Anatomy & Physiology Chapter 26: Urinary System Introduction Name 1. Identify each of the following organs/structures of the urinary system and define their functions B.Ur; ^r- a prvC-H) ^\\v^\<reJ^'or'. C D.U^^P^5^ _ ^ D Anterior view o 20M PMTton E^xaUn. Inc..pubMm; SBStniamnCunrw^ Describe each of the following functions oi the Urinary System A. Excretion:^ qC^oAL B. Elimination: \)l56-y!(rty£^ cf VvTc^ \ \ r\ \ UTl'C C. Homeostatic Regulation: —\lo\vN^<- C/^ ("OWCt^WcVioi^ 0^" III. Describe how the urinary system is involved in the following homeostatic functions of the body... a. Regulating blood volume and pressure- b. Regulating ion concentrations of ions in the blood plasma f\^' ^V\d <r^ c. Stabilize blood pH d. Conserve nutrients e. Assist the liver IV. The Kidneys-General Info „ A. Location- 'f \2. leCTW-sWr IWiclVl- ^^ B. SizeAVeight- iGrvV^lovG ^-•> S o-s^rh ^ ^ '^.IQ 02 VaJiK V. Anatomy ofthe Kidneys- Shade and label the following structures within the kidney: Renal Cortex- yellow Renal Lobe-pink Renal Papilla- black < 'e«'Son £duca(«n. Renal Medulla-red Renal Columns- green Renal Sinus- brown Renal Pyramid-blue Minor and Major Calyx- orange VL Blood Supply to Kidney A. How much blood goes through the kidney? izoo B. Blood Flow- Use page 958 in your text for the following questions on blood flow into and out of the kidney 1. Fill in the names of the blood vessels that are found in the kidney in the flow chart below: Renal A r t e r y ^ A ^ i ' Vter\G)-)C..r W. ^ cortical radiate arteries (?\Ci Vv^ r I,\\lC j'.'•;' fi^^ efferent arterioles ^ p-^Pi-t'ub cortical radiate veins -> /\ U. \Jp jf 9 ^ -> Renal Vein 2. Label each of the above blood vessels in the diagrams below (omit efferent arterioles and peritubular capillaries- these are not visible in these diagrams) and color them red or blue to show oxygenated vs. deoxygenated blood flow: VII. The Nephron A. What is the function of the nephron? Where is it found in the kidney? Chapter 26: The Urinary System .1 The Nephron (pg 957-963) Name: Hu-A^::gr" Q Thefunctional units ofthe kidneys are known as nephrons. Nephrons are responsiblefor producing urine andfinalizing its concentration before it is sent to the bladder. Answer thefollowing questions related to these small but very important structures ofthe kidneys. 1. The two mmn structures ofthe nephron are the renal ( C \ ^ Wbw . 2. What nephron structure houses the glomerulus? and renal C 3. The blood vessel that delivers blood to the glomerulus is the W 4. The blood vessel that leaves the glomerulus is the 5. After the blood leaves the glomerulus, where does it go? \Kl pS frfOX/T p\ Vzy\pj\ Vb\A\€. 6. What key process occurs in the renal corpuscle? £ 7. The product ofthis process is known as i""l fG'rpU5i^k') 8. Once this product leaves the renal corpuscleit travels into the 9. This part of the nephron is responsible for 3 crucial functions. Please list them below: g C. wV pl/] l>(Cjhr<L \A..-C.M v..Ai:5 AM.,-, 10. The first part of the renal tubule is known as the And is made ofwhat tvne ofepithelial tissue? M Cl/b)0 SC) & yAlcrfAiilii What is the primary function of this part of the renal tubule? nra'r.o \^JO^'hc ^ 11. The next part ofthe renal tubule is known as theLo Qf \ And is made of what type of epithelial tissue? SCiIVj.mQS "f C^\DC)'\ (}'Qh What is the primary function of this part of the renal tubule? 12. The last part ofthe renal tubule is known as the HC I And is made of what type of epithelial tissue? What is the primary function of this part of the renal tubule? \\c V;)o--:Vc •J 13. Once the filtrate enters into the renal tubule, it is known as -Flu^'irf Why the name change? 