Human PATHOLOGY VOLUME 31 October 2000 NUMBER 10 Editorial Rodger C. Haggitt: A Biography On June 28th of the year 2000, the world of pathology suffered a loss of inestimable magnitude. On this day, Dr Rodger Haggitt was tragically shot to death by a resident, who then shot himself. Dr Haggitt was only 57 at the time of his death, but his legacy of excellence in education, research, and the practice of pathology has deeply affected the field of medicine and pathology. Dr Rodger Haggitt was one of the most influential gastrointestinal pathologists of our day. Dr Haggitt was born in Detroit, Michigan, where he lived until he was 11. Thereafter, he and his family moved to East Tennessee, where at age 16 as a laboratory assistant in a local hospital, he was first exposed to pathology. In this capacity, he discovered his life’s work while helping one of the pathologists to perform an autopsy. He continued working in the same laboratory after school, on weekends, and during summers for the following 6 years, and by the time he finished his undergraduate studies at East Tennessee State University, he had performed several hundred autopsies. During medical school at the University of Tennessee in Memphis, he helped support himself while increasing his knowledge of pathology by doing more autopsies in the evenings. After his first-year pathology course, he became a student prosector in the Department of Pathology and supervised and taught other medical students in the autopsy room. Thus, by the time he started his pathology residency at the Baptist Memorial Hospital in Memphis, under the direction of Eric Muirhead, he had already performed more autopsies than most pathology residents sitting for their AP boards today. He completed his pathology training at the New England Deaconess Hospital in Boston with Drs Shields Warren, William Meissner, and Merle Legg. Fresh out of residency and with a military obligation to fulfill, Dr Haggitt began his attending career at Tripler Army Medical Center, in Honolulu, Hawaii. Upon completing his military service, he was recruited Copyright © 2000 by W.B. Saunders Company doi:10.1053/hupa.2000.19981 back to Boston by Dr William Meissner and resumed his career as one of pathology’s rising stars. In 1977, Dr Haggitt returned to the University of Tennessee and the Baptist Memorial Hospital, where he was in charge of surgical pathology. In 1984, he moved to the University of Washington in Seattle, where he worked during the final 16 years of his illustrious career. The two major forces behind his decision to move to Seattle were the late Chairman of Pathology there, Dr Russell Ross, and Dr Cyrus Rubin, now Emeritus Professor of Gastroenterology and Pathology. Although Dr Rubin had himself made significant contributions to GI pathology, he served an unofficial residency in GI pathology with Dr Haggitt, and as a result became an attending in Pathology. The two became the very best of colleagues from that time forward, in research, teaching, and in the clinical practice of diagnostic GI pathology, not to mention their shared devotion for good wine, food, music, and art. Dr Haggitt’s interest in GI pathology developed during his residency years. Because there were no formal GI pathology fellowships at the time, he essentially taught himself GI pathology. At about this time, the era of gastrointestinal endoscopy with biopsy capability began, in large part due to his later colleague, Dr Cyrus Rubin, and Dr Haggitt focused on the interpretation of these specimens. He found that this required more knowledge of clinical medicine than any other aspect of pathology he had previously encountered, and he began to work closely with his gastroenterologist colleagues to gain this knowledge. He found this quite rewarding, as the information he obtained from the patient’s biopsy specimen, combined with the clinical information he had gotten from the clinician, made it possible for him to synthesize a comprehensive and clinically meaningful diagnosis. This gave him a strong sense of directly contributing to clinical decision making and patient care. This desire for clinical relevance is evident when one glances at Dr Haggitt’s CV. His numerous publications are always clinically relevant, and some have had a 1185 HUMAN PATHOLOGY Volume 31, No. 10 (October 2000) major influence on the practice of Gastroenterology. An example of the latter is his study of prognostic factors for adenocarcinoma arising in endoscopically resected colonic adenomas. He showed that the large majority of these lesions could be treated by endoscopic resection alone, sparing the patient the need for a colectomy. Dr Haggitt has worked with some of the foremost clinicians in the country. His collaboration with the late Dr Warren Nugent, chief of Gastroenterology at the Lahey Clinic, began when he was a resident and continued for over 20 years. Together, they published one of the first long-term prospective follow-up studies of neoplastic progression in ulcerative colitis patients and were able to show that endoscopic surveillance reduced the mortality from colorectal cancer in these patients. While he was in the Army at Tripler, Dr Haggitt worked with Drs Larry Johnson, the