duke urology update

advertisement
DUKE UROLOGY UPDATE
I
DUKE
UROLOGY
A Division
of the
Department
of Surgery
INSIDE:
Faculty News ......
New Faculty........
Faculty Awards ...
Clinical Section ...
Resident Section .
Research Section .
Recent Significant
Papers................
2
3
3
4
5
7
8
Alumni Section ....10
Continuing
Medical Education
Section ...............11
Duke Urologic
Assembly
Symposium .........12
Fall 2013
WELCOME
t has been a busy summer in Durham with the opening of the new
Duke Medicine Pavilion in July. This major expansion of Duke University Hospital includes 16 operating suites and 160 critical care
beds that greatly expands our ability to provide enhanced care for our
patients. We, also, welcomed two new faculty members: Dr. Chuck
Scales, who recently finished a Robert Wood Johnson Foundation Clinical
Scholars Fellowship in Health Sciences Research at UCLA and Dr. Sam
Eaton, who recently completed an Endo-urology fellowship at Northwestern University.
We had an extremely impressive showing at this year’s AUA meeting
in San Diego. In fact, our Duke Urology alumni reception held on Saturday evening May 4, 2013 broke all attendance records. It was wonderful
Glenn M. Preminger, MD
Chief of the Division of Urology to see all of our DYSURICs and friends from across the country and
around the world. We anticipate an equally impressive showing at the
upcoming AUA meeting in Orlando in 2014.
This past June, we graduated three outstanding chief residents, John Mancini, Suzanne Stewart
and Brian Whitley. I had the opportunity to see all three at Brian’s wedding in Durham. John, Suzanne
and Brian all appear to be enjoying their current positions. We are extremely proud of these individuals
and know that they will stay in contact with the program.
We are especially proud of our residents who have achieved major accomplishments over the past
few months. Tara Ortiz received a Urology Care Foundation 2013 Residency Research Award at the AUA
meeting in San Diego and Zarine Balsara represented Duke Urology on the Southeastern Section team
that won the Annual Residency Bowl during the AUA. There were also
major accomplishments for our faculty. Brant Inman was named the Cary
“We are especially
Robertson Assistant Professor of Urology in June. In addition, John
Wiener was named to the American Board of Urology Examination Comexcited about our
mittee to write the questions for the Urology Board Exams, annual resi- upcoming 46th annual
dent in-service exams, the SASP program, and Pediatric Urology
Duke Urologic
Certification Examination.
Assembly
Our newsletter includes updates on our progress here at Duke and
symposium,
which
in our Duke Urology of Raleigh practice. In addition, Sherry Ross provides
a wonderful update of our Pediatric Urology Research Program. Finally,
will be held in
John Wiener provides an update on Duke Urology CME activities. We are
Pinehurst in early
especially excited about our upcoming 46th annual Duke Urologic AsApril, 2014.”
sembly symposium, which will be held in Pinehurst in early April, 2014.
We would love to see as many DYSURIC’s as possible attending this meeting, as we will have a special dinner for our DYSURIA members.
I believe that our alumni are our most loyal supporters. We value your ideas, feedback and contributions. With industry funding virtually at a standstill, it is becoming much more difficult to support
the educational activities of our residency program. Never has it been more critical that we receive support from our alumni for the continued success of Duke Urology. I would urge you to consider making
a contribution to the DYSURIA society, which will go 100% to help support urology resident training at
Duke. As we strive to keep our program as one of the elite training programs in the country, your support
of resident education becomes even more critical.
Please consider making a year-end gift to DYSURIA. As always, we welcome you back to Durham
for a visit so we can show you how much we have grown both within Duke Urology and at the Duke
University Medical Center.
All the best for a wonderful holiday season,
Glenn
FACULTY NEWS
FEATURED FACULTY:
Thomas Polascik, MD
Dr. Polascik, who recently returned from
the 6th International Symposium for Imaging
and Focal Therapy in Prostate Cancer, has been
actively engaged in this innovative treatment
approach over the past 10 years.
“Focal therapy fundamentally changes
the approach to how prostate cancer is diag-
Cary N Robertson, MD,
Assistant Professorship
Announcement
Brant A. Inman, MD,
MS, FRCSC
Theodore N. Pappas, MD, Distinguished
Professor of Surgical Innovation, Interim Chair,
Department of Surgery is pleased to announce that Brant A. Inman, MD, MS, FRCSC
2
nosed and managed,” Thomas Polascik, Duke
Urology.
Focal therapy is an emerging technical approach that uses three dimensional imaging
and targeted treatment to spare the prostate
gland, and preserve the urinary and sexual
function of the patient. Advances in both imaging and therapeutic technologies have enabled urologists to approach treatment in an
entirely new way. New multi-parametric MRI
technology can locate and target prostate cancer lesions more precisely than ever before, and
new therapeutic devices such as cryotherapy,
irreversible electroporation, and high intensity
frequency ultrasound (HIFU) are in various
stages of clinical trial and development. These
new imaging technologies and therapeutic devices may significantly reduce the role of traditional surgical extirpation or radiation therapy.
Dr. Polascik is involved in several research
studies and clinical trials examining new technological releases. He is a firm believer that
new technologies will improve patient outcomes, and safety, and lead not only to patient
living longer after prostate cancer, but with a
better quality of life.
Dr. Polascik has been at Duke since 1998.
He received his MD, at the University of
Chicago in 1991, and completed his Urology
Residency at Johns Hopkins in 1997. He has
risen to the rank of Professor of Urology, and
is currently the Director of Urologic Oncology
and Director of the Genitourinary Focal Therapy Fellowship Program at Duke. He has published over 200 manuscripts on minimally
invasive therapy, and oncologic urology, and is
considered an international thought leader in
focal therapy of prostate and renal cancers.
Dr. Polascik is, also, an experienced practitioner of robotic surgery and is using this new
minimally invasive approach to deliver highquality, more precise treatments to his patients.
Using the da Vinci robotic system, Dr. Polascik
provides nerve-sparing robotic prostatectomy
to his patients, and has recently begun using a
new imaging technology to perform partial
nephrectomy for kidney cancer patients. The
new imaging technology trademarked FireFly®,
by Intuitive Surgical, Inc. is an imaging system
that allows surgeons to locate cancerous lesions with more precision. The urologist injects
an indocyanine fluorescent dye into the patient, which is then agitated with a laser, and
glows fluorescent green.
“The robotic system gives me a greater degree of articulation than traditional laparoscopy, and makes suturing much easier
and more precise,” Thomas Polascik, Professor of Surgery Duke Urology.
has been awarded the Cary N. Robertson,
MD, Assistant Professorship
Brant A. Inman, MD, MS, FRCSC, Assistant Professor, Division of Urology, has been
awarded the Cary N. Robertson, MD, Assistant Professorship. This Duke Medicine endowed professorship honors our most
distinguished physician-scientists who have
demonstrated extraordinary academic excellence in advancing medical science and
human health.
Dr. Inman joined Duke in 2008 and is currently Vice Chief of Urology Research, Director
of Clinical Trials for the Division of Urology,
and a member of the Duke Institutional Review Board. His area of clinical expertise is the
surgical treatment of genitourinary cancers,
and in particular bladder, kidney, penile, and
testicular cancer. From a research standpoint,
Dr. Inman’s laboratory is focused on developing novel therapies and diagnostic tests for
bladder cancer as well as exploring the immunologic aspects of genitourinary cancers.
Nationally, Dr. Inman is a core member of
the bladder and penile cancer panels of the
National Comprehensive Cancer Network
(NCCN). He is also on the Board of Directors
of the Society of Urological Oncology Clinical
Trials Committee and a member of the Bladder Cancer Advocacy Network (BCAN). He
has consulted for Blue Cross Blue Shield of
North Carolina and for the U.S. Environmental
Protection Agency on issues pertaining to urologic health. Internationally, Dr. Inman currently serves as consulting editor for the
Journal of European Urology.
Dr. Inman received his undergraduate
and medical degrees from the University of Alberta (Edmonton, Canada). He then completed his urology residency at Laval University
(Québec, Canada) and his urologic oncology
fellowship at the Mayo Clinic (Rochester, Minnesota).
The Cary N Robertson Assistant Professorship was made possible by donations from
Earnest and Mildred Mario, Stanley P. Porter,
Ella Ann L. and Frank B. Holding Foundation,
R.A Bryan Foundation, Sam and Nancy Chestnut and the Samuel L. Phillips Foundation.