14. Usingthe largerdiagram of the nephron on page 976j to ivj label lauv./! the iijt following luiiuwiii^ on uii the Ulc diagram: uiagicUJil. Loop-of-Henle Renal Tubule Collecting Duct Ascending Limb PCT" TTTT" Renal Corpuscle BCT Thin Descending Capsular Space Thick A,..di.g Bowman's Capsule,. Glomerulus Afferent Arteriole Efferent Arteriole DCT \!/\f |epKre>^ \ n , 15. Where does the tubular fluid go after the DCT? 16. What happens to it there? [KCSi\jL (fj i/\^j? f -!-(oa >5 1ir.g/?f rC-OW^rS [K)Okhe/r 17. List 3 differences between juxtamedullary nephrons and cortical nephrons in the space below: a. b. 'S.. of S<or-ohr^yP^' 3L-. i^lMC-t-iyv>a ) Rk(/>PJ^jft UreZ-VdA ' ^ l-\^w Uco^' Ot^S^fiTck^ C. R.egu\eAVc b\ooe} \ioVi^e> O'/t) Ht, SVvAC+uf^ C>b W bvcSAty '\^\l, OCV\ Prcgscrr^ 5^^^' '-( v\ . aWi.'^ Shmc(^l^ b i(orpyAii6 •f V>\\^C^'-f^ C!r> i'11 j '<, ^OOf(lc?\ Ae ij f'?X'6 mOst^L ^cil oi^erlvAvS) 'Z.. Rev\c^ TtAivi-e, -PtT J5, vv\)L« - Ldpb (joo-^ Yi^^fop tv,u^ ^ RtlJvb'Sor'pti WA - I " SeAre,+'''^'^ " [To^^_%0^ I I. Sem.+ion 1yj. . I c •% RccASyarp^lSiv^ - 1, V\o^W rmulcA^ b^ C\. CK»\V; yJ^PoTe-htj b. }sjc^(jf^^Ci - ^1 ^(5SfCfty-iO'C Vlcyr'if/h^^. •i+si ^«MCi ^srt :5 ixrt Pbl^C^vk V' ^":r.-^ ^ ^ " "2?:' ^ bw~-'- Afo»,v (l^) Vc;»^ ^ 626 Study Guide for Human Anatomy &Physiology 3. Figure 25.4 is a diagram of the nephron and associated blood supply. First, match each of the numbered structures on the figure to one of the terms fol lowing the figure. Write the terms in the numbered answerblanks. Then, color the structure on the figure that contains podocytes green, the filtering apparatus red, the capillary bed that directly receives the reabsorbed sub stances from the tubule cells blue, the structure into which the nephron empties its urine product yellow, and the tubule area that is the primary site of tubular reabsorption orange. / "V? Chapter 25 The Urinary System 627 Efferent arteriole erent arteriole Arcuate artery Arcuate vein Glomerulus Loop of Henle Collecting duct Tn terlnbnr nitfr)' Proximal convoluted tubule (PCT) Peritubular capillaries Distal convoluted tubule (DCT) 4. ^V^^\oV:)c-r' \|Cj>\ 9. tNr/M;rxK< 5. 10. ^ 15. 4. Circle the term that does not belong in each of the following groupings. \ 1. Renal pelvis Renal sinus 2. Adipose capsule Renal capsule 3. Juxtaglomerular apparatus 4. Glomerulus JG cells Vasa recta Glomerulus Vasa recta Glomemli Major calyx Renal fascia Macula densa cells Collecting duct Juxtamedullary nephrons Proximal convoluted tubule 7. Medullary pyramids Minor calyx Renal corpuscle Peritubular capillaries 5. Cortical nephrons 6. Nephron Renal pyramid Long loops of Henle Distal convoluted tubule Renal pyramids - Collecting ducts 5. Assign each of these urine-carrying ducts a number from 1 to 5, according to the path taken by the urine (the urine first passes through #1, then #2, etc.). 1. renal pelvis 3. papillary duct 2. ureter 4. major calyx Collecting duct r Chapter 25 The Urinary System 629 3. Figure 25.5 is a diagram of a nephron. Add colored arrows on the figure to show the location and direction of the following processes. 1. Black arrows at the site of filtrate formation. 2. Red arrows at the major site of amino acid and glucose reabsorption. 3. Green arrows at the sites most responsive to action of ADH (show direction of water movement). 4. Yellow arrows at the sites most responsive to the action of aldosterone (show direction of Na+ movement). 