BIOL/NEUR/PSY 240: Introduction to Neuroscience Lecture & Lab: Mickle 202 MWF 11am M 1pm Instructor: Dr. Greg Q. Butcher Office: 205 Mickle Hall Office hours: TR 9-12, WR 1-2:30p Office phone: 869-5545 (leave a message if necessary) e-mail: gbutcher@centenary.edu (best way to reach me) Course Summary Neuroscience is the study of the brain, spinal cord, and nervous system. It is an ever growing field that encompasses the techniques and methodologies of a broad range of disciplines including Psychology, Philosophy, Cellular & Molecular Biology, Genetics and, more recently, Economics, Marketing and even Law. This interdisciplinary nature allows for the examination of the nervous system at multiple levels, quite literally from molecule to mind. The main text book (Bear et al.), addresses many more topics than we will have time to cover in a single semester. Material will be presented at a much faster pace than in the prerequisite courses. I strongly encourage you to form a study group and to keep up on the reading. I will hold you accountable for all materials covered in lecture, lab, and the portions of the readings we discuss in class. This material is difficult and you should plan on an average of 6-12 hours work outside of class each week. Course Objectives: Upon finishing this course successfully, student will: Have a solid foundational understanding of neuroscience Have an introductory understanding of basic lab techniques common to molecular neuroscience Be able to generate, analyze and interpret data Be able to communicate complex topics in neuroscience to a public audience How does this course contribute to my overall biology education? In 2011, a group convened by the American Association for the Advancement of Science (AAAS) and the National Science Foundation (NSF) developed a description of five core concepts and six competencies that all biology students should master (Vision and Change in Undergraduate Biology Education: A Call to Action at www.visionandchange.org). This course provides an introduction to two core concepts and three of those competencies: Concepts Structure & Function: Basic units of structure define the function of all living things. Pathways and Transformations of Energy and Matter: Biological systems grow and change by processes based upon chemical transformation pathways and are governed by the laws of thermodynamics. Competencies Ability to apply the process of science Ability to tap into the interdisciplinary nature of science Ability to understand the relationship between science and society Texts Neuroscience Exploring the Brain 3rd Edition; Bear, Connors & Paradiso The Tell-Tale Brain, Ramachandran Plus assorted readings to be distributed through Blackboard Assessment Three Exams Lab Vlog discussions Brain Model Project Brain Awareness Week Project Grading: 60% 17.5% 8.5% 10% 10% Point Breakdown Exams (2 @150pts & 1 @ 250pts) Lab Vlogs (15 @ 5pts each) Brain Model Outreach Total 550 175 85 100 100 1010 Although 1010 points are possible in the course, your final grade will be taken out of 1000 A = 90-100% B = 80-89% C = 70-79% D = 60-69% Exams The three exams will consist of short answer & essay questions. Their purpose is to test your knowledge of the material and your ability to apply the information, not simply regurgitate or copy the work of others. The first two exams will cover only material from that unit. The third exam will be held during the scheduled final exam period and will be comprehensive. You are expected to following the Honor Code for these and all other assignments. Plagiarism and other forms of academic dishonesty will not be tolerated and will be immediately turned over to the Honor Court for investigation. Lab The lab portion of this course is designed to reinforce the lecture materials and present related topics only partially covered in lecture. Several of the labs will have data sheets and/or mini-reports for you to complete during the lab. Twice during the course, labs will extend over several weeks. In these instances you be required to prepare a formal lab report or a poster that covers the entire experiment. You will conduct these experiments and prepare the report/poster as a group, but each student should contribute to all parts of the assignment. Failure to contribute will result in a lower grade. Vlog discussions This semester we will explore some interesting (and in some cases controversial) topics in neuroscience. The Ramachandran book and other assigned readings will be the primary source material for these discussions. Each week you will prepare a video blog (vlog), in which you discuss your opinion of the reading or comment on another student’s submission. Although your submissions should be conversational in style, you will need to defend positions you take. For example, simply stating that “a reading is stupid” will not be adequate. If you disagree with the reading, tell us why and offer opposing evidence that supports your perspective. Your view on a topic will not affect your grade (i.e. I won’t deduct points if you disagree/dislike a reading), but the quality of your submissions will. You will start the semester with a perfect score (85pts) for this portion of the class. Post a new video each week that comments on a reading or responds to one posted by another student, Each submission should be at least one minute in length, although they may certainly be longer. Submissions must be available for viewing no later than noon on Wednesdays so that we can use the content during in-class discussions on select Fridays. Depending on the length of the video and the speed of your connection, uploading may take some time. It is your responsibility to plan for technical delays. Waiting until 11:55 on Wednesday is a bad idea and will likely result in late penalties. In general, I would suggest you try to upload videos by Tuesday to avoid this issue. The one exception to this rule is the first week of class. Everyone has until Wednesday the 16th to post your first (and second) videos. Failure to meet these requirements will result in the loss of 5 points for each instance (up to the full 85pts). I will evaluate each submission, although they will not be graded for content. I will not deduct points for weak posts in your early videos, but I will point out areas that need improvement (poor lighting, inadequate defense of an argument, etc.). If you ignore these warnings, later videos will not count toward your total and will cost you points. The style of each video is up to you. However videos that