This fund commemorates the extraordinary
contributions of current Duke Associate Professor, Dr. Cary N. Robertson, who continues
to serve Duke as a teacher and scientist, advancing the field of urology.
•
DUKE UROLOGY UPDATE
•
FALL 2013
FACULTY AWARDS
NEW FACULTY
Charles Scales, Jr, MD
Sam Eaton, MD
Dr. Scales received his medical degree
from Duke University in 2004 and stayed at
Duke to complete both a urology residency
in 2011 and a fellowship in endo-urology in
2012. He completed the Robert Wood Johnson Foundation Clinical Scholars Program at
the University of California, Los Angeles in
2013. His clinical interests include medical
and surgical management of kidney stone
disease, shock wave lithotripsy, medical and
minimally-invasive management of benign
prostatic hyperplasia, and endoscopic management of urinary-tract obstruction. Dr.
Scales returns to Duke as Assistant Professor
of Urology and will be conducting his clinical
practice at Duke University Hospital.
Dr. Eaton received his medical degree
from Columbia University College of Physicians and Surgeons in 2003. Following completion of his urology residency at Boston
University in 2011, he completed a 2 year
endo-urology fellowship at Northwestern University in Chicago that focused on both advanced stone management as well as
laparoscopic and robotic surgery. His clinical
interests include stone disease (including both
medical and surgical management), prostate
cancer (including robot-assisted prostatectomy), kidney cancer (focusing on minimally
invasive and renal sparing techniques including robotic partial nephrectomy), upper tract
urothelial cancer (including endoscopic management and robotic assisted nephroureterectomy), upper tract obstruction (endoscopic
and laparoscopic/robotic management of UPJ
obstruction and ureteral stricture disease), as
well as general urology. Dr. Eaton joins the faculty as Assistant Professor of Urology and will
practice at Duke Urology of Raleigh.
George D. Webster, MB, FRCS was honored by the Society of Urodynamics, Female
Pelvic Medicine and Urogenital Reconstruction for his leadership in fellowship training
for the specialty of Female Pelvic Medicine
and Reconstructive Surgery. Dr. Webster,
along with Drs. Jerry Blaivis, Ed McGuire and
Shlomo Raz were recognized as pioneers in
the development of this specialty at a dinner
and tribute entitled, “Standing on the Shoulders of Giants” in San Diego, CA, May 4,
2013.
Edward N.
Rampersaud Jr.,
MD was selected
to serve on the
NCCN Kidney
Cancer Guidelines
panel.
Pei Zhong, Ph.D.
was endowed as
Anderson-Rupp
Professor of Mechanical Engineering and Materials
Science from July
1, 2013 to June
30, 2018.
Glenn M. Preminger, MD received the prestigious
St. Paul’s Medal from the British Association of
Urological Surgeons for contributions to the field
of Urology and was honored at the annual meeting in Manchester, England on June 20, 2013.
DUKE UROLOGY UPDATE
•
FALL 2013
•
3
CLINICAL SECTION
Community
Urology: Using
Webinars for
Patient Education
"The internet has
changed how
patients learn and
cope with their
disease. For
physicians, the
internet provides
an opportunity
to present
wide-ranging
and current
information in
a variety of
teaching formats.
The internet eliminates many of the
traditional barriers to patient education and
empowers patients with 24 hour access to
high-quality, patient-centered resources,"
Aaron Lentz MD, Duke Urology of Raleigh.
Delivering care to the patients of Wake
County has given Duke Urologists a unique
opportunity to our bring cutting edge therapies to a new patient population, and the
staff at Duke Raleigh Hospital provide outstanding care and service to our patients”
Cary N. Robertson, Professor of Urology
About Duke Urology
of Raleigh
In conjunction with Duke Raleigh Hospital, Dr. Lentz and the team of urologists at
Duke Urology of Raleigh have begun providing patient education services by offering interactive webinars for patient education. The
webinars are live presentations accessible to
the public through the Duke Raleigh website,
and allow for “real-time” question and answer sessions with our physicians. After a focused presentation, patients can submit
questions via text message, instant message,
or Twitter. The topics presented to date have
focused on male-wellness including erectile
dysfunction and low testosterone.
In the future, the webinars will be expanded to cover many more urologic conditions. After conclusion of the live session,
each webinar is uploaded to the Internet and
can be accessed through YouTube
(http://www.youtube.com/user/DukeRaleighNews) or the Duke Raleigh Hospital website. We are very proud of this
outreach project and anticipate partnering
with the hospital for additional patient service opportunities.
4
Duke Urology of Raleigh was established in 2010 on the Duke Raleigh Hospital
Campus, and provides both inpatient and
outpatient care to the Wake County community. The hospital has welcomed the services
and expertise of Duke Urologists, and we
provide a full service of oncological, reconstructive and general urological services
using the latest advances in minimally invasive and robotic techniques.
Location: 2480 Wake Forest Road,
Raleigh, NC 27609
Urologic Cancer
Survivorship Clinic
The Urologic Cancer Survivorship Clinic
is designed to meet the quality-of-life needs
of the growing number of cancer survivors.
Minimally invasive treatments, for example,
can help patients with leakage of urine and
•
DUKE UROLOGY UPDATE
•
voiding dysfunction. Infertility can be addressed as well, with many new and effective
therapies. The Survivorship Team is actively
involved in research to assess new treatments – such as the male sling for incontinence (the procedure involves placement of
a synthetic mesh in the groin to elevate the
urethra and alter its position) – and outcomes studies that evaluate patient perceptions of survivorship before and after
treatment in the clinic.
Duke Urology is the first program in the
country to offer specialized training in the
treatment of conditions that affect cancer
survivors’ quality of life. The Genitourinary
Cancer Survivorship Fellowship at Duke University and the Durham Veterans Administration Medical Center is a one-year program
that offers the fellow an opportunity to become proficient in the evaluation and management of all morbidities suffered by
patients who have undergone treatment for
urologic and pelvic malignancies. This program focuses on managing the genitourinary
concerns and complications of patients who
have undergone treatment for genitourinary,
pelvic and other malignancies.
The operative scope of the fellowship includes intra-abdominal and pelvic reconstruction, urinary stricture and fistula disease,
erectile dysfunction, urinary incontinence
and complex voiding dysfunction as a result
of prior cancer treatment. Fellows also participate in multidisciplinary projects including
urology, colorectal surgery, gynecology, radiation and medical oncology that attune
them to the continuum of care for this group
of patients. A structured training program in
FALL 2013
cancer survivorship confers a unique set of
medical and surgical skills to urologists who
want to care for the burgeoning number of
cancer survivors, while improving our
patient care and research opportunities at
the same time.
“We are really a
leader in this area,”
says Drew Peterson
(Clinic Medical Director), acknowledging an
upcoming American
College of Surgeons
Commission on Cancer
(CoC) requirement for
all accredited programs
to offer a survivorship
program by 2015.
Andrew C.
Peterson, MD
Men’s Health Day
Duke Urologist’s participated in the Annual Duke Cancer Institute’s Men’s Health
Day held in Durham on September 22 and
23, 2013. The event was held at Duke University Hospital and Lincoln Community
Health Center. Duke Urologic Oncology faculty, Lincoln Community Health providers,
Durham Diabetes Coalition and Healing with
CAARE Inc. offered advice on prostate cancer risk assessment (based on the latest AUA
recommendations), diabetes screening,
blood pressure checks, and body mass index
(BMI) screening. 19 faculty and staff for Urology attended the event and provided medical advice and screening services to the
conference attendees.
“In general, many men do not visit a
doctor regularly”, says Judd Moul, MD, Duke
Urologist and James H Semans Professor of
Surgery, and this event brought many men
in for a more comprehensive health assessment. Moul says the teams used the new
American Urologic Association (AUA)
Judd Moul, MD
prostate early detection guidelines to inform
men about their current and future risk for
prostate cancer while doing this in the context of their overall health status.
The Duke Urologic Oncology team performs its clinical work as a core part of the
Duke Cancer Institute, in the newly opened
Duke Cancer Center which has created a
multi-disciplinary working environment were
urologists, medical oncologists, and radiation
oncologists collaborate to provide the best
care and treatment for cancer patients.
