WHY
OMEGA-RESEARCH.com?
OUR COMMITMENT
TO RESEARCH
The omega-3 fats found in fish and marine
algae, as well as GLA from borage and evening
primrose oils, offer support for many common
health conditions. Daily supplementation with
these essential nutrients may help maintain
health and lead to an improved quality of life.*
Visitors to Omega-Research.com will gain a
better understanding of the importance of
supplementing with EFAs.
Nordic Naturals is proud to sponsor
Omega-Research.com, an online resource library
for essential fatty acid (EFA) research, providing
published and objective third-party information
on omega-3 and omega-6 EFAs. However, our
dedication to clinical research does not end here.
We routinely participate in original EFA research
in an effort to help correct the global omega-3
deficiency. To date, over 30 original studies using
Nordic Naturals products have been published,
and more than 30 are currently in progress.
Omega-Research.com features:
n Research on omega-3s and specific
WHAT IS
OMEGA-RESEARCH.com?
systems in the body
n Research on omega-6 fatty acids, particularly
gamma-linolenic acid (GLA)
Omega-Research.com was developed by
Nordic Naturals with the goal of educating and
informing physicians, researchers, consumers, and
the media about the many health benefits of EFAs.
n Information on the safety of high-quality fish
oil, which is purified of toxins like
heavy metals, PCBs, dioxins, etc.
n Access to thousands of published
clinical abstracts on EFA research
n Unbiased information in an
organized and easy-to-use format
n Information collected from
public, online medical journals
n New research uploaded monthly
n Topics cover fish oil, omega-3 fatty acids,
Pure and Great Tasting Omega Oils
®
111 Jennings Drive, Watsonville, CA 95076
Toll Free: 800.662.2544 x1 | Fax: 831.724.5263
prosales@nordicnaturals.com | nordicnaturals.com
© Nordic Naturals, Inc. 2014
MKT-PL406_0514
vitamin D in cod liver oil, oleic acid,
plant-based essential fatty acids,
and gamma-linolenic acid
PUBLISHED RESEARCH USING NORDIC NATURALS
®
NORDIC
NATURALS—
A RESEARCH
LEADER
As a research-driven company,
our products are used in numerous
human clinical trials every year.
Without solicitation, leading research
institutions around the world,
including Stanford, Duke, UCLA,
Wake Forest, Indiana University,
Cedars-Sinai Medical Center, and
others, choose Nordic Naturals
omega oils for their clinical studies.
Many of these studies are funded by
the National Institutes of Health, which
requires rigorous documentation
of purity, potency, and stability of
the products used. As a research
leader in omega-3 nutrition, Nordic
Naturals is committed to correcting
the global omega-3 deficiency by
providing awareness of the proper
balance of essential fats, and stressing
the importance of a healthy diet and
lifestyle. We are dedicated to the
latest clinical research in order to
deliver the world’s safest and most
effective omega oils.
Organization
Investigation
Study Type
FISH OILS
Product Dose & Duration
Publication
adults
ProOmega®
6 soft gels/day 56 days
Neuropsychopharmacology
2005 Dec;30(1):S104
open label, clinical intervention,
pilot trial
children with autism/
Asperger syndrome
ProEFA®
1 soft gel/day 90 days
Autism-Asperger’s Digest
2005 Jan/Feb:36–37
fish oil and glucose uptake
with insulin present
dose finding, in vitro
skeletal muscle cells
Arctic Omega™, ProDHA™, ProEPA™, ProOmega® Diabetes
N/A
2006 June;55(6):A382
HANDLE® Institute/
Rays of Hope Orphanage, Mexico
fish oil and behavioral
outcomes in challenged children
open label, behavioral measures
orphaned children with
functional challenges
ProEFA® Junior
1–2 soft gels/day 180 days
Adoption Today
2006 Dec/Jan:38–39
University of Pittsburgh Medical Center
Pittsburgh, PA
fish oil and inflammation,
reduction of NSAIDs use
open label, retrospective,
non placebo-controlled
adults with non-surgical
neck/back pain
ProEPA
2–4 soft gels/day 75 days
Surgical Neurology
2006 April;65(4)5:326–331
VA New York Harbor Healthcare System
Brooklyn, NY
fish oil and anxiety measures
randomized, double blind,
placebo-controlled
adult substance abusers
ProEPA™
5 soft gels/day 90 days
J Clin Psychopharmacology
2006 Dec;26(6):661–665
VA New York Harbor Healthcare System
Brooklyn, NY
fish oil and decreased anger
in substance abusers
randomized, double blind,
placebo-controlled
adults in drug treatment
ProEPA™
5 soft gels/day 90 days
Psychiatry Res
2008 Jan 15;157(1–3):95–104
San Jose State University
San Jose, CA
effects of fish oil on cholesterol
subfractions (CAD risk predictors)
randomized, double blind,
placebo-controlled
healthy adults
ProEPA™ Xtra
3 soft gels/day 28 days
J of Am Dietetic Assoc
2008 Sept;108;9:A104
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
fish oil and exercise for cognitive and
neurological enhancement
controlled trial
animal study
ProDHA™
N/A 12 days
Neuroscience
2008 Aug 26;155(3):751–759
University of Pittsburgh Medical Center
Pittsburgh, PA
fish oil, lipid profiles,
and cardiovascular risk
open label, pilot trial
professional football players
ProOmega®
4 soft gels/day 60 days
Sports Health
2009 Jan;1;1 21–30
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
fish oil and exercise combination for
adult brain synaptic improvement
controlled trial
animal study
ProDHA™
N/A 12 days
Brain Research
2009 May 13
The Institute of Health, Queensland
University of Technology, Australia
fish oil compliance
and adherence study
