Fundamental Virology MIMM 324 Fall Term, 2004 TERM PAPER TOPIC ASSIGNMENTS Students are assigned to groups based on alphabetical order of last names. If you are assigned to a particular group, you must find a research paper concerning any virus of your choice that is within that group, and write a summary of that research paper. Please follow instructions on term paper handout (available on course web site http://132.216.13.9/virology). Last name begins with Virus group Lecturer Rao-Z Bacteriophages Acheson Leu-Rah DNA-containing animal viruses Acheson F-Lee RNA-containing animal viruses, viroids, prions Pause, Briedis Retroviruses, Hepadnaviruses Hiscott, Gotte A-E Fundamental Virology MIMM 324 Fall Term, 2004 MEMO on TERM PAPERS Each student registered in this course will be required to find an original research paper in the scientific literature, read the paper, and write a 2-3 page resumé of its principal findings. This project will introduce students to finding papers in scientific journals and will allow students to familiarize themselves with the way in which research in virology leads to the accumulation of new knowledge about viruses. The resumé, along with a photocopy of the paper, must be handed in on or before Friday, November 26, 2004 at 4:00 p.m. You are encouraged to carry out this project during the course, and not wait until the last minute; we will accept completed papers at any time before November 26. However, papers handed in after the deadline will not be accepted. Since this course is organized into four sections covering different virus groups, term papers will be assigned to each of the four sections of the course: bacteriophages, DNA viruses, RNA viruses, and retroviruses/hepatitis B virus. Instructors teaching each section will grade the papers, which will be graded and returned at the beginning of the winter term. Topics will be assigned by alphabetical order, once the class list is established, and will be posted, probably during the second week of the term. If you are assigned to a particular virus group, you will be required to find a research paper concerning any virus of your choice that is within that group. You can find papers on the virus you have chosen by looking at recent volumes of a large number of biomedical journals, a brief but incomplete list of which follows: Journal of Bacteriology Journal of Virology Journal of General Virology Virology Virus Research Molecular and Cell Biology Cell Science Nature Nucleic Acids Research Oncogene Biochemistry You should limit your search to papers that have appeared in the past four years: that is, published in 2001, 2002, 2003 or 2004. These and many other journals can be found in the McIntyre Health Sciences Library, and can be searched by computer using Ovid (www.health.library.mcgill.ca/database/medline.htm), a program that locates references based on a number of criteria, or PubMed (www.ncbi.nlm.nih.gov), of the US National Library of Medicine. If using Ovid you should use the Medline database. Both Ovid and PubMed are accessible directly at the McIntyre Health Sciences Library, from computers connected to the McGill network, or from home via your connection to the McGill server. There are a number of computers linked to the McGill network and available for the exclusive use of undergraduate science students, located at level C of the Lyman Duff Building, in the lobby in front of the student laboratories. The paper on which you report must be an original scientific paper, showing data from experiments, and must not be a review article. Review articles summarize information from other papers containing data and conclusions, and are usually, but not always, in specialized review journals. You may find it necessary to read a few other papers to understand background information in the paper you have chosen. The paper you choose should be based on laboratory experiments, not on surveys or epidemiological studies. Your resumé must be submitted in the following format: 3 pages, 1 1/2 or double spaced, 12-point type, 1-inch margins all around. Do not use any figures; your resumé can refer to data figures or tables in the paper covered. Add a title page listing the title of the article, the journal, year, volume and first and last pages of the article, as well as your name and student number. Staple your resumé to a photocopy of the article you have chosen. This project will be graded on the following criteria: evidence that you have made an effort to understand and explain the contents of the paper you have chosen; clarity of writing and organization of your resumé; interest and relevance of the article to virology as presented in this course. The project will count for 10% of your final grade in this course. IMPORTANT NOTICE! Please make all efforts to avoid plagiarism while writing this term paper. Because this assignment asks for a summary of a published research paper, the possiblities of plagiarism are reduced compared to, say, a term paper on a broader topic. However, you should not simply copy passages from the paper you are reviewing, as that could be plagiarism. Once you have understood the research paper, explain it in your own terms. For information and hints about how to avoid plagiarism, which is a major academic offense, please see www.mcgill.ca/integrity/studentguide/