STUDY GUIDE
NEUROSCIENCES MODULE
SECOND YEAR MBBS
SEMESTER 3
LIAQUAT NATIONAL HOSPITAL
& MEDICAL COLLEGE
2015-16
LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
STUDY GUIDE FOR NEUROSCIENCES MODULE
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6.1
6.2
6.2.1
6.2.2
6.2.3
6.2.4
6.2.5
6.2.6
6.2.7
6.2.8
6.2.9
6.3
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2015-16
CONTENTS
Overview
Introduction to Study Guide
Learning Methodologies
Assessment Methods
Semester Examination Rules And Regulations of JSMU
Module 1: Neurosciences
Importance of Neurosciences
Objectives and strategies
Anatomy
Biochemistry
Clinical (Medicine, Neuro-Medicine, Radiology)
Community Medicine
Microbiology
Pathology
Pharmacology
Physiology
Research & Skills Lab
Skills &Practicals
Learning Resources
Modular Examination Rules And Regulations (LNMC)
Schedule
Page
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08
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
Module name: Neurosciences
Semester: Three
Year: Two
Duration: 6 weeks (Dec 2015 – Jan 2016)
Timetable hours: Lectures, Case-Based Learning (CBL), Self-Study, Practical, Skills,
Demonstrations, Visit to Wards & Laboratory
Credit hours: 6 credit hours in theory and 3 credit hours in practical
MODULE INTEGRATED COMMITTEE
MODULE COORDINATORS:
CO-COORDINATOR:
 Professor Zia-ul-Islam
 Professor Faiz Muhammad Sheikh
 Professor Nighat Huda
DEPARTMENTS’ & RESOURCE PERSONS’ FACILITATING LEARNING
BASIC HEALTH SCIENCES
CLINICAL AND ANCILLARY DEPARTMENTS
ANATOMY
MEDICINE
 Professor Karim Ullah Makki
 Professor Zia-ul-Islam
 Professor Faiz Muhammad Sheikh
BIOCHEMISTRY
NEUROMEDICINE
 Professor Jawed Altaf Baig
 Dr Naveeduddin Ahmed
 Dr. Hazim Brohi
COMMUNITY MEDICINE
 Professor Rafiq Soomro
RADIOLOGY
 Dr Muhammad Ayub Mansoor
PATHOLOGY
 Professor Naveen Faridi
MICROBIOLOGY
 Professor M. Khursheed Hashmi
RESEARCH & SKILLS DEVELOPMENT CENTER
 Dr Kahkashan Tahir
PHARMACOLOGY
 Professor Nazir Ahmad Solangi
PHYSIOLOGY
 Professor Syed Hafeezul Hassan
DEPARTMENT of HEALTHCARE EDUCATION
 Professor Nighat Huda
 Dr. Mirza Aroosa Beg
LNH&MC MANAGEMENT
 Professor Amir Ali Shoro, Dean & Principal, Director FHS
LNH&MC
 Dr. Shaheena Akbani, Controller A.A & R.T
LNH&MC
STUDY GUIDE COMPILED BY: Department of
Health Care Education
2015-16


Dr. Muhammad Suleman Sadiq
Dr. Rabia Mahmood
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
INTRODUCTION
WHAT IS A STUDY GUIDE?
It is an aid to:

Inform students how student learning program of the semester-wise module has been
organized

Help students organize and manage their studies throughout the module

Guide students on assessment methods, rules and regulations
THE STUDY GUIDE:

Communicates information on organization and management of the module.
This will help the student to contact the right person in case of any difficulty.

Defines the objectives which are expected to be achieved at the end of the module.

Identifies the learning strategies such as lectures, small group teachings, clinical skills,
demonstration, tutorial and case based learning that will be implemented to achieve the
module objectives.

Provides a list of learning resources such as books, computer assisted learning programs,
web- links, journals, for students to consult in order to maximize their learning.

Highlights information on the contribution of continuous and semester examinations on the
student’s overall performance.

Includes information on the assessment methods that will be held to determine every student’s
achievement of objectives.

