Hints for Remembering Medication Classifications Helpful When Studying for the NCLEX Exam Prefix or Suffix Cef- or ceph-cillin -mycin -cycline Likely Drug Classification Cephalosporin antibiotic penicillin antibiotic aminoglycoside or macrolide antibiotic tetracycline Example of a Medication in This Classification cefazolin, cephalexin ceftin bicillin penicillin G gentamycin, tobramycin erythromycin doxycycline minocycline -gliptin DDP-4 inhibitor for treating diabetes vildagliptin (Galvus) sitagliptin (Januvia) -oxacin a fluoroquinolone antibiotic Ciprofloxacin levofloxacin -azoles -mab -pine -pril -sartan -olol -ol -osin -parin -thiazide Precautions/Information to Know 5% cross sensitivity with penicillin Can cause GI distress Common allergy GI distress Renal toxicity , ototoxicity with aminoglycosides Dental problems (enamel discoloration) for fetus if taken in pregnancy or before age 8 Interferes with oral contraceptives watch for respiratory infections, headaches photosensitivity reactions indicates an antifungal Itraconazole fluconazole (Diflucan) clotrimazole ketoconazole miconazole (Lotrimin) indicates a daclizumab monoclonal antibody indicates a calcium amlodipine channel blocker (exception – verapamil doesn’t end in –pine) indicates an ACE captopril inhibitor indicates an valsartan angiotensin receptor blocker (ARB) indicates a beta propranolol blocker acebutolol very liver toxic, many drug-drug interactions indicates a beta agonist indicates an alpha blocker indicates an anticlotting agent indicates a diuretic albuterol rapid heart rate, sympathetic reaction doxazosin, prazosin first dose reaction; monitor for CHF heparin, dalteparin Injected; monitor for excessive bruising or bleeding weight loss, fluid & electrolyte balance polythiazide, hydrochlorothiazide injected, flu-like symptoms monitor BP, rhythm monitor cough not to be used during pregnancy monitor cardiovascular effects, caution with diabetics -ase -statin -triptan -enafil indicates an enzyme, usually used with thrombolytics indicates an HMG CoA inhibitor indicates and antimigraine drug indicates an impotence drug urokinase, streptokinase Monitor for bleeding lovastatin, pravastatin pregnancy category X, with diet and exercises, rhabdomyolysis monitor BP, cardiac effects zolmitriptan sildenafil -barbital indicates a barbiturate phenobarbital -pam indicates a benzodiazepine -lukast indicates a leukotrience receptor antagonist indicates a colony stimulating agent indicates an antisecretory agent -stim -prazole -setron -azine -sone -esterone -dronate -olone -asteride -profen indicates a centrally acting antiemetic indicates a phenothiazine indicates a corticosteroid indicates a progestin indicates a calcium regulator indicates an anabolic steroid indicates an androgen inhibitor Indicates an NSAID diazepam (exception: chlordiazepoxide does not end in –pam) zafirlukast filgrastim not with nitrates (can cause fatal hypotension) or alpha blockers; must be used with sexual stimulation CNS depressant, stimulates liver enzymes to metabolize drugs liver and renal toxic Asthma maintenance drug Not for use in acute asthma attack injected; check bone marrow omeprazole (Prilosec) Proton Pump Inhibitors (PPIs) are not for esomeprazole (Nexium) prolonged use: can cause hip fractures (exception – aripiprazole ends in –prazole and is an antipsychotic agent not in this classification) ondansetron, granisetron injected, CNS depression promethazine CNS depressant cortisone, prednisone timing of dose, risk of infection progesterone annual pap smear etidronate dosing details, monitor calcium androlone liver and heart toxicity dutasteride Monitor urinary output ibuprofen Monitoring GI bleeding