Organic Chemistry II Chemistry 262 – UNC Chapel Hill Fall 2014 Syllabus – Professor Moy OVERVIEW and INSTRUCTIONAL GOALS Organic chemistry is the study of carbon-­‐based molecules and these molecules are the building blocks of all living systems on Earth! This course will challenge you to think about the structure and behavior of molecules. Chem262 is the second half of a two-­‐semester course in organic chemistry. We will examine the chemistry of aromatic compounds, carbonyls, carboxylic acid derivatives, amines, and biological molecules such as carbohydrates and proteins. Over the course of this semester you will: -­‐ Enhance critical thinking and problem solving skills -­‐ Learn to make reasonable predictions of reactivity based on compound structure -­‐ Understand reaction mechanisms in terms of the flow of electron density -­‐ Use synthetic transformations to plan multi-­‐step synthesis of complex compounds -­‐ Apply fundamental ideas of organic structure and reactivity to issues of interest to society PREREQUISITE Chem261 or 261H. C-­‐ or better required in prerequisite. COURSE MATERIALS Required Materials Textbook: Organic Chemistry, 6th ed. UNC-­‐CH custom edition Clicker: Registered Turning Point Clicker Optional Materials Molecular Visions Organic Model Kit The Art of Writing Reasonable Organic Reaction Mechanisms, 2nd ed. By R.B. Grossman Study Guide and Solutions Manual for Organic Chemistry, 6th ed. P.Y. Bruice UNC-­‐CH custom edition; ISBN 9781256844860 ACADEMIC HONESTY Policy adopted by the faculty of the Department of Chemistry on September 9, 1977: “Since all graded work (including homework to be collected, quizzes, papers, mid-­‐term examinations, final examinations, research proposals, laboratory results and reports, etc.) may be used in the determination of academic progress, no collaboration on this work is permitted unless the instructor explicitly indicates that some specific degree of collaboration is allowed. This statement is not intended to discourage students from studying together or working together on assignments which are not to be collected.” The UNC Honor Code (available at honor.unc.edu) is the cornerstone of academic integrity at UNC. I expect all students to abide by the Honor Code at all times, whether in or out of class. While I do not anticipate any problems, I do not hesitate to report infractions. Please note that Honor Code violations include enrolling in a class for which you do not have the appropriate prerequisites and using cell phones or laptops in class. INSTRUCTOR Dr. Cheryl Moy (Kenan Labs C147E) Class meeting: Gardner (GA) 008, MWF 9:00 am – 9:50 am How to contact Professor Moy • Questions about logistics, administrative matters, and course success: Office Half-­‐Hours (Kenan C147E) M 3:00 pm – 3:30 pm W 2:00 – 2:30 pm Th 10:30 am – 11:00 am • Questions about chemistry: Studio Sessions (See Sakai for room assignments.) M 1:00 pm – 2:00 pm Tu 10:00 am – 11:00 am W 1:00 pm – 2:00 pm * Th 4:00 pm – 5:00 pm * M/Tu/W TBA Studio sessions are weekly opportunities to work problems and talk about course content. Questions about lecture material should be presented during the studio sessions. Every session within the week will be similar in that a “problem/worksheet of the week” will be provided at Studio and you need only to attend 1 session/week. *Indicates sessions lead by Peer Mentors. Email Policy: Prof. Moy has limited availability by email. Please refrain from asking questions about lecture material by email and during office hours. However, if there is a need to email Prof. Moy, please email to moy_chem262@unc.edu and include “Chem262” and a one-­‐word description in the subject line. Please keep your emails brief and direct. COURSE WEBPAGE sakai.unc.edu Check the course webpage frequently as lecture materials, practice problems, and answer keys to exams and quizzes will be posted to this webpage. COURSE FORMAT AND EVALUATION The total number of points possible for the course is 600. The following grading scale will be used. Grades for the class may be scaled up at the instructor’s discretion, but guaranteed minimum values for letter grades are listed below: Percent Score Course Grade Percent Score Course Grade 94.0 – 100.0 A 74.0 – 79.0 C 90.0 – 93.0 A-­‐ 67.0 – 73.0 % C-­‐ 84.0 – 89.0 B 55.0 – 66.0 D 80.0 – 83.0 B-­‐ < 55.0 F The following is a breakdown of how points are distributed: Exams – 300 points There will be three in-­‐class examinations, each worth 100 points. Exam #1: Friday, September 12 Exam #2: Wednesday, October 15 Exam #3: Friday, November 14 Examinations must be taken at the scheduled time unless prior arrangements are made. Arrangements must be made at least two weeks in advance. Documentation will be required for the accommodation to be granted. We do our best to grade the exams with consistency and fairness. However, we can make mistakes. If you feel that a question on a midterm exam has been graded in error, you will have one week to