5 E’s Lesson Planning Template Lesson: #1 #3 Draft #3 Final (circle or highlight appropriate lesson) Name: Loren Schwinge Course/ Grade Level: 8th/ 9th Standard(s) Addressed: Grade 8, 2C and 2D Genetics Students know that an inherited trait can be determined by one or more genes, and that plants and animal cells contain many thousands of different genes and typically have two copies of every gene. The two copies (or alleles) of the gene may or may not be identical, and one may be dominant in determining the phenotype while the other is recessive. Lesson Objective: Students will be able to understand that inherited traits are determined by genes, and that there are many types of genes that code for many different things by working through punnett squares and by doing monohybrid and dihybrid crosses to show how dominance and recessiveness work. Materials Used: • • • • Blank piece of paper White board markers A coin (any type) and a di (for randomness selection) Pencil Classroom Management: • State expectations of the class (that they should be quiet, attentive, raise their hand if they have a question, and participate if they are asked to work out a problem on their paper) • Will use popsicle sticks with the students names on them for random selection of answers • Students will break into pairs for the monster genetics portion ENGAGE: Connect to Prior Knowledge and Experience, Create Emotionally Safe Learning Environment, Preview New Vocabulary Estimated time: 10 minutes Description of Engage: Ask the students how many of them can roll their tongues. Note that in a large class at least some students should not be able to do this. Ask students why they think this might be. Then ask how many have dark eyes. After counting the hands raised, then ask how many have light eyes. Since brown eyes are dominant to blue or green eyes, there should be more dark eyed students. Ask the students what may be the reason for more dark eyed people than light eyed people. Then begin to explain that these types of genetic inheritance are called alleles, and then explain that some alleles are dominant and that others are recessive (brown eyes “BB/Bb” versus blue eyes “bb”). Students get one allele from each of their parents. If a student has hazel eyes ask what color their parents eyes are. Mention that eye color can sometimes demonstrate incomplete dominance. After, bring up the idea of phenotype and genotype, and how they can actually be different. Go back to the tongue rolling idea Teacher’s Role Teacher Questions Students’ Role - Keep count of the students who answer dark and light eyes - Encourage the students to come up with reasons for the number differences - Then have them go through and hypothesize what their genotypes might be as opposed to their phenotypes - “Why do you think more students have dark colored eyes than light?” - Answer polling questions of teacher - “What color eyes do your parents have?” - Come up with hypotheses as to why there would be eye color differences - “How many have eyes that are different than their parents? How many of your eyes are the same? How many are a mixture of both?” - Make comparisons as to which ones are similar with their parents - “Are any of your eyes a mixture of both parents?” - “How might your phenotype for this trait differ from your genotype?” - Come up with the genotypes for the recessive traits that they have, as well as the dominant traits (since the dominant trait can be homozygous or heterozygous there should be more than one option) - “How is it possible that my sister cannot role her tongue but both my parents and I can?” EXPLORE: Hands-On Learning, Contextualize Language, Use of Scaffolding (Graphic Organizers, Thinking Maps, Cooperative Learning), Use of Multiple Intelligences, Check for Understanding Estimated time: 20 minutes Description of Explore: Baby Monsters! Each student will break up into pairs of two. Students will all be given a monster family portrait worksheet/packet. The teacher and students will work through several practice questions to prepare to make their own monster family tree. Students will then determine the phenotype and genotype of their own baby monsters. The worksheet will have spaces for the students to write the genotypes of their monsters and draw pictures of each monster. Teacher’s Role Teacher Questions Students’ Role - Prepare worksheets with parent monsters and parent monster genotypes. - “How would I set up my punnet square to determine this trait?” - Work in a group to make punnet squares for each of your baby monsters. - Do an example of how to do monohybrid and dihybrid crosses for each trait and role dice/flip a coin to select a genotype and determine one baby monsters phenotype. In other words fill out worksheet page 2 with students. Make sure to ask students how they would do it first, don't just spoon feed the answers. - “For this type of cross (monohybrid or dihybrid) would you flip a coin or role dice to pick a genotype?” - Students should make at least one baby monster for each person in the group. - Students should assist each other and check each other's work. - Students should draw their baby monsters on the worksheet to show the monsters phenotype. - Walk around and assist students as necessary EXPLAIN: Listening, Speaking, Reading, and Writing to Communicate Conceptual Understanding Estimated time: 10 minutes Description of Explain: Have two or three volunteers go up and present their monster family portrait. Ask the class to list all the possible genotypes for one of the baby monsters phenotypes. Ask a student to demonstrate how they came up with their answer. Poll students: how many of your monster siblings look the same? Different? Ask students what challenges