Biographical Sketch
Andrea E. Kudwa
aek7z@virginia.edu
Education
106 Stadium Rd. #7
Charlottesville, VA 22903
(434)-882-4742 _________
University of Virginia, Charlottesville, VA
Fourth Year PhD Candidate, Neuroscience Graduate Program
Miami University, Oxford, OH
Master of Science, Zoology with Neuroscience concentration
August 1998 - August 2000
Hillsdale College, Hillsdale, MI
Bachelor of Science, May 1998
Major: Biology Minor: Chemistry
Continuing
Education
Jackson Laboratories, Bar Harbor, ME
42nd Annual Medical and Experimental Mammalian Genetics
Course, July 2001
Marine Biological Laboratory, Woods Hole, MA
2001 Summer Program in Neuroscience Ethics and Survival
Funding/Grants
• NIMH - Ruth L. Kirschstein National Research Service Award
(NRSA) entitled "Phytoestrogens, Brain and Behavior"
priority score = 137, percentile = 9.5%
• Neurobiological and Behavioral Development Training Grant
January 2002 - October 2003
• Sigma Xi Research Grant - June 2000
Professional
Associations/
Honors/Awards
• The Fifth Annual Conference on Sex and Gene Expression Graduate Student Travel Award
• Fine Science Tools Travel Award for SFN 2003 Meeting
• The 6th US-Taiwan Neuroscience Symposium on Estrogen
Actions in the Brain Travel Award - November 2003
• Society for Behavioral Neuroendocrinology Travel Award - June
2003
• NSF Travel Award - 2nd International Meeting, Steroids and
Nervous System; Torino, Italy February 2003
• National Institute of Mental Health and MBL Fellowship for the
2001 Summer Program in Neuroscience Ethics and Survival
(SPINES) - Marine Biological Laboratory, Woods Hole, MA
• Travel Awards – Miami University (1999, 2000)
• Outstanding Biology Senior of the Year, Hillsdale College, 1998
• Society for Neuroscience, Student Member (1999-present)
• Society for Behavioral Neuroendocrinology, Student Member
(2001-present)
• Endocrine Society, Student Member (2002-present)
Research/Work
Experience
Graduate Research, Department of Biology, University of
Virginia, Charlottesville, VA 22908 (Jan 2001 – Present)
Advisor: Dr. Emilie Rissman
• I am currently examining the involvement of both endogenous estrogen and
dietary phytoestrogens in sexual differentiation of the brain using an aromatase
knockout mouse model. In addition, I am investigating the interactions between
the classic estrogen receptors, α and β, in regards to their involvement in female
sexual behavior.
Graduate Research, Department of Neuroscience, University of
Virginia, Charlottesville, VA 22908 (Aug 2000-Dec 2000)
Advisor: Dr. Jeremy Tuttle
• I investigated the neuroprotective effects of Nerve Growth Factor (NGF)
in an Alzheimer’s human cell culture model exposed to amyloid protein using a
two-site enzyme-linked immunosorbent assay.
Graduate Research Assistant, Department of Zoology, Miami
University, Oxford, OH 45056 (Aug 1998 – Aug 2000)
Advisor: Dr. Lori G. Isaacson
• During my Master’s program, I investigated neuronal plasticity elicited by
exogenous nerve growth factor within extracerebral blood vessels, superior
cervical ganglia, trigeminal ganglia, spinal cord, and brain in an in vivo rat
model.
• Coordination and instruction of undergraduate research within the laboratory
Graduate Teaching Assistant, Animal Physiology (Zoo 305)
Department of Zoology, Miami University, Oxford, OH 45056
(Aug 1998-Dec 1998; Aug 1999-Dec 1999) Supervisors: Dr.
Robert Sherman and Dr. Dennis Claussen
Undergraduate Research Assistant, Howard Hughes Summer
Intern, Department of Zoology, Miami University, Oxford, OH
45056 (May 1997-Aug 1997) Advisor: Dr. Ronald L. Wiley
• Analysis of the effects of central command and intramuscular pressure on
blood pressure during isometric exercise
Cadaver Dissection Assistant, Hillsdale College, Hillsdale, MI
49242 (Jan 1995-May 1998)
• One of two undergraduate students performing all dissection preparations for
the Biology 307 and 308 Anatomy courses
• Helped direct laboratory procedures and oversaw gross anatomy review
sessions
Hillsdale College Physiology Laboratory Student Worker,
Hillsdale College, Hillsdale, MI (Jan 1995 – May 1998)
• Designed and implemented exercise rehabilitation programs and monitored
equipment usage and maintenance
Published
Manuscripts
Manuscripts in
Preparation
Published
Abstracts
Kudwa, AE, S.E. Shoemaker, K.A. Crutcher, and L.G. Isaacson. (2002)
Evidence for reduced transport of exogenous neurotrophin by aged
sympathetic neurons. Brain Res. Sep 6;948(1-2):24-32.