5. Blue arrows at the major sites of tubular secretion. Then, label the proximal convoluted tubule (PCT), distal convoluted tubule (DCT), loop of Henle, glomerular capsule, and glomemlus on the figure. Also label the collecting duct (not part of the nephron). Figure 25.5 n Anatomy & Physiology Chapter 26:Renal Physiology Name Use pages 974-976 in the text to answer the following questions: Nephron Loop (Loop of Henle): 1. What percent of the original filtrate has been reabsorbed by the PCT? 2. List two things that surround the Loop of Henle: a. b. ^;\vWo~ J/. Label the Loop ofHenle below with: thick, thin, ascending limb, desce^ingji 4. What two substances get reabsorbed from the Loop of Henle? 1 VifvVX ^ ^ / K (j^Dpof (( IfO 5. Using arrows, label the correct location and direction of movement of "a" and "b" on the Loop ofHenle to the right V 6. What separates the thin descending limb and thick ascending limb? "kr j^l -fubv1 -f\u 'A ^ j^if^ A 7. What is countercurrent multiplication? ^ i OP-fWlrj 8. Describe the permeability of the thin descending limb: (Pas^h^r Active Transport? 9. Describe the permeability ofthe thick ascending limb: ^ KIaI" Q- Solute concentrations change as tubular fluid travels from the PCX through the Loop of Henle to the DCT. Remember that the osmotic concentration (solutes) at the PCX is approximately 300 mOsm/L 10. What is being pumped outof thethick ascending limb into theperitubular fluid? 11. What effect does this movement have on the solute concentration (in other words, does solute concentration go up or down?): a. In the tubular fluid of the thick ascending limb? b. In the peritubular fluid between the ascending and descending limbs? J 12. What are the effects of #10 and #1 lb on the thin descending limb? 6^oyV\(j4-\C on:"-'vr\ s'A in "1^-A'f A \i ^ \ 13. What coj^t^dio&ofee^thii^escending limb? 14. As tubular fluid makes the turn at the bottom of the Loop of Henle moving up the ascending limb, what is true about the solute concentration? ik) ^ ' ' / \2oo 15. How does this solute concentration affect the transport of Na+ and Cl- into the peritubular fluid of the medulla? fAcMO'^.cj. \ 0^ Uc/\% ^Wicl 16. Why can't osmosis occur in the thick ascendinglimb? |H<- *1/ fv^ \ n \jj 17. How does this affect the solute concentration of the tubular fluid? 18. What is the concentration oftubular fluid by the time it reaches the DCT?' ift'l 19. Uesoibe an example of a positive feedback mechanism V, \ Below is a diagram of the permeability characteristics and solute concentrations of the tubular fluid as it passes through the ncphron. 1. What are: CORTEX ^✓""^utxjlar STEPS: •^Id from cortka! nephrore,,,...—- DCT and rEP'aPCT colieciing ducts ^Aj^^OO-300 Nutrients to'ciS'^'v STEP1: Gtomerulus Electrolytes .r 'STEP3: ,r PCT and descending .? Irntb m* * STEP 4:] ' TtliCk rX^O STEP 6; * DOTand K asc^KTtng Snib collecting ducts i .,L;;600 . \ AOH . * J ^ regulated , •/ @ -Cotransport (§) - Aldosteroneregulated pump: = Reabsorption = Secretion r Variable reabsorption Henle 'step 7: y.l-: .i^gqr^ Vasa recta * MEDULLA 2. Is this a cortical nephron or ajiuxtamedullarWephron? How do you know? permeability K'. f^oN?9 j7^) B Name ^ 6;^-^ -£. .A*,: j. ' . ^ ^ ' •••'• Date SfMrtinn •>vV;>*:. ^ E X '^R"c 1 S E'' •'-r .r .*-V MEWING VOlPPiiiiiPipif' A. Urinary System Structures Write the renal structure that the phrase describes. sdiposCTapstil^^ paBilhayducts majof caljTx —> PMnorctJyx Begharn- mp^n-,ir\ renal fascia renrf-pehlS^ renal hilus -renal-columno trnnl modullu . jgnakcadmi- renal papilla renal-j^rrafflfds "teBal.sinua 1. Urine-forming structure of the kidney. 2. Region ofkidney deep to cortex, contains collecting ducL 3. Extensions ofrenal cortex found in between renal pyramids. P^ipdloTij ( —rp.pb rey)J nApiWf^ —4. Urine flowing through this structure drains into aminorcalyx. 5. Located between renal fascia and renal capsule 6. Apex of renal pyramid. 7. Urine flowing through this structure drains into the renal pelvis. r^nc{i k;iu<? 