Focuses on information pertaining to examination policy, rules and regulations.
CURRICULUM FRAMEWORK
Students will experience integrated curriculum similar to previous modules of the 1st & 2nd semesters.
INTEGRATEDCURRICULUM comprises of system-based modules such as neurosciences, head & neck,
endocrine which links basic science knowledge to clinical problems. Integrated teaching means that
subjects are presented as a meaningful whole. Students will be able to have better understanding
of basic sciences when they repeatedly learn in relation to clinical examples.
Case based discussions, computer-based assignments, early exposure to clinics, wards, and skills
acquisition in skills lab, physiotherapy department are characteristics of integrated teaching program.
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
LEARNING METHODOLOGIES
The following teaching / learning methods are used to promote better understanding:







Interactive Lectures
Hospital / Clinic visits
Small Group Discussion
Case- Based Learning
Practicals
Skills session
Self-Directed Study
INTERACTIVE LECTURES
In large group, the lecturer introduces a topic or common clinical conditions and explains the underlying
phenomena through questions, pictures, videos of patients’ interviews, exercises, etc. Students are
actively involved in the learning process.
HOSPITAL VISITS: In small groups, students observe patients with signs and symptoms in hospital or
clinical settings. This helps students to relate knowledge of basic and clinical sciences of the relevant
module.
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
SMALL GROUP SESSION: This format helps students to clarify concepts acquire skills or attitudes.
Sessions are structured with the help of specific exercises such as patient case, interviews or discussion
topics. Students exchange opinions and apply knowledge gained from lectures, tutorials and self study.
The facilitator role is to ask probing questions, summarize, or rephrase to help clarify concepts.
CASE- BASED LEARNING: A small group discussion format where learning is focused around a series of
questions based on a clinical scenario. Students’ discuss and answer the questions applying relevant
knowledge gained in clinical and basic health sciences during the module.
PRACTICAL: Basic science practicals related to anatomy, biochemistry, pathology, pharmacology and
physiology are schedule for student learning.
SKILLS SESSION: Skills relevant to respective module are observed and practiced where applicable in
skills laboratory or Department of Physiotherapy.
SELF STUDY: Students’ assume responsibilities of their own learning through individual study, sharing and
discussing with peers, seeking information from Learning Resource Center, teachers and resource
persons within and outside the college. Students can utilize the time within the college scheduled
hours of self-study.
ASSESSMENT METHODS:
Theory: Best Choice Questions (BCQs) also known as MCQs (Multiple Choice Questions) is used to asses
objectives covered in each module.

A BCQ has a statement or clinical scenario followed by four to five options (likely answer).

Students after reading the statement/scenario are supposed to select ONE, the most
appropriate response from the given list of options.

Correct answer carries one mark, and incorrect ‘zero mark’

Students mark their responses on specified computer-based sheet designed for LNHMC.
OSPE: Objective Structured Practical Examination

The content may assess application of knowledge, or practical skills.

A structured examination will have observed, unobserved, interactive and rest stations.

Observed and interactive stations will be assessed by internal or external examiners.
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LIAQUAT NATIONAL MEDICAL COLLEGE

2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
Unobserved will be static stations in which students will have to answer the question on the
provided response sheet.

Rest station is a station where there is no task given and in this time student can organize
his/her thoughts.
Internal Evaluation

During the module, students will be assessed to determine achievement of module objectives.

Module Examination: will be scheduled on completion of each module. The method of
examination comprises theory exam which includes BCQs, and practical (Objective Structured
Practical Examination).

20% marks of internal evaluation will be added in theory of semester exam. That 20% will
include class attendance, class tests and the modular exam which all have specific marks
allocation.
Example : Number of Marks allocated for Semester Theory and Internal Evaluation
Semester
Semester Examination
Theory Marks
80%
Internal Evaluation
(Class test + Attendance +
Modular Exam)
20%
Total (Theory)
100%
Formative Assessment

Individual department may hold quiz or short answer questions to help students assess their
own learning. The marks obtained are not included in the internal evaluation
More than 75% attendance is needed
to sit for the modular and semester
examinations
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
SEMESTER EXAMINATION RULES & REGULATIONS OF JINNAH SINDH MEDICAL UNIVERSITY
(JSMU)

In one academic year there will be two semesters. The semester duration is approximately
sixteen weeks.

