HUMAN PHYSIOLOGY 502
Course Syllabus*
Winter Term 2011
COURSE DIRECTOR:
Elizabeth M. Rust, Ph.D.
Office:
7708b Med Sci II
Phone:
615-3173
E-Mail:
emrust@umich.edu
Office hours:
Tuesdays, 5:15-6:15 in 7745 Med Sci II
Thursdays, 3-4 pm in 7708 Med Sci II (my office)
COURSE ADMINISTRATOR:
Michele Boggs
Office:
7744 MS II
Phone:
936-2355
E-Mail:
mboggs@umich.edu
THE COURSE:
This is an introductory graduate/advanced undergraduate course that covers the basic principles of cell
physiology and the functions of the major organ systems.
OBJECTIVES:
To describe physiological functions in terms of physical and chemical laws
To understand the functions of individual cells as the basis for understanding the functions of
organs
To demonstrate the coordination of physiological processes that underlies homeostasis- the
maintenance of a stable internal environment
To explain the role of different organ systems in maintaining homeostasis
TEXTBOOK:
VANDER’S HUMAN PHYSIOLOGY:
The Mechanisms of Body Function.
E.P. Widmaier, H. Raff and K.T. Strang
McGraw–Hill. 12th Edition with CONNECT.
LECTURE FIGURES:
Available on the web site. Contains most of the figures used in lecture.
Each unit will have its own folder. You may print or download them at your convenience to bring to
class. The files are either Powerpoint or PDF files, and slides are in color.
COURSE WEB SITE:
LECTURES:
Go to ctools.umich.edu/portal. Login. Click on the Physiol 502 tab.
M-W-F from 1:30 – 3:00 PM. 5330 Med Sci I, A wing.
Lecture will start promptly at 1:30 PM and end at 2:50 PM.
ONLINE (REQUIRED) INTRODUCTORY TUTORIAL AND QUIZ
On the Physiology 502 Ctools web site, in Resources, there is a folder titled “Required Tutorial”.
Within this folder are two files: (1) a Word file that has figures and associated notes and (2) a Link to
the online quiz in Lessons. This material will not be presented in lecture, so you should study this
material ON YOUR OWN (or with your classmates) and then take the quiz that is located in
UMLessons. The quiz has 10 questions and is worth 15 points. The questions and answers are
randomized and will change from one viewing to the next, so please pay attention. The quiz will be
available for you to take between January 5, 2011 and January 14, 2011. You MUST submit the
quizzes by 11:59 PM on January 14, 2011. You can take the quiz as many times as you want until you
*This syllabus is accurate as of 1/1/2011. The policies and information are subject to revision and/or modification at any
point at the discretion of the course director.
Physiology 502– Winter 2011
2
achieve either an acceptable score for you, or 100%. This quiz is required. If you do not take it you
will lose 15 points. The material on the Tutorial Quiz is NOT directly tested on the Unit Exams.
WRITTEN ASSIGNMENTS
There will be two written assignments worth 50 points each. They must be turned in electronically via
the web site. More instructions on completion and submission will come when the first assignment is
posted. Absolutely no leniency on submission requirements will occur unless you require
hospitalization or another similar major catastrophe which you can document occurs at/very near the
time of submission. In such a case, you must contact me as soon as possible to discuss submission of
your assignment.
REQUIRED: portable storage device such as flash drive, CD, or other such device. You must back up
your file and be prepared for internet connection or other computer mishaps.
Due Dates for Written Assignments
Assignment 1:
Monday, February 21, 2011
Assignment 2:
Friday, April 8, 2011
Examples of invalid late excuses (this is NOT a complete list):
“I thought I clicked submit”. It is YOUR responsibility to confirm that your assignment has been posted
to the web site. You will receive a confirmation email after submission. You should also open and check
what you posted after submission to be sure you submitted your final version of the assignment.
“My computer did something weird and the assignment disappeared”. Always save a backup copy on
disk or flash drive and save often!
“My internet connection failed” or “My computer crashed” or “I pushed submit at 4:57, but it didn’t go
through until 5:01”. Allow extra time for submission as it is not always instantaneous.
Cheating/Plagiarism Statement:
1.
You are responsible for the security of your electronic files and of hard copies of your documents. Do not
send or lend your submitted homework document to anyone else. If another student (or students) submits
your document, you will be held responsible and all students involved will receive a 0. Academic
misconduct charges may be brought against students in such a situation.
2. You may work together on the written assignments, but answers must be submitted in your own words.
Each of you has the responsibility of writing your answers in your own words. Each of you also has the
responsibility of protecting your answers and not allowing others the opportunity to cheat off of you. Do
not give your final answers (electronic or hard copy) to another student. If multiple students submit
identical or nearly identical answers, they will ALL receive a score of 0 for that question. Academic
misconduct charges may be brought against students in such a situation.
3. Plagiarism (copying) of internet, textbook or other resources without proper paraphrasing and/or citation
is also not permitted. All answers must be in your own words. Academic misconduct charges may be
filed if plagiarism is discovered. It is also unacceptable to quote resources, even with proper citation.
You must write the answer in your own words. Although not an academic misconduct issue, a quoted
answer with citation will receive a 0 for failure to follow instructions.
EXAMINATIONS
Course examinations will be based upon the subject matter presented in lecture and test questions will be
drawn from the lecture material. The textbook and posted readings are highly recommended for
supplementation and clarification, but test questions are not drawn solely from text readings. Lecture
material and lecture figures should receive priority when studying for the exam. Refer to each
lecturer’s instructions as to what material should be focused on when preparing for exams.
There will be 4 objective examinations in class and a comprehensive Final Exam. The objective
examinations will consist of multiple choice, matching and true/false questions.