they had Teacher’s Role Teacher Questions Students’ Role - Present their work. - “Who wants to show the - Facilitate the class. class their monster family - Analyze other student's work to -­‐ Place student's family trees up portrait?” demonstrate understanding. on the ELMO for the class to Explain how they came to their “Can anyone give me an see. conclusions. example of one of the genotypes that would result in this monsters phenotype? How do you know this? Who else can give me a genotype? Can you explain how you know this?” - “Who can demonstrate how they determined the possible genotypes for their monsters teeth? How about for their monsters horns?” - “How many of your monster siblings look the same?” - “If they look different how might the parents genotype have contributed to this?” EVALUATE: Thinking Maps, Summarize Lesson and Review Vocabulary, Variety of Assessment Tools, Games to Show Understanding Estimated time: 10 minutes Description of Evaluate: Have the students complete three dihybrid crosses (GGTTx x ggtt, GgTt x GgTt, GgTt x ggtt) through the use of a punnett square and state their results (for example, if using pea plants: how many green as opposed to yellow, how many short as compared to tall, etc.) Teacher’s Role Teacher Questions Students’ Role - Put up a picture of the several different possible pea plant phenotypes. - “How many of each phenotype did you find?” - Complete the punnet square with the crosses presented - “Can someone come up and - Put the dihybrid cross on the write all the possible board so the students can see it genotypes for this pea plant?” clearly, and write the questions (Have a different student you want found below (for come up and write up example, how many green, how genotypes under one of the many tall, etc.) pea plant phenotype pictures until all possible genotypes - Ask questions that would are listed underneath the prompt the students to notice pictures.) dominant and recessive genes - “What caused the plants to be mostly green and tall?” - “What caused the heterozygous plants to look the way they did?” - “What evidence supports the presence of dominant and recessive genes?” - Ask their elbow partner if they get stuck EXTEND: Group Projects, Plays, Murals, Songs, Connections to Real World, Connections to Other Curricular Areas Estimated Time: 10 minutes (or homework) Description of Extend: Give students a pedigree that has to do with sex-linked chromosomes and see if students can fill in the genotypes based on the pedigrees phenotypes. Use this pedigree for Hemophilia (http://www.sciencecases.org/hemo/hemo.asp) in Queen Victoria's family. Explain to students that sometimes genes are only carried on one sex chromosome or the other. Put up the male and female genotypes and give them a hint before they start like: if you are a male, does it matter for your phenotype if an X carried trait is recessive or dominant? Sounds cool Teacher’s Role - Show students a simple pedigree used to determine genotypes using a family history of phenotypes (for tongue rolling for instance). - Tell students, that genes can also confer genetic diseases along with other more visible traits. - Next give students the pedigree of a family with Hemophilia. Explain that hemophilia is a disease that prevents normal bloodclotting. - Give students time to try and figure out the pedigree. - If students cannot figure it out (they may not be able to) tell them about how the gene for colorblindness is carried on the X chromosome to prompt them to consider hemophilia as a sex-linked disease. Teacher Questions Students’ Role - Are all phenotypes physical traits? Or can your genes confer other traits/conditions? - Try to solve the pedigree and determine the genotypes of individuals using a family history of phenotypes. - Why would a scientist or doctor use a pedigree? - Are males more at risk for sex-linked genetic diseases than females? Why? - Who can tell me the genotype of this person? How do you know? Baby Monsters! Complete your monster family tree by completing punnet squares to determine the possible genotypes of the baby monsters. Show your work! Your punnet squares must be turned in with your monster family tree. Questions: ((Note: Questions 1-­‐5 will be done together as a class)) 1) Draw the phenotype corresponding to the first baby monsters genotype 2) Considering the parent monster’s genotypes, use punnet squares to determine the possible genotypes for the baby monsters teeth. Use dice or a coin to randomly select a tooth genotype and draw the appropriate phenotype. 3) Write a possible genotype that could account for this baby monsters phenotype. Don’t forget to consider her parent’s genotypes! 4) Considering the parent monster’s genotypes, use punnet squares to determine the possible genotypes for the baby monsters horns. Use dice or a coin to randomly select a tooth genotype and draw the appropriate phenotype. Hint: two genes contribute to the horn genotype (color and shape) so a monohybrid cross cannot be used. 5) Based on the coloration of the parent and baby monsters, what type of dominance do you think the alleles for color have? 6) Now that you have had some practice, can you use punnet squares and dice to randomly determine the genotype and phenotype of the baby monsters on the third page? KEY Color R = red r = blue Teeth F = flat f = pointy Horns T = triangular t = zigzag Horn Color G = green g = yellow Sex XX = female XY = male Class Monster Family Tree Meet the parents: Papa Monster RR Ff Tgtg XY The children: 1 2 Rr ff tgtg XY rr ff tgtg XX 3 Rr Ff ???? XX Rr ?? Tgtg XX Mama Monster 4 Group Monster Family Tree Meet the parents: Papa Monster Mama Monster Rr Ff Tgtg XY The children: 1 2 Rr ff tGtg XX 3 4 Rr ff tgtG XY