RESIDENT SECTION
Resident Spotlight:
Urology Care
Foundation Award
be developed which will
substantially improve patient care
in this population.
“I am extremely proud that
the research that we are
conducting here at Duke has been
recognized by the AUA, and that
Tara K. Ortiz, MD received a
the hard-work and dedication that
prestigious Urology Care Foundation
Tara has devoted to this project
Residency Research Award at the
has paid off. Dr. Seed and I are
AUA annual meeting held in San
looking forward to mentoring her
Diego, CA, May 4-8, 2013.
through her research year
Dr. Ortiz, a third year Duke Urology
experience, as she completes this
Resident, is spending her research year
project,” Sherry Ross, MD Pediatric
Tara Ortiz, MD
in basic science working under the
Urology.
mentorship of Sherry Ross, MD
Tara’s research project titled:
(Pediatric Urology) and Patrick Seed, MD PhD “The Role of Type I Pili in the Adherence and
(Pediatrics). She is utilizing this teams novel urinary Invasion of Bladder Epithelium in a spinal Cord
tract infection-spinal cord injury rat model to better injured rat model” was awarded the Russell Scott
understand the increased susceptibility of the Jr. Urology Research Award. The Urology Care
neurogenic bladder to urinary tract infections, a Foundation is the official foundation of the
leading cause of morbidity and mortality in patients American Urological Association and offers these
with a neurogenic bladder due to neurological awards to only four residents per year. Other award
injury or abnormalities such as Spina Bifida. By recipients included residents from Columbia,
better understanding the mechanisms that result Loyola and Stanford.
in increased infections of the neurogenic bladder,
“Tara’s recognition is a testament to the
improved treatment and preventive therapies can quality of faculty mentorship and institutional
DUKE UROLOGY UPDATE
•
FALL 2013
• 5
support that our residents receive during their
research year experience here at Duke. We are
proud to be supporting the development of the
future generation of basic science researchers in
Urology,” Steve Freedland, Urology Research
Residency Director.
About Urology Resident
Research at Duke
All residents in Urology at Duke spend
a full year in dedicated academic research.
This has been a long tradition at Duke and
we are now one of only a few programs in
the country to offer such an experience. We
firmly believe that this year is invaluable in
training the future urological leaders of tomorrow. Whether our graduates will pursue
academic careers or full-time clinical practice,
they need to be experts in understanding the
literature and how to interpret new scientific
discoveries as they apply to their practice.
What better way to understand the literature
.
Continued on next page
RESIDENT Con’t.
than to be a contributor? In addition, our residents gain a deep understanding of statistics
– the language of how to communicate scientific findings. This year also provides valuable time for our residents to reflect on their
careers and help formulate their career plans.
Due in large part to this dedicated research
year, Duke Urology has produced many leaders in urology from department chairs, to
leading academicians, to premier clinicians.
The dedicated research year is an important
tradition for Duke Urology and one that we
are extremely proud of.
2013 Incoming
Residents
(Class of 2019)
Bryce A Allio, MD
Medical School:
New York – University of Rochester
Eugene B. Cone, MD
Medical School: Brown University
Left to Right: Peterson, Balsara, Assimos,
Preminger
2013 Graduating
Residents
Duke hosts North
Carolina Urology
Resident Symposium
The Grandover Residency Retreat is an
annual event where the three North Carolina
urology programs (Duke, UNC and Wake Forest) meet for a research and debate competition. This is the 13th year of the event and
was attended by 28 residents and 27 faculty.
A nationally renowned visiting professor is
brought in to give an educational lecture during the day’s events. This year, Dr. James Eastham, Chief of Urology at Memorial
Sloan-Kettering gave our keynote lecture on
"Clinically Localized Prostate Cancer".
“This event gives residents the opportunity to network with their peers, and is an invaluable learning experience. We hope to
continue being able to fund this and other
educational opportunities for our residents in
the future,” Michael Ferrandino, MD, Associate Program Director, Duke Urology Residency Program.
Duke was represented well in the research and debate competition. Dr. Nicholas
Kuntz took first place for his research presentation titled "Striking Dose and Time Dependency of Radiation Cystitis in the Rat:
Repeat Cystometric Evaluation with Saline
Alone and Potassium Chloride Challenge".
Our residents, Rajeev Chaudry MD and
Michael Granieri, MD, won their debates,
with Duke bringing home 2 out of a possible
4 awards in the debate competition.
6
Resident Honors
Zarine R. Balsara, MD, PhD was a
member
of the Southeastern Section team
John G. Mancini, MD – Class of 2013
that
won
the American Urological AssociaPrivate Practice: United States Armed Forces
tion Residency Bowl Competition at the AUA
annual meeting held in San Diego, CA, May
Suzanne B Stewart – Class of 2013
4-8,
2013.
Uro-Oncology Fellowship – Mayo Clinic, MinTara K. Ortiz, MD received a Urology
nesota
Care Foundation 2013 Residency Research
Award at the AUA annual meeting held in
Brian M Whitley – Class of 2013
San
Diego, CA, May 4-8, 2013.
Private Practice: Sanford, North Carolina
Tara K. Ortiz, MD was selected as a
2014 Feagin Leadership Scholar on July 29,
2013. This program gives scholars an opportunity to develop and apply their leadership
skills to the Duke medical community and beyond.
Michael A. Granieri, MD and Rajeev
Chaudry, MD were winners for their urologic debates at the Annual North Carolina
Urology Resident Symposium (“Grandover”)
held in Greensboro, NC, September 7, 2013.
Nicholas J. Kuntz, MD was first place
winner for his research presentation at the
Left to Right: Mancini, Stewart, Preminger, Annual North Carolina Urology Resident Symposium (“Grandover”) held in Greensboro,
Whitley
NC, September 7, 2013.
“This past June, we graduated three outstanding chief residents, John Mancini,
Suzanne Stewart and Brian Whitely. I just had
the opportunity to see all three at Brian’s wedding in Durham last month. John (Military
Urology practice in Colorado), Suzanne (SUO
Fellowship, Mayo Clinic, Rochester, MN) and
Brian (Group Practice, Sanford, NC) all appear
to be enjoying their current positions. We are
extremely proud of these individuals and
know that they will continue to support Duke
Urology,” Glen Preminger, Division Chief,
Duke Urology.
•
DUKE UROLOGY UPDATE
•
FALL 2013
RESEARCH SECTION
The Emergence of
Health Services
Research
Q
A
Health Service Research is an emerging area; could you explain the importance of this type of investigation
to the future of the field?
Health services research, also known
as population health science, focuses
on four key aspects of health care: access to care, understanding care delivery, the
financing of patient care, and patient outcomes. The Institute of Medicine has noted
Interview with
that important opportunities to improve the
Chuck Scales
quality and safety of patient care exist across
all medical specialties. Health services research provides the scientific underpinning to
identify opportunities to improve quality and
safety, design systems to deliver effective, paWelcome back to Duke Campus, tient-centered care, and rigorously evaluate
how does it feel to be back in North innovative methods of patient care.
Carolina?
Q
A
It is great to be back in North CarWhat specific areas of research are
olina. My wife and I are very excited
you planning to study?
to return to Durham, which continues to grow and be a great place to raise a
I am particularly interested in assessfamily. It is also a real privilege to join the facing the quality of urologic care delivulty at Duke, where I was a medical student
ery and designing tools or
and a resident.
interventions to improve the quality of treatment for patients with both benign and malignant urologic conditions. Current projects
You spent a year at UCLA as a focus on understanding care delivery for
Robert Wood Johnson Foundation older adults with overactive bladder symp/VA Clinical Scholar, how as your ex- toms, and creating decision aids to help paperience?
tients with kidney stones decide among
various treatment and prevention options.
The Clinical Scholars Program at Other efforts will focus on identifying opporUCLA was a phenomenal learning ex- tunities and methods for improving care deperience. Not only did I further de- livery for patients with oncologic
velop my research skills, but I also provided malignancies.
clinical care to underserved patients in Los
Angeles County. Training in leadership and
health policy were an integral part of the proWhy did you decide that Duke was
gram. Finally, I had the opportunity to be part
the place for you to begin this imporof the UCLA Health System team tasked with
tant work?
improving the quality of care by reducing inpatient mortality.