are too dim to see, or have too much background noise, will not be acceptable. We want to hear what you have to say. Recording your video in the caf during lunch or in a closet without enough light, won’t allow us to do this. There are numerous online guides to help you as you learn how to record and post videos. Chances are also pretty good that others in your group have far more experience with this medium than I do and will likely be able to help those of you who are new to YouTube. However, if you do have questions, or aren’t certain how to post entries, let me know. You will each be assigned to a YouTube account I’ve already established. Each member will have full access to this account. Although you are welcome to view and comment to any of the videos your 15 posts must be submitted to your assigned group’s channel. Brain Model & BAW projects – see attached sheets Attendance You are expected to be in class and lab on time every day. I will close and lock the door at the beginning of class, if you are not in class by that time you may be locked out for the day. If you miss a lecture, it is your responsibility to obtain the notes and/or homework. The lab portion of this class will consist of computer simulations, hands-on “wet-labs” and multi-week experiments. Therefore, in some cases, it will not be possible to make up a missed lab experiment. If you are absent for a lab you are responsible for all material covered during that lab. If you are absent for an exam, it is your responsibility to notify me within 24hrs of the absence or you will receive a zero. If you have an athletic or academic event that will force you to miss class, you must make arrangements with me at least one week in advance or any missed work will receive a zero. If you are ill you may be able to make up the missed work provided you contact me within 24 hours of the missed class/lab and provide signed note from a doctor. E-mail & Blackboard I expect you to check your Centenary e-mail and Blackboard regularly for course information. I distribute information about exams, assignments and readings via e-mail and/or Blackboard. Lecture & Laboratory Guidelines Unless I explicitly state that an assignment is to be completed as a group, I expect all work to be completed independently. Copying the work of others is cheating and will be immediately turned over to the Honor Court. Use of online material without proper citation also constitutes plagiarism and will also be turned over to the HC. Food and drink will be allowed during lecture as long as containers are disposed of properly and they do not become a distraction. For your safety, food and drinks will not be allowed during certain labs. You may leave these items on the table out side of the lab room Computers may be used to take notes during class. However, you will lose this privilege if you use the computers for non-class activities (gaming, facebook, etc.). At the beginning of every class period you should place your phone in the receptacles located near the door. They may not be used during class. If you are expecting an emergency phone call, please inform me before class starts. Sleeping in class is also a distraction to others. If you fall asleep, your student colleagues and I will awaken you as we see fit (Nerf gun, cold water, etc…). Accommodations It is the policy of Centenary College to accommodate students with disabilities, pursuant to federal law, state law, and the College's commitment to equal educational opportunities. Any student with a disability who needs accommodations, for example in seating placement or in arrangements for examinations, should inform the instructor at the beginning of the course. Students with disabilities need to contact Disability Services (a division of Counseling Services), which is located in the ground floor of Rotary Hall to obtain services. Telephone 318-869-5466/5424. Proposed Schedule Dates Jan 7-11 Jan 14-18 Week Topic Assignments Lab Text Chapters 1 NOTE: No class or lab on Monday Jan 7 th. Bear 1 & 7 History of NS & Neuroanatomy Posted on Blackboard 2 Cells of the Nervous System Bear 2 Discussion of Brain Awareness Week Projects & Sheep Brain Dissection Readings for Youtube blogs Ramachandran: No Mere Ape Ramachandran 1 . Jan 21-25 3 NOTE: Monday’s class is canceled for MLK day. Ramachandran 4 Lab will meet on Friday afternoon from 2-5p. Neuronal communication Bear 4 & 5 BAW outreach activity: outline due Jan 21 Brain model structure list, finalized in class Jan 25 Tissue preparation & Introduction to literature searches Jan 28 - Feb 1 4 Neuronal Comm. Cont. & Neurotransmitters Bear 4, 5 & 6 Ramachandran 5 Toilet Talk Flyer idea summary due Feb 1 Bring background articles to lab Immunohistochemical (IHC) labeling & Poster design Feb 4-8 5 Neurotransmitters Feb 11-15 6 Feb 18-22 Feb 25-March 1 7 Bear 6 Ramachandran 2 Microscopy – Bright-field / Fluorescent & Poster completion BAW outreach activity summary due Feb 4 Draft of Toilet talk flyer due Feb 8 NOTE: Monday and Wednesday’s classes are canceled for Mardi Gras Holiday. The exam will be held on Friday afternoon from 2-5p. The Eye & Central Vision Bear 9 & 10 Ramachandran 3 Exam 1 (covers material through neurotransmitters; 150pts) Final draft of poster due & in-class poster presentation Feb 11 Final Toilet Talk Flyer due Feb 15 Auditory and vestibular system Bear 11 Brain Model & Atlas due by Feb 22 Sensory lab Somatosensory Bear 12 Bring all supplies for your outreach activity to lab Brain model critique & BAW trial run Ramachandran 7 Ramachandran 8 Dates March 4-8 Week 8 Topic Motor control: Spinal Assignments Lab Reading(s) Bear 13 Blogs topics Blackboard article Motor Lab March 11-15 9 Brain Awareness Week Sign up for time at Sci Port Bring all supplies for BAW outreach activity none Blackboard article March 18-22 10 Motor control: Central Motor lab write-up due March 22 Bear 14 Blackboard article March 25-29 Spring Break: No Class or lab April 1-5 11 Motor continued / Language April 8-12 12 Language / Sex & the Brain BAW outreach activity reflection essay due April 12 April 15-19 13 Sex and the Brain Blackboard article April 22-26 14 Catch up OR Molecular Memory Bear 25 SDN lab report due 5pm April 26 Sexually Dimorphic Neurons (SDN) II Ramachandran 9 Final Exam 3 given during scheduled final (Comprehensive; 250pts) Bear 20 Ramachandran 6 Monday Exam 2 (covers material through Motor; 150pts) Bear 17 Blackboard article Sexually Dimorphic Neurons (SDN) I Draft of SDN-Introduction & Methods sections due April 19 Blackboard article