5/18/2013 What can the surgeon do to minimize these complications? Complications of Inguinal Hernia Repair University of California, San Francisco Department of General Surgery Jonathan Carter, M.D. 1.Recurrent hernia 2.Chronic pain 3.Ischemic orchitis 4.Infection UCSF Postgraduate Course in General Surgery March 2013 What can the surgeon do to minimize these complications? Recurrence: Lap or Open? 1.Recurrent hernia 2.Chronic pain 3.Ischemic orchitis 4.Infection Randomized 2,164 patients with inguinal hernia to open Lichtenstein vs. laparoscopic (mostly TEP) repairs. Primary outcome = recurrence at 2 years Secondary outcomes = complications, death, pain 1 5/18/2013 Recurrence: Lap or Open? open Laparoscopic or Open? laparoscopic 2003 Meta-analysis of over 6,000 patients enrolled in randomized trials up to 2003 RECURRENCE: OR 0.81 p=0.16 Twice as many recurrences at 2 years with laparoscopic 10x as many life-threatening complications Laparoscopic or Open? NO DIFFERENCE!! Laparoscopic or Open? SUMMARY Randomized 1512 patients to TEP vs. Lichtenstein with 5 year FU 1/3 of TEP recurrences were from 1 surgeon After exclusion, TEP recurrence was 2.4% (vs 1.2% open) In centers of excellence, laparoscopic inguinal hernia repairs have about the same recurrence risk as open repairs. In the real-world, there may be twice as many recurrences with laparoscopy. But the absolute magnitude of the recurrence risk is small for both techniques. 2 5/18/2013 What mesh technique for open inguinal hernia repair has the lowest recurrence? Lichtenstein = Prolene Hernia System > mesh plug repair What can the surgeon do to minimize these complications? Fix or don’t fix? 1.Recurrent hernia 2.Chronic pain 3.Ischemic orchitis 4.Infection 3 5/18/2013 Laparoscopic or Open? Laparoscopic or Open? 2003 Persistent pain OR 0.54 p=0.001 in favor of laparoscopy Persistent numbness OR 0.38 p=0.01 in favor of laparoscopy PAIN What mesh technique for open inguinal hernia repair has the lowest pain? 4 5/18/2013 My choice: Lichtenstein Chronic pain Why? 1. Teach residents 2. No posterior mesh Makes redos easier! Lichtenstein = Prolene Hernia System > Mesh plug What can I do to reduce the risk of pain after open inguinal hernia repair? Identify all nerves POSSIBLE STRATEGIES Strategy 1: identify all 3 nerves Strategy 2: divide ilioinguinal nerve routinely Strategy 3: use lightweight mesh Strategy 4: use self adhesive mesh (minimal sutures) Strategy 5: use local nerve block 5 5/18/2013 Divide ilioinguinal nerve routinely? retrospective review of 90 patients, of whom 66 had routine nerve excision Dittrick 2004 Am J Surg pain Divide ilioinguinal nerve routinely? paresthesia Malekour 2008 Am J Surg Blinded randomized controlled trial 121 patients: 61 nerve excised, 60 nerve preserved Outcome = pain in first year (VAS) nerve excision nerve preservation p-value Pain POD1 2.2 ± 0.8 2.8 ± 0.7 <0.001 Pain POD30 0.7 ± 0.7 1.5 ± 0.7 <0.001 chronic pain 6% 21% 0.033 preserved excised preserved excised Mui 2006 Use lightweight mesh? Self-adhesive mesh? n=30 n=30 6 5/18/2013 Other pain reduction strategies Other pain reduction strategies More urinary retention with spinal anesthesia…. What can I do to reduce the risk of pain after open inguinal hernia repair? Strategy 1: identify all 3 nerves (recommended) What can the surgeon do to minimize these complications? 1.Recurrent hernia 2.Chronic pain Strategy 2: divide ilioinguinal nerve routinely (controversial) Strategy 3: use lightweight mesh (recommended) 3.Ischemic orchitis Strategy 4: use self adhesive mesh (controversial) Strategy 5: use local nerve block (recommended) 4.Infection 7 5/18/2013 open laparoscopic What can the surgeon do to minimize these complications? 1.Recurrent hernia 2.Chronic pain 3.Ischemic orchitis Advice: 1. Don’t dig a hernia sac out of the scrotum. Divide it. 4.Infection 2. For recurrent hernia, approach it from the opposite side. Otherwise risk of ischemic orchitis is 3-5% Infection risk Use of mesh increases infection risk slightly. Here antibiotics help: 2007 meta-analysis of six randomized trials 2507 patients Results prophylactic antibiotics controls Infections 1.38% OR 0.48 (0.27-0.85) 2.89% Most patients who develop a wound infection, even if polypropylene mesh is present, can be successfully treated by aggressive antibiotic treatment without the need to remove the prosthetic material. Ann Surg. 2007;245(3):392 8