The rich clinical history of Duke Urology and Duke Surgery, combined
with the expertise and research infrastructure of the Duke Cancer Institute and
the Duke Clinical Research Institute made a
return to Durham very compelling. I’m excited to have the opportunity to begin my
clinical practice and research career at Duke.
Q
A
Q
A
Q
A
Pediatric Urology
Research
Research in the
section of Duke Pediatric Urology continues to move forward
and grow with exciting research in basic
science, outcomes
and clinical research.
Dr. Tara Ortiz, a 3rd
year Duke Urology
resident is spending
Sherry Ross, MD
her research year in
basic science working under the mentorship
of Dr. Sherry Ross and Dr. Patrick Seed, who
is instrumental in designing and overseeing
collaborative laboratory projects.
Dr. Ortiz is working to better understand
the mechanisms that increase susceptibility to
urinary tract infection in our novel neurogenicUTI rat model. We are eager to learn more
about these interactions since a better understanding of urinary tract infections in the neurogenic bladder will encourage the
development of preventive therapies for recurrent UTIs in this population.
Dr. Erin McNamara, a former Duke Urology chief resident who is currently a fellow of
pediatric urology at Boston Children’s Hospital,
presented the results of our project titled
“Evaluation of Cold Ischemia for Preservation
of Testicular Function during Partial Orchiectomy in the Rat Model” at the Society of Pediatric Urology national meeting in Las Vegas in
September. This study was inspired by the increased use of partial orchiectomy in children
with benign appearing testicular tumors and
a recent study suggesting that cold ischemia
during testicular torsion may be beneficial.
We hypothesized that cold ischemia during
partial orchiectomy in the pre-pubertal rat
would improve serum testosterone, sperm
count and histology in the post-pubertal period. Interestingly, we found that there was no
significant difference in testosterone levels or
sperm count between cold and warm ischemia but that histological parameters were
significantly worse in the cold ischemia group.
This study suggests that cold ischemia is not
beneficial during partial orchiectomy. The
Continued on next page
DUKE UROLOGY UPDATE
•
FALL 2013
•
7
.
RESEARCH Con’t.
manuscript for this study will be submitted for
consideration for publication in the Journal of
Urology.
Dr. Jonathan Routh is continuing his efforts to better understand urologic diseases
in children through outcomes research efforts. Dr. David Chu, a current Duke Urology
chief resident and Dr. Routh were invited to
present their work as a podium presentation
at the Society of Pediatric Urology national
conference. This interesting study found that
in a large, nationwide pediatric cohort, radical nephrectomy remained the most common primary surgical intervention for
pediatric renal tumors. However, over the
study period nephron sparing surgery was
consistently performed in 11% of pediatric
renal tumor cases. Importantly, they noted a
significant regional variation in the use of
nephron sparing surgery and association
with a concomitant diagnosis of renal failure/insufficiency, but not with any other clinical or socioeconomic factors. In addition, Dr.
Routh and Dr. Scott Wang, a 3rd year Urology resident, are working very hard this year
on multiple projects including a project titled
“Patterns in Emergency Care among Spina Bifida Patients: a Case-Control Study” where
they will investigate the national patterns of
emergency care among spina bifida patients
compared to non-spina bifida controls. In addition, they are utilizing the Surveillance, Epidemiology, and End Results (SEER) database
to examine nephron sparing surgery (NSS)
outcomes and factors associated with NSS
use in Wilms Tumor. Last, we are very excited
to announce that Dr. Routh was recently
awarded a K-12 grant for his work titled
“Comparative Effectiveness of Vesicoureteral
Treatments in Children”. We are very proud
of Dr. Routh and look forward to his continued research efforts that enhance our knowledge and improve the care of children in
pediatric urology.
8
RECENT
SIGNIFICANT
PAPERS
Beebe-Dimmer JL, Freedland SJ. Androgen
Deprivation Therapy: Further Confirmation of
Known Harms. BJU Int 111(5): 690-691, May
2013.
Thomas JA, Antonelli JA, Bañez LL, Hoyo C,
Grant D, Demark-Wahnefried W, Platz EA,
Gerber L, Shuler K, Eyoh E, Calloway E,
SJ. Androgenetic Alopecia at VarFreedland
Caso J, Masko EM, li JA, Poulton SH, Deious
Ages
and
Prostate Cancer Risk in an
whirst M, Pizzo SV, Freedland SJ. The Effect
Equal-Access
Multiethnic
Case-Control Series
of Carbohydrate Restriction on Prostate Canof
Veterans.
Cancer
Causes
Control 24(5):
cer Tumor Growth in a Castrate Mouse
1045-1052,
May
2013.
Xenograft Model. Prostate 73(5): 449-454,
April 2013.
Allott EH, Masko EM, Freedland SJ. Obesity
Routh JC, Grundy PE, Anderson JR, Retik AB, and Prostate Cancer: Weighing the Evidence.
Kurek KC. B7-h1 as a Biomarker for Therapy Eur Urol 63(5): 800-809, May 2013.
Failure in Patients with Favorable Histology
Wilms Tumor. J Urol 189(4): 1487-1492, Masko EM, Allott EH, Freedland SJ. The Relationship Between Nutrition and Prostate
April 2013.
Cancer: Is More Always Better? Eur Urol
Singh AA, Jones LW, Antonelli JA, Gerber L, 63(5): 810-820, May 2013.
Calloway EE, Shuler KH, Freedland SJ,
Grant DJ, Hoyo C, Bañez LL. Association Be- Fizazi KS, Higano CS, Nelson JB, Gleave M,
tween Exercise and Primary Incidence of Miller K, Morris T, Nathan FE, McIntosh S,
Prostate Cancer: Does Race Matter? Cancer Pemberton K, Moul JW. Phase III, Randomized, Placebo-Controlled Study of Docetaxel
119(7): 1338-1343, April 2013.
in Combination with Zibotentan in Patients
with
Metastatic Castration-Resistant Prostate
Tsivian M, Caso JR, Kimura M, Polascik TJ.
Cancer.
J Clin Oncol. 31(14): 1740-1747,
Renal Tumors in Solid Organ Recipients: ClinMay
2013.
ical and Pathologic Features. Urol Oncol
31(3): 255-258, April 2013.
Clark PE, Spiess PE, Agarwal N, Biagioli MC,
Abern MR, Owusu RA, Anderson MR, Ram- Eisenberger MA, Greenberg RE, Herr HW,
persaud EN, Inman BA. Perioperative Intrav- Inman BA, Kuban DA, Kuzel TM, Lele SM,
esical Chemotherapy in Non-Muscle-Invasive Michalski J, Pagliaro L, Pal SK, Patterson A,
Bladder Cancer: A Systemic Review and Plimack ER, Pohar KS, Porter MP, Richie JP,
Meta-Analysis. J Natl Compr Canc Netw. Sexton WJ, Shipley WU, Small EJ, Trump DL,
Wile G, Wilson TG, Dwyer M, Ho M. Penile
11(4): 477-484, April 2013.
Cancer: Clinical Practice Guidelines in OncolGupta RT, Kauffman CR, Polascik TJ, Taneja ogy. J Natl Compr Canc Netw. 11(5): 594SS, Rosenkrantz AB. The State of Prostate 615, May 2013.
MRI in 2013. Oncology 27(4): 262-270, April
Inman BA, Etienne W, Rubin R, Owusu RA,
2013.
Oliveira TR, Rodriques DB, Maccarini PF,
Stauffer
PR, Mashal A, Dewhirst MW. The ImWalter LC, Fung KZ, Kirby KA, Shi Y, Espalpact
of
Temperature and Urinary Condon R, O’Brien S, Freedland SJ, Powell AA,
stituents
on
Urine Viscosity and its Relevance
Hoffman RM. Five-Year Downstream Outto
Bladder
Hyperthermia
Treatment. Int J Hycomes Following Prostate-Specific Antigen
perthermia
29(3):
206-210,
May 2013.
Screening in Older Men. JAMA Intern Med.
173(10): 866-873, May 2013.
Klink JC, Tewari AK, Masko EM, Antonelli J,
Inman BA, Harrison MR, George DJ. Novel Febbo PG, Cohen P, Dewhirst MW, Pizzo SV,
Immunotherapeutic Strategies in Develop- Freedland SJ. Resveratrol Worsens Survival
ment for Renal Cell Carcinoma. Eur Urol in SCID Mice with Prostate Cancer
Xenografts in a Cell-Line Specific Manner,
63(5): 881-889, May 2013.