Chief of Gastroenterology, and Tom DeMeester, a thoracic surgeon, to establish esophageal 24-hour pH monitoring as the gold standard for the study of gastroesophageal reflux disease. In 1978, he and his colleagues at the Deaconess Hospital published a landmark study in which they documented that dysplasia was the precursor of adenocarcinoma in Barrett’s esophagus and suggested that its detection by endoscopic biopsy could be used to help control the risk of dying from cancer in these patients. Dr Haggitt continued his close collaboration with clinicians when he joined the faculty at the University of Washington. The ability to collaborate with outstanding basic scientists there added a new dimension to his research capabilities and interests. He continued his prospective studies on neoplastic progression in both Barrett’s esophagus and ulcerative colitis, now with a multidisciplinary research team including Drs Cyrus Rubin, Peter Rabinovitch, Teri Brentnall, Mary Bronner, and others. At the time of his death, he served as the principal investigator on an NIH-funded R01 grant on ulcerative colitis and was an investigator on several other federal grants. In addition to his work on premalignant lesions in the GI tract, Dr Haggitt worked with Dr Michael Kimmey and his colleagues in their pioneering work on the pathologic correlates of endoscopic ultrasound images. At heart, Dr Haggitt considered himself a “gut” oriented GI pathologist, but he has made several important contributions to hepatic pathology, as well. These include the first American description of nonalcoholic steatohepatitis, and with the surgeon James Williams at the University of Tennessee, the implementation of protocol hepatic allograft biopsies, first in canines and then in humans. These protocol biopsies are now standard practice in many transplant centers and have saved countless lives by preventing over immunosuppression. He and Dr Williams also authored the first description of functional cholestasis in hepatic allografts. Dr Haggitt was a dedicated and generous mentor to a generation of pathology residents and fellows. He also actively participated in postgraduate pathology education, where his efforts have had a great impact on the practice of pathology. Through his activities with the American Society of Clinical Pathologists, he taught more practicing pathologists and had more influence on the practice of GI pathology than any other single person working with that organization. Dr Haggitt served as the youngest ever ASCP Anatomic Pathology Council member and was its chairman. He received the Distinguished Service Award of the ASCP’s Commission on Continuing Education in 1989. He served the United States and Canadian Academy of Pathology as a member and subsequently moderator of the evening GI Specialty Panel, as a faculty person for summer Diagnostic Pathology courses, as a member of the Abstract Review Board, and as a member of the Council and on the nominating committee. He served on the Anatomic Pathology Test Committee of the American Board of Pathology for 7 years. Dr Haggitt was an invited speaker at numerous Gastroenterology and Pathology meetings and was honored with a number of named lectureships, including the Shields Warren Memorial Lecture of the New England Society of Pathologists, the David H. Sun Memorial Lecture of the American College of Gastroenterology, and the Professor CFA Culling Lecture for the National Society of Histotechnology. He was selected to represent the New England Deaconess Hospital at the symposium honoring the 150th anniversary of the Harvard Medical School in 1998 and received the Medal of the Swedish Society of Physicians in 1999. Dr Haggitt leaves behind a loving and devoted family. They include his beautiful and intelligent wife, Mary Jane, herself a talented pathologist, and their charming children, Kathryn, Scott, and Libby, now all married and 1186 EDITORIAL (Bronner & Rubin) parenting his grandchildren, Kate (born after Dr Haggitt’s passing but not before he saw her ultrasound picture), Hanna, Jordan, and Connor. Dr Haggitt also leaves behind his brothers, Mark and John Haggitt, and his sister Susan Woody and mother, Eldora Haggitt. In closing, Dr Haggitt’s personal qualities deserve mentioning. To those who have been fortunate enough to work with him and to come to know him, he was a private and quiet man, but one with a delightful sense of humor, a love for things of beauty, a kind heart, and an ever humble perspective. We will miss you Rodger, beyond all telling. MARY P. BRONNER, MD CYRUS E. RUBIN, MD Departments of Pathology & Medicine University of Washington Seattle, WA Rodger Haggitt, MD, in Memoriam Rodger Haggitt played a key role in the development of Human Pathology as a senior member of the editorial board since 1988. He helped to define the policies and set the standards for the Journal. He not only reviewed more than his fair share of manuscripts but often served as a referee, applying his tremendous breadth of knowledge, experience, and innate sense of fairness in resolving problematic issues. Human Pathology would be a far lesser publication were it not for the contributions of Rodger Haggitt. Fred Gorstein, Editor 1187