a brief overview of cellular components that play a role in this type of analysis. At the end of the lecture, students were separated into two groups and participated in two laboratory activities. The first activity was the extraction and purification of DNA. The second activity introduced students to DNA fingerprinting. The fun really began with the extraction of DNA using a blender, green peas and “reagents” purchased from a local grocery store. These types of extractions are done frequently at high school science fairs. Our extraction protocol was based on one published by the University of Utah’s web-based Genetic Science Learning Center, reported in a recent article about science online in the October 2009 issue of ASBMB Today. The second activity allowed students to identify the possible perpetrator of a crime from a preprepared and developed agarose gel. Although this portion of the lab was not as “hands-on”, it definitely challenged the students and made them feel like real crime busters. Students had to identify the different samples in the gel using the DNA ladder. Students were presented a guided-inquiry packet that explained to them how to use the data and form conclusions. In addition to pinpointing the correct suspect, students compared the DNA fragments of each possible suspect and hypothesized on the relatedness amongst suspects. Continued on next page 8 At the end of each lab, a brief set of multiple choice and short answer questions were distributed. After the students had a chance to complete the “quiz,” proctors gave detailed explanations of all the correct answers. This helped to solidify what they learned in lab. The entire exercise was designed to give students insight into the procedures of “real” science, and many were surprised at how fun and easy it was. Students often have misconceptions about the level of complexity and the amount of time needed during scientific endeavors, something we like to nickname the “CSI effect.” The TTU UAN would like to acknowledge several individuals for their help with this project. We thank Mr. James Ventrice, a lab coordinator in the TTU Department of Biology, for his assistance in the preparation of the agarose gels and advice on experimental design. We also thank the TTU Department of Chemistry for opening its labs for our activities. Furthermore, we thank the ASBMB UAN for its support of the project through the outreach award. We couldn’t have done this without the support and contributions of all our collaborators. Students, teachers, and parents were highly impressed with the TTU outreach program. Students enjoyed the lab exercises, especially the extraction, and teachers were pleased that the TTU UAN has become a resource for their classes to experience higher-level science topics. The department of chemistry also received much praise from parents about the program. TTU UAN hopes to continue this program on an annual basis, providing new activities each year. TTU has nearly completed construction of its new STEM Center, which will provide many new resources for K-12 outreach. The TTU UAN hopes to use the STEM center as another resource to expand our outreach program for wider, more regional impact. We look forward to serving as a model for science outreach among all UAN institutions. 9 Darwin Takes the Stage By Rebecca Smith, Parliamentary and Policy Officer, The Biochemical Society In the year that saw the bicentenary of Darwin’s birth and the 150th anniversary of the publication of his seminal work, On the Origin of Species, the Biochemical Society, in collaboration with Islington Community Theatre, took to the stage to bring Darwin’s ideas to a new audience. I inherited the Darwin Project in the first half of this year after changes in our Education Department meant that the project was temporarily orphaned. The idea of a play around Darwin’s ideas was the brainchild of Education Committee Chair, Professor John Newbury, and our previous Head of Education. Although a new piece of theatre is not a traditional ‘science policy’ project, the opportunity to communicate science in a nontraditional way to, arguably, a nontraditional audience, could not be passed up. From a policy perspective, the debate about Darwin has itself evolved and now exists primarily in an educational setting where creationists argue that their beliefs should be always taught alongside those of Darwin. Indeed, this last year has seen its own controversies on this issue with the resignation of Michael Reiss from the Royal Society after his reported remarks about the teaching of creationism in Britain’s science classrooms, and the Texan state’s education board who considered recommendations that children be taught that there would be no United States if it had not been for God. The Darwin Project aims to bring the ideas of Darwin and evolution to young people in a way with which they can identify and engage. It was crucial that the characters in the play resonated with their audience, addressing the issues surrounding evolution from their perspective. The development and production of the play has been a highly collaborative effort. The dialogue in the play was constructed, in part, from the results of a week-long workshop which brought together the directors, actors, science communication volunteers, young people from Islington and the writer to explore the both the science and issues surrounding evolution through improvisation and discussion. The feedback from the workshop was even better than we had hoped: all the young people had both challenged and engaged with Darwin’s ideas. Ben and Dale (our