submit a request for a regrade. When you are submitting a regrade request, you are doing so with the understanding that the entire exam will be regraded. Note that since grading mistakes can occur in either direction, a regrade may increase or decrease your score. Final Examination – 200 points There will be a cumulative final examination worth 200 points. Final Examination is Saturday, December 6th from 8:00 – 11:00 am. Daily Work – 100 points Daily work has 3 components: 1. Weekly In-­‐class Quizzes -­‐ Quizzes will be given throughout the semester and will serve as opportunities for you to evaluate your understanding of the material and assess your study habits. Quizzes will be given during the first ten minutes of class of most Friday lectures. You must bring your clicker to class to take the quiz. All quizzes are to be worked on independently and there will be NO MAKE-­‐UP quizzes offered. See tentative course schedule for all in-­‐class quiz dates. Each quiz is worth 6 points. 2. Daily Problem Solving – Each class period you will work through several problems chosen to apply course content. Given that the question is not a part of the weekly in-­‐class quiz, you will be allowed to talk to your neighbors, use your notes, textbook, and other resources that may be useful for solving these problems. Your understanding will be assessed via clicker questions; each day of problem-­‐solving is worth 3 points. 3. Studio Attendance – As listed above, there are opportunities to attend a studio session to work in groups on and receive help on a specific problem assigned that week. For every week that you attend a session, you will receive 3 points. Summary Table Component Weekly Quizzes Daily Problem Solving Studio Attendance Min. Daily Work Points Available Max. Daily Work Points Applicable to Final Grade Each Worth 6 3 3 -­‐-­‐-­‐ -­‐-­‐-­‐ Min. # 11 28 13 -­‐-­‐-­‐ -­‐-­‐-­‐ Min. Total 66 84 39 189 100 These three components offer the opportunity to earn more points than will count towards your final score. I will offer at least 189 Daily Work points the entire semester, but you can only earn a maximum of 100 points toward your Daily Work. KEYS TO SUCCESS Practice. Practice. Practice. I cannot emphasis this enough: do as many problems as possible. I will give you a list of suggested problems for each chapter. Attempt the problems without the answer key or solution manual in front of you. Struggle with the problems. Organic chemistry is difficult, but that is because you are in the process of training yourself to reason in a way that you are not used to and it will be uncomfortable. Embrace that discomfort and you will formulate the connections and patterns that work for you. Get help as soon as possible, if you need it. Try your best to stay on top of the content. The weekly quizzes are to help you not get behind. If you do not understand something, talk to a friend/classmate outside of class or come to studio sessions. Although you need to only come to 1 studio session/week for credit, you are welcome to come to as many sessions as you would like. Stay healthy. Eat well, set aside a bit of time to de-­‐stress, and sleep. You will be able to better retain information, learn, and not fall behind if you are healthy and happy. Here is a list of resources for your information: • Resource center in Kenan 143. Hours: M-­‐Th 2:00 pm – 8:00 pm • Peer Tutoring Program in Dey Hall. Juniors and senior students offer one-­‐on-­‐one tutoring. Times and Days TBA. • The Learning Center. Free tutoring by appointment, signup at http://learningcenter.unc.edu/services/Math%and Science/tutoring-­‐for-­‐math-­‐and-­‐sciences TENTATIVE SCHEDULE Day Date Assessment Chapter Topic W 8/20 1 F 8/22 2 Quiz 1 n/a 15 & 7 M 8/25 3 W 8/27 4 Review 261 Aromaticity Diels Alder F 8/29 5 Quiz 2 M Lecture 9/1 Labor Day Labor Day W 9/3 6 F 9/5 7 Quiz 3 M 9/8 8 W 9/10 9 F 9/12 Exam 1 Exam 1 9/15 10 W 9/17 11 F 9/19 12 Quiz 4 M 9/22 13 W 9/24 14 F 9/26 15 Quiz 5 M 9/29 16 W 10/1 17 F 10/3 18 Quiz 6 M 10/6 19 W 10/8 20 F 10/10 21 Quiz 7 M 10/13 22 W 10/15 Exam 2 Exam 2 F 10/17 Fall Break Fall Break 10/20 23 W 10/22 24 F 10/24 25 Quiz 8 M 10/27 26 W 10/29 27 F 10/31 28 Quiz 9 M 11/3 29 W 11/5 30 F 11/7 31 Quiz 10 M 11/10 32 W 11/12 33 F 11/14 Exam 3 Exam 3 NMR 11 Organometallics M M 14 17 Class I Carbonyls 18 Class II Carbonyls 19 Class III Carbonyls 20 Redox rxns 16 Electrophilic Aromatic Substitution 21 Amines M 11/17 34 W 11/19 35 F 11/21 36 Quiz 11 M 11/24 37 W 11/26 Thanksgiving Break Thanksgiving Break F 11/28 Thanksgiving Break Thanksgiving Break M 12/1 38 W 12/3 39 SAT 12/6 Final Exam Final Exam 22 Carbohydrates 23 Amino Acids/Peptides DISCLAIMER Professor Moy reserves the right to make changes to the syllabus, including project due dates and test dates (excluding the officially scheduled final examination), when unforeseen circumstances occur. These changes will be announced as early as possible so that students can adjust their schedules.