Through Paradoxical Effects on Oncogenic
Pathways. Prostate 73(7): 754-762, May
2013.
•
DUKE UROLOGY UPDATE
•
FALL 2013
Moreira DM, Bañez LL, Presti JC Jr, Aronson
WJ, Terris MK, Kane CJ, Terris MK, Amling
CL, Freedland SJ. High Serum Folate is Associated with Reduced Biochemical Recurrence after Radical Prostatectomy: Results
from the SEARCH Database. Int Braz J Urol
39(3): 312-319, May-June 2013.
Goldsmith ZG, Oredein-McCoy O, Gerber L,
Bañez LL, Sopko DR, Miller MJ, Preminger
GM, Lipkin ME. Emergent ureteric stent vs
percutaneous nephrostomy for obstructive
urolithiasis with sepsis: Patterns of use and
outcomes from a 15-year experience. BJU Int
112(2): E122-128, July 2013.
Solomon KR, Allott EH, Freeman MR, Freedland SJ. Re: Dysregulation of Cholesterol
Homeostasis in Human Prostate Cancer
Through Loss of ABCA1. Eur Urol 63(6):
1128-1129, June 2013.
Freedland SJ. Dietary fat and reduced
prostate cancer mortality: Does the type of Cookson MS, Roth BJ, Dahm P, Engstrom C,
fat matter? JAMA Intern Med 173(14): 1326- Freedland SJ, Hussain M, Lin DW, Lowrance
1327, July 2013.
WT, Murad MH, Oh WK, Penson DF, Kibel
AS. Castration-resistant prostate cancer:
Inman BA.Words of wisdom: Re: Final re- AUA guideline. J Urol 190(2): 429-438, Ausults of an EORTC-GU cancers group ran- gust 2013.
domized study of maintenance bacillus
Calmette-Guerin in intermediate- and high- Carter HB, Albertsen PC, Barry MJ, Etzioni R,
risk Ta, T1 papillary carcinoma of the urinary Freedland SJ, Greene KL, Holmberg L,
bladder: One-third dose versus full dose and Kantoff P, Konety BR, Murad MH, Penson DF,
1 year versus 3 years of maintenance. Eur Zietman AL. Early detection of prostate canUrol 64(1): 171-172, July 2012.
cer: AUA guideline. J Urol 190(2): 419-426,
August 2013.
Tsivian M, Abern MR, Qi P, Polascik TJ.
Short-term functional outcomes and compli- van den Bergh RC, Albertsen PC, Bangma
cations associated with transperineal tem- CH, Freedland SJ, Graefen M, Vickers A,
plate prostate mapping biopsy. Urology van der Poel HG. Timing of curative treat82(1): 166-170, July 2013.
ment for prostate cancer: A systematic review. Eur Urol 64(2): 204-215, August 2013.
Madden-Fuentes RJ, McNamara ER, Lloyd JC,
Wiener JS, Routh JC, Seed PC, Ross SS. Lotan Y, Amiel G, Boorjian SA, Clark PE,
Variation in definitions of urinary tract infec- Droller M, Gingrich JR, Guzzo TJ, Inman BA,
tions in spina bifida patients: A systematic re- Kamat AM, Karsh L, Nielsen ME, Smith ND,
view. Pediatrics 132(1): 132-139, July 2013. Shariat SF, Svatek RS, Taylor JM; Bladder Cancer Think Tank, and Bladder Cancer AdvoGbadegesin RA, Brophy PD, Adeyemo A, cacy Network. Comprehensive handbook for
Hall G, Gupta IR, Hains D, Bartkowiak B, Ra- developing a bladder cancer cystectomy
binovich CE, Chandrasekharappa S, Hom- database. Urol Oncol 31(6): 812-826, Austad A, Westreich K, Wu G, Liu Y, Holanda gust 2013.
D, Clarke J, Lavin P, Selim A, Miller S, Wiener
JS, Ross SS, Foreman J, Rotimi C, Winn MP. Balsara ZR, Ross SS, Dolber PC, Wiener
TNXB mutations can cause vesicoureteral re- JS, Tang Y, Seed PC. Enhanced susceptibilflux. J Am Soc Nephrol 24(8): 1313-1322, ity to urinary tract infection in the spinal cordJuly 2013.
injured host with neurogenic bladder. Infect
Immun 81(8): 3018-3026, August 2013.
Tsivian M, Polascik TJ. Bilateral focal ablation of prostate tissue using low-energy di- Kokorowski PJ, Routh JC, Hubert K, Graham
rect current (LEDC): A preclinical canine DA, Nelson CP. Trends in revision circumcistudy. BJU Int 112(4): 526-530, August 2013. sion at pediatric hospitals. Clin Pediatr 52(8):
699-706, August 2013.
Preminger GM. Micro-percutaneous nephrolithotomy (micro-PNL) vs retrograde
intra-renal surgery (RIRS): dealer’s choice?
The devil is in the details. BJU Int 112(3): 280281, August 2013.
Muller RL, Gerber L, Moreira DM, Andriole
G Jr, Hamilton RJ, Fleshner N, Parsons JK,
Freedland SJ. Obesity is Associated with Increased Prostate Growth and Attenuated
Prostate Volume Reduction by Dutasteride.
Eur Urol 63(6): 1115-1121, June 2013.
Moul JW. Prostate Cancer: Active Surveillance in African American Men. Nat Rev
Urol. 10(6): 311-312, June 2013.
Wang AJ, Goldsmith ZG, Wang C, Nguyen
G, Astroza GM, Neisius A, Iqbal MW, Neville
AM, Lowry C, Toncheva G, Yoshizumi TT,
Preminger GM, Ferrandino MN, Lipkin
ME. Obesity Triples the Radiation Dose of
Stone Protocol Computerized Tomography. J
Urol 189(6): 2142-2146, June 2013.
Wu C, Aronson WJ, Terris MK, Presti JC Jr.,
Amling CL, Freedland SJ. Diabetes Predicts
Metastasis after Radical Prostatectomy in
Obese Men: Results from the SEARCH Database. BJU Int. 111(8): E310-318, June 2013.
Inman BA, Abern MR. Interpreting a study
on bladder cancer screening. Eur Urol 64(1):
48-50, July 2013.
Magnon C, Hall SJ, Lin J, Xue X, Gerber L,
Freedland SJ, Frenette PS. Autonomic nerve
development contributes to prostate cancer
progression. Science 341(6142): 1236361,
July 2013.
Teeter AE, Presti JC Jr, Aronson WJ, Terris MK,
Kane CJ, Amling CL, Freedland SJ. Do
nomograms designed to predict biochemical
recurrence (BCR) do a better job of predicting more clinically relevant prostate cancer
outcomes than BCR? Urology 82(1): 53-58,
July 2013.
DUKE UROLOGY UPDATE
•
FALL 2013
•
Freedland SJ, Gerber L, Reid J, Welbourn W,
Tikishvili E, Park J, Younus A, Gutin A, Sangale Z, Lanchbury JS, Salama JK, Stone S.
Prognostic utility of cell cycle progression
score in men with prostate cancer after primary external beam radiation therapy. Int J
Radiat Oncol Biol Phys 86(5): 848-853, August 2013.
9
ALUMNI SECTION
He joined the Urology staff at Duke University Medical Center in 1965, became Assistant Professor in 1966, Associate Professor in
1969 and Professor in 1972. He has had active reserve duty entering as Captain in 1961
The Duke Youthful Society of Urology and exiting as Lieutenant Colonel in 1971.
Residents Interested in Advancement (DYAfter his retirement in 2002, Dr. AnderSURIA) was established in 1966 and is the of- son assumed the role of resident mentor at
ficial alumni association of Duke Urology. the Durham VA Hospital where he continues
DYSURIA currently has over 295 active to teach and advise residents two days a
alumni and honorary members and is a key week. To those of us at Duke, Everett is best
contributor to the success of the Duke Urol- known for his teaching and patient care skills,
ogy Residency Program
as well as his wonderful sense of humor.
“The pressures of modern healthcare
economics on educational funding, has
made it challenging for academic programs
to continue to find the financial resources to
enrich the resident educational experience,”
Drew Peterson, Program Director, Duke Urology Residency Program.
The E. Everett Anderson Education Fund
will be funded by an annual gift giving campaign that we are asking our alumni to support.