Each semester may have two to three modules from two to eight weeks duration.
JSMU EXAMINATIONS:

JSMU will schedule and hold Semester Examinations on completion of each semester.

In one academic year, there will be two semester examinations and one Retake Examination.
MBBS Second year:
 Semester III examination is scheduled on completion of Neurosciences, Head & Neck and
Endocrinology Module.
 Semester IV Examination is scheduled on completion of GIT & Liver, Renal & Excretory and
Reproductive modules.
Examination Protocols:

In each semester, module will be assessed by theory paper comprising only MCQs. For
example semester 3 will have separate theory paper of Neurosciences, Head and Neck &
Endocrinology.

There will be one OSPE (Objective Structured Practical Examination) which will cover all three
modules of semester three.
1. Theory

Theory paper will comprise of 100 one best type MCQs.

Time duration for theory paper will be 120 minutes.

Students will mark their responses on JSMU specified response sheets assessed by computer
software.

It will carry out 80% contribution in theory results of the Semester.
2. OSPE:

It is to be held at the respective college unless specified by JSMU.

It may comprise between 12- 25 stations. Each station will carry 10 marks.

All students begin and end at the same time.

The content assessed is the same for all students

The time allocated for each station is the same.
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
3. JSMU Grading System

It will be based on GPA – 4 system
Marks obtained in
Percentage range
Numerical Grade
Alphabetical Grade
80-100
75-79
70-74
67-69
63-66
60-62
56-59
50-55
<50 Un-grade-able
4.0
4.0
3.7
3.3
3.0
2.7
2.3
2.0
0
A+
A
AB+
B
BC+
C
U

A candidate obtaining GPA less than 2.00 (50%) is declared un-graded (fail).

Cumulative transcript is issued at the end of clearance of all modules.
4. Retake Examination

The failures are to re-appear in subsequent examinations.

It is held once a year that is after the even number semesters. For example at the end of second,
fourth, sixth, eighth or tenth semester.

Retake examinations are for those students who fail in semester examinations, and who wish to
improve grades (GPA) secured in semester examinations.

The candidate who has passed the semester examinations with GPA less than 3.0 GPA may reappear in respective retake examination to improve grades.

MBBS first year Candidates failing in retake examinations may re-appear in semesters’
examinations of the following year. The format is exactly the same as in semester examinations.
EXAMPLE OF PROMOTION RULES:
A student who fails in Semester One Examination and passes Semester Two, s/he will take Retake for
Semester One Examination. S/he passes Semester Two and is promoted to 2nd year. If that student
FAILS in Retake, s/he will be promoted to 2nd year BUT will have to Pass Semester One examination in
Second year along with Semester Three and Four examinations for promotion to third year.
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
5. Promotion to next class

Students who pass both semester examinations are promoted from first year to second year.

Students who fail the MBBS first year semester retake examination will be promoted to second
year.

Students will be promoted from second year to third year and onward only if they have passed
the semester examinations of that year.

Clearance of all modules and their components of semester one to four are mandatory for
promotion from second year to third year (as per PMDC rules).

As per PMDC rules any candidate failing to clear a module or its component in four (1+3)
attempts is not allowed to carry out further medical education.

Clearance of all modules and their components of semester/s are mandatory for promotion
from third year onward.
(Albert Einstein)
2015-16
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
SEMESTER 3 MODULE 1 : NEUROSCIENCES
INTRODUCTION
Neuroscience is the study of the nervous system. It is a cross-disciplinary field that engages in investigating
how the nervous system develops and functions on a cellular level as well as the mechanisms that underlie
neurological disease. This module combines breadth of exposure to the field as a whole with the opportunity
for depth of experience in one of three central domains of neuroscience: Cellular and Systems, Functional and
Integration and Clinical Neurosciences.
When someone in the neighborhood develops stroke and the family wants to know what more can be done to
improve the patient’s lifestyle, or what are the chances his /her children will have stroke, it is our primary
responsibility as future doctors to know not just the treatment but also preventive strategies for a healthy
living.
Through this module you will develop an integrated, scientific knowledge that you can put into practice in a
clinical setting, plus creative and problem-solving skills. These key skills will prepare you for a career helping to
progress scientific discovery into clinical and medical practice, ultimately to improve human health.
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
COURSE OBJECTIVES AND STRATEGIES
At the end of the module the students will be able to:
ANATOMY
TOPIC
STRATEGY

