Bone Imaging J.Lisý Anatomy – long bones • Diaphysis • Metaphysis • Zone of provisional calcification • Epiphyseal growth plate • Epiphysis Anatomy – long bones epiphysis metaphysis diaphysis growth (epiphyseal) plate zone of provisional calcification Epiphysis x Apophysis Epiphysis •articulates with adjacent bone Apophysis •doesn´t articulate with adjacent bone Epiphyseal or apophyseal plate should not be mistaken as fracture lines Osteolysis • focal decalcination decreased attenuation lucency (dark bone) • marginal osteolysis usuration, erosion Osteosclerosis • focally increased attenuation (white bone) chron. OM osteopetrosis Osteoporosis • less dense bone • loss of organic and anorganic bone • darker, lucent bone • compact, cortical bone thinner • white rim around bone Osteomalacia • reduced anorganic portion • darker bone • loss of cortical compact bone • Ill defined, hazy contours rachitis Periostal reaction periosteum is not normally seen 1) Spiculoid 2) Lamellar 3) Codman´s triangle Developmental dysplasia of the hip • orthopaedic examination and ultrasound • pathological finding is indication for X-ray investigation 1) osification of femoral head 2) course of the acetabulum 3) position of the hip joint Developmental dysplasia of the hip US Ultrasound alpha angle • the slope of the superior aspect of the bony acetabulum (normal greater than 60º) beta angle • depicts the cartilaginous component of the acetabulum (normal if less than 55º) evidence is insufficient to recommend routine screening for dev. dyspl. of the hip in infants as a means to prevent adverse outcome (U.S. Preventive Services Task Force, 2006) Developmental dysplasia of the hip X-rays X-rays 1) osification of femoral head 2) course of the acetabulum 3) position of the hip joint Craniosynostosis • premature closure of the cranial sutures • involved suture is narrow or is not visible • lacunar skull (expressive impresiones of brain gyri on the inner table of skull) Scaphocephalia brachicephalia Turicephalia Osteogenesis imperfecta • congenital fragilitas ossium • deficient formation of bone matrix and collagen • repeated fractures of different age • bizare deformities • bowed bones, extremities shorter, cortex thin Osteopetrosis (Albers-Schonberg) • failure of normal resorption of calcified chondral tissue • osteosclerosis • bottle-shaped metaphyses • sandwich vertebra • pathological fractures Mucopolysacharidosis Gargoylismus (Hurler´s type ) palm-leaf-shaped ribs maldevelopment of upper half of vertebral body (upside down parrot beak shaped ) coxa valga M. Perthes • • • • • most frequent aseptic necrosis etiology unknown head and neck of the femur 5th-10th year of age X ray signs delayed 6 weeks after clinical symptoms • bones shorter, unhomogeneous with foci osteosclerosis and osteoporosis • later fragmentation and deformity Other aseptic necrosis • Osgood-Schlatter (tuberositas of tibia) • Blount (med. condyle -tibia vara) • Koehler I (naviculare pedis) • Koehler II (head of MTT II) • Haglund (calcaneus) • Kienbock (lunatum) Scheuermann´s disease (juvenile vertebral epiphysitis ) etiology unknown around puberty Th spine • expressive kyphosis • wedge- shaped vertebral body • irregular margin of the vertebral body • Schmorl´s nodules Osteomyelitis acute • acute x chronic • specific x unspecific • X-ray changes delayed 10 to 20 days • soft tissue swelling • bone destruction • erosion Osteomyelitis chronic • periosteal reaction • irregular sclerotisation • sequestration, involucrum Brodie´s abscess • metaphysis of the long bones (most frequent femur) • circumscribed osteolytic area with sclerotic margin www.radiopedia.org Osteomyelitis sclerotisans Garré • unpyogenic • osteosclerosis • spindle-like diaphyseal enlargement Tuberculous spondylodiscitis • specific • early destruction of disc (lower intervertebral space) • later infection crosses vertebral endplates (higher intervertebral space) • complications paravertebral/epidural abscess Congenital syphylis ( lues ) • diaphysitis • metaphysitis (Wegener´s zone ) • periostitis Wimberger´s sign: erosions at the medial portion of the proximal metaphysis Rachitis (rickets) avitaminosis D Osteomalacia ( bone substituted by osteoid) • unsharp margins • tumbler-like deformity of metaphyses • rachitic rosary on the ribs Healing: • periostosis • doubled zone of the provisional calcification Scorbut (scurvy) avitaminosis C • Subperiosteal hematomas • Multiple epifyzeolysis Pelkan´s sign : sharp metaphyseal margins Winberger´s sign : sclerotic rim around porotic epiphysis Degeneration 1st grade • most common bone involvement • sharper margins of articular surface Degeneration 2nd grade • osteophytes Degeneration 3rd grade • • • • subchondral sclerosis subchondral pseudocysts narrow articular space periarticular calcifications Degeneration 4th grade • bone necrosis • (sub)luxation Bekhterev´s disease (spondylitis ankylosans) 1.Sacroiliac joints • subchondral osteoporosis • subchondral erosions (rosary sign) • ankylosis Bekhterev´s disease (spondylitis ankylosans) 2. spine thoracic • rigid • marked kyphosis • bamboo stick Paget´s disease (osteitis deformans) • enlargement of the bone • deformity (bone is bowed) • pathological fractures • osteosclerosis and osteoporosis • malignant degeneration is a serious, but infrequent complication Bone cyst • lucent focus within bone with an expansion effect • cortex can be thin Non-osifying fibroma • in metaphyses • eccentrical subcortical • occasionally multilocular Osteochondroma (cortical exostosis) • bone exostosis • always from metaphysis toward diaphysis • cartilaginous cup not visible Osteoma • bone only • round shaped shadow • sharp margins • paranasal sinuses Enchondroma • from chondral tissue (cartilage X ray lucent, invisible • defect in bone, often expansion effect, thin and perforated cortical contour • m. Ollier multiple chondromatosis of the bones Osteoid osteoma • diaphysis lower limbs • osteoplastic changes • nidus ( detectable CT ) round osteolytic lesion with small calcification Histiocytosis from Langerhans cells • Eosinophilic granuloma sharp demarcated osteolytic defect • Hand-SchullerChristian - map skull Osteosarcoma • osteolytic/ osteoplastic • periostal reaction laminated, onion-skin spicular (Sharpey ligg.) Codman´s triangle Osteosarcoma MRI • soft tissue part of the tumor - regression after chemo/radio therapy Ewing sarcoma Metastases • The next four tumors comprise 80% of all metastases to bone – Breast (70% of bone mets in women) – Prostate (60% of all bone mets in men) – Kidney – Lung • osteolytic (kidney, lung) • osteoplastic (prostate) • mixed (breast) • most common malignant bone tumors • most involve axial skeleton (skull, spine and pelvis) where red bone marrow is found • 90% of skeletal mets are multiple • Spinal mets destroy posterior vertebral body including pedicle pedicle-sign Metastases neuroblastoma Skull diploe