science communication volunteers – affectionately termed ‘the science guys’ by the young people) managed to translate the complex scientific ideas around evolution for their audience and, over the course of the week, questioning them on anything and everything to do with evolution became par for the course. One of the teaching materials that they developed was a timeline of evolution which spanned the 5 days of the workshop. Although the first 4 days remained rather uneventful, the final day, in particular the last 60 minutes, were much more hectic. The finished play is called Hive 9 and centres around two central characters, Bea and Arron. Arron has recently gone to University to study biochemistry, leaving Bea behind, and returns to his friends over the summer to find that much has changed. Although he embraces Darwin’s ideas, in his absence many of his friends have joined ‘Hive 9’, an anti-Darwin group who believe that Darwin’s ideas mean that no‑one is special. As the activities of Hive 9 become more dangerous, it is up to Arron to get through to Bea, share his knowledge about Darwin and make sure that she knows just how special she is. Continued on next page 10 Quotes from the participants also show the impact of the workshop: “I’ve most enjoyed learning about evolution in a theatrical way” Hauk Pattison “I know a lot more about Darwin now to tell the truth. But I still feel the same because I believe parts of what Darwin said and parts of the Bible” Nickcolia King-n’da “It was much better than I could have imagined. Ben and Dale (science guys) for the win!” Daniel O’Keefe “I’ve never had to teach Darwin’s theories before, and look so closely at the social/ spiritual aspects... I was really surprised at how enthusiastic and insightful everyone was” Dale Bancroft “The project met my expectations – and more – I thought it would be education without fun, but it was the opposite” Hayley Thomas It is important to acknowledge those who have played key roles in creating Hive 9. The project team included: Ali Taylor (Writer) Ali’s play for theatre include A Little Neck (Goat & Monkey, Hampton Court Palace), Overspill (Soho Theatre and winner of Metamorphosis08 at Churchill Theatre Bromley), Cotton Wool (Theatre503), Porcelain (Royal Court Jerwood Theatre Upstairs, Workers Writes Festival). Ali was a delegate at Interplay Europe 2002, an international festival for young playwrights in Hungary and tutor at Interplay Europe 2004 in Athens. Ned Glasier (Director) Ned is the Director of Islington Community Theatre. He recently directed Success with Islington Youth Theatre, which was performed on the Olivier Stage at the National Theatre. Other recent work includes numerous community productions and projects for the Almeida Theatre, two plays for Company of Angels and You Me Us for Pyramid Theatre. Okorie Chukwu (Actor) Okorie has recently finished a 3‑year BA course in Acting at Mountview Academy of Theatre Arts. Prior to his training, he played Addie in One Shot and Dj Slammer in Sex Fm which both toured schools in North London. He also appeared as Grant in a rehearsed reading for the 2007 Kings Cross New Writing Award‑winning play Leonardo Stole My Crayon (Courtyard Theatre). At Mountview, he performed in Twelfth Night, Marat/Sade and Love Play. Okorie has recently performed in the ‘24 Hour Plays: Old Vic New Voices’ at the Old Vic. Suzie McGrath (Actor) Suzie trained at East 15 Acting School. Theatre credits include: When Cheryl Was Brassic (Nabokov), Crazy Love (Paines Plough & Oran Mor), Tracy Beaker Gets Real (Nottingham Playhouse). Television Includes Eastenders. Dale Bancroft (Science Communication Volunteer) Dale Bancroft is a student studying Biochemistry with Science Communication at Royal Holloway, University of London. When not lost in obscure science websites, Dale enjoys swimming, enjoying bad movies and generally always keeping occupied. Ben Storey (Science Communication Volunteer) Ben Storey is a student reading Physics with Science Communication at Royal Holloway, Continued on next page 11 University of London. When not having to contemplate the origins of the universe, Ben can be found trying to scrape the pennies together to explore a small part of it. The play was performed over 2 weeks in October and November in Islington schools by day and public performances by night. On its busiest day, in which three performances took place, over 100 students saw the play. The play has been seen in a variety of school environments, from the brand‑new science rooms at St Mary Magdalene Academy in central Islington to the much older hardwood laboratories at St Aloysius College. It has also been seen by a variety of audiences, including a single-sex audience at Highbury Fields School. Despite these differences, consistency is found in the reaction to the plot, where young people are engaged with the play and excited by the argument that it presents. Students are encouraged to question and debate the ideas discussed in the play after seeing it. Teachers and students have so far been really positive in their feedback about the play – with lots of different opinions aired in the question and answer sessions. Our favourite question so far (to Suzie, who plays Bea, and Okorie, who plays Arron) ... “do you two really fancy each other?” The Society is incredibly proud of Hive 9 and the efforts of all of involved in its production and delivery. There are many ideas about where we can take the play next in terms of both geography and development, and these are all being explored. The play has been professionally filmed and, once edited, will