Describe the development of brain (forebrain, mid brain & hind brain) &
spinal cord
Large Group Discussion

Explain the development of ventricles & meninges
Large Group Discussion

Explain the development of peripheral & autonomic nerves
Large Group Discussion

Enumerate the congenital anomalies of brain & spinal cord
Large Group Discussion

Discuss various malformations, developmental brain anomalies and
patterns of perinatal brain injury
Large Group Discussion

Describe the bony features of skull (adult and fetal) & cranial cavity
Small Group
Discussion/Case Based
Learning

Identify the features of cervical vertebra with their attachments
Small Group Discussion

Explain the meninges of brain & spinal cord with its neurovascular supply
and infoldings.
Discuss the Dural venous sinuses with their clinical importance
Small Group
Discussion/Case Based
Learning

Discuss the gross anatomy & cross sections of spinal cords at
different levels with its neurovascular supply
Small Group Discussion

Discuss the ascending and descending tracts with their clinical importance
Describe the formation of spinal nerves
Case Based Learning

Explain the gross structure of brain stem( medulla, pons and midbrain)
with its vascular supply, internal structure and illustration of cross sections
Large Group Discussion

Discuss the external and internal structure of cerebellum and fibres
associated with it
Large Group Discussion

Describe the gross features of diencephalon: thalamus, sub thalamus,
pineal gland and hypothalamus with their nuclei
Small Group Discussion

Discuss the organization of Autonomic Nervous system
Large Group Discussion
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE

Explain the ventricular system of brain, its abnormalities & formation &
circulation of CSF

Describe the cerebral hemisphere with surfaces, lobes, sulci and gyri and
explain the different cortical areas of brain with their functions and lesions

Describe the basal nuclei of brain & explain the major components of the
limbic system
Large Group Discussion

Describe the white matter of cerebral hemisphere: commissural,
association & projection fibers
Discuss the clinical correlation associated with the lesions of internal
capsule
Small Group Discussion

Describe the blood supply of the brain with clinical manifestations in
relation to the blockage and rupture of blood vessels
Large Group
Discussion/Case Based
Learning

Discuss the cranial nerves with their clinical significance

identify the normal radiological anatomy (CT scan, MRI) of brain
Small Group
Discussion/Case Based
Learning
Large Group Discussion/CBL
Case Based Learning
Small Group Discussion
BIOCHEMISTRY
TOPIC
STRATEGY

Identify chemical composition of nervous tissues, and explain types of
lipids in nervous tissues.
Lecture

Describe, classify and explain mode of action of Neurotransmitters
Lecture

Describe the metabolism of common neurotransmitters and their
metabolism:
I . Acetyl choline (Dementia and Alzheimers disease)
II . Dopamine (Parkinsons / Schizophrenia)
Lecture

Explain the serotonin metabolism and its disorders
Lecture

Identify energy needs of brain in normal and diseased state
Lecture

Explain the role of free Radicals in neurodegenerative process
Lecture

Describe the chemical composition of CSF in normal and abnormal
conditions
Lecture
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2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
LIAQUAT NATIONAL MEDICAL COLLEGE
CLINICAL SCIENCES
TOPIC
STRATEGY

Describe the clinical presentation and assessment of Parkinson’s
disease.

Describe the importance of blockage of vessels supplying the brain
and their clinical effects
Large Group Discussion/CBL

Discuss the clinical correlation of Cerebrovascular accident(CVA).
Large Group Discussion/CBL

Discuss epilepsy and its clinical features.
Large Group Discussion/CBL

Identify the radiologic features of lesions in the brain and spinal
cord on CT scan and MRI
Large Group Discussion
Large Group Discussion
COMMUNITY MEDICINE
TOPIC


STRATEGY
Know the importance of certain communicable / non communicable
diseases affecting nervous system in terms of prevention, fatality,
disability
Lecture
Describe the following diseases and its out breaks
o Endemic diseases of CNS
Lecture
o Poliomyelitis and prevention
Lecture
o Tetanus and prevention
Lecture
o Leprosy and prevention
Lecture
o Diphtheria and prevention
Lecture
o Stroke and prevention
Lecture
o Rabies and prevention
Lecture
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
MIRCOBIOLOGY
TOPIC

