Study information form Title of the study Health Outcomes and Lifestyle in a Sample of people with Multiple Sclerosis: the HOLISM study Name of the institution responsible for the study St Vincent’s Hospital Melbourne, Australia Recruitment dates May 2012 – July 2012 About the study There is strong evidence to suggest that lifestyle plays an important role in health outcomes in Multiple Sclerosis. To explore this relationship, the research team is asking people with MS to complete an online questionnaire about factors related to their lifestyle (e.g. diet, exercise, sun exposure, vitamin D, Omega-3 supplementation, stress reduction) and their health-related quality of life, among other questions. Over time, the researchers intend to follow this group at yearly intervals to see if there is a relationship between changes in these lifestyle factors and the health of the group. The researchers will then analyse this information to determine which factors best predict the health of people with MS. Potentially this research may answer some of the most vexing questions in MS. Those related to consumption of particular foods and fats, vitamin D and sun exposure, and the influence of meditation on disease progression among other important findings. What will participants be asked to do? Participants will be asked to read some information about the study before giving their consent to participate. The questionnaire will then be completed online, in participants’ own time. We estimate this will take 30 – 40 minutes, but participants can exit and re-enter at any time to update their responses. The research team will contact the participants by email annually to invite them to participate again, should they wish to do so. Who can take part? Anyone who has a probable or definite diagnosis of MS and is over 18 years of age. You can be living anywhere in the world, but the survey is conducted in English. Who is conducting the research? The principle investigator is Prof George Jelinek, administrator of the Overcoming Multiple Sclerosis website and a researcher. He is joined by a research team with an interest in MS and lifestyle. Who has reviewed this study? St Vincent’s Human Research Ethics Committee in Australia has reviewed and approved this study (LRR 055/12). Data and contact details will be held outside the UK and therefore won't be subject to UK law. Interested? If you would like to find out more about this study, please read the participant information sheet by going to www.surveymonkey.com/s/HOLISM or contact research officer Emily Hadgkiss at [email protected] Please note that enquiring about participation does not commit you in any way.