be available free of charge on the Society’s website along with the script and other teaching resources. The Darwin Project and the result, Hive 9 were conceived with the celebrations of Darwin’s Charles Darwin sketch by Marion Collier, 1878 birth and his pivotal work in mind, but it is somewhat fortuitous that the Biochemical Society should undertake such a project in a year which sees 50 years since The Two Cultures lecture by C.P. Snow in which he espoused that it was the breakdown between the “two cultures” of modern society – the sciences and the humanities – was a major hindrance to solving the world’s problems. To my mind, this project is an example of how the lines between the two cultures have been blurred to our advantage, explaining a fundamental scientific concept through the medium of the arts. I’d like to think that both Darwin and Snow would be proud of our efforts. If you would like to know more about the project, please visit our website http://bit.ly/darwinproject to find out more or email rebecca.smith@biochemistry.org Reproduced with permission, from Smith R., 2009, The Biochemist, 31 (6), 50-51 (c) the Biochemical Society. 12 Get Ready for the Inaugural USA Science and Engineering Festival! The first ever USA Science and Engineering Festival is slated to take place at our nation’s Capitol Oct. 10 - 24, 2010. The last two days of the festival will feature a large science expo on the National Mall. Over 300 organizations, such as NSF, NIH, EPA and of course ASBMB, have already signed up to participate. According to the organizers, “The Festival promises to be the ultimate multi-cultural, multi-generational and multi-disciplinary celebration of science in the United States. The culmination of the Festival will be a twoday Expo in the nation’s capital that will give over 500 science & engineering organizations from all over the United States the opportunity to present themselves with a hands-on, fun science activity to inspire the next generation of scientists and engineers.” The mission of the festival is to stimulate interest in science, technology, engineering and math (STEM) among today’s youth. This event received national attention during a recent speech to the National Academies of Science by President Obama. The President said, “So I want to persuade you to spend time in the classroom, talking – and showing – young people what it is that your work can mean, and what it means to you. Encourage your university to participate in programs to allow students to get a degree in scientific fields and a teaching certificate at the same time. Think about new and creative ways to engage young people in science and engineering, like science festivals, robotics competitions and fairs that encourage young people to create, build and invent – to be makers of things.” In addition to the planned activities in Washington, DC, schools, teachers, students and organizations from around the country are encouraged to participate by hosting their own satellite events. Organizers of the 2010 Festival have previously sponsored and organized the San Diego Science Festival with tremendous success. To learn more about the USA Science and Engineering Festival, visit: http://usasciencefestival.org/ Anaheim Awaits... Now that the abstracts are in and the first half of the school year is over, you can finally look forward to Anaheim! Here are a few events and dates to keep in mind: • • • • • • April 24 - 14th Annual Undergraduate Poster Competition April 25 - ASBMB 5K Fun Run. Sign Up Today! April 25 - Awards Presentation April 25 - UAN Committee Meeting April 26 - Screening of Naturally Obsessed: the Making of a Scientist April 25-27 -Poster presentation during main meeting for UAN award recipients (exact date and time to be announced in February). 13 ASBMB Science on the Mall Challenge! Would you like to visit Washington DC in the fall of 2010 and participate in the first ever USA Science & Engineering Festival on the National Mall? Take the ASBMB UAN Science on the Mall Challenge! Show us your creative side! Design a fun, hands-on biochemistry and/or molecular biology themed activity to take to the festival. It can be a dance, a song, a show-and-tell about your favorite subject in biochemistry or molecular biology. The goal is to create an interactive science outreach activity that is both informative and engaging. Some suggested categories to consider: 1. “The Molecules of Life” - The complexities of life arise from the interplay of a few different types of molecules, nucleic acids, proteins, lipids and carbohydrates. Explore the shapes and interactions of these “molecules of life” 2. “From Molecules to Medicine” - From drug design to individualized medicine, understanding the molecular basis of disease offers the potential for more effective treatments. See how the genomics revolution is leading to individualized treatments of various diseases. 3. “The Green Revolution: from Sunlight to Biofuels” - Plants capture the energy of sunlight- learn how the molecular life sciences are being used to convert sunlight to everyday useful forms of energy without producing the pollutants associated with fossil fuels and nuclear energy. 