Shoemaker, S.E., A.E. Kudwa, and L.G. Isaacson. (2002) Sympathetic Ingrowth to the
Trigeminal Ganglion Following Intracerebroventricular Infusion of
Nerve Growth Factor. Brain Res. Nov 22;956(1):136-48.
Kudwa AE and Rissman E.F (2003) Double estrogen receptor α and β knockout
mice reveal differences in neural estrogen-mediated progestin receptor
induction and female sexual behavior. J Neuroendocrinol. 15(10):97883.
DeCouto SA, Jones EE, Kudwa AE, Shoemaker SE, Shafer AJ, Brieshke MA,
James PF, Vaughn JC, Isaacson LG (2003) The effects of
deafferentation and exogenous NGF on neurotrophins and neurotrophin
receptor mRNA expression in the adult superior cervical ganglion.
Molec. Brain. Res. 119(1);73-82.
Kudwa AE, Gustafsson JA, Rissman EF. (2004) Estrogen receptor β modulates
estradiol induction of progestin receptor immunoreactivty in male, but
not in female, mouse medial preoptic area. Endocrinology. 2004 Jun 17
[Epub ahead of print]
Kudwa A.E., Harada N, Honda S-I, and Rissman E.F. (2003) Phytoestrogens
modify the effects of aromatization and sex on estradiol-induced neural
progestin receptors in mice. (Exp. Biol. Med - in review)
Kudwa A.E., Dominguez-Salazar E, Cabrera DM, Sibley DR and Rissman E.F.
(2003) Dopamine D5 receptor modulates male and female sexual
behavior in mice. (J. Neurosci - in review)
Kudwa A.E., Harada N, Honda S-I and Rissman, E.F. (2003) Dietary Soy
Phytoestrogens Modulate Arginine Vasopressin Immunoreactivity. Soc
Neurosci Abstr.
Kudwa A.E., Cabrera D., Sibley D.R. and Rissman E.F. (2003)
Characterization of sexual behavior in dopamine D5 receptor null
mutant mice.
Kudwa A.E., Harada N, Honda S-I, and Rissman E.F. (2002) Dietary Soy
Phytoestrogens Modulate Progestin Receptor Induction. Soc Neurosci
Abstr.
Scordalakes E.M., Kudwa A.E. and Rissman E.F. (2002) Estrogen Receptor β
Co-localization with Arginine Vasopressin, Oxytocin and
Corticosterone Releasing Hormone in Mouse Brain. Soc Neurosci.
Abstr.
Kudwa A.E., Gustafsson J-Ǻ, and Rissman E.F (2002) Dopamine facilitates
display of lordosis behavior in male mice. Society for Behavioral
Neuroendocrinology Abstr.
Kudwa A.E., Erisir A, Gustafsson J-Ǻ, and Rissman E.F. (2002) Sex
differences in progestin receptor induction persist in the ERαβKO
Mouse. ENDO Abstr.
Kudwa A.E., Schank J.R., Gustafsson J-Ǻ, and Rissman E.F. (2001)
The Role of Estrogen Receptors α and β and Androgen Receptor
In Regulation of Progestin Receptor in Hypothalamic Nuclei. Soc.
Neurosci. Abstr.
Kudwa, A.E.; Schank, J; Honda, S-I; and Rissman, E.F. (2001) Aromatase
gene modulates sex differences in progesterone receptor induction by
estradiol. Soc. Behav. Neuroendo Abstr./Hormones and Behavior
Kudwa, A., S. Shoemaker, J. Janik, and L.G. Isaacson. (2000)
Immunohistochemical and biochemical analysis of sympathetic
ingrowth into the trigeminal ganglion following exogenous NGF. Soc.
Neurosci. Abstr. 26(1): 845.
Shoemaker, S., A. Kudwa, M. Brieschke, R.G. Sherman, and L.G. Isaacson.
(2000) Plasticity of p75 expression in the SCG following exogenous
NGF: effect of deafferentation. Soc. Neurosci. Abstr. 26(2): 1870.
Kudwa, A., S. Shoemaker, K. Hearring, R.G. Sherman, A. Shealy, S. Colombo,
and L.G. Isaacson. (1999) Evidence for reduced transport of
exogenous NGF by aged neurons in the superior cervical ganglion.
Soc. Neurosci. Abstr. 25(1): 1064.
Shoemaker, S., A. Kudwa, K. Crutcher, and L.G. Isaacson. (1999) Neuronal
plasticity in the trigeminal ganglion following intracranial infusion of
NGF. Soc. Neurosci. Abstr. 25(2): 1271.
Meeting
Presentations
Kudwa, A. and R.L. Wiley (1998) Central Command Vs. Intramuscular
Pressure Contributions to the Pressor Response to Isometric
Contractions
Oral Presentations at: •Michigan Academy of Sciences
Alma College, Alma, MI, February 1998
•Beta Beta Beta Biological Honor Society
Regional Convention, March 1998
•Beta Beta Beta Biological Honor Society
National Convention, June 1998