STRATEGY
Explain the etiology and pathogenesis of meningitis, encephalitis and brain
abscess
Lecture
PATHOLOGY
TOPIC
STRATEGY

Describe the pattern of nerve injury and their regeneration

Explain etio-pathogenesis of cerebral edema, hydrocephalus, raised
intracranial pressure and types of brain herniation
Lecture

Describe traumatic brain injuries and differentiate between different types
of intracranial hemorrhage
Lecture

List cerebrovascular diseases and know the consequences of ischemic,
hemorrhagic and hypertensive cerebrovascular accidents
Lecture
Small Group Discussion
PHARMACOLOGY
TOPIC
STRATEGY
INTRODUCTION TO AUTONOMIC NERVOUS SYSTEM





Describe the organization of ANS and systemic effects of stimulation
of sympathetic and parasympathetic nervous system
Name the major neurotransmitters in ANS and the steps in synthesis,
storage and release of neurotransmitters
Explain how drugs can affect different steps of neurotransmission
Name the major autonomic receptors in ANS, tissues where they are
located and explain their signal transduction mechanisms
Discuss the effect of activation of the various autonomic receptors
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Lecture
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LIAQUAT NATIONAL MEDICAL COLLEGE
PARASYMPATHOMIMETIC DRUGS





2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
List the types and location of cholinergic receptors and describe their
signal transduction mechanisms and effect of activation of these
receptors
Classify the cholinergic agonist drugs
Describe the pharmacodynamics and pharmacokinetics of directly
acting cholinomimetic drugs
Explain the mechanism of action of indirectly acting cholinomimetic
drugs
Discuss the signs and symptoms and treatment of organophosphate
poisoning
Lecture & Case-Based
Learning
MUSCARINIC RECEPTOR BLOCKERS





Name the muscarinic blocking drugs
Discuss the indications of muscarinic antagonists
Explain the adverse effects and contraindications for the use of
muscarinic antagonists
Describe the systemic effects of atropine
Describe the signs and symptoms and treatment of atropine
overdose
Lecture
NEUROMUSCULAR BLOCKING DRUGS




Name the nicotinic receptors, location and signal transduction
mechanism
Classify the neuromuscular blocking drugs and describe their
mechanism of action
Compare the depolarizing and competitive neuromuscular blockers
Discuss the pharmacodynamic and pharmacokinetic properties of
neuromuscular blocking drugs
Lecture
SYMPATHOMIMETIC DRUGS





Name the adrenergic receptors, location, signal transduction
mechanism and effect of activation of  and  receptor subtypes
Classify the sympathomimetic drugs an basis of their receptor affinity
and chemical structure
Compare catecholamines and noncatecholamines
Discuss basic pharmacology of epinephrine, norepinephrine and
isoproterenol and compare the cardiovascular effects of these drugs
Discuss other adrenergic agonists including, dopamine,
phenylephrine, methoxamine, clonidine, amphetamine, ephedrine,
MAO inhibitors etc
2015-16
Lecture
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LIAQUAT NATIONAL MEDICAL COLLEGE
ADRENOCEPTOR BLOCKERS




2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
Classify the  and  blocking drugs and describe their mechanism of
action
Describe the systemic effects, uses, adverse effects of  and 
blockers
Explain the contraindications of  and  blockers
Explain the rationale for clinical use of  and  blockers
Lecture
MANAGEMENT OF PAIN


List the types of pain
Discuss the clinical pharmacology of opioids, NSAIDS, and other drugs
used in pain management
Case-Based Learning
TREATMENT OF PARKINSON’S DISEASE




Describe the pathophysiology of Parkinson’s disease
List the causes of Parkinson’s disease including drug-induced
Parkinsonism
Explain the pharmacologic basis for use of levodopa, dopamine
agonists, MAO and COMT inhibitors, anticholinergic and amantadine
in Parkinson’s disease
Describe the therapeutic and toxic effects of antiparkinsonism drugs
Lecture +
Case-Based Learning
ANTICOAGULANTS, ANTIPLATELETS AND THROMBOLYTIC DRUGS