4. “Molecular Machines” - From muscle contraction to the movement of molecules within a cell, molecular machines play a critical role in the molecular life sciences. This exhibit will illustrate how molecular machines efficiently utilize chemical energy for mechanical purposes. Or come up with your own! The Prize: Submit your idea/skit/demonstration for the competition. All submissions will be judged by the ASBMB UAN Committee. If chosen, ASBMB will sponsor a pizza party for your entire UAN chapter. In addition, top finalists will receive travel stipends to come to Washington DC for the weekend of October 23 -24, 2010 to put on your show at the expo! Criteria for judging: • Creativity • Engagement • Interactivity • Content • Fun • Safety Submission format: • Short video clip • Written description with illustrations • Sound recording • Other How to submit: (pick one) • Upload it to YouTube and send us the link • Post to the ASBMB Facebook fan page (search for “American Society for Biochemistry and Molecular Biology” on FB and become a fan!) • Email to uancommittee@asbmb.org or wzhao@asbmb.org Submissions are accepted now through June 30, 2010. Questions? Contact Weiyi Zhao at wzhao@asbmb.org or 301-634-7352. 14 ASBMB Biochemistry and Molecular Biology Honor Society This fall, ASBMB officially launched the Biochemistry and Molecular Biology Honor Society (ΧΩΛ) for the UAN. The BMB Honor Society has been created to recognize outstanding juniors and seniors pursuing a degrees in the molecular life sciences for their scholarly attainment, research accomplishments and outreach activities. All UAN faculty advisors were invited to nominate their top students into ΧΩΛ. Online nominations took place between Nov. 15 and Dec.15. The UAN committee will be reviewing all nominees. Students will be notified on or shortly after Feb. 15, 2010. Students accepted into ΧΩΛ will receive an official honor society pin and certificate. Those who will be attending the 2010 Annual Meeting in Anaheim will be pinned by the Chair of the Education and Professional Development Committee, Dr. Ellis Bell, during the education award presentation. Help ASBMB Recruit Graduate Program Sponsors! We are looking for graduate programs to sponsor the 2010 Undergraduate Poster Competition. • $250 sponsorship fee • Recruitment table during the poster competition • School logo displayed online and in the event program • Deadline Feb. 26, 2010 • Click here for details. Contact Weiyi Zhao at wzhao@asbmb.org WELCOME NEW UAN CHAPTERS! The ASBMB Undergraduate Affiliate Network gained nine new chapters for the 2009-10 school year. They are listed here in alphabetical order: 1. Duquesne University in Pittsburg, Pa. Advisor: Dr. Jana Patton-Vogt 2. Eastern Kentucky University in Richmond, Ky. Advisor: Dr. Amanda Waterstrat 3. George Fox University in Newberg, Ore. Advisor: Dr. John M. Schmitt 4. Hartwick College in Oneonta, N.Y. Advisor: Dr. Andrew Piefer 5. Ohion Northern University in Ada, Ohio. Advisor: Dr. Kimberly M. Broekemeier 6. San Francisco State University in San Francisco, Calif. Advisor: Dr. Teaster Baird 7. University of Wisconsin Platteville in Platteville, Wis. Advisor: Dr. Chanaka Mendis 8. University of South Florida in Tampa, Fla. Advisor: Dr. Edward Seto 9. Vassar College in Poughkeepsie, N.Y. Advisor: Dr. Teresa Garrett We would like to extend a warm welcome to all new chapter members and faculty advisors. Click here to see a map of where these and other UAN schools are located. Be a Fan of ASBMB on Facebook! 15 Molecules in Motion Animated Movie Reviews Meiosis Animation by John Kyrk www.johnkyrk.com Reviewed by Anton Attard, University of Michigan Dearborn Score: 5 5 5 5 The different stages of meiosis are depicted in this animation, which can serve both as a great teaching tool in any biology classroom and as a quick review of meiosis for upperlevel college students. Juniors and seniors in college may forget the differences between meiosis and mitosis, and this animation is great for clearing up any confusion. I like this particular animation for its level of detail and the fact that you can review each phase of meiosis separately. Instead of a voice-over, the animation depicts what really happens, so it’s ideal for visual learners. I highly recommend this animation to any biology student or teacher. The Whole Brain Catalog - Two Conflicting Reviews Animation by Drew Berry www.molecularmovies.com As noted on the molecular movies web site, “The Whole Brain Catalog” is a video featuring the resource found at http://wholebraincatalog.org. Review 1 by Sara Semma, University of Michigan Dearborn Score: 2 3 4 it does a poor job explaining brain structure and function with its simple labels and lack of voice-over. For example, the animation shows the creation of a synapse but does not go into any detail whatsoever about what a synapse is. Although the music flowed beautifully and images were nice to look it, my opinion is that this video would not be helpful in a classroom setting. It is more entertaining than educational. 1 The animation in this video is riveting, however, having some knowledge of the brain, I felt that Review 2 by Dana Drysdale, University of Michigan Dearborn Score: 5 5 5 5 This animation, with its attention to detail, stunning special effects, and the use of perfectly simple yet beautiful music, creates a moving and inspirational video. Viewers will marvel over the complexity of the brain shown from the large scale observation of a mouse to progressively smaller observations of dentritic pathways and the formation of new synapses. The music does a simply marvelous job in aiding the animation, making the brain itself seem otherworldly. The lack of a narrator and the long, fast-paced sentences found in EDUCATIONAL other animations VALUE is replaced by the appearance of short ANIMATION ACCURACY STYLE terminology as new brain structures SPECIAL are observed; a benefit to those with photographic memories. This Excellent (5) - Poor (1) animation is top notch. 16