Reinvigoration of the
DYSURIA Community
The Duke Urology Residency Program
has been training residents since 1966 and
has graduated more than 100 leaders in the
field. The proud legacy of the Duke program
is the success of its graduates and their contributions to the lives of patients with urologIt is with the greatest of gratitude that ical diseases across the country. The current
we are proud to announce the E. Everett reputation and success of the Duke Urology
Anderson Education Fund, a new fundraising Residency Program is the result of the efforts
initiative to honor the educational legacy of all graduates of the program, who have
cultivated by Dr. Anderson in his more than helped shape the program and through their
48 years of dedicated service to Duke individual achievements continue to generUniversity. This new fund will be used to ate a source of pride for the Program.
support the educational needs of the
The modern pressures of clinical pracUrology Residency Program.
tice, education and research make it chal“Everett has been an integral fixture in lenging for us all to come together as a
Duke Urology for over 40 years and he con- community, and as a result we are announctinues to educate our medical students, resi- ing a new structure for the DYSURIA group,
dents and fellows. Everett has forgotten that will now be led by an alumni committee
more in Urology than I will ever know,”
Glenn Preminger MD, Division Chief, Duke
Urology.
Edward Everett Anderson was born in
Durham, North Carolina on May 10, 1932.
He was educated at Phillips Academy, entered Duke and received his BS in 1954 and
MD in 1958. He trained at Duke, Yale, the
Washington School of Medicine in Seattle
and the Peter Bent Brigham Hospital, Boston.
Everett Anderson
Education Fund
10
•
DUKE UROLOGY UPDATE
•
DYSURIA Committee
Co-Chairs
A new committee is being formed to
help manage and shape the future of DYSURIA. Drs. John Wiener and Jeff Taber will
be working to establish the committee to improve networking and communication; develop scientific and social programs, and
raise funds to support current Duke residents.
In 2014, DYSURIA will increase its networking opportunities and invites alumni to
attend the following events:
DYSURIA
Calendar 2014
April 5, 2014
DYSURIA Dinner at the
Duke Urology Assembly
Pinehurst, North Carolina
May 16, 2014 [tentative]
DYSURIA Cocktail Party at the AUA
Orlando, Florida
FALL 2013
June 20, 2014
DYSURIA 5th and 25th Year
Graduates at the Annual
Chief Residents’
Graduation Dinner
Durham, North Carolina
CONTINUING MEDICAL Duke
EDUCATION SECTION
Tuesday
Lecture
Series November
Duke Urologic Assembly
2014 Symposium
Dean G. Assimos, MD, Chairman of
Urology at the University of Alabama-Birmingham was the Duke Tuesday guest faculty
speaker on November 12. Dr. Assimos delivered the keynote lecture on “Urinary Oxalate:
How Did It Get There and How to Reduce It.”
Duke faculty speaking that day included
Stephen J. Freedland, MD (Lifestyle and
Prostate Diseases), Michael R. Harrison, MD
(GU Oncologist – Treatments for Metastatic
Renal Carcinoma), and Michael E. Lipkin, MD
(Imaging for Urolithiasis).
2014 Duke Tuesday
Education Series
Morris Center for
Research Lectureship
The 2013 Duke Tuesday in Urology, Morris Center for Research Lectureship was held
on July 23, 2013. The guest lecturer was
Thomas W. Jarrett, MD, Chairman of Urology
at George Washington University, who spoke
on “What is meant by Limited Life Expectancy
and How It Relates to Urologic Malignancies.”
Dr. Jarrett attended Duke University as an undergraduate with current Duke Urology faculty member, Dr. John Wiener and was the
Urology Residency Program Director at
George Washington University when current
Duke Faculty Member, Sherry Ross was a
trainee there.
The event was attended by over 100
members of the urologic community across
the state. Duke Urology continues to provide
invaluable educational forums to local, regional and national practicing urologists. The
Duke Tuesday Educational Series is held three
times per year, and provides local and regional
urologists with the opportunity to learn from
national leaders across the country.
The Morris Lectureship was made possible by the kind donation from the Morris Family Foundation.
February 11, 2014
Christopher Saigal, MD, MPH
Professor and Vice Chair of Urology,
UCLA
July 15, 2014
Morris Center for Research Lectureship
Joel B Nelson, MD
Professor and Chair of Urology
University of Pittsburgh School of Medicine
November 4, 2014
John E. Dees Lectureship
John W Brock III, MD
Professor and Chief,
Division of Pediatric Urology,
Monroe Carell Jr. Children’s Hospital,
Vanderbilt University
•
FALL 2013
History of the DUA
The Duke Urologic Assembly was established to meet the scientific and educational
needs of Duke Alumni and practicing urologists. The first meeting was held in 1966 in
the Jack Tar Hotel in Durham and was named
the Symposium Urologic Education.
Donations
To register for the Duke Tuesday Education Series for 2014 register at the Duke
CME Website or contact Robin Phillips,
CMECoordinator, robin.phillips@duke.
edu. This lecture series offers 3.0 PMA
Continuing Education Credits per lecture.
DUKE UROLOGY UPDATE
The 46th Annual Duke Urologic Assembly (DUA) will return to its roots and be held
April 3 – April 6, 2014 in the historic village
of Pinehurst for the first time since 1992.
This year’s format includes a dedicated day
focused on oncology. Thursday, April 3rd will
be the Duke Urologic Cancer Symposium
jointly hosted by Duke Urology and the Duke
Cancer Institute, with 13 Duke urologic oncologists, medical oncologists, and radiation
oncologists speaking on the latest diagnostic,
medical, and surgical aspects of urologic cancer management. Friday, April 4th – Sunday,
April 6th will be focus on urologic diseases
and treatments.
Attendees have the opportunity to
enjoy the spa facilities, family recreational activities, and any one of Pinehurst’s eight
world-class golf courses. As a special event,
a limited number of golf tee times on the
world famous Pinehurst No. 2 Golf Course
have been reserved for Friday afternoon. This
course will also host the US Open and US
Women’s Open Championships just two
months later. If you wish to play No. 2 that
day, please contact Robin Phillips at 919-6683532.
Registration information will be available on the Urology website at http://urology.surgery.duke.edu/cme. To reserve your
hotel room and tees for additional rounds of
golf, please call the Pinehurst Resort directly
at 1-877-403-2874. A block of rooms is
being held at a special rate but you will need
to book early as these are in high demand.
•
Charitable gifts are a driving force in the
current success and future achievements of
our physicians, educators, and scientists. If
you are interested in learning more about supporting Duke Urology, please contact Jillian
Ream, Duke Medicine Development and
Alumni Affairs, jillian.ream@duke.edu or
919-385-3197.
