BMED/MSE4751:IntroductiontoBiomaterials
Spring2014
T/Th9:35‐10:55AM
ES&TL1205
Instructor:Dr.JohnnaTemenoff
Office:2112Whitaker
E‐mail:johnna.temenoff@bme.gatech.edu
OfficeHours:Tues1‐2pmorbyappointment
TA: ClaireSegar(csegar@gatech.edu)
TAOfficeHours:Byappointment
WebPage:http://tsquare.gatech.edu
BMED4751‐A,MSE4751‐A
(Pleasecheckwebpageregularlyforcourseannouncements.)
CourseObjectives:Toprovideabroad‐basedintroductionforundergraduatesto
differenttypesofbiomaterials(metals,ceramics,polymers)andthebody’snatural
responsestobiomaterialimplantation.Topicscoveredwillincludehowbasic
principlesinchemistryandphysicsresultinstructuralandfunctionaldifferencesin
biomaterialtypes(firsthalf),aswellasbeneficialanddetrimentalbiological
responsestobiomaterialimplantation(secondhalf).
Throughexaminationofreal‐worldexamples,eachstudentwillbeencouragedto
takeresponsibilityfordevelopingandusingknowledge(understanding)and
expertise(criticalthinking)inproblemsassociatedwiththefieldofbiomaterials.
Tohelpindevelopmentofthisexpertise,studentswillbepresentedwitha“microto
macro”viewofthecomplexsystemsthatarisewhenmaterialsareimplantedinthe
body,whichcanbeusedasaframeworkfordeterminingthemostimportantdesign
parametersandtestingtypesforspecificbiomaterialsapplications.
Prerequisite:MSE2001
Textbook:J.S.Temenoff,A.G.Mikos,Biomaterials:TheIntersectionofBiologyand
MaterialsScience.
Honorcode:StudentsareexpectedtoabidebytheGTHonorCode
(www.honor.gatech.edu).
Althoughdiscussionabouthomeworkproblemsisencouraged,eachstudentmust
completetheassignmentbyhim/herselfandturninanindividualanswerset.
Studentsaretoneitherreceivenorprovideinformationtoothersduringexams.
PlagiarizingisdefinedbyWebster’sas“tostealandpassoff(theideasorwordsof
another)asone'sown:use(another'sproduction)withoutcreditingthesource.”
Topreventbeingaccusedofplagiarism,quoteandattributeanywordsthatarenot
yourown,regardlessofwheretheyoriginated(website,book,etc.).
Useofanyprevioussemestercoursematerials(from“word”orfoundoncourse
webpage)isallowedforthiscourse;however,whiletheymayserveasexamples,
theyarenotguidelinesforanytests,quizzes,homework,projects,oranyother
courseworkthatmaybeassignedduringthesemester.
ForanyquestionsinvolvingtheseoranyotherAcademicHonorCodeissues,please
consulttheinstructor,theTA,orwww.honor.gatech.edu.
AnystudentsuspectedofacademicmisconductwillbereferredtotheOfficeof
StudentIntegrityatGeorgiaTech.
Lectures:Lectureswillbebasedoffmaterialinthebookandwillpresent
additionalexamplesanddemonstrations.Studentsarestronglyencouragedtoread
thecorrespondingpagesinthetextpriortoclass.Tomaintainanatmosphereof
respectintheclassroom,pleaserefrainfromtalkingoverothersorotherwise
degradingtheiranswersoropinions.Pleaseturnoffallcellphones,etc.priorto
enteringtheclassroom.
Grading:
Finalgradeswillbedeterminedbasedonperformanceonthefollowing:
Exam1‐25%
Exam2‐25%
Homework‐10%
OnlineQuizzes–10%
Participation‐5%
Final‐25%
Theminimumgradesthatwillbeassignedforthiscourseare:
Above89% A
Above79‐89%
B
Above69‐79%
C
Above59‐69%
D
59%andlower
F
Importantdates:
HW1due2/6
Exam1:2/18
HW2due3/27
Exam2:4/8
Final:5/1
Homework:Twohomeworksetswillbeassignedduringthecourseofthe
semesterandaredueatthebeginningofclassonthedatesfoundabove.Homework
setswillbeavailablefordownloadfromtheclasswebsiteby5pmontheday
indicatedonthesyllabus.YouareencouragedtoasktheinstructororTAs
questionsaboutthehomework,although,toexpediteyourlearning,youshould
attempttoanswertheproblemsonyourownbeforeasking.Solutionswillbe
postedontheclasswebsiteaftergradingiscomplete.Examplesofoldhomework
frompastyearscanbefoundontheclasswebsite.
