Mitosis and Cytokinesis
(M Phase)
Mitosis
Overview of major cell cycle with focus on mitosis
Mitosis and Cytokinesis
Interphase: Most of cell cycle (G1, S, G2)
Mitosis: division of nucleus (organization of
chromosomes)
Cytokinesis: division of cytoplasm (actual cell split)
Memory Device for Mitosis!
"Please Meet At Terry Center"
"Pass Me All The Cookies"
Prophase
Metaphase
Anaphase
Telophase
Cytokinesis
PROPHASE
Chromatin condenses into
chromosomes
Mitotic spindle forms
Nuclear envelope breaks
down
(What is a mitotic spindle?)
Cytoskeleton proteins that
look like thin threads (also
called SPINDLE FIBERS)
Helps attach and separate
the chromosome copies
Spindle fibers shown in green
METAPHASE
Chromatids line up in the
MIDDLE of the cell.
Spindle attaches the
chromosomes at the
CENTROMERE
ANAPHASE
Individual chromosomes are
separated by the mitotic
spindle and move toward
opposite poles.
Telophase
Nuclear envelope reforms
Chromosomes unwind
Mitotic spindle breaks down
Cytokinesis
Cytoplasm gets pinched and
splits between the two newly
formed daughter cells
Overview
Prophase: cell prepares chromosomes and nuclear envelope
dissolves
Metaphase: chromatids in a line at the MIDDLE
Anaphase: Individual chromosomes move APART to
opposite poles
Telophase: nuclear envelope reforms and chromosomes
unwind
Cytokinesis: cytoplasm gets split in two and you have two
new cells
Plant vs Animal Cytokinsesis
Animal: cleavage furrow acts
like a belt
Plant: A new cell wall forms
at the center of the cell (cell
plate)