11
LEADING EDGE UROLOGY
46th DUKE UROLOGIC ASSEMBL
BL
LY
Y
and DUKE UROLOGIC
CANCER SYMPOSIUM
Thursday
y, April 3 – Sunday
nday
y, April 6,
y,
6 2014
PINEHURST CONFERENCE CENTER
in the historic village of PINEHURST
RST
T,, NORTH CAROLINA
Presented by
Duke Urology
Duke Cancer Institute
A Division of the Department of Surgery
Sponsored by
Duke University School of Medicine
12
•
DUKE UROLOGY UPDATE
•
FALL 2013
Agenda
Thursday, April 3, 2014
Session I ONCOLOGY: Localized Prostate Cancer
8:30 am
Welcome/Opening Remarks
8:35 am
Active Surveillance and Surgery
– Moul
8:55 am
Contemporary Radiation Therapy
– Lee
9:15 am
Hormones and Other Systemic
Therapies in Non-Metastatic
Prostate Cancer – George
9:35 am
Racial Disparities in Prostate
Cancer – Patierno
9:55 am
Case Discussion
10:20 am
Break
Session II ONCOLOGY: Advanced Renal Cell
Carcinoma
10:30 am
Differences in Outcome Between
Academic and Community
Medical Centers – Hirsch
10:50 am
Treatment Selection for Newly
Metastatic Kidney Cancer
– George
11:10 am
What To Do When First Line
Therapy Fails – Harrison
11:30 am
Case Discussion
12:00 pm
Lunch in Carolina Dining Room
5:00 pm
5:30 pm
Cutting Edge: Molecular Characterization of Prostate Cancer
– Harrison
Panel Discussion
Adjourn
Friday, April 4, 2014
Session VI ONCOLOGY: Renal Cell Carcinoma
8:00 am
Cytoreductive Nephrectomy and
Metastasectomy – Rampersaud
8:20 am
Surveillance of Renal Masses
– Uzzo
8:40 am
Management of Alternative
Histologies in RCC – George
9:00 am
Panel Discussion
9:20 am
Break
Session VII UROLOGY: Focal Therapy
9:30 am
Modern Imaging of Renal and
Prostate Tumors-Impact on Focal
Ablative Therapies – Gupta
9:50 am
Prostate Focal Therapy:
Cryotherapy and Nanoknife
– Polascik
10:10 am
Prostate HIFU – Robertson
10:30 am
Renal Focal Therapy: Cryotherapy
and Radiofrequency Ablation
– Polascik
10:50 am
Panel Discussion
11:10 am
Break
Session III ONCOLOGY: Bladder Cancer
1:00 pm
Surgery for Locally Advanced
Bladder Cancer – Inman
1:20 pm
Neo-adjuvant and Adjuvant
Therapy: Who Should Get It and
Why – Milowsky
1:40 pm
Chemoradiation for Bladder
Cancer – Lee
2:00 pm
Panel Discussion
2:20 pm
Break
Session IV ONCOLOGY: Immunotherapy in
Urologic Cancers
2:30 pm
Cancer and the Immune System:
The Basics – Nair
2:50 pm
Immunotherapy and Surgery
– Inman
3:10 pm
Immunotherapy in Renal Cell
Carcinoma: Is There Still a Role for
This – Inman
3:30 pm
Case Discussion
3:50 pm
Break
Session V ONCOLOGY: Advanced Prostate
Cancer
4:00 pm
Natural History and Hormonal
Therapy for Metastatic Prostate
Cancer – Freedland
4:20 pm
What To Do When Hormonotherapy Fails – George
4:40 pm
Session VIII UROLOGY: Other GU Malignancies
11:20 am
Embracing a Neoadjuvant
Approach for Upper Tract
Urothelial Tumors – Walther
11:40 am
Early Stage Testis Cancer: How to
Decide Which Avenue to Use
– Robertson
12:00 pm
Panel Discussion
12:20 pm
Adjourn
Saturday, April 5, 2014
Session IX UROLOGY: Stones
8:00 am
Adjuvant Medical Therapy
Following Surgical Stone
Management – Preminger
8:20 am
AUA Guidelines for Imaging
Known or Suspected Ureteral
Calculi – Lipkin
8:40 am
Ureteral Stone Management SWL v URS - Are we doing the
right thing – Scales
9:00 am
Panel Discussion
9:20 am
Break
10:10 am
10:30 am
10:50 am
11:10 am
Session XI UROLOGY: Renal Masses
11:20 am
Radiologic Work Up of Renal
Masses – Leder
11:40 am
VICTOR A. POLITANO
LECTURESHIP presented by Robert
Uzzo, MD – Nephrometry Scores
12:20 pm
Adjourn
Sunday, April 6, 2014
Session XII UROLOGY: Pelvic Floor & Male
Reconstruction
8:00 am
Management of Vesicovaginal
and Ureterovesical Fistulae – Le
8:20 am
Rectourethral Fistula; Algorithmic,
Team-based Approach to a
Complex Problem – Peterson
8:40 am
Pharmacotherapy for Benign
Urinary Tract Dysfunctions-State
of the Art 2014 – Fraser
9:00 am
Panel Discussion
9:20 am
Break
Session XIII UROLOGY: Andrology
9:30 am
AUA Vasectomy Guidelines
– Viviano
9:50 am
Non-Surgical Management of
Peyronie’s Disease: Options and
Efficacy – Lentz
10:10 am
Advances in Medical Therapy for
BPH – Scales
10:30 am
Testosterone Replacement
Therapy and Prostate Cancer: An
Update – Viviano
10:50 am
Panel Discussion
11:10 am
Break
Session XIV UROLOGY: Pediatrics
11:20 am
Contemporary Management of
Vesicoureteral Reflux – Routh
11:40 am
Urinary Tract Infection in the
Neurogenic Bladder: What We’ve
Learned – Ross
12:00 pm
Managing Pediatric Voiding
Dysfunction – Wiener
12:20 pm
Panel Discussion
12:40 pm
Closing Remarks
12:50 pm
Adjourn
Session X UROLOGY: Endourology/Robotics
9:30 am
UPJ Obstruction – Ferrandino
9:50 am
Robotics – Eaton
DUKE UROLOGY UPDATE
•
FALL 2013
Endoscopic Management of
Ureteral Strictures – Lipkin
Open Management of Ureteral
Strictures – Peterson
Panel Discussion
Break
•
13
Faculty
2014 CONFERENCE MEDICAL DIRECTORS
John S. Wiener, MD
Associate Professor of Surgery
Associate Professor in Pediatrics
Section Head, Pediatric Urology
Department of Surgery, Division of Urology
Duke University Medical Center
Michael R. Harrison, MD
Assistant Professor of Medicine
Department of Medicine, Division of Oncology
Member of the Duke Cancer Institute
Bradford R. Hirsch, MD
Assistant Professor of Medicine
Department of Medicine, Division of Oncology
Member in the Duke Clinical Research Institute
Daniel J. George, MD
Associate Professor of Medicine
Associate Professor in Urology
Director, GU Oncology, Duke Cancer Institute
Department of Medicine, Medical Oncology
Duke University Medical Center
Brant A. Inman, MD, MS, FRCSC
Cary N. Robertson, MD, Assistant Professor
Department of Surgery, Division of Urology
Member of the Duke Cancer Institute
Cary N. Robertson, MD
Associate Professor of Surgery
Practice Director, Duke Urology of Raleigh
Director, GU Surgical Oncology, Duke Raleigh
Cancer Center
Member of the Duke Cancer Institute
Richard A. Leder, MD
Associate Professor of Radiology
Clinical Associate in Surgery
Department of Radiology, Division of
Abdominal Imaging
Sherry S. Ross, MD
Assistant Professor of Surgery
Assistant Professor in Pediatrics
Director of Pediatric Urology Research
Director of Pediatric Urology Stone Clinic
Department of Surgery, Division of Urology
W. Robert Lee, MD, MEd, MS
Professor of Radiation Oncology
Associate Professor of Surgery
Department of Radiation Oncology
Member of the Duke Cancer Institute
GUEST FACULTY
Richard C. Rink, MD, FAAP, FACS
Robert A. Garrett Professor, Pediatric Urology
Riley Hospital for Children
Indiana University School of Medicine
Indianapolis, Indiana
Jonathan C. Routh, MD, MPH
Assistant Professor of Surgery
Assistant Professor in Pediatrics
Department of Surgery, Division of Urology
Aaron C. Lentz, MD
Assistant Professor of Surgery
Department of Surgery, Division of Urology
Matthew I. Milowsky, MD
Associate Professor of Medicine
Section Chief, Genitourinary Oncology Service
UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina
Michael E. Lipkin, MD
Assistant Professor of Surgery
Department of Surgery, Division of Urology
DUKE UNIVERSITY FACULTY
Samuel H. Eaton, MD
Assistant Professor
Department of Surgery, Division of Urology
Michael N. Ferrandino, MD
Assistant Professor of Surgery
Director, Minimally Invasive Urologic Surgery
Associate Residency Program Director
Department of Surgery, Division of Urology
Glenn M. Preminger, MD
James F. Glenn, MD, Professor of Urology
Chief, Division of Urologic Surgery
Department of Surgery, Division of Urology
Edward N. Rampersaud Jr., MD
Assistant Professor of Surgery
Department of Surgery, Division of Urology
Ngoc-Bich (Nikki) Le, MD
Assistant Professor of Surgery
Department of Surgery, Division of Urology
2014 Victor A. Politano, MD, Lectureship
GUEST FACULTY SPEAKER
Robert Uzzo, MD, FACS
G. Willing “Wing” Pepper Chair in Cancer Research
Professor and Chairman, Department of Surgery
Fox Chase Cancer Center
Temple University School of Medicine
Fox Chase Cancer Center
Philadelphia, PA
Thomas J. Polascik, MD
Professor of Surgery
Director, Society of Urologic Oncology Program
Director, Genitourinary Program on Focal Therapy
Department of Surgery, Division of Urology
Member of the Duke Cancer Institute
Charles D. Scales Jr., MD, MSHS
Assistant Professor of Surgery
Department of Surgery, Division of Urology