Penaltyforlatehomeworks:
Inmyboxby5pmonduedate‐15%reductioningrade
Inmyboxby5pmonthebusinessdayafterduedate‐25%reductioningrade
Morethan1businessdaylate‐nocredit
Quizzes:Therewillbeatotalof3‐6open‐bookquizzesonTsquarethroughoutthe
semester.Thesewillbeannouncedatleastoneweekinadvanceandwillcover
materialinthetextbookand/orinlectures.Youwillbeallowedaminimumof24
hourstocompletethequiz.Solutionstothesequizzeswillbepostedontheclass
websiteaftergradingiscomplete.
Therewillbenomake‐upexamsforquizzes.Ifyouareforcedtomissaquizdueto
anemergency,youwillneedtoprovideappropriatedocumentationwithin1week
ofmissingthequiz,oryouwillreceivea0forthatquiz.Withproperdocumentation,
yourabsencewillbeexcusedandtheotherquizzeswillbeweightedmoreto
accountforthemissingpoints.
Exams:Therewillbeatotalof2closed‐bookexamsandacomprehensiveclosed‐
bookfinal.Examscan(andwill!)covermaterialinthetextbookthatisnot
mentionedinclasslectures,inadditiontothelecturematerial.However,themajor
emphasiswillbeontopicsdiscussedbothinthebookandinclass.
Thefirsttwoexamsarescheduledduringtheregularclasstimeonthedateslisted
above.Solutionstotheseexamswillbepostedontheclasswebsiteaftergradingis
complete.Examplesofoldexamsfrompastyearscanbefoundontheclasswebsite.
Therewillbenomake‐upexamsforExams1and2.IfyouareforcedtomissExam
1or2duetoillnessorfamilyemergency,youwillneedtoprovideappropriate
documentation(doctor’snote,etc.)within1weekofmissingtheexam,oryouwill
receivea0forthatexam.Withproperdocumentation,yourabsencewillbeexcused
andtheotherexamandfinalwillbeweightedmoretoaccountforthemissing
points.
IfyouneedtoscheduletotakeExam1or2early,pleasecontacttheinstructoratleast
1weekpriortotheexamdate.
Infairnesstoallofyourclassmates,participationinthefinalexamismandatory(no
exceptionsforgraduatingseniors).
Programmablecalculatorsmaynotbeusedonexamsandsharingofcalculators
duringexamsisnotpermitted.
Regrades:Regradesofhomeworks,quizzes,orexamswillbeconsideredifitis
handedbacktotheinstructorwithinoneweekofdistributionandincludesa
writtenstatementaboutwhyaquestionshouldbere‐graded.Pleasenotethat,if
handedback,theentireassignment(notjusttheprobleminquestion)willbere‐
graded,sotheoverallscoremayincreaseordecrease.
Specialaccommodations:Studentsrequiringspecialaccommodationsare
encouragedcontacttheinstructoroutsideclass.Resourcesandpoliciesforstudents
withdisabilitiescanbefoundathttp://www.adapts.gatech.edu/.
Tentative course outline: Dates Topic Week 1 Materials for biomedical applications (start 1/7) Week 2‐3 Chemical/physical properties of biomaterials (start 1/14) Week 4 Mechanical properties of biomaterials (start 1/28) HW 1 out 1/30 Week 5 Biomaterial degradation (start 2/4) HW 1 due 2/6 Week 6 Surface properties of biomaterials (start 2/11) Exam 1: 2/18/14 Week 7‐9 Protein and cell interactions with biomaterials (start 2/20) Week 10&12 Biomaterial insertion and acute inflammation (start 3/11) Wound healing and the presence of biomaterials HW 2 out 3/13 HW 2 due 3/27 Week 11 (3/18, 3/20) Spring Break Immune response and biomaterials Week 13 (start 4/1) Exam 2: 4/8/14 Week 14‐15 Biomaterials and thrombosis (start 4/10) Reading Chpt 1 Chpt 2‐3 Chpt 4 Chpt 6: 6.1‐6.2 only Chpt 5 Chpt 7 Chpts 8‐9 Chpts 10‐11 Chpt 12 Chpt 13 Week 16 Dead week (start 4/22) Lecture topics TBD Final: 5/1/14 8:00 ‐ 10:50 am, Period 10