8. Vertical fissure in concave surface ofkidney through which blood vessels and ureters pass. ^ 9 . Covers outersurface ofkidney, renP'j PrAo. LiJ2l 10. Dense irregular connective tissue that covers the adipose capsule and attaches the kidney to the abdominal wall. ——pA1Receives urine fiom the major calyces. 12. Space within kidney that is adjacent to renal meduUa, contains calyces and renal pelvis. Or 13^ Cuplike structure that is located in renal sinus that receives urine from openings of papillary ducts. —DliiVi P<^ Cone-shaped structures located within the renal medulla. f C}rfr. —15, Outermost region of the kidney, contains renal corpuscles. 619 3t Exercise 28 Urinary System StreetHre and Fnnctien E, Blood Flow Through the Kidneys ,race blood flow through the kidney. Start at the renal artery and number the blood vessels in sequence. £_ 1. Afferent arteriole u 2. Arcuate artery i i 3. Arcuate vein 1. 4. Efferent arteriole 1 _ 5. Glomerulus 6. Interlobar artery 7. Interlobar vein Udi\ok. \ ^ 9. __ 10. Peritubular capillary ^ 11. Renal artery 13 IZ Renal vein ^ 13. Segmental artery 623 — Exercise 2B OrinarT System Strnctpre and FnnctiBn 621 C. The Nephron V . • <3 stnicture(s) to adescription. Adescription may describe more than one structure, and astructure may be used more than once. afifeueiiLaae^ capsular space GoUectmg-ductS" distal eoiivoluiahiuUnle efferent arteriole filtration loop of Henle papillary ducts peritubular capillary bed pgQJumaliConvoluUifl tubule reabsorption renal corpuscle glomerular (Bowman's) capsule secretion glomerulus vasa recta — 1. Capillary loops that extend from efferent arteriole and run along loop ofHenle of juxtamedullary nephron. 1^^"^^^^ajorsecretion region ofrenal tubule. '^^'fe'A^o/ia^s^ve region of renal tubule. ^ 4. ADH acts here to increase water reabsoiption. 5. Blood vessel that delivers blood to glomerulus. fefe'^lood from the efferent arteriole flows into this capillary bed ( ' n^T 7. Aldosterone acts here to increase sodium ion reabsorption and potassium ion secretion. ^p! p^ LOU g. Structure that surrounds glomerulus and collects filtrate 9. Sections of renal tubule that descend into medulla. 10. Capillary network within the renal corpuscle. 11. Movement pfsubstances from peritubular capillary into renal tubule 0^-^ C/'f Q^-Ar^rAl 12, Suncture composed ofglomerulus and glomerular capsule. 13. Movement ofsubstances from renal tubule into peritubular capillary. ^ ^0/i p 14. Blood vessel that drains blood from glomerulus. 15. Process occurring across wall ofglomerular capillary and visceral layer of glomerular capsule that forms filtrate. ifiL ( MPili • fiMI»4»IP«l p. Urine Formation and Flow r Trace the flow offiltrate and urine through the uiinaiy system. Write the structures in order, starting with the glomeruius. 1. gomerulus 2. (2ApSi/W capsular space collecting duct 3. distal convoluted tubule 4. LOU 5. m. external uiethral orifice 6. C.C)\\eAk?^ A.LC-i- 7. ^ ckm^ loop of Henle major calyx minor calyx papillary duct proximal convoluted tubule renal pelvis ureter urethra s. urinaiy bladder 9. 10. f npi^cl uis t 11. Urv^r 12. V>i\e<Qlcigr 13. iArc!H>rvx 14. UrfAry.) ^r.,f 'CA (Cor\e%) I, T» Co C4"! C,i^) -" /-V 2. IS % ^ L.6H -^^'•ips {^f6[e'>5€6'' tVTrU-');^ Cortical nephron 1) fxkt: V/'"' 1 1) Re^lor^liOii - » «MA|f he J lA^k'V^ Juxtamedullary nephron:, / Cortex- pct^ u-w' C>tT, Ct) }Air\^iW 3) ^e^-rcr^ IMedulla hP f 11 It- ' Collecting l'il\:Ml l-)<v^bi,U,r P.,r j' papilla Renal (rc^»UviW\</.0 5^v>V2 Minor calyx SoVA^^/\.^ Co(7iisNO20MP9a«onEducBticn.Inc.. pubfidingaBSenjaimnCtmnni;*. Papillary ducts 'C^?e:fAbS<yr1[>|'i Oh 4^..--)o^/o \ ' \i;o U fiv\.^(^:f-<. b- • K e T c "Kb.,, y I Jr ^l-LiUw I *^ll ^ 1Crci^i-t'tA^ ^ IHiJ