Classify the anticoagulants and describe their mechanism of action
Compare heparin and warfarin
List the uses, adverse effects of anticoagulants
Explain how to monitor anticoagulant therapy
List antiplatelet drugs
Explain the basis for use of aspirin as antiplatelet and its adverse
effects
Describe the mechanism of action and uses of other antiplatelet
drugs
Name the thrombolytic drugs, their uses, mechanism of action and
adverse effects
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Case-Based Learning
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2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
LIAQUAT NATIONAL MEDICAL COLLEGE
PHYSIOLOGY
TOPIC
STRATEGY

Define neuronal membrane potential and explain generation and
propagation of nerve impulse

Define synapse and enlist properties of synapses

Classify sensory receptors and explain their functions including pacinian
corpuscle
Lecture

Describe muscle proprioceptors along with their functions.
Lecture

Describe somatosensory pathways( dorsal lemniscal and antero-lateral).
Lecture

Describe somatosensory cortex
Lecture

Explain touch, pressure and temperature sensation

Explain the physiology of pain I
Lecture

Explain the physiology of pain II
Lecture

Describe functions of spinal cord and reflexes
Lecture

Explain motor, vital and non-vital functions of brain stem (respiratory,
cardiac, vasomotor centers and coughing sneezing and vomiting reflexes)

Enumerate physiologic correlates of various parts of cerebellum and its
functions
Lecture

Describe the basic neuronal circuit of cerebellum along with cerebellar
disorders
Lecture

Explain pyramidal tracts along with UMN/LMN
Lecture

List functions of Diencephalon ( Thalamus, Sub-Thalamus and EpiThalamus)
Lecture

Explain Extra pyramidal tracts of the motor cortex
Lecture

Describe functions and integration of Autonomic Nervous System I
Lecture

Explain functions of Autonomic Nervous System II
Lecture
2015-16
Lecture
Lecture
Small Group Learning
Small Group Learning
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE

Describe structures included in the basal ganglia and its disorders

Describe CSF formation and explain circulation and function
Small Group Learning

Describe Reticular Activation system, sleep and its disorders
Lecture

Explain functional description of limbic System
Lecture

Describe mechanism of learning and memory
Lecture

Explain speech and its related disorders
Lecture
Small Group Learning
RESEARCH AND SKILLS LAB
TOPIC
STRATEGY
LUMBAR PUNCTURE



Know the indications and contraindications of lumbar puncture
Know and recognize the potential side effects of the procedure
Identify the anatomical landmarks important in the procedure
Small Group Learning
(simulation based handson practice)
STROKE


Explain and apply the Suspected Stroke Algorithm
Discuss the 8 D’s of Stroke Care and explain why timely action is
important
2015-16
Small Group, Video based
interactive session
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
PRACTICALS & SKILLS:


Explain the microscopic features of nervous tissue, nerve & ganglion
Discuss the microscopic features of different parts of CNS: Cerebral & Cerebellar cortex

To analyze chemical composition of CSF in normal and disease state.
POWER LAB. EFFECTS OF CHOLINERGIC DRUGS ON RABBIT INTESTINE
 Identify the parts of a power lab and describe their functions.
 List the composition of Tyrode’s solution and functions of the components.
 Perform an experiment to show the effect of cholinergic agonist on rabbit ileum and interpret the
results.
 Show the effect of atropine on rabbit ileum and interpret the results.
POWER LAB: EFFECT OF CHOLINERGIC DRUG AND NEUROMUSCULAR BLOCKERS ON FROG RECTUS MUSCLE.
 To perform an experiment to demonstrate the effect of cholinergic agonist on frog rectus muscle and
interpret the results.
 To demonstrate the effect of a neuromuscular blocker on frog rectus and interpret the results.