Member in the Duke Clinical Research Institute
Judd W. Moul, MD, FACS
James H. Semans, MD, Professor of Surgery
Professor of Anesthesiology
Department of Surgery, Division of Urology
Member of the Duke Cancer Institute
Charles J. Viviano, MD, PhD
Assistant Professor of Surgery
Department of Surgery, Division of Urology
Smita Kesavan Nair, PhD
Associate Professor of Surgery
Department of Surgery, Division of Surgical Sciences
Member of the Duke Cancer Institute
Philip J. Walther, MD, PhD, FACS
Professor of Surgery
Associate Professor of Pathology
Department of Surgery, Division of Urology
Chief of Urology, VA Medical Center, Durham
Member Duke Cancer Institute
Steven R. Patierno, PhD
Deputy Director, Duke Cancer Institute
Professor of Medicine
Department of Medicine, Division of Oncology
Matthew O. Fraser PhD
Associate Professor of Surgery
Department of Surgery, Division of Urology
David F. Paulson, MD
Professor Emeritus of Surgery
Department of Surgery, Division of Urology
Stephen J. Freedland, MD
Associate Professor of Surgery
Associate Professor in Pathology
Department of Surgery, Division of Urology
Member of the Duke Cancer Institute
Andrew C. Peterson, MD
Associate Professor of Surgery
Department of Surgery, Division of Urology
Rajan T. Gupta, MD
Assistant Professor of Radiology
Director, Abdominal Imaging Fellowship Program
Department of Radiology, Division of
Abdominal Imaging
14
•
DUKE UROLOGY UPDATE
•
FALL 2013
LEADING EDGE UROLOGY
46th DUKE UROLOGIC ASSEMBLY and DUKE UROLOGIC CANCER SYMPOSIUM
Thursdayy, April 3 – Sund
Sunday
dayy,, April 6, 2014
GOLF ACTIVITY
Featuring 8 unique golf courses, making it the largest golf resort in America, Pinehurst will be on the world’s
stage as the site of the 2014 U.S. Open and Women's Open Championships two short months after the
DUA conference. Duke has secured a very limited number of golf tee times on the world famous Pinehurst
ayy,, April 4, 2014. Due to extremely limited availability, golf is on a first come, first serve
Course No. 2 for Friday
basis. The Friday activity slots are being held for only a limited number of golfing participants until Friday,
November 8, 2013. TTo
o reserve your sleeping room and tee time, please call the Pinehurst resort directly at
1-877-403-2874. You
You may also reserve additional rounds of golf you wish to play at the same time.
TRA
AVEL
Pinehurst is situated at 80 Carolina Vista Drive in the Village of Pinehurst, North Carolina. Raleigh-Durham
International is the most accessible airport to the resort. Pinehurst offers special rates from RDU via their
in-house transportation department. Call (910) 235-8465 for reservations, which should be made at least
48 hours in advance. Once you're at Pinehurst, their in-house transportation team offers complimentary
shuttle service within the resort property. With a US or Canadian driver’s license, you may also enjoy use of
an Acura RL, TL, MDX, RDX or the new ZDX for up to 3 hours off-property as part of their complimentary
Acura Guest Drive Program.
y
Accommodations
HOTEL ACCOMMODA
MMODA
ATIONS
TIONS
Duke has reserved a block of rooms. TTo
o reserve your
room, please call the Pinehurst resort directly at
1-877-403-2874. At Pinehurst, you can meet all
morning and still enjoy the beauty of an afternoon
in the glorious Carolina sunshine, whether it's on the
course, the courts, or the bikes in the charming Village.
Registration
$150.00
$575.00
$675.00
$400.00
Physician Registration to Duke Urologic Cancer Symposium
(one day conference) includes Syllabus, Thursday Luncheon, and Reception
PA, NP
P,, RN Registration to Urologic Cancer Symposium
(one day conference) includes Syllabus, Thursday Luncheon, and Reception
REGISTER BEFORE February 27, 2014 for EARLLY
Y BIRD REGIS
REGISTRA
STRA
ATION
TION
for entire Leading Edge Urology
gy
y four day conference
Physician Early Registration to both Urologic Cancer Symposium and
Duke Urologic Assembly (four
( r day conference) includes Syllabus, Thursday
Luncheon, Reception, three breakfasts, breaks, and Saturday Luncheon
Physician Registration after February 27, 2014
Physician Registration to Urologic Cancer Symposium and
Duke Urologic Assembly (fou
( ur day conference)
PA, NP
P,, RN Registration to Urologic Cancer Symposium and Duke
U l i A
Urologic
Assembly
bly (four day conference) includes Syllabus, Thursday
Luncheon, Reception, three breakfasts, breaks, and Saturday Luncheon
REGISTRA
ATION WEBSITE
https://continuingeducation.dcri.duke.edu/2014-Leading-Edge-Urology
CANCELLA
ATION
TIO POLICY
All refund requests will be subject to a $100.00 processing fee.
No refunds will be issued after March 2, 2014.
Contact Information
Robin Phillips, Program Coordinatort robin.phillips@duke.edu or 919-668-3532
DUKE UROLOGY UPDATE
•
FALL 2013
•
15
on
$300.00
n
CONFERENCE REGISTRA
ATION
TION
First Class Mail
U.S. Postage
Duke Urology
PAI D
Division of the Department of Surgery
Permit No. 60
Durham, NC
Duke South, White Zone, Rm 1571-A
Mail: DUMC 3707, Durham, NC 27710
DUKE UROLOGIC ASSEMBLY • 2014 SYMPOSIUM
COURSE DESCRIPTION
With over eight decades of experience in caring for patients with urologic diseases, Duke’s Division of Urologic Surgery has established itself as
a world leader in urologic care, research, and education. The Duke Urologic Assembly began in
the 1970’s and was held annually at Pinehurst; we
are excited to return to our roots at Pinehurst for
the first time in decades. LEADING EDGE UROLOGY: 46th Annual Duke Urologic Assembly will
evaluate the most recent advances in the diagnostic evaluations, therapeutic options, management
of complications, and technologies that provide
leading edge care to patients. Participants will be
engaged through moderated discussions and interactive lectures on the latest evidence-based approaches to managing a wide range of urologic
conditions across the spectrum of life.
In partnership with our colleagues in the
Duke Cancer Institute we will designate Thursday
of the DUA for the DUKE UROLOGIC CANCER
SYMPOSIUM; a full day CME event featuring lectures by Duke and guest Medical Oncologists, Radiation Oncologists, and Urologists speaking on
the latest diagnostic, medical, and surgical aspects of urologic cancer management. There will
be separate as well as combined registration for
the Cancer Symposium with the DUA.
STATEMENT OF NEED
Improvements in the treatment of urologic
conditions generate a great need for knowledge
and up-to-date information for providers and
health care professionals. An outstanding roster
of speakers in a comprehensive, scientific program encompassing the sub-specialties of urology,
as well as medical and radiation oncologists treating urologic malignancies has been assembled.
This conference is an integral part of continuing
education for health care professionals nationwide.
TARGET AUDIENCE
Addressing current issues and technologies
in the practice of Urology, this conference will enhance knowledge in treating urologic conditions
and help improve patient care by Urologists; Medical Oncologists; Radiation Oncologists; Internal,
Family and Geriatric Medical Practitioners; Physician Assistants; Radiation Technicians; Nurse Practitioners; Nurses; Residents; and other Allied
Health Medical Staff.
LEARNING OBJECTIVES
• Evaluate and outline management options for
the patient with various urologic conditions
• Review the latest advances in the treatment of
advanced prostate cancer
• Identify latest updates in management of
bladder cancer, upper tract urothelial cancer,
renal cell carcinoma, and adrenal disorders
• Extend improved patient counseling and
generate patient satisfaction regarding therapy
choice
• Examine concepts of the medical management
of nephrolithiasis, as well as surgical therapy of
both renal and ureteral calculi
ACCREDITATION
The Duke University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide
continuing medical education for physicians.
CREDIT DESIGNATION
The Duke University School of Medicine designates this live activity for a maximum of 20
AMA PRA Category 1 Credit(s)™. Physicians
should only claim credit commensurate with the
extent of their participation in the activity.
Download