double blind, placebo-controlled
dialysis patients
ProEPA™ Xtra
4 soft gels/day 84 days
Journal of Renal Nutrition
2010 March 18:1–5
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
fish oil and exercise combination for
balanced brain chemistry
controlled trial
animal study
ProDHA™
N/A 14 days
Neuroscience
2010 Jun 16;168(1):130–7
Indiana University Department of Kinesiology
Bloomington, IN
fish oil and Montelukost
on asthma
randomized, double blind,
placebo-controlled
asthmatic adults
ProOmega®
10 soft gels/day 42 days
PLoS ONE
2010 Oct 18;5(10): e13487
Flinders University School of Medicine
Adelaide, Australia
fish oil compliance
and adherence study
randomized, controlled trial,
clinical intervention
elderly (60+ yrs) hip fracture
patients with malnutrition
ProEPA™ Xtra
9 soft gels/day 42 days
Asia Pac J Clin Nutr
2011;20 (2):175–179
University of Vermont, College of Medicine
Burlington, VT
effects of fish oil on acute
lung injury/inflammation
randomized, double blind,
placebo-controlled
inpatients with acute lung
injury—hospitalized
ProOmega®
7.5cc enterally q6hrs up to 14 days
Crit Care Medicine
2011 Jul;39(7):1655–62
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
adequate levels of dietary DHA crucial for building
long-term neuronal resilience-plasticity in adulthood
controlled trial
animal study
ProDHA™
N/A 105 days
PLoS ONE
2011;6(12):e28451
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
DHA protection against reduced plasticity of
brain and spinal cord after brain trauma
controlled trial
animal study
ProDHA™
N/A 12 days
J Neurotrauma
2011 Oct;28(10):2113–22
The Cleveland Clinic
Cleveland, OH
fish oil effects on c-reactive protein levels
randomized, double blind,
placebo-controlled
adults
ProEPA™
3 soft gels/day 56 days
Clin Lipidol
2011;6(6),723–729
Medical Research Council
Gambia, Africa / UK
fish oil and GI health, cognition,
and morbidity in rural infants
randomized, double blind,
placebo-controlled
infants (3–9 months)
Arctic Omega™
½ teaspoon/day 168 days
Matern Child Nutr
2011 Apr;7 Suppl 2:89–98
California Clinical Trials Medical Group, Inc.
Glendale, CA
omega-3 to enhance antidepressant
response in major depressive disorder
randomized, placebo-controlled
depressed adults
ProEPA™
4 soft gels/day 63 days
J Clin Psychopharmacology
2012;32(1):61–4
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
“metabolic syndrome” in the brain:
deficiency effects of omega-3 fatty acids
controlled trial
animal study
ProDHA
N/A 42 days
J Physiol
2012 May 15;590(Pt 10):2485–99
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
high-fat diet transition
reduces brain DHA levels
controlled trial
animal study
ProDHA™
N/A 105 days
Sci Rep
2012;2:431
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
dietary therapy to promote neuroprotection in chronic spinal cord injury
controlled trial
animal study
ProDHA™
N/A 42 days
J Neurosurg Spine
2012 Jun 26
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
effects of diet containing omega-3 DHA
and curcumin on spinal cord learning
controlled trial comparative
animal study
ProDHA™
N/A 28 days
2012;7(7):e41288
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
dietary omega-3 builds resistance
against effects of traumatic brain injury
controlled trial
animal study
ProDHA™
N/A 21 days
PLoS ONE
2012;7(12):e52998
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
omega-3 deficient Western diet
and brain trauma
controlled trial
animal study
ProDHA™
N/A 105 days
PLoS ONE
2013;8(3):e57945
University of Michigan Institution for
Clinical & Health Research, Ann Arbor, MI
fish oil and immune health,
reducing allergy predispositions
secondary analysis of
randomized, placebo-controlled
pregnant women
ProEPA™ Xtra vs. ProDHA™
2 and 4 soft gels/day 42 days
Am J Obstet Gynecol
2013 Apr;208(4):316.e1–6
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
curcumin complements the action
of DHA on TBI pathology
controlled trial
animal study
ProDHA™
N/A 14 days
Neurorehabilitation and Neural Repair
2014 Jan;28(1):75–84
Oregon Health & Science University
Portland, OR
randomized, double blind,
placebo-controlled
senior adults with probable Alzheimer’s
disease or mild cognitive impairment
ProOmega®
3 soft gels/day 1 year
J Alzheimer’s Dis
2014 Jan 1;38(1):111–20
controlled trial
animal study
ProDHA™
N/A 98 days
Biochim Biophys Acta
2013 Dec 15. pii:S0925–4439(13)00359–1.
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
fish oil and alpha-lipoic acid in the
progression of Alzheimer’s disease
DHA preconditioning for building long-term
neuronal resilience against TBI incurred
during adulthood
DHA as crucial for supporting plasma membrane
function, interneuronal signaling, and cognition
controlled trial
animal study
ProDHA™
N/A 77 days
Penn State University Department of Nutritional
Science, University Park, PA
fish oils to raise omega-3 index (O-3I),
predictor of CVD mortality
randomized, double blind,
placebo-controlled, parallel group study
adult students
Arctic Omega
0–6 soft gels/day 6 months
Duke University Medical Center, Psychiatry
Durham, NC
fish oil and heart rate
variability in anxiety
open label, pilot trial
Pediatric Clinic
Tucson, AZ
fish oil + GLA in developmental
language and learning
Texas A & M University
College Station, TX
UCLA Neurosurgery and Physiological Sciences
Los Angeles, CA
Subjects
™
™
PLoS One
Exp Neurol
2013 Dec 18. pii:S0014–4886(13)00370–1.
™
J Am Heart Assoc
2013 Nov 19;2(6):e000513