Examination of Superficial Reflexes
Examination of Deep Reflexes
Cerebellar functions test
Measurement of Body Temperature
Electroencephalography
2015-16
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
LEARNING RESOURCES
SUBJECT
ANATOMY
BIOCHEMISTRY
COMMUNITY MEDICINE
PATHOLOGY/MICROBIOLOGY
RESOURCES
A. GROSS ANATOMY
1. K.L. Moore, Clinically Oriented Anatomy
2. Neuro Anatomy by Richard Snell
B. HISTOLOGY
1. B. Young J. W. Health Wheather’s Functional Histology
C. EMBRYOLOGY
1. Keith L. Moore. The Developing Human
2. Langman’s Medical Embryology
A. TEXTBOOKS
1. Harper’s Illustrated Biochemistry
2. Lehninger Principle of Biochemistry
3. Biochemistry by Devlin
A. TEXT BOOKS
1. Community Medicine by Parikh
2. Community Medicine by M Illyas
3. Basic Statistics for the Health Sciences by Jan W Kuzma
A. TEXT BOOKS
1. Robbins & Cotran, Pathologic Basis of Disease, 9th edition.
2. Rapid Review Pathology, 4th edition by Edward F. Goljan MD
1. http://library.med.utah.edu/WebPath/webpath.html
2. http://www.pathologyatlas.ro/
PHARMACOLOGY
PHYSIOLOGY
2015-16
A. TEXT BOOKS
1. Lippincot Illustrated Pharmacology
2. Basic and Clinical Pharmacology by Katzung
A. TEXTBOOKS
1. Textbook Of Medical Physiology by Guyton And Hall
2. Ganong ‘ S Review of Medical Physiology
3. Human Physiology by Lauralee Sherwood
4. Berne & Levy Physiology
5. Best & Taylor Physiological Basis of Medical Practice
B. REFERENCE BOOKS
1. Guyton & Hall Physiological Review
2. Essentials Of Medical Physiology by Jaypee
3. Textbook Of Medical Physiology by InduKhurana
4. Short Textbook Of Physiology by Mrthur
5. NMS Physiology
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2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
LIAQUAT NATIONAL MEDICAL COLLEGE
Students will be involved in Practical sessions and hands-on activities that
Hands-on Activities/ Practical
link with the neurosciences module to enhance the learning.

Labs
available.

Skill Labs
Utilize the lab to relate the knowledge to the specimens and models
A skills lab provides the simulators to learn the basic skills and
procedures. This helps build the confidence to approach the patients.
Video familiarize the student with the procedures and protocols to assist
Videos
patients.
Computer
To increase the knowledge students should utilize the available internet
Lab/CDs/DVDs/Internet
resources and CDs/DVDs. This will be an additional advantage to increase
Resources:
learning.
Self Learning is scheduled to search for information to solve cases, read
Self Learning
through different resources and discuss among the peers and with the
faculty to clarify the concepts.
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
MODULAR EXAMINATION RULES & REGULATIONS (LNH&MC)

Student must report to examination hall/venue, 30 minutes before the exam.

Exam will begin sharp at the given time.

No student will be allowed to enter the examination hall after 15 minutes of scheduled
examination time.

Students must sit according to their roll numbers mentioned on the seats.

Cell phones are strictly not allowed in examination hall.

If any student is found with cell phone in any mode (silent, switched off or on) he/she will be not
be allowed to continue their exam.

No students will be allowed to sit in exam without University Admit Card, LNMC College ID Card
and Lab Coat

Student must bring the following stationary items for the exam: Pen, Pencil, Eraser, and
Sharpener.

Indiscipline in the exam hall/venue is not acceptable. Students must not possess any written
material or communicate with their fellow students.
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LIAQUAT NATIONAL MEDICAL COLLEGE
2ND YEAR MBBS, SEMESTER 3 NEUROSCIENCESMODULE
SCHEDULE:
WEEKS
WEEK 1
WEEK 2
WEEK 3
WEEK 4
WEEK 5
WEEK 6
30th Nov 2015
NEUROSCIENCES
MODULE
MODULAR EXAM
WEEK 1
WEEK 2
WEEK 3
WEEK 4
WEEK 5
WEEK 6
8th January 2016
11 Jan-12th Jan 2016*
Jan 2016
th
HEAD & NECK
MODULE
MODULAR EXAM
WEEK 1
WEEK 2
WEEK 3
WEEK 4
MONTH
2nd YEAR SEMESTER 3
ENDOCRINOLOGY
MODULE
MODULAR EXAM
Feb 2016
Feb-March 2016*
March 2016
April 2016
April 2016*
PREPARATORY LEAVE
SEMESTER EXAM
April 2016*
*Final dates will be announced later.
2015-16
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