POREX Barrier Technology™
®
Antimicrobial Porous Materials for Medical Devices
Key Benefits
Genuine Porex™ : It works. Every time.
• Enhanced antimicrobial
performance
• Chlorhexidine widely
used in healthcare as an
antimicrobial agent
• Chlorhexidine alloyed in
porous polymer
• Porous molded structures can
be seamlessly integrated into
medical devices
• Porous plastic components
for venting, filtering, wicking
and diffusing applications
• Can be used in airborne and
fluid contact applications
• Porex patented antimicrobial
technology
Bactericidal
Virucidal
Fungicidal
The prevalence of hospital acquired infections has driven advances
in antimicrobial technologies. In 2003, Porex developed antimicrobial porous
media as an effective solution against bacteria and fungi. Continuing
its history of innovation, Porex has now developed Porex Barrier Technology,
a microbicidal technology that goes beyond inhibiting microbial growth
on surfaces; it kills microbes in liquid and gas streams on contact.
Porex Barrier Technology can be integrated into our porous media for venting,
filtering, wicking, and diffusing applications for medical devices. It is effective
against a broad spectrum of microbes, including gram positive and gram
negative bacteria, virus, and fungi. Porex Barrier Technology can be applied in
medical devices to help reduce infections caused by airborne and blood/fluid
contact exposures.
POREX Barrier Technology™
®
Antimicrobial Porous Materials for Medical Devices
JIS Z2801:2000 Test Methodology
The Japanese Industrial Standard JIS Z2801: 2000 or JIS Z2801 is an industrial standard
method to quantify antimicrobial activity level of an antimicrobial surface, especially for
a hydrophobic surface. The method provides reproducible quantitative results for both
microbiostatic and microbicidal properties for solid surfaces.
Staphylococcus aureus (gram pos)
Product
Initial CFU
24 hrs CFU
% Reduction
Log Reduction
Negative Control
3.3 x 10 6
3.7 x 10 6
-13
-0.05
Standard Product
(without CHX)
3.3 x 10 6
3.4 x 10 6
-2
-0.01
Barrier Technology
(with CHX)
3.3 x 10 6
<200
>99.994
>4.22
Potential Applications
Escherichia coli (gram neg)
Product
Initial CFU
24 hrs CFU
% Reduction
Log Reduction
Negative Control
2.4 x 10 6
2.9 x 10 7
-1212
-1.12
Standard Product
(without CHX)
2.4 x 10 6
2.8 x 10 7
-1075
-1.07
Barrier Technology
(with CHX)
2.4 x 10 6
<200
>99.9915
>4.07
Liquid Filtration
Liquid filtration testing was performed to measure the ability of Porex Barrier
Technology to remove E. coli from a liquid stream. In this test a small disk was placed
into a filter holder. The disk was challenged with 5.5 liters of water containing 690,000
CFU/ml of E. coli. The test was run at a flow rate of 1 liter per minute over a 5 minute
and 30 second time period. Samples of the effluent were taken at 4 different time
points during the test. The testing of the effluent samples showed no growth of E. coli.
Escherichia coli
Sample Time
Volume (L)
E. Coli Challenge
Counts (CFU/ml)
E. Coli Effluent
Counts (CFU/ml)
% Reduction
30 Sec
0.5
690,000
0
100
1 Min 30 Sec
1.5
690,000
0
100
3 Min 30 Sec
3.5
690,000
0
100
5 Min 30 Sec
5.3
690,000
0
100
Porex Corporation
500 Bohannon Road, Fairburn, GA 30213 USA
info@porex.com T. +1 770 964 1421 F. +1 770 969 0954
Airborne Infections
• Ventilator care devices
• Respiratory care
• Tracheal devices
• Suction canisters
• Central vacuum line systems
• Drug delivery inhalers
• Packaging
• Sterilization vents & trays
Blood/Fluid Contact Infections
• Fluid management/
IV components
• Catheters
• Dialysis devices
• Blood therapy devices
• Safety syringe vents
• Oral care devices
• Minimally invasive
surgical instruments
www.porex.com
800.241.0195
Porex Technologies GmbH
Strangenhäuschen 30, 52070 Aachen, Germany
info@porex.de T. +49 241 910525-0 F. +49 241 910525-16
Porex Technologies Sdn Bhd
Lot P.T. 74, Jalan Hulu Tinggi 26/6, Seksyen 26, Sektor A
Hicom Industrial Park, 40400 Shah Alam, Selangor, Malaysia
info_malaysia@porex.com T. +603 5191 3308 F. +603 5192 3308
©2014 Porex Corporation. POREX is a registered trademark and Porex Barrier Technology is a trademark of Porex Corporation. All Rights Reserved.
PXT-606-020812-01