Physiology 502– Winter 2011
EXAMINATION TIMES
Exam
Lectures
Examination 1
10 lectures
3
Questions/lecture
50 total questions
Day/Date/Time
Monday, 1/31/11
1:30-2:50 (in class)
Wednesday, 2/23/11
1:30-2:50 (in class)
Wednesday, 3/23/11
1:30-2:50 (in class)
Friday, 4/15/11
1:30-2:50 (in class)
Thursday, 4/21/11
4:00-6:00 PM
5 per lecture
Examination 2
9 lectures
45 total questions
5 per lecture
Examination 3
8 lectures
40 total questions
5 per lecture
Examination 4
9 lectures
45 total questions
5 per lecture
Final Exam
Cumulative
65 total questions
~2 per lecture
MISSED EXAMINATIONS – MAKEUP EXAMS
A Makeup exam is offered only for students who miss an exam because of illness, emergency or
approved/excused travel (e.g. sports competition, military service, other travel associated with university
business). Vacation travel will NOT be approved as an excused absence You must gain approval from
Dr. Rust BEFORE the exam for known absences, or as soon as possible if a sudden illness/emergency
arises. You MUST provide a documented reason, e.g. note from doctor or coach, for your absence from
the scheduled examination or you will not be allowed to take the Makeup Exam. If multiple students
miss an exam, an effort will be made to schedule the makeup exams together. Contact Dr. Rust for
approval of your absence and to schedule a makeup exam.
COURSE GRADES
THERE IS NO CURVE:
Exam or Assignment
Points Available Percentage of Final Grade
Exam 1
50
13.9
Exam 2
45
12.5
Exam 3
40
11.1
Exam 4
45
12.5
Final Exam
65
18.1
Tutorial Quiz
15
4.1
Assignment 1
50
13.9
Assignment 2
50
13.9
Total
360
100%
Exams = 68.1% of the grade; Assignments = 27.8% of the grade; Quiz = 4.1% of the grade
Course letter grades will be assigned on the following scale.
A+
97-100% B+
87-89%
C+
77-79%
A
93-96%
B
83-86%
C
73-76%
A90-92%
B80-82%
C70-72%
D+
D
D-
67-69%
63-66%
60-62%
E
F
50-59%
0-49%
Physiology 502– Winter 2011
4
LECTURE SCHEDULE
Unit 1: CELL PHYSIOLOGY/NERVOUS SYSTEM
Lecturer
W
Jan 5
Homeostatic control systems/transport across membranes
Rust
F
Jan 7
Chemical messengers, Membrane potential
Rust
M
Jan 10
Electrical signaling /synaptic transmission/signal integration
Rust
W
Jan 12
Structure of the nervous system/
Shore
F
Jan 14
Sensory Systems I
Shore
M
W
Jan 17
Jan 19
No Class- MLK Day
Sensory systems II
Shore
F
Jan 21
Motor systems
Sutton
M
Jan 24
Autonomic nervous system/neural control of hormone release
Sutton
W
Jan 26
States of consciousness/learning and memory
Sutton
F
Jan 28
States of consciousness/learning and memory
Sutton
M
Jan 31
Exam 1
Unit 2: MUSCLE AND CARDIOVASCULAR SYSTEM
W
Feb 2
Molecular basis of muscle contraction
Larkin
F
Feb 4
Muscle mechanics and metabolism, cardiac and smooth muscle
Larkin
M
Feb 7
Muscle
Larkin
W
Feb 9
Overview of cardiovascular system
Michele
F
Feb 11
Cardiac muscle structure and function
Michele
M
Feb 14
Vascular system and regulation
Michele
W
Feb 16
Regulation of mean arterial pressure and hemostasis
Michele
F
Feb 18
Cardiovascular system function in health and disease
Michele
M
Feb 21
Cardiovascular
Michele
W
Feb 23
Exam 2
F
Feb 25
Start Unit 3: Mechanics of ventilation
Saturday, February 26 – Sunday, March 6: Winter Recess
Rust
Physiology 502– Winter 2011
5
Unit 3: RESPIRATORY AND RENAL SYSTEMS (con’t)
M
Mar 7
Exchange of gases in alveoli and tissues
Rust
W
Mar 9
O2 and CO2 Transport in blood/Control of respiration
Rust
F
Mar 11
Overview of Renal System, Na+ and H2O excretion
Rust
M
Mar 14
Regulation of Na+, H2O and K+ excretion. Regulation of volume
and osmolarity
Rust
W
Mar 16
Problem solving- volume and osmolarity
Rust
F
Mar 18
Regulation of pH
Rust
M
Mar 21
Renal Failure/Diuretics
Rust
W
Mar 23
Exam 3
F
Mar 25
Unit 4: REPRODUCTIVE, GASTROINTESTINAL, AND
ENDOCRINE SYSTEMS
GI system overview/salivary glands, esophagus
Dempsey
M
Mar 28
Stomach, intestine, pancreas
Dempsey
W
Mar 30
Digestion and absorption of carbohydrate, protein and fat
Dempsey
F
Apr 1
Regulation of energy balance and body temperature
Simon
M
Apr 4
Hormonal Control of Metabolism
Simon
W
Apr 6
Regulation of growth, bone and calcium metabolism
Simon
F
Apr 8
Reproductive hormones, male reproductive system
Wishart
M
Apr 11
Female reproductive system
Wishart
W
Apr 13
Fertilization, implantation, pregnancy, contraception
Wishart
F
Apr 15
Exam 4
M
Apr 18
TBD
Th
Apr 21
Final Exam- Cumulative, 4:00 – 6:00 PM